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Gabapentin for cessation of smoking and non-smoking tobacco habits in Indian population. 加巴喷丁对印度人群戒烟和非吸烟习惯的影响。
Q3 Medicine Pub Date : 2020-10-23 DOI: 10.23736/S0026-4970.20.04410-6
A. Chaurasia, S. Ishrat, Rini Tiwari
BACKGROUNDThe effectiveness of Gabapentin in tobacco dependence has been evaluated by many researchers.The randomized control trials, testing the efficacy of gabapentin in quitting the habit in smokers and users of smokeless tobacco have not been published yet.We attempt to address this lacuna in knowledge in reducing dependence on tobacco use by Gabapentin.METHODSOur study involves 150 study subjects, 75 of whom were identified as chronic users of tobacco and assigned randomly to one of the three groups consisting of 25 subjects each. Gabapentin in tablet form was prescribed thrice a day for 8 weeks wherein Group 1 received a dose of 300mg, Group-2 received 600mg, and Group-3 was prescribed 900 mg. An age and sex matched control group have received calcium tablets as placebo in three times daily dose for a period of 8 weeks.RESULTSAmong the three doses of Gabapentin, stoppage of habit was reported to be highest in the group-2 followed by group 1 and group 3 respectively. In our study, we found differences in response to quitting tobacco use between duration of habit prior to pharmacologic intervention amongst both smokers and the users of smokeless tobacco.CONCLUSIONSGabapentin at dose of 600mg TDS has optimum effect. Smokers having smoking for more than ten years showed notable benefit with Gabapentin. Among smokeless tobacco users who quit tobacco dependence was better having history of habit less than 2 years.
背景Gabapentin治疗烟草依赖的有效性已被许多研究人员评估。测试加巴喷丁对吸烟者和无烟烟草使用者戒烟效果的随机对照试验尚未发表。我们试图解决Gabapentin在减少烟草使用依赖性方面的知识空白。我们的研究涉及150名研究受试者,其中75人被确定为慢性烟草使用者,并被随机分配到三组中的一组,每组25名受试者。加巴喷丁片剂每天三次,持续8周,其中第1组给药300mg,第2组给药600mg,第3组给药900mg。年龄和性别匹配的对照组接受钙片作为安慰剂,每日三次,为期8周。结果在加巴喷丁三个剂量组中,2组的习惯停止率最高,其次是1组和3组。在我们的研究中,我们发现吸烟者和无烟烟草使用者在药物干预前的习惯持续时间之间对戒烟的反应存在差异。结论加巴喷丁在总溶解固体浓度600mg时效果最佳。吸烟超过十年的吸烟者对Gabapentin表现出显著的益处。在戒烟者中,戒烟史少于2年的人更好。
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引用次数: 0
Surgical conservative approach of odontogenic keratocyst tumor of the jaws. 颌骨牙源性角化囊肿肿瘤的保守手术入路。
Q3 Medicine Pub Date : 2020-10-23 DOI: 10.23736/S0026-4970.20.04422-2
L. Laino, D. Russo, M. Cicciu', C. D’Amico, L. Fiorillo, G. Cervino
OBJECTIVEOdontogenic keratocyst (OKC) can be classified as an oral lesion representing the third most common cyst of the jaws characterized by a high rate of recurrence. OKC was accepted as a neoplastic lesion in the 2005 WHO classification and it was called keratocystic odontogenic tumor (KCOT). However, in the 2017 classification of odontogenic tumors, OKC was moved back into the cyst category. This study aims to evaluate clinically, radiographically and through the histological examination the healing of a patient with OKC who underwent surgery with a marsupialization approach.DESIGNAn 83-year-old female patient, presented deformation of the right hemi-mandibular region and paresthesia of the right hemi-labium, during intraoral examination it was possible to detect an eggshell crackle on palpation of the anterior edentulous mandible, moreover, the patient reported a growth of the lesion over time that prevented her from using the removable prosthesis.METHODSAt the OPT it was possible to appreciate a unilocular area that extended from the parasymphyseal region to the right hemi-mandible. The CT scan showed massive erosion that only partially spared the lower cortex and involvement of the mental foramen.RESULTSChecks following surgery show healing also confirmed by instrumental check-ups.CONCLUSIONSSurely this study offers a valid alternative to more invasive and debilitating surgical treatments.
