Pub Date : 2024-10-01Epub Date: 2020-07-20DOI: 10.23736/S0026-4806.20.06681-1
Wenting Zou, Ying Li, Ziheng Xue
{"title":"Analysis of the effect of lower limb nursing on prevention of deep venous thrombosis in long-term bedridden patients.","authors":"Wenting Zou, Ying Li, Ziheng Xue","doi":"10.23736/S0026-4806.20.06681-1","DOIUrl":"10.23736/S0026-4806.20.06681-1","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38178731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01Epub Date: 2020-06-22DOI: 10.23736/S0026-4806.20.06753-1
Lili Guo, Cuiling Mu, Ting Yang, Defen Yin
{"title":"Effect of whole-course seamless link nursing model intervention on the treatment of acute coronary syndrome.","authors":"Lili Guo, Cuiling Mu, Ting Yang, Defen Yin","doi":"10.23736/S0026-4806.20.06753-1","DOIUrl":"10.23736/S0026-4806.20.06753-1","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38074619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01Epub Date: 2020-07-21DOI: 10.23736/S0026-4806.20.06752-X
Honglei Shi, Bin Xu, Min Yang
{"title":"NF-κB signaling pathway promotes proliferation and inhibits apoptosis of childhood acute lymphoblastic leukemia cells via regulating CRIM1.","authors":"Honglei Shi, Bin Xu, Min Yang","doi":"10.23736/S0026-4806.20.06752-X","DOIUrl":"10.23736/S0026-4806.20.06752-X","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38182377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: This study aimed to investigate the expression and prognostic significance of topoisomeraseII (Topo-II) and c-erbB-2.
Methods: A total of 92 cases of patients with breast cancer who came to our hospital for treatment from November 2013 to January 2016 were included as the experimental group, and 90 healthy subjects who came to our hospital for physical examination during the same period were selected as the control group. ELISA was used to detect the expression levels of Topo-II and c-erbB-2 in serum of each group. The correlation among expression levels, degree of tumor differentiation and pathological types of Topo-II and c-erbB-2 in serum of patients with breast cancer were observed.
Results: The expression levels of Topo-II and c-erbB-2 in the experimental group were higher than those in the control group (P<0.05). The expression levels of Topo-II and c-erbB-2 in serum of patients with different stages increased with the clinical stages. The survival rate of patients with different expression levels of Topo-II and c-erbB-2 was compared, it was found that the survival rate of the low-expression group (80.49%) was significantly higher than that of the high-expression group (50.98%). The ROC curve was used to analyze Topo-II and c-erbB-2, the result showed that the sensitivity, specificity and AUC of Topo-II in the diagnosis of breast cancer was 72.22%, 94.56% and 0.8641, respectively. The sensitivity, specificity, and AUC of c-erbB-2 in the diagnosis of breast cancer were 94.45%, 66.30% and 0.8379, respectively.
Conclusions: In conclusion, Topo-II and c-erbB-2 are highly expressed in breast cancer and are closely related to breast cancer. Moreover, the detection of Topo-II and c-erbB-2 in serum can help diagnose gestational diabetes mellitus quickly and effectively.
