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Clinical Characteristics and Delayed Diagnosis of Pediatric Patients Presenting to the Emergency Department With a Newly Diagnosed Central Nervous System Tumor: A Single Institutional Experience. 急诊科新确诊中枢神经系统肿瘤儿科患者的临床特征和延迟诊断:单一机构的经验。
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-05-23 DOI: 10.1097/PEC.0000000000003227
Vanessa Tamas, Kathryn Hollenbach, Fareed Saleh, John Crawford, David J Gutglass

Background: Due to the varied symptomatology and inconsistent features on neurologic exam, central nervous system (CNS) tumors are difficult to diagnosis in a timely manner.

Objective: To determine the clinical, neurological, and neuroimaging features of newly diagnosed CNS tumors presenting to the emergency department (ED).

Methods: We evaluated a retrospective cohort of 121 consecutive patients presenting to a tertiary care pediatric ED over 7 consecutive years with newly diagnosed CNS tumors. Clinical symptomatology, neurologic findings reported by emergency room and neurology physicians, neuroimaging features, and time to diagnosis were analyzed.

Results: A total of 116 (48 female, median age 8.0 years (interquartile range, 4.4-12.6), 52% Hispanic) presented to the ED (64% self-referred) diagnosed with a brain tumor (54% posterior fossa, 24% embryonal, 24% low-grade glioma, 16% high-grade glioma) resulting in hospital admission in 92% of cases. Five were diagnosed with extradural spinal, clivus, or orbital apex tumors. Symptomatology or duration did not differ when stratified by demographics, location, or histologic subtype. Moderate degree of concordance was observed among neurologic examinations performed by ED physicians and neurologists. Delayed diagnosis (median delay = 3.5 [1-7] months) was seen in 14% of patients, 13 with primary brain tumors (11 hemispheric, 2 brain stem). Six children with delayed diagnosis of low-grade glial tumors had a nonfocal neurologic examination in comparison to 5 patients with abnormal examinations observed with primary spinal or extradural CNS tumors. Four patients with posterior fossa tumors (3 medulloblastoma, 1 ependymoma) had normal/near normal neurologic examination at presentation despite posterior fossa symptomatology related to increased intracranial pressure.

Conclusions: Our series highlights the complexity of symptomology and neurologic findings in children presenting to the ED with newly diagnosed CNS tumors who may have a normal neurologic examination. Standardization of symptom assessment and focused neurologic examinations may lead to earlier neuroimaging and prevent delayed diagnosis.

背景:由于中枢神经系统(CNS)肿瘤症状多样且神经系统检查特征不一致,因此很难及时诊断:目的:确定急诊科(ED)新诊断的中枢神经系统肿瘤的临床、神经学和神经影像学特征:方法:我们对一家三级医院儿科急诊科连续 7 年收治的 121 名新确诊中枢神经系统肿瘤患者进行了回顾性队列评估。我们对临床症状、急诊室和神经内科医生报告的神经系统检查结果、神经影像学特征以及确诊时间进行了分析:共有 116 名患者(48 名女性,中位年龄为 8.0 岁(四分位数间距为 4.4-12.6),52% 为西班牙裔)因脑肿瘤(54% 为后窝、24% 为胚胎性、24% 为低级别胶质瘤、16% 为高级别胶质瘤)就诊于急诊室(64% 为自我转诊),其中 92% 的病例入院治疗。其中 5 例被诊断为硬膜外脊髓、颅骨或眶顶肿瘤。根据人口统计学、位置或组织学亚型进行分层后,症状或病程并无不同。急诊科医生和神经内科医生进行的神经系统检查具有一定程度的一致性。14%的患者被延迟诊断(中位延迟时间=3.5 [1-7] 个月),其中13例为原发性脑肿瘤(11例为半球型,2例为脑干型)。与原发性脊髓或硬膜外中枢神经系统肿瘤的5名检查异常患者相比,低级别胶质瘤的6名延迟诊断患儿的神经系统检查无病灶。4例后窝肿瘤患者(3例髓母细胞瘤,1例上胚绒毛膜瘤)尽管后窝症状与颅内压增高有关,但在就诊时神经系统检查正常/接近正常:我们的系列研究强调了新诊断为中枢神经系统肿瘤的儿童在就诊急诊时症状和神经系统检查结果的复杂性,而这些儿童的神经系统检查结果可能是正常的。症状评估和重点神经系统检查的标准化可能会导致更早的神经影像学检查,避免延误诊断。
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引用次数: 0
Extracorporeal Cardiopulmonary Resuscitation: CME Review. 体外心肺复苏:CME 回顾。
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-08-01 DOI: 10.1097/01.pec.0001028024.24080.fc
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引用次数: 0
Social Care Education and Training Among US Pediatric Emergency Medicine Fellowship Programs. 美国儿科急诊医学奖学金项目中的社会关怀教育和培训。
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-04-02 DOI: 10.1097/PEC.0000000000003168
Raymen Rammy Assaf, Ryan David Assaf, Hannah Barber Doucet, Danielle Graff

Objective: The aim of the study is to assess the association of social determinants of health (SDOH) education and social needs training on pediatric emergency medicine (PEM) physician perception and practices of social care.

