Pub Date : 2023-09-06DOI: 10.15406/ogij.2023.14.00709
Elena García García, S De Miguel Manso, M Ibañez Nieto, M Cuaresma González, JA Gobernado Tejedor, M Pérez Febles, M López País
Objectives: The recurrence of SUI after surgery with TO represents a frequent complication whose etiology has not been clarified. Our study aims to establish the SUI recurrence rate in patients operated on at our center as well as to analyze the possible factors associated with the risk of recurrence, during a 9-year follow-up. Methods: Prospective descriptive observational study, conducted at the Hospital Clínico Universitario de Valladolid, between January 2012 and March 2021, including 133 patients. Results: Our study describes a recurrence rate of SUI after TO of 12%, with a statistically significant relationship (p 0.009) between the year of postoperative follow-up and the risk of recurrence. The risk of recurrence at 9 years was related to advanced age, macrosomic delivery, and multiparity. Conclusions: We must identify those patients whose risk factors allow us to anticipate a torpid evolution, considering therapeutic alternatives, for example, in young women or who have not completed their reproductive desire.
{"title":"Recurrence of stress urinary incontinence in women treated with transobturator suburethral mesh: 9-year follow-up","authors":"Elena García García, S De Miguel Manso, M Ibañez Nieto, M Cuaresma González, JA Gobernado Tejedor, M Pérez Febles, M López País","doi":"10.15406/ogij.2023.14.00709","DOIUrl":"https://doi.org/10.15406/ogij.2023.14.00709","url":null,"abstract":"Objectives: The recurrence of SUI after surgery with TO represents a frequent complication whose etiology has not been clarified. Our study aims to establish the SUI recurrence rate in patients operated on at our center as well as to analyze the possible factors associated with the risk of recurrence, during a 9-year follow-up. Methods: Prospective descriptive observational study, conducted at the Hospital Clínico Universitario de Valladolid, between January 2012 and March 2021, including 133 patients. Results: Our study describes a recurrence rate of SUI after TO of 12%, with a statistically significant relationship (p 0.009) between the year of postoperative follow-up and the risk of recurrence. The risk of recurrence at 9 years was related to advanced age, macrosomic delivery, and multiparity. Conclusions: We must identify those patients whose risk factors allow us to anticipate a torpid evolution, considering therapeutic alternatives, for example, in young women or who have not completed their reproductive desire.","PeriodicalId":19389,"journal":{"name":"Obstetrics & Gynecology International Journal","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135204514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-16DOI: 10.15406/ogij.2023.14.00684
Saadi AlJadir
Fermentation of foods had been dated to early human life on the planet far more before civilization. The transition from hunting and gathering to the agricultural lifestyle might have triggered task of food fermentations, nowadays this task is carried on industrial level. Many parts of the human body; the skin, oral cavity, gut, and vaginal canal are populated by huge numbers of microbes. At birth, human gut is a sterile environment, however it will start to be colonized instantly after birth. Factors such as diet (formula or breast feeding) and type of delivery (either vaginal birth or abdominal) can both impact the colonization patterns. The pioneer microbes inhabiting the gut make permanent adaptations and thus determining the metabolic, physiological, behavioral, and immune development which will encourage vulnerability to diseases. Because Age and lifestyle are associated with alteration in microflora, therefore are of some causes of diseases. Latest research has shown that microbiota composition is remarkably different in diseases such as obesity and periodontal diseases with healthy individuals usually showing diverse, distinct, and temporary stable microbiota communities at these sites in comparison with individuals manifesting disease.
