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Effect of Mangifera Indica (Mango) on Dental Caries: A Systematic Review. 芒果对龋齿的影响:系统综述。
IF 1.7 Q3 NUTRITION & DIETETICS Pub Date : 2023-11-18 eCollection Date: 2023-01-01 DOI: 10.1177/11786388231204200
Yasaman Salimi, Narges Tavahodi, Hamed Taheri, Maryam Masoudi, Matin Safari Modaber, Nozhan Azimi, Mohammed Namiq Amin, Mobina Bagharianlemraski, Reza Namadkolahi, Mozhgan Khorami, Mehrnaz Salahi, Pouyan Razavi, Parisa Behshood, Seyed Ali Mosaddad, Niloofar Deravi

The present study aimed to evaluate the effect of Mangifera indica (mango) on dental caries. The entire plant, including the leaves, fruit, roots, and flowers, has various therapeutic characteristics used for centuries to cure various illnesses. This systematic review aimed to identify an inexpensive, simple, and effective method of preventing and controlling dental caries. The search was performed among the studies written in English, the database of abstracts concentrating on the effects of Mangifera indica (Mango) on dental caries detected in Pubmed, Scopus, Google Scholar, and Central. In total, we find 37 articles. The relevant English language articles published up to August 2022 were collected, screened, and reviewed. Search words contained "Mangifera indica" and "dental caries" or "Streptococcus mutans" or "tooth demineralization." For our systematic review analysis, we included 3 randomized controlled trial studies studying a total of 130 people, of whom 110 were children aged 8 to 14 and 20 were adults aged 20 to 25. These experiments all employed mouthwash containing an extract from Mangifera indica. In conclusion, it has been proven in 2 separate studies that saliva's PH will increase significantly. In addition, a reduction of S. mutants has been observed in another research. Overall, it was concluded that mango extract mouthwash is highly effective in decreasing the bacteria that can cause dental caries. however, we firmly believe that conduction of more detailed in vivo studies regarding Mangifera indica implications in dental caries treatment is essentially needed for further confirmation.

本研究旨在评价芒果对龋病的治疗作用。整个植物,包括叶子、果实、根和花,具有多种治疗特性,几个世纪以来一直用于治疗各种疾病。本系统综述旨在寻找一种廉价、简单、有效的预防和控制龋齿的方法。检索是在Pubmed、Scopus、Google Scholar和Central中检测到的关于芒果对龋齿影响的摘要数据库中以英文撰写的研究中进行的。我们总共找到了37篇文章。收集到2022年8月为止发表的相关英文文章,进行筛选和评审。搜索词包括“芒果”、“龋齿”、“变形链球菌”或“牙齿脱矿”。在我们的系统评价分析中,我们纳入了3项随机对照试验研究,共研究了130人,其中110人为8至14岁的儿童,20人为20至25岁的成年人。这些实验都使用含有芒果提取物的漱口水。总之,两项独立的研究已经证明,唾液的PH值会显著升高。此外,在另一项研究中也观察到S.突变体的减少。总的来说,结论是芒果提取物漱口水对减少导致龋齿的细菌非常有效。然而,我们坚信,对芒果在龋齿治疗中的影响进行更详细的体内研究是必要的,以进一步证实。
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引用次数: 0
Dietary Diversity, Nutritional Status, and Associated Factors Among Pregnant Women in Their First Trimester of Pregnancy in Ambo District, Western Ethiopia. 埃塞俄比亚西部安博地区妊娠前三个月孕妇饮食多样性、营养状况及相关因素
IF 1.7 Q3 NUTRITION & DIETETICS Pub Date : 2023-08-22 eCollection Date: 2023-01-01 DOI: 10.1177/11786388231190515
Mitsiwat Abebe Gebremichael, Tefera Belachew Lema

Background: Poor dietary diversity and undernutrition is a major public health concern for pregnant mothers. Optimal dietary diversity is essential during pregnancy since nutritional deficiencies may have a significant impact on both the mother's and the fetus's health. Pregnant women in Ambo district had inadequate dietary diversity and were undernourished, but their status during the first trimester of pregnancy was not known. As a result, the objective of this research was to assess the dietary diversity, nutritional status, and associated factors among pregnant women in the Ambo district.

Methods: A community-based cross-sectional study design and a multi-stage sampling technique were used among 750 pregnant women. Data was gathered using a semi-structured questionnaire. The Food and Nutrition Technical Assistance questionnaire was modified to collect data on dietary diversity. The nutritional status of pregnant women was assessed by measuring the mid-upper arm circumference. First, descriptive statistics like mean, Standard deviation, frequency and percentage were used, then bivariable and, finally, multivariable logistic regression analysis was used to assess the association of the predictors with the outcome variable.