目的牙源性角化囊肿(OKC)是一种口腔病变,是下颌第三常见的囊肿,其特点是复发率高。OKC在2005年WHO分类中被认为是一种肿瘤性病变,被称为角化囊性牙源性肿瘤(KCOT)。然而,在2017年牙源性肿瘤的分类中,OKC被移回囊肿类别。本研究旨在通过临床,影像学和组织学检查评估OKC患者接受有袋化入路手术的愈合情况。设计一名83岁女性患者,表现为右半下颌区变形和右半阴唇感觉异常,在口腔内检查时,触诊前无牙下颌骨可发现蛋壳裂纹,而且,患者报告病变随着时间的推移而增长,使她无法使用可拆卸假体。方法在OPT下,可以观察到从副淋巴区延伸到右半下颌骨的单眼区域。CT扫描显示大面积的侵蚀,仅部分保留了下皮层和累及的精神孔。结果手术后检查显示愈合,器械检查也证实了愈合。结论:本研究无疑为更具侵入性和破坏性的手术治疗提供了一种有效的选择。
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引用次数: 5
Autotransplantation of third molar for oro-antral communication closure: case report with evidence of sinus elevation after healing. 自体第三磨牙移植用于口腔-窦间交通闭合:一例报告,有证据表明术后窦抬高。
Q3 Medicine Pub Date : 2020-10-23 DOI: 10.23736/S0026-4970.20.04331-9
M. Melillo, L. Boschini
BACKGROUNDOro-antral communication is a complication due to the extraction of the posterior teeth of the upper arch. Small lesions are able to spontaneously close, but larger diameter lesions require a surgical treatment.METHODSA compromised upper first molar had to be extract determining an oro-antral communication (OAC). Several techniques have been described for the management of OACs, but none of these techniques guarantees bone healing or immediate rehabilitation. In the case of the present report an autotransplantation of the ipsilateral third molar was performed for closing the communication and rehabilitate the extracted tooth.RESULTSThe transplantation of the third molar determined the immediate closure of the oroantral communication without resorting to more invasive surgical procedures. The 1,5 years follow up showed the bone healing and the complete oro-antral communication closure. During healing, the palatal root, that was invading the sinus, caused a vertical bone augmentation making a sinus lifting.CONCLUSIONSWhen a donor tooth is available, the autogenous transplantation could be used to manage the closure of oro-antral communication due to its high regenerative potential.
背景上颌窦沟通是由于上弓后牙拔除引起的并发症。小的病变可以自发闭合,但直径较大的病变需要手术治疗。方法必须提取受损的上第一磨牙,以确定口腔-窦间通讯(OAC)。已经描述了几种用于OACs管理的技术,但这些技术都不能保证骨愈合或立即康复。在本报告的情况下,进行了同侧第三磨牙的自体种植,以关闭通讯并修复拔出的牙齿。结果第三磨牙的移植决定了在不采用更具侵入性的外科手术的情况下立即关闭口窦通道。1,5年的随访显示骨愈合,口腔-窦沟通完全闭合。在愈合过程中,腭根侵入鼻窦,导致垂直骨增大,使鼻窦抬高。结论:当有供牙可用时,自体移植可用于管理口窦沟通的闭合,因为其具有很高的再生潜力。
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引用次数: 0
A new software architecture proposal for an evidence-based Decision Support System in dentistry. 一种基于证据的牙科决策支持系统的新软件架构方案。
Q3 Medicine Pub Date : 2020-10-23 DOI: 10.23736/S0026-4970.20.04416-7
G. Lo Giudice, A. Lizio, R. Lo Giudice
