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Robotic surgery for microvascular decompression in hemifacial spasm: a feasibility study 机器人手术为半面痉挛患者的微血管减压:一项可行性研究
Pub Date : 2024-04-05 DOI: 10.52662/nf.2023.00108
H. Ji, Min Ho Lee, Tae-Kyu Lee
Objective: The gold-standard treatment modality for hemifacial spasm is micro-vascular decompression (MVD) via microsurgery. Recently, endoscopic surgery has been attempted by many surgeons. The present study investigated the feasibility of robotic surgery for MVD to treat hemifacial spasm. Methods: The study was conducted using the da Vinci Xi model, and a three-dimensional model was purchased and applied. The advantages and disadvantages of microsurgery, endoscopic surgery, and robotic surgery were compared. Results: In robotic surgery, the root exit zone can be viewed from various angles by magnifying it, similarly to the endoscope and better than the microscope. However, there is a limit to performing versatile manipulations because various tools are not available. When robotic surgery is used, the camera can be applied more stably and compensate for any tremor in the surgeon’s hand, likely making surgery safer. Conclusion: Currently, the approaches for MVD using robotic surgery are limited in their application. However, when optimal tools are developed, it is expected that they can be applied as an effective treatment modality for MVD to treat hemifacial spasm.
目的:半面痉挛的金标准治疗方法是通过显微手术进行微血管减压(MVD)。最近,许多外科医生开始尝试内窥镜手术。本研究探讨了机器人手术 MVD 治疗半面痉挛的可行性。方法:研究使用达芬奇Xi模型进行,并购买和应用了三维模型。比较了显微手术、内窥镜手术和机器人手术的优缺点。结果显示在机器人手术中,通过放大可从不同角度观察牙根出口区,与内窥镜类似,优于显微镜。但是,由于没有各种工具,在进行多功能操作时会受到限制。使用机器人手术时,照相机可以更稳定地使用,并能补偿外科医生手部的震颤,从而使手术更安全。结论目前,使用机器人手术治疗子宫内膜异位症的方法应用有限。然而,当开发出最佳工具后,有望将其作为一种有效的 MVD 治疗方式应用于治疗半面痉挛。
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引用次数: 0
Stereotactic brain biopsy of John Cunningham virus-polymerase chain reaction-negative progressive multifocal leukoencephalopathy: a case report 约翰-坎宁安病毒聚合酶链反应阴性进行性多灶性白质脑病的立体定向脑活检:病例报告
Pub Date : 2024-03-12 DOI: 10.52662/jksfn.2023.00087
Sae Jun Ahn, Jong Chan Lee, Won Seok Chang, Seung Woo Hong
Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease of the central nervous system caused by the
进行性多灶性白质脑病(PML)是一种罕见的中枢神经系统脱髓鞘疾病,其病因是
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引用次数: 0
Changes in theta and gamma oscillations of the medial prefrontal cortex following hippocampal-focused ultrasound stimulation 海马聚焦超声刺激后内侧前额叶皮层θ和γ振荡的变化
Pub Date : 2024-03-07 DOI: 10.52662/jksfn.2023.00094
Jiwon Baek, Younghee Seo, Bong-Soo Kim, Young Cheol Na, Won Seok Chang
Objective: Neuromodulation is a rapidly growing field of treatment, encompassing implantable and noninvasive technology-based approaches. Focused ultrasound (FUS), a noninvasive method, has the potential to modulate neural activity in deep brain regions with spatial precision based on the penetrance of sound waves into the bone and soft tissue. However, neuromodulation is limited by the inability to confirm modulation in real-time. Electrophysiological technology is required to overcome this limitation. In this study, we aimed to confirm neural activity using Neuropixel electrodes during FUS sonication. Methods: Six male C57BL/6 mice were subjected to ultrasound sonication in the hippocampus. Simultaneously, local field potential (LFP) measurements were performed using Neuropixel electrodes. The experimental groups were divided into three categories: before, during, and after FUS sonication and the measured LFP data were compared between groups. Results: Theta and gamma waves were extracted from the recorded LFP data and compared between the groups. The theta and gamma oscillations changed after FUS sonication compared to before. The theta graph showed significant changes between the pre-and during-treatment groups and between the during-and post-treatment groups (theta: 4–8 Hz, F=23.91, p<0.0001). However, the gamma graph did not show significant changes in any groups (gamma: 30–50 Hz). Additionally, the expression of c-fos, a marker of neuronal activity, increased after FUS sonication. Conclusion: Although further research is needed—including longer follow-up LFP measurements after FUS sonication and the collection of more LFP data— neuromodulation with FUS can be considered usable in other neurological disease models.