Result: The study revealed that 73.6% and 23.9% of pregnant women had low dietary diversity and were undernourished, respectively. Being in food secured household (AOR = 4.44, 95% CI: 2.14-9.15), having good knowledge (AOR = 3.32, 95% CI: 2.10-5.23) and favorable attitude toward nutrition and health (AOR = 1.71, 95% CI: 1.10-2.66) were significantly associated with dietary diversity, whereas household size (having 1-3 household members AOR = 6.59, 95% CI: 2.53-17.21, having 4-5 household members AOR = 5.62, 95% CI: 3.15-9.99), being in food secured household (AOR = 5.64, 95% CI: 2.79-11.38), having high dietary diversity (AOR = 8.49, 95% CI: 2.47-29.23), and having optimal practice on nutrition and health (AOR = 6.85, 95% CI: 3.23-14.55) were significantly associated with undernutrition (P < .05).

Conclusions: The current study revealed that pregnant women in the study area had inadequate dietary diversity practices and a high prevalence of undernutrition. Knowledge and attitude, and households' food security status were the predictors of dietary diversity, while household size, household food security status, dietary diversity and nutrition and health practice were predictors of undernutrition. Hence, behavior change communication needs to be designed to improve the dietary diversity and nutritional status of pregnant women.

饮食多样性差和营养不良是孕妇关注的主要公共卫生问题。最佳的饮食多样性在怀孕期间至关重要,因为营养缺乏可能会对母亲和胎儿的健康产生重大影响。安博区的孕妇饮食多样性不足,营养不良,但她们在怀孕前三个月的状况尚不清楚。因此,本研究的目的是评估安博地区孕妇的饮食多样性、营养状况和相关因素。在750名孕妇中采用了基于社区的横断面研究设计和多阶段抽样技术。使用半结构化问卷收集数据。对食品和营养技术援助调查表进行了修改,以收集有关饮食多样性的数据。通过测量中上臂围来评估孕妇的营养状况。首先,使用描述性统计,如平均值、标准差、频率和百分比,然后使用双变量,最后使用多变量逻辑回归分析来评估预测因素与结果变量的相关性。研究显示,73.6%和23.9%的孕妇饮食多样性低,营养不良。处于粮食保障家庭(AOR = 4.44,95%可信区间:2.14-9.15),具有良好的知识(AOR = 3.32,95%CI:2.10-5.23)和对营养和健康的良好态度(AOR = 1.71,95%CI:1.10-2.66)与饮食多样性显著相关,而家庭规模(1-3个家庭成员的AOR = 6.59,95%置信区间:2.53-17.21,有4-5名家庭成员AOR = 5.62,95%置信区间:3.15-9.99),处于粮食保障家庭(AOR = 5.64,95%CI:2.79-11.38),具有较高的饮食多样性(AOR = 8.49,95%CI:2.47-29.23),并在营养和健康方面具有最佳实践(AOR = 6.85,95%CI:3.23-14.55)与营养不良显著相关(P < .05)。目前的研究表明,研究地区的孕妇饮食多样性做法不足,营养不良的患病率很高。知识和态度以及家庭的粮食安全状况是饮食多样性的预测因素,而家庭规模、家庭粮食安全状况、饮食多样性以及营养和健康实践是营养不良的预测因素。因此,需要设计行为改变沟通,以改善孕妇的饮食多样性和营养状况。
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引用次数: 0
Effect of Educational Intervention Program on Self-Efficacy of Individuals with Type 2 Diabetes Mellitus in South-East, Nigeria. 教育干预计划对尼日利亚东南部 2 型糖尿病患者自我效能的影响。
IF 2.3 Q3 NUTRITION & DIETETICS Pub Date : 2023-06-22 eCollection Date: 2023-01-01 DOI: 10.1177/11786388231181965
Christiana Nkiru Okafor, Chinedu Charles Onyenekwe, Uchenna Prosper Okonkwo, Joseph Onuuwa Umunnah, Chukwuemeka Chukwubuikem Okoro, Ahaoma Victor Mbanuzuru, Ukamaka Elizabeth Agunwah, Chika Chioma Odira, Eucharia Ngozi Makata, Chinenye Mercy Nwankwo

Objectives: Diabetes Mellitus is a chronic disease, which requires a level of confidence among the sufferers in its management. This study investigated the effect of an educational intervention program on self-efficacy (SE) in diabetic individuals with type 2 diabetes mellitus in South-East, Nigeria.

Methods: The study was a quasi-experimental controlled study, comprising 382 individuals with type 2 DM selected, and assigned to intervention (IG) and control groups (CG). The instrument for data collection was the Stanford Chronic Disease Self-Efficacy Scale (SCDS). Pretest data were collected, and thereafter education on diabetes management was given to the IG group. The IG was followed up for 6 months. At the end of 6 months, post-test data were collected using the same instrument. Data were analyzed using Pearson Chi-square test statistics. A P-value less than .05 alpha level was considered significant.

Results: There was no statistically significant difference between the two groups before intervention. However, after 6 months of intervention, a significant proportion of participants' scores in IG moved from low to either moderate, or high SE in almost all the SE domains (P < .05.