BACKGROUNDin dentistry, clinical problems could be resolved using many therapeutic approaches that may results in very different therapies. In order to choose the best option, a good evaluation of therapy long-term survival and success rate is mandatory. The routine use of a decision support analysis software is nowadays limited due to the lack of software's flexibility especially when a variety of possible therapeutic option are present. The aim of this research is to develop a new algorithm model for a Decision Support System software to give diagnosis support in dentistry.METHODSBeta tests were designed to study the computer software in different clinical situations based on clinical data. The therapeutic options can be conservative/endodontic or extractive/prosthetic therapies. In two of clinical situation selected could be possible to choose both therapies.RESULTSin clinical situations tested, the DDS software correctly identified the several therapeutic options.When multiple treatments were possible the beta test showed an output mask that correctly showed a range of options with their corresponding survival and success rate.CONCLUSIONSThe software architecture proposed by the Authors is technically feasible, can support the clinician choices based on scientific evidences and up-to-date references and gain informed consent based on data easily understandable for the patient.
在牙科,临床问题可以通过许多治疗方法来解决,这可能导致非常不同的治疗方法。为了选择最佳方案,必须对治疗的长期生存和成功率进行良好的评估。决策支持分析软件的常规使用目前是有限的,由于缺乏软件的灵活性,特别是当各种可能的治疗方案存在。本研究的目的是为决策支持系统软件开发一种新的算法模型,以提供牙科诊断支持。方法根据临床资料设计beta测试,研究计算机软件在不同临床情况下的应用。治疗选择可以是保守治疗/牙髓治疗或拔牙治疗/修复治疗。在两种临床情况下均可选择两种治疗方法。结果在临床情况测试中,DDS软件正确识别了几种治疗方案。当多种治疗是可能的,beta测试显示了一个输出掩模,正确地显示了一系列的选择及其相应的存活率和成功率。结论本文提出的软件架构在技术上是可行的,可以支持临床医生基于科学证据和最新参考文献进行选择,并根据患者易于理解的数据获得知情同意。
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引用次数: 1
In Vitro study on the effectiveness of microwave sterilization in odontostomatology. 微波杀菌在口腔医学中的有效性体外研究。
Q3 Medicine Pub Date : 2020-10-23 DOI: 10.23736/S0026-4970.20.04427-1
C. D’Amico, L. Fiorillo, G. Surace, G. Cervino, M. Cicciu'
BACKGROUNDDental practice is subjected to biologic risk on a daily basis, a risk that could affect both operators and patients. The use of protective devices and medical devices allows to limit and eliminate this risk, especially in the case of cross infections.METHODSThe methods of disinfection of surfaces and instruments are different, and could include both physical and chemical methods. In this in vitro study the effectiveness of sterilization of microwave methods was assessed. In this study microwave sterilization with a 1800W protocol for 5 minutes has been performed.RESULTSOnce the bacterial contamination of some dental instruments was carried out, and left the latter in culture medium, the disinfection phase was carried out, by inserting the instruments in a microwave chamber. These new sterilization protocols allow to obtain surfaces or instruments sterilization in a short time.CONCLUSIONSThe use of this method, although it cannot be used with all materials, has excellent properties for the sterilization of dental medical instruments, even if with lower performance than the conventional autoclave.
背景牙科诊所每天都会面临生物风险,这种风险可能会影响手术人员和患者。使用防护设备和医疗设备可以限制和消除这种风险,尤其是在交叉感染的情况下。方法表面和仪器的消毒方法不同,可能包括物理方法和化学方法。在这项体外研究中,评估了微波灭菌方法的有效性。在本研究中,采用1800W方案进行了5分钟的微波灭菌。结果对一些牙科器械进行了细菌污染,并将后者留在培养基中,通过将器械插入微波室进行消毒。这些新的灭菌方案允许在短时间内对表面或仪器进行灭菌。结论该方法虽然不能与所有材料一起使用,但在牙科医疗器械的灭菌方面具有优异的性能,即使其性能低于传统的高压灭菌器。
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引用次数: 2
Oral manifestations in chronic kidney disease patients undergoing hemodialysis: a hospital-based study. 接受血液透析的慢性肾病患者的口腔表现:一项基于医院的研究
Q3 Medicine Pub Date : 2020-10-01 Epub Date: 2020-05-14 DOI: 10.23736/S0026-4970.20.04300-9
Swati Kumar, Ravindranath Vineetha, Keerthilatha M Pai, Ravindra Prabhu, Vathsala Patil, Komal Smriti

