Pub Date : 2025-01-10eCollection Date: 2025-01-01DOI: 10.1097/GOX.0000000000006413
Damini Tandon, Arthur Sletten, Austin Ha, Gary B Skolnick, Paul Commean, Terence Myckatyn
We present an approach for evaluating abdominal computed tomography (CT) scans that generates reproducible measures relevant to donor site morbidity after abdominally based breast reconstruction. Seventeen preoperative CT metrics were measured in 20 patients with software: interanterior superior iliac spine distance; abdominal wall protrusion; interrectus distance; rectus abdominis width, thickness, and width-to-thickness ratio; abdominal wall thickness; subcutaneous fat volume; visceral fat volume; right/left psoas volumes and densities; and right/left rectus abdominis volumes and densities. Two operators performed measures to determine interrater reliability (n = 10). Interclass coefficients (ICCs) were calculated, and Bland-Altman plots were fashioned. Intrarater reliability was excellent (ICC > 0.9, 0.958-1) for 15 measures, and good (0.75 < ICC < 0.9, 0.815-0.853) for 2 measures. Interrater reliability was excellent (ICC > 0.9, 0.912-0.995) for 12 measures and good (0.75 < ICC < 0.9, 0.78-0.896) for 5 measures. Bland-Altman plots confirmed intra/interrater agreement. Our study meets its objective of establishing a protocol for obtaining abdominal CT measurements with high reproducibility and intrarater and interrater reliability. Although this study is not meant to weigh the particular influences of various CT measurements on clinical outcomes, we are now actively studying this with the intention of reporting our findings in the near future. Larger patient cohorts must be leveraged to determine correlations between abdominal CT scan findings and donor site outcomes using machine learning algorithms that generate models for predicting abdominal donor site complications.
{"title":"A Reproducible Method for Donor Site Computed Tomography Measurements in Abdominally Based Autologous Breast Reconstruction.","authors":"Damini Tandon, Arthur Sletten, Austin Ha, Gary B Skolnick, Paul Commean, Terence Myckatyn","doi":"10.1097/GOX.0000000000006413","DOIUrl":"10.1097/GOX.0000000000006413","url":null,"abstract":"<p><p>We present an approach for evaluating abdominal computed tomography (CT) scans that generates reproducible measures relevant to donor site morbidity after abdominally based breast reconstruction. Seventeen preoperative CT metrics were measured in 20 patients with software: interanterior superior iliac spine distance; abdominal wall protrusion; interrectus distance; rectus abdominis width, thickness, and width-to-thickness ratio; abdominal wall thickness; subcutaneous fat volume; visceral fat volume; right/left psoas volumes and densities; and right/left rectus abdominis volumes and densities. Two operators performed measures to determine interrater reliability (n = 10). Interclass coefficients (ICCs) were calculated, and Bland-Altman plots were fashioned. Intrarater reliability was excellent (ICC > 0.9, 0.958-1) for 15 measures, and good (0.75 < ICC < 0.9, 0.815-0.853) for 2 measures. Interrater reliability was excellent (ICC > 0.9, 0.912-0.995) for 12 measures and good (0.75 < ICC < 0.9, 0.78-0.896) for 5 measures. Bland-Altman plots confirmed intra/interrater agreement. Our study meets its objective of establishing a protocol for obtaining abdominal CT measurements with high reproducibility and intrarater and interrater reliability. Although this study is not meant to weigh the particular influences of various CT measurements on clinical outcomes, we are now actively studying this with the intention of reporting our findings in the near future. Larger patient cohorts must be leveraged to determine correlations between abdominal CT scan findings and donor site outcomes using machine learning algorithms that generate models for predicting abdominal donor site complications.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 1","pages":"e6413"},"PeriodicalIF":1.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10eCollection Date: 2025-01-01DOI: 10.1097/GOX.0000000000006421
Geng-Yi Yong, Alice Siew Ching Goh
{"title":"Embracing Diversity in Asian Facial Morphologies: Rethinking Terminology in Eyelid Surgery.","authors":"Geng-Yi Yong, Alice Siew Ching Goh","doi":"10.1097/GOX.0000000000006421","DOIUrl":"10.1097/GOX.0000000000006421","url":null,"abstract":"","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 1","pages":"e6421"},"PeriodicalIF":1.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10eCollection Date: 2025-01-01DOI: 10.1097/GOX.0000000000006424
Wen-Tsao Ho
Background: Radical surgery is the best treatment for axillary osmidrosis to eliminate the apocrine glands. However, marked postoperative hyperpigmentation may occur. Clinicians need an objective skin pigmentation examination to identify and treat hyperpigmentation. In this study, we aimed to use the Taylor Hyperpigmentation Scale (an objective visual scale) for evaluating long-term hyperpigmentation after osmidrosis surgery.
