Lip lift is a versatile procedure to shorten the upper lip and improve the morphology and proportion of the lip. It is commonly performed as part of facial rejuvenation in Western patients, whereas in Asian countries, younger people tend to desire a lip lift because a shorter upper lip is considered more attractive. The lip lift carries a risk of an unfavorable aesthetic outcome when underlying skeletal deformities, such as maxillary protrusion and vertical excess, are not addressed, resulting in an undesirable degree of dental exposure. This article described our experience of integrating orthognathic surgery into subnasal lip lift surgery to harmonize the facial profile, highlighting the methods to achieve an ideal dental show with lip lift. Orthognathic surgery was first performed to correct the skeletal deformity. Subnasal lip lift with bull's horn-type skin excision and orbicularis oris muscle resection was then performed as a staged procedure. The degree of Cupid's bow elevation was determined by the amount of skin excised, and incisor show was determined by the amount of muscle resected. Seventeen patients underwent this combination approach, and the upper lip was successfully shortened with appropriate proportions and dental show. Overall, the aesthetic results were pleasing, with high patient satisfaction. Integrating orthognathic surgery into a lip lift aids in the enhancement of perioral aesthetics. Preexisting skeletal deformities need to be diagnosed before the lip lift and should be corrected when indicated.
{"title":"Integrating Orthognathic Surgery Into Lip Lift for Subnasal Aesthetics.","authors":"Yoshitsugu Hattori, Hirokazu Uda, Makoto Omori, Takanobu Mashiko, Yasushi Sugawara","doi":"10.1097/GOX.0000000000007230","DOIUrl":"10.1097/GOX.0000000000007230","url":null,"abstract":"<p><p>Lip lift is a versatile procedure to shorten the upper lip and improve the morphology and proportion of the lip. It is commonly performed as part of facial rejuvenation in Western patients, whereas in Asian countries, younger people tend to desire a lip lift because a shorter upper lip is considered more attractive. The lip lift carries a risk of an unfavorable aesthetic outcome when underlying skeletal deformities, such as maxillary protrusion and vertical excess, are not addressed, resulting in an undesirable degree of dental exposure. This article described our experience of integrating orthognathic surgery into subnasal lip lift surgery to harmonize the facial profile, highlighting the methods to achieve an ideal dental show with lip lift. Orthognathic surgery was first performed to correct the skeletal deformity. Subnasal lip lift with bull's horn-type skin excision and orbicularis oris muscle resection was then performed as a staged procedure. The degree of Cupid's bow elevation was determined by the amount of skin excised, and incisor show was determined by the amount of muscle resected. Seventeen patients underwent this combination approach, and the upper lip was successfully shortened with appropriate proportions and dental show. Overall, the aesthetic results were pleasing, with high patient satisfaction. Integrating orthognathic surgery into a lip lift aids in the enhancement of perioral aesthetics. Preexisting skeletal deformities need to be diagnosed before the lip lift and should be corrected when indicated.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 12","pages":"e7230"},"PeriodicalIF":1.8,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12688944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145724941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Source-grounded artificial intelligence (AI) models have emerged in the public domain and represent a powerful tool for content creation. These models allow users to "ground" the language model in user-input sources and convert text to audio. Although plastic and reconstructive surgery has traditionally relied on textbook sources for trainee education, we demonstrate the potential to migrate information to audio sources. We created podcasts using source-grounded AI technology based on selected chapters of Grabb and Smith's Plastic Surgery. Generated audio was created using NotebookLM and featured a conversation between 2 AI "broadcasters." Surveys were distributed to assess trainee feedback on AI-generated podcasts compared with the source material. Eight source-grounded AI podcasts were created on topics including wound healing, breast reconstruction, lower extremity reconstruction, and aesthetic principles. Generated audio had a mean length of 14.3 ± 0.2 minutes. Generated podcasts had excellent accuracy with no extraneous insertion of information. Weaknesses of AI-generated podcasts included under- or overemphasis on topics that were emphasized in the source. Survey participants (n = 10) on average spent 14.7 ± 4.7 minutes with the podcast and 34.0 ± 13.9 minutes with the book chapter. Participants preferred a mixed-media approach (90%) over text (0%) or audio alone (10%) for learning the specified material. We demonstrate the potential for source-grounded AI models to aid in the creation of audio-based plastic surgery educational content with high accuracy. This technology can translate plastic surgery literature into audible content to diversify the media available to trainees and practitioners.