Background: Chronic kidney disease (CKD-HD) patients undergoing routine hemodialysis have been reported to have oral signs and symptoms due to disease process or various comorbidities like diabetes mellitus (DM). Both CKD and DM can cause oral changes. Hence this study aimed to evaluate the prevalence of oral symptoms and signs in CKD-HD patients and to rule out DM as possible confounding factor for the oral findings.

Methods: Oral manifestations were assessed in 102 CKD-HD patients, and compared with 100 DM patients and 101 non-diabetic patients with no renal impairment.

Results: Most common symptom reported by patients with CKD-HD were xerostomia, altered taste. The most prevalent objective findings were oral dryness. There was statistically significant difference in symptoms and signs between CKD-HD and non-CKD patients. However, no significant difference between CKD-HD with and without DM.

Conclusions: This study showed increased prevalence of oral findings in CKD patients. It also revealed that Diabetes mellitus cannot be a contributing factor for increased prevalence of oral manifestations in CKD patients.

背景:慢性肾脏疾病(CKD-HD)患者接受常规血液透析有报道,由于疾病进程或各种合并症,如糖尿病(DM)有口腔体征和症状。慢性肾病和糖尿病都可引起口腔病变。因此,本研究旨在评估CKD-HD患者口腔症状和体征的患病率,并排除DM可能是口腔发现的混杂因素。方法:对102例CKD-HD患者的口腔表现进行评估,并与100例DM患者和101例无肾脏损害的非糖尿病患者进行比较。结果:CKD-HD患者最常见的症状是口干、味觉改变。最普遍的客观结果是口腔干燥。CKD-HD与非ckd患者在症状和体征上有统计学差异。然而,CKD- hd合并和不合并dm之间没有显著差异。结论:本研究显示CKD患者口腔病变的患病率增加。研究还表明,糖尿病不可能是CKD患者口腔表现患病率增加的一个因素。
{"title":"Oral manifestations in chronic kidney disease patients undergoing hemodialysis: a hospital-based study.","authors":"Swati Kumar,&nbsp;Ravindranath Vineetha,&nbsp;Keerthilatha M Pai,&nbsp;Ravindra Prabhu,&nbsp;Vathsala Patil,&nbsp;Komal Smriti","doi":"10.23736/S0026-4970.20.04300-9","DOIUrl":"https://doi.org/10.23736/S0026-4970.20.04300-9","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease (CKD-HD) patients undergoing routine hemodialysis have been reported to have oral signs and symptoms due to disease process or various comorbidities like diabetes mellitus (DM). Both CKD and DM can cause oral changes. Hence this study aimed to evaluate the prevalence of oral symptoms and signs in CKD-HD patients and to rule out DM as possible confounding factor for the oral findings.</p><p><strong>Methods: </strong>Oral manifestations were assessed in 102 CKD-HD patients, and compared with 100 DM patients and 101 non-diabetic patients with no renal impairment.</p><p><strong>Results: </strong>Most common symptom reported by patients with CKD-HD were xerostomia, altered taste. The most prevalent objective findings were oral dryness. There was statistically significant difference in symptoms and signs between CKD-HD and non-CKD patients. However, no significant difference between CKD-HD with and without DM.</p><p><strong>Conclusions: </strong>This study showed increased prevalence of oral findings in CKD patients. It also revealed that Diabetes mellitus cannot be a contributing factor for increased prevalence of oral manifestations in CKD patients.</p>","PeriodicalId":18742,"journal":{"name":"Minerva stomatologica","volume":"69 5","pages":"302-308"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37934463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A split-mouth study comparing piezo electric surgery and traditional rotary burs on impacted third molars in young patients: an intraoperative and postoperative evaluation. 一项劈口研究比较压电手术和传统旋转毛刺治疗年轻患者阻生第三磨牙:术中和术后评价。
Q3 Medicine Pub Date : 2020-10-01 Epub Date: 2020-05-14 DOI: 10.23736/S0026-4970.20.04349-6
Francesca Zara, Claudio M De Sanctis, Fabia C Dede, Maurizio Bossù, Gian L Sfasciotti

Background: Piezoelectric surgery has been used in many different medical fields, for instance it is used in the field of oral surgery, as a valuable alternative to traditional rotary burs. Its first use dates to 1975 by Horton even if the first effective device for use in dentistry, has been developed by Vercellotti after the year 2000. The hypothesis of this study is that piezosurgery technology is more suitable in terms of specific intra-operative and postoperative evaluations compared to the rotary technology in ostectomy for the avulsion of the third molar germ. The null hypothesis presented is the lack of significant differences between the two technologies after and during surgery.

Methods: Intraoperative and postoperative aspects are evaluated for a comparison between traditional rotary instruments and piezosurgery during germectomies in young patients through a blind randomized study (split-mouth). The surgical technique to employ for each hemi-arch was randomly selected from a computer algorithm. Different criteria were considered during the surgical procedure, in order to compare the two techniques.

Results: The piezoelectric technique demanded more time than traditional rotary method, and the difference was statistically significant both for the time of the entire procedure and the time only required for the ostectomy itself. Postoperative evaluations such as maximum mouth opening, facial swelling and postoperative pain showed no statistical difference.

Conclusions: Even if the adopted clinical trial did not highlight any statistical difference the following review of literature showed an encouraging reduction in postoperative discomfort given by the piezosurgery as opposed to the traditional rotary bur surgery. The time taken to complete the operation, however, was longer with piezosurgery compared to traditional burs.

