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Significance of Inflammatory Markers; C-reactive Protein, Hyperuricemia, and Albuminuria in type 2 Diabetes Patients 2 型糖尿病患者的炎症指标、C 反应蛋白、高尿酸血症和白蛋白尿的意义
Pub Date : 2024-01-09 DOI: 10.48036/apims.v13i4.997
A. Pak, Inst Med Sci, J. Karmani, Arif Mumtaz, Syed Asim, Ali Shah, Rifat Yasmin, Wajahat Sultan Baig, T. Kazmi
Objective:  To determine the significance of inflammatory markers, including C-reactive protein, hyperuricemia, and albuminuria, in individuals with type 2 diabetes. Methodology: This cross-sectional analytical study was done at Diabetic Clinic and Nephrology Department of Akbar Niazi Teaching Hospital, Islamabad between Jan 2023 and July 2023. Total 150 consecutive patients aged between 35 and 60 years with type 2 diabetes were enrolled in study. Participants were divided in two groups on the basis of C-reactive protein and uric acid levels. Group-A comprised individuals with type 2 diabetes and C-reactive protein levels, while Group-B included individuals with type 2 diabetes and uric acid levels. Every patient underwent necessary clinical and laboratory assessments. The measurement of C-reactive protein was conducted through a particle-enhanced immunoturbidimetric assay. Results: The study population demonstrates an average age of 49.41±7.66 years. In linear regression analysis, both C-reactive protein and uric acid emerged as independently predictor the albumin to creatinine ratio include (?=0.20, 95% CI 0.1-0.30, and p=0.001 for C-reactive protein, and ?=0.20, 95% CI 0.1-0.30, and p=0.001 for uric acid). In logistic regression, the albuminuria odd for C-reactive protein and uric acid groups was 4.05 (95% CI 2.60-9.15, p=0.001). Conclusion: In individuals with type 2 diabetes, there was an association observed between albuminuria and heightened levels of C-reactive protein and elevated uric acid levels. Additionally, there was an interactive effect on albuminuria observed between C-reactive protein and uric acid.  
目的 确定炎症指标(包括 C 反应蛋白、高尿酸血症和白蛋白尿)在 2 型糖尿病患者中的重要性。研究方法:这项横断面分析研究于 2023 年 1 月至 2023 年 7 月期间在伊斯兰堡 Akbar Niazi 教学医院的糖尿病诊所和肾病科进行。共有 150 名年龄在 35 岁至 60 岁之间的 2 型糖尿病患者参加了研究。根据 C 反应蛋白和尿酸水平将参与者分为两组。A 组为 C 反应蛋白水平正常的 2 型糖尿病患者,B 组为尿酸水平正常的 2 型糖尿病患者。每位患者都接受了必要的临床和实验室评估。C 反应蛋白的测量是通过粒子增强免疫比浊法进行的。研究结果研究对象的平均年龄为(49.41±7.66)岁。在线性回归分析中,C-反应蛋白和尿酸均可独立预测白蛋白与肌酐的比值(C-反应蛋白=0.20,95% CI 0.1-0.30,P=0.001;尿酸=0.20,95% CI 0.1-0.30,P=0.001)。在逻辑回归中,C 反应蛋白组和尿酸组的白蛋白尿奇数为 4.05(95% CI 2.60-9.15,p=0.001)。结论在 2 型糖尿病患者中,白蛋白尿与 C 反应蛋白水平升高和尿酸水平升高之间存在关联。此外,还观察到 C 反应蛋白和尿酸之间对白蛋白尿的交互影响。
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引用次数: 0
Continuous Versus Interrupted Sutures for Repair of Episiotomy or Second-Degree Perineal Tears 连续缝合与间断缝合修复外阴切开术或二度会阴撕裂术
Pub Date : 2023-09-07 DOI: 10.48036/apims.v19i3.823
A. Pak, Inst Med Sci, Uzma Nayyer, Mariam Tariq, Afnan Rizwan, Gul Amber, Muhammad Nahyan Dar, Michelle Ahmad Jaspal
Objective: To compare the efficacy in absorbed continuous vs interrupted suture material for repair the episiotomy and 2nd degree perineal tears in terms of time required for repair, number of suture material used and pain relief following childbirth. Methodology: A comparative randomized controlled trial was performed in Gynae & Obstetrics department of Akbar Niazi Teaching Hospital, Islamabad between May and October 2022. Total 300 patients of term delivered by spontaneous vaginal birth with episiotomy or 2nd degree perineal tear through non probability consecutive sampling were included. In Group A perineal tear was repaired with continuous non locking sutures and in Group B continuous locking sutures was done. Duration of procedures and number of suture material used was noted. Patients were followed for 24 hours for pain. Results: The patients mean age was 24.85±3.98 years. The gestational mean age at time of delivery of all the cases was 38.79±0.84 weeks. Type of perineal trauma among all the cases was observed as 84 (28.0%) cases had 2nd degree perineal tear while 216 (72.0%) had episiotomy. Mean time required for suture repair in Group A was 9.0±0.86 sec, while in Group B, the mean time required for suture repair was 15.02±2.06 sec (p-value = 0.001). Mean suture material required for suture repair in Group A was 108.38±9.70 cm, while in Group B, the mean suture material required for suture repair was 114.01±7.17 cm (p-value = 0.001). The mean pain score in Group A was calculated as 3.64±0.94 on VAS, while in Group mean pain was 5.46+0.75 on VAS (p-value = 0.001). Conclusion: Through this study, it was proved that episiotomy and repair of perineal tears with continuous suture is faster, and uses less suture material without increasing complexity compared to interrupted suture. The continuous suture method of perineal repair is associated with less pain than the interrupted method.
