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PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON ADVANCED MATERIALS WITH HIERARCHICAL STRUCTURE FOR NEW TECHNOLOGIES AND RELIABLE STRUCTURES 2019最新文献

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The effect of a textured surface layer on the deformation behavior of polycrystalline titanium 织构表面层对多晶钛变形行为的影响
E. Emelianova, V. Romanova, E. Dymnich, M. Pisarev
The effect of a textured surface layer on the deformation behavior of surface-modified titanium is numerically investigated. A three-dimensional polycrystalline model accounting for the grain morphology was generated by a step-by-step packing method. A crystal plasticity-based constitutive model describing the anisotropic elastic-plastic behavior of individual grains is implemented in a dynamic boundary-value problem that is numerically solved using ABAQUS/Explicit finite element package. Two sets of calculations for polycrystalline models with textured and untextured surface layers were performed. Conclusions on the surface texture effect on the stress and strain fields and surface roughening in the surface and in the bulk of the polycrystals were drawn.The effect of a textured surface layer on the deformation behavior of surface-modified titanium is numerically investigated. A three-dimensional polycrystalline model accounting for the grain morphology was generated by a step-by-step packing method. A crystal plasticity-based constitutive model describing the anisotropic elastic-plastic behavior of individual grains is implemented in a dynamic boundary-value problem that is numerically solved using ABAQUS/Explicit finite element package. Two sets of calculations for polycrystalline models with textured and untextured surface layers were performed. Conclusions on the surface texture effect on the stress and strain fields and surface roughening in the surface and in the bulk of the polycrystals were drawn.
用数值方法研究了织构面层对表面改性钛的变形行为的影响。采用分步堆积的方法生成了考虑晶粒形貌的三维多晶模型。采用ABAQUS/Explicit有限元软件对动态边值问题进行数值求解,建立了基于晶体塑性的本构模型,描述了单个晶粒的各向异性弹塑性行为。对具有纹理表面层和非纹理表面层的多晶模型进行了两组计算。得出了表面织构对多晶表面和本体的应力场、应变场和表面粗糙度的影响。用数值方法研究了织构面层对表面改性钛的变形行为的影响。采用分步堆积的方法生成了考虑晶粒形貌的三维多晶模型。采用ABAQUS/Explicit有限元软件对动态边值问题进行数值求解,建立了基于晶体塑性的本构模型,描述了单个晶粒的各向异性弹塑性行为。对具有纹理表面层和非纹理表面层的多晶模型进行了两组计算。得出了表面织构对多晶表面和本体的应力场、应变场和表面粗糙度的影响。
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引用次数: 0
Characteristics of products of thermal conversion of oil shales in supercritical benzene 超临界苯作用下油页岩热转化产物特性研究
A. Petrov, E. Y. Kovalenko, T. Sagachenko, R. S. Min, Y. Patrakov
A complex of methods of investigation (elemental analysis, cryoscopy in benzene, IR and NMR spectroscopy) is used to characterize the liquid products of thermal degradation of combustible shale samples in benzene under supercritical conditions. The samples differ in the type of the original OM. It is found out that pyrolysates withdrawn in the temperature ranges up to 200, 200–300, 300–400, 400–480°C differ in their molecular mass, content of resin-asphaltene components and heteroatoms, and the H/C atomic ratio. It is shown that pyrolysates obtained from OM of the type II have higher average molecular masses, lower concentrations of heteroatoms, and contain more of oil components than pyrolysates obtained from OM of the type I. The results of the study are important for the choice of methods for processing combustible shale, purposing to obtain chemically useful components based on them.A complex of methods of investigation (elemental analysis, cryoscopy in benzene, IR and NMR spectroscopy) is used to characterize the liquid products of thermal degradation of combustible shale samples in benzene under supercritical conditions. The samples differ in the type of the original OM. It is found out that pyrolysates withdrawn in the temperature ranges up to 200, 200–300, 300–400, 400–480°C differ in their molecular mass, content of resin-asphaltene components and heteroatoms, and the H/C atomic ratio. It is shown that pyrolysates obtained from OM of the type II have higher average molecular masses, lower concentrations of heteroatoms, and contain more of oil components than pyrolysates obtained from OM of the type I. The results of the study are important for the choice of methods for processing combustible shale, purposing to obtain chemically useful components based on them.
