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An unusual presentation of Behçet’s disease with inferior vena cava thrombosis and pulmonary embolism behaperet病合并下腔静脉血栓和肺栓塞的不寻常表现
Pub Date : 2021-08-14 DOI: 10.4038/gmj.v26i2.8089
S. Karunanayaka, V. V. Jayawardhane, G. Premawansa
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引用次数: 0
Antibiotic use in poultry production; a cross-sectional study in a selected district in Sri Lanka 家禽生产中的抗生素使用;在斯里兰卡选定的一个地区进行的横断面研究
Pub Date : 2021-08-14 DOI: 10.4038/gmj.v26i2.8050
H. A. Ubeysekara, N. Ranaweera, H. H. Peris, W. Wijayaratne
Introduction: Rampant use of antibiotics in animal husbandry contributes significantly to the development and spread of antibiotic resistance. This study determines the antibiotic activity in poultry feed and assesses the knowledge on feeding practices and their potential effects on antimicrobial resistance among poultry farm owners. Methods: Poultry feed available for sale in shops and ready to serve poultry feed and water samples from selected farms in Kegalle District, Sri Lanka were tested for the antibiotic activity using the agar well diffusion method against three control organisms; Staphylococcus aureus ATCC25923, Escherichia coli ATCC25922 and Pseudomonas aeruginosa ATCC27853 and the zone of inhibition around each well was measured. All farm owners were interviewed and basic details regarding the farm such as area, number of animals, water source and the awareness of farm owners regarding antibiotic use in poultry feeds and water source were obtained. Results: No antibiotic activity was detected in commercially available poultry feed in selected shops (5/5) and ready to serve poultry feed in selected farms (18/18). An antibacterial effect was detected in water samples collected from 33.33% (6/18) of farms. Seventy-eight percent (14/18) of farm owners declared that they administer different types of additives containing antibiotics along with drinking water served to animals. Forty-four percent of farm owners believe that usage of antibiotics in poultry is not a good practice and harmful for human health while a similar percentage claim that it is a favorable practice as it benefits them economically. None of the farm owners were aware that the use of antibiotics in poultry can contribute to the increasing antibiotic resistance in the community. Conclusion: Commercially available poultry feeds in shops and ready to serve poultry feeds in farms did not demonstrate any antibiotic activity. However, antibiotic activity was detected in drinking water served to animals due to incorporation of antibiotic containing additives beyond the prevailing guidelines. The awareness of farm owners on antibiotic use in poultry and its effects on the increase of antibiotic resistance in the community is unsatisfactory.
导言:畜牧业中抗生素的滥用极大地促进了抗生素耐药性的发展和传播。本研究确定了家禽饲料中的抗生素活性,并评估了饲养实践知识及其对家禽养殖场主抗菌素耐药性的潜在影响。方法:采用琼脂孔扩散法对斯里兰卡Kegalle区选定农场的家禽饲料和水样进行抗生素活性测试,检测商店出售的家禽饲料和准备供应的家禽饲料和水样对三种对照生物的抗生素活性;测定金黄色葡萄球菌ATCC25923、大肠杆菌ATCC25922和铜绿假单胞菌ATCC27853及其各孔周围的抑制区。对所有农场主进行了访谈,并获得了有关农场的基本细节,如面积、动物数量、水源以及农场主对家禽饲料和水源中抗生素使用的认识。结果:选定商店(5/5)的市售家禽饲料和选定农场(18/18)的待售家禽饲料均未检出抗生素活性。33.33%(6/18)的养殖场水样检测出抗菌效果。78%(14/18)的农场主声称,他们在给动物提供的饮用水中添加了不同类型的含有抗生素的添加剂。44%的农场主认为,在家禽中使用抗生素不是一种好的做法,对人类健康有害,而同样比例的农场主声称,这是一种有利的做法,因为它在经济上有利于他们。没有一个农场主意识到在家禽中使用抗生素会导致社区中抗生素耐药性的增加。结论:商店的市售家禽饲料和农场的即食家禽饲料未显示出任何抗生素活性。然而,在提供给动物的饮用水中检测到抗生素活性,这是由于添加了超出现行准则的含抗生素添加剂。养殖户对家禽抗生素使用的认识及其对社区抗生素耐药性增加的影响并不令人满意。
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引用次数: 0
Compromising patient safety: Lessons learnt from some critical incidents 危及患者安全:从一些重大事件中吸取的教训
Pub Date : 2021-08-14 DOI: 10.4038/gmj.v26i2.8069
P. L. Ariyananda