Methods: Data were derived from the 2021 National Social Care Practices Survey of PEM program directors (PDs) and fellows. Ordinal and binary logistic regression modeling were completed for educational/training factors and social care perspective and practice outcomes.

Results: A national sample of 44 PDs (49% response rate) and 109 fellows (28%) participated. A minority of fellows received SDOH education and social needs training during fellowship. Fellows and PDs with SDOH education had a 3.1 odds (95% confidence interval CI, 1.4-6.9) of screening for social needs, with 4.4 odds among fellows (95% CI, 1.2-20.7). Those with social needs training were more comfortable assessing social risk, with 2.4 odds overall (95% CI, 1.2-4.7) and 3.1 odds among fellows (95% CI, 1.4-6.7). They also had 2.4 odds overall (95% CI, 1.1-4.9) of screening for social needs, with a 2.9 odds among fellows (95% CI, 1.3-6.8).

Conclusions: Social care education and training appear to be associated with comfort assessing social risk and social needs screening tendency among both PEM PDs and fellows. Key areas for educational interventions are identified among PEM fellows, who are uniquely positioned as clinical leaders and patient advocates.

研究目的本研究旨在评估健康的社会决定因素(SDOH)教育和社会需求培训与儿科急诊医学(PEM)医生对社会关怀的认知和实践之间的关联:数据来自 2021 年对儿科急诊医学项目主任(PDs)和研究员进行的全国社会关怀实践调查。对教育/培训因素、社会关怀观点和实践结果进行了正态和二元逻辑回归建模:全国共有 44 名项目主任(回复率为 49%)和 109 名研究员(回复率为 28%)参与研究。少数研究员在研究期间接受了 SDOH 教育和社会需求培训。接受过 SDOH 教育的研究员和临床医生筛查社会需求的几率为 3.1(95% 置信区间 CI,1.4-6.9),而研究员的几率为 4.4(95% 置信区间 CI,1.2-20.7)。接受过社会需求培训的人在评估社会风险时更得心应手,总体几率为 2.4(95% 置信区间 CI,1.2-4.7),研究员中的几率为 3.1(95% 置信区间 CI,1.4-6.7)。他们筛查社会需求的总体几率为 2.4(95% CI,1.1-4.9),其中研究员的几率为 2.9(95% CI,1.3-6.8):结论:社会关怀教育和培训似乎与评估社会风险的舒适度以及PEM PD和研究员的社会需求筛查倾向有关。PEM研究员作为临床领导者和患者代言人,具有独特的定位,因此他们是教育干预的关键领域。
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引用次数: 0
Isolated Fallopian Tube Torsion in Children With Hydrosalpinx: Is Conservative Management an Option? 输卵管积水患儿的孤立性输卵管扭转:保守治疗是一种选择吗?
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-05-15 DOI: 10.1097/PEC.0000000000003209
Aurora Mariani, Frédéric Hameury, Rémi Dubois, Delphine Demède, Thomas Gelas, Pierre Yves Mure, Daniela Gorduza

Background: Isolated fallopian tube torsion (IFTT) is very rare gynecological emergency in pediatric population. Our objective is to assess treatment options and discuss outcome of a cohort of IFTT with a focus on the association between IFTT and hydrosalpinx (HSX).

Methods: A retrospective review was conducted. Pediatric patients with IFTT operated in the same center were included.

Results: Seventeen girls (aged: 11-16 years) were managed for acute abdominal pain between 2008 and 2018, with intraoperative diagnosis of IFTT. All patients underwent laparoscopic exploration, with laparoscopically fallopian tube detorsion in all patients. Based on the association of IFTT with HSX after fallopian tube detorsion, patients were divided into 2 groups: group 1 (IFTT without HSX; 12 girls) and group 2 (IFTT with HSX; 5 girls). During the same surgery, complementary surgical procedures were done. In group 1: salpingectomies (4), partial salpingectomies (2) and cystectomies (6) were done. In group 2: salpingectomy (1), salpingotomy (1), and cyst ablation (1). The treatment was called conservative when the tube was preserved.Follow-up was uneventful in group 1. In group 2, for all patients with initial fallopian tube preservation, further surgical procedures were necessary (1-4 surgeries/patient), and, finally, another 3 patients required salpingectomy.

Conclusions: Conservative treatment with tube preservation of IFTT without HSX appeared to be beneficial compared to those with HSX, with no recurrence of torsion or symptoms during the follow-up. However, the same conservative treatment was not sufficiently effective for IFTT with HSX and required further procedures due to recurrence of torsion.

Level of evidence: IV.

