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Freehand Apple-peeling Technique for Recycled Skin Graft Harvesting in a Case of Buttock Hidradenitis Suppurativa. 徒手剥苹果术治疗臀部化脓性汗腺炎一例。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006469
Chen-Yu Ho, Keng-Yu Lin, Shu-Hung Huang

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder that often necessitates extensive surgery when medical treatment fails, particularly in advanced stages. Traditional surgical approaches, including flaps and skin grafts, are effective for tissue coverage but can lead to vascular complications and recurrence of HS. This study introduces a novel technique, the apple-peeling procedure, combined with negative pressure wound therapy at -50 mm Hg for 5 days postoperatively. This approach demonstrated improved operative efficiency and a low complication rate. Over a 3-year follow-up, there were no signs of HS recurrence, and the patient exhibited satisfactory functional and cosmetic outcomes. This technique may offer a promising alternative for treating HS, reducing the need for additional donor sites and mitigating the risks associated with conventional methods.

化脓性汗腺炎(HS)是一种慢性炎症性皮肤病,当药物治疗失败时,特别是在晚期,通常需要广泛的手术治疗。传统的手术方法,包括皮瓣和皮肤移植,对组织覆盖是有效的,但可能导致血管并发症和HS复发。本研究介绍了一种新颖的技术,即苹果去皮手术,并结合术后5天-50毫米汞柱负压伤口治疗。该方法提高了手术效率,并发症发生率低。在3年的随访中,没有HS复发的迹象,患者表现出令人满意的功能和美容结果。这项技术可能为治疗HS提供一种有希望的替代方法,减少了对额外供体部位的需求,并减轻了与传统方法相关的风险。
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引用次数: 0
Surgical Management of Gestational Gigantomastia: A Case Report Highlighting Therapeutic Intervention. 妊娠期巨乳症的外科治疗:一例强调治疗干预的报告。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006446
Misha A Lemma, Yisihak S Debodina, Martha F Gebremedhin, Meki K Aman, Don Eliseo Iii Lucero-Prisno

Gigantomastia is an exceedingly rare condition characterized by extraordinary growth of breasts during pregnancy, and its underlying etiology remains elusive. Although surgical intervention is the primary treatment modality, there have been emerging prospects for utilizing adjunctive medical therapies, such as bromocriptine, to address this challenging condition. Herein, we report the case of a 26-year-old woman who experienced abrupt and asymmetric bilateral breast enlargement commencing in the second month of her pregnancy. Remarkably, this enlargement persisted for an extended duration of 3 years. Despite the absence of prior medical therapy involving bromocriptine or other interventions, the patient ultimately underwent a simple mastectomy coupled with nipple-areola complex reconstruction. Although bromocriptine treatment holds potential benefits, its availability may vary in different healthcare settings. Therefore, the consideration of surgical management as an alternative approach becomes crucial, particularly when bromocriptine is not accessible or proves ineffective. This approach ensures the appropriate management of gestational gigantomastia, with the choice of treatment tailored to the individual patient's needs and resource availability.

巨乳症是一种极其罕见的疾病,其特征是在怀孕期间乳房的异常生长,其潜在的病因仍然难以捉摸。虽然手术干预是主要的治疗方式,但利用辅助药物治疗(如溴隐亭)来解决这一具有挑战性的疾病的前景正在出现。在此,我们报告的情况下,一位26岁的妇女谁经历了突然和不对称的双侧乳房增大开始在她怀孕的第二个月。值得注意的是,这种扩大持续了3年之久。尽管之前没有使用溴隐亭或其他药物治疗,但患者最终接受了简单的乳房切除术并进行了乳头乳晕复合体重建。虽然溴隐亭治疗具有潜在的益处,但其可用性在不同的医疗环境中可能有所不同。因此,考虑手术治疗作为一种替代方法变得至关重要,特别是当溴隐亭无法获得或证明无效时。这种方法确保适当的管理妊娠巨乳症,与治疗的选择量身定制的个别患者的需要和资源的可用性。
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引用次数: 0
Evaluating the Safety and Satisfaction of HYAcorp MLF2 for Noninvasive Buttock Augmentation: A Multicenter Study. 评价HYAcorp MLF2无创隆臀术的安全性和满意度:一项多中心研究。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006415
Piero Crabai, Luis Campos-Martínez, Francesco Marchetti, Fabio Fantozzi, Ruben Marques, Silvia Fontenete

Background: The increasing demand for noninvasive gluteal augmentation using hyaluronic acid (HA) gel highlights the need for research into its safety and effectiveness. This study aimed to assess the safety and satisfaction levels of patients and physicians regarding HA body filler for buttock enhancement. It also explores variations in outcomes across different injection sites and among different practitioners.

