Pub Date : 2012-11-23DOI: 10.3724/SP.J.1206.2011.00436
Xiaowei Guo, Pang Chen, Li Xiayu, L. Xiaoling, Liu Guiyuan
{"title":"The Structure and Function of SPLUNC1：Novel Class of Innate Immune Protective Molecules*: The Structure and Function of SPLUNC1：Novel Class of Innate Immune Protective Molecules*","authors":"Xiaowei Guo, Pang Chen, Li Xiayu, L. Xiaoling, Liu Guiyuan","doi":"10.3724/SP.J.1206.2011.00436","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00436","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"6 1","pages":"945-951"},"PeriodicalIF":0.3,"publicationDate":"2012-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84250489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-11-23DOI: 10.3724/SP.J.1206.2012.00027
Song Yang, Yan Teng, P. Xu
Dual-color two-photon laser scanning microscopy is a useful method for simultaneously studying the expression, localization and trafficking of two different proteins in tissues. Because most two-photon microscopes only use a single wavelength excitation laser, simultaneously exciting multiple fluorescent proteins remains a challenge. Here, we present mAmetrine and mKate2, which can be used as a novel fluorescent protein pair in dual-color two-photon imaging by taking advantage of the large Stokes shift of mAmetrine and high brightness of mKate2. Both proteins have high two-photon absorption efficiencies and can be simultaneously excited at an optical wavelength of 765 nm. Dual-color two-photon imaging using this protein pair is highly effective in living cells.
{"title":"A Novel Fluorescent Protein Pair for Dual-color Two-photon Laser Scanning Microscopy*: A Novel Fluorescent Protein Pair for Dual-color Two-photon Laser Scanning Microscopy*","authors":"Song Yang, Yan Teng, P. Xu","doi":"10.3724/SP.J.1206.2012.00027","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2012.00027","url":null,"abstract":"Dual-color two-photon laser scanning microscopy is a useful method for simultaneously studying the expression, localization and trafficking of two different proteins in tissues. Because most two-photon microscopes only use a single wavelength excitation laser, simultaneously exciting multiple fluorescent proteins remains a challenge. Here, we present mAmetrine and mKate2, which can be used as a novel fluorescent protein pair in dual-color two-photon imaging by taking advantage of the large Stokes shift of mAmetrine and high brightness of mKate2. Both proteins have high two-photon absorption efficiencies and can be simultaneously excited at an optical wavelength of 765 nm. Dual-color two-photon imaging using this protein pair is highly effective in living cells.","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"29 1","pages":"1012-1016"},"PeriodicalIF":0.3,"publicationDate":"2012-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73367716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-11-23DOI: 10.3724/SP.J.1206.2011.00617
Yongqi Pang, Gao-qi Wang, Xucheng Wang, Jia Chen, Xuecheng Wang
{"title":"A Brief Analysis of Subcellular Distribution and Physiological Functions of Plant Aquaporins*: A Brief Analysis of Subcellular Distribution and Physiological Functions of Plant Aquaporins*","authors":"Yongqi Pang, Gao-qi Wang, Xucheng Wang, Jia Chen, Xuecheng Wang","doi":"10.3724/SP.J.1206.2011.00617","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00617","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"16 1","pages":"962-971"},"PeriodicalIF":0.3,"publicationDate":"2012-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81985927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-11-15DOI: 10.3724/SP.J.1206.2012.00041
Qiang Li, Q. Han, Donghang Yu, Liu-Jun Tang, Jian Wang, Xiao-hui Wang, Wang-xiang Xu, Y. Zhan, Li Chang-Yan, Changhui Ge, Miao Yu, Xiao-Ming Yang
{"title":"JNK3 Cooperates With RelA/p65 to Decrease Bel-7402 Cell Adhesion Upon The Inhibition of NF-κB Pathway*: JNK3 Cooperates With RelA/p65 to Decrease Bel-7402 Cell Adhesion Upon The Inhibition of NF-κB Pathway*","authors":"Qiang Li, Q. Han, Donghang Yu, Liu-Jun Tang, Jian Wang, Xiao-hui Wang, Wang-xiang Xu, Y. Zhan, Li Chang-Yan, Changhui Ge, Miao Yu, Xiao-Ming Yang","doi":"10.3724/SP.J.1206.2012.00041","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2012.00041","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"113 1","pages":"877-886"},"PeriodicalIF":0.3,"publicationDate":"2012-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78420845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-11-15DOI: 10.3724/SP.J.1206.2012.00012
Bo Xiang, Wen Wang, Wen-juan Li, Ke Tang, Zhaoyang Zeng, L. Xiaoling, Liu Guiyuan
{"title":"NOR1 Regulates Morphogenetic Cell Behavior in vitro Coincident With Inhibition of a Non-canonical Wnt-signaling Cascade*: NOR1 Regulates Morphogenetic Cell Behavior in vitro Coincident With Inhibition of a Non-canonical Wnt-signaling Cascade*","authors":"Bo Xiang, Wen Wang, Wen-juan Li, Ke Tang, Zhaoyang Zeng, L. Xiaoling, Liu Guiyuan","doi":"10.3724/SP.J.1206.2012.00012","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2012.00012","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"44 1","pages":"887-892"},"PeriodicalIF":0.3,"publicationDate":"2012-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74492098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-11-15DOI: 10.3724/SP.J.1206.2011.00522
Wang Yijin, Wen Sheng-yun, Gong Haiyun, Gong Zhefeng, 龚哲峰, Liu Li, 刘力
Understanding the connection between sensory input and motor output is challenging.There is a need for good model systems to evaluate the molecular and neural mechanism of animal behavior.Here we show a new system for analyzing preference and plasticity of Drosophila egg-laying behavior.We found that selection of egg-laying site in flies is a good model to investigate the food preference in Drosophila.On sugar food with lower concentration,flies showed significant preference that was reduced upon the inhibition of olfactory pathway.Moreover,to examine the plasticity of egg-laying behavior,a new learning paradigm was devised.We associated light-dark cycle of egg-laying with different food conditions and found that flies could maintain egg-laying memory at least 3 days after training.This egg-laying system provides the basis for further study of molecular and neural mechanism underlying the relationship between environment and behavior.