背景:压电手术已被应用于许多不同的医学领域,例如它被用于口腔外科领域,作为传统旋转刺的一种有价值的替代品。它的第一次使用可以追溯到1975年的霍顿,尽管第一个用于牙科的有效设备是在2000年后由Vercellotti开发的。本研究的假设是,在第三磨牙胚根撕脱伤的截骨手术中,与旋转技术相比,在具体的术中和术后评估方面,piezosurgery技术更适合。提出的零假设是两种技术在手术后和手术中没有显著差异。方法:通过一项盲随机研究(裂口),对年轻患者进行生殖切除术时传统旋转器械和压电手术在术中和术后的比较进行评估。每个半弓的手术技术是从计算机算法中随机选择的。在手术过程中考虑了不同的标准,以便比较两种技术。结果:压电法比传统的旋转法所需的时间更长,无论是整个手术过程的时间还是仅切除本身所需的时间,差异均有统计学意义。术后评价如最大开口、面部肿胀和术后疼痛无统计学差异。结论:即使采用的临床试验没有强调任何统计学差异,以下文献综述显示,与传统的旋转骨手术相比,压电手术术后不适的减少令人鼓舞。然而,与传统的刺入相比,使用压电外科手术完成手术所需的时间更长。
{"title":"A split-mouth study comparing piezo electric surgery and traditional rotary burs on impacted third molars in young patients: an intraoperative and postoperative evaluation.","authors":"Francesca Zara,&nbsp;Claudio M De Sanctis,&nbsp;Fabia C Dede,&nbsp;Maurizio Bossù,&nbsp;Gian L Sfasciotti","doi":"10.23736/S0026-4970.20.04349-6","DOIUrl":"https://doi.org/10.23736/S0026-4970.20.04349-6","url":null,"abstract":"<p><strong>Background: </strong>Piezoelectric surgery has been used in many different medical fields, for instance it is used in the field of oral surgery, as a valuable alternative to traditional rotary burs. Its first use dates to 1975 by Horton even if the first effective device for use in dentistry, has been developed by Vercellotti after the year 2000. The hypothesis of this study is that piezosurgery technology is more suitable in terms of specific intra-operative and postoperative evaluations compared to the rotary technology in ostectomy for the avulsion of the third molar germ. The null hypothesis presented is the lack of significant differences between the two technologies after and during surgery.</p><p><strong>Methods: </strong>Intraoperative and postoperative aspects are evaluated for a comparison between traditional rotary instruments and piezosurgery during germectomies in young patients through a blind randomized study (split-mouth). The surgical technique to employ for each hemi-arch was randomly selected from a computer algorithm. Different criteria were considered during the surgical procedure, in order to compare the two techniques.</p><p><strong>Results: </strong>The piezoelectric technique demanded more time than traditional rotary method, and the difference was statistically significant both for the time of the entire procedure and the time only required for the ostectomy itself. Postoperative evaluations such as maximum mouth opening, facial swelling and postoperative pain showed no statistical difference.</p><p><strong>Conclusions: </strong>Even if the adopted clinical trial did not highlight any statistical difference the following review of literature showed an encouraging reduction in postoperative discomfort given by the piezosurgery as opposed to the traditional rotary bur surgery. The time taken to complete the operation, however, was longer with piezosurgery compared to traditional burs.</p>","PeriodicalId":18742,"journal":{"name":"Minerva stomatologica","volume":"69 5","pages":"278-285"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37934464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Comparison between four different implant surface debridement methods: an in-vitro experimental study. 四种不同种植体表面清创方法的体外实验研究。
Q3 Medicine Pub Date : 2020-10-01 DOI: 10.23736/S0026-4970.20.04342-3
Magda Mensi, Lorenzo Viviani, Raffaele Agosti, Eleonora Scotti, Gianluca Garzetti, Stefano Calza

Background: Peri-implantitis treatment is a very challenging topic to discuss. What is certain is that preventive/supportive therapy plays a key-role in peri-implant tissues' health maintenance and non-surgical implant surface mechanical debridement remains one of the solid pillars in the therapeutic pathway. In this perspective, many surface decontaminating methods have been proposed and tested to remove hard and soft bacterial deposits. The aim of this study was to compare four different commonly used non-surgical implant debridement methods in terms of cleaning potential in vitro, using a peri-implant pocket-simulating model.

Methods: Sixty-four dental implants were ink-stained and placed into a simulated peri-implant pocket. Samples were then divided into four groups and treated with different debridement methods: stainless-steel ultrasonic tip (PS), peek-coated ultrasonic tip (PI), sub-gingival air-polishing with erythritol powder (EHX) and sub-gingival air-polishing with glycine powder (GLY). For each treatment group, half of the samples were treated for 5 seconds and the other half for 45 seconds. High-resolution images were taken using a digital microscope and later analyzed with a light processing software for measuring the cleaned area percentage (ink-free). Two different images were captured for every sample: a first image with the implant positioned perpendicular to the microscope lenses (90°) and a second one with the implant placed with a 45° vertical angulation, with the smooth neck towards the ground. Percentage of removed ink was statistically modelled using a generalized linear mixed model with the implant as a random (clustering) factor.

