Pub Date : 2020-08-31DOI: 10.15587/1729-4061.2020.210750
O. Pihnastyi, D. Yemelianova, D. Lysytsia
Two classes of models for describing production flow lines are analyzed. The use of models of these classes for the design of highly efficient control systems of production lines, the technological route of which consists of a large number of technological operations, is analyzed. The division of the technological route into a large number of operations is caused by the development trend of modern production lines. Synchronization of production line equipment performance is provided by an accumulating buffer. A formalized description of the production line was used as a foundation for constructing equations for each models class. The common features of using each models class in the description of production systems, as well as the conditions for their application, are shown. The form of the system dynamics model and PDE model equations is substantiated. The assumption about a deterministic rate of processing parts and the absence of a time delay and feedback between the parameters of technological operations was made when deriving the equations. The use of generalized technological operations in the system dynamics model as a way to reduce the number of model equations is discussed. Two limiting transitions from the PDE model equations to the system dynamics equations are demonstrated. It is shown that the system dynamics equations are a special case of the PDE model equations, the result of the aggregation of production line parameters within the technological operation. The method for constructing level equations for the system dynamics model is substantiated. For production lines with a different number of operations, the solution to the problem of processing parts along a production line is presented. The comparative analysis of the solutions obtained using the system dynamics and PDE model equations is obtained
{"title":"Using PDE Model and System Dynamics Model for Describing Multi-Operation Production Lines","authors":"O. Pihnastyi, D. Yemelianova, D. Lysytsia","doi":"10.15587/1729-4061.2020.210750","DOIUrl":"https://doi.org/10.15587/1729-4061.2020.210750","url":null,"abstract":"Two classes of models for describing production flow lines are analyzed. The use of models of these classes for the design of highly efficient control systems of production lines, the technological route of which consists of a large number of technological operations, is analyzed. The division of the technological route into a large number of operations is caused by the development trend of modern production lines. Synchronization of production line equipment performance is provided by an accumulating buffer. A formalized description of the production line was used as a foundation for constructing equations for each models class. The common features of using each models class in the description of production systems, as well as the conditions for their application, are shown. The form of the system dynamics model and PDE model equations is substantiated. The assumption about a deterministic rate of processing parts and the absence of a time delay and feedback between the parameters of technological operations was made when deriving the equations. The use of generalized technological operations in the system dynamics model as a way to reduce the number of model equations is discussed. Two limiting transitions from the PDE model equations to the system dynamics equations are demonstrated. It is shown that the system dynamics equations are a special case of the PDE model equations, the result of the aggregation of production line parameters within the technological operation. The method for constructing level equations for the system dynamics model is substantiated. For production lines with a different number of operations, the solution to the problem of processing parts along a production line is presented. The comparative analysis of the solutions obtained using the system dynamics and PDE model equations is obtained","PeriodicalId":18731,"journal":{"name":"Materials Processing & Manufacturing eJournal","volume":"34 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91480020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Dellasega, F. Mirani, D. Vavassori, Claudia Conti, Matteo Passoni
Titanium (Ti), due to its excellent properties, is widely exploited in thin film technology that usually leads to the production of {alpha}-phase (hcp) Ti films. In this work, we investigate the phase evolution of Ti films deposited by varying type and energy of the film-forming species. To investigate different plasma species environments, films with different thicknesses are grown by using conventional Direct Current Magnetron Sputtering (DCMS) and High Power Impulse Magnetron Sputtering (HiPIMS). Furthermore, HiPIMS depositions with different substrate bias voltage US (0 V, -300 V and -500 V) are performed to investigate different ion energy ranges. Microstructure, morphology and residual stress of the deposited films, as well as the DCMS and HiPIMS plasma composition, are analysed with different characterization techniques. The DCMS samples exhibit the Ti {alpha}-phase only and show a tensile residual stress decreasing with thickness. As far as HiPIMS samples are concerned, a compressive-tensile-compressive (CTC) behavior is observed for residual stresses as thickness increases. Specifically, films deposited in low energy ion conditions (US =0 V) show the presence of the Ti fcc phase up to a maximum thickness of about 370 nm. Differently, films deposited under high energy conditions (US = -300 V and -500 V) show the nucleation of the Ti {omega}-phase for thicknesses greater than 260 and 330 nm, respectively. The formation of these unusual Ti phases is discussed considering the different deposition conditions.
