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Thai parents' perspectives on understanding and involvement in non-pharmacological neonatal pain management. 泰国父母对理解和参与非药物新生儿疼痛管理的观点。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2026-01-14 DOI: 10.1016/j.pmn.2025.12.012
Onanong Mala, Siriporn Vetcho, Victoria J Kain, Elizabeth Forster, Thankornnan Nalathan, Kassarin Maneesing, Pinsuda Sangkano

Background: While neonatal care units (NCUs) are essential for critical neonatal care, they expose neonates to frequent painful procedures. Despite the benefits of non-pharmacological pain management and family-centered care (FCC), Thai parents' perspectives in alleviating their infants' pain remain under-reported.

Aim: To explore Thai parents' perspectives regarding their understanding of and involvement in non-pharmacological pain management strategies.

Methods: A qualitative descriptive study was conducted using face-to-face, semi-structured interviews with 12 parents of neonates admitted to two units of university hospital in Southern Thailand between March and April 2025. Data were analyzed using inductive thematic analysis.

Results: Five major themes emerged: 1) Parents' recognition and interpretation of their baby's pain; 2) Parental coping strategies and involvement in pain alleviation; 3) Gaps in communication and information from healthcare professionals; 4) Preferences for information delivery and suggestions for improvement; and 5) Cultural and religious considerations.

Conclusions: Thai parents demonstrate strong willingness to support their infants' pain relief but face structural, cultural, and informational barriers. Improved communication, culturally sensitive education, and inclusive visitation policies could enhance FCC and empower parents in neonatal pain management.

Clinical implications: Standardized communication and culturally tailored education, including materials both Thai and "Ja-Wi", can better equip parents to support neonatal pain management. Revising visitation policies and enhancing staff training can also promote parental involvement and strengthen FCC in Thai NCUs.

背景:虽然新生儿护理单位(ncu)是至关重要的新生儿护理,他们暴露了新生儿频繁的痛苦过程。尽管非药物疼痛管理和以家庭为中心的护理(FCC)有好处,但泰国父母在减轻婴儿疼痛方面的观点仍未得到充分报道。目的:探讨泰国父母对非药物疼痛管理策略的理解和参与。方法:采用面对面、半结构化访谈的方法对泰国南部大学医院于2025年3月至4月间收治的12名新生儿父母进行定性描述性研究。数据分析采用归纳专题分析。结果:主要有五大主题:1)父母对婴儿疼痛的认知与解读;2)父母应对策略与疼痛缓解参与;3)医疗保健专业人员的沟通和信息差距;4)信息传递的偏好和改进建议;5)文化和宗教方面的考虑。结论:泰国父母表现出强烈的意愿支持他们的婴儿疼痛缓解,但面临结构,文化和信息障碍。改善沟通、文化敏感教育和包容性探视政策可以加强FCC,并赋予父母新生儿疼痛管理的权力。临床意义:标准化沟通和文化定制教育,包括泰语和“Ja-Wi”材料,可以更好地装备父母支持新生儿疼痛管理。修订探视政策和加强员工培训也可以促进家长的参与,并加强泰国非公立学校的FCC。
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引用次数: 0
Validation of the Barriers and Facilitators of Chronic Cancer Pain Self-Management Instrument. 慢性癌症疼痛自我管理工具的障碍和促进因素的验证。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2026-01-14 DOI: 10.1016/j.pmn.2025.11.010
Batool Almasri, Deborah McDonald, Rawan AlAssaf

Purpose: Cancer pain significantly affects patients' quality of life, yet facilitators and barriers to patient pain self-management remain poorly understood. This study aimed to quantitatively validate and test the Barriers and Facilitators of Chronic Cancer Pain Self-Management (BFCCPSM) instrument, which identifies barriers and facilitators of chronic pain self-management among people with cancer using Creswell and Clark typology.

Design: Through a quantitative approach, this study evaluated the BFCCPSM instrument, the first tool to assess both facilitators and barriers facing patients in home settings.

Methods: The study sample comprised 200 patients who were recruited using online platforms and from an oncology center. Nine factors (51 items) were identified through principal component analysis and showed acceptable construct validity and internal consistency (65.8% of the variance explained and Cronbach's α = 0.70-0.88, respectively). The tool was composed of two main constructs: barriers (patient-health care provider relationship, fear of side effects, addiction concerns, negative beliefs, psychological stressors, discrimination, transportation) and facilitators (family, friends, and social support and self-efficacy and active role).

Results: Significant differences were observed between groups (i.e., age, marital status, and race), which supported the criterion validity of the instrument. Noteworthy is that transportation and discrimination were reported as novel barriers, whereas social support and self-efficacy were the main facilitators.