Results: A paired comparison between all treatments in terms of debridement potential (cleaned area percentage) was performed. In 5s and with 90° sample angulation EHX/PS comparison showed an odds ratio of 2.75 (P<0.001), PI/EHX an OR of 0.20 (P<0.001), GLY/PS an OR of 2.90 (P<0.001), PI/GLY an OR of 0.19 (P<0.001) and PI/PS an OR of 0.56 (P=0.105). With the same sample angulation and 45s treatment time, the OR was 6.97 (P<0.001) for EHX/PS comparison, 0.14 (P<0.001) for PI/EHX comparison, 4.99 (P<0.001) for GLY/PS, 0.19 (P<0.001) for PI/GLY and 0.95 for PI/PS (P =0.989). With 5s of treatment time and 45° sample angulation, EHX/PS comparison shows a 3.19 odds ratio (P<0.001), PI/EHX a 0.14 odds ratio (P<0.001), GLY/PS a 3.06 odds ratio (P<0.001), PI/GLY a 0.15 odds ratio (P<0.001) and PI/PS a 0.46 odds ratio (P=0.017). With the same sample angulation but 45s treatment time, EHX/PS comparison produced an odds ratio of 4.90 (P<0.001), PI/EHX an OR of 0.20 (P<0.001), GLY/PS an OR of 8.74 (P<0.001), PI/GLY an OR of 0.11 (P<0.001) and PI/PS an OR 0.96 of (P =0.996).

Conclusions: Among the four treatments considered, air-polishing therapy represents the best one in terms of ink removal from the implant surface. F

背景:种植体周围炎的治疗是一个非常具有挑战性的话题。可以肯定的是,预防性/支持性治疗在种植体周围组织的健康维持中起着关键作用,非手术性种植体表面机械清创仍然是治疗途径中的坚实支柱之一。从这个角度来看,已经提出并测试了许多表面净化方法来去除硬的和软的细菌沉积物。本研究的目的是利用种植体周围口袋模拟模型,比较四种常用的非手术种植体清创方法在体外清洁潜力方面的差异。方法:64颗种植体染色后放置于模拟种植体周围口袋中。然后将样品分为四组,分别采用不同的清创方法:不锈钢超声针尖(PS)、peek-coated超声针尖(PI)、赤糖醇粉末龈下空气抛光(EHX)和甘氨酸粉末龈下空气抛光(GLY)。对于每个处理组,一半的样品处理5秒,另一半处理45秒。使用数码显微镜拍摄高分辨率图像,然后使用光处理软件进行分析,以测量清洁面积百分比(无油墨)。每个样本都捕获了两张不同的图像:第一张图像中植入物垂直于显微镜镜头(90°),第二张图像中植入物垂直角度为45°,颈部光滑朝向地面。使用广义线性混合模型对去除油墨的百分比进行统计建模,并将植入物作为随机(聚类)因素。结果:所有治疗方法在清创电位(清洁面积百分比)方面进行了配对比较。在5秒和90°样品角度时,ex /PS的比值比为2.75 (p)。结论:在所考虑的四种治疗方法中,空气抛光治疗在去除种植体表面墨迹方面效果最好。此外,将处理时间增加到45秒,空气抛光的效率大大提高。
{"title":"Comparison between four different implant surface debridement methods: an in-vitro experimental study.","authors":"Magda Mensi,&nbsp;Lorenzo Viviani,&nbsp;Raffaele Agosti,&nbsp;Eleonora Scotti,&nbsp;Gianluca Garzetti,&nbsp;Stefano Calza","doi":"10.23736/S0026-4970.20.04342-3","DOIUrl":"https://doi.org/10.23736/S0026-4970.20.04342-3","url":null,"abstract":"<p><strong>Background: </strong>Peri-implantitis treatment is a very challenging topic to discuss. What is certain is that preventive/supportive therapy plays a key-role in peri-implant tissues' health maintenance and non-surgical implant surface mechanical debridement remains one of the solid pillars in the therapeutic pathway. In this perspective, many surface decontaminating methods have been proposed and tested to remove hard and soft bacterial deposits. The aim of this study was to compare four different commonly used non-surgical implant debridement methods in terms of cleaning potential in vitro, using a peri-implant pocket-simulating model.