Bartosz Barzak, Kornelia Hankus, Anna Mielczarek, Slawomir Wozniak
Abstract This review examines the role of the physiotherapist in diagnosing piriformis muscle syndrome (PS), taking into account the exact anatomy of the muscle and the arsenal of tests the physiotherapist can use. In the works we researched, talking about PS ignores the role of the physiotherapist as the first specialist the patient should turn to. Many works emphasize the physician’s physical examination and often surgical intervention. The participation of a physiotherapist in the process of diagnosing ailments such as PS requires further research, but already with a high degree of reliability, a physiotherapeutic examination can speed up the process of diagnosis and treatment.
{"title":"The piriformis muscle syndrome – anatomy, diagnosis and the role of physiotherapy. A Review","authors":"Bartosz Barzak, Kornelia Hankus, Anna Mielczarek, Slawomir Wozniak","doi":"10.2478/acb-2023-0006","DOIUrl":"https://doi.org/10.2478/acb-2023-0006","url":null,"abstract":"Abstract This review examines the role of the physiotherapist in diagnosing piriformis muscle syndrome (PS), taking into account the exact anatomy of the muscle and the arsenal of tests the physiotherapist can use. In the works we researched, talking about PS ignores the role of the physiotherapist as the first specialist the patient should turn to. Many works emphasize the physician’s physical examination and often surgical intervention. The participation of a physiotherapist in the process of diagnosing ailments such as PS requires further research, but already with a high degree of reliability, a physiotherapeutic examination can speed up the process of diagnosis and treatment.","PeriodicalId":18329,"journal":{"name":"Medical Journal of Cell Biology","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135688672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wiktoria Świątek, Olgierd Kłodziński, Julia Brzęczek, Ignacy Kosiorowski, Natalia Grzybowska, P. Mozdziak, W. Kranc
Abstract Fascia continues to be a significant topic in numerous studies due to its unique functions that contribute to maintaining various bodily functions. The current article focuses on the crucial aspects of fascia and provides an essential collection of basics to understand the phenomenon of fascia. It describes the anatomical structure, with emphasis on the division into layers. Furthermore, the article explains how fascia affects muscle movement and transduction signals. In addition to the significant role of fascia, the article discusses its components, both cellular and non-cellular. Regarding cellular factors, various types of cells are distinguished and their role in mechanotransduction is explained. Non-cellular components maintain the structure of the fascia and provide scaffolding for the cells of the fascia. The problem of fascia classification is comprehensively considered, including the anatomical, histological, and cellular aspects of fascia. Finally, the article examines aspects of fascia disorders, particularly rheumatoid arthritis, as well as the correlation of structural abnormalities with lymphatic oedema. Not only does it address these abnormalities, but it also discusses the nature of myofascial pain origin and the currently widespread topic of acupuncture.
{"title":"Components of the fascia – cells and extracellular matrix","authors":"Wiktoria Świątek, Olgierd Kłodziński, Julia Brzęczek, Ignacy Kosiorowski, Natalia Grzybowska, P. Mozdziak, W. Kranc","doi":"10.2478/acb-2023-0002","DOIUrl":"https://doi.org/10.2478/acb-2023-0002","url":null,"abstract":"Abstract Fascia continues to be a significant topic in numerous studies due to its unique functions that contribute to maintaining various bodily functions. The current article focuses on the crucial aspects of fascia and provides an essential collection of basics to understand the phenomenon of fascia. It describes the anatomical structure, with emphasis on the division into layers. Furthermore, the article explains how fascia affects muscle movement and transduction signals. In addition to the significant role of fascia, the article discusses its components, both cellular and non-cellular. Regarding cellular factors, various types of cells are distinguished and their role in mechanotransduction is explained. Non-cellular components maintain the structure of the fascia and provide scaffolding for the cells of the fascia. The problem of fascia classification is comprehensively considered, including the anatomical, histological, and cellular aspects of fascia. Finally, the article examines aspects of fascia disorders, particularly rheumatoid arthritis, as well as the correlation of structural abnormalities with lymphatic oedema. Not only does it address these abnormalities, but it also discusses the nature of myofascial pain origin and the currently widespread topic of acupuncture.","PeriodicalId":18329,"journal":{"name":"Medical Journal of Cell Biology","volume":"11 1","pages":"13 - 19"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49210657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natasza Leśków, Z. Karp, Mateusz Banaszewski, K. Popielska, Michalina Grześkowiak, Jakub Mikołajski, P. Mozdziak, W. Kranc
