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The Clinical Meaning of Withdrawal with Antidepressant Drugs. 抗抑郁药物戒断的临床意义。
IF 16.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-01-01 Epub Date: 2024-07-18 DOI: 10.1159/000540033
Giovanni A Fava
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引用次数: 0
Psychological Treatment of Comorbid Insomnia and Depression: A Double-Blind Randomized Placebo-Controlled Trial. 失眠与抑郁并发症的心理治疗:双盲随机安慰剂对照试验》。
IF 22.8 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-01-01 Epub Date: 2024-01-29 DOI: 10.1159/000536063
Kerstin Blom, Erik Forsell, Monica Hellberg, Cecilia Svanborg, Susanna Jernelöv, Viktor Kaldo

Introduction: Insomnia and depression are highly prevalent disorders and commonly occur together. Cognitive behavioral therapy for insomnia, CBT-I, has been shown to be effective in treating insomnia and also comorbid depression. However, it is unclear whether effects of CBT-I on depression are specific or nonspecific. Also, depressive symptoms often remain too high after CBT-I, indicating a need for improved treatments. The objective was to determine whether combining CBT-I with CBT for depression, without increasing treatment length, reduces both insomnia and depression more than CBT for depression with a placebo insomnia intervention.

Methods: A 12-week double-blind randomized controlled trial with a 6-month follow-up in a psychiatric setting using therapist-guided internet-delivered treatments was conducted. Patients (N = 126) were diagnosed with insomnia disorder and major depression by physicians. Primary outcome measures were as follows: self-rating scales Insomnia Severity Index (ISI) and Montgomery-Åsberg Depression Rating Scale (MADRS-S).

Results: The combined treatment showed specific effects on insomnia severity over the control treatment (p = 0.007) but was not more effective in reducing depression severity. Within-group effects (Cohen's d) at post and at 6 months were as follows: ISI 1.40 and 1.42 (combined treatment), 0.95 and 1.00 (control); MADRS-S 0.97 and 1.12 (combined), 0.88 and 0.89 (control).

Conclusions: CBT-I shows large specific effects on insomnia severity and is superior to control in this regard. Both treatments had similar effects on depression severity, i.e., combining CBT-I with CBT for depression did not enhance outcomes on depression compared to control. We suggest CBT-I should always be offered to patients with insomnia and depression comorbidity, possibly as the first-hand choice. Combining it with a psychological treatment for depression could be too burdening and may not be beneficial.

简介失眠和抑郁是高发疾病,通常同时出现。治疗失眠的认知行为疗法(CBT-I)已被证明对治疗失眠和合并抑郁症有效。然而,目前还不清楚 CBT-I 对抑郁症的影响是特异性的还是非特异性的。此外,CBT-I 治疗后抑郁症状往往仍然过高,这表明需要改进治疗方法。本研究旨在确定在不增加治疗时间的情况下,将 CBT-I 与治疗抑郁症的 CBT 相结合,是否比治疗抑郁症的 CBT 加上安慰剂失眠干预更能减少失眠和抑郁症:方法: 在精神病院开展了一项为期 12 周、随访 6 个月的双盲随机对照试验,采用治疗师指导的互联网治疗方法。患者(N = 126)被医生诊断为失眠症和重度抑郁症。主要结果指标如下:失眠严重程度自评量表(ISI)和蒙哥马利-阿斯伯格抑郁评分量表(MADRS-S):结果:与对照组相比,联合治疗对失眠严重程度有特殊效果(p = 0.007),但在降低抑郁严重程度方面并不更有效。治疗后和 6 个月时的组内效应(Cohen's d)如下:ISI分别为1.40和1.42(联合治疗),0.95和1.00(对照组);MADRS-S分别为0.97和1.12(联合治疗),0.88和0.89(对照组):结论:CBT-I 对失眠严重程度有很大的特效,在这方面优于对照组。两种治疗方法对抑郁症严重程度的影响相似,即与对照组相比,将 CBT-I 与治疗抑郁症的 CBT 相结合并不能提高抑郁症的治疗效果。我们建议,CBT-I 应始终提供给失眠和抑郁并发症患者,并可能作为第一选择。将 CBT-I 与抑郁症的心理治疗相结合可能会造成过重的负担,而且可能不会带来益处。
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引用次数: 0
The Impact of Online Health Information Seeking on Patients, Clinicians, and Patient-Clinician Relationship. 在线健康信息查询对患者、临床医生以及患者与医生关系的影响。
IF 22.8 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-01-01 Epub Date: 2024-03-26 DOI: 10.1159/000538149
Vladan Starcevic
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引用次数: 0
Appreciating the Limits and Opportunities of Meta-Analyses to Understand Complex Psychological Trajectories: Reply to da Silveira et al. 认识元分析在理解复杂心理轨迹方面的局限性和机遇:回复 da Silveira 等人
IF 16.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-01-01 Epub Date: 2024-06-05 DOI: 10.1159/000539166
Amelia J Scott, Ashleigh B Correa, Madelyne A Bisby, Blake F Dear
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引用次数: 0
ICPM News Section. ICPM新闻栏目。
IF 16.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-01-01 Epub Date: 2024-08-28 DOI: 10.1159/000541042
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引用次数: 0
Erratum. 勘误。
IF 16.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-01-01 Epub Date: 2024-08-30 DOI: 10.1159/000540585
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引用次数: 0
Erratum. 勘误。
IF 16.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-01-01 Epub Date: 2024-08-30 DOI: 10.1159/000540975
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引用次数: 0
Should Loneliness Be a Treatment Target? 孤独应该成为治疗目标吗?
IF 16.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-01-01 Epub Date: 2024-09-16 DOI: 10.1159/000540988
Tobias Krieger, Noëmi Seewer
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引用次数: 0
The Role of Online Well-Being Therapy in Overcoming Allostatic Overload in Medical Workers: A Pilot Randomized Controlled Study. 在线幸福疗法在克服医务工作者静力负荷过重方面的作用:一项试点随机对照研究
IF 16.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-01-01 Epub Date: 2024-09-23 DOI: 10.1159/000540924
Xiaolei Liu, Penghui Song, Lu Yin, Kun Wang, Boheng Zhu, Xiaomin Huang, Yanyan Niu, Haixia Leng, Qing Xue, Mao Peng, Baoquan Min, Fangfang Shangguan, Peiran Zhang, Wenfeng Zhao, Huang Wang, Jing Lv, Mei Yang, Ping Wang, Dongning Li, Xiaoling Gao, Kun Feng, Keming Yun, Fiammetta Cosci, Hongxing Wang

