OTO Open最新文献

Objective: This umbrella review aims to evaluate the clinical outcomes of robotic-assisted thyroid surgery compared to traditional endoscopic and open surgical approaches.

Data sources: We conducted a systematic search of PubMed, EMBASE, and Cochrane Database through August 2024.

Review methods: We conducted a comprehensive analysis of systematic reviews and meta-analyses that compare robotic-assisted thyroid surgery with endoscopic or open methods. The primary outcomes assessed include surgical efficiency indicators, general postoperative complications, specific complications (nerve and endocrine), postoperative recovery and patient experience, and recurrence and long-term prognosis. The methodological quality of the included reviews was assessed using the AMSTAR2 tool.

Results: Of the 1987 articles retrieved, 21 were eligible. Robotic surgery, though associated with longer operative times, offers distinct advantages in terms of precision. Although robotic surgery shows some variation in central lymph node dissection and an increase in postoperative drainage, its safety is comparable to both open and endoscopic techniques. Additionally, robotic surgery demonstrates superior cosmetic outcomes and shorter hospital stays from multiple approaches, though its high costs remain a significant factor. In terms of recurrence and survival rates, no significant differences were observed between robotic and open surgery.

Conclusion: Robotic surgery choices should balance benefits, costs, and patient needs. As technology and skills improve, efficiency and cost-effectiveness may increase, expanding its clinical role.

Objective: Macroglossia is a risk factor for obstructive sleep apnea (OSA) and has been linked to an elevated apnea-hypopnea index (AHI). Obesity may contribute to macroglossia, but its exact relationship is unknown and likely multifactorial, and the degree to which increased adiposity of the tongue affects the development of OSA is not understood. The primary objective of this study was to evaluate how tongue fat and volume relate to the presence and severity of OSA.

Data sources: Studies reporting the impact of tongue fat or volume were identified using predefined inclusion criteria from September 2002 to 2022.

Review methods: All studies underwent a 2-stage blinded screening, extraction, and evaluation process. Primary outcomes were the effect of tongue fat and volume on OSA severity and evaluation of study quality. Secondary outcomes included the impact of obesity on tongue fat distribution and OSA severity.

Results: Out of 930 studies, 6 studies with 219 patients and 133 controls were included in meta-analysis. All 6 studies were case-control designs. Included studies showed low (4) and moderate (2) risks of bias. All studies compared tongue volume with an observed significant increase in tongue volume in OSA patients (P < .00001) with a weighted mean difference of 19.00 cm³ [15.53, 22.47]. Two studies compared tongue fat, and there was a significant increase in tongue fat in patients with OSA (P < .00001) with a weighted mean difference of 8.04 cm³ [4.25, 11.82].

Conclusion: This meta-analysis supports increased tongue volume and tongue adipose as important risk factors associated with OSA. Larger studies investigating tongue fat distribution and the effect of weight changes on tongue fat and volume and OSA severity are needed to characterize this relationship better.

Objective: To better understand the prevalence, risk factors, and management strategies of pregnancy-related rhinologic conditions.

Study design: Retrospective cohort study from January 2013 to January 2023.

Setting: Tertiary level Otolaryngology-Head and Neck Surgery clinic.

Methods: Pregnant patients with rhinologic concerns were included. Data were collected on various parameters including age during pregnancy, gestational age at evaluation for rhinologic complication, obstetric history, history of pregnancy loss, primigravida status, rhinologic condition, aspirin usage during pregnancy, and presence of advanced maternal age (AMA, ≥35 years old). Stata/SE 17.0 Software was used for statistical analysis. A P-value of <.05 was considered significant.

Results: Fifty-seven pregnant patients were included. Patients presented with epistaxis (N = 25, 43.9%), chronic rhinosinusitis exacerbations (N = 22, 38.6%), and rhinitis of pregnancy (N = 10, 17.5%). Mean age at presentation was 34.7 years (22-53). Multivariate analysis revealed associations between epistaxis and primigravida status (P = .008) and rhinitis of pregnancy with a history of pregnancy loss (P = .012). Gestational diabetes mellitus was significantly associated with epistaxis on univariate analysis (P = .011).

Conclusion: There is a need for increased awareness among health care providers, including otolaryngologists, regarding the diagnosis and management of rhinologic conditions of pregnancy.

Objective: With more than 1.57 billion people affected by hearing loss worldwide, this study investigates the association between ototoxic drug use and hearing loss, utilizing South Korean national health data. The goal is to inform clinical prevention and management guidelines by identifying ototoxic drugs and assessing their risks.

Study design: This study is a retrospective observational study using the Health Insurance Review and Assessment Service (HIRA) to analyze the association between suspected ototoxic drug use and hearing loss.

Setting: Data were obtained from the National Patient Samples (NPS) of HIRA in South Korea, covering 2009 to 2016. The study included all National Health Insurance (NHI) enrollees with at least one hospital visit.

Methods: Patients diagnosed with suspected ototoxicity hearing loss (SOHL) were identified, and ototoxic drugs were reviewed using national data. Of 491 reviewed ingredients, 151 were suspected ototoxic. Logistic regression and Cox proportional hazards models assessed associations between drug prescriptions and SOHL, analyzed with SAS 9.4.

Results: SOHL patients were older, with higher rates of underlying conditions and medication use compared to controls. The odds ratio (OR) for SOHL was significantly elevated in patients aged ≥65, increasing from 3.007 to 3.366. Proton pump inhibitors (PPIs) and antibiotics presented elevated risks, especially in older adults, with hazard ratios (HRs) for PPIs rising from 1.85 to 2.90. Notably, PPIs posed higher risks for patients <65.