Methods: Twenty female patients with Fitzpatrick skin type III-IV who had undergone osmidrosis surgery were included in this study.
Results: The findings demonstrated that although there is an initial variation in the intensity of hyperpigmentation, in the majority of patients, there is a peak in hyperpigmentation between the third and sixth months after surgery. This is then followed by a gradual decline over the ensuing months. Some patients resolve hyperpigmentation completely, suggesting reversibility.
Conclusions: These results can help guide patient expectations and provide suitable postoperative management, thereby improving patient satisfaction and overall quality of life.
{"title":"An Objective Assessment of Long-term Postoperative Hyperpigmentation in Patients With Apocrine Gland-eliminated Osmidrosis Surgery.","authors":"Wen-Tsao Ho","doi":"10.1097/GOX.0000000000006424","DOIUrl":"10.1097/GOX.0000000000006424","url":null,"abstract":"<p><strong>Background: </strong>Radical surgery is the best treatment for axillary osmidrosis to eliminate the apocrine glands. However, marked postoperative hyperpigmentation may occur. Clinicians need an objective skin pigmentation examination to identify and treat hyperpigmentation. In this study, we aimed to use the Taylor Hyperpigmentation Scale (an objective visual scale) for evaluating long-term hyperpigmentation after osmidrosis surgery.</p><p><strong>Methods: </strong>Twenty female patients with Fitzpatrick skin type III-IV who had undergone osmidrosis surgery were included in this study.</p><p><strong>Results: </strong>The findings demonstrated that although there is an initial variation in the intensity of hyperpigmentation, in the majority of patients, there is a peak in hyperpigmentation between the third and sixth months after surgery. This is then followed by a gradual decline over the ensuing months. Some patients resolve hyperpigmentation completely, suggesting reversibility.</p><p><strong>Conclusions: </strong>These results can help guide patient expectations and provide suitable postoperative management, thereby improving patient satisfaction and overall quality of life.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 1","pages":"e6424"},"PeriodicalIF":1.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10eCollection Date: 2025-01-01DOI: 10.1097/GOX.0000000000006410
Michele Riccio, Angelica Aquinati, Mario Fordellone, Nicola Carboni, Andrea Marchesini, Francesco De Francesco
Background: The reconstruction of the nipple-areola complex (NAC) is a crucial step for completing breast restoration with patient satisfaction. Surgical reconstruction or tattooing of the NAC may not be preferable or feasible for some patients. There is no universal method for NAC that is ideal for every patient or clinical situation. Various approaches often do not maintain projection over time. Over time, several techniques have been perfected, including the C-V flap, to improve and support projection for patients with bilateral implant-based reconstructions.
Methods: We used, for the first time, prosthetic devices for NAC reconstruction and examined the safety of these devices associated with ease of implantation and patient satisfaction levels using a survey conducted during a 1-year follow-up. We enrolled 20 individuals who opted for these NAC prostheses following unilateral or bilateral breast reconstruction and following NAC excision.
Results: Ninety percent of the participants expressed satisfaction or high satisfaction with the appearance and balance of the new NAC. The prosthetics enhanced the overall body self-image and self-regard of all the study participants. Except for 4 patients, there were no reports of skin adverse reactions, infections, or erosion.