基于源的人工智能(AI)模型已经出现在公共领域,并代表了内容创作的强大工具。这些模型允许用户在用户输入源中“接地”语言模型,并将文本转换为音频。尽管整形和重建手术传统上依赖于教科书来源的培训生教育,但我们证明了将信息迁移到音频来源的潜力。我们根据《Grabb and Smith’s Plastic Surgery》的部分章节,使用人工智能技术创建了播客。生成的音频是使用NotebookLM创建的,并以两个AI“播音员”之间的对话为特色。分发了调查问卷,以评估实习生对人工智能生成的播客的反馈,并将其与原始材料进行比较。8个人工智能播客的主题包括伤口愈合、乳房重建、下肢重建和美学原则。生成的音频平均长度为14.3±0.2分钟。生成的播客具有极好的准确性,没有多余的信息插入。人工智能生成的播客的缺点包括对源中强调的主题的强调不足或过度强调。调查参与者(n = 10)平均花14.7±4.7分钟在播客上,34.0±13.9分钟在书本章节上。在学习指定材料时,参与者更喜欢混合媒体方法(90%),而不是文本(0%)或单独的音频(10%)。我们展示了基于源的人工智能模型的潜力,以帮助以高精度创建基于音频的整形外科教育内容。这项技术可以将整形外科文献翻译成可听的内容,使受训者和从业者可以使用的媒体多样化。
{"title":"Source-grounded Artificial Intelligence-Driven Transfer of Plastic Surgery Textbooks to Podcasts: Creation of Content and Trainee Satisfaction.","authors":"Iulianna Taritsa, Parul Rai, Anitesh Bajaj, Hannah Soltani, Arun K Gosain","doi":"10.1097/GOX.0000000000007299","DOIUrl":"10.1097/GOX.0000000000007299","url":null,"abstract":"<p><p>Source-grounded artificial intelligence (AI) models have emerged in the public domain and represent a powerful tool for content creation. These models allow users to \"ground\" the language model in user-input sources and convert text to audio. Although plastic and reconstructive surgery has traditionally relied on textbook sources for trainee education, we demonstrate the potential to migrate information to audio sources. We created podcasts using source-grounded AI technology based on selected chapters of <i>Grabb and Smith's Plastic Surgery</i>. Generated audio was created using NotebookLM and featured a conversation between 2 AI \"broadcasters.\" Surveys were distributed to assess trainee feedback on AI-generated podcasts compared with the source material. Eight source-grounded AI podcasts were created on topics including wound healing, breast reconstruction, lower extremity reconstruction, and aesthetic principles. Generated audio had a mean length of 14.3 ± 0.2 minutes. Generated podcasts had excellent accuracy with no extraneous insertion of information. Weaknesses of AI-generated podcasts included under- or overemphasis on topics that were emphasized in the source. Survey participants (n = 10) on average spent 14.7 ± 4.7 minutes with the podcast and 34.0 ± 13.9 minutes with the book chapter. Participants preferred a mixed-media approach (90%) over text (0%) or audio alone (10%) for learning the specified material. We demonstrate the potential for source-grounded AI models to aid in the creation of audio-based plastic surgery educational content with high accuracy. This technology can translate plastic surgery literature into audible content to diversify the media available to trainees and practitioners.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 12","pages":"e7299"},"PeriodicalIF":1.8,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12688858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145725065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09eCollection Date: 2025-12-01DOI: 10.1097/GOX.0000000000007311
Jaimie J Lee, Yi-Fu Chen, Gregory Arbour, Alan M Nichol, Raymond T Ng, Kathryn V Isaac
Background: Postmastectomy radiotherapy (PMRT) in the context of immediate implant-based breast reconstruction (IIBBR) is associated with long-term morbidity. The likelihood of PMRT may influence the type and timing of breast reconstruction chosen in the preoperative setting. This study aimed to validate a machine learning (ML) model for predicting the probability of PMRT recommendations in IIBBR patients, in accordance with the transparent reporting of studies on prediction models for individual prognosis or diagnosis guidelines.
Methods: The study cohort comprised 224 breast cancer patients who underwent mastectomy with IIBBR from January 2021 to December 2022. Data were collected on 12 patient characteristics identified as predictive in our ML model. Preoperative characteristics were recorded from clinical history, physical examination, diagnostic imaging, and pathology reports.
Results: Of the 224 patients, 37% (n = 84) were recommended PMRT. Our ML model demonstrated high predictive performance, with an area under the receiver operating characteristic curve score of 0.80 (0.74-0.86). The variables most predictive of PMRT recommendation included the size of suspicious lymph nodes, the presence of carcinoma in axillary lymph node biopsies, tumor size, and the use of ultrasound as the initial diagnostic modality.
Conclusions: An ML model for predicting PMRT recommendations following IIBBR was validated. This prediction model may be helpful in the preoperative clinical setting to inform the discussion of reconstructive options.