Conclusions: There was an improvement in most domains of self-efficacy in the intervention group after 6 months of educational intervention.

目的:糖尿病是一种慢性疾病,需要患者对其管理有一定的信心。本研究调查了教育干预计划对尼日利亚东南部 2 型糖尿病患者自我效能感(SE)的影响:该研究是一项准实验性对照研究,选取了 382 名 2 型糖尿病患者,将其分为干预组(IG)和对照组(CG)。数据收集工具是斯坦福慢性病自我效能量表(SCDS)。在收集了预测试数据后,对干预组进行了糖尿病管理教育。对 IG 组进行了为期 6 个月的随访。6 个月后,使用相同的工具收集后测数据。数据采用皮尔逊卡方检验统计法进行分析。P值小于0.05的α水平被认为是显著的:结果:干预前,两组之间没有明显的统计学差异。然而,经过 6 个月的干预后,相当一部分参与者的 IG 分数在几乎所有的 SE 领域中都从低 SE 转为中 SE 或高 SE(P 结论:在大多数 SE 领域中,参与者的 IG 分数都有所提高:经过 6 个月的教育干预后,干预组在自我效能感的大部分领域都有所改善。
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引用次数: 0
Dietary Diversity and Haemoglobin Level Associated With Under Nutrition Among Pregnant Women at Sidama Hawassa, Ethiopia: Facility Based Cross-Sectional Study. 埃塞俄比亚 Sidama Hawassa 孕妇营养不良与膳食多样性和血红蛋白水平的关系:基于设施的横断面研究。
IF 2.3 Q3 NUTRITION & DIETETICS Pub Date : 2023-04-17 eCollection Date: 2023-01-01 DOI: 10.1177/11786388231165136
Tsegaye Alemu, Tigist Yakob, Tarekegn Solomon

Background: Under nutrition among pregnant women is common public health problem in developing countries including Ethiopia. It leads to poor maternal and neonatal outcomes. Despite its consequences there is shortage of research evidence to support intervention in this regard in the southern part of the country. Therefore, the aim of the study was to assess the determinates of under nutrition among pregnant women visiting antenatal care clinics at selected health facilities in Hawassa town.

Methods: Health facility based cross-sectional study was employed among 454 systematically selected study participants. Data were collected by using structured and pre-tested questionnaires with face to face interview. Data were entered into Epi info and then exported to SPSS version 26 statistical software for analysis. Data were analyzed with descriptive statistics; bivariate and multivariate binary logistic regression.

Result: The over all of prevalence of under nutrition among pregnant women was 27.6% [95% CI (22.6, 30.8)]. In multivariate logistic regression model, lowest wealth quintile [AOR = 3.3, 95% CI (1.7, 7.0)], women with dietary diversity [AOR = 2.0, 95% CI (1.3, 4.0)], presence of anemia [AOR = 10.7, 95% CI (5.8,19.8)], lower pregnant women education level [AOR = 3.3, 95% CI (1.4, 7.9)], lower partner education level [AOR = 3.1, 95% CI (1.1, 8.5)], not ate flush/meat food [AOR = 2.8, 95% CI (1.7, 4.8)], and not ate other fruits [AOR = 1.8, 95% CI (1.1, 2.8)] had significant association with under nutrition.

Conclusion: In this health facility based study, the burden of under nutrition was high. Lowest wealth quintiles, low dietary diversity scores, being anemic and low education of the pregnant women and her partner were associated with under nutrition. Therefore, counseling for dietary diversity during antenatal care, health promotion and education for pregnant women and empowering women on income generation activities are a key intervention to tackle under nutrition.