Abstract Wound healing involves four stages: haemostasis, inflammation, proliferation, and remodelling. Each wound should be considered separately because of the tissue’s different environment. The key to successful wound healing is cell signalling and synchronisation between cells and chemical transmitters, which gradient attracts immune cells and prevents pathogens from causing infection. Both skin and oral mucosa stages of the wound healing process are the same. Nonetheless, some differences affect the outcome of the healing. The most critical factors that impact the process are the time required for wound closure or immune response, the presence of saliva, the level of anti-inflammatory cytokines, and extracellular matrix (ECM) remodelling. Compared to the skin, wounds in the oral mucosa heal much faster and without scarring. Saliva plays a crucial role in healing the oral mucosa – because of higher levels of tissue factor, it reduces the clotting time. Furthermore, it is rich in many growth factors stimulating wound healing. Mesenchymal stem cells are yet another valid matter regarding wound healing in oral mucosa. Outstanding properties of these cells exhibit potential to be applied for therapeutical purposes. Additionally, immune cells’ participation and response to tissue damage are more substantial and faster in the oral mucosa than in the skin. Wound healing is a complex process influenced by many factors, including hyperglycaemia in diabetes, smoking, alcohol, and levels of sex hormones. Some of them, such as smoking, impair all stages of healing, while others only have some elements.
{"title":"Characteristics and cellular mechanism of the wound healing process in the oral mucosa","authors":"Natasza Leśków, Z. Karp, Mateusz Banaszewski, K. Popielska, Michalina Grześkowiak, Jakub Mikołajski, P. Mozdziak, W. Kranc","doi":"10.2478/acb-2023-0001","DOIUrl":"https://doi.org/10.2478/acb-2023-0001","url":null,"abstract":"Abstract Wound healing involves four stages: haemostasis, inflammation, proliferation, and remodelling. Each wound should be considered separately because of the tissue’s different environment. The key to successful wound healing is cell signalling and synchronisation between cells and chemical transmitters, which gradient attracts immune cells and prevents pathogens from causing infection. Both skin and oral mucosa stages of the wound healing process are the same. Nonetheless, some differences affect the outcome of the healing. The most critical factors that impact the process are the time required for wound closure or immune response, the presence of saliva, the level of anti-inflammatory cytokines, and extracellular matrix (ECM) remodelling. Compared to the skin, wounds in the oral mucosa heal much faster and without scarring. Saliva plays a crucial role in healing the oral mucosa – because of higher levels of tissue factor, it reduces the clotting time. Furthermore, it is rich in many growth factors stimulating wound healing. Mesenchymal stem cells are yet another valid matter regarding wound healing in oral mucosa. Outstanding properties of these cells exhibit potential to be applied for therapeutical purposes. Additionally, immune cells’ participation and response to tissue damage are more substantial and faster in the oral mucosa than in the skin. Wound healing is a complex process influenced by many factors, including hyperglycaemia in diabetes, smoking, alcohol, and levels of sex hormones. Some of them, such as smoking, impair all stages of healing, while others only have some elements.","PeriodicalId":18329,"journal":{"name":"Medical Journal of Cell Biology","volume":"11 1","pages":"1 - 12"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45297538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The understanding and explanation of inflammation-dysplasia-cancer sequence is challenging. The gut microbiota is an important factor for the intestine wall. The changes in bacteria quality and/or quantity (dysbiosis) may begin the colon inflammation. This paper reviewed the gut microbiome risk factors which may lead to colon cancer.
{"title":"Gut Microbiota and its impact on the inflammation-dysplasia-cancer sequence","authors":"Ivanna Lazarchuk, Shivika Parmar, Slawomir Wozniak","doi":"10.2478/acb-2023-0004","DOIUrl":"https://doi.org/10.2478/acb-2023-0004","url":null,"abstract":"Abstract The understanding and explanation of inflammation-dysplasia-cancer sequence is challenging. The gut microbiota is an important factor for the intestine wall. The changes in bacteria quality and/or quantity (dysbiosis) may begin the colon inflammation. This paper reviewed the gut microbiome risk factors which may lead to colon cancer.","PeriodicalId":18329,"journal":{"name":"Medical Journal of Cell Biology","volume":"11 1","pages":"28 - 32"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47536999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivanna Lazarchuk, Bartosz Barzak, Slawomir Wozniak, A. Mielczarek, V. Lazarchuk
Abstract In Poland, cholelithiasis affects approximately 20% of the population and require approximately 45.000 cholecystectomies per year. Women, especially mature women, are more at risk of developing this condition. Hormonal and reproductive factors are the reason for higher incidence in women. In this publication, we review significant factors affecting this situation. The anatomical structure of the gallbladder may have a significant impact on the course of the cholecystectomy, and the occurrence of any intra- or post-operative complications. The pathomechanism of cholelithiasis is described, as well as the basic risk factors.
