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Diffusive geodesics wandering in networks of rigid chains. 漫射测地线在刚性链网中游荡。
IF 2.4 3区 物理与天体物理 Q1 Mathematics Pub Date : 2025-12-01 DOI: 10.1103/d6y6-j48y
Ulysse Marquis

We introduce an ensemble of spatial networks built from the junctions of hindered-rotation chains, incorporating directional correlations between bonds, an aspect ignored in the standard network modeling paradigm. The emergent random networks support geodesics with a wandering exponent ξ=1/2, and a travel-time fluctuation exponent χ=0, consistent with the KPZ relation, yet violating the bound χ≥1/8 predicted in the Poissonian framework. Transverse deviations follow the Kolmogorov distribution, indicating similarities between Brownian bridge excursions and geodesics in a random medium with correlated edges orientations. These results reveal a new universality class of Euclidean first-passage percolation, where local orientational memory reshapes transport properties and challenges existing bounds for random spatial networks.

我们介绍了一个由阻碍旋转链的连接处构建的空间网络集合,结合了键之间的方向相关性,这是标准网络建模范式中忽略的一个方面。该随机网络支持漫游指数ξ=1/2和旅行时波动指数χ=0的测地线,符合KPZ关系,但违反泊松框架中预测的界χ≥1/8。横向偏差遵循Kolmogorov分布,表明布朗桥偏移与具有相关边取向的随机介质中的测地线相似。这些结果揭示了一种新的欧几里得第一通道渗透的普遍性,其中局部定向记忆重塑了传输性质,并挑战了随机空间网络的现有边界。
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引用次数: 0
From radiation dose to cellular dynamics: A discrete model for simulating cancer therapy. 从辐射剂量到细胞动力学:模拟癌症治疗的离散模型。
IF 2.4 3区 物理与天体物理 Q1 Mathematics Pub Date : 2025-12-01 DOI: 10.1103/fn8b-s7x3
Mirko Bagnarol, Gianluca Lattanzi, Jan Åström, Mikko Karttunen

Radiation therapy is one of the most common cancer treatments, and dose optimization and targeting of radiation are crucial since both cancerous and healthy cells are affected. Different mathematical and computational approaches have been developed for this task. The most common mathematical approach, dating back to the late 1970s, is the linear-quadratic (LQ) model for the survival probability given the radiation dose. Most simulation models consider tissue as a continuum rather than consisting of discrete cells. While reasonable for large-scale models (e.g., human organs), continuum approaches necessarily neglect cellular-scale effects, which may play a role in growth, morphology, and metastasis of tumors. Here we propose a method for modeling the effect of radiation on cells based on the mechanobiological CellSim3D simulation model for growth, division, and proliferation of cells. To model the effect of a radiation beam, we incorporate a Monte Carlo procedure into CellSim3D with the LQ model by introducing a survival probability at each beam delivery. Effective removal of dead cells by phagocytosis was also implemented. Systems with two types of cells were simulated: stiff slowly proliferating healthy cells and soft rapidly proliferating cancer cells. For model verification, the results were compared to prostate cancer (PC-3 cell line) data for different doses, and we found good agreement. In addition, we simulated proliferating systems and analyzed the probability density of the contact forces. We determined the state of the system with respect to the jamming transition and found very good agreement with experiments.