采用复杂的研究方法(元素分析、苯低温、红外和核磁共振光谱)来表征超临界条件下可燃页岩样品在苯中热降解的液体产物。样品和原OM的型号不一样。结果表明,在200、200 - 300、300-400、400-480℃范围内提取的热解产物在分子质量、树脂-沥青质组分和杂原子含量、H/C原子比等方面存在差异。结果表明,ⅱ型有机质热解产物比ⅰ型有机质热解产物具有更高的平均分子质量,更低的杂原子浓度,含有更多的油组分。研究结果对选择处理可燃页岩的方法,以获得化学上有用的组分具有重要意义。采用复杂的研究方法(元素分析、苯低温、红外和核磁共振光谱)来表征超临界条件下可燃页岩样品在苯中热降解的液体产物。样品和原OM的型号不一样。结果表明,在200、200 - 300、300-400、400-480℃范围内提取的热解产物在分子质量、树脂-沥青质组分和杂原子含量、H/C原子比等方面存在差异。结果表明,ⅱ型有机质热解产物比ⅰ型有机质热解产物具有更高的平均分子质量,更低的杂原子浓度,含有更多的油组分。研究结果对选择处理可燃页岩的方法,以获得化学上有用的组分具有重要意义。
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引用次数: 1
Deformation as a measure of conformality deviation 变形,作为一致性偏差的量度
V. Kibitkin
The plane vector field for solid with constant deformation is considered. The formulae for components of the field are given. Linear character of a displacement fields and its evolution is shown at the example of plastic flow of base metal of welded joint in the neck region. Two consequent vector fields give the summary field as their sum. The high-cyclic fatigue of welded joints of Fe-17Cr-0.8Ti-0.08C steel was used to analyze. The criteria of deviation the vector field from the field, which components can be described by analytical functions, are considered. It is shown that summary declination of these criteria from the Cauchy–Riemann equations is closed to deformation. Therefore, only non-linear components of the deformation can satisfied to Cauchy–Riemann equations for the next conformal transformation.The plane vector field for solid with constant deformation is considered. The formulae for components of the field are given. Linear character of a displacement fields and its evolution is shown at the example of plastic flow of base metal of welded joint in the neck region. Two consequent vector fields give the summary field as their sum. The high-cyclic fatigue of welded joints of Fe-17Cr-0.8Ti-0.08C steel was used to analyze. The criteria of deviation the vector field from the field, which components can be described by analytical functions, are considered. It is shown that summary declination of these criteria from the Cauchy–Riemann equations is closed to deformation. Therefore, only non-linear components of the deformation can satisfied to Cauchy–Riemann equations for the next conformal transformation.
考虑恒定变形固体的平面矢量场。给出了场分量的计算公式。以焊接接头颈部母材塑性流动为例,说明了位移场的线性特征及其演化规律。两个后向向量场给出总结场作为它们的和。采用Fe-17Cr-0.8Ti-0.08C钢焊接接头进行了高周疲劳分析。考虑了向量场与场的偏离准则,其中的分量可以用解析函数来描述。从Cauchy-Riemann方程得出的这些判据的总偏角与变形密切相关。因此,只有变形的非线性分量才能满足下一个保形变换的Cauchy-Riemann方程。考虑恒定变形固体的平面矢量场。给出了场分量的计算公式。以焊接接头颈部母材塑性流动为例,说明了位移场的线性特征及其演化规律。两个后向向量场给出总结场作为它们的和。采用Fe-17Cr-0.8Ti-0.08C钢焊接接头进行了高周疲劳分析。考虑了向量场与场的偏离准则,其中的分量可以用解析函数来描述。从Cauchy-Riemann方程得出的这些判据的总偏角与变形密切相关。因此,只有变形的非线性分量才能满足下一个保形变换的Cauchy-Riemann方程。
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引用次数: 0
Effect of binder composition on properties of 316L stainless steel bimodal powder feedstock 粘结剂组成对316L不锈钢双峰粉料性能的影响
N. Toropkov, E. Glazkova, N. Rodkevich, A. Pervikov, M. Lerner
Metal powder composites for powder injection molding (PIM) technology have been studied. Stainless steel 316L bimodal powders consisting of both nano and microparticles and multicomponent binders based on PLA/PMMA (feedstock I), paraffin wax/PE-LD/PMMA (feedstock II) and polyethylene wax (feedstock III) were used to obtain feedstock. The effect of the binder composition on the characteristics of feedstocks and sintered compacts was investigated. The use of PMMA in a binder allows maintaining the strength of the compacts to high temperatures when sintering. The debinding of “green compacts” from feedstock III leads to an almost complete removal of paraffin wax, and the “brown” parts retain their shape only due to the low-temperature sintering of nanoparticles. The use of the paraffin wax as a binder requires an increase in the content of the bimodal metal powder in the feedstock to 95 wt% to increase the strength of the compacts. Feedstocks and molded compacts were characterized by TEM, SEM, DSC-TG methods.Metal powder composites for powder injection molding (PIM) technology have been studied. Stainless steel 316L bimodal powders consisting of both nano and microparticles and multicomponent binders based on PLA/PMMA (feedstock I), paraffin wax/PE-LD/PMMA (feedstock II) and polyethylene wax (feedstock III) were used to obtain feedstock. The effect of the binder composition on the characteristics of feedstocks and sintered compacts was investigated. The use of PMMA in a binder allows maintaining the strength of the compacts to high temperatures when sintering. The debinding of “green compacts” from feedstock III leads to an almost complete removal of paraffin wax, and the “brown” parts retain their shape only due to the low-temperature sintering of nanoparticles. The use of the paraffin wax as a binder requires an increase in the content of the bimodal metal powder in the feedstock to 95 wt% to increase the strength of the compacts. Feedstocks and molded compacts were characterized by TEM, SEM, DSC-TG methods.
