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Minerva medica最新文献

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An analysis of the current situation of China's model of combining medical care with nursing care under the background of the internet plus. 互联网+背景下中国医养结合模式现状分析
IF 4.7 4区 医学 0 MEDICINE, GENERAL & INTERNAL
Minerva medica
Pub Date : 2025-12-01 Epub Date: 2023-07-18 DOI: 10.23736/S0026-4806.23.08793-1
Huaiying Shi, Yichen Zhang, Xing Wang, Lijun Wu, Xun Gong, Hongwei Xiong, Xuanxuan Wang
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引用次数: 0
Positive effect of individualized grading nursing on blood coagulation function in children with Henoch-Schonlein purpura nephritis. 个体化分级护理对海诺氏紫癜肾炎患儿凝血功能的积极影响
IF 4.7 4区 医学 0 MEDICINE, GENERAL & INTERNAL
Minerva medica
Pub Date : 2025-08-01 Epub Date: 2020-09-03 DOI: 10.23736/S0026-4806.20.06906-2
Hongmei Ma, Mengyi Yuan, Hua Zhu
{"title":"Positive effect of individualized grading nursing on blood coagulation function in children with Henoch-Schonlein purpura nephritis.","authors":"Hongmei Ma, Mengyi Yuan, Hua Zhu","doi":"10.23736/S0026-4806.20.06906-2","DOIUrl":"10.23736/S0026-4806.20.06906-2","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":" ","pages":"359-360"},"PeriodicalIF":4.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38339861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zercepac® plus capecitabine for intracranial lesions in a patient with HER2-positive converted from triple-negative breast cancer. Zercepac®加卡培他滨治疗一名HER2阳性三阴性乳腺癌患者的颅内病变。
IF 4.7 4区 医学 0 MEDICINE, GENERAL & INTERNAL
Minerva medica
Pub Date : 2025-08-01 Epub Date: 2022-07-05 DOI: 10.23736/S0026-4806.22.08240-4
Gang Li, Xuelian Li, Mei Yang
{"title":"Zercepac® plus capecitabine for intracranial lesions in a patient with HER2-positive converted from triple-negative breast cancer.","authors":"Gang Li, Xuelian Li, Mei Yang","doi":"10.23736/S0026-4806.22.08240-4","DOIUrl":"10.23736/S0026-4806.22.08240-4","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":" ","pages":"362-363"},"PeriodicalIF":4.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40469892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations of expressions of serum miR-124 and miR-182 with endothelial function and inflammation level in patients with cerebral arteriosclerosis. 脑动脉硬化患者血清 MiR-124 和 MiR-182 的表达与内皮功能和炎症水平的关系
IF 4.7 4区 医学 0 MEDICINE, GENERAL & INTERNAL
Minerva medica
Pub Date : 2025-06-01 Epub Date: 2020-12-02 DOI: 10.23736/S0026-4806.20.07161-X
Lixiu Han, Rui Wang, Na Li
{"title":"Associations of expressions of serum miR-124 and miR-182 with endothelial function and inflammation level in patients with cerebral arteriosclerosis.","authors":"Lixiu Han, Rui Wang, Na Li","doi":"10.23736/S0026-4806.20.07161-X","DOIUrl":"10.23736/S0026-4806.20.07161-X","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":" ","pages":"281-283"},"PeriodicalIF":4.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38326462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of rehabilitation physiotherapy intervention on life quality of patients with sequelae of stroke. 康复理疗干预对中风后遗症患者生活质量的影响。
IF 4.7 4区 医学 0 MEDICINE, GENERAL & INTERNAL
Minerva medica
Pub Date : 2025-06-01 Epub Date: 2020-09-03 DOI: 10.23736/S0026-4806.20.06908-6
Changwei Yang, Dai Zhao, Guangling Ba
{"title":"Effect of rehabilitation physiotherapy intervention on life quality of patients with sequelae of stroke.","authors":"Changwei Yang, Dai Zhao, Guangling Ba","doi":"10.23736/S0026-4806.20.06908-6","DOIUrl":"10.23736/S0026-4806.20.06908-6","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":" ","pages":"280-281"},"PeriodicalIF":4.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38339862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive markers associated to fibrotic evolution in hypersensitivity pneumonitis: a single institution's analysis. 与超敏性肺炎纤维化演变相关的预测标志物：单一机构的分析。
IF 4.7 4区 医学 0 MEDICINE, GENERAL & INTERNAL
Minerva medica
Pub Date : 2025-02-01 Epub Date: 2023-09-15 DOI: 10.23736/S0026-4806.23.08823-7
Francesco R Bertuccio, Valerio Partenope, Davide Piloni, Simone Montini, Nicola Baio, Chandra Bortolotto, Adele Valentini, Angelo G Corsico, Giulia M Stella
{"title":"Predictive markers associated to fibrotic evolution in hypersensitivity pneumonitis: a single institution's analysis.","authors":"Francesco R Bertuccio, Valerio Partenope, Davide Piloni, Simone Montini, Nicola Baio, Chandra Bortolotto, Adele Valentini, Angelo G Corsico, Giulia M Stella","doi":"10.23736/S0026-4806.23.08823-7","DOIUrl":"10.23736/S0026-4806.23.08823-7","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":" ","pages":"79-81"},"PeriodicalIF":4.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10592210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the effect of targeted nursing in patients with endocrine disorders and obesity. 对内分泌失调和肥胖症患者进行针对性护理的效果分析。
IF 4.7 4区 医学 0 MEDICINE, GENERAL & INTERNAL
Minerva medica
Pub Date : 2025-02-01 Epub Date: 2020-07-28 DOI: 10.23736/S0026-4806.20.06844-5
Hong Xin, Hongxia Shao, Hongyan Deng
{"title":"Analysis of the effect of targeted nursing in patients with endocrine disorders and obesity.","authors":"Hong Xin, Hongxia Shao, Hongyan Deng","doi":"10.23736/S0026-4806.20.06844-5","DOIUrl":"10.23736/S0026-4806.20.06844-5","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":" ","pages":"84-86"},"PeriodicalIF":4.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38207329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed treatment with endostatin displays a protective role against pulmonary hypertension by targeting VEGF pathway. 通过靶向血管内皮生长因子通路，内司他丁延迟治疗对肺动脉高压具有保护作用。
IF 4.7 4区 医学 0 MEDICINE, GENERAL & INTERNAL
Minerva medica
Pub Date : 2025-02-01 Epub Date: 2021-04-29 DOI: 10.23736/S0026-4806.21.07145-7
Shuai Huang, Nannan Li, Dong Yan