{"title":"Cholelithiasis – a particular threat to women. A review of risk factors","authors":"Ivanna Lazarchuk, Bartosz Barzak, Slawomir Wozniak, A. Mielczarek, V. Lazarchuk","doi":"10.2478/acb-2023-0003","DOIUrl":"https://doi.org/10.2478/acb-2023-0003","url":null,"abstract":"Abstract In Poland, cholelithiasis affects approximately 20% of the population and require approximately 45.000 cholecystectomies per year. Women, especially mature women, are more at risk of developing this condition. Hormonal and reproductive factors are the reason for higher incidence in women. In this publication, we review significant factors affecting this situation. The anatomical structure of the gallbladder may have a significant impact on the course of the cholecystectomy, and the occurrence of any intra- or post-operative complications. The pathomechanism of cholelithiasis is described, as well as the basic risk factors.","PeriodicalId":18329,"journal":{"name":"Medical Journal of Cell Biology","volume":"11 1","pages":"20 - 27"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43352833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract This review examines how physical activity can modulate the gut microbiota, taking into account the training intensity used, the value of the load and the age group studied. The aim of the study is to show the significant interaction between exercise and its effects on the gut microbiota. Many of the studies we analysed showed an interesting correlation between the physical activity undertaken and the change in biodiversity and taxon representation, so we concluded that exercise can significantly modulate the composition of the gut microbiome. This also works the other way around, as doing too much intense and taxing exercise can lead to so-called intestinal dysbiosis, which promotes inflammatory reactions and other unfavourable metabolic consequences. Therefore, in this review, we have analysed the latest and most interesting body of literature oscillating around the complex relationship between the movement undertaken and its impact on the microbiome.
{"title":"The effect of physical activity on gut microbiota. A review","authors":"Bartosz Barzak, Kornelia Hankus, Shivika Parmar, Slawomir Wozniak","doi":"10.2478/acb-2022-0021","DOIUrl":"https://doi.org/10.2478/acb-2022-0021","url":null,"abstract":"Abstract This review examines how physical activity can modulate the gut microbiota, taking into account the training intensity used, the value of the load and the age group studied. The aim of the study is to show the significant interaction between exercise and its effects on the gut microbiota. Many of the studies we analysed showed an interesting correlation between the physical activity undertaken and the change in biodiversity and taxon representation, so we concluded that exercise can significantly modulate the composition of the gut microbiome. This also works the other way around, as doing too much intense and taxing exercise can lead to so-called intestinal dysbiosis, which promotes inflammatory reactions and other unfavourable metabolic consequences. Therefore, in this review, we have analysed the latest and most interesting body of literature oscillating around the complex relationship between the movement undertaken and its impact on the microbiome.","PeriodicalId":18329,"journal":{"name":"Medical Journal of Cell Biology","volume":"10 1","pages":"138 - 143"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42907811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract In science and medicine, terminology is a precise system of terms that are generally accepted in a given discipline. In anatomy, it is important to distinguish between terminology and nomenclature, which is an officially accepted set of terms arranged according to certain rules and principles. The Terminologia Anatomica (1998) has been the golden standard in the field of terminology, even though it contains minor errors, inaccuracies, discrepancies, multiplication of terms, inconvenient terms as well as synonyms and identical names for different structures. All of these problems need to be solved in the future, which is a key cchallenge in the field. Another major challenge is to create a clear, precise, logical, flawless and worldwide accepted list of anatomical terms that would cover all the names that are used in education and clinical practice. Many researchers and clinicians assert that this task is still ahead of us. The aim of this article is to explain why the longstanding tradition of medical terminology should be respected and why major and rapid changes should never be endorsed. Anatomical terminology, if correctly used, is a basic tool of communication both within and outside the field. It is also a guide through the intricacies of the human anatomy.