{"title":"A Model System for Analyzing Behavioral Preference and Plasticity in Drosophila Egg-Laying","authors":"Wang Yijin, Wen Sheng-yun, Gong Haiyun, Gong Zhefeng, 龚哲峰, Liu Li, 刘力","doi":"10.3724/SP.J.1206.2011.00522","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00522","url":null,"abstract":"Understanding the connection between sensory input and motor output is challenging.There is a need for good model systems to evaluate the molecular and neural mechanism of animal behavior.Here we show a new system for analyzing preference and plasticity of Drosophila egg-laying behavior.We found that selection of egg-laying site in flies is a good model to investigate the food preference in Drosophila.On sugar food with lower concentration,flies showed significant preference that was reduced upon the inhibition of olfactory pathway.Moreover,to examine the plasticity of egg-laying behavior,a new learning paradigm was devised.We associated light-dark cycle of egg-laying with different food conditions and found that flies could maintain egg-laying memory at least 3 days after training.This egg-laying system provides the basis for further study of molecular and neural mechanism underlying the relationship between environment and behavior.","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"2 1","pages":"910-918"},"PeriodicalIF":0.3,"publicationDate":"2012-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85724338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-11-15DOI: 10.3724/SP.J.1206.2011.00513
Xihui Shen, Yonglin Hu, Dacheng Wang
{"title":"A Novel Substitution of The Heme-binding Residue Histidine-245 by Histidine-249 in Heme Oxygenase HugZ*: A Novel Substitution of The Heme-binding Residue Histidine-245 by Histidine-249 in Heme Oxygenase HugZ*","authors":"Xihui Shen, Yonglin Hu, Dacheng Wang","doi":"10.3724/SP.J.1206.2011.00513","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00513","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"24 2 1","pages":"871-876"},"PeriodicalIF":0.3,"publicationDate":"2012-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88672865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-11-15DOI: 10.3724/SP.J.1206.2011.00567
Jinjun He, Chuanjun Liu, Danhui Liu, Ji-fu Liu, Shanshan Wu, Xue-yuan Xiao, D. He
{"title":"PROL4 Elevates The Sensitivity of Lung Cancer Cell LTEP-a-2 to Cisplatin Treatment*: PROL4 Elevates The Sensitivity of Lung Cancer Cell LTEP-a-2 to Cisplatin Treatment*","authors":"Jinjun He, Chuanjun Liu, Danhui Liu, Ji-fu Liu, Shanshan Wu, Xue-yuan Xiao, D. He","doi":"10.3724/SP.J.1206.2011.00567","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00567","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"81 5 1","pages":"919-925"},"PeriodicalIF":0.3,"publicationDate":"2012-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83533311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-11-01DOI: 10.3724/SP.J.1206.2011.00442
Liang Kai-yun, Fu Qiufang, Fu Xiaolan
In probabilistic category learning tasks, people learn incrementally the "probabilistic" association between cues and outcomes. Here, we first discussed cognitive strategies used in probabilistic category learning, the unconsciousness of probabilistic category learning, as well as the relationship between probabilistic category learning and working memory and attention. Then, we reviewed the different roles of various brain regions, including the basal ganglia, the medial temporal lobe, the prefrontal lobe and the parietal lobe, in probabilistic category learning. Finally, we suggest that probabilistic category learning might involve both implicit and explicit processes and future research is needed to further explore the cognitive and neural mechanisms of probabilistic category learning.
{"title":"Cognitive and Neural Mechanisms of Probabilistic Category Learning*: Cognitive and Neural Mechanisms of Probabilistic Category Learning*","authors":"Liang Kai-yun, Fu Qiufang, Fu Xiaolan","doi":"10.3724/SP.J.1206.2011.00442","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00442","url":null,"abstract":"In probabilistic category learning tasks, people learn incrementally the \"probabilistic\" association between cues and outcomes. Here, we first discussed cognitive strategies used in probabilistic category learning, the unconsciousness of probabilistic category learning, as well as the relationship between probabilistic category learning and working memory and attention. Then, we reviewed the different roles of various brain regions, including the basal ganglia, the medial temporal lobe, the prefrontal lobe and the parietal lobe, in probabilistic category learning. Finally, we suggest that probabilistic category learning might involve both implicit and explicit processes and future research is needed to further explore the cognitive and neural mechanisms of probabilistic category learning.","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"91 1","pages":"1037-1044"},"PeriodicalIF":0.3,"publicationDate":"2012-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81583139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-10-09DOI: 10.3724/SP.J.1206.2011.00252
Hui Liu, Ziheng Zhuang, J. Guan, Shuigeng Zhou
{"title":"Transcriptional Regulation Functions of Nucleosome Positioning: a Survey*: Transcriptional Regulation Functions of Nucleosome Positioning: a Survey*","authors":"Hui Liu, Ziheng Zhuang, J. Guan, Shuigeng Zhou","doi":"10.3724/SP.J.1206.2011.00252","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00252","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"29 1","pages":"843-852"},"PeriodicalIF":0.3,"publicationDate":"2012-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90521160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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