背景:孤立性输卵管扭转(IFTT)是儿童中非常罕见的妇科急症。我们的目的是评估治疗方案并讨论一组 IFTT 的结果,重点是 IFTT 与输卵管积水(HSX)之间的关联:方法:进行回顾性研究。方法:进行回顾性研究,纳入在同一中心接受手术的 IFTT 儿科患者:2008年至2018年期间,17名女孩(年龄:11-16岁)因急性腹痛接受治疗,术中诊断为IFTT。所有患者均接受了腹腔镜探查,并在腹腔镜下进行了输卵管剥离术。根据输卵管疏通术后IFTT与HSX的相关性,患者被分为两组:第1组(无HSX的IFTT;12名女孩)和第2组(有HSX的IFTT;5名女孩)。在同一手术中,还进行了辅助手术。第一组:行输卵管切除术(4 例)、输卵管部分切除术(2 例)和膀胱切除术(6 例)。第二组:输卵管切除术(1)、输卵管切开术(1)和囊肿消融术(1)。第 1 组的随访情况良好。 第 2 组中,所有初次保留输卵管的患者都需要进一步手术治疗(1-4 次手术/患者),最后,另有 3 名患者需要进行输卵管切除术:结论:与有HSX的患者相比,对无HSX的IFTT患者采取保留输卵管的保守治疗似乎是有益的,在随访期间没有再出现扭转或症状。结论:与有HSX的IFTT患者相比,保留输卵管的保守治疗似乎是有益的,随访期间无扭转或症状复发,但同样的保守治疗对有HSX的IFTT患者效果不佳,因扭转复发而需要进一步手术:证据等级:IV。
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引用次数: 0
Comparing Leadership Skills of Senior Emergency Medicine Residents in 3-Year Versus 4-Year Programs During Simulated Pediatric Resuscitation: A Pilot Study. 比较 3 年制与 4 年制急诊医学专业高年级住院医师在模拟儿科复苏过程中的领导技能:试点研究。
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-05-30 DOI: 10.1097/PEC.0000000000003216
Kyle Schoppel, Ashley Keilman, Jabeen Fayyaz, Patricia Padlipsky, Maria Carmen G Diaz, Robyn Wing, Mary Hughes, Marleny Franco, Nathan Swinger, Travis Whitfill, Barbara Walsh

Objectives: The majority of pediatric patients in the United States (US) are evaluated and treated at general emergency departments. It is possible that discrepancies in length of emergency medicine (EM) residency training may allow for variable exposure to pediatric patients, critical resuscitations, and didactic events. The goal of this pilot study was to compare leadership skills of graduating EM residents from 3- to 4-year programs during simulated pediatric resuscitations using a previously validated leadership assessment tool, the Concise Assessment of Leader Management (CALM).

Methods: This was a prospective, multicenter, simulation-based cohort pilot study that included graduating 3 rd - and 4 th -year EM resident physicians from 6 EM residency programs. We measured leadership performance across 3 simulated pediatric resuscitations (sepsis, seizure, cardiac arrest) using the CALM tool and compared leadership scores between the 3 rd - and 4 th -year resident cohorts. We also correlated leadership to self-efficacy scores.

Results: Data was analyzed for 47 participating residents (24 3 rd -year residents and 23 4 th -year residents). Out of a total possible CALM score of 66, residents from 3-year programs scored 45.2 [SD ± 5.2], 46.8 [SD ± 5.0], and 46.6 [SD ± 4.7], whereas residents from 4-year programs scored 45.5 [SD ± 5.2], 46.4 [SD ± 5.0], and 48.2 [SD ± 4.3] during the sepsis, seizure, and cardiac arrest cases, respectively. The mean leadership score across all 3 cases for the 3-year cohort was 46.2 [SD ± 4.8] versus 46.7 [SD ± 4.5] ( P = 0.715) for the 4-year cohort.

Conclusions: These data show feasibility for a larger cohort project and, while not statistically significant, suggest no difference in leadership skills between 3 rd - and 4 th -year EM residents in our study cohort. This pilot study provides the basis of future work that will assess a larger multicenter cohort with the hope to obtain a more generalizable dataset.