{"title":"Role of Energetic Ions in the Growth of fcc and ω Crystalline Phases in Ti Films Deposited by HiPIMS","authors":"David Dellasega, F. Mirani, D. Vavassori, Claudia Conti, Matteo Passoni","doi":"10.2139/ssrn.3693000","DOIUrl":"https://doi.org/10.2139/ssrn.3693000","url":null,"abstract":"Titanium (Ti), due to its excellent properties, is widely exploited in thin film technology that usually leads to the production of {alpha}-phase (hcp) Ti films. In this work, we investigate the phase evolution of Ti films deposited by varying type and energy of the film-forming species. To investigate different plasma species environments, films with different thicknesses are grown by using conventional Direct Current Magnetron Sputtering (DCMS) and High Power Impulse Magnetron Sputtering (HiPIMS). Furthermore, HiPIMS depositions with different substrate bias voltage US (0 V, -300 V and -500 V) are performed to investigate different ion energy ranges. Microstructure, morphology and residual stress of the deposited films, as well as the DCMS and HiPIMS plasma composition, are analysed with different characterization techniques. The DCMS samples exhibit the Ti {alpha}-phase only and show a tensile residual stress decreasing with thickness. As far as HiPIMS samples are concerned, a compressive-tensile-compressive (CTC) behavior is observed for residual stresses as thickness increases. Specifically, films deposited in low energy ion conditions (US =0 V) show the presence of the Ti fcc phase up to a maximum thickness of about 370 nm. Differently, films deposited under high energy conditions (US = -300 V and -500 V) show the nucleation of the Ti {omega}-phase for thicknesses greater than 260 and 330 nm, respectively. The formation of these unusual Ti phases is discussed considering the different deposition conditions.","PeriodicalId":18731,"journal":{"name":"Materials Processing & Manufacturing eJournal","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85614586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
X. Cao, Yuval Kaminer, T. Hong, Perry Schein, Ting-Chun Liu, T. Hanrath, D. Erickson
In this work, we introduce HI-Light, a surface-engineered glass waveguide based “shell-and-tube” type photothermal reactor which is both scalable in diameter and length. We examine the effect of temperature, light irradiation, and residence time on its photo-thermocatalytic performance for CO2 hydrogenation to form CO, with a cubic phase defect-laden indium oxide, In2O3-x(OH)y catalyst. We demonstrate the light enhancement effect under a variety of reaction conditions. Notably, the light-on performance for the cubic nanocrystal photocatalyst exhibits a CO evolution rate at 15.40 mmol gcat−1 h−1 at 300°C and atmospheric pressure. This is 20 times higher conversion rate beyond previously reported In2O3-x(OH)y catalyst in the cubic form under comparable operation conditions, and more than 5 times higher than that of its rhombohedral polymorph. This result underscores that improvement in photo-thermocatalytic reactor design enables uniform light distribution and better reactant/catalyst mixing, thus significantly improving catalyst utilization.