放射治疗是最常见的癌症治疗方法之一,由于癌细胞和健康细胞都会受到影响,因此剂量优化和辐射靶向至关重要。不同的数学和计算方法已经被开发出来。最常见的数学方法,可以追溯到20世纪70年代末,是给定辐射剂量的生存概率的线性二次(LQ)模型。大多数模拟模型认为组织是一个连续体,而不是由离散的细胞组成。虽然对于大尺度模型(如人体器官)是合理的,但连续体方法必然忽略了细胞尺度效应,而细胞尺度效应可能在肿瘤的生长、形态和转移中发挥作用。在这里,我们提出了一种基于细胞生长、分裂和增殖的机械生物学CellSim3D模拟模型来模拟辐射对细胞的影响的方法。为了模拟辐射光束的影响,我们将蒙特卡罗程序与LQ模型结合到CellSim3D中,通过引入每次光束发射的生存概率。通过吞噬作用有效地清除死细胞。模拟了两种类型细胞的系统:僵硬的缓慢增殖的健康细胞和柔软的快速增殖的癌细胞。为了验证模型,将结果与不同剂量的前列腺癌(PC-3细胞系)数据进行了比较,我们发现了很好的一致性。此外,我们模拟了扩散系统,并分析了接触力的概率密度。我们确定了系统在干扰过渡方面的状态,与实验结果非常吻合。
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引用次数: 0
Model for electrocurvature phase transitions in lipid bilayers driven by flip-flop asymmetry. 触发器不对称驱动的脂质双分子层电曲率相变模型。
IF 2.4 3区 物理与天体物理 Q1 Mathematics Pub Date : 2025-12-01 DOI: 10.1103/gjc6-tnp1
Adel Mohammed Djibaoui, Robert Bouzerar, Mohammed Guedda

The active transfer of phospholipids between membrane leaflets (flip-flop), mediated by (adenosine triphosphate) ATP-dependent enzymes such as flippases and floppases, is a key regulator of membrane asymmetry and curvature. However, the theoretical understanding of curvature generation driven by flip-flop under external perturbations remains incomplete. Here we present a mesoscopic thermodynamic model in which lipid asymmetry couples to membrane curvature via a Landau-type free energy, with curvature as the order parameter and transmembrane voltage as the control parameter. This framework predicts an electrically driven phase transition analogous to a ferroelectric transition. The model reproduces field-induced bistability, critical susceptibility divergence, and hysteresis, with numerical simulations revealing thickness-dependent curvature thresholds and robust curvature-memory effects. These results clarify how electric-field-driven lipid redistribution governs membrane shape and suggest strategies for voltage-controlled nanoscale memory and shape encoding.

磷脂在膜小叶之间的主动转移(flip-flop),由(三磷酸腺苷)atp依赖酶如flipppases和floppases介导,是膜不对称和弯曲的关键调节因子。然而,对于外部扰动下触发器驱动的曲率产生的理论认识仍然不完整。本文提出了一种介观热力学模型,其中脂质不对称性通过朗道型自由能与膜曲率耦合,以曲率为序参量,跨膜电压为控制参量。这个框架预测了类似铁电相变的电驱动相变。该模型再现了场致双稳性、临界磁化率散度和迟滞,通过数值模拟揭示了厚度相关的曲率阈值和稳健的曲率记忆效应。这些结果阐明了电场驱动的脂质再分配如何控制膜形状,并提出了电压控制纳米级记忆和形状编码的策略。
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引用次数: 0
Deterministic interrelation between elastic moduli in critically elastic materials. 临界弹性材料弹性模量之间的确定性相互关系。
IF 2.4 3区 物理与天体物理 Q1 Mathematics Pub Date : 2025-12-01 DOI: 10.1103/7tjt-m8s6
Hongryol Jeon, Mahdi Sadjadi, Varda F Hagh

Critically elastic materials-those that are rigid with a single state of self-stress-can be generated from parent systems with two states of self-stress by the removal of one of many constraints. We show that the elastic moduli of the resulting homogeneous and isotropic daughter systems are interrelated by a universal functional form parametrized by properties of the parent. In simulations of both spring networks and packings of soft spheres, judicious choice of parent systems and bond removal allows for the selection of a wide variety of moduli and Poisson's ratios in the critically elastic systems, providing a framework for versatile deterministic selection of mechanical properties.