背景:孕妇营养不良是包括埃塞俄比亚在内的发展中国家普遍存在的公共卫生问题。它导致产妇和新生儿的不良后果。尽管营养不良会导致不良后果,但在埃塞俄比亚南部地区,缺乏研究证据来支持这方面的干预措施。因此,本研究旨在评估在哈瓦萨镇选定医疗机构产前护理诊所就诊的孕妇营养不良的决定因素。数据收集采用了结构化的、预先测试过的问卷,并进行了面对面的访谈。数据输入 Epi info,然后导出到 SPSS 26 版统计软件中进行分析。数据分析包括描述性统计、二元和多元二元逻辑回归:结果:孕妇营养不良的总体发生率为 27.6% [95% CI (22.6, 30.8)]。在多变量逻辑回归模型中,最低财富五分位数[AOR = 3.3,95% CI (1.7,7.0)]、膳食多样性[AOR = 2.0,95% CI (1.3,4.0)]、贫血[AOR = 10.7,95% CI (5.8,19.8)]、孕妇受教育程度较低[AOR = 3.3,95% CI (1.4,7.9)]、伴侣受教育程度较低[AOR = 3.1,95% CI (1.1,8.5)]、不吃冲调/肉类食物[AOR = 2.8,95% CI (1.7,4.8)]和不吃其他水果[AOR = 1.8,95% CI (1.1,2.8)]与营养不良有显著关联:在这项以医疗机构为基础的研究中,营养不良的负担很重。最低财富五分位数、膳食多样性得分低、贫血以及孕妇及其伴侣受教育程度低都与营养不良有关。因此,在产前护理期间提供饮食多样性咨询、对孕妇进行健康宣传和教育以及增强妇女创收活动的能力是解决营养不良问题的关键干预措施。
{"title":"Dietary Diversity and Haemoglobin Level Associated With Under Nutrition Among Pregnant Women at Sidama Hawassa, Ethiopia: Facility Based Cross-Sectional Study.","authors":"Tsegaye Alemu, Tigist Yakob, Tarekegn Solomon","doi":"10.1177/11786388231165136","DOIUrl":"10.1177/11786388231165136","url":null,"abstract":"<p><strong>Background: </strong>Under nutrition among pregnant women is common public health problem in developing countries including Ethiopia. It leads to poor maternal and neonatal outcomes. Despite its consequences there is shortage of research evidence to support intervention in this regard in the southern part of the country. Therefore, the aim of the study was to assess the determinates of under nutrition among pregnant women visiting antenatal care clinics at selected health facilities in Hawassa town.</p><p><strong>Methods: </strong>Health facility based cross-sectional study was employed among 454 systematically selected study participants. Data were collected by using structured and pre-tested questionnaires with face to face interview. Data were entered into Epi info and then exported to SPSS version 26 statistical software for analysis. Data were analyzed with descriptive statistics; bivariate and multivariate binary logistic regression.</p><p><strong>Result: </strong>The over all of prevalence of under nutrition among pregnant women was 27.6% [95% CI (22.6, 30.8)]. In multivariate logistic regression model, lowest wealth quintile [AOR = 3.3, 95% CI (1.7, 7.0)], women with dietary diversity [AOR = 2.0, 95% CI (1.3, 4.0)], presence of anemia [AOR = 10.7, 95% CI (5.8,19.8)], lower pregnant women education level [AOR = 3.3, 95% CI (1.4, 7.9)], lower partner education level [AOR = 3.1, 95% CI (1.1, 8.5)], not ate flush/meat food [AOR = 2.8, 95% CI (1.7, 4.8)], and not ate other fruits [AOR = 1.8, 95% CI (1.1, 2.8)] had significant association with under nutrition.</p><p><strong>Conclusion: </strong>In this health facility based study, the burden of under nutrition was high. Lowest wealth quintiles, low dietary diversity scores, being anemic and low education of the pregnant women and her partner were associated with under nutrition. Therefore, counseling for dietary diversity during antenatal care, health promotion and education for pregnant women and empowering women on income generation activities are a key intervention to tackle under nutrition.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"16 ","pages":"11786388231165136"},"PeriodicalIF":2.3,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/68/6c/10.1177_11786388231165136.PMC10114291.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9394117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Sex Hormone-Binding Globulin, Atherogenic Indices of Plasma Among Young Sedentary Males. 久坐不动的年轻男性血浆中性激素结合球蛋白与致动脉粥样硬化指数之间的关系
IF 2.3 Q3 NUTRITION & DIETETICS Pub Date : 2023-02-23 eCollection Date: 2023-01-01 DOI: 10.1177/11786388231155006
Ali Mohammadrezaei, Abnoos Mokhtari Ardekani, Mahdieh Abbasalizad-Farhangi, Mehran Mesgari-Abbasi, Reihaneh Mousavi

Background: Males are more likely than females to suffer from cardiovascular disease (CVD). So, sex hormones may modify these variations and affect the lipid profile. We examined the relationship between sex hormone-binding globulin (SHBG) and CVD risk factors among young males in this study.

Methods: Using a cross-sectional design, we measured total testosterone, SHBG, lipids, glucose, insulin, antioxidant parameters, and anthropometric factors in 48 young males in the age range of 18 to 40 years. Atherogenic indices of plasma were calculated. In this study, a partial correlation analysis was carried out to assess the relationship between SHBG and other variables after adjustment for confounders.

Results: According to the results of multivariable analyses adjusted for age and energy, SHBG had a negative correlation with total cholesterol (r = -.454, P =.010), low-density lipoprotein cholesterol (r = -.496, P =.005), quantitative insulin-sensitivity check index, and positive correlation with high-density lipoprotein cholesterol (r = .463, P =.009). No significant correlation was observed between SHBG and triglycerides (P >.05). Several atherogenic indices of plasma have a negative correlation with SHBG levels. These include Atherogenic Index of Plasma (r = -.474, P = .006), Castelli Risk Index (CRI)1 (r = -.581, P < .001), CRI2 (r = -.564, P = .001), and Atherogenic Coefficient (r = -.581, P < .001).

