Pub Date : 1982-11-01DOI: 10.1097/00006534-198211000-00093
W. M. Ringsdorf, E. Cheraskin
Clinical studies provide evidence that wound healing in subjects judged not deficient in vitamin C can be significantly accelerated with supplements of this nutrient above the recommended daily allowance (RDA). The authors administered daily dosages of 500 to 3,000 mg., which is roughly 8 to 50 times the RDA of 60 mg., to subjects recovering from surgery, other injuries, decubital ulcers, and leg ulcers induced by hemolytic anemia. Genetic impairment of collagen synthesis has also been observed to be responsive to ascorbic acid supplementation in an 8-year-old boy with Type VI Ehlers-Danlos syndrome. Four grams of ascorbic acid daily produced a significant improvement in the quality of newly synthesized collagen but did not alter that formed prior to the supplementation of C. The combined evidence in this review provides a substantial base for further research, both clinical and experimental trials, concerning the interrelationships between vitamin C and the body's healing potential.
{"title":"Vitamin C and human wound healing.","authors":"W. M. Ringsdorf, E. Cheraskin","doi":"10.1097/00006534-198211000-00093","DOIUrl":"https://doi.org/10.1097/00006534-198211000-00093","url":null,"abstract":"Clinical studies provide evidence that wound healing in subjects judged not deficient in vitamin C can be significantly accelerated with supplements of this nutrient above the recommended daily allowance (RDA). The authors administered daily dosages of 500 to 3,000 mg., which is roughly 8 to 50 times the RDA of 60 mg., to subjects recovering from surgery, other injuries, decubital ulcers, and leg ulcers induced by hemolytic anemia. Genetic impairment of collagen synthesis has also been observed to be responsive to ascorbic acid supplementation in an 8-year-old boy with Type VI Ehlers-Danlos syndrome. Four grams of ascorbic acid daily produced a significant improvement in the quality of newly synthesized collagen but did not alter that formed prior to the supplementation of C. The combined evidence in this review provides a substantial base for further research, both clinical and experimental trials, concerning the interrelationships between vitamin C and the body's healing potential.","PeriodicalId":19675,"journal":{"name":"Oral surgery, oral medicine, and oral pathology","volume":"9 1","pages":"231-6"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88458119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1982-02-01DOI: 10.1097/00006534-198202000-00058
D. A. Bussard, G. Kerr, C. Hutton, H. Yune
In diagnosing and treating temporomandibular joint (TMJ) dysfunctions, the oral and maxillofacial surgeon can use the radiographic technique of "corrected-axis" lateral tomography of the mandibular condyles. The theory, technique, and equipment necessary for making "corrected-axis" lateral tomograms of the mandibular condyles are presented. Once familiar with this technique, the surgeon can educate the radiologist and technician if it is one with which they are unfamiliar.
{"title":"Technique and use of \"corrected-axis\" tomograms of the mandibular condyles.","authors":"D. A. Bussard, G. Kerr, C. Hutton, H. Yune","doi":"10.1097/00006534-198202000-00058","DOIUrl":"https://doi.org/10.1097/00006534-198202000-00058","url":null,"abstract":"In diagnosing and treating temporomandibular joint (TMJ) dysfunctions, the oral and maxillofacial surgeon can use the radiographic technique of \"corrected-axis\" lateral tomography of the mandibular condyles. The theory, technique, and equipment necessary for making \"corrected-axis\" lateral tomograms of the mandibular condyles are presented. Once familiar with this technique, the surgeon can educate the radiologist and technician if it is one with which they are unfamiliar.","PeriodicalId":19675,"journal":{"name":"Oral surgery, oral medicine, and oral pathology","volume":"31 1","pages":"394-7"},"PeriodicalIF":0.0,"publicationDate":"1982-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73780986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pyostomatitis vegetans.","authors":"E. Cataldo, M. Covino, P. E. Tesone","doi":"10.1055/b-0034-55866","DOIUrl":"https://doi.org/10.1055/b-0034-55866","url":null,"abstract":"","PeriodicalId":19675,"journal":{"name":"Oral surgery, oral medicine, and oral pathology","volume":"48 1","pages":"172-7"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85387750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1980-06-01DOI: 10.1097/00006534-198112000-00060
I. Small, H. Shandler, M. Husain, H. David
A girl with a family history of Gardner's syndrome presented with an actively growing central lesion of the mandible and localized subcutaneous fibrous hyperplasia which required surgical intervention and bone grafting. The importance of this syndrome is the development of intestinal polyposis which become malignant. The presence of dentofacial stigmata and surface tumors should alert the dentist and physician to the possibility of Gardner's syndrome.