During my professional career as a clinician for nearly five decades, I have come across several instances where I felt that my role as a clinician has been a failure. I consider these instances as critical incidents that have molded my clinical practice and hopefully made me a better clinician. In this paper, I will discuss about few of those situations, narrating the experience that I lived through, highlighting where I think I went wrong and how best we clinicians should perform under such circumstances. I have divided the paper into lapses in history taking, lack of completeness in physical examination, premature closure in making a diagnosis and inadequacies in treatment, and each of these will be illustrated using a real-life scenario that I have lived through. As clinicians, we should strive for zero error, but we human beings are imperfect and often have room for improvement in the ways we act and react. In your clinical practice, irrespective of whether you experience critical incidents or not, it is always better to reflect how you could have treated each patient you have seen, better and make your practice more reflective rather than thinking in a stereotyped manner.
在我近五十年的临床医生职业生涯中,我遇到过几个例子,我觉得我作为临床医生的角色是失败的。我认为这些重要的事件塑造了我的临床实践,并希望使我成为一个更好的临床医生。在本文中,我将讨论其中的一些情况,叙述我的经历,强调我认为我做错了什么,以及我们临床医生在这种情况下应该如何表现得最好。我将这篇论文分为以下几部分:历史研究的失误、体检的不完整、诊断的过早结束和治疗的不充分,每一项都将用我经历过的一个现实生活场景来说明。作为临床医生,我们应该努力实现零错误,但我们人类是不完美的,我们的行为和反应方式往往还有改进的余地。在你的临床实践中,无论你是否经历过重大事件,最好总是反思你本可以如何治疗你所见过的每一个病人,更好地使你的实践更具反思性,而不是以刻板的方式思考。
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引用次数: 0
Save the children from screen overuse 避免孩子过度使用屏幕
Pub Date : 2021-08-14 DOI: 10.4038/gmj.v26i2.8085
N. Liyanarachchi
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引用次数: 0
Physiological profile of Sri Lankan male long distance runners and sprinters competing at national level and university level; a descriptive study 斯里兰卡男子国家级和高校长跑、短跑运动员的生理特征描述性研究
Pub Date : 2021-08-14 DOI: 10.4038/gmj.v26i2.8087
K. Wijayasiri, S. Wimalasekera, S. Sivayogan, H. Waidyasekara, Y. Ishikawa
Introduction: Despite regular training Sri Lankan runners do not perform well in international sports arena. The performance of a runner is determined by cardiopulmonary fitness level. However, little is known about the cardiopulmonary fitness levels of Sri Lankan runners. Thus, the present study was conducted to assess the status of the cardiopulmonary fitness of a group of Sri Lankan national level and university level male long distance runners and sprinters. Methods: A descriptive cross-sectional study was conducted to determine the baseline data using interviewer administered questionnaire and clinical examination of 95 male runners [national level long distance runners (n = 27), national level sprinters (n = 27), university level long distance runners (n = 20), university level sprinters (n = 21)] and age and sex matched control subjects (n = 41). Cardiopulmonary exercise fitness was assessed by a fully automated Cardiopulmonary Exercise Testing (CPET) machine. Results: The CPET parameters such as VO , peak workload, exercise duration, heart rate at rest (HR ) and 2max rest at peak (HR ), systolic blood pressure at rest (SBP ), and at peak (SBP ), diastolic blood pressure at peak rest peak rest (DBP ), and at peak (DBP ) amongst Sri Lankan national level runners indicated minimal improvement rest peak when compared to Sri Lankan university level runners. Further, most of the CPET parameters of Sri Lankan runners were lower when compared with those parameters of runners from the Asian region. Conclusions and recommendations: Cardiopulmonary fitness of Sri Lankan long distance runners and sprinters is low. Thus, training protocols are needed to be modified in accordance with the baseline CPET parameters to attain optimal cardiovascular remodelling to enhance he performance of Sri Lankan runners.
