Aimann Surak, Georg M Schmölzer, Khorshid Mohammad
Neonatal cerebral hemodynamics represents a complex process affected by dynamic circulatory changes. Understanding the pathophysiology and factors that may affect cerebral blood flow in neonates is crucial to addressing the circulatory mechanism for neonatal brain injury. Studies have described multiple tools for monitoring cerebral blood flow; however, these are limited by the impracticality of using invasive tools. In this review, we explain the physiology of neonatal cerebral autoregulation with a focus on the transitional period and summarize the currently available methods for monitoring.
{"title":"Cerebral Autoregulation in Neonates: Physiology and Beyond.","authors":"Aimann Surak, Georg M Schmölzer, Khorshid Mohammad","doi":"10.1542/neo.26-7-033","DOIUrl":"https://doi.org/10.1542/neo.26-7-033","url":null,"abstract":"<p><p>Neonatal cerebral hemodynamics represents a complex process affected by dynamic circulatory changes. Understanding the pathophysiology and factors that may affect cerebral blood flow in neonates is crucial to addressing the circulatory mechanism for neonatal brain injury. Studies have described multiple tools for monitoring cerebral blood flow; however, these are limited by the impracticality of using invasive tools. In this review, we explain the physiology of neonatal cerebral autoregulation with a focus on the transitional period and summarize the currently available methods for monitoring.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"26 7","pages":"e463-e476"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Collaboration Between Cardiology and Palliative Care for Severe Congenital Heart Disease.","authors":"Karen Texter, Oluseyi Ogunleye, Adolfo Etchegaray, Amy Schlegel","doi":"10.1542/neo.26-7-039","DOIUrl":"https://doi.org/10.1542/neo.26-7-039","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"26 7","pages":"e511-e515"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Theresa Urbina, Brittany Graham, Richard Tang, Sheria D Wilson, Aura A Sanchez Mejia, Sharada H Gowda
See bonus neobriefs videos and downloadable teaching slides on this article’s homepage:
Double outlet right ventricle (DORV) is a complex congenital heart disease with a wide spectrum of anatomical variations and clinical presentations. In this conotruncal anomaly, greater than 50% of the semilunar valve diameter of both the aorta and pulmonary artery arises from the morphologic right ventricle. Additionally, patients with DORV have a ventricular septal defect that allows blood to egress from the left ventricle and may obstruct either the pulmonary or systemic circulations. Physiological characteristics differ among patients based on the orientation of the great arteries, the presence of additional intracardiac shunts, and cardiac abnormalities. A thorough understanding of an individual's clinical features based on their DORV phenotype is essential for clinicians caring for these vulnerable patients. Knowledge of the expected postnatal hemodynamic derangements as transitional physiology evolves allows for tailored therapeutic approaches at the bedside. In this review, we will discuss the main DORV subtypes, delineate the physiology of each subtype, and provide clinical considerations and medical management strategies to guide the care for patients with this complex cardiac lesion.
{"title":"Congenital Conundrum: Unraveling the Puzzle of Double Outlet Right Ventricle for the Neonatologist.","authors":"Theresa Urbina, Brittany Graham, Richard Tang, Sheria D Wilson, Aura A Sanchez Mejia, Sharada H Gowda","doi":"10.1542/neo.26-7-034","DOIUrl":"https://doi.org/10.1542/neo.26-7-034","url":null,"abstract":"<p><strong>See bonus neobriefs videos and downloadable teaching slides on this article’s homepage: </strong></p><p><p>Double outlet right ventricle (DORV) is a complex congenital heart disease with a wide spectrum of anatomical variations and clinical presentations. In this conotruncal anomaly, greater than 50% of the semilunar valve diameter of both the aorta and pulmonary artery arises from the morphologic right ventricle. Additionally, patients with DORV have a ventricular septal defect that allows blood to egress from the left ventricle and may obstruct either the pulmonary or systemic circulations. Physiological characteristics differ among patients based on the orientation of the great arteries, the presence of additional intracardiac shunts, and cardiac abnormalities. A thorough understanding of an individual's clinical features based on their DORV phenotype is essential for clinicians caring for these vulnerable patients. Knowledge of the expected postnatal hemodynamic derangements as transitional physiology evolves allows for tailored therapeutic approaches at the bedside. In this review, we will discuss the main DORV subtypes, delineate the physiology of each subtype, and provide clinical considerations and medical management strategies to guide the care for patients with this complex cardiac lesion.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"26 7","pages":"e477-e489"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paige E Condit, Tyler L King, Amy H Stanford, Dinushan C Kaluarachchi, Patrick J McNamara
