Pub Date : 2024-11-07eCollection Date: 2024-11-01DOI: 10.1097/GOX.0000000000006329
Keenan S Fine, Pradeep Attaluri, Peter J Wirth, Ellen C Shaffrey, Venkat K Rao
{"title":"Recent Increases in Violence Against Physicians and Plastic Surgeons.","authors":"Keenan S Fine, Pradeep Attaluri, Peter J Wirth, Ellen C Shaffrey, Venkat K Rao","doi":"10.1097/GOX.0000000000006329","DOIUrl":"https://doi.org/10.1097/GOX.0000000000006329","url":null,"abstract":"","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 11","pages":"e6329"},"PeriodicalIF":1.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-07eCollection Date: 2024-11-01DOI: 10.1097/GOX.0000000000006310
Mollie B Smith, Ernest S Chiu, Laura L Kimberly
{"title":"Treating Xylazine-associated Wounds: Considering a Role for Plastic Surgeons.","authors":"Mollie B Smith, Ernest S Chiu, Laura L Kimberly","doi":"10.1097/GOX.0000000000006310","DOIUrl":"https://doi.org/10.1097/GOX.0000000000006310","url":null,"abstract":"","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 11","pages":"e6310"},"PeriodicalIF":1.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-05eCollection Date: 2024-11-01DOI: 10.1097/GOX.0000000000006276
Rafael Reynoso, Alfonso Echeverría, Samaria Estefania Mejia Rivera, Jazmín Villasana Sánchez
Total avulsion of the scalp represents a therapeutic challenge with no consensus nowadays. Currently, microsurgical reimplantation is the reconstructive procedure of choice, but in case it is not feasible, the literature does not define an ideal treatment for an immediate reconstruction. We present the case of an 18-year-old woman with total avulsion of the scalp and forehead skin without possibility of reimplantation. We performed the surgical reconstruction with a latissimus dorsi free flap, and to achieve greater malleability, the flap was harvested without fascia. A large coverage was immediately achieved, and 1 year after the procedure, the patient showed excellent cranial symmetry and a high level of satisfaction. The optimal treatment of total avulsion of the scalp with no option of reimplantation remains a challenge. In our case, the subfascial dissection increased the flap area to cover the defect. Our procedure could be considered as an alternative surgical strategy in flap harvest, but more cases are needed.
{"title":"Latissimus Dorsi Free Flap: Subfascial Flap Dissection in a Case of Scalp and Forehead Reconstruction.","authors":"Rafael Reynoso, Alfonso Echeverría, Samaria Estefania Mejia Rivera, Jazmín Villasana Sánchez","doi":"10.1097/GOX.0000000000006276","DOIUrl":"10.1097/GOX.0000000000006276","url":null,"abstract":"<p><p>Total avulsion of the scalp represents a therapeutic challenge with no consensus nowadays. Currently, microsurgical reimplantation is the reconstructive procedure of choice, but in case it is not feasible, the literature does not define an ideal treatment for an immediate reconstruction. We present the case of an 18-year-old woman with total avulsion of the scalp and forehead skin without possibility of reimplantation. We performed the surgical reconstruction with a latissimus dorsi free flap, and to achieve greater malleability, the flap was harvested without fascia. A large coverage was immediately achieved, and 1 year after the procedure, the patient showed excellent cranial symmetry and a high level of satisfaction. The optimal treatment of total avulsion of the scalp with no option of reimplantation remains a challenge. In our case, the subfascial dissection increased the flap area to cover the defect. Our procedure could be considered as an alternative surgical strategy in flap harvest, but more cases are needed.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 11","pages":"e6276"},"PeriodicalIF":1.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-05eCollection Date: 2024-11-01DOI: 10.1097/GOX.0000000000006273
Jane N Ewing, Chris Amro, Ashley Chang, Zachary Gala, Mehdi S Lemdani, Robyn B Broach, John P Fischer, Joseph M Serletti, Saïd C Azoury
Background: With marijuana use on the rise, its influence on surgical outcomes, particularly for breast reduction, warrants investigation. This study aims to clarify marijuana's effects on breast reduction surgery outcomes, given its limited research focus despite potential perioperative implications.
