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Orthogonal polynomial trend analysis helps interpreting abnormalities in event-related brain potentials in high functioning autism 正交多项式趋势分析有助于解释高功能自闭症事件相关脑电位异常
J. Stauder, J. C. Woestenburg, F. Hassainia, L. Mottron, P. Robaey
Orthogonal polynomial trend analysis allows the extraction of event-related brain activity on basis of a few stimulus presentations enabling the study of time on task changes in event-related brain activity. The impact of this information on the interpretation of conventionally averaged event-related potentials is illustrated by comparing a high functioning autism group to matched controls.
正交多项式趋势分析可以在少量刺激呈现的基础上提取与事件相关的大脑活动,从而研究与事件相关的大脑活动的任务时间变化。通过将高功能自闭症组与匹配的对照组进行比较,可以说明这些信息对传统平均事件相关电位解释的影响。
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引用次数: 2
A real-time, interactive, 3-dimensional, computer graphic system for the study of one, two, and three degree-of-freedom joints in rotation 一种实时、交互式、三维的计算机图形系统,用于研究旋转中的一、二、三自由度关节
Horng-Haur Liu, W. Buford, R. Patterson
A system is described which provides for the arbitrary placement of axes of motion with respect to 3-D anatomical (skeletal) structures. The system extends upon earlier work in the interactive, real-time, simulation of musculoskeletal kinematics. Developed in a UNIX RISC platform, the simulation uses PHIGS Extension to X windows (PEX) to define kinematics models and Motif widgets for control of modeling variables through mouse, control dial, and keyboard interaction. Skeletal structures are triangular shaded polygons developed from Computerized Tomography (CT) scans. Rotational axes of motion represented by long, narrow cylindrical vectors are arbitrarily placed and fixed with respect to skeletal landmarks. Subsequent motion of distal bone segments are then controlled, visualized, and studied for verification of joint congruence and realistic placement. This report describes the simulation applied to the three joints of the thumb (up to six degrees of freedom), the wrist, and the knee (two degrees of freedom each).
描述了一种系统,该系统提供了相对于三维解剖(骨骼)结构的运动轴的任意放置。该系统扩展了早期在交互式、实时、肌肉骨骼运动学仿真方面的工作。该仿真在UNIX RISC平台上开发,使用PHIGS扩展到X窗口(PEX)来定义运动学模型和Motif小部件,通过鼠标、控制拨盘和键盘交互来控制建模变量。骨骼结构是由计算机断层扫描(CT)形成的三角形阴影多边形。运动的旋转轴由长而窄的圆柱形矢量表示,相对于骨骼地标被任意放置和固定。然后控制、可视化和研究远端骨段的后续运动,以验证关节一致性和真实的放置。本报告描述了应用于拇指(最多六个自由度)、手腕和膝盖(每个两个自由度)三个关节的模拟。
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引用次数: 0
A proposal of a model for the glomerular filtration 肾小球滤过模型的提出
L. Roa, F. Garrachon, T. Gómez-Cía
A model of glomerular filtration has been developed, which aims to be of clinical application, easier to use and compute, and powerful. A new approach has been considered, assuming actual knowledge on the flow and filtration components and regulation. Its physiological bases and quantifications are shown.
建立了一种具有临床应用价值、易于使用和计算、功能强大的肾小球滤过模型。考虑了一种新的方法,假设对流动和过滤组件和调节有实际的了解。并给出了其生理基础和定量分析。
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引用次数: 0
Load sharing among muscles and dynamic relationship between multi-muscle EMGs and isometric joint moment 肌肉间负荷分担及多肌肌电图与关节力矩的动态关系
Li-Qun Zhang, W. Rymer, G. Nuber
An in vivo and noninvasive technique was developed to determine the human elbow extension moment distribution among the 3 heads of the triceps and the anconeus muscles, and to model the relationship between the multi-muscle EMGs and the joint extension moment dynamically. The static M-wave and joint moment relationships for each head of the muscles was used to calibrate the EMG signals and determine load sharing during voluntary tasks. Results showed that the medial head triceps was the prime elbow extensor and the anconeus contributed significantly at low levels of the extension moment. Both load sharing and the model parameters varied with the joint extension moment. Contributions of the medial head triceps and anconeus decreased with the mean joint moment, while those of the lateral and long heads of triceps increased with it.
建立了一种体内无创技术,测定人体肘关节在肱三头肌和踝关节肌间的伸展力矩分布,动态模拟多肌肌电图与关节伸展力矩之间的关系。每个肌肉头部的静态m波和关节力矩关系被用来校准肌电图信号,并确定自愿任务期间的负荷分担。结果表明,内侧头三头肌是肘关节的主要伸肌,而在低水平的伸力矩时,肘关节的侧背肌起着重要的作用。荷载分担和模型参数均随节点伸展力矩的变化而变化。内侧头三头肌和踝关节的贡献随平均关节力矩的增大而减小,外侧头和长头三头肌的贡献随平均关节力矩的增大而增大。
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引用次数: 1
DefibSim: an interactive defibrillation device design tool defbsim:交互式除颤装置设计工具
J. A. Schmidt, C.R. Johnson
We have developed an interactive computer modeling tool (DefibSim) for defibrillation device design. This system allows researchers to interactively design and place electrodes within a large-scale thorax model and then compute the electric and potential fields using an adaptive finite element method. Both visual and quantitative measures have been developed to determine the efficacy of different electrode configurations. This tool has allowed us to quickly and efficiently investigate over 170 different electrode configurations. A promising subset of electrode locations are now being tested in animals as well as in clinical environments.
