首页 > 最新文献

Pharmacophore最新文献

英文 中文
Cloning and Expression of Receptor of Egg Jelly Protein of Polycystic Kidney Disease 1 Gene in Human Receptor of Egg Jelly Protein 人多囊肾病蛋冻蛋白受体1基因的克隆与表达
IF 0.5 Pub Date : 2022-01-01 DOI: 10.51847/vqghabllgj
H. S. Sonbol, Aljazi Abdullah AlRashidi
{"title":"Cloning and Expression of Receptor of Egg Jelly Protein of Polycystic Kidney Disease 1 Gene in Human Receptor of Egg Jelly Protein","authors":"H. S. Sonbol, Aljazi Abdullah AlRashidi","doi":"10.51847/vqghabllgj","DOIUrl":"https://doi.org/10.51847/vqghabllgj","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70837018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between Pre-Existing Conditions in Covid-19 Patients and Inflammation Covid-19患者既往状况与炎症的关系
IF 0.5 Pub Date : 2022-01-01 DOI: 10.51847/vsosr2f5dn
L. Fritea, Maruzella Sipponen, A. Antonescu, F. Miere, R. Chirla, C. Vesa, S. Cavalu, M. Ganea, T. Horváth, C. Petcheși, M. Domuța
COVID-19 is characterized by a strong inflammatory response leading to specific changes in the immune system cell counts. In this study, the following biomarkers from the laboratory data of COVID-19 patients have been analyzed: white blood cells (WBC), neutrophils, lymphocytes, monocytes, eosinophils, basophils, C-reactive protein, and glycemia. Various comparisons, correlations, and ratios between these inflammatory biomarkers have been performed to assess the link between pre-existing conditions and the various blood markers, as well as the disease severity. WBC, neutrophils, C-reactive protein, and glycemia had high levels in more than 60-70% of the patients, although diabetic patients had even higher glycemia levels (p<0.05). A high correlation was found between WBC and neutrophils which dominate the WBC count, and a more moderate one between lymphocytes and monocytes. Lymphocyte, monocyte, and basophil counts were lower in patients with comorbidities in general, while lymphocytes and monocytes were also lower in the subset of patients with diabetes in particular (p<0.05). The means and medians of all the aforementioned hematological parameters have been calculated for each subset of pre-existing conditions. Copyright (C) 2013 - All Rights Reserved - Pharmacophore
COVID-19的特点是强烈的炎症反应,导致免疫系统细胞计数发生特异性变化。本研究分析了COVID-19患者实验室数据中的以下生物标志物:白细胞(WBC)、中性粒细胞、淋巴细胞、单核细胞、嗜酸性粒细胞、嗜碱性粒细胞、c反应蛋白和血糖。在这些炎症生物标志物之间进行了各种比较、相关性和比率,以评估预先存在的疾病与各种血液标志物以及疾病严重程度之间的联系。WBC、中性粒细胞、c反应蛋白和血糖水平在60-70%以上的患者中较高,糖尿病患者的血糖水平更高(p<0.05)。白细胞与中性粒细胞之间存在高度相关性,中性粒细胞在白细胞计数中占主导地位,而淋巴细胞与单核细胞之间的相关性更为温和。淋巴细胞、单核细胞和嗜碱性细胞计数在合并症患者中普遍较低,而淋巴细胞和单核细胞计数在糖尿病患者中也较低(p<0.05)。所有上述血液学参数的平均值和中位数已被计算为预先存在的条件的每个子集。版权所有-药典药业有限公司
{"title":"Relationship between Pre-Existing Conditions in Covid-19 Patients and Inflammation","authors":"L. Fritea, Maruzella Sipponen, A. Antonescu, F. Miere, R. Chirla, C. Vesa, S. Cavalu, M. Ganea, T. Horváth, C. Petcheși, M. Domuța","doi":"10.51847/vsosr2f5dn","DOIUrl":"https://doi.org/10.51847/vsosr2f5dn","url":null,"abstract":"COVID-19 is characterized by a strong inflammatory response leading to specific changes in the immune system cell counts. In this study, the following biomarkers from the laboratory data of COVID-19 patients have been analyzed: white blood cells (WBC), neutrophils, lymphocytes, monocytes, eosinophils, basophils, C-reactive protein, and glycemia. Various comparisons, correlations, and ratios between these inflammatory biomarkers have been performed to assess the link between pre-existing conditions and the various blood markers, as well as the disease severity. WBC, neutrophils, C-reactive