Methods: A retrospective review was conducted from 2016 to 2022 of patients with/without marijuana use undergoing breast reduction. Propensity score-matching considered age, body mass index, ptosis, and breast tissue mass. Patient demographics, clinical attributes, and postoperative details were analyzed. Quality-of-life (QoL) changes were gauged using pre- and postoperative BREAST-Q.
Results: Of 415 patients who underwent breast reduction, 140 patients documented marijuana use. After propensity matching, a total of 108 patients (54 marijuana users versus 54 nonusers) were analyzed. The average age was 39 years ± 12 and body mass index 30.1 kg/m2 ± 5.3. There were no differences between the 2 groups in comorbidities, breast symmetry, excision patterns, pedicle use, or drain count (P > 0.05). Furthermore, surgical outcomes including surgical site occurrences, scarring, pain levels, hypersensitivity, or sensation loss were comparable between the groups (P > 0.05). There were also no differences in number of readmissions, reoperations, or emergency department visits (P > 0.05). Both groups showed enhanced postoperative QoL, regardless of marijuana usage.
Conclusions: This study indicates that marijuana use does not significantly impact breast reduction surgery outcomes. Comparable surgical results and postoperative QoL improvements were observed in both marijuana users and nonusers. This study provides surgeons with the knowledge to offer more informed patient counseling regarding the implications of marijuana use in relation to breast reduction procedures.
{"title":"Marijuana and Its Implications in Breast Reduction Surgery Outcomes and Quality of Life: A Matched Analysis.","authors":"Jane N Ewing, Chris Amro, Ashley Chang, Zachary Gala, Mehdi S Lemdani, Robyn B Broach, John P Fischer, Joseph M Serletti, Saïd C Azoury","doi":"10.1097/GOX.0000000000006273","DOIUrl":"10.1097/GOX.0000000000006273","url":null,"abstract":"<p><strong>Background: </strong>With marijuana use on the rise, its influence on surgical outcomes, particularly for breast reduction, warrants investigation. This study aims to clarify marijuana's effects on breast reduction surgery outcomes, given its limited research focus despite potential perioperative implications.</p><p><strong>Methods: </strong>A retrospective review was conducted from 2016 to 2022 of patients with/without marijuana use undergoing breast reduction. Propensity score-matching considered age, body mass index, ptosis, and breast tissue mass. Patient demographics, clinical attributes, and postoperative details were analyzed. Quality-of-life (QoL) changes were gauged using pre- and postoperative BREAST-Q.</p><p><strong>Results: </strong>Of 415 patients who underwent breast reduction, 140 patients documented marijuana use. After propensity matching, a total of 108 patients (54 marijuana users versus 54 nonusers) were analyzed. The average age was 39 years ± 12 and body mass index 30.1 kg/m<sup>2</sup> ± 5.3. There were no differences between the 2 groups in comorbidities, breast symmetry, excision patterns, pedicle use, or drain count (<i>P</i> > 0.05). Furthermore, surgical outcomes including surgical site occurrences, scarring, pain levels, hypersensitivity, or sensation loss were comparable between the groups (<i>P</i> > 0.05). There were also no differences in number of readmissions, reoperations, or emergency department visits (<i>P</i> > 0.05). Both groups showed enhanced postoperative QoL, regardless of marijuana usage.</p><p><strong>Conclusions: </strong>This study indicates that marijuana use does not significantly impact breast reduction surgery outcomes. Comparable surgical results and postoperative QoL improvements were observed in both marijuana users and nonusers. This study provides surgeons with the knowledge to offer more informed patient counseling regarding the implications of marijuana use in relation to breast reduction procedures.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 11","pages":"e6273"},"PeriodicalIF":1.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-05eCollection Date: 2024-11-01DOI: 10.1097/GOX.0000000000006281
Benedikt Schäfer, Gerrit Freund, Jonah Orr, Kay Nolte, Joachim Weis, Jörg Bahm, Justus P Beier