Conclusions: Despite the study limitations represented by the length of the survey and the included sample size, the BFCCPSM contributes to filling a gap in the field, as it addresses factors previously unmet in the self-management of chronic cancer pain, providing a basis for person-centered interventions and health equity. Future studies should validate the instrument with other populations and refine its factors.

Clinical implications: Identifying barriers and facilitators to chronic cancer pain self-management can inform targeted strategies to improve health equity and reduce bias in care. Use of the BFCCPSM instrument within quality improvement initiatives may support organizational and provider-level interventions, including addressing transportation barriers and enhancing key facilitators such as social support and self-efficacy, across patient, provider, and health system levels.

目的:癌症疼痛显著影响患者的生活质量,但患者疼痛自我管理的促进因素和障碍仍然知之甚少。本研究旨在定量验证和测试慢性癌症疼痛自我管理的障碍和促进因素(BFCCPSM)工具,该工具使用Creswell和Clark类型识别癌症患者慢性疼痛自我管理的障碍和促进因素。设计:通过定量方法,本研究评估了BFCCPSM仪器,这是第一个评估家庭环境中患者面临的促进因素和障碍的工具。方法:研究样本包括200名通过在线平台和肿瘤中心招募的患者。主成分分析共鉴定出9个因子(51个项目),结构效度和内部一致性均可接受(65.8%的方差得到解释,Cronbach’s α = 0.70 ~ 0.88)。该工具由两个主要构念组成:障碍(患者-医疗保健提供者关系、对副作用的恐惧、成瘾担忧、消极信念、心理压力源、歧视、交通)和促进因素(家庭、朋友、社会支持、自我效能和积极作用)。结果:各组(即年龄、婚姻状况和种族)之间观察到显著差异,支持该工具的标准效度。值得注意的是,交通和歧视被认为是新的障碍,而社会支持和自我效能感是主要的促进因素。结论:尽管研究的局限性体现在调查的长度和纳入的样本量,但BFCCPSM有助于填补该领域的空白,因为它解决了以前在慢性癌症疼痛自我管理中未满足的因素,为以人为本的干预和健康公平提供了基础。未来的研究应在其他人群中验证该工具,并完善其因素。临床意义:确定慢性癌症疼痛自我管理的障碍和促进因素可以为有针对性的策略提供信息,以改善健康公平和减少护理中的偏见。在质量改进计划中使用BFCCPSM工具可以支持组织和提供者层面的干预措施,包括解决运输障碍和增强关键的促进因素,如患者、提供者和卫生系统层面的社会支持和自我效能。
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引用次数: 0
Hospice Nurses' Views About the Necessity for Palliative Sedation in Existential Suffering. 临终关怀护士对存在性痛苦中姑息镇静必要性的看法。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2026-01-06 DOI: 10.1016/j.pmn.2025.12.001
Dana Hagmann, Susanne Fleckinger, Piret Paal

Purpose: Disagreements between nurses and doctors regarding the assessment and management of existential suffering in terminally ill patients represent a critical challenge in palliative care, particularly in the context of inpatient adult hospices. This study aimed to explore nurses' decision-making processes for palliative sedation in cases of existential suffering in an inpatient adult hospice, providing a comparison with physicians' approaches.

Design: The study employed Charmaz's constructing grounded theory methodology.

Methods: Case-based guided interviews, incorporating a case vignette, were conducted with nurses in a German inpatient adult hospice. Data were analyzed using MAXQDA 22.8.0 following Charmaz's methodology.

Results: Five categories were identified: (1) enabling quality of life until death, (2) perceiving existential suffering, (3) making a decision, (4) performing palliative sedation, and (5) palliative sedation as a solution for existential suffering. In this article, we focus on the decision-making process.

Conclusions: The study highlights the limited involvement of nurses in decision-making processes regarding palliative sedation despite their critical insights into patients' existential suffering. The findings emphasize the need for interdisciplinary collaboration and the integration of nurses' perspectives to achieve more holistic and ethically sound care in inpatient hospices.

Clinical implications: The study emphasizes the need to strengthen nurses' role in palliative sedation to foster ethical practice and reduce moral distress. © 20XX by the American Society for Pain Management Nursing.