Methods: This retrospective, observational, descriptive multicenter study analyzed the outcomes of using a body HA filler (HYAcorp MLF2) for buttock augmentation across 4 Italian centers, with a 6-month follow-up period. Patients' and physicians' satisfaction levels were measured immediately postprocedure, and adverse events were monitored throughout the study period.

Results: Thirty-five subjects received injections, with an average volume of 85.1 ± 42.2 mL per subject injected. Throughout follow-up, 94% of patients and 100% of physicians rated the improvement as "very good" or "good." Adverse events were generally mild-to-moderate, typically resolving within 2-7 days. The most frequently recorded adverse effects were swelling, pain, and redness. No significant differences were observed among injectors (P > 0.05).

Conclusions: HYAcorp MLF2 is safe and effective for buttock augmentation, demonstrated by high satisfaction rates and manageable, mild-to-moderate adverse events, with no significant variation based on practitioner experience or clinic site.

背景:使用透明质酸(HA)凝胶进行无创臀肌增强的需求日益增加,这凸显了对其安全性和有效性研究的必要性。本研究的目的是评估病人和医生对HA体填充物丰臀的安全性和满意度。它还探讨了不同注射部位和不同医生之间结果的差异。方法:这项回顾性、观察性、描述性的多中心研究分析了4个意大利中心使用HA填充剂(HYAcorp MLF2)隆臀的结果,并进行了6个月的随访。在手术后立即测量患者和医生的满意度,并在整个研究期间监测不良事件。结果:35例患者接受注射,平均注射量为85.1±42.2 mL /例。在整个随访过程中,94%的患者和100%的医生将改善评价为“非常好”或“好”。不良事件一般为轻度至中度,通常在2-7天内消退。最常见的不良反应是肿胀、疼痛和发红。注射组间差异无统计学意义(P < 0.05)。结论:HYAcorp MLF2丰臀术安全有效,满意度高,可控制的轻至中度不良事件,且临床经验和临床地点无显著差异。
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引用次数: 0
A Threshold Technique Study to Understand Patient Preference for Smooth Versus Textured Breast Implants. 一项阈值技术研究了解患者对光滑与纹理乳房植入物的偏好。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006362
Dallas Wood, Peyton N Williams, Jessica E Thompson, Susana Peinado, Avery A Tilley, David Gebben, Jacqueline M Major, Jessica P Weinberg, Sung W Yoon, Michelle E Tarver

Background: Breast implant surfaces are categorized as smooth or textured. Compared with smooth implants, textured surface implants have a higher risk of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) but may have a lower risk of capsular contracture (CC). This study aimed to quantify whether survey respondents would be willing to accept a higher risk of BIA-ALCL in exchange for the potential reported benefits of textured breast implants.

Methods: We fielded a threshold technique survey to 405 respondents from 4 cohorts: (1) patients with breast cancer who were considering but did not receive reconstruction with implants, (2) patients with breast cancer who had received reconstruction with implants, (3) persons considering breast augmentation with implants, and (4) patients who had received breast augmentation with implants.

Results: The average maximum increase in the risk of BIA-ALCL that the survey respondents were willing to accept in exchange for textured implants-with both a teardrop-shaped option and a 10% reduction in the risk of CC-were as follows: 0.83% for patients who were considering breast reconstruction, 0.61% for patients who had received breast reconstruction, 0.85% for persons considering breast augmentation, and 0.60% for patients who had received breast augmentation.

Conclusions: We found respondents generally were willing to accept the higher risk of BIA-ALCL associated with textured implants to gain the potential benefit of reduced risk of CC and the option of the teardrop-shaped implant. Patient perspectives and preferences are integral, and continued assessment of patient perspectives can help inform regulatory and care paradigms.