Conclusion: The study confirms that factors like age, gender, underlying diseases, and specific medications increase SOHL risk, emphasizing the need for cautious medication use tailored to age.

Objective: Sialendoscopy is a diagnostic and interventional treatment for patients with salivary disease. Patients and physicians leverage website information to acquire knowledge about sialendoscopy; thus, understanding the quality of this information is essential. This study analyzes the quality and readability of online information on sialendoscopy.

Methods: "Sialendoscopy" was searched on Google, and the first 100 websites were evaluated. Each website was required to meet three criteria for inclusion: accessible when opened, content deemed relevant, and available in written format. Four validated readability and two validated reliability metrics were utilized. Additionally, a separate analysis was conducted for the top nine websites in the search engine, given most web traffic occurs on Google's first page.

Results: In assessing readability, the mean Flesch Reading Ease Score for included and the top nine websites was 36.2 and 39.5, respectively, with a P-value of .543. Both scores aligned with the "difficult to read" category. Other readability metrics aligned with high school reading levels. For reliability, the mean Discern score for the included and the top nine websites was 36.9 and 45.0, respectively, with a P-value of .030. These scores aligned with the "poor" and "fair" categories, respectively.

Discussion: The low readability and reliability scores implied that the online health information on sialendoscopy is not easily understandable at a reading level appropriate for the general public. Our findings showed that the most readable and highest quality websites were not the highest ranked in our search results. Factors such as search engine algorithms and complex medical terminology used in these informative websites contribute to the lack of readability and relability of online health education.

Implications for practice: As AI evolves, future studies should be conducted to assess its impact on readability and reliability of online health information. There is an opportunity to adjust search engine algorithms, collaborate with communications specialists, and utilize new technologies, such as artificial intelligence chatbots, for the benefit of health seekers.

Objective: To evaluate the perceptions of American Rhinologic Society (ARS) members on the compensation models of academic rhinologists and their impact on clinical practice, teaching, and academic responsibilities.

Study design: Survey study.

Setting: Academic rhinologists across the United States who are members of the ARS.

Methods: A twenty-six-question survey was distributed to 295 ARS members. The survey collected demographic information such as years of experience, geographic location, practice setting, and consultation volume. It also explored various compensation models and their impact on compensation, patient volume, case types, and the ability to support teaching and academic responsibilities.

Results: Out of 295 surveyed ARS members, 107 responded (36%), and 80 academic rhinologists were included in the final sample. Respondents varied in experience and geographic distribution. Most respondents were salaried (69%), while 63% were under relative value units (RVU)-based models, and 25% were under collections-based models. Additionally, 66% reported poor or no support for research and educational activities. Compensation models were found to influence patient volume (28%), procedure choices (14%), and academic duties, with 55% of respondents indicating reduced engagement with students.

Conclusion: Although a plurality of respondents (39%) believed that salaried models are most conducive to balancing academic and clinical responsibilities, survey findings highlight a dissonance. Respondents under collections-based models were more likely to feel adequately supported (64.71%) compared to those under salaried or RVU-based models. This suggests that although many perceive salaried models as ideal for balance, collections-based models may better address financial and structural needs, emphasizing the importance of developing flexible, tailored compensation structures that align with individual and institutional goals while fostering academic productivity.

Circulating tumor DNA (ctDNA) has been developed as a marker of tumor burden in human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC). Inflammatory indices are also increasingly being used as prognostic surrogate markers in solid tumors, including head and neck cancers. The relationship between ctDNA levels and inflammatory indices has not been studied in HPV-associated OPSCC. We hypothesize that higher levels of inflammation are associated with higher ctDNA levels. Herein, we demonstrate an association between high pretreatment ctDNA levels and specific inflammatory indices, which may be lower-cost surrogate markers of high HPV ctDNA levels and may act as a surrogate marker for the body's immune response to HPV-positive OPSCC.

Objective: This study aims to report the prevalence and characteristics of underrepresented in medicine (URiM) funding for visiting medical student clerkships in Otolaryngology-Head and Neck Surgery (OHNS) residency programs in the United States.

Study design: Manual online review of Accreditation Council for Graduate Medical Education (ACGME)-accredited OHNS residency programs as of January 2024, reflective of typical medical student search methodology.

Setting: An online review.

Methods: For each program, at least 2 authors captured presence of funding, the funding amount, funding origin, and eligibility criteria. Presence and amount funding were analyzed for possible associations with program type (by FREIDA™ program description), urbanization level, cost of living, and degree of racial and ethnic diversity in the program's geographic location.

Results: Of 131 programs, 49 (37.4%) offered URiM funding, primarily through diversity, equity, and inclusion (DEI) entities (67.3%) or OHNS departments (32.7%). Mean funding per 1-month rotation was $1908. Eligibility criteria varied, with 63.2% using a non-specific URiM definition and 18.4% following the Association of American Medical Colleges definition. Funding presence did not differ by geographic region (P = .06), program type, urbanization level, or cost of living. However, funding amounts varied significantly by region (P < .01) and were significantly different between programs in diversity index 35.0% to 44.9% versus 45.0% to 54.9% and 55.0% to 64.9% (P = .007 and P = .002, respectively).

Conclusion: URiM funding is available in a minority of OHNS programs, with substantial variability in funding amount and eligibility criteria. Standardized guidance on defining URiM eligibility may benefit students and institutions. Funding may correlate with local racial and ethnic diversity, warranting further research.