目的:神经调控是一个快速发展的治疗领域,包括植入式和非侵入式技术方法。聚焦超声(FUS)是一种非侵入性方法,它可以根据声波对骨骼和软组织的穿透力,在空间上精确调节大脑深部区域的神经活动。然而,神经调制因无法实时确认调制而受到限制。要克服这一局限,需要电生理技术。本研究旨在使用 Neuropixel 电极确认 FUS 声波治疗过程中的神经活动。研究方法对六只雄性 C57BL/6 小鼠的海马进行超声波治疗。同时使用 Neuropixel 电极进行局部场电位(LFP)测量。实验组被分为三类:FUS超声治疗前、治疗中和治疗后,并对各组的LFP测量数据进行比较。结果从记录的 LFP 数据中提取了θ波和γ波,并进行了组间比较。FUS 声波治疗后,θ 波和γ 波的振荡与治疗前相比发生了变化。θ波图在治疗前和治疗期间组之间以及治疗期间和治疗后组之间均有显著变化(θ波:4-8赫兹,F=23.91,P<0.0001)。然而,伽马图在任何组别中都未显示出显著变化(伽马:30-50 赫兹)。此外,神经元活动标志物 c-fos 的表达在 FUS 声波处理后有所增加。结论尽管还需要进一步的研究--包括在 FUS 声波治疗后进行更长时间的 LFP 随访测量和收集更多的 LFP 数据--但可以考虑将 FUS 神经调控用于其他神经疾病模型。
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引用次数: 0
The first treatment option for secondary trigeminal neuralgia: open surgery versus stereotactic radiosurgery 继发性三叉神经痛的第一种治疗选择:开放手术与立体定向放射手术
Pub Date : 2023-09-08 DOI: 10.52662/jksfn.2023.00066
Yoohyun Kwon, H. Roh, Jong Hyun Kim
This
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引用次数: 0
Fahr disease presenting with multiple cerebral calcifications Fahr病表现为多发性脑钙化
Pub Date : 2023-06-30 DOI: 10.52662/jksfn.2023.00038
Hyung mo Goo, Sang-Youl Yoon, Seong-Hyun Park
Fahr disease, also known as idiopathic basal ganglion calcification, is a rare and genetically heterogeneous neurological disorder. Herein, we report a rare case of Fahr disease presenting with multiple cerebral calcifications. A 63-year-old woman presented with dizziness to a local clinic. Brain computed tomography performed on admission revealed multiple high-intensity lesions in both basal ganglia, both cerebellar hemispheres, and the left frontal lobe. In contrast, brain magnetic resonance imaging (MRI) showed no prominent lesions on T2- and T1-weighted images, and there was no contrast enhancement after gadolinium injection. However, multiple dark signals were detected on gradient echo MRI. The location and radiological appearance of the lesion resembled those of a physiological intracranial calcification, except for asymmetric calcification in both cerebellar hemispheres and the left frontal subcortical white matter. The patient was diagnosed with basal ganglion calcification with multiple cerebral cavernous malformations or, less likely, brain tumors. Through a careful radiological and clinical review, the calcifications were diagnosed as Fahr disease. Follow-up was planned. It is important to consider the presence of multiple intracranial calcifications in the basal ganglia, cerebellum, or deep subcortical white matter as a warning sign for Fahr disease.