背景:乳房植入物表面分为光滑和纹理。与光滑假体相比,纹理表面假体发生乳房假体相关间变性大细胞淋巴瘤(BIA-ALCL)的风险较高,但发生包膜挛缩(CC)的风险较低。本研究旨在量化调查对象是否愿意接受BIA-ALCL的高风险,以换取有纹理乳房植入物的潜在益处。方法:我们对来自4个队列的405名受访者进行了阈值技术调查:(1)正在考虑但未接受假体隆胸的乳腺癌患者,(2)接受过假体隆胸的乳腺癌患者,(3)正在考虑用假体隆胸的患者,(4)已经接受过假体隆胸的患者。结果:调查对象愿意接受的BIA-ALCL风险的平均最大增加幅度如下:考虑乳房重建的患者为0.83%,接受乳房重建的患者为0.61%,考虑隆胸的患者为0.85%,接受隆胸的患者为0.60%。结论:我们发现应答者普遍愿意接受与纹理种植体相关的更高风险的BIA-ALCL,以获得降低CC风险的潜在益处和泪滴状种植体的选择。患者的观点和偏好是不可分割的,对患者观点的持续评估有助于为监管和护理范例提供信息。
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引用次数: 0
Lateral Polydactyly of the Foot: Surgical Outcomes Based on a New Classification. 足外侧多指畸形:基于新分类的手术结果。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006463
Junko Otsuka, Emiko Horii, Shukuki Koh, Hiroki Takeshige

Background: The objective of this study was to propose a novel classification for lateral polydactyly of the foot that integrates both visual appearance and radiographic findings and to delineate surgical techniques and their outcomes based on this classification.

Methods: This study enrolled 148 feet from 126 patients who underwent initial surgery at our hospital between January 2009 and July 2021. The new classification system was derived from visual appearance according to the Hirase classification and radiological bifurcation level (D: distal or middle phalanx, P: proximal phalanx, and M: metatarsal). Incidence rates, surgical procedures, and surgical outcomes were compared across each type.

Results: Morphologically, 25 cases were classified as type A, 43 cases as type B1, and 80 cases as type B2. The branching level was categorized as D in 81 feet, P in 41 feet, and M in 26 feet, with 68 feet (46%) classified as B2-D type. Excision of the sixth toes was performed in all type A cases, whereas the majority of type B cases required excision of the fifth toes. Revision procedures were conducted on 8 feet. Three patients with type A-P classification developed painful hammer toe deformities as a late sequela that necessitated extensor tenolysis and metatarsophalangeal joint contracture release during their school-age years.

Conclusions: The classification system based on the combination of visual appearance and radiological branching level was both straightforward and beneficial for surgical planning and for predicting surgical outcomes and late sequelae.

背景:本研究的目的是为足侧多指畸形提出一种新的分类方法,结合视觉外观和影像学表现,并在此分类的基础上描述手术技术及其结果。方法:本研究招募了2009年1月至2021年7月期间在我院接受初次手术的126例患者中的148只脚。新的分类系统是根据Hirase分类和放射学分岔水平(D:远端或中指骨,P:近端指骨,M:跖骨)的视觉外观衍生的。比较了每种类型的发病率、手术方法和手术结果。结果:形态学上A型25例,B1型43例,B2型80例。分支等级分为D级(81英尺)、P级(41英尺)和M级(26英尺),其中68英尺(46%)为B2-D型。所有A型病例都切除了第六趾,而大多数B型病例需要切除第五趾。在8英尺上进行修正程序。3例a - p型患者出现了疼痛性锤状趾畸形,作为晚期后遗症,需要在学龄期间进行伸肌腱松解和跖趾关节挛缩松解。结论:基于视觉表现和放射分支水平相结合的分类系统简单明了,有利于手术计划和预测手术结果及后期后遗症。
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引用次数: 0
Reconstruction of Back Defect from Giant Congenital Melanocytic Nevus Using Dermal Substitute Matrix. 真皮替代基质重建巨大先天性黑素细胞痣背部缺损。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006487
Kareem W Makkawi, Paul T Beaineh, Saif E Emsieh, Edwin E Chrabieh, Amir E Ibrahim