目的从修复所需的时间、使用的缝合材料数量和分娩后疼痛缓解的角度,比较吸收连续缝合材料与间断缝合材料修复会阴切开术和二度会阴撕裂的疗效。方法:2022 年 5 月至 10 月期间,在伊斯兰堡阿克巴尔-尼亚齐教学医院妇产科进行了一项随机对照比较试验。通过非概率连续抽样,共纳入了 300 名经阴道自然分娩、外阴切开术或二度会阴撕裂的足月产妇。在 A 组中,会阴撕裂采用连续非锁定缝合修复;在 B 组中,采用连续锁定缝合修复。手术时间和使用的缝合材料数量均有记录。对患者进行 24 小时疼痛随访。结果患者平均年龄为(24.85±3.98)岁。所有病例分娩时的平均孕周为 38.79±0.84 周。所有病例的会阴创伤类型为 84 例(28.0%)会阴二度撕裂,216 例(72.0%)会阴切开。A 组缝合修复所需的平均时间为(9.0±0.86)秒,而 B 组缝合修复所需的平均时间为(15.02±2.06)秒(P 值 = 0.001)。A 组缝合修复所需的平均缝合材料为 108.38±9.70 厘米,而 B 组缝合修复所需的平均缝合材料为 114.01±7.17 厘米(P 值 = 0.001)。经计算,A 组的平均疼痛评分为(3.64±0.94)分,而 B 组的平均疼痛评分为(5.46+0.75)分(P 值 = 0.001)。结论本研究证明,与间断缝合法相比,采用连续缝合法进行会阴切开术和会阴撕裂修补术速度更快,使用的缝合材料更少,且不会增加复杂性。会阴修复的连续缝合法比间断缝合法疼痛更少。
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引用次数: 0
Inculcation of Professionalism in House Officers Through Mentoring by Senior Residents; A Pilot Project in Obstetrics & Gynecology 通过资深住院医师的指导向住院医师灌输专业精神;妇产科试点项目
Pub Date : 2023-09-07 DOI: 10.48036/apims.v19i3.917
A. Pak, Inst Med Sci, Iram Sarwar
Objectives: To evaluate the effectiveness of mentoring of house officers on their transition towards their professional life, preparation for the workplace, and improving their learning through standardized training and assessment during their rotation in Obstetrics & Gynecology. Methodology: The project mixed method study was implemented in Gynae C Unit of Ayub Teaching Hospital, Abbottabad from 1st May 2022 to 31st May 2022. A mentorship program was initiated as a one-month pilot project to train house officers of Obstetrics & Gynecology and inculcate professional values and practices relevant to the discipline. Thereafter, a mixed method study was conducted to evaluate the program having qualitative semi structured interviews from mentors and mentees as well as quantitative formative assessment. Results: House officers appreciated the program for acquiring knowledge and overcoming difficulties at work, as well as relieving stress and anxiety and suggested formal training of mentors. Mentors said that the program helped to develop their leadership and communication skills. Conclusion: Mentoring had a positive effect on house officers learning and overall satisfaction despite some challenges and limitations.