Introduction: Stress may lead to allostatic overload. Well-being therapy (WBT) might mitigate it by enhancing psychological well-being and protecting from psychological symptoms. Since no reports are available on the use of WBT in allostatic overload, we evaluated online WBT effects in reducing allostatic overload in medical workers during the coronavirus pandemic.

Methods: Sixty-six participants with allostatic overload were enrolled and randomly assigned to eight sessions of online WBT (n = 32) or eight sessions of an online psychoeducation program on healthy lifestyle (CON) (n = 34). The primary outcome was the prevalence rate of allostatic overload in the two groups at session 8 (T2). Secondary analyses were performed on changes in the PsychoSocial Index (PSI) and Psychological Well-Being (PWB) scales scores at the same time points. Generalized estimating equation models were employed.

Results: The WBT group showed a significantly lower rate of allostatic overload at T2 than the CON group (28.13% vs. 70.59%, p < 0.001); similar results were found at T1, T3, and T4 (p < 0.001). Compared to CON, WBT produced a significant decrease in psychological distress (p < 0.001) and abnormal illness behavior (p = 0.031), as well as a significant improvement in PWB autonomy, environmental mastery, personal growth, positive relations with others, purpose in life, and self-acceptance (p < 0.001).

Conclusion: Online WBT may be an effective non-pharmacological therapeutic strategy for individuals with allostatic overload. These findings need to be further validated in different clinical populations.

导言压力可能会导致异位超负荷。幸福疗法(WBT)可以通过提高心理幸福感和保护心理症状来减轻压力。由于目前还没有关于在异质超负荷中使用 WBT 的报告,我们对在线 WBT 在冠状病毒大流行期间减轻医务工作者异质超负荷的效果进行了评估:我们招募了 66 名患有静态负荷过重的参与者,并将他们随机分配到 8 次在线 WBT 课程(32 人)或 8 次健康生活方式在线心理教育课程(34 人)中。主要结果是两组在第 8 个疗程(T2)时的代谢负荷过重发生率。对同一时间点的社会心理指数(PSI)和心理健康(PWB)量表评分的变化进行次要分析。研究采用了广义估计方程模型:结果:WBT 组在 T2 阶段的代谢负荷过重率明显低于 CON 组(28.13% vs. 70.59%,p < 0.001);T1、T3 和 T4 阶段的结果相似(p < 0.001)。与CON相比,WBT显著减少了心理困扰(p <0.001)和异常疾病行为(p = 0.031),并显著改善了PWB自主性、环境掌握、个人成长、与他人的积极关系、生活目标和自我接纳(p <0.001):在线 WBT 可能是一种有效的非药物治疗策略,适用于异重负荷过重的患者。这些发现还需要在不同的临床人群中进一步验证。
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引用次数: 0
ICPM News Section. ICPM新闻栏目。
IF 22.8 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-01-01 Epub Date: 2024-03-01 DOI: 10.1159/000536596
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引用次数: 0
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Psychotherapy and Psychosomatics
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