{"title":"HI-Light: A Glass Waveguide Based 'Shell-and-Tube' Photothermal Reactor Platform for Converting CO 2 to Fuels","authors":"X. Cao, Yuval Kaminer, T. Hong, Perry Schein, Ting-Chun Liu, T. Hanrath, D. Erickson","doi":"10.2139/ssrn.3636568","DOIUrl":"https://doi.org/10.2139/ssrn.3636568","url":null,"abstract":"In this work, we introduce HI-Light, a surface-engineered glass waveguide based “shell-and-tube” type photothermal reactor which is both scalable in diameter and length. We examine the effect of temperature, light irradiation, and residence time on its photo-thermocatalytic performance for CO2 hydrogenation to form CO, with a cubic phase defect-laden indium oxide, In2O3-x(OH)y catalyst. We demonstrate the light enhancement effect under a variety of reaction conditions. Notably, the light-on performance for the cubic nanocrystal photocatalyst exhibits a CO evolution rate at 15.40 mmol gcat−1 h−1 at 300°C and atmospheric pressure. This is 20 times higher conversion rate beyond previously reported In2O3-x(OH)y catalyst in the cubic form under comparable operation conditions, and more than 5 times higher than that of its rhombohedral polymorph. This result underscores that improvement in photo-thermocatalytic reactor design enables uniform light distribution and better reactant/catalyst mixing, thus significantly improving catalyst utilization.","PeriodicalId":18731,"journal":{"name":"Materials Processing & Manufacturing eJournal","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83289870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Changjun Cheng, Yuan Xiao, M. Haché, Zhiying Liu, A. Sologubenko, J. Wheeler, Y. Zou
Quasicrystalline materials possess a unique structure that is ordered yet not periodic. Despite their special configuration and many useful properties, they are typically very brittle at temperatures below ~75% of their melting points, rendering them difficult to process and often unsuitable for practical implementation. Here, we study the mechanical behavior of a typical icosahedral quasicrystal (i-Al-Pd-Mn) using micro-thermomechanical techniques over the temperature range of 25-500 °C, which has never been explored before. A few interesting phenomena have been observed, including micro-pillar shrinkage, phase transformations, grain refinement, and thermally induced transitions in deformation behavior (from brittle fracture to serrated plastic flows, and then to homogeneous flows). Furthermore, we discuss the multiple underlying mechanisms on the mechanical behavior of the quasicrystal in this temperature regime, exploring surface evaporation/diffusion, diffusion-enhanced plasticity, dislocation activities, and grain boundary rotation/sliding. Our study bridges the gap between room-temperature and high-temperature plasticity in quasicrystals, demonstrating a new opportunity to study complex intermetallic phases in broad size and temperature regimes.
{"title":"Probing the Small-Scale Plasticity of an Icosahedral Quasicrystal I-Al-Pd-Mn at Elevated Temperatures","authors":"Changjun Cheng, Yuan Xiao, M. Haché, Zhiying Liu, A. Sologubenko, J. Wheeler, Y. Zou","doi":"10.2139/ssrn.3646446","DOIUrl":"https://doi.org/10.2139/ssrn.3646446","url":null,"abstract":"Quasicrystalline materials possess a unique structure that is ordered yet not periodic. Despite their special configuration and many useful properties, they are typically very brittle at temperatures below ~75% of their melting points, rendering them difficult to process and often unsuitable for practical implementation. Here, we study the mechanical behavior of a typical icosahedral quasicrystal (i-Al-Pd-Mn) using micro-thermomechanical techniques over the temperature range of 25-500 °C, which has never been explored before. A few interesting phenomena have been observed, including micro-pillar shrinkage, phase transformations, grain refinement, and thermally induced transitions in deformation behavior (from brittle fracture to serrated plastic flows, and then to homogeneous flows). Furthermore, we discuss the multiple underlying mechanisms on the mechanical behavior of the quasicrystal in this temperature regime, exploring surface evaporation/diffusion, diffusion-enhanced plasticity, dislocation activities, and grain boundary rotation/sliding. Our study bridges the gap between room-temperature and high-temperature plasticity in quasicrystals, demonstrating a new opportunity to study complex intermetallic phases in broad size and temperature regimes.","PeriodicalId":18731,"journal":{"name":"Materials Processing & Manufacturing eJournal","volume":"68 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91466433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The material handling vehicles usually take more time to adjust its position, and unload at the exact location. The system now available is to unload material on back side. As considering the mines space available is less due to which unloading raw material on left or right side is not possible to take this as a problem multi directional trolley is the solution.This paper explain the design and fabricate a trolley with 3 directional unloading and lifting arrangement. This mechanism is proposed to make the unloading easier in multi direction,only by providing 3 directional movement to the trolley rather than the vehicle in order to make the work more economic and efficient. The dumping will be done by using pneumatic cylinder, the compressed air will pass from the compressor to the direction control valve which will control the compressed air according to the required action (forward or backward stroke).