临界弹性材料——那些具有单一自应力状态的刚性材料——可以通过去除许多约束中的一个,从具有两种自应力状态的母体系统中产生。我们证明了由此产生的齐次和各向同性子系统的弹性模量是由父系统的性质参数化的通用泛函形式相互关联的。在弹簧网络和软球填料的模拟中,明智地选择母系统和去除键可以在临界弹性系统中选择各种各样的模量和泊松比,为力学性能的通用确定性选择提供了一个框架。
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引用次数: 0
Stability of discrete-symmetry flocks: Sandwich state, traveling domains, and motility-induced pinning. 离散对称群的稳定性:夹心态、行域和运动诱导的钉住。
IF 2.4 3区 物理与天体物理 Q1 Mathematics Pub Date : 2025-12-01 DOI: 10.1103/1r19-ryx9
Swarnajit Chatterjee, Mintu Karmakar, Matthieu Mangeat, Heiko Rieger, Raja Paul

Polar flocks in discrete active systems are often assumed to be robust, yet recent studies reveal their fragility under both imposed and spontaneous fluctuations. Here, we revisit the four-state active Potts model and show that its globally ordered phase is metastable across a broad swath of parameter space. Small counterpropagating droplets disrupt the flocking phase by inducing a persistent sandwich state, where the droplet-induced opposite-polarity lane remains embedded within the original flock, particularly pronounced at low noise, influenced by spatial anisotropy. In contrast, small transversely propagating droplets, when introduced into the flock, can trigger complete phase reversal due to their alignment orthogonal to the dominant flow and their enhanced persistence. At low diffusion and strong self-propulsion, such transverse droplets also emerge spontaneously, fragmenting the flock into multiple traveling domains and giving rise to a short-range order (SRO) regime. We further identify a motility-induced pinning (MIP) transition in small diffusion and low-temperature regimes when particles of opposite polarity interact, flip their state, hop, and pin an interface. Our comprehensive phase diagrams, encompassing full reversal, sandwich coexistence, stripe bands, SRO, and MIP, delineate how thermal fluctuations, self-propulsion strength, and diffusion govern flock stability in discrete active matter systems.

离散有源系统中的极群通常被认为是鲁棒的,然而最近的研究表明它们在强加和自发波动下都是脆弱的。在这里,我们重新审视了四态活动波茨模型,并表明其全局有序相位在广泛的参数空间中是亚稳态的。小的反传播液滴通过诱导持续的夹心状态来破坏群集阶段,在这种状态下,液滴诱导的相反极性通道仍然嵌入在原始群集中,在低噪声下尤其明显,受空间各向异性的影响。相反,小的横向传播的液滴,当引入到群体中时,可以触发完全的相位反转,因为它们的方向与主导流正交,并且它们的持久性增强。在低扩散和强自推进时,这种横向液滴也会自发出现,将群集分散到多个行进域,并产生短程有序(SRO)状态。我们进一步确定了在小扩散和低温条件下,当极性相反的粒子相互作用,翻转它们的状态,跳跃并钉住界面时,运动诱导钉住(MIP)转变。我们的综合相图,包括完全反转、夹层共存、条纹带、SRO和MIP,描绘了热波动、自推进强度和扩散如何控制离散活性物质系统中的群稳定性。
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引用次数: 0
Synchronization detection using spatial ordinal partitions in networks. 在网络中使用空间有序分区进行同步检测。
IF 2.4 3区 物理与天体物理 Q1 Mathematics Pub Date : 2025-12-01 DOI: 10.1103/9chy-4db8
Zahra Shahriari, Shannon D Algar, David M Walker, Michael Small

We use a robust methodology that enables us to detect synchronous regions in networks of coupled dynamical systems and identify their collective behaviors. Our method employs ordinal patterns of spatial configuration of neighbor oscillators at each time point to ascertain whether or not neighboring nodes in a network are synchronized. We then use permutation entropy and forbidden sequence cardinality to classify collective behavior. We first demonstrate the effectiveness of our method on a time series of coupled identical logistic maps that are located on a ring. Our method not only confirms previous findings of collective behavior identification but also shows the borders of synchronous regions when oscillators of a network are partially synchronized. Then we apply our findings to a network of logistic maps with random connections to demonstrate the method's efficacy in situations where the network's spatiotemporal plots are not feasible.