{"title":"Anatomical and medical terminology: new challenges and perspectives","authors":"Piotr Paweł Chmielewski","doi":"10.2478/acb-2022-0016","DOIUrl":"https://doi.org/10.2478/acb-2022-0016","url":null,"abstract":"Abstract In science and medicine, terminology is a precise system of terms that are generally accepted in a given discipline. In anatomy, it is important to distinguish between terminology and nomenclature, which is an officially accepted set of terms arranged according to certain rules and principles. The Terminologia Anatomica (1998) has been the golden standard in the field of terminology, even though it contains minor errors, inaccuracies, discrepancies, multiplication of terms, inconvenient terms as well as synonyms and identical names for different structures. All of these problems need to be solved in the future, which is a key cchallenge in the field. Another major challenge is to create a clear, precise, logical, flawless and worldwide accepted list of anatomical terms that would cover all the names that are used in education and clinical practice. Many researchers and clinicians assert that this task is still ahead of us. The aim of this article is to explain why the longstanding tradition of medical terminology should be respected and why major and rapid changes should never be endorsed. Anatomical terminology, if correctly used, is a basic tool of communication both within and outside the field. It is also a guide through the intricacies of the human anatomy.","PeriodicalId":18329,"journal":{"name":"Medical Journal of Cell Biology","volume":"10 1","pages":"102 - 107"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48362990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Health problems related to pelvic floor muscles, as faecal incontinence (FI), urinary incontinence (UI) and constipation have a significant negative impact on a person’s life. The disease is accompanied by a serious symptoms, which exclude the patient from the local community. It is noteworthy that FI and UI involve increased financial outlays for the treatment of these disorders. Definition of the faecal incontinence is an uncontrolled passage of faecal materials that has occurred at least two to four times within four weeks of the last six months. Anatomy of pelvic fundus is strictly corelated with those diseases, because ability to contract and relax the muscles of the pelvic floor helps with the body’s daily basic functions. Risk factors of FI/UI include age, gender, comorbidities such as diabetes and irritable bowel syndrome, and obstetric factors. It could be treated with physiotherapy, pharmacotherapy or invasive treatment. A review of the literature indicates that the problem of FI/UI is a significant clinical issue of concern to clinicians due to very limited treatment techniques. There is a lack of primary research covering this issue in the world literature. The authors of this paper therefore believe that a holistic view of the subject based on the latest scientific data is necessary.
{"title":"Pelvic floor muscle morphology and its impact on urinary incontinence and faecal incontinence","authors":"Ivanna Lazarchuk, Bartosz Barzak, Slawomir Wozniak","doi":"10.2478/acb-2022-0018","DOIUrl":"https://doi.org/10.2478/acb-2022-0018","url":null,"abstract":"Abstract Health problems related to pelvic floor muscles, as faecal incontinence (FI), urinary incontinence (UI) and constipation have a significant negative impact on a person’s life. The disease is accompanied by a serious symptoms, which exclude the patient from the local community. It is noteworthy that FI and UI involve increased financial outlays for the treatment of these disorders. Definition of the faecal incontinence is an uncontrolled passage of faecal materials that has occurred at least two to four times within four weeks of the last six months. Anatomy of pelvic fundus is strictly corelated with those diseases, because ability to contract and relax the muscles of the pelvic floor helps with the body’s daily basic functions. Risk factors of FI/UI include age, gender, comorbidities such as diabetes and irritable bowel syndrome, and obstetric factors. It could be treated with physiotherapy, pharmacotherapy or invasive treatment. A review of the literature indicates that the problem of FI/UI is a significant clinical issue of concern to clinicians due to very limited treatment techniques. There is a lack of primary research covering this issue in the world literature. The authors of this paper therefore believe that a holistic view of the subject based on the latest scientific data is necessary.","PeriodicalId":18329,"journal":{"name":"Medical Journal of Cell Biology","volume":"10 1","pages":"118 - 123"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45780586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The aim of this study was to explore temporal and spatial variability of the frequency of the ABO and Rhesus blood group phenotypes in Polish donors from Lower Silesia between 1946 and 1990. Data on 158,134 individuals (113,714 men and 44,420 women) were obtained from two databases containing information about blood donors from Lower Silesia. The rate and direction of changes in the frequency of the blood groups were evaluated with regression analysis and Pearson’s correlation coefficient. Significant differences in the frequencies were found for the analysed period. The largest differences were observed for A and O blood groups. A significant increase in the frequency of the A group and a decrease in the O group were noted. The incidence of the AB group in both sexes did not change significantly. However, an insignificant decreasing trend in the frequency of the AB group in men was observed. An opposite and significant trend for this blood type was found in women. For the B group, the increase was significant in both sexes but it was greater in men. A significant increase in the frequency of the Rh(+) factor was noted. These results suggest that there were minor differences in the frequencies of ABO and Rh blood groups between the counties. This study demonstrated microevolutionary changes, thereby contributing new information to the field. These findings can be useful for the management of blood banks and the interpretation of microevolutionary changes.