{"title":"Validation of a Machine Learning Model for Predicting Postmastectomy Radiotherapy Recommendation Following Immediate Breast Reconstruction.","authors":"Jaimie J Lee, Yi-Fu Chen, Gregory Arbour, Alan M Nichol, Raymond T Ng, Kathryn V Isaac","doi":"10.1097/GOX.0000000000007311","DOIUrl":"10.1097/GOX.0000000000007311","url":null,"abstract":"<p><strong>Background: </strong>Postmastectomy radiotherapy (PMRT) in the context of immediate implant-based breast reconstruction (IIBBR) is associated with long-term morbidity. The likelihood of PMRT may influence the type and timing of breast reconstruction chosen in the preoperative setting. This study aimed to validate a machine learning (ML) model for predicting the probability of PMRT recommendations in IIBBR patients, in accordance with the transparent reporting of studies on prediction models for individual prognosis or diagnosis guidelines.</p><p><strong>Methods: </strong>The study cohort comprised 224 breast cancer patients who underwent mastectomy with IIBBR from January 2021 to December 2022. Data were collected on 12 patient characteristics identified as predictive in our ML model. Preoperative characteristics were recorded from clinical history, physical examination, diagnostic imaging, and pathology reports.</p><p><strong>Results: </strong>Of the 224 patients, 37% (n = 84) were recommended PMRT. Our ML model demonstrated high predictive performance, with an area under the receiver operating characteristic curve score of 0.80 (0.74-0.86). The variables most predictive of PMRT recommendation included the size of suspicious lymph nodes, the presence of carcinoma in axillary lymph node biopsies, tumor size, and the use of ultrasound as the initial diagnostic modality.</p><p><strong>Conclusions: </strong>An ML model for predicting PMRT recommendations following IIBBR was validated. This prediction model may be helpful in the preoperative clinical setting to inform the discussion of reconstructive options.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 12","pages":"e7311"},"PeriodicalIF":1.8,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12689033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145725051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09eCollection Date: 2025-12-01DOI: 10.1097/GOX.0000000000007332
Sumeet S Teotia, Thomas C Troia, Lauren J Kim, Nicholas T Haddock
Background: Patients who have undergone abdominoplasty face limited options for microsurgical breast reconstruction, as the deep inferior epigastric perforator flap is often unavailable. This study compared lumbar artery perforator (LAP) and profunda artery perforator (PAP) flaps for microsurgical breast reconstruction in patients with prior abdominoplasty.
Methods: A retrospective chart review was conducted on all patients who underwent microsurgical breast reconstruction between January 2011 and May 2023. Data analyzed included demographics, comorbidities, reconstruction type, complications, and patient-reported outcomes measured by BREAST-Q surveys. Statistical analysis used the Pearson χ2 test and independent samples t test.
Results: A total of 264 patients underwent microsurgical breast reconstruction, with 39 having a history of abdominoplasty. Patients with prior abdominoplasty were older (54.4 ± 7.8 versus 50.5 ± 9.1 y, P = 0.012) and had a significantly higher body mass index (28.8 ± 4.4 versus 25.3 ± 4.2 kg/m2, P < 0.001). Hypertension (30.8% versus 15.6%, P = 0.023) and diabetes (12.8% versus 4.0%, P = 0.024) were also more common in the abdominoplasty group. Among abdominoplasty patients, LAP flaps were more often undergone (66.7% versus 26.2%, P < 0.001). LAP flap recipients reported significantly higher BREAST-Q scores compared with PAP flap patients (all P < 0.001).
Conclusions: The LAP flap emerges as a superior option for microsurgical breast reconstruction in patients with prior abdominoplasty, providing higher patient satisfaction compared with PAP flaps. This study highlights the necessity of personalized, adaptable surgical approaches in microsurgical breast reconstruction, emphasizing patient-specific anatomical and historical considerations to optimize outcomes.
