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Effect of extensive resection of small intestine on the enterochromaffin cells of the remaining intestinal segment. 广泛切除小肠对剩余肠段肠色素细胞的影响。
M Drews, M Gawroński

The authors discuss the problem of quantitative changes in enterochromaffin cells in the rat small intestine after its extensive resection. An increase was found in the number of these cells in the peripheral part of the intestine 4 to 8 weeks after the operation. These quantitative changes are explained by the regenerative activity in this period.

作者讨论了大鼠小肠广泛切除后肠染色质细胞的定量变化问题。术后4 ~ 8周,小肠外周细胞数量明显增加。这些数量变化可以用这一时期的再生活动来解释。
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引用次数: 0
Centenary of the discovery of the typhoid bacillus by Tadeusz Browiez. 塔德乌什·布罗维兹发现伤寒杆菌一百周年纪念。
S Wajs
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引用次数: 0
Gastrointestinal changes in patients with hypogammaglobulinemia. 低丙种球蛋白血症患者的胃肠道改变。
S Horoszek-Maziarz, A Kryszewski, J Lehman-Borowska, H Rynkiewicz, I Bardzik, B Krupa-Wojciechowska

Three cases of hypogammaglobulinemia are described. In all cases the first symptoms of disease manifesting as pneumonia were preceded by diarrhea. In gastric biopsy there was atrophic gastritis with lack of plasmocytes. All patients demonstrated gastric achylia and symptoms of malabsorption syndrome. The causes of gastrointestinal changes, most probably infections, with simultaneous defective mucosal barrier are discussed.

本文报道三例低丙种球蛋白血症。在所有病例中,首先表现为肺炎的疾病症状均先于腹泻。胃活检显示萎缩性胃炎伴浆细胞缺乏。所有患者均表现为胃achylia和吸收不良综合征。胃肠道变化的原因,最可能是感染,同时有缺陷的粘膜屏障进行了讨论。
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引用次数: 0
Studies on the behavior of lymphocytes in the direct lymphocytotoxicity test (DLT) in surgical patients: II. Dynamics of immunological reactivity in selected cases. 外科患者直接淋巴细胞毒性试验(DLT)中淋巴细胞行为的研究:II。选定病例的免疫反应动力学。
L Cybulski, G Turowski, M Zubel

The results of investigations on the dynamics of immune reactivity are presented in 6 cases selected from 38 surgical patients. The investigations were carried out during surgical treatment of peripheral arterial diseases, malignant neoplasms of the alimentary tract, and extensive chronic inflammatory processes of the soft tissues. The evaluation of immune reactivity of these patients was based on the results of the direct lymphocytotoxicity test (DLT), the intensity of the autolymphocytotoxic reactions in the cold (15 degrees C) test, morphology and other changes of lymphocytes (various forms, lysis, leukergy) and on their ability to undergo blastic transformation in vitro after stimulation with PHA. The joint evaluation of investigations carried out repeatedly in these diseases may be useful for tracing the dynamics of immune reactivity in surgical patients.

本文报道了38例外科手术患者中6例免疫反应动力学的研究结果。调查是在手术治疗外周动脉疾病、消化道恶性肿瘤和软组织广泛的慢性炎症过程中进行的。这些患者的免疫反应性评价是基于直接淋巴细胞毒性试验(DLT)的结果,冷(15℃)试验中自身淋巴细胞毒性反应的强度,淋巴细胞的形态和其他变化(各种形式,裂解,白血病)以及它们在PHA刺激后体外进行胚性转化的能力。在这些疾病中反复进行的联合评估调查可能有助于追踪手术患者的免疫反应动力学。
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引用次数: 0
Observations on polycythemia vera turning into acute or chronic granulocytic leukemia during treatment with radioactive phosphorus 32P. 放射性磷32P治疗真性红细胞增多症转为急慢性粒细胞白血病的观察。
W Krańik

In a group of 172 cases of polycythemia vera treated with radioactive phosphorus acute granulocytic leukemia developed in 3 and chronic granulocytic leukemia in 6 cases. The author believes that development of acute granulocytic leukemia during this treatment may be considered with some probability as a result of the leukemia-inducing action of ionizing radiation. Transition of polycythemia vera into chronic granulocytic leukemia seems to be a natural outcome of this complex myeloproliferative syndrome in patients with survival prolonged by treatment with 32P.