目的:护士和医生之间关于临终病人生存痛苦的评估和管理的分歧是姑息治疗的一个关键挑战,特别是在住院成人临终关怀的背景下。本研究旨在探讨在住院成人安宁疗护病患中,护士对于安宁疗护镇静的决策过程,并与医师的做法进行比较。设计:本研究采用Charmaz的建构扎根理论方法论。方法:以个案为基础的引导访谈,结合个案小品,与德国住院成人安宁疗护的护士进行。数据分析采用MAXQDA 22.8.0,采用Charmaz的方法。结果:确定了五个类别:(1)使生活质量直到死亡,(2)感知存在的痛苦,(3)做出决定,(4)实施姑息性镇静,(5)姑息性镇静作为存在性痛苦的解决方案。在本文中,我们关注决策过程。结论:该研究强调了护士在姑息性镇静决策过程中的有限参与,尽管他们对患者存在的痛苦有重要的见解。研究结果强调需要跨学科合作和整合护士的观点,以实现住院病人临终关怀更全面和道德健全的护理。临床意义:该研究强调需要加强护士在姑息性镇静中的作用,以促进道德实践和减少道德困扰。©20XX由美国疼痛管理护理学会出版。
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引用次数: 0
Validation of a Swahili Pediatric Pain Scale in Tanzania: An Observational Study. 斯瓦希里语儿童疼痛量表在坦桑尼亚的验证:一项观察性研究。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2026-01-02 DOI: 10.1016/j.pmn.2025.12.003
Stephen Rineer, Patrick T McGann, Chausiku Paschal, Emmanuela E Ambrose, Luke Smart

Purpose: Limited data are available on the validation or use of culturally and language-specific pediatric self-report pain scales in Sub-Saharan Africa despite the high burden of pain affecting children.

Design: An observational study was conducted to determine the discriminant and convergent validity of two self-report pain scales in Tanzania translated into Swahili: Faces Pain Scale-Revised (FPS-R) and Color Analog Scale (CAS).

Methods: Children aged 5-18 years in the outpatient clinic and inpatient wards at Bugando Medical Center in Mwanza, Tanzania, were eligible. The FPS-R and CAS were translated into Tanzanian Swahili. Discriminant validity was assessed before, during, and after venipuncture using analysis of variance. Convergent validity between the two scales and between parental and child reports was assessed using Spearman correlation.

Results: A total of 107 children were enrolled (56% male, median age 8 years, interquartile range = 6.5-11). A majority (73%) had sickle cell disease. Serial assessments around venipuncture were completed in 46 children, and 74 child-parent dyads were assessed for pain burden, caregiver correlation, and scale preference. Median scores before, during, and 5 and 30 minutes after venipuncture documented an expected increase and decrease in pain over time (p < .001) in both the FPS-R and CAS. The correlation between FPS-R and CAS was r = 0.972 and p < .001. The correlation between parent and child was r = 0.849 and p < .001. Most caregivers (85%) and children (92%) preferred the FPS-R.

Conclusions: The FPS-R was preferred and the parent pain report correlated with the child report.

Clinical implications: The Tanzanian Swahili FPS-R and CAS are valid pediatric pain assessment tools.

目的:在撒哈拉以南非洲,尽管儿童的疼痛负担很高,但关于文化和语言特异性儿科自我报告疼痛量表的验证或使用的数据有限。设计:进行了一项观察性研究,以确定坦桑尼亚翻译成斯瓦希里语的两种自我报告疼痛量表:面部疼痛量表-修订版(FPS-R)和颜色模拟量表(CAS)的判别效度和收敛效度。方法:选取坦桑尼亚姆万扎布甘多医疗中心门诊和住院病房5-18岁的儿童为研究对象。FPS-R和CAS被翻译成坦桑尼亚斯瓦希里语。采用方差分析对静脉穿刺前、中、后的判别效度进行评估。使用Spearman相关评估两个量表之间以及父母和儿童报告之间的收敛效度。结果:共纳入107名儿童(56%为男性,中位年龄8岁,四分位数间距= 6.5-11)。大多数(73%)患有镰状细胞病。对46名儿童进行静脉穿刺前后的系列评估,并对74名儿童-父母对进行疼痛负担、照顾者相关性和量表偏好评估。在ps - r和CAS中,静脉穿刺前、穿刺中、穿刺后5分钟和30分钟的中位评分显示疼痛随时间的增加和减少(p < 0.001)。ps - r与CAS的相关性为r = 0.972, p < 0.001。父母与子女的相关r = 0.849, p < 0.001。大多数看护者(85%)和儿童(92%)更喜欢FPS-R。结论:首选FPS-R,父母报告的疼痛与孩子报告的疼痛相关。临床意义:坦桑尼亚斯瓦希里语FPS-R和CAS是有效的儿科疼痛评估工具。
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引用次数: 0
Contemporary Pain Neuroscience Knowledge and Attitudes Among Students: A Cross-Sectional Study. 当代学生疼痛神经科学知识与态度:一项横断面研究。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2026-01-02 DOI: 10.1016/j.pmn.2025.11.023
Sue E Curfman, William J Best, Molly T Williams, Kathryn Schmidt, Amy Rasmussen, Gary P Austin