{"title":"Microsurgical Breast Reconstruction Options After Abdominoplasty: Lumbar Artery Perforator Versus Profunda Artery Perforator.","authors":"Sumeet S Teotia, Thomas C Troia, Lauren J Kim, Nicholas T Haddock","doi":"10.1097/GOX.0000000000007332","DOIUrl":"10.1097/GOX.0000000000007332","url":null,"abstract":"<p><strong>Background: </strong>Patients who have undergone abdominoplasty face limited options for microsurgical breast reconstruction, as the deep inferior epigastric perforator flap is often unavailable. This study compared lumbar artery perforator (LAP) and profunda artery perforator (PAP) flaps for microsurgical breast reconstruction in patients with prior abdominoplasty.</p><p><strong>Methods: </strong>A retrospective chart review was conducted on all patients who underwent microsurgical breast reconstruction between January 2011 and May 2023. Data analyzed included demographics, comorbidities, reconstruction type, complications, and patient-reported outcomes measured by BREAST-Q surveys. Statistical analysis used the Pearson χ<sup>2</sup> test and independent samples <i>t</i> test.</p><p><strong>Results: </strong>A total of 264 patients underwent microsurgical breast reconstruction, with 39 having a history of abdominoplasty. Patients with prior abdominoplasty were older (54.4 ± 7.8 versus 50.5 ± 9.1 y, <i>P</i> = 0.012) and had a significantly higher body mass index (28.8 ± 4.4 versus 25.3 ± 4.2 kg/m<sup>2</sup>, <i>P</i> < 0.001). Hypertension (30.8% versus 15.6%, <i>P</i> = 0.023) and diabetes (12.8% versus 4.0%, <i>P</i> = 0.024) were also more common in the abdominoplasty group. Among abdominoplasty patients, LAP flaps were more often undergone (66.7% versus 26.2%, <i>P</i> < 0.001). LAP flap recipients reported significantly higher BREAST-Q scores compared with PAP flap patients (all <i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>The LAP flap emerges as a superior option for microsurgical breast reconstruction in patients with prior abdominoplasty, providing higher patient satisfaction compared with PAP flaps. This study highlights the necessity of personalized, adaptable surgical approaches in microsurgical breast reconstruction, emphasizing patient-specific anatomical and historical considerations to optimize outcomes.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 12","pages":"e7332"},"PeriodicalIF":1.8,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12689011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145724934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09eCollection Date: 2025-12-01DOI: 10.1097/GOX.0000000000007293
Pablo Pfister, Julia Stoffel, Marie Perrin, Christian Appenzeller-Herzog, Florian S Halbeisen, Lukas Seifert, Daniel Bodmer, Laurent Muller, Maximilian Burger, Rene D Largo, Tarek Ismail, Elisabeth A Kappos
Background: Patient-reported outcome measures (PROMs) have become an integral part of outcome evaluation in reconstructive microsurgery. This study explored the usage of PROMs in microsurgical oncological head and neck reconstruction across surgical specialties and geographic regions.
Methods: A systematic literature search was conducted in Embase, MEDLINE, and Web of Science to identify studies reporting on adult patients undergoing oncological head and neck free flap reconstruction. Data extracted included PROM tools used, study demographics, surgical disciplines involved, procedural details, and outcomes.
Results: Of 5015 screened studies, 354 (n = 30,369 patients) met the inclusion criteria. A total of 94 PROM tools were identified. The most frequently used were the University of Washington Quality of Life Questionnaire (34.75%), nonvalidated tools (25.99%), and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire - Head and Neck Module 35 (22.32%). Donor site-specific PROMs were infrequently used (22%), though more frequently used when plastic and reconstructive surgeons were involved (31.11% versus 15.53%, P = 0.019). PROM selection varied significantly by specialty and geographic location, and only 20% of studies were interdisciplinary.
Conclusions: Substantial heterogeneity exists in the use of PROMs in head and neck reconstruction, with variations driven by specialty and region. This lack of standardization hinders meaningful cross-study comparisons and the development of robust quality benchmarks. A unified, validated PROM framework is urgently needed to support international evidence-based practice. Future efforts should prioritize interdisciplinary collaboration and incorporate donor-site evaluation to comprehensively assess outcomes in oncological head and neck reconstruction.
背景:患者报告的结果测量(PROMs)已成为重建显微手术结果评估的一个组成部分。本研究探讨了PROMs在显微外科肿瘤头颈部重建中的应用,跨越外科专业和地理区域。方法:系统检索Embase、MEDLINE和Web of Science中有关成人肿瘤头颈部游离皮瓣重建的文献。提取的数据包括使用的PROM工具、研究人口统计学、涉及的手术学科、手术细节和结果。结果:在5015项筛选研究中,354例(n = 30,369例)符合纳入标准。总共确定了94种PROM工具。最常用的是华盛顿大学生活质量问卷(34.75%),未经验证的工具(25.99%)和欧洲癌症研究和治疗组织生活质量问卷-头颈模块35(22.32%)。供体部位特异性PROMs很少使用(22%),但在涉及整形和重建手术时使用频率更高(31.11%对15.53%,P = 0.019)。毕业舞会的选择因专业和地理位置的不同而有很大差异,只有20%的研究是跨学科的。结论:PROMs在头颈部重建中的应用存在很大的异质性,其差异受专业和地区的驱动。这种标准化的缺乏阻碍了有意义的交叉研究比较和健全的质量基准的发展。迫切需要一个统一的、经过验证的PROM框架来支持国际循证实践。未来的努力应优先考虑跨学科合作,并纳入供体-部位评估,以全面评估肿瘤头颈部重建的结果。