目的:在美国,大多数儿科病人都在普通急诊科接受评估和治疗。急诊医学(EM)住院医师培训时间的长短不一,可能会导致接触儿科患者、危重抢救和教学活动的机会不同。本试验研究的目的是使用之前经过验证的领导力评估工具--"领导力管理简明评估"(CALM)--比较三年制和四年制急诊科毕业住院医师在模拟儿科复苏过程中的领导力技能:这是一项前瞻性、多中心、基于模拟的队列试点研究,包括来自 6 个急救住院医师培训项目的即将毕业的三年级和四年级急救住院医师。我们使用 CALM 工具测量了 3 个模拟儿科复苏(败血症、癫痫发作、心脏骤停)中的领导力表现,并比较了三年级和四年级住院医师的领导力得分。我们还将领导力与自我效能得分相关联:我们对 47 名参与研究的住院医师(24 名三年级住院医师和 23 名四年级住院医师)进行了数据分析。在 66 分的 CALM 总分中,3 年制住院医师在败血症、癫痫发作和心脏骤停病例中的得分分别为 45.2 [SD ± 5.2]、46.8 [SD ± 5.0] 和 46.6 [SD ± 4.7],而 4 年制住院医师的得分分别为 45.5 [SD ± 5.2]、46.4 [SD ± 5.0] 和 48.2 [SD ± 4.3]。3 年队列中所有 3 个病例的平均领导力评分为 46.2 [SD ± 4.8],而 4 年队列中的平均领导力评分为 46.7 [SD ± 4.5](P = 0.715):这些数据显示了更大规模队列项目的可行性,尽管在统计学上并不显著,但表明在我们的研究队列中,三年级和四年级的急诊科住院医师在领导技能方面并无差异。这项试点研究为今后的工作奠定了基础,今后将对更大规模的多中心队列进行评估,希望能获得更具普遍性的数据集。
{"title":"Comparing Leadership Skills of Senior Emergency Medicine Residents in 3-Year Versus 4-Year Programs During Simulated Pediatric Resuscitation: A Pilot Study.","authors":"Kyle Schoppel, Ashley Keilman, Jabeen Fayyaz, Patricia Padlipsky, Maria Carmen G Diaz, Robyn Wing, Mary Hughes, Marleny Franco, Nathan Swinger, Travis Whitfill, Barbara Walsh","doi":"10.1097/PEC.0000000000003216","DOIUrl":"10.1097/PEC.0000000000003216","url":null,"abstract":"<p><strong>Objectives: </strong>The majority of pediatric patients in the United States (US) are evaluated and treated at general emergency departments. It is possible that discrepancies in length of emergency medicine (EM) residency training may allow for variable exposure to pediatric patients, critical resuscitations, and didactic events. The goal of this pilot study was to compare leadership skills of graduating EM residents from 3- to 4-year programs during simulated pediatric resuscitations using a previously validated leadership assessment tool, the Concise Assessment of Leader Management (CALM).</p><p><strong>Methods: </strong>This was a prospective, multicenter, simulation-based cohort pilot study that included graduating 3 rd - and 4 th -year EM resident physicians from 6 EM residency programs. We measured leadership performance across 3 simulated pediatric resuscitations (sepsis, seizure, cardiac arrest) using the CALM tool and compared leadership scores between the 3 rd - and 4 th -year resident cohorts. We also correlated leadership to self-efficacy scores.</p><p><strong>Results: </strong>Data was analyzed for 47 participating residents (24 3 rd -year residents and 23 4 th -year residents). Out of a total possible CALM score of 66, residents from 3-year programs scored 45.2 [SD ± 5.2], 46.8 [SD ± 5.0], and 46.6 [SD ± 4.7], whereas residents from 4-year programs scored 45.5 [SD ± 5.2], 46.4 [SD ± 5.0], and 48.2 [SD ± 4.3] during the sepsis, seizure, and cardiac arrest cases, respectively. The mean leadership score across all 3 cases for the 3-year cohort was 46.2 [SD ± 4.8] versus 46.7 [SD ± 4.5] ( P = 0.715) for the 4-year cohort.</p><p><strong>Conclusions: </strong>These data show feasibility for a larger cohort project and, while not statistically significant, suggest no difference in leadership skills between 3 rd - and 4 th -year EM residents in our study cohort. This pilot study provides the basis of future work that will assess a larger multicenter cohort with the hope to obtain a more generalizable dataset.</p>","PeriodicalId":19996,"journal":{"name":"Pediatric emergency care","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
POCUS for Infectious Enteritis-A Retrospective Case Series Analysis. POCUS 治疗感染性肠炎--回顾性病例系列分析。
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-02-28 DOI: 10.1097/PEC.0000000000003139
Eric Scheier, Aviad Nachmany

Introduction: The abdominal pain associated with diarrhea can be difficult to distinguish from appendicitis. We present a case series of all children found on pediatric emergency department point-of-care ultrasound (POCUS) to have right-sided bowel wall edema.

Methods: Over the study period June 2020 through September 2023, POCUS images were collected by a pediatric emergency physician with 6 years of experience with POCUS. Children found to have small bowel wall edema on POCUS were identified, and hospital charts were reviewed.

Results: One hundred thirteen children were found on POCUS to have right-sided small bowel wall edema. Thirty-one (27%) were referred by their pediatrician or urgent care provider to evaluate for appendicitis. Seventy-eight children (69%) provided stool samples. Of those, 58% resulted Campylobacter , 8% Salmonella , and 8% Shigella . Forty (35%) were discharged after POCUS without further evaluation. One child in our case series was subsequently diagnosed with uncomplicated appendicitis. To date, no child in the series has subsequently been diagnosed with inflammatory bowel disease.

Conclusions: Enteritis can initially be difficult to distinguish on clinical grounds from acute appendicitis. Bowel wall edema on POCUS in a child without sonographic signs of appendicitis strongly suggests bacterial enteritis. Early POCUS demonstrating enteritis without signs of appendicitis may decrease hospital resource usage.