Giant congenital melanocytic nevi are large pigmented premalignant lesions present at birth that have an associated risk of malignant transformation. Full-thickness excision of these lesions would be required to eliminate this risk. However, giant nevi can leave behind large defects that can be challenging to reconstruct. We present the case of a pediatric patient with a lesion occupying the entirety of the back, or around 18% total body surface area, and in whom Integra and meshed skin grafts were successfully used. This represents the largest defect size in the literature resulting from a giant nevus that has been treated by this method. Full take of the skin grafts was observed 26 days from the excision of the lesion with satisfactory functional outcomes.

巨大的先天性黑素细胞痣是出生时存在的大色素癌前病变,具有恶性转化的相关风险。需要对这些病变进行全层切除以消除这种风险。然而,巨大的痣可能会留下很大的缺陷,这对重建来说是一个挑战。我们报告了一个儿科患者的病例,病变占据了整个背部,或约18%的体表面积,并成功地使用了Integra和网状皮肤移植物。这是文献中使用这种方法治疗的巨大痣所导致的最大缺陷。病变切除后26天观察到皮肤移植完全恢复,功能结果令人满意。
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引用次数: 0
The Lipo-DIEP Flap Breast Reconstruction: A Valuable Innovation for Maximizing Abdominal Tissue Volume. 脂肪- diep皮瓣乳房重建:一个有价值的创新,以最大限度地提高腹部组织体积。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-17 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006445
Benedetto Longo, Gennaro D'Orsi, Alessio Farcomeni, Martina Giacalone, Elettra Gagliano, Lisa Vannucchi, Maximilian Catenacci, Gianluca Vanni, Claudio Oreste Buonomo, Valerio Cervelli

Background: The deep inferior epigastric perforator (DIEP) flap is universally considered the gold standard technique for breast reconstruction (BR), though it cannot always be proposed to patients with insufficient donor-site volume. We explore the efficacy of autologous fat transfer (AFT) of the Holm abdomen zone IV in the retropectoral plane during DIEP flap reconstruction (lipo-DIEP flap), to enhance the volume provided by the abdominal donor site in patients with low body mass index (BMI).

Methods: We prospectively enrolled patients with BMI less than 25 kg/m2 and candidates for lipo-DIEP flap BR (group A) comparing them with a control group (group B) undergoing traditional DIEP flap BR with the same characteristics of the first group (BMI < 25 kg/m2). Patients belonging to group A underwent magnetic resonance imaging preoperatively and 6 months after the BR, evaluating the adipose tissue volume retained in the retropectoral space.

Results: A total of 40 breasts were included in the study. The 2 groups were homogeneous regarding the collected variables, except for mean delayed AFT sessions (0.25 versus 0.95; P= 0.00094). The average volume of retropectoral AFT was 116.25 mL (SD 31.36). Six months after the procedure, the mean retropectoral fat volume calculated through magnetic resonance imaging was 48.64 mL (SD 14.15), whereas the mean graft integration rate was 45.98% (range, 30.7%-64.2%).

Conclusions: The lipo-DIEP flap is a valuable technique for patients with insufficient donor-site volume. Immediate retropectoral fat grafting from the Holm zone IV has proven to be safe in terms of complications, reducing the need for further AFT sessions.