我们使用一种强大的方法,使我们能够检测耦合动力系统网络中的同步区域,并识别它们的集体行为。我们的方法利用相邻振子在每个时间点的空间结构的有序模式来确定网络中相邻节点是否同步。然后,我们使用排列熵和禁止序列基数对集体行为进行分类。我们首先证明了我们的方法在位于环上的耦合相同逻辑映射的时间序列上的有效性。我们的方法不仅证实了先前的集体行为识别的发现,而且还显示了当网络的振荡器部分同步时同步区域的边界。然后,我们将我们的发现应用于随机连接的逻辑图网络,以证明该方法在网络的时空图不可行时的有效性。
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引用次数: 0
Random sequential adsorption of Pickering particles onto spherical emulsion droplet surfaces. 皮克林颗粒在球形乳化液液滴表面的随机顺序吸附。
IF 2.4 3区 物理与天体物理 Q1 Mathematics Pub Date : 2025-12-01 DOI: 10.1103/hkc7-5dfm
Yi Feng, Giulia Del Duca, Antonio Buffo, Elena Simone

Pickering emulsions are attracting growing attention as carriers of active ingredients or micronutrients in pharmaceutical and food applications, due to their high stability and low toxicity. The adsorption process of Pickering particles significantly affects emulsion properties and can be described using the random sequential adsorption (RSA) approach. While most studies focus on small, amorphous, spherical particles, the common use of elongated, crystalline, micron-sized particles in Pickering emulsions makes it necessary to consider the curvature and finite size of emulsion droplet surfaces to correctly understand and predict the interfacial adsorption behavior. The present study employs a Monte Carlo (MC) method to simulate the RSA process of both spherical and elongated micron-sized particles. Key factors such as particle polydispersity, emulsion droplet-particle size ratio, contact angle, and particle number are investigated. From the MC simulations, a new expression for the available surface function, ASF(ϕ), with coverage-dependent exponent is proposed. Based on this, generalized coverage evolution models are established using response surface methodology to relate RSA conditions to ASF(ϕ) parameters. For spherical particles, jamming coverage and desorption energy under various conditions are reported. For capsule-shaped particles, an aspect ratio of ε=2 is found to yield higher coverage and faster adsorption. The proposed ASF(ϕ) expression outperforms existing fixed-exponent expressions. The generalized coverage evolution models show good agreement with MC testing simulations. The mean absolute percentage errors are less than 2.63% for spherical particles and 6.58% for elongated ones in the validation cases.

酸洗乳剂由于其高稳定性和低毒性,在制药和食品中作为活性成分或微量营养素的载体越来越受到人们的关注。Pickering颗粒的吸附过程对乳状液的性质有显著影响,可以用随机顺序吸附(RSA)方法来描述。虽然大多数研究都集中在小的、无定形的球形颗粒上,但皮克林乳液中通常使用细长的、结晶的、微米大小的颗粒,因此有必要考虑乳液液滴表面的曲率和有限尺寸,以正确理解和预测界面吸附行为。本研究采用蒙特卡罗(MC)方法模拟了球形和细长微米粒子的RSA过程。研究了乳状液中颗粒的分散性、粒径比、接触角和颗粒数等关键因素。在MC模拟的基础上,提出了覆盖相关指数的可用曲面函数ASF(φ)的新表达式。在此基础上,利用响应面方法建立了广义覆盖演化模型,将RSA条件与ASF(ϕ)参数联系起来。报道了球形颗粒在不同条件下的干扰覆盖率和解吸能。对于胶囊状颗粒,宽高比ε=2可以获得更高的覆盖率和更快的吸附。所提出的ASF(ϕ)表达式优于现有的固定指数表达式。广义覆盖演化模型与MC测试仿真结果吻合较好。在验证案例中,球形粒子的平均绝对百分比误差小于2.63%,细长粒子的平均绝对百分比误差小于6.58%。
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引用次数: 0
Annealing approximation in master-node network model. 主节点网络模型的退火逼近。
IF 2.4 3区 物理与天体物理 Q1 Mathematics Pub Date : 2025-12-01 DOI: 10.1103/nrkx-myvk
M O Hase, Anderson A Ferreira, André C R Martins, Fernando F Ferreira

