Aims and objectives: This study aims to assess and compare the incidence and rate of oral candidal colonization in patients with cleft lip and palate and collate it with healthy individuals. The objectives of this study were to evaluate the factors that may affect the incidence, rate, and polycolonity of colonization of oral Candida species in patients with cleft lip and palate (CLP) as compared to healthy individuals.
Materials and methods: The current prospective study involved the collection and assessment of oral samples from 50 CLP patients and compared it with oral samples from 50 healthy individuals. Colonies of Candida albicans and other Candida species were identified by using germ tube test and differential chromogenic media. Assessment of the distribution trend of various Candida species and their variation based on age, gender, type of cleft, number of surgeries, and oral hygiene status were recorded.
Results: A highly significant (P value < 0.001) statistical difference was seen in the oral carriage rate of Candida species between the two groups with values more in the study group (60.75 ± 71.43) than in controls (1.62 ± 2.22). Individually comparing the different Candida species, significant difference in presence of C albicans (P value = 0.004), C parapsilosis (P value = 0.015), and C dubliensis (P value = 0.027) was seen as compared to other species. In the context of the type of cleft and the presence of Candida species Candida albicans was the most prevalent in patients with the cleft alveolus (60.0% n = 15), unilateral CLP (66.7% n = 8), and bilateral CLP (100.0% n = 3) respectively. Nonsignificant variation in prevalence was seen in the various fungal species based on an individual's gender and oral hygiene and the number of surgeries status was observed.
Conclusion: The anatomical alteration in the oral cavity of patients with CLP contributes to the high incidence and prevalence of Candida species.
Objective: The aim of the present study is to evaluate the relationship of gingival biotype in different malocclusions.
Methods: A total of 157 periodontally healthy subjects (88 males and 69 females) were enrolled in this cross-sectional study. The study participants were divided into three groups of skeletal class I, class II, and class III. The probe transparency method was used to determine the quality and gingival tissue into thick and thin biotype.
Results: There was significant difference in gingival biotype among different skeletal malocclusion with high prevalence of thin gingival biotype in class I subjects and more prevalence of thick biotype in class II and class III individuals (P-value: 0.022). Pairwise comparison of gingival biotype in class I versus class II showed significant difference (P-value: 0.032); however in class I versus class III and class II versus class III, the test result was nonsignificant. The overall frequency of thin gingival biotype was significantly less in female subjects with respect to males (P-value: 0.025).
Conclusion: A significant relationship is present between skeletal malocclusion and quality of gingival biotype. The prevalence of thick gingival biotype is found more in females as compared to male individuals. The thin gingival biotype is more commonly seen in skeletal class I than class II and class III.
Introduction: Uniplanar devices have been criticized for being insufficient to correct complex mandibular deformities and associated problems of open bite and cross bite. The use of oblique vector to correct complex multiplanar deformities using uniplanar mandibular distraction devices is the uniqueness of the present case series.
Aim and objective: The aim of the present case series is to describe the successful use of uniplanar mandibular distraction devices for the correction of complex multiplanar deformities.
Material and method: The technique of callous molding was employed to overcome any open bite. A total of 40 mandibular distractors in 20 patients (mean age 13 ± 2.67 years) were placed on the mandible for correction of the facial deformity associated with the lower jaw(mandible) in vertical, horizontal and/or sagittal plane, secondary to temporomandibular joint ankylosis. The distraction was done before and after the gap arthroplasty in 15 and 5 patients, respectively. A latency period of 3-5 days was applied, and distraction was performed at a rate of 1 mm/day with the rhythm of 0.5 mm twice daily.
Results: The significant lengthening was observed in both mandibular height (Ar Go) (50.40 ± 1.52 mm from 38.80 ± 4.38mm, P = 0.006) as well as in mandibular corpus length (Go Pg) (79.40 ± 2.28 from 58.80 ± 4.09, P = 0.001). Statistically significant changes in mandibular dimensions, facial proportions, and soft tissue profile were seen, which was assessed with the help of COGS analysis done on lateral cephalogram taken preoperatively and postoperatively.
Conclusion: With intelligent vector planning and callus molding multiplanar complex deformities can be corrected by using semiburieduniplanar devices.
Oral Lichen Planus (OLP), an autoimmune disorder of unclear pathogenesis affects quality of life of affected individual. Intervention regimens are multiple and still evolving due to its resistance to recover and ability to recur. Platelet rich Plasma (PRP) is a newer, promising treatment modality tested by researchers because of its low cost and negligible adverse effects. Articles were retrieved from search engines of PubMed / Medline, Scopus and Web of Science which fulfilled the eligibility criteria. Cochrane risk of bias tool assessed quality of clinical studies and Joanna Briggs Institute for case reports. A total of 4 articles were included for the systematic review, of which 2 are clinical trials and 2 case reports. All cases were of erosive nature. PRP in case reports were administered when patients did not respond to conventional therapy. PRP demonstrated effective therapeutic benefit in regards to outcome of pain and lesion appearance. PRP can be considered as a potential alternative therapy in treating non-responsive OLP. Further studies are recommended to arrive at a definitive conclusion.
Background: The treatment of osseous bone defects created following enucleation of a cyst is an arduous challenge. Autogenous bone grafts despite being the gold standard have various drawbacks such as donor site morbidity, limited availability of bone graft, and increased operative time. Hence, there are various bone grafts which are being investigated which could overcome the limitations of autografts. Thus, this study was conducted to evaluate the efficacy of calcium sulfate (CS), a bone graft substitute, for spontaneous bone regeneration of cystic defects.
Objectives: The purpose of this study is to evaluate bone formation in odontogenic cystic defects following enucleation and reconstruction with bone graft substitute by three-dimensional radiographic and clinical evaluation.
Methodology: A total of twenty patients diagnosed with odontogenic cysts were randomly divided into two groups, out of which the study group had undergone enucleation with bone grafting (tobramycin-impregnated CS dihydrate) and the control group had undergone enucleation without bone grafting. The patients were evaluated clinically and radiographically at the 1st, 3rd, 6th, and 12th months postoperatively.
Results: There was no bone formation observed at 1 month postoperative in both the groups. There was a statistically significant higher bone defect reduction observed radiologically on orthopantomogram and computed tomography scan in the study group than the control group at the 3rd, 6th, and 12th months postoperative. The rate of reduction in cystic volume of the study group at the 12th month was 94.4% and in the control group was 37.16%.
Conclusion: Immediate grafting of cystic cavity can avoid complications such as pathological fracture due to less bone support, delayed healing, etc., The utilization of a graft with a property of inducing rapid bone formation should be taken into consideration. The use of CS as a grafting material accelerated the rate of bone regeneration in the cystic defects, with minimal complications.