{"title":"Patient-reported Outcome Measures in Head and Neck Reconstruction: A Systematic Review Across Disciplines and Geographical Locations.","authors":"Pablo Pfister, Julia Stoffel, Marie Perrin, Christian Appenzeller-Herzog, Florian S Halbeisen, Lukas Seifert, Daniel Bodmer, Laurent Muller, Maximilian Burger, Rene D Largo, Tarek Ismail, Elisabeth A Kappos","doi":"10.1097/GOX.0000000000007293","DOIUrl":"10.1097/GOX.0000000000007293","url":null,"abstract":"<p><strong>Background: </strong>Patient-reported outcome measures (PROMs) have become an integral part of outcome evaluation in reconstructive microsurgery. This study explored the usage of PROMs in microsurgical oncological head and neck reconstruction across surgical specialties and geographic regions.</p><p><strong>Methods: </strong>A systematic literature search was conducted in Embase, MEDLINE, and Web of Science to identify studies reporting on adult patients undergoing oncological head and neck free flap reconstruction. Data extracted included PROM tools used, study demographics, surgical disciplines involved, procedural details, and outcomes.</p><p><strong>Results: </strong>Of 5015 screened studies, 354 (n = 30,369 patients) met the inclusion criteria. A total of 94 PROM tools were identified. The most frequently used were the University of Washington Quality of Life Questionnaire (34.75%), nonvalidated tools (25.99%), and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire - Head and Neck Module 35 (22.32%). Donor site-specific PROMs were infrequently used (22%), though more frequently used when plastic and reconstructive surgeons were involved (31.11% versus 15.53%, <i>P</i> = 0.019). PROM selection varied significantly by specialty and geographic location, and only 20% of studies were interdisciplinary.</p><p><strong>Conclusions: </strong>Substantial heterogeneity exists in the use of PROMs in head and neck reconstruction, with variations driven by specialty and region. This lack of standardization hinders meaningful cross-study comparisons and the development of robust quality benchmarks. A unified, validated PROM framework is urgently needed to support international evidence-based practice. Future efforts should prioritize interdisciplinary collaboration and incorporate donor-site evaluation to comprehensively assess outcomes in oncological head and neck reconstruction.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 12","pages":"e7293"},"PeriodicalIF":1.8,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12688922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145725020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09eCollection Date: 2025-12-01DOI: 10.1097/GOX.0000000000007331
Christy O T Kwok, Shreya Luthra, Kimberly DeVries, Esta Bovill, Nancy Yvonne Van Laeken, Sheina Macadam, Peter Lennox, Christopher Doherty, Kathryn V Isaac
Background: Delivery of immediate breast reconstruction (IBR) was severely restricted during the coronavirus disease 2019 (COVID-19) pandemic, with irreversible consequences for breast cancer survivors. This study aimed to determine the pandemic's effect on the provision of IBR services, quality of care delivered, and reconstructive outcomes.
Methods: For this multi-institutional, retrospective cohort study, data were obtained from all IBR cases during the study periods defined as "pre-COVID-19" (October 1, 2018, to March 14, 2020) and "COVID-19" (March 15, 2020, to October 31, 2021). Patient demographics, reconstructive strategy types, and oncological and surgical characteristics were analyzed. Safety and quality outcomes, including readmission, infection, seroma, mastectomy flap necrosis, and wait times were recorded.
Results: A cohort of 525 patients was included in this study. Patient and tumor characteristics were similar between the 2 study periods. There was a significantly lower odds of undergoing a single-stage alloplastic surgery (odds ratio [OR] = 0.40, 95% confidence interval [CI] = 0.17-0.94, P = 0.0365) or autologous immediate reconstruction with a deep inferior epigastric perforator (DIEP) flap (OR = 0.42, 95% CI = 0.21-0.85, P = 0.015) during the COVID-19 era, with a reciprocal 53% higher odds of 2-stage alloplastic surgery (OR = 1.53, 95% CI = 1.03-2.27, P = 0.0359) during that time. Median wait time from first-stage to second-stage reconstruction was significantly shorter during COVID-19 (P = 0.0017). There were no differences in safety outcomes between the periods.
Conclusions: Reconstructive strategies differed during the COVID-19 era of resource limitations with more 2-stage alloplastic procedures and fewer single-stage alloplastic and autologous immediate DIEP flap procedures.