Conclusions: Encouraged by these auspicious outcomes that indicate a significant rate of safety and satisfaction, we believe that this straightforward, noninvasive, affordable medical device deserves consideration as a reconstructive option for all patients seeking breast reconstruction, promoting full body integrity.
{"title":"Innovations in Nipple-areolar Complex Reconstruction: Evaluation of a New Prosthesis.","authors":"Michele Riccio, Angelica Aquinati, Mario Fordellone, Nicola Carboni, Andrea Marchesini, Francesco De Francesco","doi":"10.1097/GOX.0000000000006410","DOIUrl":"10.1097/GOX.0000000000006410","url":null,"abstract":"<p><strong>Background: </strong>The reconstruction of the nipple-areola complex (NAC) is a crucial step for completing breast restoration with patient satisfaction. Surgical reconstruction or tattooing of the NAC may not be preferable or feasible for some patients. There is no universal method for NAC that is ideal for every patient or clinical situation. Various approaches often do not maintain projection over time. Over time, several techniques have been perfected, including the C-V flap, to improve and support projection for patients with bilateral implant-based reconstructions.</p><p><strong>Methods: </strong>We used, for the first time, prosthetic devices for NAC reconstruction and examined the safety of these devices associated with ease of implantation and patient satisfaction levels using a survey conducted during a 1-year follow-up. We enrolled 20 individuals who opted for these NAC prostheses following unilateral or bilateral breast reconstruction and following NAC excision.</p><p><strong>Results: </strong>Ninety percent of the participants expressed satisfaction or high satisfaction with the appearance and balance of the new NAC. The prosthetics enhanced the overall body self-image and self-regard of all the study participants. Except for 4 patients, there were no reports of skin adverse reactions, infections, or erosion.</p><p><strong>Conclusions: </strong>Encouraged by these auspicious outcomes that indicate a significant rate of safety and satisfaction, we believe that this straightforward, noninvasive, affordable medical device deserves consideration as a reconstructive option for all patients seeking breast reconstruction, promoting full body integrity.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 1","pages":"e6410"},"PeriodicalIF":1.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10eCollection Date: 2025-01-01DOI: 10.1097/GOX.0000000000006425
Gauthier Zinner, Jérôme Martineau, Giang Thanh Lam, Daniel Correia, Daniel F Kalbermatten, Carlo M Oranges
Background: Prepectoral (PP) immediate implant-based breast reconstruction (IBBR) is gaining popularity over the retropectoral (RP) breast reconstruction technique. This study aims to compare complication rates across different body mass index (BMI) groups in patients undergoing PP or RP IBBR.
Methods: A monocentric retrospective analysis was conducted on patients who underwent mastectomy and IBBR from January 2018 to December 2023. Preoperative characteristics, BMI, type of mastectomy procedure, PP or RR implant placement, and postoperative outcomes were collected and analyzed.
Results: A total of 217 patients were included, representing 276 IBBRs. The overall complication rate on a per breast basis was 26.4%. The overall complication rate did not differ across BMI groups (P = 0.314) and between PP and RP IBBR (P = 0.8083). In the PP group, anemia rate increased with low BMI (odds ratio [OR] 0.0215, P = 0.033) and skin complications were more frequent with higher BMI (OR 0.0428, P = 0.0389). In the RP group, higher BMI was correlated with a higher seroma rate in the RP IBBR group (OR 1.2045, P = 0.0334) and a longer hospital length of stay (coefficient 0.248, adjusted R² 0.082, SD 0.098, P = 0.014).
Conclusions: PP IBBR was associated with a significantly higher rate of anemia in patients with low BMI, and a significantly higher rate of skin complications in high BMI. RP IBBR was associated with higher seroma rate and longer hospital length of stay in patients with higher BMI.