研究了用于粉末注射成型(PIM)技术的金属粉末复合材料。采用基于PLA/PMMA(原料I)、石蜡/PE-LD/PMMA(原料II)和聚乙烯蜡(原料III)的多组分粘结剂和纳米和微粒组成的不锈钢316L双峰粉末获得原料。研究了粘结剂的组成对原料性能和烧结坯性能的影响。在粘合剂中使用PMMA可以在烧结时保持致密物在高温下的强度。原料III的“绿色致密物”的脱粘导致石蜡几乎完全去除,而“棕色”部分仅由于纳米颗粒的低温烧结而保持其形状。使用石蜡作为粘结剂需要将原料中双峰金属粉末的含量增加到95%,以提高压坯的强度。采用TEM、SEM、DSC-TG等方法对原料和成型坯进行了表征。研究了用于粉末注射成型(PIM)技术的金属粉末复合材料。采用基于PLA/PMMA(原料I)、石蜡/PE-LD/PMMA(原料II)和聚乙烯蜡(原料III)的多组分粘结剂和纳米和微粒组成的不锈钢316L双峰粉末获得原料。研究了粘结剂的组成对原料性能和烧结坯性能的影响。在粘合剂中使用PMMA可以在烧结时保持致密物在高温下的强度。原料III的“绿色致密物”的脱粘导致石蜡几乎完全去除,而“棕色”部分仅由于纳米颗粒的低温烧结而保持其形状。使用石蜡作为粘结剂需要将原料中双峰金属粉末的含量增加到95%,以提高压坯的强度。采用TEM、SEM、DSC-TG等方法对原料和成型坯进行了表征。
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引用次数: 1
The effect of solid-solution temperature on phase composition and tensile properties of vanadium-alloyed high interstitial steels 固溶温度对钒合金高间隙钢相组成及拉伸性能的影响
S. Astafurov, G. Maier, I. Tumbusova, E. Melnikov, V. Moskvina, M. Panchenko, N. Galchenko, E. Astafurova
Using different solid solution treatments, two structural states were produced in high-interstitial austenitic Fe-19Cr-22Mn-1.6V-0.4C-0.8N and Fe-22Cr-26Mn-1.3V-0.7C-1.2N (all in wt %) steels. Room...
采用不同的固溶处理,高间隙奥氏体钢Fe-19Cr-22Mn-1.6V-0.4C-0.8N和Fe-22Cr-26Mn-1.3V-0.7C-1.2N(均以wt %计)产生了两种组织状态。房间……
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引用次数: 0
Complex investigation of the mechanical properties and structural-phase composition of high-strength laser welding connections of the aluminum alloy 1420 1420铝合金高强度激光焊接接头力学性能和组织相组成的复杂研究
A. Malikov, A. Orishich, E. Karpov, I. Vitoshkin
The paper presents a series of experimental works for the optimization of the thermal post-treatment process (quenching and artificial ageing) of the laser welding joints of aluminum-lithium alloy 1420 (the system Al-Mg-Li) by the temperature and time characteristics, in order to find the breaking stress, yield limit and ultimate tensile strain approaching to the respective characteristics of the main alloy, or equal to them. Low-cycle tests have been done with the thermally-treated welding joints for the pulsing stretching at various loading amplitudes at the temperatures of –60, +20, +85°С. The surface structure of ruptured welding joints with and without thermal treatment has been studied after low cycle tests at various loading amplitudes at the increased and decreased temperatures.
