Kamran Ranjbar, A. Molazadeh, A. Dakhili Ardestani, Mohammad Soleimanian, Zakaria Meshkibaf, M. Meshkibaf
{"title":"Antinociceptive and antioxidant effects of Onosma platyphyllum riedl extract","authors":"Kamran Ranjbar, A. Molazadeh, A. Dakhili Ardestani, Mohammad Soleimanian, Zakaria Meshkibaf, M. Meshkibaf","doi":"10.52547/phypha.26.4.10","DOIUrl":"https://doi.org/10.52547/phypha.26.4.10","url":null,"abstract":"","PeriodicalId":20151,"journal":{"name":"Physiology and Pharmacology","volume":"44 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74204156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Farhadi, M. Esmailidehaj, M. Rezvani, Mohammad Shahbazian, Faezeh Jafary, Mohammad Amin Ghafari, Jalil Alizade, H. Azizian
{"title":"A review of the Effects of 17 β-Estradiol on Endoplasmic Reticulum Stress: Mechanisms and Pathway","authors":"Z. Farhadi, M. Esmailidehaj, M. Rezvani, Mohammad Shahbazian, Faezeh Jafary, Mohammad Amin Ghafari, Jalil Alizade, H. Azizian","doi":"10.52547/phypha.26.3.1","DOIUrl":"https://doi.org/10.52547/phypha.26.3.1","url":null,"abstract":"","PeriodicalId":20151,"journal":{"name":"Physiology and Pharmacology","volume":"12 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72949976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Metabolic syndrome (MetS) occurs as co-morbidity in chronic obstructive pulmonary disease (COPD) and requires evaluation. Methods: MetS was studied in 336 patients of COPD (NCP-ATP III guidelines). TNF-α, IL-6 and C reactive protein were analysed. Patients were divided into metabolic (n=89) and non-MetS (n=247) groups and further divided into mild to very severe COPD category as per Global Initiative for Chronic Obstructive Lung Disease. Results: The 89 patients (26.49%) had MetS. Waist hip ratio (WHR) was more in 80.89% (72/89). Triglycerides and HDL derangements were found in 63 and 75 patients. Fasting blood glucose, systolic and diastolic blood pressure criterion were met by 58 (65.17 %), 20 (22.47%) and 32 (35.95%) patients respectively. In non-MetS group, the derangement in above parameters were found in 41, 53, 109, 47, 43 and 46 patients respectively. Compared to MetS group, significant difference was found in WHR, lipid profile and blood pressure. Significant difference was found in waist circumference, triglycerides, HDL, fasting blood glucose and diastolic blood pressure between COPD groups with and without MetS. Moderate COPD patients had highest MetS. Difference in results as per severity of disease was found to be non-significant. Inflammatory markers between COPD groups with and without MetS were non-significant with levels more in latter group. Within COPD group (as per severity of disease) with MetS their levels were significantly raised. Conclusion: MetS occurs as co-morbidity in COPD and requires evaluation which will help in better management and prevent cardio metabolic complications.
{"title":"A study of metabolic syndrome in chronic obstructive pulmonary disease patients attending out-patient department of a medical college","authors":"S. Waseem, N. Islam","doi":"10.32598/PPJ.25.2.10","DOIUrl":"https://doi.org/10.32598/PPJ.25.2.10","url":null,"abstract":"Introduction: Metabolic syndrome (MetS) occurs as co-morbidity in chronic obstructive pulmonary disease (COPD) and requires evaluation. Methods: MetS was studied in 336 patients of COPD (NCP-ATP III guidelines). TNF-α, IL-6 and C reactive protein were analysed. Patients were divided into metabolic (n=89) and non-MetS (n=247) groups and further divided into mild to very severe COPD category as per Global Initiative for Chronic Obstructive Lung Disease. Results: The 89 patients (26.49%) had MetS. Waist hip ratio (WHR) was more in 80.89% (72/89). Triglycerides and HDL derangements were found in 63 and 75 patients. Fasting blood glucose, systolic and diastolic blood pressure criterion were met by 58 (65.17 %), 20 (22.47%) and 32 (35.95%) patients respectively. In non-MetS group, the derangement in above parameters were found in 41, 53, 109, 47, 43 and 46 patients respectively. Compared to MetS group, significant difference was found in WHR, lipid profile and blood pressure. Significant difference was found in waist circumference, triglycerides, HDL, fasting blood glucose and diastolic blood pressure between COPD groups with and without MetS. Moderate COPD patients had highest MetS. Difference in results as per severity of disease was found to be non-significant. Inflammatory markers between COPD groups with and without MetS were non-significant with levels more in latter group. Within COPD group (as per severity of disease) with MetS their levels were significantly raised. Conclusion: MetS occurs as co-morbidity in COPD and requires evaluation which will help in better management and prevent cardio metabolic complications.","PeriodicalId":20151,"journal":{"name":"Physiology and Pharmacology","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91042724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Pazhoohan, Fatemeh Abbasi Feijani, Farnaz Mehrabbeigi, M. Palizvan, Saeed Hajihashemi
