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Bibliometric Indices and its Role for the Quality Assessment of the Authors Published Content in the Scientific Journals 文献计量指标及其在科技期刊作者发表内容质量评价中的作用
Pub Date : 1900-01-01 DOI: 10.5455/ijbh.2021.9.244-253
I. Masic
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引用次数: 4
On Occasion of the 10th Anniversary of the Academy of Medical Sciences of Bosnia and Herzegovina 在波斯尼亚和黑塞哥维那医学科学院成立十周年之际
Pub Date : 1900-01-01 DOI: 10.5455/ijbh.2019.7.114-115
M. Zildžić
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引用次数: 0
Evaluation of Hematological Parameters After ESWL and Ureterorenoscopy for the Treatment of Kidney Stones ESWL和输尿管镜治疗肾结石后血液学参数的评价
Pub Date : 1900-01-01 DOI: 10.5455/ijbh.2023.29-34
J. Prstojevic, M. Hasanbegovic, V. Mišanović, Almira Lujinović, Azra Metović, J. Mušanović, J. Alić
Background: Bleeding and hematuria can be a consequence of both ESWL and URS treatment.Changes in hematological parameters may be indicative of bleeding events.Objective: The aim of the present study was to explore the hematological parameters after ESWL and ureterorenoscopy for the treatment of kidney stones. Methods: A prospective study included patients (120) with verified ureterolithiasis <10 mm in the upper half of the proximal third of the ureter. Patients were divided into two groups using the random sample method for the application of active stone removal methods ESWL or URS with contact disintegration.Patients were evaluated with routine hematological, biochemical blood parameters, and non-contrast enhanced computed abdominal tomography (CT) before the procedure.Routine laboratory analyzes were performed using standard methods and included determination of the number of erythrocytes, platelets, hemoglobin, hematocrit, glucose, INR, APTTwhich were measured preintervention, the first postoperative day and six months after the intervention. Results: The preintervention hemoglobin value in patients with urolithiasis treated with URS treatment was 140 g/L (136.2–155.7), and was statistically significantly higher compared to the measurement on the first post-intervention day [137.5 g/L (127, 2–156.7) (p<0,05)], as well as in relation to the measurement after six months [139 g/L (134.2–151.7), (p<0,05).The pre-interventional hematocrit value in patients with urolithiasis treated with URS treatment was 0.42 (0.41–0.47), but it dropped statistically significantly on the measurement on the first post-intervention day to a value of 0.41 (0.38–0, 47) (p=0.003). The hematocrit value after six months was 0.44 (0.41–0.47) and was statistically significantly higher compared to the pre-intervention measurement (p=0.002), as well as compared to the measurement on the first post-intervention day (p< 0.001). The pre-intervention INR value in patients with urolithiasis treated with URS treatment was 0.90 (0.86–1.1), and on the first post-intervention day, it increased statistically significantly to a value of 0.99 (0.89–1.1), (p=0.005).The INR value after six months continued to grow to a value of 1.02 (0.96–1.2), which was statistically significantly higher compared to the INR value measured on the first post-intervention day (p<0.001), as and in relation to the INR value measured before the intervention (p=0.007).Conclusion: The results of this study, in terms of hematological parameters, showed more favorable outcomes in patients treated with ESWL compared to URS lithotripsy. Significantly lower hemoglobin values six months after URS treatment, as well as a decrease in the number of platelets on the first postoperative day, lead to the conclusion that URS lithotripsy, which represents a more aggressive method compared to ESWL, may have less favorable consequences for patients.