Peripheral nerve surgery, particularly in cases of nerve compression syndrome (NCS), necessitates a comprehensive evaluation of intraneural blood flow, as localized reductions in nerve perfusion are integral to the etiopathogenesis of such conditions. Although nerve perfusion is currently guided by morphologic characteristics, this assessment is subjective and prone to bias. Intraoperative fluorescence-assisted perfusion imaging with indocyanine green (ICG) is an established tool in flap and lymphatic surgery to objectively assess perfusion intraoperatively. However, only a few unspecific applications of ICG in peripheral nerve surgery have been published so far. In this study, we performed intraoperative perfusion imaging using ICG in 16 consecutive operations within the peripheral nervous system, including microsurgical reconstructions after obstetric brachial plexus injury, decompression for NCS, and vascularized ulnar nerve interposition transfers. Our findings show the utility of ICG in delineating healthy perfusion borders at proximal and distal stump levels after neuroma resection, and we demonstrate a correlation between histological findings and these clinically observed perfusion patterns. In NCS cases, we demonstrate that ICG imaging is effective in highlighting reduced perfusion predecompression and improved perfusion postdecompression. Additionally, ICG proved valuable for assessing perfusion of free vascularized nerve grafts. Intraoperative ICG perfusion imaging is a valuable tool during surgery of the peripheral nervous system, providing insights into the etiopathogenesis of NCS and aiding in the visualization of perfusion. This study underscores the potential of ICG in nerve surgery and its applicability for improving surgical outcomes and advancing our understanding of peripheral nerve pathologies.
{"title":"Technique and Expected Benefit of Intraoperative Perfusion Imaging of Peripheral Nerves.","authors":"Benedikt Schäfer, Gerrit Freund, Jonah Orr, Kay Nolte, Joachim Weis, Jörg Bahm, Justus P Beier","doi":"10.1097/GOX.0000000000006281","DOIUrl":"10.1097/GOX.0000000000006281","url":null,"abstract":"<p><p>Peripheral nerve surgery, particularly in cases of nerve compression syndrome (NCS), necessitates a comprehensive evaluation of intraneural blood flow, as localized reductions in nerve perfusion are integral to the etiopathogenesis of such conditions. Although nerve perfusion is currently guided by morphologic characteristics, this assessment is subjective and prone to bias. Intraoperative fluorescence-assisted perfusion imaging with indocyanine green (ICG) is an established tool in flap and lymphatic surgery to objectively assess perfusion intraoperatively. However, only a few unspecific applications of ICG in peripheral nerve surgery have been published so far. In this study, we performed intraoperative perfusion imaging using ICG in 16 consecutive operations within the peripheral nervous system, including microsurgical reconstructions after obstetric brachial plexus injury, decompression for NCS, and vascularized ulnar nerve interposition transfers. Our findings show the utility of ICG in delineating healthy perfusion borders at proximal and distal stump levels after neuroma resection, and we demonstrate a correlation between histological findings and these clinically observed perfusion patterns. In NCS cases, we demonstrate that ICG imaging is effective in highlighting reduced perfusion predecompression and improved perfusion postdecompression. Additionally, ICG proved valuable for assessing perfusion of free vascularized nerve grafts. Intraoperative ICG perfusion imaging is a valuable tool during surgery of the peripheral nervous system, providing insights into the etiopathogenesis of NCS and aiding in the visualization of perfusion. This study underscores the potential of ICG in nerve surgery and its applicability for improving surgical outcomes and advancing our understanding of peripheral nerve pathologies.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 11","pages":"e6281"},"PeriodicalIF":1.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-05eCollection Date: 2024-11-01DOI: 10.1097/GOX.0000000000006280
Parintosa Atmodiwirjo, Mohamad Rachadian Ramadan, Aditya Wicaksana, Michael Djohan, Nadira Fildza Amanda, Nadhira Anindita Ralena, Ismail Hadisoebroto Dilogo, Purnomo Sidi Priambodo, Retno Asti Werdhani, Em Yunir, Lisnawati Rachmadi, Alida Roswita Harahap, Prasandhya Astagiri Yusuf, Lisa Hasibuan, Daisuke Mito
Background: Assessing perfusion in free flaps is crucial in clinical practice. Indocyanine green (ICG) angiography offers a more objective and reproducible method, utilizing near-infrared imaging to monitor flap vascularization. This study aims to evaluate the efficacy of diluted ICG as a tool for assessing free flap perfusion.
