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A Reproducible Method for Donor Site Computed Tomography Measurements in Abdominally Based Autologous Breast Reconstruction. 腹部自体乳房再造术中供体部位计算机断层测量的可重复性方法。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006413
Damini Tandon, Arthur Sletten, Austin Ha, Gary B Skolnick, Paul Commean, Terence Myckatyn

We present an approach for evaluating abdominal computed tomography (CT) scans that generates reproducible measures relevant to donor site morbidity after abdominally based breast reconstruction. Seventeen preoperative CT metrics were measured in 20 patients with software: interanterior superior iliac spine distance; abdominal wall protrusion; interrectus distance; rectus abdominis width, thickness, and width-to-thickness ratio; abdominal wall thickness; subcutaneous fat volume; visceral fat volume; right/left psoas volumes and densities; and right/left rectus abdominis volumes and densities. Two operators performed measures to determine interrater reliability (n = 10). Interclass coefficients (ICCs) were calculated, and Bland-Altman plots were fashioned. Intrarater reliability was excellent (ICC > 0.9, 0.958-1) for 15 measures, and good (0.75 < ICC < 0.9, 0.815-0.853) for 2 measures. Interrater reliability was excellent (ICC > 0.9, 0.912-0.995) for 12 measures and good (0.75 < ICC < 0.9, 0.78-0.896) for 5 measures. Bland-Altman plots confirmed intra/interrater agreement. Our study meets its objective of establishing a protocol for obtaining abdominal CT measurements with high reproducibility and intrarater and interrater reliability. Although this study is not meant to weigh the particular influences of various CT measurements on clinical outcomes, we are now actively studying this with the intention of reporting our findings in the near future. Larger patient cohorts must be leveraged to determine correlations between abdominal CT scan findings and donor site outcomes using machine learning algorithms that generate models for predicting abdominal donor site complications.

我们提出了一种评估腹部计算机断层扫描(CT)的方法,该方法可以产生与腹部乳房重建后供体部位发病率相关的可重复测量。应用软件对20例患者的17项术前CT指标进行测量:髂前上棘间距离;腹壁突出;interrectus距离;腹直肌宽度、厚度及宽厚比;腹壁厚度;皮下脂肪量;内脏脂肪量;右/左腰肌体积和密度;以及左右腹直肌的体积和密度。两名操作员进行了测量,以确定互连器的可靠性(n = 10)。计算类间系数(ICCs),绘制Bland-Altman图。15项测量的内部信度为优秀(ICC > 0.9, 0.958-1), 2项测量的内部信度为良好(0.75 < ICC < 0.9, 0.815-0.853)。测者间信度有12项为优(ICC > 0.9, 0.912-0.995),有5项为良(0.75 < ICC < 0.9, 0.78-0.896)。布兰德-奥特曼阴谋证实了内部/内部协议。本研究的目的是建立一种具有高重复性和内部和内部可靠性的腹部CT测量方案。虽然这项研究并不是为了衡量各种CT测量对临床结果的特定影响,但我们正在积极研究这一问题,并打算在不久的将来报告我们的研究结果。必须利用更大的患者队列来确定腹部CT扫描结果与供体部位结果之间的相关性,使用机器学习算法生成预测腹部供体部位并发症的模型。
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引用次数: 0
Embracing Diversity in Asian Facial Morphologies: Rethinking Terminology in Eyelid Surgery. 拥抱亚洲面部形态的多样性:对眼睑手术术语的重新思考。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006421
Geng-Yi Yong, Alice Siew Ching Goh
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引用次数: 0
An Objective Assessment of Long-term Postoperative Hyperpigmentation in Patients With Apocrine Gland-eliminated Osmidrosis Surgery. 客观评估凋亡性腺鞘膜积液手术患者术后长期色素沉着。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006424
Wen-Tsao Ho

Background: Radical surgery is the best treatment for axillary osmidrosis to eliminate the apocrine glands. However, marked postoperative hyperpigmentation may occur. Clinicians need an objective skin pigmentation examination to identify and treat hyperpigmentation. In this study, we aimed to use the Taylor Hyperpigmentation Scale (an objective visual scale) for evaluating long-term hyperpigmentation after osmidrosis surgery.

Methods: Twenty female patients with Fitzpatrick skin type III-IV who had undergone osmidrosis surgery were included in this study.