导言:腹泻引起的腹痛很难与阑尾炎相鉴别。我们对儿科急诊室护理点超声检查(POCUS)发现右侧肠壁水肿的所有患儿进行了病例系列研究:方法:在 2020 年 6 月至 2023 年 9 月的研究期间,由一名具有 6 年 POCUS 经验的儿科急诊医生收集 POCUS 图像。确定在 POCUS 上发现小肠壁水肿的儿童,并审查医院病历:结果:113 名儿童经 POCUS 检查发现右侧小肠壁水肿。31名儿童(27%)由儿科医生或紧急护理提供者转诊,以评估是否患有阑尾炎。78名儿童(69%)提供了粪便样本。在这些样本中,58%为弯曲杆菌,8%为沙门氏菌,8%为志贺氏杆菌。40名患儿(35%)在POCUS检查后出院,未做进一步评估。在我们的病例系列中,有一名患儿随后被诊断为无并发症阑尾炎。迄今为止,该系列病例中没有一名患儿后来被诊断为炎症性肠病:结论:肠炎与急性阑尾炎在临床上很难区分。对于没有阑尾炎声像图征象的患儿,POCUS 显示肠壁水肿强烈提示细菌性肠炎。早期 POCUS 显示肠炎而无阑尾炎体征可减少医院资源的使用。
{"title":"POCUS for Infectious Enteritis-A Retrospective Case Series Analysis.","authors":"Eric Scheier, Aviad Nachmany","doi":"10.1097/PEC.0000000000003139","DOIUrl":"10.1097/PEC.0000000000003139","url":null,"abstract":"<p><strong>Introduction: </strong>The abdominal pain associated with diarrhea can be difficult to distinguish from appendicitis. We present a case series of all children found on pediatric emergency department point-of-care ultrasound (POCUS) to have right-sided bowel wall edema.</p><p><strong>Methods: </strong>Over the study period June 2020 through September 2023, POCUS images were collected by a pediatric emergency physician with 6 years of experience with POCUS. Children found to have small bowel wall edema on POCUS were identified, and hospital charts were reviewed.</p><p><strong>Results: </strong>One hundred thirteen children were found on POCUS to have right-sided small bowel wall edema. Thirty-one (27%) were referred by their pediatrician or urgent care provider to evaluate for appendicitis. Seventy-eight children (69%) provided stool samples. Of those, 58% resulted Campylobacter , 8% Salmonella , and 8% Shigella . Forty (35%) were discharged after POCUS without further evaluation. One child in our case series was subsequently diagnosed with uncomplicated appendicitis. To date, no child in the series has subsequently been diagnosed with inflammatory bowel disease.</p><p><strong>Conclusions: </strong>Enteritis can initially be difficult to distinguish on clinical grounds from acute appendicitis. Bowel wall edema on POCUS in a child without sonographic signs of appendicitis strongly suggests bacterial enteritis. Early POCUS demonstrating enteritis without signs of appendicitis may decrease hospital resource usage.</p>","PeriodicalId":19996,"journal":{"name":"Pediatric emergency care","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139983502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Variations in Management and Clinical Outcomes for Children With Diabetic Ketoacidosis in an Academic Pediatric Versus Community Emergency Department Setting. 儿科学术机构与社区急诊室对糖尿病酮症酸中毒患儿的管理和临床结果存在差异。
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-04-02 DOI: 10.1097/PEC.0000000000003197
John Nathan Freeman, Callie Giroux, Timothy King, Christina Marbrey, Matthew Maready, Simeen Pasha, Justin Davis

Objectives: Our objectives were to characterize variations from standardized, evidence-based guidelines in the management of pediatric patients with diabetic ketoacidosis (DKA) based on initial presentation to a tertiary pediatric emergency department (PED) versus a community emergency department (OSH) and compare clinical outcomes.

Methods: We conducted a retrospective study on children 18 years and younger with DKA who presented to an OSH or PED over a 3-year period. Treatments monitored for variation included intravenous fluid management, insulin delivery, and sodium bicarbonate administrations. Clinical outcomes included time to anion gap correction and on insulin infusion, hypokalemia, hypoglycemia, rapid serum glucose decline, cerebral edema, mechanical ventilation, mortality, and time from initial presentation to hospital discharge.

Results: Children with DKA who presented to an OSH (n = 250) were more acidotic (pH 7.11 vs. 7.13, P = 0.001) and had larger anion gaps (28.8 vs. 25.5, P < 0.001) compared with children presenting to the PED (n = 237). The OSH patients were more likely to receive larger fluid boluses (>20 cc/kg or >1000 ml, 43% vs. 4%, P < 0.001), sodium bicarbonate (5% vs. 0%, P < 0.001), and intravenous bolus insulin (28% vs. 0%, P < 0.001). The OSH group were less likely to be started on maintenance intravenous fluids (70% vs. 99%, P < 0.001) or receive potassium in maintenance intravenous fluids (14% vs. 42%, P < 0.001). The OSH group had longer anion gap correction times (754 vs. 541 mins, P < 0.001), insulin infusion times (1018 vs. 854 min, P = 0.003), and times to hospital discharge (3358 vs. 3045 mins, P < 0.001). Incidence of hypokalemia, hypoglycemia, rapid glucose decline, cerebral edema, and deaths were similar between the 2 groups.