Methods: This pilot randomized clinical trial compares the fluorescence concentrations of ICG at 3 different dilutions: 5 mg/mL (standard concentration), 2.5 mg/mL (half the standard concentration), and 0.5 mg/mL (one-tenth of the standard concentration). Inclusion criteria required participants to have serum albumin levels above 3 g/dL, hemoglobin levels over 10 g/dL, and no comorbidities. Participants were randomized into 3 groups based on ICG concentration. Fluorescence analysis was performed using ImageJ software to determine mean gray values. Both surgeons and data analysts were blinded to the ICG concentrations administered, ensuring unbiased evaluation.
Results: Forty-five patients undergoing free flap surgery, predominantly male (60%) with a mean age of 37.76 ± 19.79 years and a mean body mass index of 21.23 ± 4.49 kg/m², primarily received osteoseptocutaneous fibular free flaps (46.67%), with an average skin flap area of 66.07 ± 46.94 cm². The primary etiology was underlying tumors (84.4%), with the head and neck as the most common reconstruction site (82.2%). The superior thyroid artery was the most frequently used recipient vessel (37.78%). Analysis revealed mean gray values of 64.10 ± 8.27 (5 mg/mL), 79.03 ± 2.7 (2.5 mg/mL), and 33.56 ± 3.47 (0.5 mg/mL), with 2.5 mg/mL yielding the highest value (P < 0.001).
Conclusions: Findings suggest using 2.5 mg/mL concentration enhances fluorescence emission, offering a dosage alternative in clinical practice.
{"title":"Diluted Indocyanine Green Angiography: A Novel Approach to Free Flap Perfusion Evaluation in Reconstructive Microsurgery.","authors":"Parintosa Atmodiwirjo, Mohamad Rachadian Ramadan, Aditya Wicaksana, Michael Djohan, Nadira Fildza Amanda, Nadhira Anindita Ralena, Ismail Hadisoebroto Dilogo, Purnomo Sidi Priambodo, Retno Asti Werdhani, Em Yunir, Lisnawati Rachmadi, Alida Roswita Harahap, Prasandhya Astagiri Yusuf, Lisa Hasibuan, Daisuke Mito","doi":"10.1097/GOX.0000000000006280","DOIUrl":"10.1097/GOX.0000000000006280","url":null,"abstract":"<p><strong>Background: </strong>Assessing perfusion in free flaps is crucial in clinical practice. Indocyanine green (ICG) angiography offers a more objective and reproducible method, utilizing near-infrared imaging to monitor flap vascularization. This study aims to evaluate the efficacy of diluted ICG as a tool for assessing free flap perfusion.</p><p><strong>Methods: </strong>This pilot randomized clinical trial compares the fluorescence concentrations of ICG at 3 different dilutions: 5 mg/mL (standard concentration), 2.5 mg/mL (half the standard concentration), and 0.5 mg/mL (one-tenth of the standard concentration). Inclusion criteria required participants to have serum albumin levels above 3 g/dL, hemoglobin levels over 10 g/dL, and no comorbidities. Participants were randomized into 3 groups based on ICG concentration. Fluorescence analysis was performed using ImageJ software to determine mean gray values. Both surgeons and data analysts were blinded to the ICG concentrations administered, ensuring unbiased evaluation.