{"title":"Probiotics and women health: clinical perspective","authors":"Saadi AlJadir","doi":"10.15406/ogij.2023.14.00684","DOIUrl":"https://doi.org/10.15406/ogij.2023.14.00684","url":null,"abstract":"Fermentation of foods had been dated to early human life on the planet far more before civilization. The transition from hunting and gathering to the agricultural lifestyle might have triggered task of food fermentations, nowadays this task is carried on industrial level. Many parts of the human body; the skin, oral cavity, gut, and vaginal canal are populated by huge numbers of microbes. At birth, human gut is a sterile environment, however it will start to be colonized instantly after birth. Factors such as diet (formula or breast feeding) and type of delivery (either vaginal birth or abdominal) can both impact the colonization patterns. The pioneer microbes inhabiting the gut make permanent adaptations and thus determining the metabolic, physiological, behavioral, and immune development which will encourage vulnerability to diseases. Because Age and lifestyle are associated with alteration in microflora, therefore are of some causes of diseases. Latest research has shown that microbiota composition is remarkably different in diseases such as obesity and periodontal diseases with healthy individuals usually showing diverse, distinct, and temporary stable microbiota communities at these sites in comparison with individuals manifesting disease.","PeriodicalId":19389,"journal":{"name":"Obstetrics & Gynecology International Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135695201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-10DOI: 10.15406/ogij.2022.13.00618
A. G. Mudau
Background: Breastmilk only is enough for milestone of a child because it contains all necessary nutrients. Because of its benefits World Health Organization recommends that lactating mothers must give their infants only breastmilk for six months and continue up to two years with appropriate complementary food. Despite its benefits breastfeeding is not well practiced in developing countries, South Africa included. Objective: This study aimed to investigate enabling, reinforcing and predisposing factors influencing exclusive breastfeeding interruption among lactating mothers in Limpopo Province. Methods and materials: This study was cross sectional which employed quantitative measures. Data was collected from 399 lactating mothers during immunization in the selected birthing facilities of Limpopo Province and analysed using SPSS version 26. Results: The findings indicate that breastfeeding mothers were likely to stop breastfeeding completely when their babies were three months old. The findings were that the majority 72.9% of the mothers practised mixed feeding and the minority, only 27.1% practised EBF. It was also found that 38.5% mothers gave water to the infants, 30.2% were given soft porridge and 26.1% formula. Conclusion: The study revealed that the factors that affect exclusive breastfeeding include: influence from the Parents/in-laws Insufficient breastmilk, religious and cultural beliefs, illness of the mothers and young mothers and going back to work/school.
{"title":"Enabling, predisposing, and reinforcing factors influencing implementation of exclusive breastfeeding among lactating mothers in Limpopo Province, South Africa","authors":"A. G. Mudau","doi":"10.15406/ogij.2022.13.00618","DOIUrl":"https://doi.org/10.15406/ogij.2022.13.00618","url":null,"abstract":"Background: Breastmilk only is enough for milestone of a child because it contains all necessary nutrients. Because of its benefits World Health Organization recommends that lactating mothers must give their infants only breastmilk for six months and continue up to two years with appropriate complementary food. Despite its benefits breastfeeding is not well practiced in developing countries, South Africa included. Objective: This study aimed to investigate enabling, reinforcing and predisposing factors influencing exclusive breastfeeding interruption among lactating mothers in Limpopo Province. Methods and materials: This study was cross sectional which employed quantitative measures. Data was collected from 399 lactating mothers during immunization in the selected birthing facilities of Limpopo Province and analysed using SPSS version 26. Results: The findings indicate that breastfeeding mothers were likely to stop breastfeeding completely when their babies were three months old. The findings were that the majority 72.9% of the mothers practised mixed feeding and the minority, only 27.1% practised EBF. It was also found that 38.5% mothers gave water to the infants, 30.2% were given soft porridge and 26.1% formula. Conclusion: The study revealed that the factors that affect exclusive breastfeeding include: influence from the Parents/in-laws Insufficient breastmilk, religious and cultural beliefs, illness of the mothers and young mothers and going back to work/school.","PeriodicalId":19389,"journal":{"name":"Obstetrics & Gynecology International Journal","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88496543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-05DOI: 10.15406/ogij.2022.13.00617