Conclusion: Among young men, high plasma SHBG was associated with reduced CVD risk factors, modified lipid profile and atherogenic ratios, and better glycemic markers. Therefore, reduced SHBG concentrations could be a prognostic marker of CVD among young sedentary males.

背景:男性比女性更容易罹患心血管疾病(CVD)。因此,性激素可能会改变这些变化并影响血脂状况。本研究探讨了性激素结合球蛋白(SHBG)与年轻男性心血管疾病风险因素之间的关系:我们采用横断面设计,测量了 48 名 18 至 40 岁年轻男性的总睾酮、SHBG、血脂、血糖、胰岛素、抗氧化参数和人体测量因素。计算了血浆中的致动脉粥样硬化指数。在这项研究中,对混杂因素进行调整后,进行了部分相关性分析,以评估 SHBG 与其他变量之间的关系:根据年龄和能量调整后的多变量分析结果,SHBG 与总胆固醇(r = -.454,P =.010)、低密度脂蛋白胆固醇(r = -.496,P =.005)、胰岛素敏感性定量检查指数呈负相关,与高密度脂蛋白胆固醇呈正相关(r = .463,P =.009)。在 SHBG 和甘油三酯之间没有观察到明显的相关性(P >.05)。血浆中的一些致动脉粥样硬化指数与 SHBG 水平呈负相关。这些指数包括血浆致动脉粥样硬化指数(r = -.474,P = .006)、卡斯泰利风险指数(CRI)1(r = -.581,P r = -.564,P = .001)和致动脉粥样硬化系数(r = -.581,P 结论:SHBG 与血浆致动脉粥样硬化指数呈负相关:在年轻男性中,高血浆 SHBG 与心血管疾病风险因素的减少、血脂状况和致动脉粥样硬化比率的改变以及血糖指标的改善有关。因此,SHBG浓度降低可能是久坐不动的年轻男性心血管疾病的预后标志。
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引用次数: 0
Antiviral Potential of Melissa officinalis L.: A Literature Review. Melissa officinalis L.的抗病毒潜力:文献综述。
IF 2.3 Q3 NUTRITION & DIETETICS Pub Date : 2023-01-12 eCollection Date: 2023-01-01 DOI: 10.1177/11786388221146683
Amirhossein Behzadi, Sadegh Imani, Niloofar Deravi, Zahra Mohammad Taheri, Fatemeh Mohammadian, Zahra Moraveji, Sepideh Shavysi, Motahareh Mostafaloo, Fateme Soleimani Hadidi, Sepehr Nanbakhsh, Sepehr Olangian-Tehrani, Mohammad Hesam Marabi, Parisa Behshood, Mohadeseh Poudineh, Ali Kheirandish, Kimia Keylani, Pooya Behfarnia

The use of synthetic drugs has increased in recent years; however, herbal medicine is yet more trusted among a huge population worldwide; This could be due to minimal side effects, affordable prices, and traditional beliefs. Lemongrass (Melissa officinalis) has been widely used for reducing stress and anxiety, increasing appetite and sleep, reducing pain, healing wounds, and treating poisonous insect bites and bee stings for a long time. Today, research has shown that this plant can also fight viruses including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Herpes Simplex Virus (HSV), and Human Immunodeficiency Virus (HIV) through various mechanisms such as inhibiting HSV-1 from binding to host cell, inhibiting HSV-1 replication during the post-adsorption or inhibiting main protease and spike protein of SARS-CoV-2, furthermore, be effective in treating related diseases. This Review investigated the antiviral properties of Melissa officinalis and its effect on viral diseases. More in vitro and in vivo studies are needed to determine Melissa officinaliss underlying mechanism, and more randomized controlled trials should be done to identify its effect in humans. Also, due to the usefulness and lack of side effects, it can be used more as a complementary medicine.