{"title":"Changes in the frequency of ABO and Rh blood group phenotypes in Polish donors from Lower Silesia","authors":"Piotr Paweł Chmielewski","doi":"10.2478/acb-2022-0017","DOIUrl":"https://doi.org/10.2478/acb-2022-0017","url":null,"abstract":"Abstract The aim of this study was to explore temporal and spatial variability of the frequency of the ABO and Rhesus blood group phenotypes in Polish donors from Lower Silesia between 1946 and 1990. Data on 158,134 individuals (113,714 men and 44,420 women) were obtained from two databases containing information about blood donors from Lower Silesia. The rate and direction of changes in the frequency of the blood groups were evaluated with regression analysis and Pearson’s correlation coefficient. Significant differences in the frequencies were found for the analysed period. The largest differences were observed for A and O blood groups. A significant increase in the frequency of the A group and a decrease in the O group were noted. The incidence of the AB group in both sexes did not change significantly. However, an insignificant decreasing trend in the frequency of the AB group in men was observed. An opposite and significant trend for this blood type was found in women. For the B group, the increase was significant in both sexes but it was greater in men. A significant increase in the frequency of the Rh(+) factor was noted. These results suggest that there were minor differences in the frequencies of ABO and Rh blood groups between the counties. This study demonstrated microevolutionary changes, thereby contributing new information to the field. These findings can be useful for the management of blood banks and the interpretation of microevolutionary changes.","PeriodicalId":18329,"journal":{"name":"Medical Journal of Cell Biology","volume":"10 1","pages":"108 - 117"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44733113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Body height is positively correlated with overall health and survival. Previous studies have found that taller people are healthier and live longer than their smaller counterparts. Despite numerous investigations, the correlation between adult stature and longevity remains uncertain. The objective of the present study is to evaluate the relationship between adult height and lifespan. Data were available from 480493 men and 364666 women who died in the years 2004-2008 in Poland. Pearson’s r coefficients of correlation were calculated and ANOVA was employed. The correlation between height and longevity was negative and statistically significant in men (r = –0.27, p < 0.0001) and women (r = –0.25, p < 0.0001). However, after allowing for the cohort effect, these correlations proved to be very weak and significant. On balance, these results do not corroborate the hypothesis that taller people live longer, and the effects of body height on survival were small. In this article, these findings are discussed in an attempt to identify the biological mechanisms that are responsible for greater longevity in short people. This paper also deals with several biological factors and mechanisms involved in the link between body size and longevity.
{"title":"Do taller people live longer? Evaluating the relationship between adult stature and longevity","authors":"Piotr Paweł Chmielewski","doi":"10.2478/acb-2022-0025","DOIUrl":"https://doi.org/10.2478/acb-2022-0025","url":null,"abstract":"Abstract Body height is positively correlated with overall health and survival. Previous studies have found that taller people are healthier and live longer than their smaller counterparts. Despite numerous investigations, the correlation between adult stature and longevity remains uncertain. The objective of the present study is to evaluate the relationship between adult height and lifespan. Data were available from 480493 men and 364666 women who died in the years 2004-2008 in Poland. Pearson’s r coefficients of correlation were calculated and ANOVA was employed. The correlation between height and longevity was negative and statistically significant in men (r = –0.27, p < 0.0001) and women (r = –0.25, p < 0.0001). However, after allowing for the cohort effect, these correlations proved to be very weak and significant. On balance, these results do not corroborate the hypothesis that taller people live longer, and the effects of body height on survival were small. In this article, these findings are discussed in an attempt to identify the biological mechanisms that are responsible for greater longevity in short people. This paper also deals with several biological factors and mechanisms involved in the link between body size and longevity.","PeriodicalId":18329,"journal":{"name":"Medical Journal of Cell Biology","volume":"10 1","pages":"176 - 183"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48777471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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