目的评估在妇产科轮转期间,通过标准化培训和评估,对住院医师进行指导对其职业生活过渡、职场准备和提高学习效率的效果。 研究方法:该混合方法研究项目于 2022 年 5 月 1 日至 2022 年 5 月 31 日在阿伯塔巴德阿尤布教学医院妇科 C 室实施。作为为期一个月的试点项目,启动了一项导师计划,以培训妇产科住院医师,并灌输与该学科相关的专业价值观和实践。此后,通过对导师和被指导者进行定性半结构式访谈以及定量形成性评估,开展了一项混合方法研究,以评估该计划。 研究结果:舍监对该计划在获取知识、克服工作困难、缓解压力和焦虑方面的作用表示赞赏,并建议对导师进行正规培训。辅导员表示,该计划有助于培养他们的领导能力和沟通技巧。 结论尽管存在一些挑战和局限性,但导师制对舍监的学习和总体满意度产生了积极影响。
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引用次数: 0
Assessment of Microbial Diversity Pattern of Sensitivity and Antimicrobial Susceptibility in Patients Admitted with Urosepsis 尿毒症患者的微生物敏感性和抗菌药敏感性多样性模式评估
Pub Date : 2023-09-07 DOI: 10.48036/apims.v19i3.924
A. Pak, Inst Med Sci, Khalid Shahab, Ahmad Zuhayr Mufti, Mohammad Areeb Iqbal, Munayal Roghani, Farhan Zeb, Umair Amin, Dr. Ahmad Zuhayr Mufti
Objectives: To determine the spectrum of bacteria causing urosepsis and antibiotic sensitivity patterns among admitted patients with a clear diagnosis of urosepsis. Methodology: A cross-sectional study was conducted in General Medicine OPDs at the Hayatabad Medical Complex, Peshawar from January 2022 to December 2022. Data was collected prospectively. We included a total of 800 patients with a confirmed diagnosis of urosepsis, the diagnosis was confirmed using >5 pus cells per HPF as a cut-off value. Samples were sent for culture sensitivity testing in the microbiology lab and after identification of the causative bacteria, the sensitivities to a spectrum of antibiotics were assessed. Results: Out of the 800 enrolled patients, samples of 664 patients grew colonies, mostly comprised of Gram-negative ones. The gender distribution showed (54.70%) females as compared to (45.30%) males, with an age range of 18 -70 years. The species grown primarily is E. Coli 57.5%, Providencia Sp. 9.3%, Enterococcus faecium 7.5%, Enterobacter 7.5%, Klebsiella 2.4%, and a mixed growth pattern in 9.0% of samples. The sensitivity percentage for E. coli against Meropenem was 99.5%, Imipenem 99.6%, Colistin 99.9%, Polymyxin-B 99.9%, Fosfomycin 96.4%, Amikacin 96.7%, Gentamicin 97.4%, Nitrofurantoin 91.5%, Ceftriaxone 34.4%, Ciprofloxacin 31.5%, Piperacillin/Tazobactam 10.2%, Cefepime 39.1%, Co-Amoxiclav 19.0%, Ceftazidime 37.4% and Cefoperazone /Sulbactam 26.5%.  Conclusion: The spectrum of bacteria sensitivity showed high sensitivity towards Meropenem, Imipenem, Colistin, Polymyxin-B, Amikacin, and Gentamicin; medium sensitivity to Fosfomycin and Nitrofurantoin; and low sensitivity against Ceftriaxone, Ciprofloxacin, Piperacillin/Tazobactam, Cefepime, Co-Amoxiclav, Ceftazidime, and Cefoperazone /Sulbactam among patients with urosepsis.