{"title":"Design & Fabrication of Pneumatic Weight Lifting Trolley With 3 Way Movement","authors":"Piyush Laad","doi":"10.2139/ssrn.3644974","DOIUrl":"https://doi.org/10.2139/ssrn.3644974","url":null,"abstract":"The material handling vehicles usually take more time to adjust its position, and unload at the exact location. The system now available is to unload material on back side. As considering the mines space available is less due to which unloading raw material on left or right side is not possible to take this as a problem multi directional trolley is the solution.This paper explain the design and fabricate a trolley with 3 directional unloading and lifting arrangement. \u0000 \u0000This mechanism is proposed to make the unloading easier in multi direction,only by providing 3 directional movement to the trolley rather than the vehicle in order to make the work more economic and efficient. The dumping will be done by using pneumatic cylinder, the compressed air will pass from the compressor to the direction control valve which will control the compressed air according to the required action (forward or backward stroke).","PeriodicalId":18731,"journal":{"name":"Materials Processing & Manufacturing eJournal","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88946153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-30DOI: 10.15587/1729-4061.2020.203737
V. Liubych, V. Novikov, V. Zheliezna, V. Prykhodko, V. Petrenko, S. Khomenko, Viktor Zorunko, O. Balabak, V. Moskalets, T. Moskalets
The influence of hydrothermal treatment (grain moistening) and dehulling duration on the yield and quality of groats from different fractions of triticale grain was studied. Comparative analysis of groats yield and its culinary quality at different grain moisture, depending on its fractions, was performed. The degree of the influence of the studied factors on the yield and quality of triticale groats was determined. The influence of dehulling duration, the size of a triticale caryopsis and grain moisture content is reliable. These factors significantly influenced the groats yield and quality. In addition, the influence of the duration of grain dehulling was the highest. The highest groats yield was obtained at the dehulling duration of 20 s, the lowest – at dehulling for 180 s. The social survey was conducted and the main priorities for buyers of cereal products were established. It was proved that while choosing food, consumers pay the most attention to culinary characteristics of the finished product. It was established that it is optimal to dehull triticale grain for 100 s. The application of such parameters of treatment makes it possible to obtain the yield of whole groats of 88.8 % with the culinary quality of 6.7 points. The groats quality meets the requirements of DSTU 76992015 "Wheat Groats. Technical specifications". Based on the research, it was established that the separation of the triticale grain into fractions that differ in their geometric properties, in particular, thickness, is effective. The peculiarities of groats yield, depending on the triticale grain fraction, were determined. Application of hydrothermal treatment of triticale grain (moistening up to 14.0 %) makes it possible to increase the groats yield up to 88.7 %. The treatment of the fractions with grain thickness less than 2.4 mm ensures the groats yield up to 87.8 %. The groats yield during dehulling the grain, which has a thickness of more than 2.4 mm, is from 88.8 to 89.1 %. To produce the groats from triticale grain, it is advisable to use the grains that have a thickness of 2.8 mm or more. The optimum duration of dehulling is 100 s. To increase the overall culinary assessment by 1 point, it is recommended to increase the duration of dehulling a large grain up to 140 s. This method differs from the classical one by the fact that it uses a large grain fraction with the lower moisture content. The developed recommendations can be used by grain processing enterprises during processing triticale with the view to intensifying the production.