背景:出血和血尿可能是ESWL和尿路治疗的结果。血液学参数的变化可能是出血事件的指示。目的:探讨体外冲击波碎石联合输尿管镜治疗肾结石后的血液学参数。方法:一项前瞻性研究纳入了输尿管近三分之一上部小于10毫米的输尿管结石患者(120例)。采用随机抽样法将患者分为两组,分别采用主动取石方法ESWL或尿路尿路合并接触性崩解。术前对患者进行常规血液学、血液生化参数和非增强腹部计算机断层扫描(CT)评估。采用标准方法进行常规实验室分析,包括测定干预前、术后第一天和干预后6个月的红细胞、血小板、血红蛋白、红细胞压积、葡萄糖、INR、apt的数量。结果:尿石症患者经URS治疗后干预前血红蛋白值为140 g/L(136.2 ~ 155.7),高于干预后第1天的137.5 g/L (127.2 ~ 156.7) (p< 0.05),高于6个月后的139 g/L(134.2 ~ 151.7),差异有统计学意义(p< 0.05)。尿石症患者行URS治疗时,介入前红细胞压积值为0.42(0.41 - 0.47),干预后第1天测量时,红细胞压积值为0.41(0.38 - 0.47),差异有统计学意义(p=0.003)。6个月后的红细胞压积值为0.44(0.41-0.47),与干预前比较(p=0.002),与干预后第1天比较(p< 0.001),差异有统计学意义。尿石症患者经URS治疗后干预前INR值为0.90(0.86-1.1),干预后第1天INR值上升至0.99(0.89-1.1),差异有统计学意义(p=0.005)。6个月后的INR值继续增长至1.02(0.96-1.2),与干预后第一天测量的INR值相比(p<0.001),与干预前测量的INR值相比(p=0.007),有统计学意义上的显著提高(p<0.001)。结论:本研究结果显示,在血液学参数方面,ESWL治疗患者比URS碎石治疗更有利。尿路碎石治疗6个月后血红蛋白值明显降低,术后第一天血小板数量减少,这表明尿路碎石比ESWL更积极,但对患者的影响可能更差。
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引用次数: 0
The Most Influential Scientists in the Development of Public Health: Geoffrey Rose (1926-1993) 对公共卫生发展最有影响的科学家:杰弗里·罗斯(1926-1993)
Pub Date : 1900-01-01 DOI: 10.5455/ijbh.2022.10.65-66
Dženan Jahić
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引用次数: 0
Altered Vaginal pH Value and Enterobacteria as a Risk Factor in the Development of Precancerous Lesions of the Cervix 阴道pH值改变和肠杆菌是子宫颈癌前病变发展的危险因素
Pub Date : 1900-01-01 DOI: 10.5455/ijbh.2022.10.102-105
A. Barakovic, Mahira Jahić, A. Cerovac, A. Hadžimehmedović
Background: Vaginal microflora plays an important role in cervical carcinogenesis. An increase in vaginal pH is associated with the severity of squamous intraepithelial lesion (SIL) and a decrease in the number of lactobacilli. Microbial dysbiosis contributes to the damage of the epithelial barrier, as well as the reprogramming of immune and metabolic signaling. Dysbiotic bacteria cause damage to the epithelial barrier, immune dysregulation and genotoxicity and create a tumor-permissive microenvironment. Objective: The aim of this study was to determine the presence of risk factors (abnormal colposcopic and microbiological status, elevated pH of the vaginal environment) in regular Pap tests and LSIL. Methods: Retrospective prospective study 2021-2022. 90 women with pap smears were analyzed: 40 with LSIL at the Gynecological Center “Dr. Mahira Jahić” Tuzla and 50 with normal findings at the Tesanj Health Center. General data such as: age of the subjects, reproductive status, contraception, smoking and data on colposcopic examination, microbiological findings and vaginal pH value were analyzed. Statistical data processing was done in the SPSS program. Results: The average age of the test subjects is 39.94, in normal Pap 41.20 years, and in LSIL 38.38 years. The vital characteristics of the subjects did not differ significantly, except for smoking, where in LSIL findings, they consumed cigarettes significantly more often. Abnormal colposcopic examination were found in 85% (N-34) of women with LSIL. In subjects with LSIL, a positive microbiological test for enterobacteria was found in 47.5% (N-19) and a normal pap test in 12% (N-6). Statistically significant difference p=0.00523 p<0.05, E faecalis and E coli had the highest prevalence in LSIL. The mean pH value of the vaginal environment in LSIL is 5.38, and 4.96 in a regular pap test. Subjects with LSIL in 10% (N-4) had a normal pH test, and 48% (N-24) had a normal Pap test. P=0.00129 p < (0.05). A normal pH value was significantly more common in subjects with a normal Pap test. Microbiological flora, especially enterogenic bacteria, are more common in LSIL than in women with a regular pap test. Conclusion: when monitoring women with LSIL, special attention should be paid to the elimination of present enterobacteria (E.faecalis and E.coli) as a possible risk factor in the development of precancerous lesions (SIL) and cervical cancer.