Results: The findings demonstrated that although there is an initial variation in the intensity of hyperpigmentation, in the majority of patients, there is a peak in hyperpigmentation between the third and sixth months after surgery. This is then followed by a gradual decline over the ensuing months. Some patients resolve hyperpigmentation completely, suggesting reversibility.

Conclusions: These results can help guide patient expectations and provide suitable postoperative management, thereby improving patient satisfaction and overall quality of life.

背景:根治性手术消除大汗腺是治疗腋臭的最佳方法。然而,术后可能出现明显的色素沉着。临床医生需要客观的皮肤色素沉着检查来识别和治疗色素沉着。在这项研究中,我们的目的是使用泰勒色素沉着量表(一种客观的视觉量表)来评估汗臭手术后的长期色素沉着。方法:选取20例女性Fitzpatrick皮肤III-IV型患者,均行皮肤渗透手术。结果:研究结果表明,虽然色素沉着的强度在最初有变化,但在大多数患者中,色素沉着在手术后的第3至第6个月达到高峰。然后在接下来的几个月里逐渐下降。一些患者完全消除色素沉着,提示可逆性。结论:这些结果有助于指导患者期望,提供合适的术后管理,从而提高患者满意度和整体生活质量。
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引用次数: 0
Innovations in Nipple-areolar Complex Reconstruction: Evaluation of a New Prosthesis. 乳头-乳晕复合重建的创新:一种新型假体的评价。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006410
Michele Riccio, Angelica Aquinati, Mario Fordellone, Nicola Carboni, Andrea Marchesini, Francesco De Francesco

Background: The reconstruction of the nipple-areola complex (NAC) is a crucial step for completing breast restoration with patient satisfaction. Surgical reconstruction or tattooing of the NAC may not be preferable or feasible for some patients. There is no universal method for NAC that is ideal for every patient or clinical situation. Various approaches often do not maintain projection over time. Over time, several techniques have been perfected, including the C-V flap, to improve and support projection for patients with bilateral implant-based reconstructions.

Methods: We used, for the first time, prosthetic devices for NAC reconstruction and examined the safety of these devices associated with ease of implantation and patient satisfaction levels using a survey conducted during a 1-year follow-up. We enrolled 20 individuals who opted for these NAC prostheses following unilateral or bilateral breast reconstruction and following NAC excision.

Results: Ninety percent of the participants expressed satisfaction or high satisfaction with the appearance and balance of the new NAC. The prosthetics enhanced the overall body self-image and self-regard of all the study participants. Except for 4 patients, there were no reports of skin adverse reactions, infections, or erosion.

Conclusions: Encouraged by these auspicious outcomes that indicate a significant rate of safety and satisfaction, we believe that this straightforward, noninvasive, affordable medical device deserves consideration as a reconstructive option for all patients seeking breast reconstruction, promoting full body integrity.

背景:乳头乳晕复合体(NAC)的重建是完成乳房修复和患者满意的关键步骤。手术重建或纹身的NAC可能不可取或可行的一些患者。没有适用于所有患者或临床情况的NAC通用方法。随着时间的推移,各种方法往往不能保持预测。随着时间的推移,包括C-V瓣在内的一些技术已经完善,以改善和支持双侧种植体重建患者的投影。方法:我们首次使用假体装置进行NAC重建,并通过为期1年的随访调查,检查这些装置的安全性与植入的便利性和患者满意度。我们招募了20名在单侧或双侧乳房重建和NAC切除后选择这些NAC假体的患者。结果:90%的参与者对新NAC的外观和平衡表示满意或高度满意。义肢增强了所有研究参与者的整体身体自我形象和自尊。除4例患者外,未见皮肤不良反应、感染或糜烂的报告。结论:这些吉祥的结果表明了显著的安全性和满意度,我们相信这种简单、无创、价格合理的医疗设备值得所有寻求乳房重建的患者考虑作为重建选择,促进全身完整性。
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引用次数: 0
Postoperative Outcomes in Prepectoral Versus Retropectoral Immediate Implant-based Breast Reconstruction Across Body Mass Index Categories. 跨体重指数类别的直肠前与逆行直肠即刻植体乳房重建术的术后结果。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006425
Gauthier Zinner, Jérôme Martineau, Giang Thanh Lam, Daniel Correia, Daniel F Kalbermatten, Carlo M Oranges

Background: Prepectoral (PP) immediate implant-based breast reconstruction (IBBR) is gaining popularity over the retropectoral (RP) breast reconstruction technique. This study aims to compare complication rates across different body mass index (BMI) groups in patients undergoing PP or RP IBBR.

