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Nature Reviews. Drug Discovery最新文献

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NaV1.8 inhibitor poised to provide opioid-free pain relief NaV1.8抑制剂有望提供无阿片类药物疼痛缓解
IF 122.7 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Pub Date : 2024-12-12 DOI: 10.1038/d41573-024-00203-3
Katie Kingwell
Vertex’s first-in-class suzetrigine could soon usher in a new class of analgesic. Vertex’s first-in-class suzetrigine could soon usher in a new class of analgesic.
Vertex的同类首创的suzetriine可能很快就会引领一种新的镇痛药。
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引用次数: 0
Upcoming FDA approval decisions in Q1 2025 FDA将于2025年第一季度做出批准决定
IF 122.7 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Pub Date : 2024-12-11 DOI: 10.1038/d41573-024-00202-4
Kaniaw Dilzer
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引用次数: 0
Top product forecasts for 2025 2025年的顶级产品预测
IF 122.7 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Pub Date : 2024-12-10 DOI: 10.1038/d41573-024-00199-w
Paul Verdin
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引用次数: 0
Can non-canonical amino acids open up non-canonical drug discovery opportunities? 非规范氨基酸能打开非规范药物发现的机会吗?
IF 122.7 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Pub Date : 2024-12-09 DOI: 10.1038/d41573-024-00201-5
Asher Mullard
Jason Chin, head of Cambridge’s Centre for Chemical & Synthetic Biology and CSO of Constructive Bio, discusses the role for unnatural amino acids in biologic therapies. Jason Chin, head of Cambridge’s Centre for Chemical & Synthetic Biology and CSO of Constructive Bio, discusses the role for unnatural amino acids in biologic therapies.
剑桥大学化学与合成生物学中心主任兼建设性生物技术首席执行官Jason Chin讨论了非天然氨基酸在生物治疗中的作用。
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引用次数: 0
Showing tau the exit 显示出口
IF 122.7 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Pub Date : 2024-12-05 DOI: 10.1038/d41573-024-00200-6
M. Teresa Villanueva
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引用次数: 0
Covalent inhibitor engages oncogenic AKT kinase 共价抑制剂参与致癌AKT激酶
IF 122.7 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Pub Date : 2024-12-03 DOI: 10.1038/d41573-024-00197-y
Alex Eccleston
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引用次数: 0
FDA approves first menin inhibitor, for acute leukaemia FDA批准首个治疗急性白血病的menin抑制剂
IF 122.7 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Pub Date : 2024-12-03 DOI: 10.1038/d41573-024-00198-x
Asher Mullard
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引用次数: 0
Multi-TACs target solid tumours 针对实体瘤的 Multi-TACs
IF 122.7 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Pub Date : 2024-11-27 DOI: 10.1038/d41573-024-00193-2
Sarah Crunkhorn
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引用次数: 0
Understanding cholestatic itch 了解胆汁淤积性瘙痒
IF 122.7 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Pub Date : 2024-11-27 DOI: 10.1038/d41573-024-00191-4
Sarah Crunkhorn
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引用次数: 0
ENGases to treat IgG-mediated diseases 治疗 IgG 媒介疾病的 ENGases
IF 122.7 1区 医学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Pub Date : 2024-11-27 DOI: 10.1038/d41573-024-00190-5
Sarah Crunkhorn
{"title":"ENGases to treat IgG-mediated diseases","authors":"Sarah Crunkhorn","doi":"10.1038/d41573-024-00190-5","DOIUrl":"10.1038/d41573-024-00190-5","url":null,"abstract":"","PeriodicalId":19068,"journal":{"name":"Nature Reviews. Drug Discovery","volume":"24 1","pages":"17-17"},"PeriodicalIF":122.7,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142718291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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