This paper investigates absorbing-state phase transitions in opinion dynamics through a master-node network model analyzed using annealing approximation. We develop a theoretical framework examining three fundamental regimes: systems converging to complete disagreement, complete consensus, or both states depending on initial conditions. The phase behavior is governed by two key chiral parameters: R measuring right-oriented influence and L measuring left-oriented influence in the network interactions. Our analysis reveals a rich phase diagram featuring both continuous and discontinuous transitions between disordered and ordered phases. The discontinuous transition emerges in systems with two absorbing states, where the final configuration depends critically on initial opinion distributions. The annealing approximation provides fundamental insights into how asymmetric social influences (chirality) shape collective opinion formation, acting as a symmetry-breaking element that drives the system toward polarization or consensus.

本文通过采用退火逼近分析的主节点网络模型来研究意见动态中的吸收态相变。我们开发了一个理论框架,检查三种基本制度:系统收敛到完全不同意,完全共识,或两者都取决于初始条件。相行为由两个关键的手性参数控制:R测量网络相互作用中的右向影响,L测量网络相互作用中的左向影响。我们的分析揭示了一个丰富的相图,在无序相和有序相之间具有连续和不连续的过渡。在具有两个吸收态的系统中出现了不连续的转换,其中最终配置严重依赖于初始意见分布。退火近似提供了对不对称社会影响(手性)如何塑造集体意见形成的基本见解,作为推动系统走向极化或共识的对称破坏因素。
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引用次数: 0
Probing the transition from classical to quantum radiation reaction in relativistic plasma. 探讨相对论等离子体中从经典到量子辐射反应的跃迁。
IF 2.4 3区 物理与天体物理 Q1 Mathematics Pub Date : 2025-12-01 DOI: 10.1103/y5vn-rpqf
Haidar Al-Naseri, Gert Brodin

We study the transition from classical radiation reaction, described by the Landau-Lifshitz model, to the quantum mechanical regime. The plasma is subject to a circularly polarized field where the self-consistent plasma current is the source of the electromagnetic field through Ampere's law. The radiation reaction implies wave energy loss, frequency up-conversion, and a modified distribution function. Increasing the value of the quantum χ-parameter, the quantum results gradually differ from the classical ones. Moreover, the deviation between models also depends on the plasma parameters, including density and temperature. We discuss the implications of our findings.

我们研究了由Landau-Lifshitz模型描述的经典辐射反应到量子力学机制的转变。等离子体受圆极化场影响,其中自一致的等离子体电流通过安培定律成为电磁场的来源。辐射反应包含波能损失、频率上转换和修正的分布函数。随着量子χ-参数值的增大,量子结果逐渐与经典结果不同。此外,模型之间的偏差还取决于等离子体参数,包括密度和温度。我们讨论了我们的发现的含义。
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引用次数: 0
Load-dependent power-law exponent in creep rupture of heterogeneous materials. 非均质材料蠕变断裂中随载荷变化的幂律指数。
IF 2.4 3区 物理与天体物理 Q1 Mathematics Pub Date : 2025-12-01 DOI: 10.1103/35tp-f364
Chloé Braux, Antoine Bérut, Loïc Vanel

Creep tests on heterogeneous materials under subcritical loading typically show a power-law decay in strain rate before failure, with the exponent often considered material dependent but independent of applied stress. By imposing successive small stress relaxations through a displacement feedback loop, we probe creep dynamics and show experimentally that this exponent varies with both applied load and loading direction. Simulations of a disordered fiber bundle model reproduce this load dependence, demonstrating that such models capture essential features of delayed rupture dynamics.

非均质材料在亚临界载荷下的蠕变试验通常显示出破坏前应变率呈幂律衰减,指数通常被认为与材料有关,但与外加应力无关。通过位移反馈回路施加连续的小应力松弛,我们探测蠕变动力学,并通过实验表明,该指数随施加载荷和加载方向而变化。对无序纤维束模型的模拟再现了这种载荷依赖性,表明这种模型捕捉到了延迟断裂动力学的基本特征。
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引用次数: 0
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