Vargas Hernández Víctor Manuel, Luján Irastorza Jesús Estuardo, D. Carlos, H. Roberto, Ávila Pérez Felipe de Jesús, Á. Daniela, K. Alejandro, Guerrero Vargas José Juan, Valdez-Chávez Teresita de Jesús, Silva-Meléndez Jorge, Yáñez-González Marco Antonio, García-Cruz Valeria, Loof-Esquivel Mónica, Beltrán-Tapia José Luis, Peñalva-Rosales Samuel Octavio, Vargas Hernández Víctor Manuel
Background: Labor is a physiological process during which the fetus, the membranes, the umbilical cord and the placenta are expelled from the uterus and water delivery has become popular, although its prevalence is unknown, it is supported by healthy women with full-term pregnancies, without complications; although there is insufficient evidence to support or discourage it. Objective: To identify obstetric and neonatal outcomes and complications in women who delivered in water and to compare them with traditional deliveries. Material and methods: It is a retrospective, observational and cross-sectional study, where 2486 women were included from a database of 4223 women assisted from 2004 to 2020 in private hospitals; Of the 2486 patients included, 1025 had a water delivery and 1461 had a conventional delivery, discarding 1737 women who underwent caesarean section from the study. The information obtained from the patients, their data obtained for this study were kept in the anonymity of the patients, where they were analyzed: non-parametric data reported in percentages using Chi square; Parametric, perinatal and neonatal data are reported as mean plus standard deviation (±SD) and analyzed using Student's T, using the SPSS version 25 statistical package. Results: A total of 2486 women were included in this study, the birth in 1025 was water delivery (24%) and 1461 was conventional delivery (35%), 1737 caesarean section (41%) were excluded from the study, no difference was observed maternal age; unlike weight, height, body mass index; they were higher in women with water birth compared to conventional. No difference was demonstrated between nulliparous (45.99%) and multiparous (53.86%) when comparing both birth in water and conventional; only increase in previous caesarean sections (9.36 vs 6.5%, p=0.008) and decrease in previous abortions (16.19 vs 20.94%, p=0.002) in water delivery with the conventional one; complications were not different: administration of oxytocin (3.2 vs 3.1) or postpartum hemorrhage (0.29 vs 0.13) in both deliveries; no differences in first degree perineal tears (21.4 vs 18.5%). Conclusion: Water birth reduces stress, pain sensation, second and third degree perineal lacerations and contributes to better newborn outcomes; the selection and inclusion of patients with low-risk pregnancies allows better perinatal results than conventional delivery; but, further studies are required to use it routinely.
背景:分娩是胎儿、胎膜、脐带和胎盘从子宫中排出的生理过程，水分娩已成为一种流行方式，虽然患病率不详，但在足月妊娠的健康妇女中得到支持，无并发症;尽管没有足够的证据支持或反对它。目的:确定水中分娩妇女的产科和新生儿结局及并发症，并将其与传统分娩进行比较。材料和方法:这是一项回顾性、观察性和横断面研究，从2004年至2020年在私立医院接受援助的4223名妇女的数据库中纳入2486名妇女;在纳入的2486名患者中，1025名患者进行了水中分娩，1461名患者进行了常规分娩，从研究中剔除了1737名接受剖腹产的女性。从患者那里获得的信息，他们为这项研究获得的数据都是匿名的，在那里他们被分析:非参数数据以百分比报告，使用卡方;参数、围产期和新生儿数据以平均值加标准差(±SD)报告，并使用SPSS 25版统计软件包使用Student's T进行分析。结果:本研究共纳入2486例妇女，其中水中分娩1025例(24%)，常规分娩1461例(35%)，剖宫产1737例(41%)被排除在研究之外，产妇年龄无差异;不像体重，身高，身体质量指数;与传统分娩方式相比，在水中分娩的妇女中这一比例更高。水中分娩与常规分娩相比，无产仔(45.99%)与多产仔(53.86%)差异无统计学意义;与常规分娩相比，水分娩仅增加了剖宫产史(9.36% vs 6.5%， p=0.008)，减少了流产史(16.19% vs 20.94%， p=0.002);并发症无差异:两次分娩均使用催产素(3.2 vs 3.1)或产后出血(0.29 vs 0.13);会阴一级撕裂无差异(21.4% vs 18.5%)。结论:水中分娩可减轻压力、疼痛感、二度和三度会阴撕裂伤，新生儿预后较好;选择和纳入低风险妊娠患者比传统分娩可获得更好的围产期结果;但是，需要进一步的研究来常规使用它。
{"title":"Delivery in water, experiences in a population of Mexican women in Mexico City","authors":"Vargas Hernández Víctor Manuel, Luján Irastorza Jesús Estuardo, D. Carlos, H. Roberto, Ávila Pérez Felipe de Jesús, Á. Daniela, K. Alejandro, Guerrero Vargas José Juan, Valdez-Chávez Teresita de Jesús, Silva-Meléndez Jorge, Yáñez-González Marco Antonio, García-Cruz Valeria, Loof-Esquivel Mónica, Beltrán-Tapia José Luis, Peñalva-Rosales Samuel Octavio, Vargas Hernández Víctor Manuel","doi":"10.15406/ogij.2022.13.00617","DOIUrl":"https://doi.org/10.15406/ogij.2022.13.00617","url":null,"abstract":"Background: Labor is a physiological process during which the fetus, the membranes, the umbilical cord and the placenta are expelled from the uterus and water delivery has become popular, although its prevalence is unknown, it is supported by healthy women with full-term pregnancies, without complications; although there is insufficient evidence to support or discourage it. Objective: To identify obstetric and neonatal outcomes and complications in women who delivered in water and to compare them with traditional deliveries. Material and methods: It is a retrospective, observational and cross-sectional study, where 2486 women were included from a database of 4223 women assisted from 2004 to 2020 in private hospitals; Of the 2486 patients included, 1025 had a water delivery and 1461 had a conventional delivery, discarding 1737 