背景:乳前(PP)即刻植入式乳房重建术(IBBR)正逐渐超越乳后(RP)乳房重建术。本研究旨在比较不同体重指数(BMI)组PP或RP IBBR患者的并发症发生率。方法:对2018年1月至2023年12月接受乳房切除术和IBBR的患者进行单中心回顾性分析。收集并分析术前特征、BMI、乳房切除术类型、PP或RR植入物放置以及术后结果。结果:共纳入217例患者,代表276例ibbr。每个乳房的总并发症发生率为26.4%。总体并发症发生率在BMI组间无差异(P = 0.314), PP组和RP组IBBR组间无差异(P = 0.8083)。在PP组中,BMI越低贫血发生率越高(比值比[OR] 0.0215, P = 0.033), BMI越高皮肤并发症发生率越高(比值比[OR] 0.0428, P = 0.0389)。在RP组中,较高的BMI与RP IBBR组较高的血肿率(OR 1.2045, P = 0.0334)和较长的住院时间相关(系数0.248,调整后R²0.082,SD 0.098, P = 0.014)。结论:PP IBBR与低BMI患者较高的贫血率和高BMI患者较高的皮肤并发症发生率相关。高BMI患者的RP IBBR与较高的血肿率和较长的住院时间相关。
{"title":"Postoperative Outcomes in Prepectoral Versus Retropectoral Immediate Implant-based Breast Reconstruction Across Body Mass Index Categories.","authors":"Gauthier Zinner, Jérôme Martineau, Giang Thanh Lam, Daniel Correia, Daniel F Kalbermatten, Carlo M Oranges","doi":"10.1097/GOX.0000000000006425","DOIUrl":"10.1097/GOX.0000000000006425","url":null,"abstract":"<p><strong>Background: </strong>Prepectoral (PP) immediate implant-based breast reconstruction (IBBR) is gaining popularity over the retropectoral (RP) breast reconstruction technique. This study aims to compare complication rates across different body mass index (BMI) groups in patients undergoing PP or RP IBBR.</p><p><strong>Methods: </strong>A monocentric retrospective analysis was conducted on patients who underwent mastectomy and IBBR from January 2018 to December 2023. Preoperative characteristics, BMI, type of mastectomy procedure, PP or RR implant placement, and postoperative outcomes were collected and analyzed.</p><p><strong>Results: </strong>A total of 217 patients were included, representing 276 IBBRs. The overall complication rate on a per breast basis was 26.4%. The overall complication rate did not differ across BMI groups (<i>P</i> = 0.314) and between PP and RP IBBR (<i>P</i> = 0.8083). In the PP group, anemia rate increased with low BMI (odds ratio [OR] 0.0215, <i>P</i> = 0.033) and skin complications were more frequent with higher BMI (OR 0.0428, <i>P</i> = 0.0389). In the RP group, higher BMI was correlated with a higher seroma rate in the RP IBBR group (OR 1.2045, <i>P</i> = 0.0334) and a longer hospital length of stay (coefficient 0.248, adjusted <i>R</i>² 0.082, SD 0.098, <i>P</i> = 0.014).</p><p><strong>Conclusions: </strong>PP IBBR was associated with a significantly higher rate of anemia in patients with low BMI, and a significantly higher rate of skin complications in high BMI. RP IBBR was associated with higher seroma rate and longer hospital length of stay in patients with higher BMI.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 1","pages":"e6425"},"PeriodicalIF":1.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10eCollection Date: 2025-01-01DOI: 10.1097/GOX.0000000000006459
Ahmad Saadya, Tarek El-Tantawy
Background: Social media platforms such as TikTok have recently emerged as influential tools for information dissemination, offering plastic surgeons new opportunities to promote their practices. However, these platforms also present significant challenges regarding online safety, ethical considerations, and the potential spread of misinformation.
Methods: This study analyzes the experience of gaining 100,000 followers on TikTok within 6 months, highlighting the excitement of rapid growth alongside the challenges posed by the potential for misinformation. We propose a strategic approach to leveraging social media effectively and ethically, focusing on storytelling, educational content, and audience engagement; highlighting unique selling propositions; utilizing analytics; and maintaining consistency. Ethical considerations in medical communication are also discussed, emphasizing the need for robust guidelines.