Fahr病,又称特发性基底神经节钙化,是一种罕见的遗传异质性神经系统疾病。在此,我们报告一例罕见的Fahr疾病,表现为多发性脑钙化。一名63岁妇女因头晕到当地诊所就诊。入院时进行的脑部计算机断层扫描显示双侧基底节区、双侧小脑半球和左额叶多发高强度病变。相反,脑磁共振成像(MRI)在T2和t1加权图像上未见明显病变,注射钆后未见对比增强。然而,梯度回波MRI检测到多个暗信号。除了小脑半球和左额叶皮层下白质的不对称钙化外,病变的位置和影像学表现与生理性颅内钙化相似。该患者被诊断为基底神经节钙化并多发性脑海绵状畸形,或者不太可能是脑肿瘤。通过仔细的影像学和临床检查,钙化被诊断为Fahr病。计划了后续行动。在基底节区、小脑或皮层下深部白质出现多发性颅内钙化是Fahr病的一个重要警告信号。
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引用次数: 0
Huge occipital spindle cell lipoma: a case report 枕骨巨大梭形细胞脂肪瘤1例
Pub Date : 2023-06-30 DOI: 10.52662/jksfn.2023.00010
Kyung Mok Ko, N. Yang, Young Goo Kim
Spindle cell lipoma is a subtype of lipoma first defined by Enzinger and Harvey; it accounts for <1.5% of all lipomatous tumors. We present an unusual case of a huge spindle cell lipoma. A 49-year-old man with diabetes mellitus experienced neck pain during sleep because of a huge occipital and upper posterior neck mass that had slowly grown during 4 years. We performed local excision of the tumor, and pathological findings confirmed the diagnosis of spindle cell lipoma measuring 10×9.5×5 cm. There was no recurrence 1 year after the surgery.
梭形细胞脂肪瘤是由Enzinger和Harvey首先定义的一种脂肪瘤亚型;它占所有脂肪瘤性肿瘤的<1.5%。我们报告一个罕见的巨大梭形细胞脂肪瘤病例。一位49岁男性糖尿病患者在睡眠中出现颈部疼痛,原因是4年来缓慢增长的巨大枕部和颈部后上部肿块。我们对肿瘤进行了局部切除,病理结果证实了梭形细胞脂肪瘤的诊断,尺寸为10×9.5×5 cm。术后1年无复发。
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引用次数: 0
Radiation-induced change after Gamma Knife radiosurgery for cerebral arteriovenous malformations 伽玛刀放射治疗脑动静脉畸形后放射诱导的改变
Pub Date : 2023-06-30 DOI: 10.52662/jksfn.2023.00031
Hak Su Lee, Hae Yu Kim, Sun-il Lee, J. Woo, Sung-Chul Jin, Moo Seong Kim
Objective: Radiation-induced change (RIC) on magnetic resonance imaging after Gamma Knife radiosurgery (GKRS) for cerebral arteriovenous malformations (AVMs) is not rare. We reviewed patients who underwent GKRS for AVMs and analyzed the results and factors associated with RIC.Methods: We reviewed 189 patients who underwent GKRS for AVMs between October 2002 and August 2017. All patients were followed up for at least 3 years. This study included 111 males and 78 females (mean age, 39.63 years; range, 3–79 years). Nineteen patients underwent pre-GKRS embolization. Seventy-six patients had ruptured AVMs and 113 had unruptured AVMs. We analyzed obliteration and RIC occurrence rates. Several demographic and clinical factors were analyzed to determine the influence of AVM obliteration on RIC occurrence.Results: The overall obliteration rate (OR) was 72.49% (137/189) at the final follow-up. The actuarial OR was 55.5% 36 months after GKRS. The overall RIC occurrence rate was 28.04% (53/189), and the actuarial RIC occurrence rate was 26.8% 24 months after GKRS. The OR showed a statistically significant difference according to AVM rupture (p<0.01) and sex (p<0.01). The RIC occurrence rate was significantly associated with AVM rupture (p<0.01), lesion volume (p=0.04), and treatment volume (p=0.03). Other factors showed statistically non-significant relationships.Conclusion: The overall OR after GKRS for AVMs was comparable to the results of other previous reports. RIC is a common postoperative outcome following GKRS for AVMs. In this study, the OR was higher in ruptured AVMs and male patients, whereas RIC occurred more frequently in larger and unruptured AVMs.