{"title":"Gardner's syndrome with an unusual fibro-osseous lesion of the mandible.","authors":"I. Small, H. Shandler, M. Husain, H. David","doi":"10.1097/00006534-198112000-00060","DOIUrl":"https://doi.org/10.1097/00006534-198112000-00060","url":null,"abstract":"A girl with a family history of Gardner's syndrome presented with an actively growing central lesion of the mandible and localized subcutaneous fibrous hyperplasia which required surgical intervention and bone grafting. The importance of this syndrome is the development of intestinal polyposis which become malignant. The presence of dentofacial stigmata and surface tumors should alert the dentist and physician to the possibility of Gardner's syndrome.","PeriodicalId":19675,"journal":{"name":"Oral surgery, oral medicine, and oral pathology","volume":"47 1","pages":"477-86"},"PeriodicalIF":0.0,"publicationDate":"1980-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79059960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1980-04-01DOI: 10.1097/00006534-198004000-00108
R. D. Baker, E. D'Onofrio, R. Corio, B. Crawford, B. Terry
A rare case of well-differentiated squamous-cell carcinoma arising in the epithelial lining of a lateral periodontal cyst is reported. Submission of surgically removed tissues for histopathologic evaluation is emphasized. The surgical site has been reconstructed and functions well. Because of early diagnosis and treatment, the patient has no evidence of clinical disease 2 1/2 years postoperatively.
{"title":"Squamous-cell carcinoma arising in a lateral periodontal cyst.","authors":"R. D. Baker, E. D'Onofrio, R. Corio, B. Crawford, B. Terry","doi":"10.1097/00006534-198004000-00108","DOIUrl":"https://doi.org/10.1097/00006534-198004000-00108","url":null,"abstract":"A rare case of well-differentiated squamous-cell carcinoma arising in the epithelial lining of a lateral periodontal cyst is reported. Submission of surgically removed tissues for histopathologic evaluation is emphasized. The surgical site has been reconstructed and functions well. Because of early diagnosis and treatment, the patient has no evidence of clinical disease 2 1/2 years postoperatively.","PeriodicalId":19675,"journal":{"name":"Oral surgery, oral medicine, and oral pathology","volume":"21 1","pages":"495-9"},"PeriodicalIF":0.0,"publicationDate":"1980-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73986184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1980-02-01DOI: 10.1097/00006534-198202000-00055
G. Manstein, A. Buchner, Hansen. L. S
A series of 268 cases of amalgam tattoo is analyzed both clinically and histologically. The most common location was the gingiva and alveolar mucosa, followed by the buccal mucosa. Histologically, the amalgam was present in the tissues as discrete, fine, dark granules and as irregular solid fragments. The dark granules were arranged mainly along collagen bundles and around blood vessels. They were also associated with the walls of blood vessels, nerve sheaths, elastic fibers, basement membranes of mucosal epithelium, striated muscle fibers, and acini of minor salivary glands. Dark granules were also present intracellularly within macrophages, multinucleated giant cells, endothelial cells, and fibroblasts. Although in 45% of the cases there was no tissue reaction to the amalgam, in 17% there was a macrophagic reaction and in 38% there was a chronic inflammatory response, usually in the form of a foreign body granuloma, with multinucleated giant cells of the foreign body and Langhans types. Asteroid bodies were also found in some of the foreign body giant cells.