{"title":"Improving the Process of Hydrothermal Treatment and Dehulling of Different Triticale Grain Fractions in the Production of Groats","authors":"V. Liubych, V. Novikov, V. Zheliezna, V. Prykhodko, V. Petrenko, S. Khomenko, Viktor Zorunko, O. Balabak, V. Moskalets, T. Moskalets","doi":"10.15587/1729-4061.2020.203737","DOIUrl":"https://doi.org/10.15587/1729-4061.2020.203737","url":null,"abstract":"The influence of hydrothermal treatment (grain moistening) and dehulling duration on the yield and quality of groats from different fractions of triticale grain was studied. Comparative analysis of groats yield and its culinary quality at different grain moisture, depending on its fractions, was performed. The degree of the influence of the studied factors on the yield and quality of triticale groats was determined. The influence of dehulling duration, the size of a triticale caryopsis and grain moisture content is reliable. These factors significantly influenced the groats yield and quality. In addition, the influence of the duration of grain dehulling was the highest. The highest groats yield was obtained at the dehulling duration of 20 s, the lowest – at dehulling for 180 s. The social survey was conducted and the main priorities for buyers of cereal products were established. It was proved that while choosing food, consumers pay the most attention to culinary characteristics of the finished product. It was established that it is optimal to dehull triticale grain for 100 s. The application of such parameters of treatment makes it possible to obtain the yield of whole groats of 88.8 % with the culinary quality of 6.7 points. The groats quality meets the requirements of DSTU 76992015 \"Wheat Groats. Technical specifications\". Based on the research, it was established that the separation of the triticale grain into fractions that differ in their geometric properties, in particular, thickness, is effective. The peculiarities of groats yield, depending on the triticale grain fraction, were determined. Application of hydrothermal treatment of triticale grain (moistening up to 14.0 %) makes it possible to increase the groats yield up to 88.7 %. The treatment of the fractions with grain thickness less than 2.4 mm ensures the groats yield up to 87.8 %. The groats yield during dehulling the grain, which has a thickness of more than 2.4 mm, is from 88.8 to 89.1 %. To produce the groats from triticale grain, it is advisable to use the grains that have a thickness of 2.8 mm or more. The optimum duration of dehulling is 100 s. To increase the overall culinary assessment by 1 point, it is recommended to increase the duration of dehulling a large grain up to 140 s. This method differs from the classical one by the fact that it uses a large grain fraction with the lower moisture content. The developed recommendations can be used by grain processing enterprises during processing triticale with the view to intensifying the production.","PeriodicalId":18731,"journal":{"name":"Materials Processing & Manufacturing eJournal","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83737258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wet Scrubbers working depends on the type of gas contaminant whether it is a solid, liquid, odour or recovery a variety of collection mechanisms and scrubbing liquid types are used. For gaseous contaminants, mass transfer is the mechanism that absorbs the gas into a liquid through creation of liquid films or droplets. Large surface area packing media, trays, fluidized beds and hydraulic or shear atomization techniques are mostly used to create the films and droplets necessary for mass transfer to occur. A chemical reagent scrubbing liquid is incorporated in many cases to enhance removal of contaminants by producing a stable salt by-product. The predominant mechanism used for particulate collection is impaction between the particle contained in the gas stream and liquid droplets. The liquid droplet encapsulates the particle into a larger size so both can be removed from the cleaned gas stream either centrifugally or by means of mist eliminator elements. The smaller the size of the particle the smaller the size of the droplet needed to collect the particle. Normally a droplet no larger than 10 times the size of the particle must be used. The smaller the droplet the more energy it takes to create it either hydraulically or through gas shear effects. For hot gases scrubbing system has perfected a method to condense water vapour onto the particle to achieve a larger size agglomerated mass to increase removal efficiency at reduced energy cost. Hydrophobic particles are also hard to scrub wherein it is perfected chemical additions to the scrubbing liquid to overcome the problem. There are various control devices for controlling particulate contaminants however article covers only on the wet scrubbing system in detail.