Methods: A monocentric retrospective analysis was conducted on patients who underwent mastectomy and IBBR from January 2018 to December 2023. Preoperative characteristics, BMI, type of mastectomy procedure, PP or RR implant placement, and postoperative outcomes were collected and analyzed.

Results: A total of 217 patients were included, representing 276 IBBRs. The overall complication rate on a per breast basis was 26.4%. The overall complication rate did not differ across BMI groups (P = 0.314) and between PP and RP IBBR (P = 0.8083). In the PP group, anemia rate increased with low BMI (odds ratio [OR] 0.0215, P = 0.033) and skin complications were more frequent with higher BMI (OR 0.0428, P = 0.0389). In the RP group, higher BMI was correlated with a higher seroma rate in the RP IBBR group (OR 1.2045, P = 0.0334) and a longer hospital length of stay (coefficient 0.248, adjusted R² 0.082, SD 0.098, P = 0.014).

Conclusions: PP IBBR was associated with a significantly higher rate of anemia in patients with low BMI, and a significantly higher rate of skin complications in high BMI. RP IBBR was associated with higher seroma rate and longer hospital length of stay in patients with higher BMI.

背景:乳前(PP)即刻植入式乳房重建术(IBBR)正逐渐超越乳后(RP)乳房重建术。本研究旨在比较不同体重指数(BMI)组PP或RP IBBR患者的并发症发生率。方法:对2018年1月至2023年12月接受乳房切除术和IBBR的患者进行单中心回顾性分析。收集并分析术前特征、BMI、乳房切除术类型、PP或RR植入物放置以及术后结果。结果:共纳入217例患者,代表276例ibbr。每个乳房的总并发症发生率为26.4%。总体并发症发生率在BMI组间无差异(P = 0.314), PP组和RP组IBBR组间无差异(P = 0.8083)。在PP组中,BMI越低贫血发生率越高(比值比[OR] 0.0215, P = 0.033), BMI越高皮肤并发症发生率越高(比值比[OR] 0.0428, P = 0.0389)。在RP组中,较高的BMI与RP IBBR组较高的血肿率(OR 1.2045, P = 0.0334)和较长的住院时间相关(系数0.248,调整后R²0.082,SD 0.098, P = 0.014)。结论:PP IBBR与低BMI患者较高的贫血率和高BMI患者较高的皮肤并发症发生率相关。高BMI患者的RP IBBR与较高的血肿率和较长的住院时间相关。
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引用次数: 0
Social Media Growth Blueprint for Plastic Surgeons: Insights and Considerations From Personal Experience. 整形外科医生的社交媒体发展蓝图:个人经验的见解和考虑。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006459
Ahmad Saadya, Tarek El-Tantawy

Background: Social media platforms such as TikTok have recently emerged as influential tools for information dissemination, offering plastic surgeons new opportunities to promote their practices. However, these platforms also present significant challenges regarding online safety, ethical considerations, and the potential spread of misinformation.

Methods: This study analyzes the experience of gaining 100,000 followers on TikTok within 6 months, highlighting the excitement of rapid growth alongside the challenges posed by the potential for misinformation. We propose a strategic approach to leveraging social media effectively and ethically, focusing on storytelling, educational content, and audience engagement; highlighting unique selling propositions; utilizing analytics; and maintaining consistency. Ethical considerations in medical communication are also discussed, emphasizing the need for robust guidelines.

Results: From December 2023 to June 2024, the author posted 56 videos in Arabic, the target market's language. These videos garnered 16,566,900 views and 758,500 likes, with an average video length of 95.36 seconds. This growth led to a 47% increase in nonsurgical aesthetic consultations. Engagement and educational content, such as study tips, received the highest views, totaling 5.6 million, demonstrating the importance of such content in building a follower base for targeted marketing.

Conclusions: Our findings highlight the power and potential risks of social media in healthcare, advocating for a balanced approach that maximizes benefits while mitigating the spread of misinformation.