背景:在2019冠状病毒病(COVID-19)大流行期间,立即乳房重建(IBR)的实施受到严重限制,对乳腺癌幸存者造成了不可逆转的后果。本研究旨在确定大流行对IBR服务的提供、提供的护理质量和重建结果的影响。方法:在这项多机构、回顾性队列研究中,数据来自研究期间的所有IBR病例,研究期间定义为“COVID-19前期”(2018年10月1日至2020年3月14日)和“COVID-19”(2020年3月15日至2021年10月31日)。分析患者人口统计学、重建策略类型、肿瘤和外科特征。记录安全性和质量结果,包括再入院、感染、血清肿、乳房切除术皮瓣坏死和等待时间。结果:本研究纳入了525例患者。两个研究期间患者及肿瘤特征相似。在COVID-19时期,接受单期同种异体整形手术的几率(比值比[OR] = 0.40, 95%可信区间[CI] = 0.17-0.94, P = 0.0365)或采用上腹部深下穿支(DIEP)皮瓣进行自体立即重建的几率(OR = 0.42, 95% CI = 0.21-0.85, P = 0.015)显著降低,而接受两期同种异体整形手术的几率(OR = 1.53, 95% CI = 1.03-2.27, P = 0.0359)的几率则高出53%。COVID-19患者从第一阶段到第二阶段重建的中位等待时间显著缩短(P = 0.0017)。两个时期的安全性结果没有差异。结论:在资源有限的COVID-19时代,重建策略不同,更多的是2期同种异体移植手术,更少的是单期同种异体移植和自体立即DIEP皮瓣手术。
{"title":"Effect of Coronavirus Disease 2019 Pandemic on Delivery of Breast Reconstructive Services and Outcomes.","authors":"Christy O T Kwok, Shreya Luthra, Kimberly DeVries, Esta Bovill, Nancy Yvonne Van Laeken, Sheina Macadam, Peter Lennox, Christopher Doherty, Kathryn V Isaac","doi":"10.1097/GOX.0000000000007331","DOIUrl":"10.1097/GOX.0000000000007331","url":null,"abstract":"<p><strong>Background: </strong>Delivery of immediate breast reconstruction (IBR) was severely restricted during the coronavirus disease 2019 (COVID-19) pandemic, with irreversible consequences for breast cancer survivors. This study aimed to determine the pandemic's effect on the provision of IBR services, quality of care delivered, and reconstructive outcomes.</p><p><strong>Methods: </strong>For this multi-institutional, retrospective cohort study, data were obtained from all IBR cases during the study periods defined as \"pre-COVID-19\" (October 1, 2018, to March 14, 2020) and \"COVID-19\" (March 15, 2020, to October 31, 2021). Patient demographics, reconstructive strategy types, and oncological and surgical characteristics were analyzed. Safety and quality outcomes, including readmission, infection, seroma, mastectomy flap necrosis, and wait times were recorded.</p><p><strong>Results: </strong>A cohort of 525 patients was included in this study. Patient and tumor characteristics were similar between the 2 study periods. There was a significantly lower odds of undergoing a single-stage alloplastic surgery (odds ratio [OR] = 0.40, 95% confidence interval [CI] = 0.17-0.94, <i>P</i> = 0.0365) or autologous immediate reconstruction with a deep inferior epigastric perforator (DIEP) flap (OR = 0.42, 95% CI = 0.21-0.85, <i>P</i> = 0.015) during the COVID-19 era, with a reciprocal 53% higher odds of 2-stage alloplastic surgery (OR = 1.53, 95% CI = 1.03-2.27, <i>P</i> = 0.0359) during that time. Median wait time from first-stage to second-stage reconstruction was significantly shorter during COVID-19 (<i>P</i> = 0.0017). There were no differences in safety outcomes between the periods.</p><p><strong>Conclusions: </strong>Reconstructive strategies differed during the COVID-19 era of resource limitations with more 2-stage alloplastic procedures and fewer single-stage alloplastic and autologous immediate DIEP flap procedures.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 12","pages":"e7331"},"PeriodicalIF":1.8,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12688998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145724610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09eCollection Date: 2025-12-01DOI: 10.1097/GOX.0000000000007318
Jee Soo Kook, Jovian Wan, Kyung Tae Bae, Kyu-Ho Yi
Melasma poses considerable challenges in dermatologic management, particularly due to variable treatment responses and frequent recurrence following conventional interventions. We describe ethosome photothermal therapy (ETHOSOMEPTT, N-Finders Co., Ltd, Korea), an innovative 5-layer nanosystem that integrates transdermal delivery technology with targeted laser energy. The platform incorporates ethosomes, phospholipid vesicles containing ethanol, with plasmonic gold and platinum nanoparticles to provide dual therapeutic mechanisms: enhanced drug penetration and controlled hyperthermia. Upon activation by specific laser wavelengths, this system generates localized heat while facilitating the delivery of active ingredients to deeper tissue layers relative to conventional topical treatments. A clinical example demonstrates its utility: a 42-year-old woman with persistent malar melasma spanning 6 years, who had undergone treatment with hydroquinone, oral tranexamic acid, and neodymium-doped yttrium aluminum garnet laser with insufficient improvement, demonstrated a 68% reduction in Modified Melasma Area and Severity Index after 12 treatment sessions. Treatment was well tolerated, with transient erythema as the primary side effect. The mechanism underlying ethosome photothermal therapy encompasses ethanol-mediated enhancement of stratum corneum permeability, targeted delivery via plasmonic nanoparticles, and controlled thermal effects on tissue structure. This methodology represents a potential advancement in melasma management, particularly for cases demonstrating limited response to conventional therapies.