</p><p><strong>Results: </strong>Forty-five patients undergoing free flap surgery, predominantly male (60%) with a mean age of 37.76 ± 19.79 years and a mean body mass index of 21.23 ± 4.49 kg/m², primarily received osteoseptocutaneous fibular free flaps (46.67%), with an average skin flap area of 66.07 ± 46.94 cm². The primary etiology was underlying tumors (84.4%), with the head and neck as the most common reconstruction site (82.2%). The superior thyroid artery was the most frequently used recipient vessel (37.78%). Analysis revealed mean gray values of 64.10 ± 8.27 (5 mg/mL), 79.03 ± 2.7 (2.5 mg/mL), and 33.56 ± 3.47 (0.5 mg/mL), with 2.5 mg/mL yielding the highest value (<i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>Findings suggest using 2.5 mg/mL concentration enhances fluorescence emission, offering a dosage alternative in clinical practice.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 11","pages":"e6280"},"PeriodicalIF":1.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-05eCollection Date: 2024-11-01DOI: 10.1097/GOX.0000000000006278
Emily S Chwa, Breanna Baltrusch, Erin Claussen, Sophia Allison, Nikhil D Shah, Akira Yamada
Modern approaches to autogenous auricular reconstruction involve a multistage approach where ear elevation is an independent procedure. The goal is to project the reconstructed ear at an anatomically accurate and symmetric auriculocephalic angle, but postoperative scar contraction may adversely affect the long-term outcomes. An ear elevation splint was developed to provide rigid support for the auricle during the acute healing period to promote lasting elevation. The splint is low cost, made from commonly used orthotic materials, and can be conveniently customized for each patient in less than 15 minutes.
{"title":"Novel, Low-cost Ear Elevation Splint for Auricular Construction.","authors":"Emily S Chwa, Breanna Baltrusch, Erin Claussen, Sophia Allison, Nikhil D Shah, Akira Yamada","doi":"10.1097/GOX.0000000000006278","DOIUrl":"10.1097/GOX.0000000000006278","url":null,"abstract":"<p><p>Modern approaches to autogenous auricular reconstruction involve a multistage approach where ear elevation is an independent procedure. The goal is to project the reconstructed ear at an anatomically accurate and symmetric auriculocephalic angle, but postoperative scar contraction may adversely affect the long-term outcomes. An ear elevation splint was developed to provide rigid support for the auricle during the acute healing period to promote lasting elevation. The splint is low cost, made from commonly used orthotic materials, and can be conveniently customized for each patient in less than 15 minutes.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 11","pages":"e6278"},"PeriodicalIF":1.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-05eCollection Date: 2024-11-01DOI: 10.1097/GOX.0000000000006275
Ankur Khajuria, Hamid Reza Khademi Mansour, Ibrahim Muhammad, Akua Asare, Iin Tammasse, Jonathan Suresh, Christopher Leiberman, Niels Pacheco-Barrios, Stav Brown, Teoman Dogan, Rod Rohrich
Background: Perioperative bleeding is a challenge in rhinoplasty and septoplasty. Tranexamic acid (TXA) may help reduce this, but its effectiveness is unclear. This systematic review and meta-analysis aimed to evaluate TXA's impact on bleeding in these procedures.
Methods: The protocol was registered a priori to PROSPERO (CRD42023393458). PubMed, Embase, Google Scholar, and Web of Science were searched from inception to October 2023. Eligible studies were randomized controlled trials of adult patients undergoing rhinoplasty or septoplasty. Primary outcomes were intraoperative blood loss, surgery duration, and surgeon satisfaction. A random-effects model was used. Methodological quality was assessed using GRADE. The risk of bias was assessed using Cochrane's RoB 2 tool for randomized studies.