women who underwent caesarean section from the study. The information obtained from the patients, their data obtained for this study were kept in the anonymity of the patients, where they were analyzed: non-parametric data reported in percentages using Chi square; Parametric, perinatal and neonatal data are reported as mean plus standard deviation (±SD) and analyzed using Student's T, using the SPSS version 25 statistical package. Results: A total of 2486 women were included in this study, the birth in 1025 was water delivery (24%) and 1461 was conventional delivery (35%), 1737 caesarean section (41%) were excluded from the study, no difference was observed maternal age; unlike weight, height, body mass index; they were higher in women with water birth compared to conventional. No difference was demonstrated between nulliparous (45.99%) and multiparous (53.86%) when comparing both birth in water and conventional; only increase in previous caesarean sections (9.36 vs 6.5%, p=0.008) and decrease in previous abortions (16.19 vs 20.94%, p=0.002) in water delivery with the conventional one; complications were not different: administration of oxytocin (3.2 vs 3.1) or postpartum hemorrhage (0.29 vs 0.13) in both deliveries; no differences in first degree perineal tears (21.4 vs 18.5%). Conclusion: Water birth reduces stress, pain sensation, second and third degree perineal lacerations and contributes to better newborn outcomes; the selection and inclusion of patients with low-risk pregnancies allows better perinatal results than conventional delivery; but, further studies are required to use it routinely.","PeriodicalId":19389,"journal":{"name":"Obstetrics & Gynecology International Journal","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81762286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-20DOI: 10.15406/ogij.2021.12.00613
Bin Zhao, Renxiong Xie, Xia Jiang
Breast cancer is one of the most lethal cancers, estrogen receptor α Subtype (ERα) is an important target. The compounds that able to fight ERα active may be candidates for treatment of breast cancer. The drug discovery process is a very large and complex process that often requires one selected from a large number of compounds. This paper considers the independence, coupling, and relevance of bioactivity descriptors, selects the 15 most potentially valuable bioactivity descriptors from 729 bioactivity descriptors. An optimized back propagation neural network is used for ERα, The pharmacokinetics and safety of 15 selected bioactivity descriptors were verified by gradient lifting algorithm. The results showed that these 15 biological activity descriptors could not only fit well with the nonlinear relationship of ERα activity can also accurately predict its pharmacokinetic characteristics and safety, with an average accuracy of 89.92~94.80%. Therefore, these biological activity descriptors have great medical research value.
{"title":"Anti-breast cancer drug screening based on Neural Networks and QSAR model","authors":"Bin Zhao, Renxiong Xie, Xia Jiang","doi":"10.15406/ogij.2021.12.00613","DOIUrl":"https://doi.org/10.15406/ogij.2021.12.00613","url":null,"abstract":"Breast cancer is one of the most lethal cancers, estrogen receptor α Subtype (ERα) is an important target. The compounds that able to fight ERα active may be candidates for treatment of breast cancer. The drug discovery process is a very large and complex process that often requires one selected from a large number of compounds. This paper considers the independence, coupling, and relevance of bioactivity descriptors, selects the 15 most potentially valuable bioactivity descriptors from 729 bioactivity descriptors. An optimized back propagation neural network is used for ERα, The pharmacokinetics and safety of 15 selected bioactivity descriptors were verified by gradient lifting algorithm. The results showed that these 15 biological activity descriptors could not only fit well with the nonlinear relationship of ERα activity can also accurately predict its pharmacokinetic characteristics and safety, with an average accuracy of 89.92~94.80%. Therefore, these biological activity descriptors have great medical research value.","PeriodicalId":19389,"journal":{"name":"Obstetrics & Gynecology International Journal","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88043265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-20DOI: 10.15406/ogij.2021.12.00616
V. M. Vargas Hernández, Machuca-Hernandez Violeta Fabiola, Víctor Manuel Vargas-Aguilar, Agustín I Rodríguez Blaz, José Raúl Rodríguez Rodríguez