Results: From December 2023 to June 2024, the author posted 56 videos in Arabic, the target market's language. These videos garnered 16,566,900 views and 758,500 likes, with an average video length of 95.36 seconds. This growth led to a 47% increase in nonsurgical aesthetic consultations. Engagement and educational content, such as study tips, received the highest views, totaling 5.6 million, demonstrating the importance of such content in building a follower base for targeted marketing.
Conclusions: Our findings highlight the power and potential risks of social media in healthcare, advocating for a balanced approach that maximizes benefits while mitigating the spread of misinformation.
{"title":"Social Media Growth Blueprint for Plastic Surgeons: Insights and Considerations From Personal Experience.","authors":"Ahmad Saadya, Tarek El-Tantawy","doi":"10.1097/GOX.0000000000006459","DOIUrl":"10.1097/GOX.0000000000006459","url":null,"abstract":"<p><strong>Background: </strong>Social media platforms such as TikTok have recently emerged as influential tools for information dissemination, offering plastic surgeons new opportunities to promote their practices. However, these platforms also present significant challenges regarding online safety, ethical considerations, and the potential spread of misinformation.</p><p><strong>Methods: </strong>This study analyzes the experience of gaining 100,000 followers on TikTok within 6 months, highlighting the excitement of rapid growth alongside the challenges posed by the potential for misinformation. We propose a strategic approach to leveraging social media effectively and ethically, focusing on storytelling, educational content, and audience engagement; highlighting unique selling propositions; utilizing analytics; and maintaining consistency. Ethical considerations in medical communication are also discussed, emphasizing the need for robust guidelines.</p><p><strong>Results: </strong>From December 2023 to June 2024, the author posted 56 videos in Arabic, the target market's language. These videos garnered 16,566,900 views and 758,500 likes, with an average video length of 95.36 seconds. This growth led to a 47% increase in nonsurgical aesthetic consultations. Engagement and educational content, such as study tips, received the highest views, totaling 5.6 million, demonstrating the importance of such content in building a follower base for targeted marketing.</p><p><strong>Conclusions: </strong>Our findings highlight the power and potential risks of social media in healthcare, advocating for a balanced approach that maximizes benefits while mitigating the spread of misinformation.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 1","pages":"e6459"},"PeriodicalIF":1.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10eCollection Date: 2025-01-01DOI: 10.1097/GOX.0000000000006468
Edoardo Raposio, Alice Morello, Giorgio Raposio
The gluteal region has become a rising area of interest in plastic surgery in recent years, as reflected in body contouring surgery trends. In this study, the authors explain what the arrow effect consists of and how to highlight it during a Brazilian butt lift or a gluteal liposculpture: liposuction of the sacral triangle, fat grafting of the upper gluteal quadrants, liposuction of the dimples of Venus and of the midline superficially to the spinal column, and fat grafting of the erector spinae muscles.
{"title":"The \"Arrow Factor\" in Gluteoplasty and Brazilian Butt Lift.","authors":"Edoardo Raposio, Alice Morello, Giorgio Raposio","doi":"10.1097/GOX.0000000000006468","DOIUrl":"10.1097/GOX.0000000000006468","url":null,"abstract":"<p><p>The gluteal region has become a rising area of interest in plastic surgery in recent years, as reflected in body contouring surgery trends. In this study, the authors explain what the arrow effect consists of and how to highlight it during a Brazilian butt lift or a gluteal liposculpture: liposuction of the sacral triangle, fat grafting of the upper gluteal quadrants, liposuction of the dimples of Venus and of the midline superficially to the spinal column, and fat grafting of the erector spinae muscles.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 1","pages":"e6468"},"PeriodicalIF":1.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-26eCollection Date: 2024-12-01DOI: 10.1097/GOX.0000000000006401
Felipe Mesa, Oscar Leal, María Elena Ramos
Background: The Brunelli flap is an option in the reconstruction of the thumb after trauma or oncological resections. The arc of movement of the flap makes it possible to resolve defects in the proximal, palmar, dorsal, and lateral regions.