本文通过对1420铝锂合金(Al-Mg-Li体系)激光焊接接头的温度和时间特性进行了一系列的实验研究,优化了热后处理工艺(淬火和人工时效),使其断裂应力、屈服极限和极限拉伸应变接近或等于主合金各自的特性。对热处理焊接接头在-60、+20、+85°С温度下不同加载幅度下的脉冲拉伸进行了低周试验。通过低周试验,研究了在不同加载幅值和不同温度下,经过热处理和不经过热处理的断裂焊接接头的表面组织。
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引用次数: 0
The influence of oxygen and fluorine on the electronic structure of InAlAs surface 氧和氟对InAlAs表面电子结构的影响
A. Bakulin, A. Fuks, M. Aksenov, N. A. Valisheva, S. Kulkova
The projector augmented-wave method is applied for investigation of oxygen and fluorine adsorption on the cation-terminated InAlAs(111) unreconstructed surface. The binding energies of both adsorbates with semiconductor surface are estimated. Their influence on the surface band structure and states within band gap is analyzed. It is shown that oxygen adsorption leads to appearance of additional surface states in the fundamental gap, whereas fluorine coadsorption results in partial or complete removal of the surface state and an unpinning of the Fermi level.The projector augmented-wave method is applied for investigation of oxygen and fluorine adsorption on the cation-terminated InAlAs(111) unreconstructed surface. The binding energies of both adsorbates with semiconductor surface are estimated. Their influence on the surface band structure and states within band gap is analyzed. It is shown that oxygen adsorption leads to appearance of additional surface states in the fundamental gap, whereas fluorine coadsorption results in partial or complete removal of the surface state and an unpinning of the Fermi level.
应用投影增强波法研究了氧和氟在阳离子端InAlAs(111)未重构表面的吸附。估计了两种吸附剂与半导体表面的结合能。分析了它们对带隙内表面能带结构和状态的影响。结果表明,氧吸附导致在基本间隙中出现额外的表面态,而氟共吸附导致部分或完全去除表面态并解除费米能级。应用投影增强波法研究了氧和氟在阳离子端InAlAs(111)未重构表面的吸附。估计了两种吸附剂与半导体表面的结合能。分析了它们对带隙内表面能带结构和状态的影响。结果表明,氧吸附导致在基本间隙中出现额外的表面态,而氟共吸附导致部分或完全去除表面态并解除费米能级。
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引用次数: 0
Effect of the strain rate on the low cycle fatigue behavior of a 10Cr-2W-Mo-3Co-NbV steel at room temperature 应变速率对10Cr-2W-Mo-3Co-NbV钢室温低周疲劳行为的影响
R. Mishnev, N. Dudova, R. Kaibyshev
The effect of a strain rate varying from ∼10−3 to ∼10−5 s−1 at a strain amplitude ranging from ±0.25% to ±0.6% on the low cycle fatigue (LCF) behavior and the microstructure of a 10%Cr-2%W-0.7%Mo-3%Co-NbV steel with 0.008 wt.% B and 0.003 wt.% N additions was studied at room temperature. The number of cycles to failure tends to slightly increase with decreasing the strain rate. The fatigue lifetime curves at all tested strain rates and strain amplitudes could be described using the Basquin-Manson-Coffin relationship. The transition life of 2Nt, when plastic and elastic strain components are equal, shifted to higher reversals with a decrease in the strain rate from ∼10−3 to ∼10−4 and ∼10−5 s−1, whereas the transition total strain amplitude, when plastic and elastic strain components are equal, remained unchanged. It was found that despite the weak influence of strain rate on the lifetime and microhardness, a decrease in the strain rate facilitates the knitting reaction.The effect of a strain rate varying from ∼10−3 to ∼10−5 s−1 at a strain amplitude ranging from ±0.25% to ±0.6% on the low cycle fatigue (LCF) behavior and the microstructure of a 10%Cr-2%W-0.7%Mo-3%Co-NbV steel with 0.008 wt.% B and 0.003 wt.% N additions was studied at room temperature. The number of cycles to failure tends to slightly increase with decreasing the strain rate. The fatigue lifetime curves at all tested strain rates and strain amplitudes could be described using the Basquin-Manson-Coffin relationship. The transition life of 2Nt, when plastic and elastic strain components are equal, shifted to higher reversals with a decrease in the strain rate from ∼10−3 to ∼10−4 and ∼10−5 s−1, whereas the transition total strain amplitude, when plastic and elastic strain components are equal, remained unchanged. It was found that despite the weak influence of strain rate on the lifetime and microhardness, a decrease in the strain rate facilitates the knitting reaction.