Results: The search yielded 154 results; 11 randomized controlled trials, with 968 patients, were included. The meta-analysis showed a significant reduction in intraoperative blood loss with TXA (MD -39.67; 95% CI: -15.10 to -64.24; P = 0.002) and superior surgeon satisfaction in favor of TXA use (SMD -2.73; 95% CI: -5.33 to -0.12; P = 0.04). Subgroup analyses for intraoperative blood loss, according to administration routes, were also in favor of intravenous TXA (MD -13.02; 95% CI: -1.65 to -24.38; P = 0.02) and oral TXA (MD -44.98; 95% CI: -83.66 to -6.31; P = 0.02); no statistical difference was noted in surgery duration (MD -0.99; 95% CI: 0.63 to -2.81; P = 0.23). All studies were found to be of high quality, with low bias.
Conclusions: The findings support TXA's efficacy in reducing blood loss during rhinoplasty and septoplasty, with high surgeon satisfaction.
{"title":"Tranexamic Acid in Rhinoplasty and Septoplasty: A Systematic Review and Meta-analysis of Randomized Controlled Trials.","authors":"Ankur Khajuria, Hamid Reza Khademi Mansour, Ibrahim Muhammad, Akua Asare, Iin Tammasse, Jonathan Suresh, Christopher Leiberman, Niels Pacheco-Barrios, Stav Brown, Teoman Dogan, Rod Rohrich","doi":"10.1097/GOX.0000000000006275","DOIUrl":"10.1097/GOX.0000000000006275","url":null,"abstract":"<p><strong>Background: </strong>Perioperative bleeding is a challenge in rhinoplasty and septoplasty. Tranexamic acid (TXA) may help reduce this, but its effectiveness is unclear. This systematic review and meta-analysis aimed to evaluate TXA's impact on bleeding in these procedures.</p><p><strong>Methods: </strong>The protocol was registered a priori to PROSPERO (CRD42023393458). PubMed, Embase, Google Scholar, and Web of Science were searched from inception to October 2023. Eligible studies were randomized controlled trials of adult patients undergoing rhinoplasty or septoplasty. Primary outcomes were intraoperative blood loss, surgery duration, and surgeon satisfaction. A random-effects model was used. Methodological quality was assessed using GRADE. The risk of bias was assessed using Cochrane's RoB 2 tool for randomized studies.</p><p><strong>Results: </strong>The search yielded 154 results; 11 randomized controlled trials, with 968 patients, were included. The meta-analysis showed a significant reduction in intraoperative blood loss with TXA (MD -39.67; 95% CI: -15.10 to -64.24; <i>P</i> = 0.002) and superior surgeon satisfaction in favor of TXA use (SMD -2.73; 95% CI: -5.33 to -0.12; <i>P</i> = 0.04). Subgroup analyses for intraoperative blood loss, according to administration routes, were also in favor of intravenous TXA (MD -13.02; 95% CI: -1.65 to -24.38; <i>P</i> = 0.02) and oral TXA (MD -44.98; 95% CI: -83.66 to -6.31; <i>P</i> = 0.02); no statistical difference was noted in surgery duration (MD -0.99; 95% CI: 0.63 to -2.81; <i>P</i> = 0.23). All studies were found to be of high quality, with low bias.</p><p><strong>Conclusions: </strong>The findings support TXA's efficacy in reducing blood loss during rhinoplasty and septoplasty, with high surgeon satisfaction.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 11","pages":"e6275"},"PeriodicalIF":1.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-05eCollection Date: 2024-11-01DOI: 10.1097/GOX.0000000000006267
Madeline J O'Connor, Kristin N Huffman, Kelly Ho, Sammer Marzouk, Rolando J Casas Fuentes, Kenneth L Zhang, Bradley A Melnick, Payton J Sparks, Raiven Harris, Angelica V Bartler, Ashley Collinsworth, Leah Griffin, Robert D Galiano
Background: Periprosthetic infection after breast reconstruction is not uncommon and can result in loss of the implant pocket and negative patient outcomes. Management of these infections typically involves removal of the prosthesis, treatment with antibiotics, and delayed reconstruction upon infection resolution. The impact of adjunctive use of negative pressure wound therapy with instillation and dwell (NPWTi-d) on breast pocket salvage rates, time to implant reinsertion, and related outcomes was examined.