背景:深下腹穿支皮瓣(DIEP)被普遍认为是乳房重建(BR)的金标准技术,尽管它并不总是被建议用于供体部位容量不足的患者。我们探讨在DIEP皮瓣重建(脂肪-DIEP皮瓣)过程中,在Holm腹部第四区逆行自体脂肪移植(AFT)的效果,以提高低体重指数(BMI)患者腹部供区提供的体积。方法:前瞻性招募BMI小于25 kg/m2的脂肪-DIEP皮瓣BR候选者(A组)与接受与第一组(BMI < 25 kg/m2)相同特征的传统DIEP皮瓣BR的对照组(B组)进行比较。A组患者术前及术后6个月行磁共振成像,评估逆行间隙内保留的脂肪组织体积。结果:共纳入40个乳房。两组所收集的变量均相同,除了平均延迟AFT时间(0.25 vs 0.95;P = 0.00094)。逆行性AFT平均体积116.25 mL (SD 31.36)。术后6个月,通过磁共振成像计算的平均逆行性脂肪体积为48.64 mL (SD 14.15),而平均移植物整合率为45.98%(范围30.7%-64.2%)。结论:对于供区容量不足的患者,脂肪- diep皮瓣是一种有价值的技术。从Holm IV区立即逆行脂肪移植术已被证明在并发症方面是安全的,减少了进一步AFT治疗的需要。
{"title":"The Lipo-DIEP Flap Breast Reconstruction: A Valuable Innovation for Maximizing Abdominal Tissue Volume.","authors":"Benedetto Longo, Gennaro D'Orsi, Alessio Farcomeni, Martina Giacalone, Elettra Gagliano, Lisa Vannucchi, Maximilian Catenacci, Gianluca Vanni, Claudio Oreste Buonomo, Valerio Cervelli","doi":"10.1097/GOX.0000000000006445","DOIUrl":"https://doi.org/10.1097/GOX.0000000000006445","url":null,"abstract":"<p><strong>Background: </strong>The deep inferior epigastric perforator (DIEP) flap is universally considered the gold standard technique for breast reconstruction (BR), though it cannot always be proposed to patients with insufficient donor-site volume. We explore the efficacy of autologous fat transfer (AFT) of the Holm abdomen zone IV in the retropectoral plane during DIEP flap reconstruction (lipo-DIEP flap), to enhance the volume provided by the abdominal donor site in patients with low body mass index (BMI).</p><p><strong>Methods: </strong>We prospectively enrolled patients with BMI less than 25 kg/m<sup>2</sup> and candidates for lipo-DIEP flap BR (group A) comparing them with a control group (group B) undergoing traditional DIEP flap BR with the same characteristics of the first group (BMI < 25 kg/m<sup>2</sup>). Patients belonging to group A underwent magnetic resonance imaging preoperatively and 6 months after the BR, evaluating the adipose tissue volume retained in the retropectoral space.</p><p><strong>Results: </strong>A total of 40 breasts were included in the study. The 2 groups were homogeneous regarding the collected variables, except for mean delayed AFT sessions (0.25 versus 0.95; <i>P</i>= 0.00094). The average volume of retropectoral AFT was 116.25 mL (SD 31.36). Six months after the procedure, the mean retropectoral fat volume calculated through magnetic resonance imaging was 48.64 mL (SD 14.15), whereas the mean graft integration rate was 45.98% (range, 30.7%-64.2%).</p><p><strong>Conclusions: </strong>The lipo-DIEP flap is a valuable technique for patients with insufficient donor-site volume. Immediate retropectoral fat grafting from the Holm zone IV has proven to be safe in terms of complications, reducing the need for further AFT sessions.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 1","pages":"e6445"},"PeriodicalIF":1.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11741219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pygopagus Twins Separation Using a Rectangular Fasciocutaneous Flap: Case Report From Beirut, Lebanon. 用矩形筋膜皮瓣分离双生子:黎巴嫩贝鲁特1例报告。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-17 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006478
Christopher Hakim, Saif Emsieh, Edwin Chrabieh, Jana Zeineddine, Amir Ibrahim

Conjoined twins, although rare, present unique challenges in surgical management, particularly regarding skin closure after separation. This case report details the successful separation of pygopagus conjoined twins using a rectangular skin flap technique. The twins, joined at the lumbar and sacral regions, underwent meticulous preoperative planning and collaborative effort from multiple medical teams. The surgery involved raising fasciocutaneous rectangular flaps over the buttocks, spine separation, rectal division, and reconstruction of pelvic floor muscles. The primary skin closure was achieved successfully. This case highlights the superior gluteal-based rectangular flap technique in such a separation and the importance of multidisciplinary approaches in improving outcomes for complex surgeries.