近年来,合成药物的使用越来越多;然而,草药却更受全世界广大民众的信赖;这可能是因为草药的副作用极小、价格实惠,而且具有传统观念。长期以来,柠檬草(Melissa officinalis)一直被广泛用于减轻压力和焦虑、增进食欲和睡眠、减轻疼痛、愈合伤口以及治疗毒虫叮咬和蜜蜂蛰伤。如今,研究表明这种植物也能通过各种机制抗病毒,包括严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)、单纯疱疹病毒(HSV)和人类免疫缺陷病毒(HIV),如抑制 HSV-1 与宿主细胞结合、抑制 HSV-1 在吸附后的复制或抑制 SARS-CoV-2 的主要蛋白酶和尖峰蛋白,并能有效治疗相关疾病。本综述研究了香蜂草的抗病毒特性及其对病毒性疾病的影响。要确定 Melissa officinaliss 的内在机制,还需要进行更多的体外和体内研究,并应进行更多的随机对照试验,以确定其对人体的作用。此外,由于其有用性和无副作用,可更多地将其用作辅助药物。
{"title":"Antiviral Potential of Melissa officinalis L.: A Literature Review.","authors":"Amirhossein Behzadi, Sadegh Imani, Niloofar Deravi, Zahra Mohammad Taheri, Fatemeh Mohammadian, Zahra Moraveji, Sepideh Shavysi, Motahareh Mostafaloo, Fateme Soleimani Hadidi, Sepehr Nanbakhsh, Sepehr Olangian-Tehrani, Mohammad Hesam Marabi, Parisa Behshood, Mohadeseh Poudineh, Ali Kheirandish, Kimia Keylani, Pooya Behfarnia","doi":"10.1177/11786388221146683","DOIUrl":"10.1177/11786388221146683","url":null,"abstract":"<p><p>The use of synthetic drugs has increased in recent years; however, herbal medicine is yet more trusted among a huge population worldwide; This could be due to minimal side effects, affordable prices, and traditional beliefs. Lemongrass (<i>Melissa officinalis</i>) has been widely used for reducing stress and anxiety, increasing appetite and sleep, reducing pain, healing wounds, and treating poisonous insect bites and bee stings for a long time. Today, research has shown that this plant can also fight viruses including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Herpes Simplex Virus (HSV), and Human Immunodeficiency Virus (HIV) through various mechanisms such as inhibiting HSV-1 from binding to host cell, inhibiting HSV-1 replication during the post-adsorption or inhibiting main protease and spike protein of SARS-CoV-2, furthermore, be effective in treating related diseases. This Review investigated the antiviral properties of <i>Melissa officinalis</i> and its effect on viral diseases. More in vitro and in vivo studies are needed to determine <i>Melissa officinaliss</i> underlying mechanism, and more randomized controlled trials should be done to identify its effect in humans. Also, due to the usefulness and lack of side effects, it can be used more as a complementary medicine.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"16 ","pages":"11786388221146683"},"PeriodicalIF":2.3,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/81/47/10.1177_11786388221146683.PMC9841880.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10551236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fermented Gluten-Free Multi-Grain Cereal Paste Development: The Role of the Orange-Fleshed Sweet Potato (OFSP) as a Dietary Supplement. 发酵无麸质杂粮糊的开发:橙肉甘薯(OFSP)作为膳食补充剂的作用
IF 1.7 Q3 NUTRITION & DIETETICS Pub Date : 2023-01-01 DOI: 10.1177/11786388231155007
Abiola Folakemi Olaniran, Clinton Emeka Okonkwo, Yetunde Mary Iranloye, Olajumoke Olubunmi Morakinyo, Abiola Ezekiel Taiwo, Oluwakemi Christianah Erinle, Oluwaseun Peter Bamidele, Oluwafemi Adeleke Ojo, Adekunbi Adetola Malomo, Omorefosa Osarenkhoe Osemwegie

Vitamin A deficiencies is a becoming persistent among young children and a growing concern to parents in sub-Saharan Africa, especially in crisis-affected areas. Fermented cereal paste from maize, millets, and sorghum grains are significant food for young children. Thus, the study focuses on food fortification using orange-fleshed sweet potato (OFSP) as fortifier as studies have confirmed the presence of nutrients that can help meet the Vitamin A dietary requirement. The cereals were soaked ambient temperature (27 ± 1°C) for 72 hours and were blended with OFSP (90:10, 80:20, 70:30, 60:40, 50:50), and the formulated products were studied for Vitamin A, β-carotene, proximate composition, physicochemical, functional properties, and storage. Application of OFSP as forticant increased the Vitamin A (4.98-6.65 mg/100 g), β-carotene (0.10-0.17 mg/100 g) and the calorific value (222.03-301.75 kcal) of the gluten-free multi-grain cereal paste. The addition of OFSP also increased the ash content (1.41%-3.35%), crude fiber (2.56%-4.225%), carbohydrate (39.83%-48.35%), total solid content (55.20%-60.87%), and water absorption capacity (112.20%-137.49%) of the formulated cereal samples. The fortified fermented paste was objectively stable throughout on the shelf from the storage studies. The study deduced that addition of orange-fleshed sweet potato to fermented mixed cereal paste as a fortifier can help increase the nutritional quality of the complementary food.