Conclusions: Our study demonstrated significant variations in the initial management of pediatric DKA patients by OSH facilities that deviated from an evidence-based treatment pathway utilized by a PED. Statewide quality improvement initiatives could help improve the overall clinical care provided to pediatric DKA patients.

目标:我们的目的是根据初次到三级儿科急诊科(PED)和社区急诊科(OSH)就诊的情况,分析儿科糖尿病酮症酸中毒(DKA)患者的管理与标准化循证指南之间的差异,并比较临床结果:方法:我们对3年内到OSH或PED就诊的18岁及以下DKA患儿进行了一项回顾性研究。监测变化的治疗方法包括静脉输液管理、胰岛素给药和碳酸氢钠给药。临床结果包括阴离子间隙纠正时间和胰岛素输注时间、低钾血症、低血糖、血清葡萄糖快速下降、脑水肿、机械通气、死亡率以及从初诊到出院的时间:与在PED就诊的患儿(n = 237)相比,在OSH就诊的DKA患儿(n = 250)酸度更高(pH值为7.11 vs. 7.13,P = 0.001),阴离子缺口更大(28.8 vs. 25.5,P < 0.001)。OSH患者更有可能接受更大量的栓注液体(>20 cc/kg 或 >1000 ml,43% 对 4%,P < 0.001)、碳酸氢钠(5% 对 0%,P < 0.001)和静脉栓注胰岛素(28% 对 0%,P < 0.001)。OSH 组较少开始静脉输液(70% 对 99%,P<0.001)或在静脉输液中补充钾(14% 对 42%,P<0.001)。OSH 组阴离子间隙校正时间(754 分钟对 541 分钟,P < 0.001)、胰岛素输注时间(1018 分钟对 854 分钟,P = 0.003)和出院时间(3358 分钟对 3045 分钟,P < 0.001)更长。两组患者的低钾血症、低血糖、血糖快速下降、脑水肿和死亡发生率相似:我们的研究表明,OSH 机构对小儿 DKA 患者的初始管理存在很大差异,与 PED 采用的循证治疗路径存在偏差。全州范围内的质量改进措施有助于改善为儿科 DKA 患者提供的整体临床护理。
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引用次数: 0
Incidence of Bacteremia and Serious Bacterial Infections in Hyperpyrexic Infants Offered Universal Pneumococcal Conjugate Vaccine 13 and Haemophilus influenzae B Immunization. 接受肺炎球菌结合疫苗 13 和 B 型流感嗜血杆菌免疫接种的高热婴儿中菌血症和严重细菌感染的发生率。
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-05-23 DOI: 10.1097/PEC.0000000000003217
Moria Be'er, Ayelet Rimon, Or Segev, Adi Huber, Dennis Scolnik, Miguel Glatstein

Background: High fevers, especially in young children, often alarm clinicians and prompt extensive evaluation based on perceptions of increased risk of serious bacterial infection (SBI), and even brain damage or seizure disorders.

Objective: The aim of this study was to determine the prevalence of SBI in infants aged 3-36 months with fever ≥40.5°C in a population of infants offered universal pneumococcal conjugate vaccine 13 and Haemophilus influenzae B immunization.

Methods: This study is a retrospective review of all infants aged 3-36 months with temperature ≥40.5°C presenting to a tertiary care pediatric emergency department over a 30-month period in an era of universal pneumococcal conjugate 13 and H. influenzae B immunization.

Results: SBI was recorded in 54 (21.8%) of 247 study infants, most commonly pneumonia 30 patients (12.1%) and urinary tract infection 16 patients (6.5%). Two patients had positive blood cultures, yielding a bacteremia rate of 0.8%. Patients with SBI had a significantly higher WBC count ( P < 0.0001) and C-reactive protein levels ( P < 0.0001), and were significantly more likely to be hospitalized ( P < 0.0001).

Discussion: Although SBI was common (21.8%) in our cohort of hyperpyrexic infants universally offered vaccination with pneumococcal conjugate 13 and H. influenzae B vaccines, bacteremia was a rare finding (0.8%).