Background: Ovarian germ cell tumors are derived from the primordial germ cells of the ovary, they can be benign or malignant. Non-gestational ovarian choriocarcinoma is extremely rare and aggressive that are of gestational or non-gestational origin, its prevalence is less than 0.6% of all ovarian germ cell tumors. Due to the rarity of the tumor, there is a lack of information on the clinical-pathological characteristics, diagnosis and treatment. Objective: present a case of non-gestational ovarian choriocarcioma and review of the literature Clinical case: We present the case of a 20-year-old woman who presented with an acute abdomen, due to abdominal pain and distention, with scant vaginal bleeding and pain on cervical mobilization; An ultrasound was performed with a right annex with a lesion measuring 114 x83x79mm and a total volume of 394cc, heterogeneous with linear images inside punctiform and human chorionic beta-gonadotropin levels, elevated 112.337 mUI/mL, the patient underwent an exploratory laparotomy with the finding of an ovarian tumor; performing salpingo-oophorectomy and the histopathological report of the definitive surgical specimen and immunohistochemical study, the diagnosis of non-gestational ovarian choriocarcinoma was made. Conclusion: Non-gestational choriocarcinoma is an extremely rare malignant neoplasm that can present clinically in different ways, even as an acute abdomen, which requires differential diagnoses and management is the combination of surgery and adjuvant chemotherapy.
{"title":"Non-gestational primary choriocarcinoma of the ovary. Presentation of a clinical case","authors":"V. M. Vargas Hernández, Machuca-Hernandez Violeta Fabiola, Víctor Manuel Vargas-Aguilar, Agustín I Rodríguez Blaz, José Raúl Rodríguez Rodríguez","doi":"10.15406/ogij.2021.12.00616","DOIUrl":"https://doi.org/10.15406/ogij.2021.12.00616","url":null,"abstract":"Background: Ovarian germ cell tumors are derived from the primordial germ cells of the ovary, they can be benign or malignant. Non-gestational ovarian choriocarcinoma is extremely rare and aggressive that are of gestational or non-gestational origin, its prevalence is less than 0.6% of all ovarian germ cell tumors. Due to the rarity of the tumor, there is a lack of information on the clinical-pathological characteristics, diagnosis and treatment. Objective: present a case of non-gestational ovarian choriocarcioma and review of the literature Clinical case: We present the case of a 20-year-old woman who presented with an acute abdomen, due to abdominal pain and distention, with scant vaginal bleeding and pain on cervical mobilization; An ultrasound was performed with a right annex with a lesion measuring 114 x83x79mm and a total volume of 394cc, heterogeneous with linear images inside punctiform and human chorionic beta-gonadotropin levels, elevated 112.337 mUI/mL, the patient underwent an exploratory laparotomy with the finding of an ovarian tumor; performing salpingo-oophorectomy and the histopathological report of the definitive surgical specimen and immunohistochemical study, the diagnosis of non-gestational ovarian choriocarcinoma was made. Conclusion: Non-gestational choriocarcinoma is an extremely rare malignant neoplasm that can present clinically in different ways, even as an acute abdomen, which requires differential diagnoses and management is the combination of surgery and adjuvant chemotherapy.","PeriodicalId":19389,"journal":{"name":"Obstetrics & Gynecology International Journal","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84893462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-17DOI: 10.15406/ogij.2021.12.00612
Alfredo Camargo MD PhD, Federico Bianchi MD, Fernando Dip MD, Diego Habich MD, Tomas Ramilo MD, Tomas Garcia Balcarce MD, Codoni Maria Jose MD, Roberto Castaño MD PhD, Raul Rosenthal MD, FACS, FASMBS, Di Sanzo Natalia
Background: Near-infrared fluorescence-based sentinel lymph node (SLN) mapping technique with indocyanine green (ICG) has been found a useful surgical modality for sentinel node detection and disease staging in endometrial cancer (EC) worldwide. Objective: We aimed to introduce the SNL mapping technology using ICG and Near Infrared (NIR) fluorescence in Argentina. We aimed to assess the overall and bilateral detection rate of ICG based SNL mapping along with verifying its feasibility and effectiveness in surgical staging. We also aimed to discover the perceptions of surgeons regarding the use of ICG as a tracer and NIR as light-medium in SNL mapping. Method: ICG SLNs identification was evaluated retrospectively. This study was performed at the Hospital Aleman de Buenos Aires in September, 2017The detection rates were calculated along with the analysis of the number of SNL observed and operative time, and time taken by overall surgery. Subsequently, the surgeons were interviewed to ascertain their opinion of using ICG SNL mapping in endometrial cancer staging. Results: Four patients with endometrial cancer were included for analysis. The overall and bilateral detection rates have been 100% and 75%, respectively. While, under white light, no SLNs were identified. The average operative time of nodes resection was estimated 2.15 minutes. The fluorescence has been used for 2.2 minutes and overall time taken by surgery was estimated 71.5 minutes. The estimated blood loss (EBL) has been lower than 50 ml. The responses of surgeons’ from the interview have been 100% positive. The cost of the procedure based on the amount of dye used was 25 dollars per patient. Conclusion: Laparoscopic ICG SLN resulted to be feasible, practical and no expensive surgical modality for uterine cancer triage.