{"title":"Ethosome (ETHOSOMEPTT) Photothermal Therapy with Nd:YAG Laser (Pastelle Pro): A Novel Nanotechnology Approach for Treatment-resistant Melasma.","authors":"Jee Soo Kook, Jovian Wan, Kyung Tae Bae, Kyu-Ho Yi","doi":"10.1097/GOX.0000000000007318","DOIUrl":"10.1097/GOX.0000000000007318","url":null,"abstract":"<p><p>Melasma poses considerable challenges in dermatologic management, particularly due to variable treatment responses and frequent recurrence following conventional interventions. We describe ethosome photothermal therapy (ETHOSOMEPTT, N-Finders Co., Ltd, Korea), an innovative 5-layer nanosystem that integrates transdermal delivery technology with targeted laser energy. The platform incorporates ethosomes, phospholipid vesicles containing ethanol, with plasmonic gold and platinum nanoparticles to provide dual therapeutic mechanisms: enhanced drug penetration and controlled hyperthermia. Upon activation by specific laser wavelengths, this system generates localized heat while facilitating the delivery of active ingredients to deeper tissue layers relative to conventional topical treatments. A clinical example demonstrates its utility: a 42-year-old woman with persistent malar melasma spanning 6 years, who had undergone treatment with hydroquinone, oral tranexamic acid, and neodymium-doped yttrium aluminum garnet laser with insufficient improvement, demonstrated a 68% reduction in Modified Melasma Area and Severity Index after 12 treatment sessions. Treatment was well tolerated, with transient erythema as the primary side effect. The mechanism underlying ethosome photothermal therapy encompasses ethanol-mediated enhancement of stratum corneum permeability, targeted delivery via plasmonic nanoparticles, and controlled thermal effects on tissue structure. This methodology represents a potential advancement in melasma management, particularly for cases demonstrating limited response to conventional therapies.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 12","pages":"e7318"},"PeriodicalIF":1.8,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12688895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145724654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09eCollection Date: 2025-12-01DOI: 10.1097/GOX.0000000000007323
Mohammadhossein Hesamirostami, Sami Hesamirostami, Sanli Hesamirostami
One of the most important and challenging decisions in reduction mammaplasty and mastopexy is the choice of incision. Although an existing algorithm considers the sternal notch-nipple distance, patient age, and skin quality to guide selection, it remains incomplete. The superior breast border-inframammary fold distance provides a more accurate assessment of the actual amount of skin and tissue. By analyzing this measurement-along with its components and the patient's skin quality-we can determine the optimal incision type using the mathematics of distances and breast geometry. In brief, a superior breast border-inframammary fold distance of up to approximately 32 cm is generally suitable for a vertical scar mammaplasty.
{"title":"Innovative Preoperative Mathematical Suggestion for Vertical Incision in Mammaplasty.","authors":"Mohammadhossein Hesamirostami, Sami Hesamirostami, Sanli Hesamirostami","doi":"10.1097/GOX.0000000000007323","DOIUrl":"10.1097/GOX.0000000000007323","url":null,"abstract":"<p><p>One of the most important and challenging decisions in reduction mammaplasty and mastopexy is the choice of incision. Although an existing algorithm considers the sternal notch-nipple distance, patient age, and skin quality to guide selection, it remains incomplete. The superior breast border-inframammary fold distance provides a more accurate assessment of the actual amount of skin and tissue. By analyzing this measurement-along with its components and the patient's skin quality-we can determine the optimal incision type using the mathematics of distances and breast geometry. In brief, a superior breast border-inframammary fold distance of up to approximately 32 cm is generally suitable for a vertical scar mammaplasty.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 12","pages":"e7323"},"PeriodicalIF":1.8,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12689085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145724775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-08eCollection Date: 2025-12-01DOI: 10.1097/GOX.0000000000007330
Jason Zhang, Narainsai K Reddy, Gabrielle C Rodriguez, Kristian Nenchev, Nikhil Sriram, Morgan Gamble, Muhammad T Hassan, Reyna A Patel, Parul Rai, Hannah Soltani, Arun K Gosain
Background: Analyzing characteristics of national leaders in surgery can provide insight into the factors that contribute to their success.
Methods: The names of the 2024 executive board and past presidents were collected from national surgical subspecialty organizations. A cross-sectional analysis of training and leadership backgrounds was conducted from information gathered online. Logistic regression was used to analyze predictors for executive positions.
Results: A total of 871 leaders from 48 organizations were characterized, including 66 plastic surgeons. Most (84.5%) leaders completed a subspecialty-specific fellowship and had a mean of 3.6 institutional positions. The number of chief/chair positions (odds ratio [95% confidence interval] = 1.55 [1.31-1.84]) and editor positions (1.11 [1.02-1.23]) were associated with increased odds of being a national vice president/president, whereas completing multiple fellowships was associated with decreased odds (odds ratio [95% confidence interval] = 0.56 [0.35-0.88]). Plastic surgery leaders had higher rates of no fellowship training (22.7% versus 5.5%) and a lower average number of industry positions (0.1 versus 0.4) compared with those in other fields. Compared with presidents in other specialties, plastic surgery presidents had lower rates of subspecialty-specific fellowship training (72.2% versus 84.9%).