在室温下,研究了应变速率为~ 10−3 ~ ~ 10−5 s−1,应变幅度为±0.25% ~±0.6%时,对添加0.008 wt.% B和0.003 wt.% N的10%Cr-2%W-0.7%Mo-3%Co-NbV钢的低周疲劳行为和显微组织的影响。随着应变速率的减小,失效循环次数有轻微增加的趋势。在所有测试应变速率和应变幅值下的疲劳寿命曲线都可以用Basquin-Manson-Coffin关系来描述。当塑性应变分量和弹性应变分量相等时,随着应变速率从~ 10−3到~ 10−4和~ 10−5 s−1的减小,2Nt的过渡寿命向更高的反转方向移动,而当塑性应变分量和弹性应变分量相等时,过渡总应变幅保持不变。结果表明,应变速率对寿命和显微硬度的影响较小,但应变速率的降低有利于针织反应的发生。在室温下,研究了应变速率为~ 10−3 ~ ~ 10−5 s−1,应变幅度为±0.25% ~±0.6%时,对添加0.008 wt.% B和0.003 wt.% N的10%Cr-2%W-0.7%Mo-3%Co-NbV钢的低周疲劳行为和显微组织的影响。随着应变速率的减小,失效循环次数有轻微增加的趋势。在所有测试应变速率和应变幅值下的疲劳寿命曲线都可以用Basquin-Manson-Coffin关系来描述。当塑性应变分量和弹性应变分量相等时,随着应变速率从~ 10−3到~ 10−4和~ 10−5 s−1的减小,2Nt的过渡寿命向更高的反转方向移动,而当塑性应变分量和弹性应变分量相等时,过渡总应变幅保持不变。结果表明,应变速率对寿命和显微硬度的影响较小,但应变速率的降低有利于针织反应的发生。
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引用次数: 0
Finite deformation analysis of a prestressed elastic beam after the layer addition 预应力弹性梁加层后的有限变形分析
V. Levin, K. Zingerman, A. Vershinin, D. Konovalov
An approach to the numerical modeling of stress state in a two-layered beam is developed for finite deformations. It is assumed that the first layer of the beam is preliminarily stressed, and then the second layer is added. The problem is formulated and solved using the theory of repeatedly superimposed finite strains. The spectral element method is used for the analysis. The spectral elements of variable order are used on non-conformal unstructured meshes. The computations are performed for the case of plane strain. It is assumed that the beam is made of the weakly compressible Mooney-Rivlin material. The incomplete junction of layers is considered. The numerical results are given for the case in which the first layer is preliminarily stretched along its axis. It is analyzed how the curvature of the beam after the junction of layers depends on the value of preliminary stretch. It is shown that this dependence is not monotone. The stress distribution in the composite beam is shown for a particular case. The proposed approach can be useful for the modeling of additive manufacturing. In this case the preliminary strains and stresses in the first layer are caused by thermal effects.An approach to the numerical modeling of stress state in a two-layered beam is developed for finite deformations. It is assumed that the first layer of the beam is preliminarily stressed, and then the second layer is added. The problem is formulated and solved using the theory of repeatedly superimposed finite strains. The spectral element method is used for the analysis. The spectral elements of variable order are used on non-conformal unstructured meshes. The computations are performed for the case of plane strain. It is assumed that the beam is made of the weakly compressible Mooney-Rivlin material. The incomplete junction of layers is considered. The numerical results are given for the case in which the first layer is preliminarily stretched along its axis. It is analyzed how the curvature of the beam after the junction of layers depends on the value of preliminary stretch. It is shown that this dependence is not monotone. The stress distribution in the composite beam is shown for a particular case. T...