背景:近红外荧光前哨淋巴结(SLN)定位技术与吲哚菁绿(ICG)已被发现在子宫内膜癌(EC)的前哨淋巴结检测和疾病分期的一种有用的手术方式。目的:介绍利用ICG和近红外(NIR)荧光技术在阿根廷的SNL定位技术。我们的目的是评估基于ICG的SNL定位的整体和双侧检出率，并验证其在手术分期中的可行性和有效性。我们还旨在发现外科医生对在SNL制图中使用ICG作为示踪剂和近红外作为光介质的看法。方法:回顾性评价ICG sln的鉴别。本研究于2017年9月在Aleman de Buenos Aires医院进行，计算检出率并分析观察到的SNL次数、手术时间和总手术时间。随后，对外科医生进行了访谈，以确定他们对使用ICG SNL作图进行子宫内膜癌分期的看法。结果:纳入4例子宫内膜癌患者进行分析。总检出率为100%，双侧检出率为75%。而在白光下，没有识别出sln。淋巴结切除平均手术时间估计为2.15分钟。荧光使用了2.2分钟，手术总时间估计为71.5分钟。估计失血量(EBL)已低于50毫升。从访谈中外科医生的反应是100%肯定的。根据使用的染料数量，该手术的费用为每位患者25美元。结论:腹腔镜ICG SLN是一种可行、实用、费用低廉的子宫癌分诊手术方式。
{"title":"Fluorescent sentinel lymph node mapping with icg in endometrial cancer. An initial experience in Argentina","authors":"Alfredo Camargo MD PhD, Federico Bianchi MD, Fernando Dip MD, Diego Habich MD, Tomas Ramilo MD, Tomas Garcia Balcarce MD, Codoni Maria Jose MD, Roberto Castaño MD PhD, Raul Rosenthal MD, FACS, FASMBS, Di Sanzo Natalia","doi":"10.15406/ogij.2021.12.00612","DOIUrl":"https://doi.org/10.15406/ogij.2021.12.00612","url":null,"abstract":"Background: Near-infrared fluorescence-based sentinel lymph node (SLN) mapping technique with indocyanine green (ICG) has been found a useful surgical modality for sentinel node detection and disease staging in endometrial cancer (EC) worldwide. Objective: We aimed to introduce the SNL mapping technology using ICG and Near Infrared (NIR) fluorescence in Argentina. We aimed to assess the overall and bilateral detection rate of ICG based SNL mapping along with verifying its feasibility and effectiveness in surgical staging. We also aimed to discover the perceptions of surgeons regarding the use of ICG as a tracer and NIR as light-medium in SNL mapping. Method: ICG SLNs identification was evaluated retrospectively. This study was performed at the Hospital Aleman de Buenos Aires in September, 2017The detection rates were calculated along with the analysis of the number of SNL observed and operative time, and time taken by overall surgery. Subsequently, the surgeons were interviewed to ascertain their opinion of using ICG SNL mapping in endometrial cancer staging. Results: Four patients with endometrial cancer were included for analysis. The overall and bilateral detection rates have been 100% and 75%, respectively. While, under white light, no SLNs were identified. The average operative time of nodes resection was estimated 2.15 minutes. The fluorescence has been used for 2.2 minutes and overall time taken by surgery was estimated 71.5 minutes. The estimated blood loss (EBL) has been lower than 50 ml. The responses of surgeons’ from the interview have been 100% positive. The cost of the procedure based on the amount of dye used was 25 dollars per patient. Conclusion: Laparoscopic ICG SLN resulted to be feasible, practical and no expensive surgical modality for uterine cancer triage.","PeriodicalId":19389,"journal":{"name":"Obstetrics & Gynecology International Journal","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75833086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-08DOI: 10.15406/ogij.2021.12.00611
Ana Leslie Tijero Espinoza, Dante Junior Segura Pinedo, San Enrique
Tetralogy of Fallot is the most common cyanotic congenital heart disease. Hemodynamic changes can cause serious and fatal multi-organ complications, the choice of anesthesia is very difficult.Combined spinal epidural techniques have become an alternative to traditional neuraxial interventions; the advantages of spinal or subarachnoid block are fused with the flexibility of the epidural technique; they offer a fast, effective and minimally toxic spinal block, improve inadequate block, and prolong the duration of anesthesia with epidural supplements.The purpose of this article is to report the case of a pregnant woman with a diagnosis of uncorrected Tetralogy of Fallot and the anesthetic technique of effective establishment without producing harmful hemodynamic changes for the mother-child binomial.