{"title":"Amalgam pigmentation (amalgam tattoo) of the oral mucosa. A clinicopathologic study of 268 cases.","authors":"G. Manstein, A. Buchner, Hansen. L. S","doi":"10.1097/00006534-198202000-00055","DOIUrl":"https://doi.org/10.1097/00006534-198202000-00055","url":null,"abstract":"A series of 268 cases of amalgam tattoo is analyzed both clinically and histologically. The most common location was the gingiva and alveolar mucosa, followed by the buccal mucosa. Histologically, the amalgam was present in the tissues as discrete, fine, dark granules and as irregular solid fragments. The dark granules were arranged mainly along collagen bundles and around blood vessels. They were also associated with the walls of blood vessels, nerve sheaths, elastic fibers, basement membranes of mucosal epithelium, striated muscle fibers, and acini of minor salivary glands. Dark granules were also present intracellularly within macrophages, multinucleated giant cells, endothelial cells, and fibroblasts. Although in 45% of the cases there was no tissue reaction to the amalgam, in 17% there was a macrophagic reaction and in 38% there was a chronic inflammatory response, usually in the form of a foreign body granuloma, with multinucleated giant cells of the foreign body and Langhans types. Asteroid bodies were also found in some of the foreign body giant cells.","PeriodicalId":19675,"journal":{"name":"Oral surgery, oral medicine, and oral pathology","volume":"105 1","pages":"139-47"},"PeriodicalIF":0.0,"publicationDate":"1980-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80738282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1979-06-01DOI: 10.1097/00132586-197906000-00033
S. Cooper, J. Anthony, E. Mopsik, M. S. Moore, D. Sullivan, G. O. Kruger
The objective of this study was to evaluate the impairment of both psychomotor function and memory after intravenous administration of 17 to 28 mg. of diazepam to normal volunteers. A battery of tests, including word memory, Seguin form board, digit symbol, digit span, block design, and reaction time, was administered at set intervals to both drug and nondrug subjects. The diazepam group demonstrated both psychomotor and anterograde memory deficits which persisted throughout the 150-minute evaluation; but relative to the control group, the diazepam group had enhanced retrograde memory. These preliminary results indicate that even after subjects appear to be recovered from the effect;s of diazepam, residual psychomotor and memory impairment remain.
{"title":"A technique for investigating the intensity and duration of human psychomotor impairment after intravenous diazepam.","authors":"S. Cooper, J. Anthony, E. Mopsik, M. S. Moore, D. Sullivan, G. O. Kruger","doi":"10.1097/00132586-197906000-00033","DOIUrl":"https://doi.org/10.1097/00132586-197906000-00033","url":null,"abstract":"The objective of this study was to evaluate the impairment of both psychomotor function and memory after intravenous administration of 17 to 28 mg. of diazepam to normal volunteers. A battery of tests, including word memory, Seguin form board, digit symbol, digit span, block design, and reaction time, was administered at set intervals to both drug and nondrug subjects. The diazepam group demonstrated both psychomotor and anterograde memory deficits which persisted throughout the 150-minute evaluation; but relative to the control group, the diazepam group had enhanced retrograde memory. These preliminary results indicate that even after subjects appear to be recovered from the effect;s of diazepam, residual psychomotor and memory impairment remain.","PeriodicalId":19675,"journal":{"name":"Oral surgery, oral medicine, and oral pathology","volume":"33 1","pages":"493-502"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81018107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1978-12-01DOI: 10.1097/00006534-197812000-00089
D. White, S. Chen, K. S. Hartman, A. Miller, L. F. Gomez
Four cases of central granular-cell tumor of the jaws were evaluated to determine the clinical parameters of the lesion, and one of these cases was examined with the electron microscope to investigate the nature of the granular cells. The average age of the patients at the time of treatment was 55 years; all four patients were women. Three of the lesions originated in the mandible, and one in the maxilla. Follow-up studies revealed no recurrences. Electron microscopic examination of one case revealed that the granular cells contained many lysosome-like particles and that these cells are identical to those found in the granular-cell myoblastoma.
{"title":"Central granular-cell tumor of the jaws (the so-call granular-cell ameloblastic fibroma).","authors":"D. White, S. Chen, K. S. Hartman, A. Miller, L. F. Gomez","doi":"10.1097/00006534-197812000-00089","DOIUrl":"https://doi.org/10.1097/00006534-197812000-00089","url":null,"abstract":"Four cases of central granular-cell tumor of the jaws were evaluated to determine the clinical parameters of the lesion, and one of these cases was examined with the electron microscope to investigate the nature of the granular cells. The average age of the patients at the time of treatment was 55 years; all four patients were women. Three of the lesions originated in the mandible, and one in the maxilla. Follow-up studies revealed no recurrences. Electron microscopic examination of one case revealed that the granular cells contained many lysosome-like particles and that these cells are identical to those found in the granular-cell myoblastoma.","PeriodicalId":19675,"journal":{"name":"Oral surgery, oral medicine, and oral pathology","volume":"10 1","pages":"396-405"},"PeriodicalIF":0.0,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88521108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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