目的确定明确诊断为尿道炎的入院患者中引起尿道炎的细菌谱和抗生素敏感性模式。 研究方法:于 2022 年 1 月至 2022 年 12 月在白沙瓦哈亚塔巴德医疗中心的全科门诊部进行了一项横断面研究。数据收集为前瞻性。我们共纳入了 800 名确诊为尿道炎的患者,确诊以每 HPF >5 个脓细胞为临界值。样本送至微生物实验室进行培养敏感性检测,在确定致病菌后,对一系列抗生素的敏感性进行评估。 结果在 800 名登记的患者中,有 664 名患者的样本长出了菌落,其中大部分是革兰氏阴性菌。性别分布显示,女性占 54.70%,男性占 45.30%,年龄在 18-70 岁之间。生长的菌种主要是大肠杆菌(E. Coli)57.5%、普罗维登西亚菌(Providencia Sp.9.3%,粪肠球菌 7.5%,肠杆菌 7.5%,克雷伯氏菌 2.4%,9.0%的样本呈混合生长模式。大肠杆菌对美罗培南的敏感率为 99.5%,对亚胺培南的敏感率为 99.6%,对秋水仙素的敏感率为 99.9%,对多粘菌素-B 的敏感率为 99.9%,对磷霉素的敏感率为 96.4%,对阿米卡星的敏感率为 96.7%,对庆大霉素的敏感率为 97.4%、硝基呋喃妥因 91.5%、头孢曲松 34.4%、环丙沙星 31.5%、哌拉西林/他唑巴坦 10.2%、头孢吡肟 39.1%、氯阿莫西林 19.0%、头孢唑肟 37.4%和头孢哌酮/舒巴坦 26.5%。 结论细菌敏感性谱显示,尿道炎患者对美罗培南、亚胺培南、考利星、多粘菌素-B、阿米卡星和庆大霉素高度敏感;对磷霉素和硝基呋喃妥因中等敏感;对头孢曲松、环丙沙星、哌拉西林/他唑巴坦、头孢吡肟、氯阿莫西林、头孢嗪肟和头孢哌酮/舒巴坦低度敏感。
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引用次数: 0
Effectiveness of Cataract Uncomplicated Surgery on Retina Thickness 白内障无并发症手术对视网膜厚度的影响
Pub Date : 2023-09-07 DOI: 10.48036/apims.v19i3.796
Anum Badar, Amena Masrur, Sidra Naseem, Rabeeah Zafar, Sarah Naveed Malik, Tahira Afzal Khan
Background: The most common preventable cause is cataract for the loss of vision, and pseudophakic cystoid macular edema, also called Irvine-Gass syndrome, is a well-known complication after cataract surgery. Objective: To determine changes in total retinal thickness after cataract uncomplicated surgery. Objective: To determine changes in total retinal thickness after cataract uncomplicated surgery. Methodology: A prospective quasi experimental study was done at the department of Ophthalmology of Combined Military Hospital (CMH), Rawalakot AJK between September and December 2022. Total 28 patients (28 eyes) who underwent phacoemulsification uncomplicated surgery and grafting of intraocular lens in unilateral eye were included. The effective phacoemulsification time and total energy used during phacoemulsification cataract surgery was noted. The optical coherence tomography (OCT) scan was performed to analyze the retina thickness. Data were collected preoperatively, which serves as a baseline measurement. This baseline measurement was used to compare with measurements taken at postoperative day 1, end of week 1, end of month 1, and follow-up period month 3 to assess changes in various parameters such as total retinal thickness. Results: The patient’s mean age comprising of 20 (71.4%) males and 8 (28.6%) females was 54.73±7.6 years. Typically, there is a transient decrease in retinal thickness, immediately after surgery (day 1), followed by a gradual increase in thickness over the weeks (first week) and months (1st & 3rd month) following surgery. Overall, a positive correlation was seen between phacoemulsification time, total energy, and changes in the retinal thickness (1mm & 1-3mm grids) (p ? 0.05). Conclusion: The study concluded that a follow-up period of at least 3 months is generally recommended after surgery of cataract to assess the whether preoperative levels return of total retina. Methods: A prospective quasi experimental study was done at the department of Ophthalmology of Combined Military Hospital (CMH), Rawalakot AJK between September and December 2022. Total 28 patients (28 eyes) who underwent phacoemulsification uncomplicated surgery and grafting of intraocular lens in unilateral eye were included. The effective phacoemulsification time and total energy used during phacoemulsification cataract surgery was noted. The optical coherence tomography (OCT) scan was performed to analyze the retina thickness. Data were collected preoperatively, which serves as a baseline measurement. This baseline measurement was used to compare with measurements taken at postoperative day 1, end of week 1, end of month 1, and follow-up period month 3 to assess changes in various parameters such as total retinal thickness. Results: The patient’s mean age comprising of 20 (71.4%) males and 8 (28.6%) females was 54.73±7.6 years. Typically, there is a transient decrease in retinal thickness, immediately after surgery (day 1), followed by a gradual increase