Methods: A systematic literature search using PubMed, Cochrane, OVID, Scopus, and Embase was conducted to identify peer-reviewed articles written in English and published between January 2004 and April 2023 that examined NPWTi-d use in the breast pocket with a history of periprosthetic infection after breast reconstruction.
Results: Of the 1703 publications, 6 studies met inclusion criteria, representing 115 patients and 122 breasts. The overall breast pocket salvage rate with NPWTi-d across studies was approximately 92%. In the 6 studies that included prosthesis type and radiation history, overall salvage rates were 97.8% (45 of 46) for pockets containing implants and 93.8% (15 of 16) for pockets containing tissue expanders. Salvage rates were 85.7% (12 of 14) and 91.7% (53 of 58) for irradiated and nonirradiated breasts, respectively. Mean time to implant reinsertion ranged from 2.3 to 10.3 days.
Conclusions: In this review, antibiotic therapy along with adjunctive use of NPWTi-d for periprosthetic infections after breast reconstructions was associated with high rates of breast pocket salvage and reduced time to implant reinsertion. Larger prospective and randomized trials are needed to better understand and optimize the effectiveness of NPWTi-d in this population.
{"title":"Negative Pressure Wound Therapy with Instillation for Periprosthetic Infection after Breast Reconstruction: A Systematic Review.","authors":"Madeline J O'Connor, Kristin N Huffman, Kelly Ho, Sammer Marzouk, Rolando J Casas Fuentes, Kenneth L Zhang, Bradley A Melnick, Payton J Sparks, Raiven Harris, Angelica V Bartler, Ashley Collinsworth, Leah Griffin, Robert D Galiano","doi":"10.1097/GOX.0000000000006267","DOIUrl":"10.1097/GOX.0000000000006267","url":null,"abstract":"<p><strong>Background: </strong>Periprosthetic infection after breast reconstruction is not uncommon and can result in loss of the implant pocket and negative patient outcomes. Management of these infections typically involves removal of the prosthesis, treatment with antibiotics, and delayed reconstruction upon infection resolution. The impact of adjunctive use of negative pressure wound therapy with instillation and dwell (NPWTi-d) on breast pocket salvage rates, time to implant reinsertion, and related outcomes was examined.</p><p><strong>Methods: </strong>A systematic literature search using PubMed, Cochrane, OVID, Scopus, and Embase was conducted to identify peer-reviewed articles written in English and published between January 2004 and April 2023 that examined NPWTi-d use in the breast pocket with a history of periprosthetic infection after breast reconstruction.</p><p><strong>Results: </strong>Of the 1703 publications, 6 studies met inclusion criteria, representing 115 patients and 122 breasts. The overall breast pocket salvage rate with NPWTi-d across studies was approximately 92%. In the 6 studies that included prosthesis type and radiation history, overall salvage rates were 97.8% (45 of 46) for pockets containing implants and 93.8% (15 of 16) for pockets containing tissue expanders. Salvage rates were 85.7% (12 of 14) and 91.7% (53 of 58) for irradiated and nonirradiated breasts, respectively. Mean time to implant reinsertion ranged from 2.3 to 10.3 days.</p><p><strong>Conclusions: </strong>In this review, antibiotic therapy along with adjunctive use of NPWTi-d for periprosthetic infections after breast reconstructions was associated with high rates of breast pocket salvage and reduced time to implant reinsertion. Larger prospective and randomized trials are needed to better understand and optimize the effectiveness of NPWTi-d in this population.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 11","pages":"e6267"},"PeriodicalIF":1.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-05eCollection Date: 2024-11-01DOI: 10.1097/GOX.0000000000006264
Hugo A Aguilar, Brian A Ramírez, Hector M Serrano, Silvia J Villabona, Alfredo E Hoyos, Agustina Varela
Background: Hyperbaric oxygen therapy (HBOT) increases oxygen concentration in affected tissues that enhance the cellular hypoxia recovery process, neovascularization, fibroblast proliferation, increased reactive oxygen species, suppression of proinflammatory states, and vascular compression. The aim of this article is to demonstrate the experience in the use of the hyperbaric chamber as an adjunctive management for the prompt recovery of patients who underwent aesthetic plastic surgery.