连体双胞胎虽然罕见,但在手术处理方面存在独特的挑战,特别是在分离后皮肤闭合方面。本病例报告详细介绍了使用矩形皮瓣技术成功分离pygopagus连体双胞胎。这对双胞胎在腰椎和骶骨部位连在一起,经过了精心的术前计划和多个医疗团队的共同努力。手术包括在臀部上提起筋膜矩形皮瓣、脊柱分离、直肠分离和骨盆底肌肉重建。初步皮肤闭合成功。本病例强调了基于臀上的矩形皮瓣技术在这种分离中的重要性,以及多学科方法在改善复杂手术结果中的重要性。
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引用次数: 0
Novel Frostbite Cooling Device for Real-time Assessment and Prevention of Chemotherapy-induced Peripheral Neuropathy. 用于实时评估和预防化疗引起的周围神经病变的新型冻伤冷却装置。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-17 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006423
Yuki Matsui, Hirotaka Kishi, Chihiro Matsui, Jun Morita, Hiroshi Mizuno, Hatan Mortada, Haruaki Sasaki, Takashi Fukagai

Background: Chemotherapy-induced peripheral neuropathy (CIPN) affects 29%-68% of patients undergoing anticancer treatments within the first month. Traditional cryotherapy methods, such as frozen gloves, can pose risks. This study evaluates the cool-water electric circulation seat (CECS), which maintains a constant 15°C, as a safer alternative.

Methods: In this prospective study, 21 healthy Japanese adults underwent 2.5 hours of hand cooling at 15°C, reflecting the standard duration of taxane anticancer drug administration. Microcirculation was evaluated using videocapillaroscopy before and after cooling.

Results: Results showed significant reductions in blood vessel area and altered red blood cell movement postcooling. Finger temperature and vascular area decreased significantly (P < 0.001), and red blood cell movement changed significantly, with most cells shifting from slow (52.4%) or fast (47.6%) movement before cooling to slow (23.8%) or immobile (76.2%) afterward (P < 0.001). Thirty minutes postcooling, 38.1% of participants reported temporary redness, and 28.6% reported pain, both resolving by the next day.

Conclusions: The CECS effectively provides secure cooling, offering a promising approach for CIPN prevention without frostbite risk. These findings highlight the potential advantages of CECS in sustained cooling therapy for CIPN prevention.

背景:化疗引起的周围神经病变(CIPN)影响29%-68%接受抗癌治疗的患者在第一个月内。传统的冷冻治疗方法,如冷冻手套,可能会带来风险。本研究评估了冷却水电动循环座椅(CECS)作为一种更安全的替代方案,该座椅保持恒定的15°C。方法:在这项前瞻性研究中,21名健康的日本成年人在15°C下进行2.5小时的手部冷却,这反映了紫杉烷类抗癌药物的标准服用时间。冷却前后用视频毛细管镜观察微循环。结果:结果显示冷却后血管面积明显减少,红细胞运动改变。手指温度和血管面积明显降低(P < 0.001),红细胞运动发生明显变化,大多数细胞从冷却前的缓慢(52.4%)或快速(47.6%)运动转变为冷却后的缓慢(23.8%)或不运动(76.2%)(P < 0.001)。冷却30分钟后,38.1%的参与者报告暂时发红,28.6%的参与者报告疼痛,两者都在第二天消退。结论:CECS有效地提供了安全的冷却,为CIPN预防提供了有前途的方法,没有冻伤风险。这些发现强调了CECS在持续冷却治疗预防CIPN方面的潜在优势。
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引用次数: 0
Recalcitrant Bilateral Volar Hand Burn Contracture in a Toddler Treated With Integra and Staged Full-thickness Skin Graft: A Literature Review. 顽固性双侧掌侧烧伤挛缩在幼儿治疗完整和分期全层皮肤移植:文献综述。
IF 1.5 Q3 SURGERY Pub Date : 2025-01-17 eCollection Date: 2025-01-01 DOI: 10.1097/GOX.0000000000006430
James C Yuen, Jennifer L Wallace, Susan C Steelman

Background: Recurrent burn contractures on the volar aspect of the hand present a formidable challenge, especially in the pediatric patient. We used Integra followed by staged full-thickness skin grafting for recurrent bilateral volar hand burn contracture in a toddler. We reviewed the literature to appraise the utility of full-thickness skin graft (FTSG) combined with Integra used for volar hand contractures.