目的:伽玛刀放射治疗脑动静脉畸形(AVMs)后磁共振成像的辐射诱导改变(RIC)并不少见。我们回顾了因avm而接受GKRS的患者,并分析了与RIC相关的结果和因素。方法:我们回顾了2002年10月至2017年8月期间接受GKRS治疗AVMs的189例患者。所有患者均随访至少3年。本研究纳入男性111例,女性78例,平均年龄39.63岁;范围3-79年)。19例患者行gkrs前栓塞。76例avm破裂,113例avm未破裂。我们分析了闭塞和RIC的发生率。分析了几种人口统计学和临床因素,以确定AVM闭塞对RIC发生的影响。结果:末次随访时,总闭塞率(OR)为72.49%(137/189)。GKRS后36个月的精算OR为55.5%。GKRS后24个月,总RIC发生率为28.04%(53/189),精算RIC发生率为26.8%。根据AVM破裂的不同,OR差异有统计学意义(p<0.01),性别差异有统计学意义(p<0.01)。RIC发生率与AVM破裂(p<0.01)、病变体积(p=0.04)、治疗体积(p=0.03)相关。其他因素没有统计学上的显著关系。结论:GKRS治疗AVMs后的总体OR与以往报道的结果相当。RIC是avm GKRS术后常见的结果。在本研究中,破裂的动静脉畸形和男性患者的OR更高,而在较大和未破裂的动静脉畸形中,RIC发生的频率更高。
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引用次数: 0
Unexpected cardiac arrest in the neurosurgical ward 神经外科病房意外心脏骤停
Pub Date : 2023-06-30 DOI: 10.52662/jksfn.2023.00017
Jun-Ik Son, M. Ko, Young-Seok Lee, S. Lee, J. Jang, Yong-sook Park
Objective: This study aimed to identify possible predictors of unexpected cardiac arrest (CA) in the neurosurgical ward.Methods: A retrospective review of 24 patients who experienced unexpected CA between December 2012 and March 2022 was conducted. Data on demographics, diagnoses, comorbidities, CA timing, pre-CA vital signs, transfer interval from intensive care unit (ICU) to ward, cardiac rhythm, neurological outcomes, and probable causes were collected. We excluded patients who died in the ICU and those with a do-not-resuscitate order.Results: The average age was 70.3 years. Vascular diseases and head traumas were common diagnoses. About 70.8% of arrests occurred during on-call time and 62.5% took place on weekends. The mean interval between ICU transfer and CA was 13.8±29.7 days, with 54.2% occurring within 4 days and 83.3% within 14 days. Pulseless electrical activity was the most frequent initial cardiac rhythm when CA occurred. Respiratory issues were the leading cause of CA (54.2%), and 91.7% of patients had poor neurological outcomes. Within 48 hours before CA, the average value of the lowest arterial oxygen saturation significantly deteriorated from 95.8±2.9% to 90.1±11.4%.Conclusion: Unexpected CA often occurred on weekends and during night duty. Half of the cases took place within 4 days and over 80% within 2 weeks of transferring from the ICU to the ward, with respiratory problems being the main cause. Greater attention should be given to patients’ breathing patterns during night shifts and weekends, especially within the first 2 weeks after patients leave the ICU.