{"title":"Effect of nasal airflow on respiratory pattern variability in rats","authors":"S. Pazhoohan, Fatemeh Abbasi Feijani, Farnaz Mehrabbeigi, M. Palizvan, Saeed Hajihashemi","doi":"10.52547/phypha.26.1.7","DOIUrl":"https://doi.org/10.52547/phypha.26.1.7","url":null,"abstract":"","PeriodicalId":20151,"journal":{"name":"Physiology and Pharmacology","volume":"19 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87246051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Interactive effect of Berberine Chloride and exercise rehabilitation on lung tissue apoptosis and oxidative stress biomarkers in rats exposed to Diazinon","authors":"Reza Niazi, M. Peeri, M. Azarbayjani","doi":"10.52547/phypha.26.1.2","DOIUrl":"https://doi.org/10.52547/phypha.26.1.2","url":null,"abstract":"","PeriodicalId":20151,"journal":{"name":"Physiology and Pharmacology","volume":"40 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87309036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amirhossein Maghsoudi, J. Zaringhalam, M. Moosavi, A. Eidi
{"title":"Intraperitoneal Carbamylated erythropoietin improves memory and hippocampal apoptosis in beta amyloid rat model of Alzheimer’s disease through stimulating autophagy and inhibiting necroptosis","authors":"Amirhossein Maghsoudi, J. Zaringhalam, M. Moosavi, A. Eidi","doi":"10.52547/phypha.26.4.1","DOIUrl":"https://doi.org/10.52547/phypha.26.4.1","url":null,"abstract":"","PeriodicalId":20151,"journal":{"name":"Physiology and Pharmacology","volume":"42 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77733576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic effects of Nigella sativa on asthma, a systematic review of clinical trial","authors":"M. Khazdair, Alireza Amirabadizadeh","doi":"10.52547/phypha.26.2.2","DOIUrl":"https://doi.org/10.52547/phypha.26.2.2","url":null,"abstract":"","PeriodicalId":20151,"journal":{"name":"Physiology and Pharmacology","volume":"102 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79386750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fresh palm oil improves impaired renal function in phenylhydrazine-induced anaemic Wistar rats via its anti-anaemic effect and modulation of expressions of pro-oxidant/antioxidants, inflammatory cytokines and caspase-3 in the kidneys.","authors":"Ernest Atelhe Amama, Augustine Lishilinimye Udefa, Favour Nyoh Beshel, Efiok Aniekan Archibong, S. Okpa, Justina Nwandimma Nwangwa, Ndianabasi Isidore Felix, Godwin Akronyi","doi":"10.52547/phypha.26.3.8","DOIUrl":"https://doi.org/10.52547/phypha.26.3.8","url":null,"abstract":"","PeriodicalId":20151,"journal":{"name":"Physiology and Pharmacology","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90680660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Which pharmaceutical agent is most commonly used for suicide? An epidemiological investigation in Loghman Hakim Hospital, 2018 - 2019","authors":"Masoumeh Haji, Mitra Rahimi, K. Joharchi","doi":"10.52547/phypha.27.1.13","DOIUrl":"https://doi.org/10.52547/phypha.27.1.13","url":null,"abstract":"","PeriodicalId":20151,"journal":{"name":"Physiology and Pharmacology","volume":"40 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76202440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic effects of exercise, escitalopram, and exercise-accompanied escitalopram on brain functions in rats with depression","authors":"Mahshid Zamani, M. Radahmadi, Parham Reisi","doi":"10.52547/phypha.26.2.7","DOIUrl":"https://doi.org/10.52547/phypha.26.2.7","url":null,"abstract":"","PeriodicalId":20151,"journal":{"name":"Physiology and Pharmacology","volume":"39 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76647037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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