背景:阴道菌群在宫颈癌发生中起重要作用。阴道pH值的升高与鳞状上皮内病变(SIL)的严重程度和乳酸菌数量的减少有关。微生物生态失调有助于上皮屏障的损伤,以及免疫和代谢信号的重编程。益生菌导致上皮屏障损伤、免疫失调和遗传毒性,并创造肿瘤容许的微环境。目的:本研究的目的是确定在常规巴氏试验和LSIL中存在的危险因素(阴道镜和微生物状态异常,阴道环境pH升高)。方法:2021-2022年回顾性前瞻性研究。对90名接受子宫颈抹片检查的妇女进行了分析:40名在图兹拉妇科中心“Mahira jahiki博士”患有LSIL, 50名在特桑吉健康中心检查结果正常。分析研究对象的年龄、生育状况、避孕、吸烟等一般资料,以及阴道镜检查、微生物学检查和阴道pH值等资料。统计数据处理在SPSS软件中完成。结果:受试者平均年龄39.94岁,正常Pap组平均年龄41.20岁,低sil组平均年龄38.38岁。受试者的重要特征没有显著差异,除了吸烟,在LSIL研究结果中,他们吸烟的频率明显更高。阴道镜检查异常的女性占85% (N-34)。在LSIL患者中,肠道菌群检测阳性的占47.5% (N-19),巴氏试验正常的占12% (N-6)。差异有统计学意义p=0.00523 p<0.05,粪肠杆菌和大肠杆菌在LSIL中患病率最高。LSIL患者阴道环境的平均pH值为5.38,常规巴氏试验为4.96。10% (N-4) LSIL患者pH试验正常,48% (N-24) Pap试验正常。P=0.00129 P <(0.05)。正常的pH值在巴氏试验正常的受试者中更为常见。微生物菌群,特别是肠源性细菌,在LSIL中比在常规巴氏涂片检查的妇女中更常见。结论:在监测LSIL妇女时,应特别注意消除存在的肠杆菌(粪肠杆菌和大肠杆菌),这是癌前病变(SIL)和宫颈癌发展的可能危险因素。
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引用次数: 0
Introducing the Textbook "Pharmacology and Toxicology Manual", 6th Edition 介绍教材《药理学与毒理学手册》第六版
Pub Date : 1900-01-01 DOI: 10.5455/ijbh.2021.9.135-135
L. Žunić
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引用次数: 0
The Most Influential Scientists in the Development of Biomedicine: Carlos Juan Finlay (1833-1915) 对生物医学发展最有影响的科学家:卡洛斯·胡安·芬利(1833-1915)
Pub Date : 1900-01-01 DOI: 10.5455/IJBH.2020.8.144-144
I. Masic
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引用次数: 0
Economic Aspect of Managing Health Services 管理卫生服务的经济方面
Pub Date : 1900-01-01 DOI: 10.5455/ijbh.2022.10.70-70
I. Masic
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引用次数: 0
Cognition and Health-related Quality of Life in Multiple Sclerosis 多发性硬化症患者的认知与健康相关生活质量
Pub Date : 1900-01-01 DOI: 10.5455/ijbh.2023.11.212-215
S. Hajrić, Dzenita Besirovic, G. Sulejmanpasić, Nermina Bajramagic, A. Serdarević
Background: Cognitive dysfunctions are considered as a poor prognostic factor that influence health-related quality of life in multiple sclerosis. Objective: The aim of the study was to evaluate the impact of cognitive impairment on the quality of life in multiple sclerosis patients. Methods: This study included 60 MS patients treated at the Department of Neurology, Clinical Center University of Sarajevo. Inclusion criteria were clinically definite diagnosis of multiple sclerosis, 18 years of age or older and were able to give written informed consent. Cognitivefunction was evaluated by the Montreal Cognitive Assessment (MoCa) screening test. Quality of life was evaluated by SF36 questionnaire. Results: 88.33% of patients had cognitive impairment with 68.33% with mild cognitive impairment. Abstraction (60,83%), language (56,66%), executive functions (53.66%) and delayed recall (28.33%) were rated the worst. The median value of SF-36 score was 54.1 (27.7-70.01). The lowest results were achieved in the QOL domains of psycial limitation with a median value of 12.5 (0-75) and emotional limitation 33.3 (0-100). It is found statistically significant correlation of the MoCa score with social functioning, energy, vitality and general health (p<0.05) and physical functioning (p<0.001) domains of quality of life, as well as with SF -36 total scores (p<0.05). Among group of patients with cognitive impairment, statistically significant positive correlation between cognitive status mental health HRQOL domain (rho=0.427; p<0.001) was found. Conclusion: Cognitive impairment is very often presented in patients with multiple sclerosis with significant contribution to a poorer quality of life. It is associated with physical and emotional limitations, as well as poorer mental health. Further studies are needed, especially when we take into account very important clinical and prognostic role of cognition in multiple sclerosis.
背景:认知功能障碍被认为是影响多发性硬化症患者健康相关生活质量的不良预后因素。目的:本研究的目的是评估认知障碍对多发性硬化症患者生活质量的影响。方法:本研究纳入在萨拉热窝大学临床中心神经内科治疗的60例多发性硬化症患者。纳入标准为临床明确诊断为多发性硬化症,年龄在18岁及以上,并能够给予书面知情同意。认知功能通过蒙特利尔认知评估(MoCa)筛查测试进行评估。采用SF36问卷评估患者的生活质量。结果:88.33%的患者存在认知障碍,其中轻度认知障碍占68.33%。其中,抽象(60,83%)、语言(56,66%)、执行功能(53.66%)和延迟回忆(28.33%)被评为最差。SF-36评分中位数为54.1(27.7-70.01)。在生活质量方面,心理限制的中位数为12.5(0-75),情绪限制的中位数为33.3(0-100)。MoCa评分与生活质量的社会功能、能量、活力和一般健康(p<0.05)和身体功能(p<0.001)以及SF -36总分(p<0.05)有统计学意义。在认知障碍组患者中,认知状态与心理健康HRQOL域呈正相关有统计学意义(rho=0.427;P <0.001)。结论:认知障碍在多发性硬化症患者中非常常见,对生活质量较差有重要影响。它与身体和情感上的限制以及较差的心理健康有关。需要进一步的研究,特别是当我们考虑到认知在多发性硬化症中非常重要的临床和预后作用时。
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引用次数: 0
In Opportunity Losses for Non-COVID-19 Patients Due to Restricted Access Healthcare 非covid -19患者因获得医疗服务受限而遭受的机会损失
Pub Date : 1900-01-01 DOI: 10.5455/ijbh.2021.9.294/295
S. Jankovic
letter, would like to draw attention to the necessity of investing in extensive epidemiological and pharmacoeconomic research on the benefits and harms (costs) of interventions and measures taken in the fight against the COVID 19 pandemic, so that rational decisions can be made in close future.
信中,我想提请大家注意,有必要投资于广泛的流行病学和药物经济学研究,研究在抗击COVID - 19大流行中采取的干预措施和措施的利弊(成本),以便在不久的将来做出理性决策。
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引用次数: 0
期刊
International Journal on Biomedicine and Healthcare
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