背景:白内障是导致视力丧失的最常见的可预防原因,而假性囊样黄斑水肿(又称 Irvine-Gass 综合征)是白内障手术后的一种众所周知的并发症。目标:确定视网膜总厚度的变化确定白内障无并发症手术后视网膜总厚度的变化。目的:确定白内障无并发症手术后视网膜总厚度的变化:确定白内障无并发症手术后视网膜总厚度的变化。方法:前瞻性准实验2022 年 9 月至 12 月期间,在 Rawalakot AJK 的联合军事医院(Combined Military Hospital,CMH)眼科进行了一项前瞻性准实验研究。共有 28 名患者(28 只眼)接受了无并发症的乳化手术,并在单眼中移植了眼内晶状体。研究人员记录了白内障超声乳化手术的有效乳化时间和使用的总能量。进行光学相干断层扫描(OCT)以分析视网膜厚度。术前收集的数据可作为基线测量值。基线测量值与术后第 1 天、第 1 周末、第 1 月末和随访第 3 个月的测量值进行比较,以评估视网膜总厚度等各种参数的变化。结果患者的平均年龄为 54.73±7.6 岁,其中男性 20 人(71.4%),女性 8 人(28.6%)。通常情况下,手术后视网膜厚度会立即(第 1 天)出现短暂的下降,然后在手术后的几周(第 1 周)和几个月(第 1 和第 3 个月)内逐渐增加。总体而言,乳化时间、总能量和视网膜厚度变化(1 毫米和 1-3 毫米网格)之间呈正相关(P ?)结论:研究认为,一般建议在白内障手术后进行至少 3 个月的随访,以评估总视网膜是否恢复到术前水平。研究方法2022 年 9 月至 12 月期间,在 Rawalakot AJK 的联合军事医院(Combined Military Hospital,CMH)眼科进行了一项前瞻性准实验研究。共有 28 名患者(28 只眼)接受了无并发症的乳化手术,并在单眼中移植了眼内晶状体。研究人员记录了白内障超声乳化手术的有效乳化时间和使用的总能量。进行光学相干断层扫描(OCT)以分析视网膜厚度。术前收集的数据可作为基线测量值。基线测量值与术后第 1 天、第 1 周末、第 1 月末和随访第 3 个月的测量值进行比较,以评估视网膜总厚度等各种参数的变化。结果:患者的平均年龄为 54.73±7.6 岁,其中男性 20 人(71.4%),女性 8 人(28.6%)。通常情况下,手术后视网膜厚度会立即(第 1 天)出现短暂的下降,然后在手术后的几周(第 1 周)和几个月(第 1 和第 3 个月)内逐渐增加。总体而言,乳化时间、总能量和视网膜厚度变化(1毫米和1-3毫米网格)之间呈正相关(p§‰¤ 0.05)。结论研究认为,白内障手术后一般建议至少随访3个月,以评估视网膜总厚度是否恢复到术前水平。
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引用次数: 0
The Fetomaternal Outcome of Induction of Labour in Idiopathic Oligohydramnios 特发性少血畸形引产的母胎结局
Pub Date : 2023-09-07 DOI: 10.48036/apims.v19i3.927
A. Pak, Inst Med Sci, Kinza Alam, Afnan Rizwan, Amarta Imdad Hussain, Sahar Farooq, Taqdees Iftikhar, Mehreen Mehdi
Objective: To assess fetomaternal outcome of induction of labour in patients with idiopathic oligohydramnios at ANTH to reduce the morbidity associated with increased cesarean section rate and deliver alive healthy babies. Methodology: This quasi experimental study was conducted in the department of Obstetrics & Gynecology, Alsuffah hospital Rawalpindi and Akbar Niazi Teaching Hospital, Islamabad, over a period of six months from June to Dec 2022. A detailed history was taken followed by a thorough general physical examination and obstetric examination. Routine investigations were performed along with obstetrical ultrasonography. CTG was performed and after ensuring a reactive trace along with no contraindication to vaginal delivery; were offered option of induction of labour after informed consent on predesigned consent form with tab. prostin E2 3mg maximum of two doses with 6 hours apart via vaginal route as per induction of labour protocol at 37 weeks or beyond and were followed-up in OPD till postnatal follow up after 1 week. Results: The mean age of the patients was 26.85 ± 0.46 years. Majority 30 (41.1%) of the patients had parity of 3 or more and most 31 (42.47%) of the females in the study were given induction of labor at 39 weeks’ gestation followed by 27 (36.99%) were given IOL at 38 weeks. The mean value of the amniotic fluid index was 4.35 ± 1.84. Main bulk 34 (46.58%) of the females delivered with cesarean section and most common indication for cesarean section Pathological CTG in 15 (20.55%) patients. Mean birth weight was recorded to be 3.25 ± 0.86 kg and about one third of the babies, 24 (32.88%) babies required admission in NICU. A large number 31 (42.47%) of the children had low APGAR score (< 7) at 5 minutes. Conclusions: The development of foetal distress, meconium-stained liquor, caesarean delivery rates, NICU admission rates, and low birth weight are all linked to pregnancies with isolated oligohydramnios.
