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[CD4+ and CD8+ Regulatory T cells: Key Players in Human Autoimmunity]. [CD4+和CD8+调节性T细胞：人类自身免疫的关键角色]。
IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences
Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1051/medsci/2025203
Jade Andrieu, Lauryn Sarng, Ana Fitahiantsoa Ratolojanahary
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引用次数: 0
[Opposing roles of the pro-oncogenic kinase PAK1 and the tumor suppressor NF2/Merlin in myelin formation by oligodendrocytes]. [促癌激酶PAK1和肿瘤抑制因子NF2/Merlin在少突胶质细胞髓磷脂形成中的相反作用]。
IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences
Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1051/medsci/2025247
Noémie Adès, Lucas Baudouin, Lamia Bouslama-Oueghlani
{"title":"[Opposing roles of the pro-oncogenic kinase PAK1 and the tumor suppressor NF2/Merlin in myelin formation by oligodendrocytes].","authors":"Noémie Adès, Lucas Baudouin, Lamia Bouslama-Oueghlani","doi":"10.1051/medsci/2025247","DOIUrl":"https://doi.org/10.1051/medsci/2025247","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 1","pages":"30-32"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ubiquitination and degradation of MHC-II by TIM-3 inhibit antiviral immunity]. [TIM-3的泛素化和MHC-II降解抑制抗病毒免疫]。
IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences
Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1051/medsci/2025201
Aude Bourgeteau, Romane Deteve
{"title":"[Ubiquitination and degradation of MHC-II by TIM-3 inhibit antiviral immunity].","authors":"Aude Bourgeteau, Romane Deteve","doi":"10.1051/medsci/2025201","DOIUrl":"https://doi.org/10.1051/medsci/2025201","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 1","pages":"105"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Neuroblastoma: A paediatric malignancy shaped by its embryonic origin]. 神经母细胞瘤：一种由胚胎起源形成的儿科恶性肿瘤。
IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences
Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1051/medsci/2025242
Audrey Prunet, Valérie Castellani
{"title":"[Neuroblastoma: A paediatric malignancy shaped by its embryonic origin].","authors":"Audrey Prunet, Valérie Castellani","doi":"10.1051/medsci/2025242","DOIUrl":"https://doi.org/10.1051/medsci/2025242","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 1","pages":"16-18"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Virus-like capsids proteins released by tumors underlie neurological disorders]. [肿瘤释放的病毒样衣壳蛋白是神经系统疾病的基础]。
IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences
Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1051/medsci/2025206
Sirine Ben Amor, Rokhaya Gaye
{"title":"[Virus-like capsids proteins released by tumors underlie neurological disorders].","authors":"Sirine Ben Amor, Rokhaya Gaye","doi":"10.1051/medsci/2025206","DOIUrl":"https://doi.org/10.1051/medsci/2025206","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 1","pages":"102"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[How an antibiotic resistance mechanism promotes bacterial virulence]. [抗生素耐药性机制如何促进细菌毒力]。
IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences
Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1051/medsci/2025252
Audrey Goman, Lola Manenc, Cecile Goursat, Priscilla Branchu, Eric Oswald

Pseudomonas aeruginosa, a major cause of severe hospital-acquired infections, is a bacterial pathogen whose increasing resistance to antibiotics poses a significant public health threat. The cprA gene, known to confer resistance to colistin, a last-resort antibiotic, also plays a critical role in the production of specific bacterial extracellular vesicles. When the bacteria is exposed to colistin, these vesicles display enhanced capacity to activate the inflammasome, a process associated with a blockage of autophagic flux. Thus, the induction of cprA expression in response to colistin not only promotes antibiotic resistance but also amplifies bacterial virulence by exacerbating inflammation.

铜绿假单胞菌是严重医院获得性感染的主要原因，是一种细菌病原体，其对抗生素的耐药性日益增强，对公共卫生构成重大威胁。cprA基因，已知赋予对粘菌素（最后的抗生素）的抗性，在特定细菌细胞外囊泡的产生中也起着关键作用。当细菌暴露于粘菌素时，这些囊泡表现出增强的激活炎性体的能力，这一过程与自噬通量的阻塞有关。因此，诱导cprA表达响应粘菌素不仅促进抗生素耐药性，而且通过加剧炎症放大细菌毒力。
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引用次数: 0
[Histone]. (组蛋白)。
IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences
Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1051/medsci/2025258
Anna Salvetti
{"title":"[Histone].","authors":"Anna Salvetti","doi":"10.1051/medsci/2025258","DOIUrl":"https://doi.org/10.1051/medsci/2025258","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 1","pages":"88"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Gasdermin D, an enhancer of the inflammatory response to influenza virus]. [Gasdermin D，一种对流感病毒的炎症反应增强剂]。
IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences
Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1051/medsci/2025204
Orianne Chaold, Victoria Lassinat, Ilhona Marques
{"title":"[Gasdermin D, an enhancer of the inflammatory response to influenza virus].","authors":"Orianne Chaold, Victoria Lassinat, Ilhona Marques","doi":"10.1051/medsci/2025204","DOIUrl":"https://doi.org/10.1051/medsci/2025204","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 1","pages":"106"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Structure of the influenza virus ribonucleoprotein: a model for understanding the viral replication machinery]. [流感病毒核糖核蛋白的结构：理解病毒复制机制的模型]。
IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences
Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1051/medsci/2025241
Allison Ballandras-Colas, Alice J Stelfox, Rob W H Ruigrok, Thibaut Crépin
{"title":"[Structure of the influenza virus ribonucleoprotein: a model for understanding the viral replication machinery].","authors":"Allison Ballandras-Colas, Alice J Stelfox, Rob W H Ruigrok, Thibaut Crépin","doi":"10.1051/medsci/2025241","DOIUrl":"https://doi.org/10.1051/medsci/2025241","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 1","pages":"9-12"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus]. [β-葡聚糖重编程中性粒细胞以促进对甲型流感病毒的疾病耐受性]。
IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences
Pub Date : 2026-01-01 Epub Date: 2026-01-23 DOI: 10.1051/medsci/2025202
Solène Ozil, Éva Todorovska, Samuel Terki, Maria Del Mar Naranjo-Gomez
{"title":"[β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus].","authors":"Solène Ozil, Éva Todorovska, Samuel Terki, Maria Del Mar Naranjo-Gomez","doi":"10.1051/medsci/2025202","DOIUrl":"https://doi.org/10.1051/medsci/2025202","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 1","pages":"104"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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