Methods: We present a case series of 11 patients in whom a Brunelli flap was performed for postoncological reconstruction, melanoma in situ, and invasive squamous cell carcinoma of the thumb nail unit associated with Mohs micrographic surgery. This combination has not been described before.
Results: The reconstruction was carried out using a Brunelli flap, incorporating certain variations to the original technique. Clinical follow-up was performed during a 1-year period. All flaps showed good viability. In 3 flaps, there was mild distal suffering that resolved with local healing. Three patients presented hypersensitivity in the distal part, which was managed with physical therapy. The functionality of the thumb was not altered in any case, and there were no complications in the donor site. No tumor recurrence was documented in any patient.
Conclusions: The use of the Brunelli flap to reconstruct the nail unit after an oncological resection with Mohs surgery is a good alternative. The advantages include a dorsal artery as a constant vessel and a homodigital flap that does not cause morbidity in the donor area, and with Mohs surgery, amputation is avoided. Disadvantages include lack of sensation of the flap. Some limitations of our study are the sample size and lack of long-term follow-up.
{"title":"Brunelli (Dorsoulnar) Flap for the Reconstruction of Defect of the Thumb Nail Unit After Oncological Resections With Mohs Micrographic Surgery.","authors":"Felipe Mesa, Oscar Leal, María Elena Ramos","doi":"10.1097/GOX.0000000000006401","DOIUrl":"10.1097/GOX.0000000000006401","url":null,"abstract":"<p><strong>Background: </strong>The Brunelli flap is an option in the reconstruction of the thumb after trauma or oncological resections. The arc of movement of the flap makes it possible to resolve defects in the proximal, palmar, dorsal, and lateral regions.</p><p><strong>Methods: </strong>We present a case series of 11 patients in whom a Brunelli flap was performed for postoncological reconstruction, melanoma in situ, and invasive squamous cell carcinoma of the thumb nail unit associated with Mohs micrographic surgery. This combination has not been described before.</p><p><strong>Results: </strong>The reconstruction was carried out using a Brunelli flap, incorporating certain variations to the original technique. Clinical follow-up was performed during a 1-year period. All flaps showed good viability. In 3 flaps, there was mild distal suffering that resolved with local healing. Three patients presented hypersensitivity in the distal part, which was managed with physical therapy. The functionality of the thumb was not altered in any case, and there were no complications in the donor site. No tumor recurrence was documented in any patient.</p><p><strong>Conclusions: </strong>The use of the Brunelli flap to reconstruct the nail unit after an oncological resection with Mohs surgery is a good alternative. The advantages include a dorsal artery as a constant vessel and a homodigital flap that does not cause morbidity in the donor area, and with Mohs surgery, amputation is avoided. Disadvantages include lack of sensation of the flap. Some limitations of our study are the sample size and lack of long-term follow-up.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 12","pages":"e6401"},"PeriodicalIF":1.5,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-26eCollection Date: 2024-12-01DOI: 10.1097/GOX.0000000000006404
Matthew J Regulski, Molly C Saunders, Sharron E McCulloch, Alla Danilkovitch
Background: Loss or displacement of a fat pad on the foot increases plantar pressure, leading to pain and plantar ulcers. These ulcers, especially in patients with diabetic neuropathy, have high recurrence rates, often resulting in amputations. Standard of care focuses on reducing plantar pressure with shoe padding or orthotic devices, leaving the restoration of the fat pad as an unmet medical need. To address this, a human cryopreserved adipose tissue (hCAT) allograft has been developed to repair adipose tissue defects.
Methods: Scientific characterization of hCAT included assessments of its structural properties, immunogenicity, persistence, and remodeling in both in vitro and in vivo models. The incidence of adverse events and ulcer recurrence was analyzed retrospectively in 12 patients with diabetic neuropathy with preulcerative lesions who received 1.5-3.0 mL subcutaneous hCAT implants in areas with fat pad defects.
