The article analyses an original database of 177 Latin American women activists killed that had some connection with feminist social movements from 2015 to 2023. A growing body of literature has focused on the killings of socio-environmental activists in Latin America and where they occurred. However, their activisms are under-researched, precisely because feminist social movements and activists have frequently been killed while advocating for women’s rights in the subcontinent. This article focuses on the circumstances, a few reasons portrayed in newspaper events, and the perpetrators of such violence. Based on a literature review, I argue that taking into account the recent narcodynamics of the region, it is possible to understand such violence within the context of drug-related violence, but also—and more likely—to consider those killings as political feminicides. Political feminicides are then examined largely through transfeminicides and peasant/communitarian activists.