{"title":"Efficient Operation of Wet Scrubbing System in Pollution Containment","authors":"Ghanshyamprasad Manibhai Patel","doi":"10.2139/ssrn.3633910","DOIUrl":"https://doi.org/10.2139/ssrn.3633910","url":null,"abstract":"Wet Scrubbers working depends on the type of gas contaminant whether it is a solid, liquid, odour or recovery a variety of collection mechanisms and scrubbing liquid types are used. \u0000 \u0000For gaseous contaminants, mass transfer is the mechanism that absorbs the gas into a liquid through creation of liquid films or droplets. Large surface area packing media, trays, fluidized beds and hydraulic or shear atomization techniques are mostly used to create the films and droplets necessary for mass transfer to occur. A chemical reagent scrubbing liquid is incorporated in many cases to enhance removal of contaminants by producing a stable salt by-product. \u0000 \u0000The predominant mechanism used for particulate collection is impaction between the particle contained in the gas stream and liquid droplets. The liquid droplet encapsulates the particle into a larger size so both can be removed from the cleaned gas stream either centrifugally or by means of mist eliminator elements. The smaller the size of the particle the smaller the size of the droplet needed to collect the particle. Normally a droplet no larger than 10 times the size of the particle must be used. The smaller the droplet the more energy it takes to create it either hydraulically or through gas shear effects. For hot gases scrubbing system has perfected a method to condense water vapour onto the particle to achieve a larger size agglomerated mass to increase removal efficiency at reduced energy cost. Hydrophobic particles are also hard to scrub wherein it is perfected chemical additions to the scrubbing liquid to overcome the problem. There are various control devices for controlling particulate contaminants however article covers only on the wet scrubbing system in detail.","PeriodicalId":18731,"journal":{"name":"Materials Processing & Manufacturing eJournal","volume":"309 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79913084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. B. Kim, Seungman Jung, Hyukjin Park, D. Sim, Moonki Kim, Youngkeun Ahn, M. Jeong, Y. Hong
Objectives: Clinical reproducibility of large animal models is important for developing new therapies for myocardial infarction (MI) and ischemic heart failure (IHF). This study aimed to induce MI and IHF in a swine model by using 3D bioprinted occluders to interrupt intravascular blood flow permanently. Methods: The 3D bioprinted occluder was placed in the proximal left anterior descending artery using a guide wire and a balloon catheter. Echocardiography was performed at the baseline, post MI (day 7-14), and at 28 days follow-up after the placement of the occluder to evaluate cardiac function. Quantitative coronary angiography was performed at baseline, post MI (immediately after the procedure) and at 42 days follow-up. Histopathology confirmed the deformation of the heart tissue and hypoxic damage.Results: Luminal diameter distal to the 3D bioprinted occluder was significantly reduced from the baseline to 42 days follow-up and left ventricular (LV) ejection fraction gradually decreased from the baseline to 28 days follow-up after the induction of MI. Tetrazolium staining showed firm and white area of the infarction in the LV apex and LV anterior wall. Hematoxylin and eosin stained section samples showed loss of normal architecture and morphology of myocytes in the LV myocardium. In addition, HIF-1 alpha was expressed in the ischemic myocardium area by immunohistochemistry staining. Conclusions: The customized occluder via 3D bioprinting technology could induce a stable, consistent and reproducible swine MI and IHF model.