我们开发了一个交互式计算机建模工具(defbsim),用于除颤装置的设计。该系统允许研究人员交互设计并将电极放置在大型胸腔模型中,然后使用自适应有限元方法计算电场和势场。目测和定量测量都已被开发出来,以确定不同电极配置的功效。该工具使我们能够快速有效地研究170多种不同的电极配置。一个有希望的电极位置子集现在正在动物和临床环境中进行测试。
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引用次数: 16
Frequency-domain techniques for heart rate variability analysis 心率变异性分析的频域技术
Xiangguo Yan, Chongxun Zheng
Two frequency domain techniques, fast Fourier transform (FFT) and maximum entropy estimation (MEE) methods for analyzing Heart Rate Variability (HRV), are described. Analysis results showed that low frequency components (LF:0.04-0.15 Hz) reflecting sympathetic nervous activity occupy a dominant position on day time, high frequency components (HF:0.4-0.40 Hz) reflecting vagal nervous activity become stronger at night. There is a cluster of peaks ranging from 0.20-0.30 Hz at night. In the morning, LF/HF ratio trend graphics changed sharply. This may be quite significant for predicting sudden death of an intensive heart disease patient. Both analysis results have a high degree of positive correlation, and cross-correlation coefficient is more than 0.99. However, MEE has a higher frequency resolution than FFT.
描述了两种频域技术,快速傅里叶变换(FFT)和最大熵估计(MEE)方法,用于分析心率变异性(HRV)。分析结果表明,反映交感神经活动的低频分量(LF:0.04 ~ 0.15 Hz)在白天占主导地位,反映迷走神经活动的高频分量(HF:0.4 ~ 0.40 Hz)在夜间增强。夜间有一组波峰在0.20-0.30 Hz之间。早盘,低高频比趋势图形变化剧烈。这对于预测重症心脏病患者的猝死可能具有重要意义。两种分析结果均具有高度正相关,相关系数均大于0.99。然而,MEE具有比FFT更高的频率分辨率。
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引用次数: 3
Establishing predictive indicators of soft tissue status 建立软组织状态的预测指标
S.L. Gigg, D. Bader
This study investigates the effect of pressure and time on soft tissue status using measurements of transcutaneous gas tensions and the analysis of sweat metabolites of loaded sacral tissues. The tests were carried out on able-bodied subjects. Initial results show that there is an elevation in both lactate and urea in loaded tissues, which are associated with a decrease in oxygen tension are differences in the ratio of metabolites in loaded and unloaded tissue. The reperfusion of blood supply back into a loaded area of tissue was also apparent in the sweat analysis.
本研究通过测量经皮气体张力和分析负载的骶骨组织的汗液代谢物来研究压力和时间对软组织状态的影响。这些测试是在身体健全的受试者身上进行的。初步结果表明,负荷组织中乳酸和尿素的升高与氧张力的降低有关,这是负荷组织和未负荷组织中代谢物比例的差异。在汗液分析中,血液供应再灌注回组织负荷区域也很明显。
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引用次数: 1
Introduction of a new coronary stent with enhanced radioopacity and hemocompatibility 引入一种新型冠状动脉支架,增强放射线不透明和血液相容性
M. Amon, S. Winkler, K. Dekker, A. Bolz, C. Mittermayer, M. Schaldach
Despite procedural progress, stenting therapy is still limited by subacute thrombosis, late restenosis as well as anticoagulant related bleeding complications. These limitations are attributed to the insufficient hemocompatibility of the implants as well as their poor X-ray visibility which impedes the control of the devices during angiography. Therefore a new cardiovascular stent is proposed showing a high radioopacity as well as a high hemocompatibility. This was realized by a hybrid design, consisting of a tantalum substrate and an amorphous silicon carbide coating, allowing a separate optimization of the stent body and the coating.
尽管在手术上取得了进展,但支架治疗仍然受到亚急性血栓形成、晚期再狭窄以及抗凝相关出血并发症的限制。这些限制归因于植入物的血液相容性不足以及x射线能见度差,这阻碍了血管造影期间对设备的控制。因此,提出了一种具有高放射线不透光性和高血液相容性的新型心血管支架。这是通过混合设计实现的,由钽衬底和非晶碳化硅涂层组成,允许对支架主体和涂层进行单独优化。
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引用次数: 6
3D motion analysis of MR imaging using optical flow method 用光流法分析磁共振成像的三维运动
Siyi Huang, Shu-Tzu Wang, Jyh-Horng Chen
Optical flow is the velocity distribution of each pixel in an image. In this paper, the authors extend the 2D optical flow method to 3D optical flow analysis and also improve its performance around boundaries. Dynamic analysis of heart and knee is under investigation.
光流是图像中每个像素的速度分布。本文将二维光流分析方法推广到三维光流分析中,并改进了其在边界处的性能。心脏和膝盖的动态分析正在研究中。
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引用次数: 2
Optimal operating point controller for total artificial heart 全人工心脏最佳工作点控制器
M. Yoshizawa, A. Tanaka, K. Abe, H. Takeda, T. Yambe, S. Nitta, Y. Abe, K. Imachi
In order to make an air-driven total artificial heart (TAR) implantable, the optimal operating point control method has been applied to the TAH controller. Because this method needs only the outflow rate of blood to regulate the stroke volume, it is not necessary to visually monitor the state of the sac in the implanted blood pump. Animal experiments have been carried out to evaluate the proposed controller by using an adult goat walking on a treadmill.
为了使气动全人工心脏(TAR)具有可移植性,将最佳工作点控制法应用于全人工心脏控制器。由于这种方法只需要血液的流出率来调节搏量,因此不需要在植入血泵中目视监测囊的状态。动物实验通过一只成年山羊在跑步机上行走来评估所提出的控制器。
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引用次数: 0
期刊
Proceedings of 17th International Conference of the Engineering in Medicine and Biology Society
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