背景:TikTok等社交媒体平台最近成为有影响力的信息传播工具,为整形外科医生提供了新的推广机会。然而,这些平台也在网络安全、道德考虑和错误信息的潜在传播方面提出了重大挑战。方法:本研究分析了抖音在6个月内获得10万粉丝的经历,突出了快速增长带来的兴奋,以及潜在的错误信息带来的挑战。我们提出了一种有效和道德地利用社交媒体的战略方法,重点是讲故事、教育内容和受众参与;突出独特的销售主张;利用分析;保持一致性。还讨论了医学传播中的伦理考虑,强调需要制定强有力的指导方针。结果:从2023年12月到2024年6月,作者用目标市场的语言阿拉伯语发布了56个视频。这些视频获得了1656.69万次观看和758500个赞,平均视频长度为95.36秒。这一增长导致非手术美容咨询增加了47%。参与和教育内容,如学习技巧,获得了最高的浏览量,总计560万,证明了这些内容在建立目标营销的追随者基础方面的重要性。结论:我们的研究结果强调了社交媒体在医疗保健中的力量和潜在风险,倡导一种平衡的方法,在减少错误信息传播的同时最大化利益。
{"title":"Social Media Growth Blueprint for Plastic Surgeons: Insights and Considerations From Personal Experience.","authors":"Ahmad Saadya, Tarek El-Tantawy","doi":"10.1097/GOX.0000000000006459","DOIUrl":"10.1097/GOX.0000000000006459","url":null,"abstract":"<p><strong>Background: </strong>Social media platforms such as TikTok have recently emerged as influential tools for information dissemination, offering plastic surgeons new opportunities to promote their practices. However, these platforms also present significant challenges regarding online safety, ethical considerations, and the potential spread of misinformation.</p><p><strong>Methods: </strong>This study analyzes the experience of gaining 100,000 followers on TikTok within 6 months, highlighting the excitement of rapid growth alongside the challenges posed by the potential for misinformation. We propose a strategic approach to leveraging social media effectively and ethically, focusing on storytelling, educational content, and audience engagement; highlighting unique selling propositions; utilizing analytics; and maintaining consistency. Ethical considerations in medical communication are also discussed, emphasizing the need for robust guidelines.</p><p><strong>Results: </strong>From December 2023 to June 2024, the author posted 56 videos in Arabic, the target market's language. These videos garnered 16,566,900 views and 758,500 likes, with an average video length of 95.36 seconds. This growth led to a 47% increase in nonsurgical aesthetic consultations. Engagement and educational content, such as study tips, received the highest views, totaling 5.6 million, demonstrating the importance of such content in building a follower base for targeted marketing.</p><p><strong>Conclusions: </strong>Our findings highlight the power and potential risks of social media in healthcare, advocating for a balanced approach that maximizes benefits while mitigating the spread of misinformation.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 1","pages":"e6459"},"PeriodicalIF":1.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The "Arrow Factor" in Gluteoplasty and Brazilian Butt Lift. 臀部整形术和巴西臀部提拉术中的 "箭头因素"。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-10 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006468
Edoardo Raposio, Alice Morello, Giorgio Raposio

The gluteal region has become a rising area of interest in plastic surgery in recent years, as reflected in body contouring surgery trends. In this study, the authors explain what the arrow effect consists of and how to highlight it during a Brazilian butt lift or a gluteal liposculpture: liposuction of the sacral triangle, fat grafting of the upper gluteal quadrants, liposuction of the dimples of Venus and of the midline superficially to the spinal column, and fat grafting of the erector spinae muscles.

近年来,臀部区域已成为整形手术的一个新兴领域,这反映在身体轮廓手术的趋势中。在这项研究中,作者解释了箭头效应的组成,以及如何在巴西臀举或臀脂塑形术中突出它:骶骨三角吸脂,臀上象限脂肪移植,维纳斯酒窝和脊柱中线浅表脂肪移植,以及竖脊肌脂肪移植。
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引用次数: 0
Brunelli (Dorsoulnar) Flap for the Reconstruction of Defect of the Thumb Nail Unit After Oncological Resections With Mohs Micrographic Surgery. 莫氏显微摄影法重建肿瘤切除拇指甲缺损的Brunelli (Dorsoulnar)皮瓣。
IF 1.5 Q3 SURGERY Pub Date : 2024-12-26 eCollection Date: 2024-12-01 DOI: 10.1097/GOX.0000000000006401
Felipe Mesa, Oscar Leal, María Elena Ramos

Background: The Brunelli flap is an option in the reconstruction of the thumb after trauma or oncological resections. The arc of movement of the flap makes it possible to resolve defects in the proximal, palmar, dorsal, and lateral regions.