放射性磷治疗真性红细胞增多症172例,急性粒细胞性白血病3例,慢性粒细胞性白血病6例。作者认为,在此治疗过程中,有可能由于电离辐射的致白血病作用而导致急性粒细胞白血病的发生。真性红细胞增多症转变为慢性粒细胞白血病似乎是这种复杂骨髓增生综合征在32P治疗后延长生存期的患者的自然结果。
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引用次数: 0
The course of treatment in schizophrenia in relation to the presence of affective disturbances. 精神分裂症的治疗过程与情感障碍的存在有关。
J Jaroszyński, M Rzewuska-Szatkowska, J Skowrońska, K Tarczyńska

The frequency and type of affective disturbances developing in schizophrenia were evaluated and their relationship to the course of the disease and results of treatment was analyzed. The studied material comprised 67 patients with the diagnosis of schizophrenia, treated in hospital in 1973. The depressive and paranoid scores of Jaroszyński were used for evaluation of patients. Affective disturbances were found in nearly all cases, depressive symptoms being most frequent. The development or increasing intensity of depression could only partly be attributed to the action of neuroleptic drugs. No difference was found in the clinical pattern of affective distrubances between paranoid and cyclic schizophrenia. In the paranoid-depressive syndromes the best therapeutic results were obtained in cases with decreased complex activities and psychic inhibition. Neuroleptic drugs possessing some thymoleptic properties were used in treatment of these cases, sometimes in combination with tricyclic antidepressants. The results were in cases with significant anxiety, inhibition and depressive attitude towards the prevailing situation. Paranoid productive symptoms appeared in this group sometimes during treatment with tricyclic antidepressants.

评估精神分裂症中发生情感性障碍的频率和类型,并分析其与病程和治疗结果的关系。研究对象包括1973年在医院接受治疗的67名精神分裂症患者。采用Jaroszyński抑郁和偏执评分对患者进行评价。几乎在所有病例中都发现了情感障碍,其中抑郁症状最为常见。抑郁症的发展或加重只能部分归因于抗精神病药物的作用。在偏执型和周期性精神分裂症的情感障碍的临床模式上没有发现差异。在偏执抑郁综合征中,复杂活动减少和精神抑制的治疗效果最好。具有某些胸腺功能的抗精神病药物被用于治疗这些病例,有时与三环抗抑郁药联合使用。结果显示,患者对现状表现出明显的焦虑、抑制和抑郁态度。此组患者在服用三环类抗抑郁药期间有时出现偏执性生产症状。
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引用次数: 0
Insulin secretion in patients with chronic hepatitis treated with lipostabil. 利泊他比治疗慢性肝炎患者胰岛素分泌的变化。
J Kuska, F Kokot

In 12 patients with chronic hepatitis the carbohydrate tolerance and insulin secretion after intravenous and oral glucose loading were determined before and after lipostabil treatment. A significant rise of fasting insulinemia and hypersecretion of insulin after intravenous glucose loading were observed. After oral glucose loading the rise of insulinemia was significantly lower in patients than in healthy controls, despite a greater increase in glycemia. Administration of lipostabil for 2 weeks failed to exert any significant effect on carbohydrate intolerance and disturbances in insulin secretion, which were present in patients with chronic hepatitis.

对12例慢性肝炎患者进行糖耐量和胰岛素分泌的测定。观察到静脉葡萄糖负荷后空腹胰岛素血症和胰岛素高分泌显著上升。口服葡萄糖负荷后,患者胰岛素血症的升高明显低于健康对照组,尽管血糖升高幅度较大。给药2周后,对慢性肝炎患者存在的碳水化合物不耐受和胰岛素分泌紊乱没有任何显著影响。
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引用次数: 0
Electron microscopic findings in rat hypophysis after adrenalectomy and administration of ACTH. I. Adenohypophysis. 肾上腺切除术和ACTH给药后大鼠垂体的电镜观察。腺垂体。
A Danielewicz-Kotowicz

Ultrastructural changes in the secretory lobe of rat hypophysis following bilateral adrenalectomy and a single subcutaneous administration of 1 i.u. of ACTH were studied. Both after adrenalectomy and ACTH administration, ultrastructural changes were found to appear exclusively in one type of secretory cells. After adrenalectomy, pictures were found in these cells indicative of increased synthesis of the secretory granulations. One hour after the administration of ACTH the ACTH-secreting cells showed features of decreased secretory activity.