</p><p><strong>Methods: </strong>Sixty-four dental implants were ink-stained and placed into a simulated peri-implant pocket. Samples were then divided into four groups and treated with different debridement methods: stainless-steel ultrasonic tip (PS), peek-coated ultrasonic tip (PI), sub-gingival air-polishing with erythritol powder (EHX) and sub-gingival air-polishing with glycine powder (GLY). For each treatment group, half of the samples were treated for 5 seconds and the other half for 45 seconds. High-resolution images were taken using a digital microscope and later analyzed with a light processing software for measuring the cleaned area percentage (ink-free). Two different images were captured for every sample: a first image with the implant positioned perpendicular to the microscope lenses (90°) and a second one with the implant placed with a 45° vertical angulation, with the smooth neck towards the ground. Percentage of removed ink was statistically modelled using a generalized linear mixed model with the implant as a random (clustering) factor.</p><p><strong>Results: </strong>A paired comparison between all treatments in terms of debridement potential (cleaned area percentage) was performed. In 5s and with 90° sample angulation EHX/PS comparison showed an odds ratio of 2.75 (P<0.001), PI/EHX an OR of 0.20 (P<0.001), GLY/PS an OR of 2.90 (P<0.001), PI/GLY an OR of 0.19 (P<0.001) and PI/PS an OR of 0.56 (P=0.105). With the same sample angulation and 45s treatment time, the OR was 6.97 (P<0.001) for EHX/PS comparison, 0.14 (P<0.001) for PI/EHX comparison, 4.99 (P<0.001) for GLY/PS, 0.19 (P<0.001) for PI/GLY and 0.95 for PI/PS (P =0.989). With 5s of treatment time and 45° sample angulation, EHX/PS comparison shows a 3.19 odds ratio (P<0.001), PI/EHX a 0.14 odds ratio (P<0.001), GLY/PS a 3.06 odds ratio (P<0.001), PI/GLY a 0.15 odds ratio (P<0.001) and PI/PS a 0.46 odds ratio (P=0.017). With the same sample angulation but 45s treatment time, EHX/PS comparison produced an odds ratio of 4.90 (P<0.001), PI/EHX an OR of 0.20 (P<0.001), GLY/PS an OR of 8.74 (P<0.001), PI/GLY an OR of 0.11 (P<0.001) and PI/PS an OR 0.96 of (P =0.996).</p><p><strong>Conclusions: </strong>Among the four treatments considered, air-polishing therapy represents the best one in terms of ink removal from the implant surface. F","PeriodicalId":18742,"journal":{"name":"Minerva stomatologica","volume":"69 5","pages":"286-294"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38596650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Transcortical bone capillary vessels network: implication on the maxillofacial district. 经皮质骨毛细血管网络:对颌面区的影响。
Q3 Medicine Pub Date : 2020-10-01 Epub Date: 2020-05-14 DOI: 10.23736/S0026-4970.20.04294-6
Luca Fiorillo, Gabriele Cervino, Diana Russo, Annalisa Itro, Luigi Laino, Marco Cicciù