{"title":"Anesthesia for cesarean in pregnant with uncorrected failot tetralogy","authors":"Ana Leslie Tijero Espinoza, Dante Junior Segura Pinedo, San Enrique","doi":"10.15406/ogij.2021.12.00611","DOIUrl":"https://doi.org/10.15406/ogij.2021.12.00611","url":null,"abstract":"Tetralogy of Fallot is the most common cyanotic congenital heart disease. Hemodynamic changes can cause serious and fatal multi-organ complications, the choice of anesthesia is very difficult.Combined spinal epidural techniques have become an alternative to traditional neuraxial interventions; the advantages of spinal or subarachnoid block are fused with the flexibility of the epidural technique; they offer a fast, effective and minimally toxic spinal block, improve inadequate block, and prolong the duration of anesthesia with epidural supplements.The purpose of this article is to report the case of a pregnant woman with a diagnosis of uncorrected Tetralogy of Fallot and the anesthetic technique of effective establishment without producing harmful hemodynamic changes for the mother-child binomial.","PeriodicalId":19389,"journal":{"name":"Obstetrics & Gynecology International Journal","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74433929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-02DOI: 10.15406/ogij.2021.12.00610
G. Almind, A. Abraham-Zadeh, E. Faerch, F. Lindenberg, S. Smidt‐Jensen, S. Lindenberg
Aim of study: Over the last decade, laboratory procedures in in vitro fertilisation (IVF) have improved. Hyperstimulated ovaries cause an overload of surplus embryos. The present study was designed to evaluate the efficiency of two different modified IVF cycle protocols trying to reduce the load of medication used for IVF: simple IVF (S-IVF), Tamoxifen 40 mg daily from day 2 in the cycle to ovulation induction) and mild IVF (M-IVF), Tamoxifen 40 mg daily and every secondary 150 IU Gonal F until ovulation induction. The study aims to evaluate their efficiency compared with our conventional IVF (C-IVF) using a short antagonist protocol. Methods: A retrospective cohort study including all patients admitted to IVF for unexplained infertility, tubal factor, and male factor. In all stimulated cycles patients aimed at having fresh embryos transferred and surplus good embryos cryopreserved. All patients were recruited in the same period and allocated to the different treatments on their own request. The study was conducted between June 2019 and February 2021. Results: In total the study included 976 IVF cycles. 651 cycles from C-IVF, 145 cycles from S-IVF and 180 cycles from M-IVF. Mean age in the groups were comparable. Mean number of eggs retrieved was 6.1 (C-IVF), 1.2 (S-IVF) and 3.0 (M-IVF). Pregnancy rate per fresh transfer was found to be 29% for C-IVF, 26% in the S-IVF group and for the M-IVF 20%. Conclusion: Modified IVF stimulation protocols may be an important step towards a simpler assisted reproductive technology (ART) approach. More tolerable for women, easier and cheaper for patients and society they maintain acceptable clinical pregnancy rates. Large prospective studies need to be performed in the future.