维生素A缺乏症在撒哈拉以南非洲,特别是受危机影响地区的幼儿中越来越普遍,也日益引起父母的关注。由玉米、小米和高粱谷物制成的发酵谷物糊是幼儿的重要食物。因此,研究的重点是食品强化使用橙皮甘薯(OFSP)作为强化剂,因为研究已经证实存在可以帮助满足维生素A饮食需求的营养物质。在室温(27±1℃)浸泡72小时后,与OFSP(90:10、80:20、70:30、60:40、50:50)混合,对配制后的谷物进行维生素A、β-胡萝卜素、近似组成、理化、功能特性和贮藏性能的研究。添加OFSP可提高无麸质杂粮糊的维生素A (4.98 ~ 6.65 mg/100 g)、β-胡萝卜素(0.10 ~ 0.17 mg/100 g)和发热量(222.03 ~ 301.75 kcal)。此外,OFSP的添加还提高了配方谷物样品的灰分含量(1.41% ~ 3.35%)、粗纤维含量(2.56% ~ 4.225%)、碳水化合物含量(39.83% ~ 48.35%)、总固含量(55.20% ~ 60.87%)和吸水率(112.20% ~ 137.49%)。从贮藏研究来看,强化发酵膏在货架上是客观稳定的。研究推断,在发酵的混合谷物糊中添加橙皮甘薯作为强化剂,有助于提高辅食的营养质量。
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引用次数: 1
Does Dietary Polyunsaturated Fatty Acid Intake Associate With Bone Mineral Density and Limb Structural Changes in Early Rheumatoid Arthritis? 饮食中多不饱和脂肪酸的摄入与早期类风湿关节炎的骨密度和肢体结构改变有关吗?
IF 1.7 Q3 NUTRITION & DIETETICS Pub Date : 2023-01-01 DOI: 10.1177/11786388231176169
Annika Valner, Raili Müller, Mart Kull, Kaja Põlluste, Margus Lember, Riina Kallikorm

Background: Rheumatoid arthritis (RA) is an inflammatory disease that can result in bone erosion, lean mass lowering, and increase of fat mass without changes in body weight. The dietary consumption of polyunsaturated fatty acids (PUFAs) has been assessed in many studies due to their potential anti-inflammatory effect.

Aim: The aim of this research was to identify if dietary intake of PUFAs associates with bone mineral density (BMD) and limb structural changes in early rheumatoid arthritis (ERA) compared to a population-based control group. The study was conducted because previous results have been insufficient.

Methods: The study group consisted of 83 ERA patients and 321 control subjects. A dual-energy X-Ray absorptiometry (DXA) machine was used to measure hip, lumbar spine, and radius BMD, as well as arm and leg fat, lean, and bone mass. Dietary habits and inflammatory markers were assessed to evaluate the effects to BMD and limb structural changes.

Results: In ERA subjects, higher dietary consumption of PUFAs was associated with a decrease in arm fat mass (b -28.17, P = .02) and possibly with higher lumbar BMD (b 0.008, P= .058). Limb bone and lean mass changes were not associated with dietary intake of PUFAs.

Conclusion: Balanced nutrition is essential. Consuming PUFAs could be beneficial in ERA preventing structural changes to hands, but additional research is needed.

背景:类风湿关节炎(RA)是一种炎症性疾病,可导致骨质侵蚀、瘦质量降低和脂肪量增加,而体重却没有变化。由于多不饱和脂肪酸(PUFAs)具有潜在的抗炎作用,因此在许多研究中对其膳食消耗进行了评估。目的:本研究的目的是确定与以人群为基础的对照组相比,膳食摄入PUFAs是否与早期类风湿关节炎(ERA)患者的骨矿物质密度(BMD)和肢体结构变化相关。之所以进行这项研究,是因为以前的结果不够充分。方法:研究组为ERA患者83例,对照组321例。采用双能x线骨密度仪(DXA)测量髋部、腰椎和桡骨骨密度,以及手臂和腿部脂肪、瘦骨量和骨量。评估饮食习惯和炎症标志物对骨密度和肢体结构变化的影响。结果:在ERA受试者中,较高的膳食摄取PUFAs与手臂脂肪量的减少(b -28.17, P = 0.02)以及可能与较高的腰椎骨密度(b 0.008, P = 0.058)相关。肢体骨和瘦肉质量的变化与膳食中PUFAs的摄入无关。结论:均衡营养至关重要。摄入pufa可能有助于ERA防止手部结构变化,但还需要进一步的研究。
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引用次数: 0
Protein Quality, Glycemic and Metabolic Indices and Anthropometric Features Among Overweight and Obese Adults. 超重和肥胖成人的蛋白质质量、血糖和代谢指数和人体测量特征。
IF 1.7 Q3 NUTRITION & DIETETICS Pub Date : 2023-01-01 DOI: 10.1177/11786388231181038
Ensiye Soleimani, Mahdieh Abbasalizad Farhangi

Background: Various studies have shown an inverse relationship between the quality of protein intake based on essential amino acids (EAAs) with obesity and its complications. We assumed that increasing EAAs-based protein intake quality improves glycemic and metabolic markers and anthropometric measurements in obese and overweight people.

Methods: This cross-sectional study included 180 obese and overweight participants aged 18 to 35. Dietary information was obtained using an 80-item food frequency questionnaire. The total intake of EAAs was calculated using the United States department of agriculture (USDA) database. Quality protein was defined as the ratio of EAAs (gr) to total dietary protein (gr). Sociodemographic status, physical activity (PA), and anthropometric characteristics were evaluated using a valid and reliable method. Analysis of covariance (ANCOVA) tests adjusted for sex, PA, age, energy, and body mass index (BMI) were used to measure this association.

