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[The effect of asbestos cement, UICC asbestos samples and quartz on the peritoneum of the mouse]. [石棉水泥、UICC石棉样品和石英对小鼠腹膜的影响]。
Pub Date : 1975-01-01 DOI: 10.1159/000162717
T. Wirth
Aqueous suspensions of asbestos cement powder injected experimentally into the peritoneal cavity of mice act as a fibrogenic agent, as do chrysotile asbestos or chrysotile asbestos-containing soil samples. The fibrotic nodules caused by the dust resemble morphologically silicosis granulomas. In addition, asbestos cement has a characteristically strong cytotoxic effect during the first 2 weeks of the experiment. It is suggested that this is due to the chrysotile asbestos and/or the calcite component of the powder. Amosite and crocidolite, on the other hand, induce a diffuse peritoneal fibrosis with the appearance of numerous foreign body giant cells and asbestos bodies. Dust particles displaced to the regional lymph nodes are frequent in the animals treated with quartz, asbestos cement and asbestos-containing soil samples. A spindle cell type sarcoma arising from the visceral peritoneum is observed in animals injected with crocidolite or asbestos cement. In addition, dusts containing chrysotile asbestos induce considerable amyloidosis of the liver and spleen.
石棉水泥粉的水悬浮液被实验性地注射到小鼠的腹膜腔中,就像温石棉或含温石棉的土壤样品一样,起着纤维原性的作用。粉尘引起的纤维化结节在形态上类似矽肺肉芽肿。此外,石棉水泥在实验的前两周具有特征性的强细胞毒作用。有人认为,这是由于温石棉和/或方解石成分的粉末。另一方面,阿莫石和石棉石可诱发弥漫性腹膜纤维化,伴有大量异物巨细胞和石棉小体的出现。在用石英、石棉水泥和含石棉土壤样本处理的动物中,经常出现转移到局部淋巴结的粉尘颗粒。在注射了鳄鱼石或石棉水泥的动物中,观察到内脏腹膜出现梭形细胞型肉瘤。此外,含有温石棉的粉尘可引起肝脏和脾脏淀粉样变。
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引用次数: 5
Proceedings: Epidemiological remarks. Discussion. 会议录:流行病学评论。讨论。
Pub Date : 1975-01-01
F H Epstein
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引用次数: 0
African human trypanosomal pancarditis involving the conduting system and all valves. 非洲人锥虫性胰脏炎,涉及导管系统和所有瓣膜。
Pub Date : 1975-01-01 DOI: 10.1159/000162804
A A Poltera, J N Cox, R Owor
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引用次数: 1
Nonspecific aortitis (Takayasu's disease). Autopsy study of 35 cases. 非特异性主动脉炎(高松病)。35例尸检分析。
Pub Date : 1975-01-01
S G Kinare
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引用次数: 0
Systemic vascular changes of rheumatoid arthritis in Japan. 日本类风湿关节炎的全身血管改变。
Pub Date : 1975-01-01
M Kyogoku
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引用次数: 0
Introductory lecture (Askanazy lecture). Some remarks on the history of arterial pathology. 导论讲座(Askanazy讲座)。关于动脉病理史的一些评论。
Pub Date : 1975-01-01 DOI: 10.1159/000162797
H M Koelbing
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引用次数: 5
An outbreak of acute hemorrhagic conjunctivitis in Yugoslavia in 1973. 1973年南斯拉夫爆发急性出血性结膜炎。
Pub Date : 1975-01-01 DOI: 10.1159/000162718
M Likar, L Talanyi-Pfeifer, J Marin

An outbreak of approximately 200 cases of acute hemorrhagic conjunctivitis is described in Prekmurje, a northern province in Yugoslavia. The epidemic was caused by enterovirus type 70, serologically identical with the causative agents of similar outbreaks in London and Japan. The origin of the outbreak could not be elucidated but a link was seen between this case and a small outbreak in Veenendaal in the Netherlands.

在南斯拉夫北部省份普雷克穆列爆发了大约200例急性出血性结膜炎。该流行病是由肠道病毒70型引起的,在血清学上与伦敦和日本类似疫情的病原体相同。暴发的起源无法阐明,但发现该病例与荷兰Veenendaal的一次小规模暴发之间存在联系。
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引用次数: 7
Fowl plague virus adapted to human leukemia cells: interaction with normal human leukocytes and plastic surfaces. 适应人类白血病细胞的禽鼠疫病毒:与正常人类白细胞和塑料表面的相互作用。
Pub Date : 1975-01-01 DOI: 10.1159/000162794
A Borek, C Sauter

An avian influenza A virus which grows well in human leukemic myeloblasts was unable to replicate in normal human leukocytes. The virus adhered during the first hours of incubation to plastic surfaces and to leukocytes and was then released into the supernatant; care should be taken not to confuse this with viral growth.

一种在人白血病母细胞中生长良好的甲型禽流感病毒不能在正常人白细胞中复制。在孵育的最初几个小时内,病毒粘附在塑料表面和白细胞上,然后被释放到上清中;要注意不要将其与病毒生长相混淆。
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引用次数: 0
Submicroscopic response of articular chondrocytes to a cholesterol-containing diet. 关节软骨细胞对含胆固醇饮食的亚显微反应。
Pub Date : 1975-01-01 DOI: 10.1159/000162840
R Silberberg, M Hasler

10 days' to 3 months' consumption of a diet containing 4% cholesterol causes a minor and transitory stimulation of articular chondrocytes of mice. The transitory disturbance is accompanied by a more permanent increase in glycogen, by abnormal deposition of cytoplasmic lipid and by an increase in the fibrillarity of the pericellular matrix. The changes are consistent with the failure of the cholesterol diet to influence the course of osteoarthrosis if fed to mice from an early age through life.

在10天至3个月的时间里,摄入含有4%胆固醇的饮食会对小鼠的关节软骨细胞产生轻微和短暂的刺激。暂时性的紊乱伴随着更持久的糖原增加、细胞质脂质异常沉积和细胞周围基质纤维性增加。这些变化与从幼年一直喂给小鼠的胆固醇饮食无法影响骨关节病的过程是一致的。
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引用次数: 2
F antigen. II. Chemical and physical properties. F抗原。2化学和物理性质。
Pub Date : 1975-01-01
R Utzinger

Physical and chemical properties of the liver-specific F antigen suggested a model for the labile quarternary structure of the protein. The native molecule showed a size slightly larger than 60,000 dalton (d), which was reduced to about 40,000 d under acidic conditions. Breaking of hydrogen bonds by chaotropic treatment resulted in the release of components of 30,000, 7,000 and 2,000 d. The smallest component was split to fragments of about 1,000 d by the reducing action of sulfhydryl compounds.

肝脏特异性F抗原的物理和化学性质为该蛋白的不稳定的四级结构提供了一个模型。天然分子的尺寸略大于60,000道尔顿(d),在酸性条件下减小到40,000 d左右。朝乱性处理导致氢键断裂,释放30,000、7,000和2,000 d的组分。最小的组分在巯基化合物的还原作用下被分裂成约1,000 d的片段。
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引用次数: 0
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