Purpose: Healthcare education programs often provide limited training in contemporary pain neuroscience, leaving future professionals ill-prepared to address the pervasive and biopsychosocial problem of chronic pain. Exploration of the level of understanding of contemporary pain neuroscience and the attitudes toward people in pain among university students may help educators identify appropriate roles for students in pain-related interprofessional education. This study assessed and compared knowledge of contemporary pain neuroscience and attitudes and beliefs toward individuals experiencing pain among university students.

Design: Cross-sectional observational study.

Methods: 284 undergraduate and graduate, healthcare and non-healthcare students completed the revised Neurophysiology of Pain Questionnaire and the Health Care Providers' Pain and Impairment Relationship Scale.

Results: Findings revealed a widespread lack of contemporary pain neuroscience knowledge and misinformed attitudes and beliefs about individuals in pain across most groups. Physical Therapy students demonstrated significantly greater contemporary pain neuroscience knowledge and more informed attitudes and beliefs compared to all non-physical therapy healthcare and non-healthcare students. Surprisingly, non-healthcare students displayed comparable contemporary pain neuroscience to healthcare undergraduate and non-physical therapy graduate students, further highlighting gaps in healthcare curricula. Attitudes and beliefs toward individuals in pain were deficient among non-physical therapy healthcare majors and non-healthcare students alike.

Conclusions: These results underscore the need for comprehensive, contemporary pain neuroscience education across healthcare disciplines.

Clinical implications: All universities should consider incorporating contemporary Pain Neuroscience Education into healthcare curricula. Improved knowledge and attitudes among physical therapy students highlight the potential for meaningful contributions to interprofessional pain education through leadership, collaboration, and shared learning.

目的:医疗保健教育项目通常在当代疼痛神经科学方面提供有限的培训,使未来的专业人员在解决慢性疼痛的普遍和生物心理社会问题方面准备不足。探索当代疼痛神经科学的理解水平和大学生对疼痛者的态度可以帮助教育者确定学生在疼痛相关的跨专业教育中的适当角色。本研究评估并比较了当代疼痛神经科学知识和大学生对个体疼痛的态度和信念。设计:横断面观察性研究。方法:284名本科和研究生,医疗保健和非医疗保健学生完成了修订后的疼痛神经生理学问卷和医疗保健提供者疼痛与损害关系量表。结果:研究结果显示,在大多数群体中,普遍缺乏当代疼痛神经科学知识,对个体疼痛的态度和信念存在错误。与所有非物理治疗保健学生和非保健学生相比,物理治疗学生表现出更多的当代疼痛神经科学知识和更多的知情态度和信念。令人惊讶的是,非医疗保健专业的学生在当代疼痛神经科学方面的表现与医疗保健专业的本科生和非物理治疗专业的研究生相当,这进一步突出了医疗保健课程的差距。非物理治疗卫生保健专业学生和非卫生保健专业学生对疼痛个体的态度和信念都存在不足。结论:这些结果强调了在医疗保健学科中开展全面的当代疼痛神经科学教育的必要性。临床意义:所有大学都应考虑将当代疼痛神经科学教育纳入医疗保健课程。物理治疗专业学生的知识和态度的改善突出了通过领导、合作和共享学习为跨专业疼痛教育做出有意义贡献的潜力。
{"title":"Contemporary Pain Neuroscience Knowledge and Attitudes Among Students: A Cross-Sectional Study.","authors":"Sue E Curfman, William J Best, Molly T Williams, Kathryn Schmidt, Amy Rasmussen, Gary P Austin","doi":"10.1016/j.pmn.2025.11.023","DOIUrl":"https://doi.org/10.1016/j.pmn.2025.11.023","url":null,"abstract":"<p><strong>Purpose: </strong>Healthcare education programs often provide limited training in contemporary pain neuroscience, leaving future professionals ill-prepared to address the pervasive and biopsychosocial problem of chronic pain. Exploration of the level of understanding of contemporary pain neuroscience and the attitudes toward people in pain among university students may help educators identify appropriate roles for students in pain-related interprofessional education. This study assessed and compared knowledge of contemporary pain neuroscience and attitudes and beliefs toward individuals experiencing pain among university students.</p><p><strong>Design: </strong>Cross-sectional observational study.</p><p><strong>Methods: </strong>284 undergraduate and graduate, healthcare and non-healthcare students completed the revised Neurophysiology of Pain Questionnaire and the Health Care Providers' Pain and Impairment Relationship Scale.</p><p><strong>Results: </strong>Findings revealed a widespread lack of contemporary pain neuroscience knowledge and misinformed attitudes and beliefs about individuals in pain across most groups. Physical Therapy students demonstrated significantly greater contemporary pain neuroscience knowledge and more informed attitudes and beliefs compared to all non-physical therapy healthcare and non-healthcare students. Surprisingly, non-healthcare students displayed comparable contemporary pain neuroscience to healthcare undergraduate and non-physical therapy graduate students, further highlighting gaps in healthcare curricula. Attitudes and beliefs toward individuals in pain were deficient among non-physical therapy healthcare majors and non-healthcare students alike.</p><p><strong>Conclusions: </strong>These results underscore the need for comprehensive, contemporary pain neuroscience education across healthcare disciplines.</p><p><strong>Clinical implications: </strong>All universities should consider incorporating contemporary Pain Neuroscience Education into healthcare curricula. Improved knowledge and attitudes among physical therapy students highlight the potential for meaningful contributions to interprofessional pain education through leadership, collaboration, and shared learning.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145896522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pupillary Reaction to Opioids on Awake Subjects: A Systematic Review. 清醒受试者对阿片类药物的瞳孔反应:一项系统综述。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2026-01-02 DOI: 10.1016/j.pmn.2025.11.019
Luiza Palmieri Serrano, Sahar Borna, Karla C Maita, Maria Thereza Barbosa, Eduardo S Rodrigues, Sally A Brown, Francisco R Avila, Ricardo A Torres-Guzman, John P Garcia, Clifton R Haider, Antonio Jorge Forte