{"title":"Hemodynamic Precision in the Management of Vein of Galen Aneurysmal Malformations.","authors":"Paige E Condit, Tyler L King, Amy H Stanford, Dinushan C Kaluarachchi, Patrick J McNamara","doi":"10.1542/neo.26-7-032","DOIUrl":"https://doi.org/10.1542/neo.26-7-032","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"26 7","pages":"e451-e462"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jermine Harriet Romald, Priya Tiwari, Lovya George
{"title":"Outcome of a Late Preterm Infant With Prenatally Diagnosed Vein of Galen Malformation.","authors":"Jermine Harriet Romald, Priya Tiwari, Lovya George","doi":"10.1542/neo.26-7-040","DOIUrl":"https://doi.org/10.1542/neo.26-7-040","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"26 7","pages":"e516-e523"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epilepsy in Pregnancy.","authors":"Giuliana Rivera Casul, Brett C Young","doi":"10.1542/neo.26-7-037","DOIUrl":"https://doi.org/10.1542/neo.26-7-037","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"26 7","pages":"e499-e504"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Specialists in neonatal hemodynamics have great potential to revolutionize the approach to hospitalized neonates with hemodynamic instability. Involvement of bedside nurses, advanced practice nurses, and advanced practice clinicians is critical to the success of caring for these infants. In this article, we describe a roadmap to involve nursing staff in the initiation and maintenance of neonatal hemodynamics programs in the neonatal intensive care unit.
{"title":"Role of Nursing in Initiation and Maintenance of a Neonatal Hemodynamics Program.","authors":"Ruth M Teesdale","doi":"10.1542/neo.26-7-031","DOIUrl":"10.1542/neo.26-7-031","url":null,"abstract":"<p><p>Specialists in neonatal hemodynamics have great potential to revolutionize the approach to hospitalized neonates with hemodynamic instability. Involvement of bedside nurses, advanced practice nurses, and advanced practice clinicians is critical to the success of caring for these infants. In this article, we describe a roadmap to involve nursing staff in the initiation and maintenance of neonatal hemodynamics programs in the neonatal intensive care unit.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"26 7","pages":"e446-e450"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Severe visual impairment in the newborn period can be attributed to prenatal and perinatal etiologies. Prenatal causes include various congenital anomalies such as anophthalmos or microphthalmos, congenital cataracts, congenital glaucoma, retinal dystrophies, and retinoblastoma. Acquired perinatal causes include ophthalmia neonatorum, cerebral visual impairment related to neurologic insult, and retinopathy of prematurity. Severe visual impairment can negatively affect a child's growth, development, social skills, and educational abilities, but prompt recognition and treatment of visual deficits can minimize long-term complications. In this review, we describe the approach to screening for visual impairment in the newborn and review treatment modalities and long-term sequelae of the most common causes of neonatal visual impairment.
{"title":"Neonatal Visual Impairment: Etiologies, Screening, and Management.","authors":"Lydia Vielmetti, Shayna Hibbs, Hawke Yoon","doi":"10.1542/neo.26-6-023","DOIUrl":"https://doi.org/10.1542/neo.26-6-023","url":null,"abstract":"<p><p>Severe visual impairment in the newborn period can be attributed to prenatal and perinatal etiologies. Prenatal causes include various congenital anomalies such as anophthalmos or microphthalmos, congenital cataracts, congenital glaucoma, retinal dystrophies, and retinoblastoma. Acquired perinatal causes include ophthalmia neonatorum, cerebral visual impairment related to neurologic insult, and retinopathy of prematurity. Severe visual impairment can negatively affect a child's growth, development, social skills, and educational abilities, but prompt recognition and treatment of visual deficits can minimize long-term complications. In this review, we describe the approach to screening for visual impairment in the newborn and review treatment modalities and long-term sequelae of the most common causes of neonatal visual impairment.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"26 6","pages":"e391-e401"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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