Conclusions: Experience leading at the institutional level is correlated with national surgical leadership. Our findings may help guide young plastic surgeons hoping to become involved at the national level.
{"title":"Comparing Predictors for Leadership in Surgical Subspecialty National Organizations.","authors":"Jason Zhang, Narainsai K Reddy, Gabrielle C Rodriguez, Kristian Nenchev, Nikhil Sriram, Morgan Gamble, Muhammad T Hassan, Reyna A Patel, Parul Rai, Hannah Soltani, Arun K Gosain","doi":"10.1097/GOX.0000000000007330","DOIUrl":"10.1097/GOX.0000000000007330","url":null,"abstract":"<p><strong>Background: </strong>Analyzing characteristics of national leaders in surgery can provide insight into the factors that contribute to their success.</p><p><strong>Methods: </strong>The names of the 2024 executive board and past presidents were collected from national surgical subspecialty organizations. A cross-sectional analysis of training and leadership backgrounds was conducted from information gathered online. Logistic regression was used to analyze predictors for executive positions.</p><p><strong>Results: </strong>A total of 871 leaders from 48 organizations were characterized, including 66 plastic surgeons. Most (84.5%) leaders completed a subspecialty-specific fellowship and had a mean of 3.6 institutional positions. The number of chief/chair positions (odds ratio [95% confidence interval] = 1.55 [1.31-1.84]) and editor positions (1.11 [1.02-1.23]) were associated with increased odds of being a national vice president/president, whereas completing multiple fellowships was associated with decreased odds (odds ratio [95% confidence interval] = 0.56 [0.35-0.88]). Plastic surgery leaders had higher rates of no fellowship training (22.7% versus 5.5%) and a lower average number of industry positions (0.1 versus 0.4) compared with those in other fields. Compared with presidents in other specialties, plastic surgery presidents had lower rates of subspecialty-specific fellowship training (72.2% versus 84.9%).</p><p><strong>Conclusions: </strong>Experience leading at the institutional level is correlated with national surgical leadership. Our findings may help guide young plastic surgeons hoping to become involved at the national level.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 12","pages":"e7330"},"PeriodicalIF":1.8,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12685402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145715307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-08eCollection Date: 2025-12-01DOI: 10.1097/GOX.0000000000007346
Mustafa Tezcan
Preoperative markings are essential in breast reduction surgery, yet conventional hand-drawn methods may be prone to inaccuracies, particularly in patients with large or ptotic breasts. This study aimed to introduce and evaluate a standardized preoperative drawing method using temporary tattoos based on 3-dimensional (3D) breast modeling. Three-dimensional breast models were created using Blender 3D software, incorporating various base diameters and nipple-areola complex widths. The models were flattened into 2D templates and transferred to skin using temporary tattoos. A 5-step standardized drawing protocol was designed and applied to the simulated model. Ratios between breast base circumference and nipple-areola complex diameter were analyzed to guide excision planning. The 2D templates preserved key proportional relationships derived from 3D analysis. The use of temporary tattoos reduced variability in markings caused by tissue elasticity and human error. Tattoos remained intact for several days, enabling surgeons to perform and verify markings ahead of surgery without disruption to daily activities. Temporary tattoos based on 3D modeling offer a reproducible, patient-friendly, and easy guide for preoperative planning in breast reduction surgery. This method may enhance surgical precision and improve aesthetic outcomes.
{"title":"Temporary Tattoo Application Developed Based on 3-dimensional Design in Marking of Breast Reduction/Lift Surgery.","authors":"Mustafa Tezcan","doi":"10.1097/GOX.0000000000007346","DOIUrl":"10.1097/GOX.0000000000007346","url":null,"abstract":"<p><p>Preoperative markings are essential in breast reduction surgery, yet conventional hand-drawn methods may be prone to inaccuracies, particularly in patients with large or ptotic breasts. This study aimed to introduce and evaluate a standardized preoperative drawing method using temporary tattoos based on 3-dimensional (3D) breast modeling. Three-dimensional breast models were created using Blender 3D software, incorporating various base diameters and nipple-areola complex widths. The models were flattened into 2D templates and transferred to skin using temporary tattoos. A 5-step standardized drawing protocol was designed and applied to the simulated model. Ratios between breast base circumference and nipple-areola complex diameter were analyzed to guide excision planning. The 2D templates preserved key proportional relationships derived from 3D analysis. The use of temporary tattoos reduced variability in markings caused by tissue elasticity and human error. Tattoos remained intact for several days, enabling surgeons to perform and verify markings ahead of surgery without disruption to daily activities. Temporary tattoos based on 3D modeling offer a reproducible, patient-friendly, and easy guide for preoperative planning in breast reduction surgery. This method may enhance surgical precision and improve aesthetic outcomes.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 12","pages":"e7346"},"PeriodicalIF":1.8,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12685393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145715376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}