Objectives: To evaluate the correlation between opioid administration, pupillary changes measured by pupillometry, and patient-reported pain levels in nonprocedural settings, and to assess the utility of pupillometry as an objective tool for pain assessment and opioid efficacy.

Design: Systematic review of published literature.

Data sources: A literature search was conducted in February 2022 using PubMed, CINAHL, Web of Science, and EMBASE to identify studies examining the relationship between opioids, pupillary responses, and pain.

Review/analysis methods: A total of 160 articles were screened, and 14 studies met inclusion criteria for final analysis. Studies were evaluated for associations between opioid administration, pupillary measurements, and pain levels, as well as for reported confounding factors influencing pupillary response.

Results: Most studies demonstrated a significant association between opioid administration and pupillary constriction or altered pupillary reflexes. Several studies also identified correlations between pupillary responses and reported pain levels. Age, intraoperative medications, and individual physiological variability were found to influence pupillary measurements and may act as confounders.

Conclusions: Pupillometry shows promise as an objective indicator of opioid effect and pain response, particularly in settings where subjective pain reporting may be limited or unreliable. However, its interpretation must account for patient-specific and clinical confounding factors.

Nursing practice implications: Pupillary measurement may serve as a useful adjunct to traditional pain assessment tools in outpatient and postoperative settings. Incorporating pupillometry alongside routine vital signs-such as blood pressure, respiratory rate, and temperature-may enhance pain evaluation and support safer opioid prescribing and monitoring practices. Further research is needed to guide clinical implementation and establish standardized protocols.