研究了双侧肾上腺切除术和单次皮下注射1 iu促肾上腺皮质激素后大鼠垂体分泌叶的超微结构变化。在肾上腺切除术和ACTH治疗后,超微结构的改变只出现在一种分泌细胞中。肾上腺切除术后,在这些细胞中发现图像表明分泌颗粒的合成增加。给药1小时后,促肾上腺皮质激素分泌细胞表现出分泌活性降低的特点。
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引用次数: 0
Intellectual efficiency and symptoms of the schizophrenic process. 精神分裂过程的智力效率和症状。
J Ostaszewska, I Stanikowska

The purpose of this work was to determine the influence of psychosis on the intellectual efficiency in psychotic patients. The scores obtained by schizophrenics tested according to the Wechsler-Bellevue scale were correlated with psychopathological symptoms established during psychiatric examination. The group included 55 patients (18 women and 37 men). The results were subjected to statistical analysis. The following correlations were disclosed: 1) a correlation between the results of Wechsler scale scores and sex as well as the educational level, 2) a more pronounced correlation between the presence of psychotic productions and the results of the performance scale (in relation to verbal scale), 3) higher variability of scores in the verbal scale than in the performances scale, 4) lack of correlation between the age, the age of onset and the results.

本研究旨在探讨精神病对精神病患者智力效率的影响。精神分裂症患者的韦氏量表得分与精神病学检查中建立的精神病理症状相关。本组共55例患者(女性18例,男性37例)。结果进行了统计分析。以下相关性被揭示:1)韦氏量表得分结果与性别以及受教育程度之间存在相关性;2)精神产物的存在与表现量表的结果(相对于言语量表)之间存在更明显的相关性;3)言语量表得分比表现量表得分的变异性更大;4)年龄、发病年龄与结果之间缺乏相关性。
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引用次数: 0
Primary pulmonary hypertension--a study of disturbances in circulatory hemodynamics and ventilatory function of the lungs. 原发性肺动脉高压——循环血流动力学和肺通气功能紊乱的研究。
J P Dubiel, Z Pyzik

Investigations of the hemodynamics of pulmonary circulation, right and left heart venticle and ventilatory function of the lungs were carried out in a group of 12 patients with primary pulmonary hypertension. The results were discussed in the light of data obtained in a group of 16 patients with chronic cor pulmonale syndrome and 16 healthy subjects. It was found that patients with primary pulmonary hypertension show a markedly raised pressure in the pulmonary artery mean pressure x = 60.3 +/- 24.2 mm Hg, in the right ventricle (systolic pressure x = 90.6 +/- 27.9 mm Hg, end-diastolic pressure x = 11.7 +/- 4.3 mm Hg), very high total pulmonary vascular resistance (x = 1571 +/- dynes. sec. cm-5) and increased work of right ventricle (x = 2.3 +/- 1.5 kgm/min/m2). In patients with chronic cor pulmonale syndrome the load on the right ventricle was much lower. The indices determining left ventricle function as a pump indicated that this function was impaired, with lower cardiac index (x = 2.1 +/- 0.8 1/min/m2), stroke volume (x = 41.7 +/- 17.2 ml) and left ventricular work (x = 2.7 +/- 1.1 kgm/min/m2). These changes might, however, be due also to impaired blood flow into the left ventricle. In contrast to patients with chronic cor pulmonale syndrome, the indices of ventilatory function of the lungs were normal or only slightly decreased. No significant correlations were observed between hemodynamic indices of pulmonary circulation and right ventricle and the parameters of the ventilatory function of the lungs.

对12例原发性肺动脉高压患者进行了肺循环血流动力学、左、右心室及肺通气功能的观察。本文结合16例慢性肺心病患者和16例健康人的数据进行了讨论。发现原发性肺动脉高压患者肺动脉平均压明显升高x = 60.3 +/- 24.2 mm Hg,右心室(收缩压x = 90.6 +/- 27.9 mm Hg,舒张末期压x = 11.7 +/- 4.3 mm Hg),肺血管总阻力非常高(x = 1571 +/- dynes)。秒(cm-5)和右心室功增加(x = 2.3 +/- 1.5 kgm/min/m2)。慢性肺心病患者右心室负荷要低得多。测定左心室作为泵功能的指标表明,左心室功能受损,心脏指数(x = 2.1 +/- 0.8 1/min/m2)、搏容量(x = 41.7 +/- 17.2 ml)和左心室功(x = 2.7 +/- 1.1 kgm/min/m2)降低。然而,这些变化也可能是由于流入左心室的血流量受损。与慢性肺心病患者相比,肺通气功能指标正常或仅轻微下降。肺循环和右心室血流动力学指标与肺通气功能参数无显著相关性。
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Polish medical sciences and history bulletin
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