导读:尽管定期训练,斯里兰卡跑步运动员在国际竞技场上的表现并不好。跑步者的表现是由心肺健康水平决定的。然而,人们对斯里兰卡跑步者的心肺健康水平知之甚少。因此,本研究旨在评估一组斯里兰卡国家级和大学级男性长跑运动员和短跑运动员的心肺健康状况。方法:采用描述性横断面研究方法,对95名男性跑步者[国家级长跑运动员(27名)、国家级短跑运动员(27名)、大学级长跑运动员(20名)、大学级短跑运动员(21名)]和年龄、性别匹配的对照组(41名)进行问卷调查和临床检查,确定基线数据。采用全自动心肺运动测试(CPET)机评估心肺运动适能。结果:斯里兰卡国家级跑者的CPET参数如VO、峰值负荷、运动持续时间、静息心率(HR)和2max静息峰值心率(HR)、静息收缩压(SBP)和峰值收缩压(SBP)、静息舒张压(DBP)和峰值舒张压(DBP)与斯里兰卡大学水平跑者相比,静息峰值改善最小。此外,斯里兰卡跑者的大部分CPET参数都低于亚洲地区的跑者。结论和建议:斯里兰卡长跑运动员和短跑运动员的心肺健康水平较低。因此,训练方案需要根据基线CPET参数进行修改,以达到最佳的心血管重塑,以提高斯里兰卡跑步者的表现。
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引用次数: 0
Towards frontiers of human endurance: Evolving role of sports medicine 走向人类耐力的前沿:运动医学的演变角色
Pub Date : 2021-08-14 DOI: 10.4038/gmj.v26i2.8084
S. Goonesinghe, E. Waidyarathne
In their paper on the physiological profile of male long-distance runners and sprinters, Wijayasiri et al., focuses on Sri Lankan athletes of two different types of running events and their cardiopulmonary fitness. Structured exercise and training bring about enhanced performance. The use of unauthorized enhancement medication with the connivance of medical doctors, sport bodies and in some instances states has become a dangerous trend in the world. It is abhorrent from a sporting perspective; unethical from a professional perspective and harmful to health of athletes from a medical perspective.
Wijayasiri等人在他们关于男性长跑运动员和短跑运动员生理特征的论文中,重点关注了斯里兰卡两种不同类型跑步项目的运动员及其心肺健康状况。有组织的锻炼和训练可以提高表现。在医生、体育机构和某些情况下国家的默许下使用未经授权的增强药物已成为世界上一种危险的趋势。从体育的角度来看,这是令人憎恶的;从专业角度看是不道德的,从医学角度看是有害运动员健康的。
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引用次数: 0
Bacterial wound infections leading to bacteraemia with Vibrio vulnificus and Morganella morganii; two unusual cases 细菌性伤口感染导致创伤弧菌和摩根氏菌菌血症;两个不同寻常的案例
Pub Date : 2021-07-26 DOI: 10.4038/gmj.v26i1.8082
D. Piyasiri, A. Kirubaharan, I. Nanayakkara, J. Jayasekara, M. Galhenage, P. Sapukotana
She was afebrile on admission, however, developed redness and swelling at the cannula site few days later. Next day, she fell in the hospital toilet and landed on the infected forearm. This toilet was a squatting type with water sourced from the local municipal council supply. There was no visible faecal contamination. Three days later, she developed severe infection with blister formation at the infected site with high fever spikes (Figure 1). There was no history of any local treatment to the site including ayurvedic preparations or salt.