protein, and glycemia had high levels in more than 60-70% of the patients, although diabetic patients had even higher glycemia levels (p<0.05). A high correlation was found between WBC and neutrophils which dominate the WBC count, and a more moderate one between lymphocytes and monocytes. Lymphocyte, monocyte, and basophil counts were lower in patients with comorbidities in general, while lymphocytes and monocytes were also lower in the subset of patients with diabetes in particular (p<0.05). The means and medians of all the aforementioned hematological parameters have been calculated for each subset of pre-existing conditions. Copyright (C) 2013 - All Rights Reserved - Pharmacophore","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70837488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Morphologic Characterization of Atherosclerotic Plaque of Coronary Arteries Diseases by Multidetector Computed Tomography (MDCT) 冠状动脉粥样硬化斑块的多探测器计算机断层扫描形态学特征
IF 0.5 Pub Date : 2022-01-01 DOI: 10.51847/w8eispcooo
M. Salih, Elgeili Yousif, E. Elnour, Mogahid M. A. Zidan, A. Abukonna, Mohamed Yousef, Shashikumar Channmege Govindappa, M. Alshammari, Amjad R. Alyahyawi, Q. Alshammari
{"title":"Morphologic Characterization of Atherosclerotic Plaque of Coronary Arteries Diseases by Multidetector Computed Tomography (MDCT)","authors":"M. Salih, Elgeili Yousif, E. Elnour, Mogahid M. A. Zidan, A. Abukonna, Mohamed Yousef, Shashikumar Channmege Govindappa, M. Alshammari, Amjad R. Alyahyawi, Q. Alshammari","doi":"10.51847/w8eispcooo","DOIUrl":"https://doi.org/10.51847/w8eispcooo","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70838203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Frequency and Efficiency of the Application of Online Sources for Searching Drug Information and Self-Treatment 网上药物信息检索和自我治疗资源的使用频率和效率
IF 0.5 Pub Date : 2022-01-01 DOI: 10.51847/6u1mi7a1wj
Maria Sergeevna Soboleva
{"title":"The Frequency and Efficiency of the Application of Online Sources for Searching Drug Information and Self-Treatment","authors":"Maria Sergeevna Soboleva","doi":"10.51847/6u1mi7a1wj","DOIUrl":"https://doi.org/10.51847/6u1mi7a1wj","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70813315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Association between Trauma and the Occurrence of Diabetes Mellitus at the Age of Less than 40 Years 创伤与40岁以下糖尿病发生的关系
IF 0.5 Pub Date : 2022-01-01 DOI: 10.51847/d3qymubfwj
A. Sharifi, Asayel Alqahtani, I. H. Almousaedi, S. Almotadaris, Ahmed Abdullah Yahya Ojaym, Mushabbab Ali M Al Alnuayr, Awadh Mohammed Al Antar, Hanadi Tikhtikh Alaqidi, E. Osaili, S. Alamri
{"title":"The Association between Trauma and the Occurrence of Diabetes Mellitus at the Age of Less than 40 Years","authors":"A. Sharifi, Asayel Alqahtani, I. H. Almousaedi, S. Almotadaris, Ahmed Abdullah Yahya Ojaym, Mushabbab Ali M Al Alnuayr, Awadh Mohammed Al Antar, Hanadi Tikhtikh Alaqidi, E. Osaili, S. Alamri","doi":"10.51847/d3qymubfwj","DOIUrl":"https://doi.org/10.51847/d3qymubfwj","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70818011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Role of Physiotherapy in the Management of Lymphoma Patients: Systematic Review 物理治疗在淋巴瘤患者治疗中的作用:系统综述
IF 0.5 Pub Date : 2022-01-01 DOI: 10.51847/dauh9lwbfl
Saif Habib Mahmoud Jerbi, S. N. Alanazi, W. Alanazi, Alanazi Yasser Hamoud Mutlaq, Freh Sayah Mezal Alotaibi, Maha Afat Hnde Alenezi