Methods: We present a case series of 11 patients in whom a Brunelli flap was performed for postoncological reconstruction, melanoma in situ, and invasive squamous cell carcinoma of the thumb nail unit associated with Mohs micrographic surgery. This combination has not been described before.

Results: The reconstruction was carried out using a Brunelli flap, incorporating certain variations to the original technique. Clinical follow-up was performed during a 1-year period. All flaps showed good viability. In 3 flaps, there was mild distal suffering that resolved with local healing. Three patients presented hypersensitivity in the distal part, which was managed with physical therapy. The functionality of the thumb was not altered in any case, and there were no complications in the donor site. No tumor recurrence was documented in any patient.

Conclusions: The use of the Brunelli flap to reconstruct the nail unit after an oncological resection with Mohs surgery is a good alternative. The advantages include a dorsal artery as a constant vessel and a homodigital flap that does not cause morbidity in the donor area, and with Mohs surgery, amputation is avoided. Disadvantages include lack of sensation of the flap. Some limitations of our study are the sample size and lack of long-term follow-up.

背景:布鲁内利皮瓣是拇指创伤或肿瘤切除后重建的一种选择。皮瓣的弧形运动使得解决近端、掌端、背侧和外侧区域的缺损成为可能。方法:我们报告了11例患者的病例系列,其中Brunelli皮瓣用于肿瘤后重建,原位黑色素瘤和与Mohs显微摄影手术相关的拇指甲单元浸润性鳞状细胞癌。这种组合以前没有被描述过。结果:采用布鲁内利皮瓣进行重建,并在原有技术的基础上进行了一定的改进。临床随访1年。所有皮瓣均显示良好的生存能力。在3个皮瓣中,有轻微的远端疼痛,局部愈合。3例患者出现远端过敏,采用物理治疗。在任何情况下,拇指的功能都没有改变,供体部位也没有并发症。所有患者均无肿瘤复发记录。结论:应用Brunelli皮瓣重建肿瘤切除Mohs手术后甲单元是一种较好的选择。其优点包括背动脉作为一个恒定的血管和同指瓣,不会引起供体区域的发病率,并且使用Mohs手术,可以避免截肢。缺点包括缺乏皮瓣的感觉。本研究的局限性在于样本量和缺乏长期随访。
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引用次数: 0
Pilot Study: Human Adipose Tissue Allograft for Fat Pad Defects in Patients With Preulcerative Lesions. 初步研究:人脂肪组织异体移植治疗溃疡前病变患者脂肪垫缺损。
IF 1.5 Q3 SURGERY Pub Date : 2024-12-26 eCollection Date: 2024-12-01 DOI: 10.1097/GOX.0000000000006404
Matthew J Regulski, Molly C Saunders, Sharron E McCulloch, Alla Danilkovitch

Background: Loss or displacement of a fat pad on the foot increases plantar pressure, leading to pain and plantar ulcers. These ulcers, especially in patients with diabetic neuropathy, have high recurrence rates, often resulting in amputations. Standard of care focuses on reducing plantar pressure with shoe padding or orthotic devices, leaving the restoration of the fat pad as an unmet medical need. To address this, a human cryopreserved adipose tissue (hCAT) allograft has been developed to repair adipose tissue defects.

Methods: Scientific characterization of hCAT included assessments of its structural properties, immunogenicity, persistence, and remodeling in both in vitro and in vivo models. The incidence of adverse events and ulcer recurrence was analyzed retrospectively in 12 patients with diabetic neuropathy with preulcerative lesions who received 1.5-3.0 mL subcutaneous hCAT implants in areas with fat pad defects.

Results: When implanted in patients, hCAT remained palpable at the implantation sites, and no ulcerations occurred for an average of 6.4 months (range, 2-10 months). No product-related adverse events have been recorded to date. Long-term follow-up for implanted patients is ongoing.

Conclusions: Use of hCAT seems to be safe and potentially beneficial for managing patients at risk for plantar ulcerations. Further studies are warranted to evaluate hCAT's potential to manage patients at high risk for plantar ulcer formation.