背景:高烧(尤其是幼儿高烧)通常会引起临床医生的警觉,并在认为严重细菌感染(SBI)、甚至脑损伤或癫痫发作风险增加的基础上进行广泛评估:本研究旨在确定在接受肺炎球菌结合疫苗 13 和 B 型流感嗜血杆菌免疫接种的 3-36 个月婴儿中,发热≥40.5°C 的 SBI 患病率:本研究是一项回顾性研究,研究对象是在普及肺炎球菌结合疫苗13和流感嗜血杆菌B免疫接种的30个月期间,在一家三级医疗机构儿科急诊科就诊的所有体温≥40.5°C的3-36个月婴儿:在 247 名研究对象中,有 54 名婴儿(21.8%)发生了 SBI,其中最常见的是肺炎 30 例(12.1%)和尿路感染 16 例(6.5%)。两名患者血液培养呈阳性,菌血症发生率为 0.8%。SBI患者的白细胞计数(P<0.0001)和C反应蛋白水平(P<0.0001)明显升高,住院的可能性也明显增加(P<0.0001):讨论:虽然在我们的高热惊厥婴儿队列中,普遍接种肺炎球菌结合疫苗 13 和乙型流感嗜血杆菌疫苗的 SBI 很常见(21.8%),但菌血症却很少见(0.8%)。
{"title":"Incidence of Bacteremia and Serious Bacterial Infections in Hyperpyrexic Infants Offered Universal Pneumococcal Conjugate Vaccine 13 and Haemophilus influenzae B Immunization.","authors":"Moria Be'er, Ayelet Rimon, Or Segev, Adi Huber, Dennis Scolnik, Miguel Glatstein","doi":"10.1097/PEC.0000000000003217","DOIUrl":"10.1097/PEC.0000000000003217","url":null,"abstract":"<p><strong>Background: </strong>High fevers, especially in young children, often alarm clinicians and prompt extensive evaluation based on perceptions of increased risk of serious bacterial infection (SBI), and even brain damage or seizure disorders.</p><p><strong>Objective: </strong>The aim of this study was to determine the prevalence of SBI in infants aged 3-36 months with fever ≥40.5°C in a population of infants offered universal pneumococcal conjugate vaccine 13 and Haemophilus influenzae B immunization.</p><p><strong>Methods: </strong>This study is a retrospective review of all infants aged 3-36 months with temperature ≥40.5°C presenting to a tertiary care pediatric emergency department over a 30-month period in an era of universal pneumococcal conjugate 13 and H. influenzae B immunization.</p><p><strong>Results: </strong>SBI was recorded in 54 (21.8%) of 247 study infants, most commonly pneumonia 30 patients (12.1%) and urinary tract infection 16 patients (6.5%). Two patients had positive blood cultures, yielding a bacteremia rate of 0.8%. Patients with SBI had a significantly higher WBC count ( P < 0.0001) and C-reactive protein levels ( P < 0.0001), and were significantly more likely to be hospitalized ( P < 0.0001).</p><p><strong>Discussion: </strong>Although SBI was common (21.8%) in our cohort of hyperpyrexic infants universally offered vaccination with pneumococcal conjugate 13 and H. influenzae B vaccines, bacteremia was a rare finding (0.8%).</p>","PeriodicalId":19996,"journal":{"name":"Pediatric emergency care","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141081891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracorporeal Cardiopulmonary Resuscitation: CME Review. 体外心肺复苏:CME 回顾。
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-08-01 DOI: 10.1097/PEC.0000000000003178
Michael Stratton, Katherine Edmunds

Abstract: Extracorporeal cardiopulmonary resuscitation (eCPR) is increasingly being used for refractory cardiac arrest for both in-hospital and out-of-hospital cardiac arrests. The term eCPR refers to cannulating a patient to an extracorporeal membrane oxygenation (ECMO) circuit to provide perfusion after cardiac arrest refractory to standard cardiopulmonary resuscitation. Extracorporeal cardiopulmonary resuscitation has been shown to offer increased survival benefit among a select group of adult and pediatric patients experiencing refractory cardiac arrests, both in hospital and out of hospital. Extracorporeal cardiopulmonary resuscitation should be considered when (1) the cardiac arrest is witnessed, (2) the patient receives high-quality cardiopulmonary resuscitation, (3) the patient is at or in close proximity to an ECMO center, (4) there is a reversible cause for the cardiac arrest where the perfusion from the ECMO circuit serves as a bridge to recovery, and (5) the treating facility has a robust multidisciplinary system in place to facilitate rapidly moving patients from site of arrest to site of cannulation to intensive care unit. To develop an eCPR system of care, a multidisciplinary team consisting of prehospital, emergency medicine, in-hospital, proceduralist, perfusionist, and intensive care medical professionals must be established who support the use of eCPR for refractory cardiac arrest. The future of eCPR is the development of systems of care that use eCPR for a narrow subset of pediatric out-of-hospital cardiac arrests.