目的评估在 ANTH 对特发性少尿症患者进行引产的胎儿和产妇结局,以降低与剖宫产率增加相关的发病率,并接生健康的活产婴儿。 研究方法:这项准实验研究于 2022 年 6 月至 12 月在拉瓦尔品第 Alsuffah 医院和伊斯兰堡 Akbar Niazi 教学医院妇产科进行,为期六个月。在详细询问病史后,进行了全面的体格检查和产科检查。进行了常规检查和产科超声波检查。根据引产方案,在 37 周或 37 周以上时,在事先设计好的同意书上填写知情同意后,可选择通过阴道途径引产,剂量为前列腺素 E2 3 毫克,最多两次,每次间隔 6 小时。 结果患者的平均年龄为(26.85 ± 0.46)岁。大多数 30 名(41.1%)患者的胎次为 3 或以上,31 名(42.47%)女性患者在妊娠 39 周时接受了引产,27 名(36.99%)患者在妊娠 38 周时接受了 IOL。羊水指数的平均值为(4.35 ± 1.84)。大部分 34 名(46.58%)产妇采用剖宫产,其中 15 名(20.55%)产妇的剖宫产最常见原因是病理 CTG。平均出生体重为 3.25 ± 0.86 千克,约三分之一的婴儿(24 名,占 32.88%)需要入住新生儿重症监护室。有31名婴儿(42.47%)在5分钟内的APGAR评分较低(小于7分)。 结论胎儿窘迫、胎粪染色液、剖腹产率、新生儿重症监护室入院率和低出生体重都与孤立性少水胎儿有关。
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引用次数: 0
Comparison of Efficacy of Single Oral Dose Fluconazole Versus Single Oral Dose Itraconazole in Patients with Pityriasis Versicolor 单次口服氟康唑与单次口服伊曲康唑对鳞屑性皮肤病患者的疗效比较
Pub Date : 2023-09-07 DOI: 10.48036/apims.v19i3.816
A. Pak, Inst Med Sci, Aleena Nasir, Abdul Haseeb Khan, Ayesha Rizwan, Najia Sajjad, Sara Sarwar
Objective: To compare the efficacy of single oral dose Fluconazole and Itraconazole in patients with Pityriasis Versicolor. Methodology: This Randomized control trial study was conducted at the Department of Dermatology, Combined Military Hospital, Abbottabad, Pakistan from March 2022 to August 2022. A total of 60 patients coming to OPD of derma department and diagnosed with Tinea Versicolor were randomized in 2 equal groups of 30 patients each. Patients diagnosed on odd serial number were allocated to group A and were prescribed oral Fluconazole (400 mg stat) while patients diagnosed on even serial number were allocated to group B and were prescribed oral Itraconazole (1000 mg stat). Diagnosis was made clinically and then by using mycological tests. Follow up visits were made at completion of 2nd and 4th weeks of start of treatment. Primary outcome was set as efficacy of the treatments at completion of 4 weeks that was assessed using mycological tests. Results:  In this study, age ranged was from 19 to 40 years with mean age of 30.066±7.74 years. Mean duration of disease was 4.216±1.29 months. At completion of study (4 weeks), treatment was effective in 25 patients (83.33%) in group A while in 17 patients (56.6%) in group B with a significant difference in efficacy between two groups (p=0.024). There was a good tolerability in both groups without any serious adverse reactions reported.  Conclusion: Single oral dose of Fluconazole is more effective compared to single oral dose of Itraconazole in the treatment of Pityriasis Versicolor.