Introduction: The field of medicine takes steps forward every day. Although some aspects of our organism seem clear, scientific discoveries also affect fields such as anatomy. Recently, transcortical vessels (TCVs) have been debated, although it was thought that cortical bones were not interested by these structures. This would upset some concepts of oral surgery, maxillofacial surgery, periodontics and implantology.

Evidence acqusition: In this study an analysis of the literature on this topic was carried out, and it is proposed to understand the possible implications of TCVs to the oral health.

Evidence synthesis: Being a current topic, the aim of the study is to promote research in this field, leading to the evidence of these anatomical structures in the maxillofacial district. This study is of a prospective type, there are no other results that speak of these vessels in the maxillofacial district, waiting for a histological study.

Conclusions: The purpose of the study, therefore, is to shed light on this topic, so that the research could move in this direction.

医学领域每天都在向前发展。虽然我们有机体的某些方面似乎很清楚,但科学发现也会影响解剖学等领域。近来,关于皮质血管(transccortical vessel, TCVs)的研究一直存在争议,尽管人们认为皮质骨对这些结构不感兴趣。这会颠覆口腔外科、颌面外科、牙周学和种植学的一些概念。证据获取:本研究对有关该主题的文献进行了分析,并提出了解TCVs对口腔健康的可能影响。证据合成:作为一个当前的课题,本研究的目的是促进该领域的研究,导致这些颌面区解剖结构的证据。本研究为前瞻性研究,没有其他结果表明这些血管位于颌面区,有待组织学研究。结论:因此,本研究的目的是阐明这一主题,使研究能够朝着这个方向发展。
{"title":"Transcortical bone capillary vessels network: implication on the maxillofacial district.","authors":"Luca Fiorillo,&nbsp;Gabriele Cervino,&nbsp;Diana Russo,&nbsp;Annalisa Itro,&nbsp;Luigi Laino,&nbsp;Marco Cicciù","doi":"10.23736/S0026-4970.20.04294-6","DOIUrl":"https://doi.org/10.23736/S0026-4970.20.04294-6","url":null,"abstract":"<p><strong>Introduction: </strong>The field of medicine takes steps forward every day. Although some aspects of our organism seem clear, scientific discoveries also affect fields such as anatomy. Recently, transcortical vessels (TCVs) have been debated, although it was thought that cortical bones were not interested by these structures. This would upset some concepts of oral surgery, maxillofacial surgery, periodontics and implantology.</p><p><strong>Evidence acqusition: </strong>In this study an analysis of the literature on this topic was carried out, and it is proposed to understand the possible implications of TCVs to the oral health.</p><p><strong>Evidence synthesis: </strong>Being a current topic, the aim of the study is to promote research in this field, leading to the evidence of these anatomical structures in the maxillofacial district. This study is of a prospective type, there are no other results that speak of these vessels in the maxillofacial district, waiting for a histological study.</p><p><strong>Conclusions: </strong>The purpose of the study, therefore, is to shed light on this topic, so that the research could move in this direction.</p>","PeriodicalId":18742,"journal":{"name":"Minerva stomatologica","volume":"69 5","pages":"309-316"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37933973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Tissue level implants in healthy versus medically compromised patients: a cohort comparative study. 健康与医学受损患者的组织水平植入物:一项队列比较研究
Q3 Medicine Pub Date : 2020-10-01 Epub Date: 2020-05-14 DOI: 10.23736/S0026-4970.20.04359-9
Vincenzo Marchio, Giacomo Derchi, Chiara Cinquini, Marco Miceli, Mario Gabriele, Fortunato Alfonsi, Antonio Barone

Background: Dental implants placed in medically compromised patients have predictable outcomes and a high rate of survival, compared to those placed in healthy patients. The aims of this study were to observe and compare implant survival/success rates and soft tissue response to tissue-level implants placed in healthy and medically compromised patients with a 1-year follow-up.

Methods: Seventy-two patients, 36 healthy patients (20 females and 16 males) and 36 medically compromised patients (18 females and 18 males) affected by cardiovascular diseases (arrythmia, hypertension, atrial fibrillation, bypass and pacemaker surgery), depression, endocrine metabolic diseases (hypercholesterolemia, type II diabetes, Hashimoto's thyroiditis), gastrointestinal diseases (gastritis, hiatal hernia, gastric ulcers), asthma, osteoporosis or glaucoma received one tissue-level implant. Measurements for primary and secondary outcomes were collected immediately after implant placement and at 1 year from implant insertion.

Results: Three were failed and two were survived out of a total of 72 implants. Among healthy patients, two implants failed while one was classified as survived; among Medically compromised patients one implant failed and another one was classified as survived. No statistically significant difference was found between the two groups in terms of success rate or survival rate. No statistically significant differences between the two groups' marginal bone level was observed. In healthy patients a mean loss of keratinized tissue (-0.1±0.6 mm) was reported, while in medically compromised patients a mean gain was reported (+0.5±0.8 mm).

Conclusions: In terms of success, failure and survival rates, tissue level implants placed in healthy and in medically compromised individuals showed no short-term (1 year) differences.

背景:与健康患者相比,在医学上受损的患者中植入牙种植体具有可预测的结果和高存活率。本研究的目的是通过1年的随访观察和比较健康和医学受损患者对组织级植入物的存活/成功率和软组织反应。方法:72名患者,36名健康患者(20名女性,16名男性)和36名医学上有问题的患者(18名女性,18名男性),分别患有心血管疾病(心律失常,高血压,心房颤动,旁路手术和起搏器手术),抑郁症,内分泌代谢疾病(高胆固醇血症,II型糖尿病,桥本甲状腺炎),胃肠道疾病(胃炎,裂孔疝,胃溃疡),哮喘,骨质疏松症或青光眼,接受了一次组织水平的植入。在植入种植体后立即和植入种植体后1年收集主要和次要结果的测量数据。结果:72例种植体中3例失败,2例存活。在健康患者中,2例植入失败,1例存活;在医学上受损的患者中,一个植入失败,另一个被归类为存活。两组在成功率和生存率方面无统计学差异。两组边缘骨水平差异无统计学意义。在健康患者中,角化组织平均损失(-0.1±0.6 mm),而在医学上受损的患者中,平均增加(+0.5±0.8 mm)。结论:在成功、失败和存活率方面,健康个体和医学受损个体的组织水平植入物没有短期(1年)差异。
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引用次数: 1
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Minerva stomatologica
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