{"title":"The expression and prognostic significance of Topo-II and c-erbB-2 in breast cancer.","authors":"Hua Shao, Chuanbo Feng, Zhonglin Wang, Shuangjiu Zhu, Xinwen Zheng","doi":"10.23736/S0026-4806.20.06637-9","DOIUrl":"10.23736/S0026-4806.20.06637-9","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the expression and prognostic significance of topoisomeraseII (Topo-II) and c-erbB-2.</p><p><strong>Methods: </strong>A total of 92 cases of patients with breast cancer who came to our hospital for treatment from November 2013 to January 2016 were included as the experimental group, and 90 healthy subjects who came to our hospital for physical examination during the same period were selected as the control group. ELISA was used to detect the expression levels of Topo-II and c-erbB-2 in serum of each group. The correlation among expression levels, degree of tumor differentiation and pathological types of Topo-II and c-erbB-2 in serum of patients with breast cancer were observed.</p><p><strong>Results: </strong>The expression levels of Topo-II and c-erbB-2 in the experimental group were higher than those in the control group (P<0.05). The expression levels of Topo-II and c-erbB-2 in serum of patients with different stages increased with the clinical stages. The survival rate of patients with different expression levels of Topo-II and c-erbB-2 was compared, it was found that the survival rate of the low-expression group (80.49%) was significantly higher than that of the high-expression group (50.98%). The ROC curve was used to analyze Topo-II and c-erbB-2, the result showed that the sensitivity, specificity and AUC of Topo-II in the diagnosis of breast cancer was 72.22%, 94.56% and 0.8641, respectively. The sensitivity, specificity, and AUC of c-erbB-2 in the diagnosis of breast cancer were 94.45%, 66.30% and 0.8379, respectively.</p><p><strong>Conclusions: </strong>In conclusion, Topo-II and c-erbB-2 are highly expressed in breast cancer and are closely related to breast cancer. Moreover, the detection of Topo-II and c-erbB-2 in serum can help diagnose gestational diabetes mellitus quickly and effectively.</p>","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38169260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2023-01-12DOI: 10.23736/S0026-4806.22.08479-8
Quan Shi, Jianhui Chen, Yafa Yu
{"title":"Efficacy analysis of Wenxin granule combined with metoprolol tartrate in the treatment of elderly patients with arrhythmia.","authors":"Quan Shi, Jianhui Chen, Yafa Yu","doi":"10.23736/S0026-4806.22.08479-8","DOIUrl":"10.23736/S0026-4806.22.08479-8","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10871215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2021-09-20DOI: 10.23736/S0026-4806.21.07725-9
Guidong Xu, Cui Li, Cong Liu
{"title":"Analysis of clinical effect of closed reduction and percutaneous Kirschner wire internal fixation in the treatment of supracondylar fracture of humerus in children.","authors":"Guidong Xu, Cui Li, Cong Liu","doi":"10.23736/S0026-4806.21.07725-9","DOIUrl":"10.23736/S0026-4806.21.07725-9","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39432792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-08-01DOI: 10.23736/S0026-4806.23.08748-7
Xiaoyan Lei, Yuandi Cheng, Li Fang, Jialin Zhu, Mei Wang, Wei Zuo
{"title":"Clinical application of detailed nursing in perioperative period of neonatal thoracoscopic esophageal atresia repair.","authors":"Xiaoyan Lei, Yuandi Cheng, Li Fang, Jialin Zhu, Mei Wang, Wei Zuo","doi":"10.23736/S0026-4806.23.08748-7","DOIUrl":"10.23736/S0026-4806.23.08748-7","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9908824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-06-29DOI: 10.23736/S0026-4806.23.08749-9
Fangfang Yuan, Huijun Chen, Fang Li, Weidong Zhao, Shunyi Song
{"title":"Analysis on effect and influencing factors of precision rehabilitation therapy on scales of ABC, CARS, CHAT and CABS in children with autism spectrum disorder.","authors":"Fangfang Yuan, Huijun Chen, Fang Li, Weidong Zhao, Shunyi Song","doi":"10.23736/S0026-4806.23.08749-9","DOIUrl":"10.23736/S0026-4806.23.08749-9","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9749724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-06-13DOI: 10.23736/S0026-4806.23.08688-3
Yanhua Zhang, Xiaoli Wang, Yilin Li, Bo Liu, Da Zhao, Yan Yu, Bo Li, Lili Bao, Wenjiao Ye, Jun Li, Wenhui Zhang
{"title":"AFAP1-AS1 promotes the proliferation, migration and invasion of endometrial stromal cells from endometriosis through regulating the PI3K/AKT pathway.","authors":"Yanhua Zhang, Xiaoli Wang, Yilin Li, Bo Liu, Da Zhao, Yan Yu, Bo Li, Lili Bao, Wenjiao Ye, Jun Li, Wenhui Zhang","doi":"10.23736/S0026-4806.23.08688-3","DOIUrl":"10.23736/S0026-4806.23.08688-3","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9994590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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