目的:本研究旨在确定神经外科病房意外心脏骤停(CA)的可能预测因素。方法:回顾性分析2012年12月至2022年3月期间发生意外CA的24例患者。收集了人口统计学、诊断、合并症、CA时间、CA前生命体征、从重症监护病房(ICU)到病房的转移间隔、心律、神经预后和可能原因的数据。我们排除了在ICU死亡的患者和那些有不复苏命令的患者。结果:平均年龄70.3岁。血管疾病和头部创伤是常见的诊断。约70.8%的逮捕发生在当值时间,62.5%发生在周末。ICU转移至CA的平均间隔时间为13.8±29.7天,其中54.2%发生在4天内,83.3%发生在14天内。无脉性电活动是CA发生时最常见的初始心律。呼吸问题是CA的主要原因(54.2%),91.7%的患者神经系统预后较差。CA前48 h内最低动脉血氧饱和度平均值由95.8±2.9%下降至90.1±11.4%。结论:意外CA常发生在周末和夜班。一半的病例发生在从ICU转到病房的4天内,超过80%的病例发生在2周内,呼吸问题是主要原因。在夜班和周末期间,尤其在患者离开ICU后的头两周内,应更加关注患者的呼吸模式。
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引用次数: 0
Risk factors associated with slit ventricle syndrome after ventriculoperitoneal shunt surgery 脑室腹腔分流手术后狭缝脑室综合征的相关危险因素
Pub Date : 2023-06-30 DOI: 10.52662/jksfn.2023.00024
Joseph Hwang, Jae Meen Lee
Objective: Slit ventricle syndrome (SVS) is defined as a slit-like appearance of the lateral ventricles with associated symptoms such as headache, vomiting, or drowsiness. The study investigated the risk factors associated with the incidence of SVS following ventriculoperitoneal shunt surgery.Methods: We retrospectively reviewed the medical records of patients who underwent ventriculoperitoneal shunt surgery from January 2011 to 2019 at a single institution. SVS was diagnosed by a slit-like appearance of the lateral ventricles and a low Evan’s ratio (<0.25) on follow-up radiologic images. Results: SVS was diagnosed in 53 (18.2%) of 292 patients who underwent ventriculoperitoneal shunt surgery. The mean age of patients with SVS (48.3 years; range, 4–85 years) was significantly lower than the mean age of those without SVS (58.4 years; range, 0.5–85 years) (p=0.024). Male patients showed a slightly higher incidence of SVS, but the result was not statistically significant. Patients who had hydrocephalus with vascular causes (e.g. subarachnoid hemorrhage and intracranial hematoma) showed a significantly lower incidence of SVS than those with non-vascular causes (p=0.002).Conclusion: The incidence of SVS was higher in younger patients and in those with a non-vascular cause of hydrocephalus.
目的:狭缝脑室综合征(SVS)被定义为侧脑室狭缝样外观,伴有头痛、呕吐或嗜睡等相关症状。该研究调查了脑室-腹膜分流术后SVS发生的相关危险因素。方法:我们回顾性分析了2011年1月至2019年在单一机构接受脑室-腹膜分流术的患者的病历。通过侧脑室的裂隙样外观和随访放射图像的低Evan’s比率(<0.25)来诊断SVS。结果:292例行脑室-腹膜分流术的患者中有53例(18.2%)被诊断为SVS。SVS患者的平均年龄(48.3岁;范围(4 ~ 85岁)显著低于无SVS组的平均年龄(58.4岁;范围,0.5-85年)(p=0.024)。男性患者SVS发生率略高,但结果无统计学意义。血管性脑积水患者(如蛛网膜下腔出血、颅内血肿)的SVS发生率明显低于非血管性脑积水患者(p=0.002)。结论:年轻患者和非血管性脑积水患者的SVS发生率较高。
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引用次数: 0
Medical insurance coverage of radiosurgery for glossopharyngeal neuralgia in Korea 韩国放射外科治疗舌咽神经痛的医疗保险范围
Pub Date : 2023-03-13 DOI: 10.52662/jksfn.2022.00213
Y. Ahn
{"title":"Medical insurance coverage of radiosurgery for glossopharyngeal neuralgia in Korea","authors":"Y. Ahn","doi":"10.52662/jksfn.2022.00213","DOIUrl":"https://doi.org/10.52662/jksfn.2022.00213","url":null,"abstract":"","PeriodicalId":193825,"journal":{"name":"Journal of the Korean Society of Stereotactic and Functional Neurosurgery","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116909953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of the Korean Society of Stereotactic and Functional Neurosurgery
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