目的:评估阿片类药物给药、瞳孔测量法测量的瞳孔变化和患者报告的非程序性疼痛水平之间的相关性,并评估瞳孔测量法作为疼痛评估和阿片类药物疗效的客观工具的效用。设计:系统回顾已发表的文献。数据来源:于2022年2月使用PubMed、CINAHL、Web of Science和EMBASE进行文献检索,以确定检查阿片类药物、瞳孔反应和疼痛之间关系的研究。回顾/分析方法:共筛选160篇文献,其中14篇符合最终分析的纳入标准。研究评估了阿片类药物给药、瞳孔测量和疼痛水平之间的关系,以及报道的影响瞳孔反应的混杂因素。结果:大多数研究表明阿片类药物与瞳孔收缩或瞳孔反射改变之间存在显著关联。几项研究也确定了瞳孔反应和报告的疼痛程度之间的相关性。发现年龄、术中用药和个体生理变异会影响瞳孔测量,并可能成为混杂因素。结论:瞳孔测量显示有希望作为阿片类药物效应和疼痛反应的客观指标,特别是在主观疼痛报告可能有限或不可靠的情况下。然而,其解释必须考虑到患者特异性和临床混杂因素。护理实践意义:瞳孔测量可以作为一个有用的辅助,传统的疼痛评估工具,在门诊和术后设置。将瞳孔测量与常规生命体征(如血压、呼吸频率和体温)结合起来,可以加强疼痛评估,并支持更安全的阿片类药物处方和监测实践。需要进一步的研究来指导临床实施和建立标准化的方案。
{"title":"Pupillary Reaction to Opioids on Awake Subjects: A Systematic Review.","authors":"Luiza Palmieri Serrano, Sahar Borna, Karla C Maita, Maria Thereza Barbosa, Eduardo S Rodrigues, Sally A Brown, Francisco R Avila, Ricardo A Torres-Guzman, John P Garcia, Clifton R Haider, Antonio Jorge Forte","doi":"10.1016/j.pmn.2025.11.019","DOIUrl":"https://doi.org/10.1016/j.pmn.2025.11.019","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the correlation between opioid administration, pupillary changes measured by pupillometry, and patient-reported pain levels in nonprocedural settings, and to assess the utility of pupillometry as an objective tool for pain assessment and opioid efficacy.</p><p><strong>Design: </strong>Systematic review of published literature.</p><p><strong>Data sources: </strong>A literature search was conducted in February 2022 using PubMed, CINAHL, Web of Science, and EMBASE to identify studies examining the relationship between opioids, pupillary responses, and pain.</p><p><strong>Review/analysis methods: </strong>A total of 160 articles were screened, and 14 studies met inclusion criteria for final analysis. Studies were evaluated for associations between opioid administration, pupillary measurements, and pain levels, as well as for reported confounding factors influencing pupillary response.</p><p><strong>Results: </strong>Most studies demonstrated a significant association between opioid administration and pupillary constriction or altered pupillary reflexes. Several studies also identified correlations between pupillary responses and reported pain levels. Age, intraoperative medications, and individual physiological variability were found to influence pupillary measurements and may act as confounders.</p><p><strong>Conclusions: </strong>Pupillometry shows promise as an objective indicator of opioid effect and pain response, particularly in settings where subjective pain reporting may be limited or unreliable. However, its interpretation must account for patient-specific and clinical confounding factors.</p><p><strong>Nursing practice implications: </strong>Pupillary measurement may serve as a useful adjunct to traditional pain assessment tools in outpatient and postoperative settings. Incorporating pupillometry alongside routine vital signs-such as blood pressure, respiratory rate, and temperature-may enhance pain evaluation and support safer opioid prescribing and monitoring practices. Further research is needed to guide clinical implementation and establish standardized protocols.</p>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145896527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Centralized Pain Score: A Method to Identify Nociplastic Pain in Electronic Health Records 集中疼痛评分:一种在电子健康记录中识别伤害性疼痛的方法。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2026-01-02 DOI: 10.1016/j.pmn.2025.12.007
Lori Schirle PhD, CRNA, FAAN , Makayla Cordoza PhD, RN, CCRN , Stephen Bruehl PhD , David C. Samuels PhD

Introduction

Chronic overlapping pain conditions (COPCs) are a group of pain conditions that often co-occur and present with challenging nociplastic pain. Individuals with COPCs describe clinician skepticism and prolonged diagnosis, leading to periods of inadequate pain treatment. The lack of methods to identify nociplastic pain in electronic health records (EHRs) limits large-scale studies of nociplastic pain trajectories and phenotyping that could improve treatment.

Objective

To develop and validate the Centralized Pain Score (CPS) as a method for identifying nociplastic pain in EHR data.

Methods

In a large deidentified EHR database, the CPS, which sums central sensitization-weighted COPC ICD codes across individual records, was examined. Descriptive statistics were calculated for three groups: a General Population Group (N = 55,340), a group clinically determined to have nociplastic pain (Nociplastic Pain Group, N = 100), and an Age- and Sex-Matched Group (N = 500). T-tests were used to compare differences in CPS between pairs of these three groups. A post hoc content analysis of clinical documentation was conducted to examine the nomenclature of nociplastic pain.

Results

The Nociplastic Pain Group demonstrated a CPS 8.6-fold higher (mean = 3.7, standard deviation [SD] = 2.9) than the General Population (mean = 0.43, SD = 1.0, p < .001) and 7.9-fold higher than the Age- and Sex-Matched Group (CPS mean = 0.47, SD = 1.1, p < .001). Nociplastic pain was most commonly documented as “central pain syndrome.”