Methods: A retrospective descriptive study was conducted between 2021 and 2023, involving 296 patients who received HBOT after aesthetic surgical procedures, to demonstrate the recuperation time rate and the complication incidence in postoperative patients using HBOT.
Results: Most participants were women, with a median age of 33.5 years. Surgical procedures were grouped in liposculpture, abdominoplasty, and breast interventions. Complications related to the surgical event were low (10.7%), with occurrences of hematomas (n = 14, 4.72%), anemias (n = 9, 3.04%), and wound dehiscence (n = 8, 2.70%). There were no reports of surgical site infections or necrosis. Recovery times to get back to work were 10 days for liposuction, 3 days for breast interventions, and 21 days for abdominoplasty.
Conclusions: This study demonstrated the experience of using a postoperative hyperbaric chamber in aesthetic plastic surgery to promote recovery processes. The patient cohort in this study showed shortened recovery times than the data obtained from the major international plastic surgery organizations. Also, HBOT patients had a low complication rate, without infections, indicating the potential efficacy of this adjunctive therapy. Overall, this study underscores the promising role of hyperbaric chamber therapy in facilitating postoperative recovery and mitigating complications.
{"title":"Experience of Hyperbaric Chamber Usage in Aesthetic Plastic Surgery Practice for Recovery and Complication Prevention.","authors":"Hugo A Aguilar, Brian A Ramírez, Hector M Serrano, Silvia J Villabona, Alfredo E Hoyos, Agustina Varela","doi":"10.1097/GOX.0000000000006264","DOIUrl":"10.1097/GOX.0000000000006264","url":null,"abstract":"<p><strong>Background: </strong>Hyperbaric oxygen therapy (HBOT) increases oxygen concentration in affected tissues that enhance the cellular hypoxia recovery process, neovascularization, fibroblast proliferation, increased reactive oxygen species, suppression of proinflammatory states, and vascular compression. The aim of this article is to demonstrate the experience in the use of the hyperbaric chamber as an adjunctive management for the prompt recovery of patients who underwent aesthetic plastic surgery.</p><p><strong>Methods: </strong>A retrospective descriptive study was conducted between 2021 and 2023, involving 296 patients who received HBOT after aesthetic surgical procedures, to demonstrate the recuperation time rate and the complication incidence in postoperative patients using HBOT.</p><p><strong>Results: </strong>Most participants were women, with a median age of 33.5 years. Surgical procedures were grouped in liposculpture, abdominoplasty, and breast interventions. Complications related to the surgical event were low (10.7%), with occurrences of hematomas (n = 14, 4.72%), anemias (n = 9, 3.04%), and wound dehiscence (n = 8, 2.70%). There were no reports of surgical site infections or necrosis. Recovery times to get back to work were 10 days for liposuction, 3 days for breast interventions, and 21 days for abdominoplasty.</p><p><strong>Conclusions: </strong>This study demonstrated the experience of using a postoperative hyperbaric chamber in aesthetic plastic surgery to promote recovery processes. The patient cohort in this study showed shortened recovery times than the data obtained from the major international plastic surgery organizations. Also, HBOT patients had a low complication rate, without infections, indicating the potential efficacy of this adjunctive therapy. Overall, this study underscores the promising role of hyperbaric chamber therapy in facilitating postoperative recovery and mitigating complications.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 11","pages":"e6264"},"PeriodicalIF":1.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}