提出了一种两层梁有限变形应力状态的数值模拟方法。假设对梁的第一层进行初步受力,然后再加第二层。该问题是用有限应变重复叠加理论来表述和求解的。采用谱元法进行分析。变阶谱元用于非保形非结构网格。对平面应变情况进行了计算。假定光束是由弱可压缩的Mooney-Rivlin材料构成的。考虑了层间的不完全连接。给出了沿轴向初步拉伸第一层的数值结果。分析了层结后梁的曲率与初拉伸值的关系。结果表明,这种依赖关系不是单调的。给出了一种特殊情况下复合梁的应力分布。该方法可用于增材制造的建模。在这种情况下,第一层的初步应变和应力是由热效应引起的。提出了一种两层梁有限变形应力状态的数值模拟方法。假设对梁的第一层进行初步受力,然后再加第二层。该问题是用有限应变重复叠加理论来表述和求解的。采用谱元法进行分析。变阶谱元用于非保形非结构网格。对平面应变情况进行了计算。假定光束是由弱可压缩的Mooney-Rivlin材料构成的。考虑了层间的不完全连接。给出了沿轴向初步拉伸第一层的数值结果。分析了层结后梁的曲率与初拉伸值的关系。结果表明,这种依赖关系不是单调的。给出了一种特殊情况下复合梁的应力分布。T…
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引用次数: 1
Development of a polymeric scaffold for vascular tissue engineering 血管组织工程用高分子支架的研制
E. Velikanova, V. Matveeva, E. Krivkina, V. Sevostianova, M. Khanova, T. V. Glushkova, Y. Kudryavtseva, L. Antonova
An important area of tissue engineering is the development of small-dimeter vascular grafts. In our study we assessed whether an electrospun polymer scaffold is beneficial for developing a tissue-engineered graft. The polymeric grafts were made from a blend of polyhydroxybutyrate/valerate and polycaprolactone (PHBV/PCL) and added type I collagen. Additionally, the grafts were treated with fibronectin. Cells were isolated from the peripheral blood of patients with coronary artery disease (CAD) and then seeded on the luminal graft surface. Then, the grafts with cells were cultured in a pulsatile flow bioreactor. We confirmed that separate feeding of PHBV/PCL and type I collagen during electrospinning allows developing a scaffold for a vascular graft suitable for maintaining the viability of the endothelial layer on the luminal surface.An important area of tissue engineering is the development of small-dimeter vascular grafts. In our study we assessed whether an electrospun polymer scaffold is beneficial for developing a tissue-engineered graft. The polymeric grafts were made from a blend of polyhydroxybutyrate/valerate and polycaprolactone (PHBV/PCL) and added type I collagen. Additionally, the grafts were treated with fibronectin. Cells were isolated from the peripheral blood of patients with coronary artery disease (CAD) and then seeded on the luminal graft surface. Then, the grafts with cells were cultured in a pulsatile flow bioreactor. We confirmed that separate feeding of PHBV/PCL and type I collagen during electrospinning allows developing a scaffold for a vascular graft suitable for maintaining the viability of the endothelial layer on the luminal surface.
组织工程的一个重要领域是开发小直径血管移植物。在我们的研究中,我们评估了电纺丝聚合物支架是否有利于组织工程移植的发展。聚合物移植物由聚羟基丁酸酯/戊酸酯和聚己内酯(PHBV/PCL)的混合物和加入I型胶原制成。此外,用纤维连接蛋白处理移植物。从冠状动脉疾病(CAD)患者的外周血中分离细胞,然后将其植入移植物腔面。然后,在脉动流生物反应器中培养带细胞的移植物。我们证实,在静电纺丝过程中,PHBV/PCL和I型胶原蛋白的分离喂养可以为血管移植物提供适合维持管腔表面内皮层活力的支架。组织工程的一个重要领域是开发小直径血管移植物。在我们的研究中,我们评估了电纺丝聚合物支架是否有利于组织工程移植的发展。聚合物移植物由聚羟基丁酸酯/戊酸酯和聚己内酯(PHBV/PCL)的混合物和加入I型胶原制成。此外,用纤维连接蛋白处理移植物。从冠状动脉疾病(CAD)患者的外周血中分离细胞,然后将其植入移植物腔面。然后,在脉动流生物反应器中培养带细胞的移植物。我们证实,在静电纺丝过程中,PHBV/PCL和I型胶原蛋白的分离喂养可以为血管移植物提供适合维持管腔表面内皮层活力的支架。
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引用次数: 0
期刊
PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON ADVANCED MATERIALS WITH HIERARCHICAL STRUCTURE FOR NEW TECHNOLOGIES AND RELIABLE STRUCTURES 2019
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