Pub Date : 2024-12-17DOI: 10.1038/s43018-024-00856-4
Vincenzo Giacco
{"title":"Radioligand cancer therapy comes to the fore","authors":"Vincenzo Giacco","doi":"10.1038/s43018-024-00856-4","DOIUrl":"10.1038/s43018-024-00856-4","url":null,"abstract":"","PeriodicalId":18885,"journal":{"name":"Nature cancer","volume":"5 12","pages":"1782-1782"},"PeriodicalIF":23.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-17DOI: 10.1038/s43018-024-00857-3
Melanie Senior
AI promises to create medicines faster, more cheaply, and with greater precision. Despite attracting big sums and splashy headlines, AI-powered biotechs have yet to get a product over the finish line. Where is AI’s greatest impact so far?
{"title":"Beyond the hype of AI in cancer R&D","authors":"Melanie Senior","doi":"10.1038/s43018-024-00857-3","DOIUrl":"10.1038/s43018-024-00857-3","url":null,"abstract":"AI promises to create medicines faster, more cheaply, and with greater precision. Despite attracting big sums and splashy headlines, AI-powered biotechs have yet to get a product over the finish line. Where is AI’s greatest impact so far?","PeriodicalId":18885,"journal":{"name":"Nature cancer","volume":"5 12","pages":"1759-1761"},"PeriodicalIF":23.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-17DOI: 10.1038/s43018-024-00832-y
Ioanna Pavlaki
{"title":"Mini colons to study cancer ex vivo","authors":"Ioanna Pavlaki","doi":"10.1038/s43018-024-00832-y","DOIUrl":"10.1038/s43018-024-00832-y","url":null,"abstract":"","PeriodicalId":18885,"journal":{"name":"Nature cancer","volume":"5 12","pages":"1786-1786"},"PeriodicalIF":23.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-17DOI: 10.1038/s43018-024-00836-8
Tiffanie Chouleur
{"title":"Closing the gaps in cancer genomic disparities","authors":"Tiffanie Chouleur","doi":"10.1038/s43018-024-00836-8","DOIUrl":"10.1038/s43018-024-00836-8","url":null,"abstract":"","PeriodicalId":18885,"journal":{"name":"Nature cancer","volume":"5 12","pages":"1785-1785"},"PeriodicalIF":23.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-17DOI: 10.1038/s43018-024-00868-0
Cameron Walker, Michael Angelo
Spatial-omics tools, together with deep learning models, are revealing interactions between tumors and their environment, including immune cells, and are aiding human-like performance in histopathological analysis, with the potential to improve diagnostic accuracy and treatment choices.
{"title":"Toward clinical applications of spatial-omics in cancer research","authors":"Cameron Walker, Michael Angelo","doi":"10.1038/s43018-024-00868-0","DOIUrl":"10.1038/s43018-024-00868-0","url":null,"abstract":"Spatial-omics tools, together with deep learning models, are revealing interactions between tumors and their environment, including immune cells, and are aiding human-like performance in histopathological analysis, with the potential to improve diagnostic accuracy and treatment choices.","PeriodicalId":18885,"journal":{"name":"Nature cancer","volume":"5 12","pages":"1771-1773"},"PeriodicalIF":23.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-17DOI: 10.1038/s43018-024-00834-w
Julieta Alfonso
{"title":"Adjusting the clock for cancer immunotherapy","authors":"Julieta Alfonso","doi":"10.1038/s43018-024-00834-w","DOIUrl":"10.1038/s43018-024-00834-w","url":null,"abstract":"","PeriodicalId":18885,"journal":{"name":"Nature cancer","volume":"5 12","pages":"1781-1781"},"PeriodicalIF":23.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-17DOI: 10.1038/s43018-024-00867-1
Céline Grégoire, J. Joseph Melenhorst
Chimeric antigen receptor (CAR)-T cells have revolutionized the treatment of hematological malignancies; however long-term safety concerns, associated with infections and secondary malignancies, have been reported. Here we discuss the clinical challenges of CAR-T cell therapy in light of this emerging benefit–risk controversy.
{"title":"Navigating CAR-T cell therapy long-term complications","authors":"Céline Grégoire, J. Joseph Melenhorst","doi":"10.1038/s43018-024-00867-1","DOIUrl":"10.1038/s43018-024-00867-1","url":null,"abstract":"Chimeric antigen receptor (CAR)-T cells have revolutionized the treatment of hematological malignancies; however long-term safety concerns, associated with infections and secondary malignancies, have been reported. Here we discuss the clinical challenges of CAR-T cell therapy in light of this emerging benefit–risk controversy.","PeriodicalId":18885,"journal":{"name":"Nature cancer","volume":"5 12","pages":"1768-1770"},"PeriodicalIF":23.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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