Results: Protein quality intake was highest among the group with the lowest weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR), and fat mass (FM); and on the other hand, the fat-free mass (FFM) has increased; also Increasing the quality of protein intake improved the lipid profile and some glycemic indices and insulin sensitivity, although this association was not significant.

Conclusions: Increasing the quality of protein intake significantly improved anthropometric measurements, and also improved some glycemic and metabolic indices although, their relationship was not significant.

背景:各种研究表明,以必需氨基酸(EAAs)为基础的蛋白质摄入质量与肥胖及其并发症之间存在反比关系。我们假设增加基于easas的蛋白质摄入质量可以改善肥胖和超重人群的血糖和代谢指标以及人体测量值。方法:本横断面研究包括180名18至35岁的肥胖和超重参与者。饮食信息是通过80项食物频率问卷获得的。eaa的总摄入量是使用美国农业部(USDA)数据库计算的。优质蛋白质定义为EAAs (gr)与饲粮总蛋白质(gr)之比。使用有效可靠的方法评估社会人口状况、身体活动(PA)和人体测量特征。采用协方差分析(ANCOVA)检验校正性别、PA、年龄、能量和身体质量指数(BMI)来测量这种关联。结果:体重、体质指数(BMI)、腰围(WC)、臀围(HC)、腰臀比(WHR)、脂肪量(FM)最低组蛋白质质量摄取量最高;另一方面,无脂质量(FFM)增加;增加蛋白质摄入质量也改善了血脂和一些血糖指数以及胰岛素敏感性,尽管这种关联并不显著。结论:提高蛋白质摄入质量可显著改善人体测量指标,并可改善某些血糖和代谢指标,但两者之间的关系不显著。
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引用次数: 1
Impact of a Single Dose of a Probiotic Nutritional Supplement (AB001) on Absorption of Ethylalcohol: Results From a Randomized Double-Blind Crossover Study. 单剂量益生菌营养补充剂(AB001)对乙醇吸收的影响:来自随机双盲交叉研究的结果
IF 1.7 Q3 NUTRITION & DIETETICS Pub Date : 2023-01-01 DOI: 10.1177/11786388221141174
Andreas Pfützner, Anke Pfützner, Mina Hanna, Filiz Demircik, Daniela Sachsenheimer, Tobias Wittig, Johan de Faire

Background: We conducted a prospective placebo-controlled double-blind randomized Study to assess the impact of a single dose of a nutritional Supplement (AB001) on alcohol absorption in healthy subjects. Other objectives were the impact on breath alcohol content, cognitive function 1 hour after alcohol uptake and tolerability.

Method: A total of 24 healthy volunteers were enrolled into the study (12 male, 12 female, age: 28.3 ± 10.8 years, BMI: 23.5 ± 5.7 kg/m²). On the experimental day, they ingested a light breakfast together with a single dose (2 capsules) of AB001 (or placebo) and drank 2 moderate glasses of spirit (a total of 0.6 g/kg body weight). Breath alcohol tests and blood draws for determination of blood alcohol levels were performed for up to 6 hours. After crossover, the experiment was repeated in the following week. Areas under the curves were calculated to determine alcohol absorption rates.

Results: There was a significant reduction of blood alcohol by 10.1% (P < .001) with AB001, when compared to placebo. There was a less pronounced but also significant reduction of alcohol in the breath test by 7.2% (P < .05). No difference in the cognitive function test between AB001 and placebo could be observed 60 minutes after alcohol ingestion (22.6 ± 8.0 seconds vs 23.0 ± 11.2 seconds, n.s.). The supplement uptake was well tolerated and there were no adverse events related to the study intervention.

Conclusion: Uptake of a single dose of AB001 shortly before drinking alcohol significantly reduced plasma alcohol and breath alcohol concentrations, but the effect was less pronounced compared to chronic uptake as shown previously.

背景:我们进行了一项前瞻性安慰剂对照双盲随机研究,以评估单剂量营养补充剂(AB001)对健康受试者酒精吸收的影响。其他目标是对呼吸酒精含量、摄入酒精1小时后认知功能和耐受性的影响。方法:选取24名健康志愿者,其中男性12人,女性12人,年龄28.3±10.8岁,BMI 23.5±5.7 kg/m²。在实验当天,他们吃了一顿清淡的早餐,同时服用了单剂量(2粒胶囊)AB001(或安慰剂),并喝了2杯适量的烈酒(总计0.6 g/kg体重)。呼气酒精测试和抽血以确定血液酒精水平进行了长达6小时。交叉后,在接下来的一周内重复实验。计算曲线下的面积以确定酒精吸收率。结果:血液酒精浓度显著降低10.1% (P P结论:在饮酒前不久服用单剂量AB001可显著降低血浆酒精和呼气酒精浓度,但与之前所示的慢性服用相比,效果不那么明显。
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引用次数: 0
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Nutrition and Metabolic Insights
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