Discussion

Clinicians are documenting nociplastic pain and recommending interventions targeting centralized mechanisms. The CPS appears to capture nociplastic pain. The term central pain syndrome was not intended for nociplastic pain, but it is frequently used.

Conclusion

Using the CPS to examine nociplastic pain could improve early detection of nociplastic pain conditions.
慢性重叠疼痛状况(COPCs)是一组疼痛状况,经常共同发生,并呈现具有挑战性的伤害性疼痛。患有COPCs的个体描述临床医生的怀疑和长时间的诊断,导致疼痛治疗不足的时期。缺乏识别电子健康记录(EHRs)中致伤性疼痛的方法限制了可改善治疗的致伤性疼痛轨迹和表型的大规模研究。目的:开发和验证集中疼痛评分(CPS)作为识别电子病历数据中致伤性疼痛的方法。方法:在一个大型的未确定的电子病历数据库中,对CPS进行了检查,该CPS汇总了各个记录的中心敏化加权COPC ICD代码。对三组进行描述性统计:普通人群组(N = 55,340),临床确定有致伤性疼痛的组(N = 100),年龄和性别匹配组(N = 500)。采用t检验比较三组对间CPS的差异。对临床文献进行事后内容分析,以检查致伤性疼痛的命名法。结果:致痛性疼痛组的CPS比普通人群(平均0.43,SD = 1.0, p < 0.001)高8.6倍(平均3.7,标准差[SD] = 2.9),比年龄和性别匹配组(平均0.47,SD = 1.1, p < 0.001)高7.9倍。伤害性疼痛最常被记录为“中枢性疼痛综合征”。讨论:临床医生正在记录伤害性疼痛并推荐针对集中机制的干预措施。CPS似乎捕捉到了伤害性疼痛。“中枢性疼痛综合征”一词并非指致伤性疼痛,但它经常被使用。结论:应用CPS检查痛性疼痛可提高痛性疼痛的早期发现。
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引用次数: 0
Exploring Biopsychosocial Factors Influencing the Association Between Chronic Pain and Cognitive Impairment. 探讨影响慢性疼痛与认知障碍关系的生物心理社会因素。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-12-27 DOI: 10.1016/j.pmn.2025.12.005
Philemon Domoyeri, Pariya L Fazeli, Prince J Mosley, Edwin N Aroke

Purpose: Chronic pain and cognitive impairment share similar biopsychosocial risk factors; however, little work has directly explored how these factors influence the relationship between chronic pain and cognitive impairment. This review aimed toexamine and integrate available evidence on biopsychosocial factors that influence the relationship between chronic pain and cognitive impairment in adults and develop a framework that will guide future research on this topic.

Design: Integrative review.

Method: Guided by the Whittemore and Knafl (2005) framework, we conducted a search using PubMed, Embase, and CINAHL to identify peer-reviewed, English-language articles published between 2015 and February 2025 with available full text that examined biopsychosocial factors associated with cognitive impairment in adults with chronic pain.

Results: Thirty-one articles were included, revealing four themes: 1) nature and type of chronic pain, 2) biological aging processes, 3) psychological disturbances, and 4) socioenvironmental factors.

Conclusion: Biopsychosocial factors influence the relationship between chronic pain and cognitive impairment through various pathways. Individuals with multifocal chronic pain, which is intense and of long duration, may be at the highest risk for cognitive impairment. Markers of brain aging and epigenetic aging may mediate the relationship between chronic pain and cognitive impairment. Psychological disturbances and the stress response may further mediate cognitive outcomes. Socioenvironmental factors may act as moderators in the relationship such that individuals with low socioeconomic status experience worse cognitive outcomes.

Nursing practice implication: Cognitive assessments should be included in the routine care of individuals with chronic pain.

目的:慢性疼痛和认知障碍具有相似的生物-心理-社会危险因素;然而,很少有研究直接探讨这些因素如何影响慢性疼痛和认知障碍之间的关系。本综述旨在检查和整合影响成人慢性疼痛和认知障碍之间关系的生物心理社会因素的现有证据,并制定一个指导该主题未来研究的框架。设计:综合评价。方法:在Whittemore和Knafl(2005)框架的指导下,我们使用PubMed、Embase和CINAHL进行了检索,以确定2015年至2025年2月之间发表的同行评审的英文文章,并提供全文,这些文章研究了与慢性疼痛成人认知障碍相关的生物心理社会因素。结果:纳入31篇文献,揭示了四个主题:1)慢性疼痛的性质和类型,2)生物衰老过程,3)心理障碍,4)社会环境因素。结论:生物心理社会因素通过多种途径影响慢性疼痛与认知功能障碍的关系。患有多灶性慢性疼痛的个体,其强度和持续时间长,可能处于认知障碍的最高风险。脑老化和表观遗传老化的标志物可能介导慢性疼痛和认知障碍之间的关系。心理障碍和应激反应可能进一步介导认知结果。社会环境因素可能在这种关系中起调节作用,因此社会经济地位低的个体会经历更差的认知结果。护理实践启示:认知评估应纳入慢性疼痛患者的常规护理。
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引用次数: 0
Development of an Opioid Stigma Scale for People Living With Chronic Pain. 慢性疼痛患者阿片类药物耻辱感量表的开发。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-12-27 DOI: 10.1016/j.pmn.2025.12.009
Lisa R Carnago, Mirlene Perry, Brandon A Knettel

