首页 > 最新文献

Nature Reviews. Drug Discovery最新文献

英文 中文
Combination therapy alleviates AD-related pathologies 联合治疗可减轻ad相关病理
IF 101.8 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Nature Reviews. Drug Discovery
Pub Date : 2025-09-03 DOI: 10.1038/d41573-025-00146-3
Sarah Crunkhorn
{"title":"Combination therapy alleviates AD-related pathologies","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00146-3","DOIUrl":"10.1038/d41573-025-00146-3","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"742-742"},"PeriodicalIF":101.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Towards a broad-spectrum antiviral agent 研制广谱抗病毒药物
IF 101.8 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Nature Reviews. Drug Discovery
Pub Date : 2025-09-03 DOI: 10.1038/d41573-025-00145-4
Sarah Crunkhorn
{"title":"Towards a broad-spectrum antiviral agent","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00145-4","DOIUrl":"10.1038/d41573-025-00145-4","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"742-742"},"PeriodicalIF":101.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potentiating the integrated stress response 增强综合应力反应
IF 101.8 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Nature Reviews. Drug Discovery
Pub Date : 2025-09-03 DOI: 10.1038/d41573-025-00147-2
Sarah Crunkhorn
{"title":"Potentiating the integrated stress response","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00147-2","DOIUrl":"10.1038/d41573-025-00147-2","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"742-742"},"PeriodicalIF":101.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prime editing treats childhood neurological disease 主要编辑治疗儿童神经系统疾病
IF 101.8 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Nature Reviews. Drug Discovery
Pub Date : 2025-09-03 DOI: 10.1038/d41573-025-00144-5
Sarah Crunkhorn
{"title":"Prime editing treats childhood neurological disease","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00144-5","DOIUrl":"10.1038/d41573-025-00144-5","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"742-742"},"PeriodicalIF":101.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Soluble Notch agonists drive T cell production 可溶性Notch激动剂驱动T细胞生成
IF 101.8 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Nature Reviews. Drug Discovery
Pub Date : 2025-09-02 DOI: 10.1038/d41573-025-00143-6
M. Teresa Villanueva
{"title":"Soluble Notch agonists drive T cell production","authors":"M. Teresa Villanueva","doi":"10.1038/d41573-025-00143-6","DOIUrl":"10.1038/d41573-025-00143-6","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"741-741"},"PeriodicalIF":101.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144928591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epigenetic inhibitor silences KRAS-driven oncogenes 表观遗传抑制剂沉默kras驱动的癌基因
IF 101.8 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Nature Reviews. Drug Discovery
Pub Date : 2025-08-28 DOI: 10.1038/d41573-025-00142-7
Alex Eccleston
{"title":"Epigenetic inhibitor silences KRAS-driven oncogenes","authors":"Alex Eccleston","doi":"10.1038/d41573-025-00142-7","DOIUrl":"10.1038/d41573-025-00142-7","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"740-740"},"PeriodicalIF":101.8,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144911025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transport vehicle delivers antibodies to the brain 运输工具将抗体运送到大脑
IF 101.8 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Nature Reviews. Drug Discovery
Pub Date : 2025-08-27 DOI: 10.1038/d41573-025-00140-9
Katie Kingwell
{"title":"Transport vehicle delivers antibodies to the brain","authors":"Katie Kingwell","doi":"10.1038/d41573-025-00140-9","DOIUrl":"10.1038/d41573-025-00140-9","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"740-740"},"PeriodicalIF":101.8,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gut microbiota–derived metabolite drives atherosclerosis 肠道微生物衍生代谢物驱动动脉粥样硬化
IF 101.8 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Nature Reviews. Drug Discovery
Pub Date : 2025-08-27 DOI: 10.1038/d41573-025-00141-8
Sarah Crunkhorn
{"title":"Gut microbiota–derived metabolite drives atherosclerosis","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-025-00141-8","DOIUrl":"10.1038/d41573-025-00141-8","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"741-741"},"PeriodicalIF":101.8,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From gene hunter to drug hunter 从基因猎人到药物猎人
IF 101.8 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Nature Reviews. Drug Discovery
Pub Date : 2025-08-14 DOI: 10.1038/d41573-025-00139-2
Asher Mullard
Howard Chang, Amgen’s new CSO, discusses genetic target discovery, extrachromosomal DNA and technology development. Howard Chang, Amgen’s new CSO, discusses genetic target discovery, extrachromosomal DNA and technology development.
Howard Chang，安进的新CSO，讨论基因靶点的发现，染色体外DNA和技术的发展。
{"title":"From gene hunter to drug hunter","authors":"Asher Mullard","doi":"10.1038/d41573-025-00139-2","DOIUrl":"10.1038/d41573-025-00139-2","url":null,"abstract":"Howard Chang, Amgen’s new CSO, discusses genetic target discovery, extrachromosomal DNA and technology development. Howard Chang, Amgen’s new CSO, discusses genetic target discovery, extrachromosomal DNA and technology development.","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 9","pages":"658-659"},"PeriodicalIF":101.8,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-025-00139-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144839988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neutrophil-targeted drug secures first FDA approval for inflammatory lung disease 中性粒细胞靶向药物首次获得FDA批准用于炎症性肺病
IF 101.8 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Nature Reviews. Drug Discovery
Pub Date : 2025-08-12 DOI: 10.1038/d41573-025-00135-6
Katie Kingwell
{"title":"Neutrophil-targeted drug secures first FDA approval for inflammatory lung disease","authors":"Katie Kingwell","doi":"10.1038/d41573-025-00135-6","DOIUrl":"10.1038/d41573-025-00135-6","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 10","pages":"729-729"},"PeriodicalIF":101.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/d41573-025-00135-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144826021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页
类型
全部 化学•材料 生命科学 医学 物理 工程技术 环境•农林 材料科学 地球科学 法学 管理学 化学 环境科学与生态学 计算机科学 教育学 经济学 农林科学 人文科学 生物学 数学 物理与天体物理 心理学 综合性期刊 其他 工业工程 理学 历史学 农学 文学 信息工程
数据库
全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley
期刊
Nature Reviews. Drug Discovery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
﹀
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们：info@booksci.cn
Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1