{"title":"Production of Swine Myocardial Infarction and Ischemic Heart Failure Models Using a Three-Dimensional Bioprinted Occluder","authors":"H. B. Kim, Seungman Jung, Hyukjin Park, D. Sim, Moonki Kim, Youngkeun Ahn, M. Jeong, Y. Hong","doi":"10.2139/ssrn.3606016","DOIUrl":"https://doi.org/10.2139/ssrn.3606016","url":null,"abstract":"Objectives: Clinical reproducibility of large animal models is important for developing new therapies for myocardial infarction (MI) and ischemic heart failure (IHF). This study aimed to induce MI and IHF in a swine model by using 3D bioprinted occluders to interrupt intravascular blood flow permanently. Methods: The 3D bioprinted occluder was placed in the proximal left anterior descending artery using a guide wire and a balloon catheter. Echocardiography was performed at the baseline, post MI (day 7-14), and at 28 days follow-up after the placement of the occluder to evaluate cardiac function. Quantitative coronary angiography was performed at baseline, post MI (immediately after the procedure) and at 42 days follow-up. Histopathology confirmed the deformation of the heart tissue and hypoxic damage.Results: Luminal diameter distal to the 3D bioprinted occluder was significantly reduced from the baseline to 42 days follow-up and left ventricular (LV) ejection fraction gradually decreased from the baseline to 28 days follow-up after the induction of MI. Tetrazolium staining showed firm and white area of the infarction in the LV apex and LV anterior wall. Hematoxylin and eosin stained section samples showed loss of normal architecture and morphology of myocytes in the LV myocardium. In addition, HIF-1 alpha was expressed in the ischemic myocardium area by immunohistochemistry staining. Conclusions: The customized occluder via 3D bioprinting technology could induce a stable, consistent and reproducible swine MI and IHF model.","PeriodicalId":18731,"journal":{"name":"Materials Processing & Manufacturing eJournal","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84809406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cloud computing facilitates service providers to rent their computing capabilities for deploying applications depending on user requirements. Applications of cloud have diverse composition, configuration and deployment requirements. Quantifying the performance of applications in Cloud computing environments is a challenging task. In this paper, we try to identify various parameters associated with performance of cloud applications and analyse the impact of resource management and scalability among them.
{"title":"Impact of Resource Management and Scalability on Performance of Cloud Applications – A Survey","authors":"P. Ganesh","doi":"10.2139/ssrn.3617706","DOIUrl":"https://doi.org/10.2139/ssrn.3617706","url":null,"abstract":"Cloud computing facilitates service providers to rent their computing capabilities for deploying applications depending on user requirements. Applications of cloud have diverse composition, configuration and deployment requirements. Quantifying the performance of applications in Cloud computing environments is a challenging task. In this paper, we try to identify various parameters associated with performance of cloud applications and analyse the impact of resource management and scalability among them.","PeriodicalId":18731,"journal":{"name":"Materials Processing & Manufacturing eJournal","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89400506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The ultimate granulation plant is the plant that can make multiple formulations (N, P, K, S, MN) of granular products including DAP, MAP, NPK, NP(K)S, and TSP and can also add Micro-Nutrients. In the past a granulation plant made one product and shipped the product to a retailer that blended ingredients for the customer. Today the trend is to have the fertilizer producer combine the ingredients in the granulation process for the customer. The reason for the trend away from the blend plant is consistency in chemistry appearance and size. The fertilizer blend eventually segregates into the original components resulting in unequal distribution of the different chemical components on the field. If the ingredients are combined in the granule, they cannot segregate which results in a more consistent application of the components. The ultimate granulation plant produces granules with all the components mixed together. JESA Technologies is involved in designing granulation plants capable of making many different formulations. This paper will review design considerations for the ultimate plant including the technology basis, major equipment selection, and process operating factors that impact the productivity of the granulation train.
{"title":"The Ultimate Granulation Plant","authors":"C. Dennis, Soukaina Ettouimi","doi":"10.2139/ssrn.3595381","DOIUrl":"https://doi.org/10.2139/ssrn.3595381","url":null,"abstract":"The ultimate granulation plant is the plant that can make multiple formulations (N, P, K, S, MN) of granular products including DAP, MAP, NPK, NP(K)S, and TSP and can also add Micro-Nutrients. In the past a granulation plant made one product and shipped the product to a retailer that blended ingredients for the customer. Today the trend is to have the fertilizer producer combine the ingredients in the granulation process for the customer. The reason for the trend away from the blend plant is consistency in chemistry appearance and size. The fertilizer blend eventually segregates into the original components resulting in unequal distribution of the different chemical components on the field. If the ingredients are combined in the granule, they cannot segregate which results in a more consistent application of the components. \u0000 \u0000The ultimate granulation plant produces granules with all the components mixed together. JESA Technologies is involved in designing granulation plants capable of making many different formulations. This paper will review design considerations for the ultimate plant including the technology basis, major equipment selection, and process operating factors that impact the productivity of the granulation train.","PeriodicalId":18731,"journal":{"name":"Materials Processing & Manufacturing eJournal","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87751262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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