Purpose: High levels of stigma among patients with chronic pain contribute to negative psychological well-being. Existing measures have not focused on opioid stigma among individuals with chronic pain who may have legitimate need for opioid therapy.

Design: We developed a measure of opioid stigma that captures two constructs: perceived stigma (awareness of others' negative attitudes) and internalized stigma (application of stereotypes to oneself) among individuals with chronic pain.

Methods: We recruited 180 participants with chronic pain via the online platform CloudResearch to modify an existing stigma scale. We developed items related to perceived stigma (8 items) and internalized stigma (5 items). Concurrent and discriminant validity were evaluated using the Center for Epidemiologic Study Depression Scale-10, Rosenberg Self-Esteem and Brief Resilience Scales. Factor structure were based on Iterated principal factor analysis with Promax rotation.

Results: The final sample included 151 participants, primarily Caucasian (80%), between 30-39 years old (40%), with a history of opioid use (81%). A two-factor solution was identified (MSA = .90), representing perceived and internalized stigma (Eigenvalues 7.23, 2.53; inter-factor correlation = .45, alphas = .94, .94). Semi-partial item correlations ranged from .61-.78 for perceived stigma and .73-.82 for internalized stigma. Significant correlations were observed between perceived stigma and CESD-10 (0.19, p = 0.02), and internalized stigma and resilience (-0.26, p = .001).

Conclusion: The adapted 13-item measure demonstrates sound psychometric properties in evaluating awareness and agreement with stigmatizing attitudes, supporting its reliability and validity.

Clinical implications: Nurses are uniquely positioned to identify opioid stigma, develop interventions, and reduce its impact for individuals with chronic pain.

目的:慢性疼痛患者的高水平耻辱感有助于负面心理健康。现有措施并未关注可能有阿片类药物治疗合理需求的慢性疼痛患者的阿片类药物耻辱感。设计:我们开发了一种测量阿片类药物耻辱感的方法,该方法包含两种结构:慢性疼痛患者的感知耻辱感(对他人负面态度的意识)和内化耻辱感(对自己的刻板印象)。方法:我们通过在线平台CloudResearch招募了180名慢性疼痛患者来修改现有的耻辱感量表。我们开发了与感知耻辱相关的项目(8个)和内化耻辱相关的项目(5个)。采用美国流行病学研究中心抑郁量表-10、罗森博格自尊量表和简易恢复力量表评估量表的并发效度和判别效度。因子结构基于Promax旋转迭代主因子分析。结果:最终样本包括151名参与者,主要是高加索人(80%),年龄在30-39岁之间(40%),有阿片类药物使用史(81%)。鉴定出一个双因素解决方案(MSA = 0.90),代表感知和内化的耻辱感(特征值7.23,2.53;因子间相关= 0.45,alpha = 0.94, 0.94)。项目的半偏相关性在感知到的耻辱感的0.61 - 0.78和内化的耻辱感的0.73 - 0.82之间。感知柱头与csd -10显著相关(0.19,p = 0.02),内化柱头与恢复力显著相关(-0.26,p = 0.001)。结论:经调整的13项量表在评估污名化态度的认知和认同方面具有良好的心理测量特性,支持其信度和效度。临床意义:护士在识别阿片类药物耻辱感,制定干预措施并减少其对慢性疼痛患者的影响方面处于独特的地位。
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引用次数: 0
Looking Past the Single Diagnosis: Resetting Our Perspective on Pain and Multimorbidity 回顾过去的单一诊断:重置我们对疼痛和多病的看法。
IF 2.1 4区 医学 Q2 NURSING Pub Date : 2025-12-26 DOI: 10.1016/j.pmn.2025.12.010
Jeffrey T. Boon Ph.D., R.N., A.G.A.C.N.P.-B.C.
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引用次数: 0
期刊
Pain Management Nursing
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