{"title":"The Role of Physiotherapy in the Management of Lymphoma Patients: Systematic Review","authors":"Saif Habib Mahmoud Jerbi, S. N. Alanazi, W. Alanazi, Alanazi Yasser Hamoud Mutlaq, Freh Sayah Mezal Alotaibi, Maha Afat Hnde Alenezi","doi":"10.51847/dauh9lwbfl","DOIUrl":"https://doi.org/10.51847/dauh9lwbfl","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70818261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Efficacy of Various Oral Wound Dressing Materials; A Systematic Review 不同口腔创面敷料的临床疗效观察系统回顾
IF 0.5 Pub Date : 2022-01-01 DOI: 10.51847/edd51jveyi
Suhael Ahmed, Elham Yaqub, A. Almalik, Malak Aljuhani, Rawan Alrrashod
{"title":"Clinical Efficacy of Various Oral Wound Dressing Materials; A Systematic Review","authors":"Suhael Ahmed, Elham Yaqub, A. Almalik, Malak Aljuhani, Rawan Alrrashod","doi":"10.51847/edd51jveyi","DOIUrl":"https://doi.org/10.51847/edd51jveyi","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70819394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Aetiology of Bacterial Infections and Antibiotic Resistance in Pediatric Patients from a Romanian Hospital 罗马尼亚一家医院儿科患者细菌感染和抗生素耐药性的病因学分析
IF 0.5 Pub Date : 2022-01-01 DOI: 10.51847/r2feu5ajxs
Lorena Păduraru, A. Jurcă, D. Zaha, F. Dorobanțu, Mădălin Alexandru Hasan, M. Popoviciu
{"title":"Aetiology of Bacterial Infections and Antibiotic Resistance in Pediatric Patients from a Romanian Hospital","authors":"Lorena Păduraru, A. Jurcă, D. Zaha, F. Dorobanțu, Mădălin Alexandru Hasan, M. Popoviciu","doi":"10.51847/r2feu5ajxs","DOIUrl":"https://doi.org/10.51847/r2feu5ajxs","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70832133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MicroRNA-224 Up-regulation: A Risk for Complications in Type 2 Diabetes Mellitus Egyptian Patients MicroRNA-224上调:埃及2型糖尿病患者并发症的风险
IF 0.5 Pub Date : 2022-01-01 DOI: 10.51847/skwtzqgb22
A. Mohamed, D. Abo-Elmatty, O. Esmail, Hadeer Saied Mahmoud Salim, Soha Mahmoud Abd El Salam, Amira R. El-Ansary, Maha F Yacoub, Sherihan Abdelrahman Ibrahim Abdelrahman, O. M. Saleh, Yosra Hassan, Eman Alhussain Abdulgawad, Y. Sakr, A. Wahba
{"title":"MicroRNA-224 Up-regulation: A Risk for Complications in Type 2 Diabetes Mellitus Egyptian Patients","authors":"A. Mohamed, D. Abo-Elmatty, O. Esmail, Hadeer Saied Mahmoud Salim, Soha Mahmoud Abd El Salam, Amira R. El-Ansary, Maha F Yacoub, Sherihan Abdelrahman Ibrahim Abdelrahman, O. M. Saleh, Yosra Hassan, Eman Alhussain Abdulgawad, Y. Sakr, A. Wahba","doi":"10.51847/skwtzqgb22","DOIUrl":"https://doi.org/10.51847/skwtzqgb22","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70833898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous Evaluation of Amlodipine Besylate and Candesartan Cilexetil by Applying Chemometric Assisted Spectrophotometric Method 化学计量辅助分光光度法同时评价苯磺酸氨氯地平和坎地沙坦西蕾蒂酯
IF 0.5 Pub Date : 2022-01-01 DOI: 10.51847/w6hzzfmimj
M. Hinge, D. Patel, Megha Shah
Received: 25 Oct 2021 Received in revised form: 06 Jan 2022 Accepted: 10 Jan 2022 Available online: 28 Feb 2022
收稿日期:2021年10月25日收稿日期:2022年1月06日接收日期:2022年1月10日在线发布日期:2022年2月28日
{"title":"Simultaneous Evaluation of Amlodipine Besylate and Candesartan Cilexetil by Applying Chemometric Assisted Spectrophotometric Method","authors":"M. Hinge, D. Patel, Megha Shah","doi":"10.51847/w6hzzfmimj","DOIUrl":"https://doi.org/10.51847/w6hzzfmimj","url":null,"abstract":"Received: 25 Oct 2021 Received in revised form: 06 Jan 2022 Accepted: 10 Jan 2022 Available online: 28 Feb 2022","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70838044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Pharmacophore
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1