Methods: A systematic review of the world's literature was conducted identifying publications on the application of Integra and skin substitutes for palmar hand contractures and wounds, to include burn injuries. We describe a case of a pediatric patient with recurrent bilateral burn flexion contracture of the palm and digits treated with scar excision and application of Integra, followed by staged application of FTSG.

Results: We identified 92 publications pertaining to volar hand defects or contractures managed with skin grafts, skin substitutes, and/or flaps. Ten articles referred to the use of Integra on volar hand wounds or contractures, and only 2 articles used FTSG instead of split-thickness skin graft in combination with Integra. Our systematic review of volar burn injuries of the hand and fingers demonstrated that the use of Integra combined with FTSG for postburn flexion contracture of the hand has not been previously reported.

Conclusions: This case report suggests that application of FTSG instead of split-thickness skin graft to vascularized Integra offers protective value against recurrent burn contracture of the palmar hand, but more studies are needed to support our hypothesis.

背景:手部掌侧的复发性烧伤挛缩是一个巨大的挑战,特别是在儿科患者中。我们采用Integra后分阶段全层皮肤移植治疗复发性双侧掌侧挛缩。我们回顾了文献来评估全层皮肤移植联合Integra治疗掌侧挛缩的有效性。方法:对世界文献进行系统回顾,确定Integra和皮肤替代品用于手掌挛缩和伤口的出版物,包括烧伤。我们描述了一个病例的儿科患者复发性双侧烧伤屈曲挛缩的手掌和手指治疗疤痕切除和应用Integra,然后分阶段应用FTSG。结果:我们确定了92篇关于用皮肤移植、皮肤替代物和/或皮瓣治疗掌侧缺损或挛缩的出版物。10篇文章报道了Integra在掌侧伤口或挛缩上的应用,只有2篇文章使用了FTSG代替裂厚皮移植联合Integra。我们对手掌和手指掌侧烧伤的系统回顾表明,使用Integra联合FTSG治疗烧伤后手部屈曲挛缩尚未有报道。结论:本病例报告表明,应用FTSG代替裂厚皮肤移植血管化的Integra对手掌复发性烧伤挛缩有保护作用,但需要更多的研究来支持我们的假设。
{"title":"Recalcitrant Bilateral Volar Hand Burn Contracture in a Toddler Treated With Integra and Staged Full-thickness Skin Graft: A Literature Review.","authors":"James C Yuen, Jennifer L Wallace, Susan C Steelman","doi":"10.1097/GOX.0000000000006430","DOIUrl":"https://doi.org/10.1097/GOX.0000000000006430","url":null,"abstract":"<p><strong>Background: </strong>Recurrent burn contractures on the volar aspect of the hand present a formidable challenge, especially in the pediatric patient. We used Integra followed by staged full-thickness skin grafting for recurrent bilateral volar hand burn contracture in a toddler. We reviewed the literature to appraise the utility of full-thickness skin graft (FTSG) combined with Integra used for volar hand contractures.</p><p><strong>Methods: </strong>A systematic review of the world's literature was conducted identifying publications on the application of Integra and skin substitutes for palmar hand contractures and wounds, to include burn injuries. We describe a case of a pediatric patient with recurrent bilateral burn flexion contracture of the palm and digits treated with scar excision and application of Integra, followed by staged application of FTSG.</p><p><strong>Results: </strong>We identified 92 publications pertaining to volar hand defects or contractures managed with skin grafts, skin substitutes, and/or flaps. Ten articles referred to the use of Integra on volar hand wounds or contractures, and only 2 articles used FTSG instead of split-thickness skin graft in combination with Integra. Our systematic review of volar burn injuries of the hand and fingers demonstrated that the use of Integra combined with FTSG for postburn flexion contracture of the hand has not been previously reported.</p><p><strong>Conclusions: </strong>This case report suggests that application of FTSG instead of split-thickness skin graft to vascularized Integra offers protective value against recurrent burn contracture of the palmar hand, but more studies are needed to support our hypothesis.</p>","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 1","pages":"e6430"},"PeriodicalIF":1.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11741221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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