患者入院时发热,但几天后插管部位出现红肿。第二天,她在医院的厕所里摔倒了,落在了感染的前臂上。这个厕所是蹲式的,水来自当地市政委员会的供应。没有明显的粪便污染。3天后,患者出现严重感染,感染部位形成水疱并伴有高热尖峰(图1)。该部位没有任何局部治疗史,包括阿育吠陀制剂或盐。
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引用次数: 0
How Australia deals with suicides: lessons learnt and implications for Sri Lanka 澳大利亚如何处理自杀:经验教训和对斯里兰卡的启示
Pub Date : 2021-07-26 DOI: 10.4038/gmj.v26i1.8076
A. Chandrasiri
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引用次数: 0
In-vitro evaluation of bactericidal activity of antiseptics and disinfectants commonly used in healthcare settings 医疗机构常用的防腐剂和消毒剂杀菌活性的体外评价
Pub Date : 2021-07-26 DOI: 10.4038/gmj.v26i1.8079
K. C. Perera, S. K. Ekanayaka, N. Chandrasiri, K. Jayatilleke, J. Kottahachchi
Introduction: Healthcare-associated infections are common problems found in healthcare systems in most of the countries. Proper use of antiseptics and disinfectants is useful in reducing the magnitude of such infections. The aim of this study was to evaluate the bactericidal effect of different concentrations of selected antiseptics and disinfectants. Methods: Bactericidal activity of different concentrations of antiseptics and disinfectants; isopropyl alcohol, povidone iodine, chlorhexidine gluconate, sodium hypochlorite, hypertonic saline, peracetic acid and mixture of 2-aminoethanol, dodecyl dimethyl ammonium chloride, potassium carbonate & bis(3-aminopropyl) dodecylamine were evaluated against nine strains of American Type Culture Collections and 11 strains isolated from the hospitals. Bacterial suspensions were prepared equal to 0.5 McFarland turbidity standards and 100 μl of each was mixed with 3 ml of antiseptic/ disinfectant solution. After desired contact time (1 minute, 15 minutes and 24 hours), 20 μl of reaction mixer was transferred into 4 ml of sterile physiological saline, mixed well and 20 μl of solution was evenly spread throughout Muller Hinton agar/ blood agar plates. Growth control was done using 3 ml of distilled water instead of 3 ml of antiseptic/ disinfectant solution. All plates incubated at 35oC ± 2oC for 18 – 24 hours. Colonies were counted and reduction percentage was calculated. Results: All concentrations of isopropyl alcohol, povidone iodine, chorhexidine, sodium hypochlorite, peracetic acid and the mixture of 2-aminoethanol, didecyldimethylammonium chloride, potassium carbonate and bis(3-aminopropyl)dodecylamine showed 100% bactericidal activities against all tested bacterial strains in1-minute contact time. Bactericidal activity of hypertonic saline was varied against tested bacterial strains with higher bactericidal activity against Gram positive organisms than Gram negative organisms. Conclusions: Currently using concentrations of antiseptics and disinfectants evaluated in this study have 100% bactericidal activity other than hypertonic saline.