{"title":"Two modified natural in vitro fertilisation (IVF) protocols compared to conventional IVF treatment: Retrospective data from one Danish Fertility Centre","authors":"G. Almind, A. Abraham-Zadeh, E. Faerch, F. Lindenberg, S. Smidt‐Jensen, S. Lindenberg","doi":"10.15406/ogij.2021.12.00610","DOIUrl":"https://doi.org/10.15406/ogij.2021.12.00610","url":null,"abstract":"Aim of study: Over the last decade, laboratory procedures in in vitro fertilisation (IVF) have improved. Hyperstimulated ovaries cause an overload of surplus embryos. The present study was designed to evaluate the efficiency of two different modified IVF cycle protocols trying to reduce the load of medication used for IVF: simple IVF (S-IVF), Tamoxifen 40 mg daily from day 2 in the cycle to ovulation induction) and mild IVF (M-IVF), Tamoxifen 40 mg daily and every secondary 150 IU Gonal F until ovulation induction. The study aims to evaluate their efficiency compared with our conventional IVF (C-IVF) using a short antagonist protocol. Methods: A retrospective cohort study including all patients admitted to IVF for unexplained infertility, tubal factor, and male factor. In all stimulated cycles patients aimed at having fresh embryos transferred and surplus good embryos cryopreserved. All patients were recruited in the same period and allocated to the different treatments on their own request. The study was conducted between June 2019 and February 2021. Results: In total the study included 976 IVF cycles. 651 cycles from C-IVF, 145 cycles from S-IVF and 180 cycles from M-IVF. Mean age in the groups were comparable. Mean number of eggs retrieved was 6.1 (C-IVF), 1.2 (S-IVF) and 3.0 (M-IVF). Pregnancy rate per fresh transfer was found to be 29% for C-IVF, 26% in the S-IVF group and for the M-IVF 20%. Conclusion: Modified IVF stimulation protocols may be an important step towards a simpler assisted reproductive technology (ART) approach. More tolerable for women, easier and cheaper for patients and society they maintain acceptable clinical pregnancy rates. Large prospective studies need to be performed in the future.","PeriodicalId":19389,"journal":{"name":"Obstetrics & Gynecology International Journal","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89596330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-25DOI: 10.15406/ogij.2021.12.00608
Nesreen Abd El Fattah Abd Allah Shehata, H. Ali, Rabab Ashour, Momen Z El nadeim, N. Shehata, Eman M. Khalil
Objective: To detect missed uterine abnormalities on primary work up in unexplained infertile women. Study design: An observational study was performed in the outpatient infertility clinic of Beni-Suef University Hospitals. It included 100 women with unexplained infertility. Diagnostic office hysteroscopy was done for all participants. Women were grouped according to the infertility type and compared as regards uterine abnormalities detected. Results: Uterine abnormalities were detected by hysteroscopy in 29% of women. No significant difference was found regarding the hysteroscopic findings between primary and secondary infertility groups. However, uterine polyp cases were detected more in women with primary infertility (55.5% /18). A significant difference in intrauterine adhesions between both groups being detected only in secondary infertility group (p value =0.006). Conclusion: Outpatient preliminary and routine diagnostic office hysteroscopy may be a beneficial part of a primary and secondary infertility workup.
{"title":"Hysteroscopic evaluation of uterine cavity in women with unexplained infertility","authors":"Nesreen Abd El Fattah Abd Allah Shehata, H. Ali, Rabab Ashour, Momen Z El nadeim, N. Shehata, Eman M. Khalil","doi":"10.15406/ogij.2021.12.00608","DOIUrl":"https://doi.org/10.15406/ogij.2021.12.00608","url":null,"abstract":"Objective: To detect missed uterine abnormalities on primary work up in unexplained infertile women. Study design: An observational study was performed in the outpatient infertility clinic of Beni-Suef University Hospitals. It included 100 women with unexplained infertility. Diagnostic office hysteroscopy was done for all participants. Women were grouped according to the infertility type and compared as regards uterine abnormalities detected. Results: Uterine abnormalities were detected by hysteroscopy in 29% of women. No significant difference was found regarding the hysteroscopic findings between primary and secondary infertility groups. However, uterine polyp cases were detected more in women with primary infertility (55.5% /18). A significant difference in intrauterine adhesions between both groups being detected only in secondary infertility group (p value =0.006). Conclusion: Outpatient preliminary and routine diagnostic office hysteroscopy may be a beneficial part of a primary and secondary infertility workup.","PeriodicalId":19389,"journal":{"name":"Obstetrics & Gynecology International Journal","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76043308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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