目的比较单次口服氟康唑和伊曲康唑对脓疱疮患者的疗效。研究方法这项随机对照试验研究于 2022 年 3 月至 2022 年 8 月在巴基斯坦阿伯塔巴德联合军事医院皮肤科进行。在皮肤科门诊就诊并确诊为癣病的 60 名患者被随机分为两组,每组 30 人。诊断为奇数序号的患者被分配到 A 组,处方为口服氟康唑(400 毫克,静滴);诊断为偶数序号的患者被分配到 B 组,处方为口服伊曲康唑(1000 毫克,静滴)。通过临床诊断,然后进行真菌学检测。在开始治疗后的第 2 周和第 4 周进行随访。主要结果设定为治疗 4 周后的疗效,并通过真菌学检测进行评估。研究结果 本研究中,患者年龄在 19-40 岁之间,平均年龄为(30.066±7.74)岁。平均病程为(4.216±1.29)个月。研究结束时(4 周),A 组 25 名患者(83.33%)治疗有效,B 组 17 名患者(56.6%)治疗有效,两组疗效差异显著(P=0.024)。两组患者均有良好的耐受性,无任何严重不良反应报告。 结论与伊曲康唑单次口服剂量相比,氟康唑单次口服剂量治疗脓疱疮效果更好。
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引用次数: 0
Geographic Accessibility of Burn Care Centres; A Battle of Life in Pakistan 烧伤护理中心的地理可达性;巴基斯坦的一场生命之战
Pub Date : 2023-09-07 DOI: 10.48036/apims.v19i3.874
Muhammad Rehan, Tariq Iqbal, Esha Kamran
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引用次数: 0
Barriers to Uptake of Postpartum Long Acting Reversible Contraception; A Cross Sectional Study 产后服用长效可逆避孕药的障碍;一项横断面研究
Pub Date : 2023-09-07 DOI: 10.48036/apims.v19i3.850
A. Pak, Inst Med Sci, Imran Sohail Sheikh, G. Nasir, Hameed Mumtaz Durrani, Haroon Rashid Khan, Jawairiah Liaqat
Objective: To investigate factors limiting postpartum long-acting reversible contraception from being used in our system.   Methodology: This cross sectional study was carried out in the department of Obstetrics and Gynecology, Nishtar Medical University, Multan, from September 2022 to April 2023, consisted of all women who gave birth at this hospital during the study period. Data were gathered using a structured questionnaire that had been pretested. The survey asks questions about sociodemographics, reproductive health, healthcare, knowledge and attitudes about LARC, and family planning use. At discharge, a skilled nurse conducted a face-to-face interview with the patient in a quiet private room to gather the data.  Results: In our study most (56.04%) of the women were between age of 26-35 years and (69.97%) belonged to urban area. Main bulk (47.68%) of the women had parity of 3-4 and majority (44.58%) of the women in sample had 0-2 alive children and (21.05%) women presented with history of previous abortion. Most (74.61%) of the women had spontaneous vaginal delivery. The rate of use of LARCs was 69 (21.36%) in our study sample. The comparison of rate of use of LARC’s was found to be significantly (P-value < 0.05) associated with increasing age, increasing women education, occupation and job status. Family income, number of alive children and duration for plan to have next pregnancy were also significant (P-value < 0.05) contributors for uptake of LARCs. Conclusion: The rate of used of postpartum LARC was low (21.36%) in the studied population. Postpartum women from of higher age, having higher education, with formal employment, having higher level of family income, and with higher duration for plan to have next pregnancy were more likely to use LARC.
目的调查限制我们系统使用产后长效可逆避孕药的因素。 研究方法:这项横断面研究于 2022 年 9 月至 2023 年 4 月在木尔坦市尼什塔尔医科大学妇产科进行,研究对象包括研究期间在该医院分娩的所有产妇。数据是通过一份经过预先测试的结构化问卷收集的。调查内容包括社会人口统计学、生殖健康、医疗保健、对 LARC 的认识和态度以及计划生育的使用情况。出院时,一名熟练的护士在一个安静的私人房间与患者进行了面对面的访谈,以收集数据。 研究结果在我们的研究中,大多数(56.04%)妇女的年龄在 26-35 岁之间,(69.97%)属于城市地区。大部分(47.68%)妇女的胎次为 3-4 次,样本中大多数(44.58%)妇女有 0-2 个存活的孩子,(21.05%)妇女曾有过流产史。大多数妇女(74.61%)经阴道自然分娩。在我们的研究样本中,LARCs 的使用率为 69(21.36%)。研究发现,LARC 使用率的比较与年龄的增长、妇女受教育程度的提高、职业和工作状况有明显的关系(P 值<0.05)。家庭收入、存活子女数和计划下次怀孕的时间也是使用 LARCs 的重要因素(P 值小于 0.05)。结论在研究人群中,产后 LARC 的使用率较低(21.36%)。年龄越大、受教育程度越高、有正式工作、家庭收入水平越高、计划下次怀孕时间越长的产后妇女越有可能使用 LARC。
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引用次数: 0
Intraoperative Wound Irrigation for Prevention of Surgical Site Infections After Abdominal Surgery 术中伤口冲洗预防腹部手术后的手术部位感染
Pub Date : 2023-09-07 DOI: 10.48036/apims.v19i3.912
A. Pak, Inst Med Sci, Maryam Hameed, Muhammad Nazim Khan, Irmaghana Basharat, Fahad Mudassar Hameed, U. Ghani, Nauman Anwar, Dr. Muhammad Nazim Khan, Khan Hameed M
Objectives: To compare the frequency of surgical site infections after abdominal surgery with and without intraoperative irrigation of the surgical wounds. Methodology: This randomized controlled trial was performed in general surgery department, PAF Hospital, Islamabad from 10th August 2022 to 9th May 2023. A total of 520 patients undergoing abdominal surgeries of any gender between the ages of 15–70 years were included. Patients were randomly divided in two groups on the basis of non-probability, consecutive sampling. The participants included in the group-A did not receive any intraoperative wound irrigation. The participants in the Group-B received intraoperative wound irrigation with antiseptic solution i.e., povidone-iodine in solution. Each patient was followed up respectively on 7th, 21st and 30th days postoperatively to observe surgical site infection. Chi square test was applied to compare SSI percentage between two groups. P-value of less than 0.05 was taken as significant. Results: Mean age was 39.87±6.93 years in group-A and 37.67±7.56 years in Group-B. Out of 520 patients, 344 (66.15%) were males and 176 (33.85%) were females. Surgical site infection after abdominal surgery without intraoperative irrigation was found to be 34 (13.08%) and surgical site infection after abdominal surgery with intraoperative irrigation was 12 (4.62%), hence statistically significant (p-value = 0.0007). Conclusion: This study concluded that intraoperative wound irrigation is effective to prevent the surgical site infections after abdominal surgery.