Background: Endostatin (ES) is an endogenous angiogenesis inhibitor. It is confirmed that ES has antitumor effects and plays a crucial part in regulating vascular smooth cells' proliferation. However, ES's effect on pulmonary hypertension (PH) is unclear. The aim of this study was to determine the effect of ES on PH's pathogenesis.

Methods: PH was induced by pneumonectomy plus monocrotaline (MCT) injection, as indicated with significantly increased pulmonary arterial pressure and vascular wall thickness.

Results: Immunohistochemical analysis showed that under physiological conditions, ES localized in endothelial cells (ECs) and spread to the muscular vascular layers in PH rats. ES was transfected into the lungs of rats intratracheally 2 weeks after MCT injection. Consequently, ES not only reduced elevated VEGF's expression but also reversed pulmonary artery remodeling. Eventually, ES improved elevated right ventricular (RV) mean pressure and RV hypertrophy.

Conclusions: The administration of ES may be a new treatment for PH and PA remodeling, associating with the downregulation of VEGF production.

背景：内ostatin（ES）是一种内源性血管生成抑制剂。已证实 ES 具有抗肿瘤作用，并在调节血管平滑细胞增殖方面发挥重要作用。然而，ES对肺动脉高压（PH）的影响尚不明确。我们的目的是确定 ES 对 PH 发病机制的影响：方法：通过肺切除术加注射单克隆肾上腺素（MCT）诱发肺动脉高压，肺动脉压和血管壁厚度明显增加：免疫组化分析表明，在生理条件下，ES定位于PH大鼠的内皮细胞（EC），并扩散到肌肉血管层。在注射 MCT 2 周后，将 ES 经气管内转染至大鼠肺部。结果，ES 不仅降低了血管内皮生长因子的表达，还逆转了肺动脉重塑。最终，ES 改善了右心室（RV）平均压升高和 RV 肥厚：结论：服用 ES 可能是治疗 PH 和 PA 重塑的一种新方法，它与血管内皮生长因子分泌的下调有关。
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引用次数: 0
Efficacy and safety of pars plana vitrectomy combined with internal limiting membrane peeling for macular hollow retinal detachment. 玻璃体旁切除术联合内缘膜剥离治疗黄斑空洞性视网膜脱离的有效性和安全性。
IF 4.7 4区 医学 0 MEDICINE, GENERAL & INTERNAL
Minerva medica
Pub Date : 2025-02-01 Epub Date: 2020-09-03 DOI: 10.23736/S0026-4806.20.06841-X
Jinwei Ren, Min Liu, Linlin Wang, Mingtao Zhao
{"title":"Efficacy and safety of pars plana vitrectomy combined with internal limiting membrane peeling for macular hollow retinal detachment.","authors":"Jinwei Ren, Min Liu, Linlin Wang, Mingtao Zhao","doi":"10.23736/S0026-4806.20.06841-X","DOIUrl":"10.23736/S0026-4806.20.06841-X","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":" ","pages":"83-84"},"PeriodicalIF":4.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38339859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-dose corticosteroids adjusted to oxygen requirement and monitoring of serum C-reactive protein to improve outcome of non-critically ill COVID-19 patients: the CocAA-CoLa Plus Study. 根据需氧量调整大剂量皮质类固醇并监测血清c反应蛋白以改善非危重症COVID-19患者的预后：可口可乐+研究
IF 4.7 4区 医学 0 MEDICINE, GENERAL & INTERNAL
Minerva medica
Pub Date : 2025-02-01 Epub Date: 2023-05-11 DOI: 10.23736/S0026-4806.22.08326-4
Jean-Philippe Kevorkian, Claire Vandiedonck, Jean Laganier, Amanda Lopes, Ruxandra Burlacu, Florine Feron, Marie-Laure Chai X, Damien Sene, Jean-Pierre Riveline, Jean-François Gautier, Bruno Megarbane
{"title":"High-dose corticosteroids adjusted to oxygen requirement and monitoring of serum C-reactive protein to improve outcome of non-critically ill COVID-19 patients: the CocAA-CoLa Plus Study.","authors":"Jean-Philippe Kevorkian, Claire Vandiedonck, Jean Laganier, Amanda Lopes, Ruxandra Burlacu, Florine Feron, Marie-Laure Chai X, Damien Sene, Jean-Pierre Riveline, Jean-François Gautier, Bruno Megarbane","doi":"10.23736/S0026-4806.22.08326-4","DOIUrl":"10.23736/S0026-4806.22.08326-4","url":null,"abstract":"","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":" ","pages":"75-79"},"PeriodicalIF":4.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9436905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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