卫生保健相关感染是大多数国家卫生保健系统中发现的常见问题。正确使用防腐剂和消毒剂有助于减少此类感染的严重程度。本研究的目的是评价选定的不同浓度的防腐剂和消毒剂的杀菌效果。方法:测定不同浓度的防腐剂和消毒剂的杀菌活性;用异丙醇、聚维酮碘、葡萄糖酸氯己定、次氯酸钠、高渗盐水、过氧乙酸和2-氨基乙醇、十二烷基二甲基氯化铵、碳酸钾和双(3-氨基丙基)十二胺的混合物对美国型培养收集的9株菌株和医院分离的11株菌株进行评价。取按0.5麦克法兰浊度标准配制的菌悬液,各取100 μl与3ml消毒液混合。待所需接触时间(1分钟、15分钟和24小时)后,将20 μl反应混合液加入4 ml无菌生理盐水中,混合均匀,将20 μl溶液均匀涂抹在Muller Hinton琼脂/血琼脂平板上。用3ml蒸馏水代替3ml杀菌/消毒液控制生长。所有板在35℃±20℃下孵育18 - 24小时。计数菌落,计算减少率。结果:所有浓度的异丙醇、聚维酮碘、氯己定、次氯酸钠、过氧乙酸以及2-氨基乙醇、二癸基二甲基氯化铵、碳酸钾和双(3-氨基丙基)十二烷基胺的混合物在1分钟内对所有被试菌株都有100%的杀菌活性。高渗盐水对革兰氏阳性菌的杀菌活性高于革兰氏阴性菌。结论:在本研究中评估的目前使用的防腐剂和消毒剂浓度除高渗盐水外具有100%的杀菌活性。
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引用次数: 0
Recurrent vomiting in a toddler; oesophageal food bolus impaction 幼儿反复呕吐;食道食物堵塞
Pub Date : 2021-07-26 DOI: 10.4038/GMJ.V26I1.8081
V. P. Sinhabahu, S. Jamison, S. Cunninghams
Vomiting is common in children. Vomiting or emesis, is the actual oral expulsion of gastrointestinal contents as a result of contractions of the gastrointestinal and the thoracoabdominal wall musculature (1). Vomiting centre in medulla oblongata comprises of reticular formation and the nucleus of the tractus solitarius. Motor pathways descend from vomiting centre trigger vomiting when stimulated. These efferent pathways travel th th th th th within the 5 , 7 , 9 , 10 , and 12 cranial nerves to the upper gastrointestinal tract, within vagal and sympathetic nerves to the lower tract, and within spinal nerves to the diaphragm and abdominal muscles. The vomiting centre can be activated directly by irritants or indirectly following input from four principal areas: gastrointestinal tract, cerebral cortex and thalamus, vestibular region, and chemoreceptor trigger zone (CRTZ) (1). Local causes such as gastrointestinal infection or obstruction, pharyngitis and systemic causes such as sepsis, increased intracranial pressure and chemotherapy can give rise to repeated episodes of vomiting by triggering the vomiting centre. Oesophageal food bolus is a rare cause of vomiting in children (2). One study had estimated that the incidence of upper gastrointestinal food bolus impaction is 13 per 100,000 populations (3). More than 80% of children with oesophageal food bolus impaction have an abnormality in the oesophagus (2). We describe a case of a toddler with recurrent vomiting due to oesophageal food bolus impaction. Case presentation
呕吐在儿童中很常见。呕吐或呕吐是胃肠道和胸腹壁肌肉组织收缩导致的胃肠道内容物的实际口腔排出(1)。延髓的呕吐中心由网状结构和孤束核组成。当受到刺激时,从呕吐中枢下行的运动通路触发呕吐。这些传出通路在5、7、9、10和12脑神经中传递到上胃肠道,在迷走神经和交感神经中传递到下胃肠道,在脊神经中传递到横膈膜和腹肌。呕吐中枢可由刺激物直接激活,也可由以下四个主要区域间接激活:胃肠道、大脑皮层和丘脑、前庭区和化学感受器触发区(CRTZ)(1)。局部原因如胃肠道感染或梗阻、咽炎和全身性原因如败血症、颅内压升高和化疗可通过触发呕吐中枢引起呕吐反复发作。食道食物丸是一种罕见的儿童呕吐原因(2)。一项研究估计,上胃肠道食物丸嵌塞的发生率为每10万人中有13人(3)。超过80%的食道食物丸嵌塞儿童食道异常(2)。我们描述了一个因食道食物丸嵌塞而反复呕吐的幼儿病例。案例展示
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引用次数: 0
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Galle Medical Journal
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