Results: When implanted in patients, hCAT remained palpable at the implantation sites, and no ulcerations occurred for an average of 6.4 months (range, 2-10 months). No product-related adverse events have been recorded to date. Long-term follow-up for implanted patients is ongoing.
Conclusions: Use of hCAT seems to be safe and potentially beneficial for managing patients at risk for plantar ulcerations. Further studies are warranted to evaluate hCAT's potential to manage patients at high risk for plantar ulcer formation.
背景:足部脂肪垫的丢失或移位会增加足底压力,导致疼痛和足底溃疡。这些溃疡,特别是糖尿病神经病变患者,复发率高,常常导致截肢。标准护理侧重于用鞋垫或矫形装置减少足底压力,而将脂肪垫的修复作为未满足的医疗需求。为了解决这个问题,人类冷冻保存脂肪组织(hCAT)异体移植物已被开发用于修复脂肪组织缺陷。方法:hCAT的科学表征包括在体外和体内模型中评估其结构特性、免疫原性、持久性和重塑。回顾性分析12例伴有溃疡前病变的糖尿病神经病变患者在脂肪垫缺损区皮下植入1.5 ~ 3.0 mL hCAT的不良事件和溃疡复发的发生率。结果:患者植入后,hCAT在植入部位仍可触及,平均6.4个月(范围2-10个月)未发生溃疡。到目前为止,没有记录到与产品相关的不良事件。植入患者的长期随访正在进行中。结论:使用hCAT似乎是安全的,对管理有足底溃疡风险的患者可能有益。需要进一步的研究来评估hCAT治疗足底溃疡形成高风险患者的潜力。
{"title":"Pilot Study: Human Adipose Tissue Allograft for Fat Pad Defects in Patients With Preulcerative Lesions.","authors":"Matthew J Regulski, Molly C Saunders, Sharron E McCulloch, Alla Danilkovitch","doi":"10.1097/GOX.0000000000006404","DOIUrl":"10.1097/GOX.0000000000006404","url":null,"abstract":"<p><strong>Background: </strong>Loss or displacement of a fat pad on the foot increases plantar pressure, leading to pain and plantar ulcers. These ulcers, especially in patients with diabetic neuropathy, have high recurrence rates, often resulting in amputations. Standard of care focuses on reducing plantar pressure with shoe padding or orthotic devices, leaving the restoration of the fat pad as an unmet medical need. To address this, a human cryopreserved adipose tissue (hCAT) allograft has been developed to repair adipose tissue defects.</p><p><strong>Methods: </strong>Scientific characterization of hCAT included assessments of its structural properties, immunogenicity, persistence, and remodeling in both in vitro and in vivo models. The incidence of adverse events and ulcer recurrence was analyzed retrospectively in 12 patients with diabetic neuropathy with preulcerative lesions who received 1.5-3.0 mL subcutaneous hCAT implants in areas with fat pad defects.</p><p><strong>Results: </strong>When implanted in patients, hCAT remained palpable at the implantation sites, and no ulcerations occurred for an average of 6.4 months (range, 2-10 months). No product-related adverse events have been recorded to date. Long-term follow-up for implanted patients is ongoing.</p><p><strong>Conclusions: </strong>Use of hCAT seems to be safe and potentially beneficial for managing patients at risk for plantar ulcerations. Further studies are warranted to evaluate hCAT's potential to manage patients at high risk for plantar ulcer formation.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 12","pages":"e6404"},"PeriodicalIF":1.5,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-26eCollection Date: 2024-12-01DOI: 10.1097/GOX.0000000000006400
Mojgan Amiri, Renald Meçani, Christa D Niehot, Terri L Phillips, Katherine Goldie, Janina Kolb, Taulant Muka, Hua Daughtry
Background: Many studies assess aesthetic effectiveness of calcium hydroxylapatite (CaHA), with single-group designs as the most frequently applied designs in practice. This study systematically reviewed CaHA's effectiveness for aesthetic purposes among these studies.