摘要:体外心肺复苏(eCPR)越来越多地用于院内和院外的难治性心脏骤停。所谓 eCPR,是指在标准心肺复苏术难治性心脏骤停后,为患者插管至体外膜肺氧合(ECMO)回路,以提供灌注。事实证明,体外心肺复苏术可提高部分难治性心脏骤停成人和儿童患者的存活率,无论是在医院内还是在医院外。在以下情况下应考虑进行体外心肺复苏:(1) 有人目击心脏骤停;(2) 病人接受了高质量的心肺复苏;(3) 病人在 ECMO 中心或邻近 ECMO 中心、(4) 心脏骤停的原因是可逆的,ECMO 循环灌注可作为恢复的桥梁;以及 (5) 治疗机构拥有强大的多学科系统,可快速将患者从骤停地点转移到插管地点,再转移到重症监护室。要建立 eCPR 护理系统,必须建立一个由院前、急诊医学、院内、程序学家、灌注学家和重症监护医学专家组成的多学科团队,支持使用 eCPR 治疗难治性心脏骤停。eCPR 的未来是发展护理系统,将 eCPR 用于小范围的儿科院外心脏骤停。
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引用次数: 0
Usability Testing Via Simulation: Optimizing the NEAR4PEM Preintubation Checklist With a Human Factors Approach. 通过模拟进行可用性测试:采用人为因素方法优化 NEAR4PEM 插管前检查表
IF 1.2 4区 医学 Q3 EMERGENCY MEDICINE Pub Date : 2024-08-01 Epub Date: 2024-07-27 DOI: 10.1097/PEC.0000000000003223
Robyn Wing, Michael P Goldman, Monica M Prieto, Kelsey A Miller, Mariju Baluyot, Khoon-Yen Tay, Anita Bharath, Deepa Patel, Emily Greenwald, Ethan P Larsen, Lee A Polikoff, Benjamin T Kerrey, Akira Nishisaki, Joshua Nagler

Objectives: To inform development of a preintubation checklist for pediatric emergency departments via multicenter usability testing of a prototype checklist.

Methods: This was a prospective, mixed methods study across 7 sites in the National Emergency Airway Registry for Pediatric Emergency Medicine (NEAR4PEM) collaborative. Pediatric emergency medicine attending physicians and senior fellows at each site were first oriented to a checklist prototype, including content previously identified using a modified Delphi approach. Each site used the checklist in 2 simulated cases: an "easy airway" and a "difficult airway" scenario. Facilitators recorded verbalization, completion, and timing of checklist items. After each simulation, participants completed an anonymous usability survey. Structured debriefings were used to gather additional feedback on checklist usability. Comments from the surveys and debriefing were qualitatively analyzed using a framework approach. Responses informed human factors-based optimization of the checklist.

Results: Fifty-five pediatric emergency medicine physicians/fellows (4-13 per site) participated. Participants found the prototype checklist to be helpful, easy to use, clear, and of appropriate length. During the simulations, 93% of checklist items were verbalized and more than 80% were completed. Median time to checklist completion was 6.2 minutes (interquartile range, 4.8-7.1) for the first scenario and 4.2 minutes (interquartile range, 2.7-5.8) for the second. Survey and debriefing data identified the following strengths: facilitating a shared mental model, cognitively offloading the team leader, and prompting contingency planning. Suggestions for checklist improvement included clarifying specific items, providing more detailed prompts, and allowing institution-specific customization. Integration of these data with human factors heuristic inspection resulted in a final checklist.

Conclusions: Simulation-based, human factors usability testing of the National Emergency Airway Registry for Pediatric Emergency Medicine Preintubation Checklist allowed optimization prior to clinical implementation. Next steps involve integration into real-world settings utilizing rigorous implementation science strategies, with concurrent evaluation of the impact on patient outcomes and safety.

目的通过对原型核对表进行多中心可用性测试,为儿科急诊科插管前核对表的开发提供信息:这是一项前瞻性的混合方法研究,涉及全国儿科急诊气道注册(NEAR4PEM)合作的 7 个站点。各研究机构的儿科急诊医学主治医师和高级研究员首先了解了核对表原型,包括之前通过改良德尔菲法确定的内容。每个培训基地在 2 个模拟病例中使用核对表:"简易气道 "和 "困难气道 "情景。主持人记录核对表项目的口头表达、完成情况和时间。每次模拟后,参与者都要填写一份匿名可用性调查。结构化汇报用于收集有关核对表可用性的更多反馈。采用框架方法对调查和汇报中的意见进行了定性分析。结果:55名儿科急诊科医生/研究员(每个地点4-13名)参加了此次活动。参与者认为原型核对表很有帮助、易于使用、清晰明了、长度适当。在模拟过程中,93% 的核对表项目得到了口头表达,80% 以上的项目得以完成。完成核对表的中位时间为:第一种情景 6.2 分钟(四分位数间距为 4.8-7.1),第二种情景 4.2 分钟(四分位数间距为 2.7-5.8)。调查和汇报数据发现了以下优点:促进形成共同的心智模式、在认知上减轻团队领导者的负担以及促使制定应急计划。对核对表的改进建议包括:明确具体项目、提供更详细的提示以及允许针对特定机构进行定制。将这些数据与人为因素启发式检查相结合,最终形成了检查表:结论:在临床实施之前,对全国儿科急诊气道注册中心插管前核对表进行了基于模拟的人为因素可用性测试,从而对核对表进行了优化。接下来的步骤包括利用严格的实施科学策略将其整合到实际环境中,同时评估其对患者预后和安全性的影响。
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引用次数: 0
期刊
Pediatric emergency care
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