背景:足部脂肪垫的丢失或移位会增加足底压力,导致疼痛和足底溃疡。这些溃疡,特别是糖尿病神经病变患者,复发率高,常常导致截肢。标准护理侧重于用鞋垫或矫形装置减少足底压力,而将脂肪垫的修复作为未满足的医疗需求。为了解决这个问题,人类冷冻保存脂肪组织(hCAT)异体移植物已被开发用于修复脂肪组织缺陷。方法:hCAT的科学表征包括在体外和体内模型中评估其结构特性、免疫原性、持久性和重塑。回顾性分析12例伴有溃疡前病变的糖尿病神经病变患者在脂肪垫缺损区皮下植入1.5 ~ 3.0 mL hCAT的不良事件和溃疡复发的发生率。结果:患者植入后,hCAT在植入部位仍可触及,平均6.4个月(范围2-10个月)未发生溃疡。到目前为止,没有记录到与产品相关的不良事件。植入患者的长期随访正在进行中。结论:使用hCAT似乎是安全的,对管理有足底溃疡风险的患者可能有益。需要进一步的研究来评估hCAT治疗足底溃疡形成高风险患者的潜力。
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引用次数: 0
A Systematic Review and Meta-analysis of Single-group Studies Assessing the Role of Calcium Hydroxylapatite in Aesthetic Enhancements and Satisfaction. 评估羟基磷灰石钙在美学增强和满意度中的作用的单组研究的系统回顾和荟萃分析。
IF 1.5 Q3 SURGERY Pub Date : 2024-12-26 eCollection Date: 2024-12-01 DOI: 10.1097/GOX.0000000000006400
Mojgan Amiri, Renald Meçani, Christa D Niehot, Terri L Phillips, Katherine Goldie, Janina Kolb, Taulant Muka, Hua Daughtry

Background: Many studies assess aesthetic effectiveness of calcium hydroxylapatite (CaHA), with single-group designs as the most frequently applied designs in practice. This study systematically reviewed CaHA's effectiveness for aesthetic purposes among these studies.

Methods: A comprehensive search was conducted across 5 bibliographic databases. Single-group studies with at least 10 human adults were included. Summary measures of patients satisfaction and global aesthetic improvement scores were combined using the generalized linear mixed model. This systematic review adhered to the PRISMA reporting standards.

Results: Of 3131 records, 46 single-group studies, majority focused on facial areas (n = 32), were included for final qualitative analysis. A total number of 27 studies were included in the meta-analysis. Findings of the meta-analysis showed that 98% (95% confidence interval [CI], 91%-99%; I 2, 0.0%) of patients were satisfied with the injection results in the facial area and 90% (95% CI, 67%-97%, I 2, 35%) in other treated body areas. Also, patients reported 89% (95% CI, 76%-96%; I 2, 65%) improvement on the global aesthetic improvement scale in facial areas and 94% (95% CI, 75%-99%; I 2, 0.0%) in other treated regions. Similarly, investigators reported global aesthetic improvement in 92% of patients (95% CI, 33%-100%; I 2, 92%) in facial areas and 95% (95% CI, 1%-100%; I 2, 89%) in other treated areas.

Conclusions: Our findings showed aesthetic improvements and satisfaction following CaHA injections in both facial and nonfacial areas. However, studies focusing on nonfacial regions are limited. We recommend more rigorously designed trials to better understand CaHA's clinical effects.

背景:许多研究评估了羟基磷灰石钙(CaHA)的美学效果,其中单组设计是实践中最常用的设计。本研究系统地回顾了这些研究中CaHA在美学目的方面的有效性。方法:对5个文献数据库进行综合检索。纳入了至少10名成人的单组研究。采用广义线性混合模型将患者满意度和整体审美改善评分综合起来。该系统审查遵循PRISMA报告标准。结果:在3131份记录中,46项单组研究(n = 32)被纳入最终的定性分析,其中大多数集中在面部区域。meta分析共纳入了27项研究。meta分析结果显示98%(95%置信区间[CI], 91%-99%;2, 0.0%)的患者对面部注射效果满意,90% (95% CI, 67%-97%, 2, 35%)的患者对其他治疗部位的注射效果满意。此外,患者报告89% (95% CI, 76%-96%;在面部区域的整体美学改善量表上有65%的改善,94% (95% CI, 75%-99%;在其他治疗区域(2.0.0%)。同样,研究人员报告92%的患者整体美观改善(95% CI, 33%-100%;I 2, 92%), 95% (95% CI, 1%-100%;(2.89%)在其他治疗区域。结论:我们的研究结果显示,在面部和非面部区域注射CaHA后,美学改善和满意度。然而,针对非面部区域的研究是有限的。我们建议更严格地设计试验,以更好地了解CaHA的临床效果。
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引用次数: 0
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