Methods: A comprehensive search was conducted across 5 bibliographic databases. Single-group studies with at least 10 human adults were included. Summary measures of patients satisfaction and global aesthetic improvement scores were combined using the generalized linear mixed model. This systematic review adhered to the PRISMA reporting standards.
Results: Of 3131 records, 46 single-group studies, majority focused on facial areas (n = 32), were included for final qualitative analysis. A total number of 27 studies were included in the meta-analysis. Findings of the meta-analysis showed that 98% (95% confidence interval [CI], 91%-99%; I2, 0.0%) of patients were satisfied with the injection results in the facial area and 90% (95% CI, 67%-97%, I2, 35%) in other treated body areas. Also, patients reported 89% (95% CI, 76%-96%; I2, 65%) improvement on the global aesthetic improvement scale in facial areas and 94% (95% CI, 75%-99%; I2, 0.0%) in other treated regions. Similarly, investigators reported global aesthetic improvement in 92% of patients (95% CI, 33%-100%; I2, 92%) in facial areas and 95% (95% CI, 1%-100%; I2, 89%) in other treated areas.
Conclusions: Our findings showed aesthetic improvements and satisfaction following CaHA injections in both facial and nonfacial areas. However, studies focusing on nonfacial regions are limited. We recommend more rigorously designed trials to better understand CaHA's clinical effects.
{"title":"A Systematic Review and Meta-analysis of Single-group Studies Assessing the Role of Calcium Hydroxylapatite in Aesthetic Enhancements and Satisfaction.","authors":"Mojgan Amiri, Renald Meçani, Christa D Niehot, Terri L Phillips, Katherine Goldie, Janina Kolb, Taulant Muka, Hua Daughtry","doi":"10.1097/GOX.0000000000006400","DOIUrl":"10.1097/GOX.0000000000006400","url":null,"abstract":"<p><strong>Background: </strong>Many studies assess aesthetic effectiveness of calcium hydroxylapatite (CaHA), with single-group designs as the most frequently applied designs in practice. This study systematically reviewed CaHA's effectiveness for aesthetic purposes among these studies.</p><p><strong>Methods: </strong>A comprehensive search was conducted across 5 bibliographic databases. Single-group studies with at least 10 human adults were included. Summary measures of patients satisfaction and global aesthetic improvement scores were combined using the generalized linear mixed model. This systematic review adhered to the PRISMA reporting standards.</p><p><strong>Results: </strong>Of 3131 records, 46 single-group studies, majority focused on facial areas (n = 32), were included for final qualitative analysis. A total number of 27 studies were included in the meta-analysis. Findings of the meta-analysis showed that 98% (95% confidence interval [CI], 91%-99%; <i>I</i> <sup>2</sup>, 0.0%) of patients were satisfied with the injection results in the facial area and 90% (95% CI, 67%-97%, <i>I</i> <sup>2</sup>, 35%) in other treated body areas. Also, patients reported 89% (95% CI, 76%-96%; <i>I</i> <sup>2</sup>, 65%) improvement on the global aesthetic improvement scale in facial areas and 94% (95% CI, 75%-99%; <i>I</i> <sup>2</sup>, 0.0%) in other treated regions. Similarly, investigators reported global aesthetic improvement in 92% of patients (95% CI, 33%-100%; <i>I</i> <sup>2</sup>, 92%) in facial areas and 95% (95% CI, 1%-100%; <i>I</i> <sup>2</sup>, 89%) in other treated areas.</p><p><strong>Conclusions: </strong>Our findings showed aesthetic improvements and satisfaction following CaHA injections in both facial and nonfacial areas. However, studies focusing on nonfacial regions are limited. We recommend more rigorously designed trials to better understand CaHA's clinical effects.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"12 12","pages":"e6400"},"PeriodicalIF":1.5,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}