目的比较腹部手术后对手术伤口进行术中冲洗和不进行术中冲洗的手术部位感染频率。 方法:随机对照试验这项随机对照试验于 2022 年 8 月 10 日至 2023 年 5 月 9 日在伊斯兰堡 PAF 医院普外科进行。共纳入了 520 名接受腹部手术的患者,年龄在 15-70 岁之间,性别不限。根据非概率连续抽样法将患者随机分为两组。A 组患者不接受任何术中伤口冲洗。B 组患者术中使用聚维酮碘消毒液进行伤口冲洗。分别在术后第 7 天、第 21 天和第 30 天对每位患者进行随访,观察手术部位感染情况。采用卡方检验比较两组患者的 SSI 百分比。P 值小于 0.05 为显著。 结果A 组平均年龄(39.87±6.93)岁,B 组平均年龄(37.67±7.56)岁。520 例患者中,男性 344 例(66.15%),女性 176 例(33.85%)。未进行术中冲洗的腹部手术后手术部位感染为 34 例(13.08%),进行术中冲洗的腹部手术后手术部位感染为 12 例(4.62%),因此具有统计学意义(P 值 = 0.0007)。 结论本研究认为,术中伤口冲洗可有效预防腹部手术后的手术部位感染。
{"title":"Intraoperative Wound Irrigation for Prevention of Surgical Site Infections After Abdominal Surgery","authors":"A. Pak, Inst Med Sci, Maryam Hameed, Muhammad Nazim Khan, Irmaghana Basharat, Fahad Mudassar Hameed, U. Ghani, Nauman Anwar, Dr. Muhammad Nazim Khan, Khan Hameed M","doi":"10.48036/apims.v19i3.912","DOIUrl":"https://doi.org/10.48036/apims.v19i3.912","url":null,"abstract":"Objectives: To compare the frequency of surgical site infections after abdominal surgery with and without intraoperative irrigation of the surgical wounds. Methodology: This randomized controlled trial was performed in general surgery department, PAF Hospital, Islamabad from 10th August 2022 to 9th May 2023. A total of 520 patients undergoing abdominal surgeries of any gender between the ages of 15–70 years were included. Patients were randomly divided in two groups on the basis of non-probability, consecutive sampling. The participants included in the group-A did not receive any intraoperative wound irrigation. The participants in the Group-B received intraoperative wound irrigation with antiseptic solution i.e., povidone-iodine in solution. Each patient was followed up respectively on 7th, 21st and 30th days postoperatively to observe surgical site infection. Chi square test was applied to compare SSI percentage between two groups. P-value of less than 0.05 was taken as significant. Results: Mean age was 39.87±6.93 years in group-A and 37.67±7.56 years in Group-B. Out of 520 patients, 344 (66.15%) were males and 176 (33.85%) were females. Surgical site infection after abdominal surgery without intraoperative irrigation was found to be 34 (13.08%) and surgical site infection after abdominal surgery with intraoperative irrigation was 12 (4.62%), hence statistically significant (p-value = 0.0007). Conclusion: This study concluded that intraoperative wound irrigation is effective to prevent the surgical site infections after abdominal surgery.","PeriodicalId":184398,"journal":{"name":"Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139342028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University
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