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Differentiating Benign from Malignant Cystic Renal Masses using CT Texture-based Machine Learning Algorithms. 利用基于 CT 纹理的机器学习算法区分良性和恶性囊性肾肿块
IF 5.6 Q1 ONCOLOGY Pub Date : 2024-03-01 DOI: 10.1148/rycan.249007
Anupama Ramachandran
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引用次数: 0
Percutaneous Microwave Ablation for Treatment of Retroperitoneal Tumors. 治疗腹膜后肿瘤的经皮微波消融术
IF 5.6 Q1 ONCOLOGY Pub Date : 2024-03-01 DOI: 10.1148/rycan.230080
Annika E Rossebo, Annie M Zlevor, Emily A Knott, Lu Mao, Allison B Couillard, Timothy J Ziemlewicz, J Louis Hinshaw, E Jason Abel, Meghan G Lubner, Erica M Knavel Koepsel, Shane A Wells, Lindsay M Stratchko, Paul F Laeseke, Fred T Lee

Purpose To determine if microwave ablation (MWA) of retroperitoneal tumors can safely provide high rates of local tumor control. Materials and Methods This retrospective study included 19 patients (median age, 65 years [range = 46-78 years]; 13 [68.4%] men and six [31.6%] women) with 29 retroperitoneal tumors treated over 22 MWA procedures. Hydrodissection (0.9% saline with 2% iohexol) was injected in 17 of 22 (77.3%) procedures to protect nontarget anatomy. The primary outcomes evaluated were local tumor progression (LTP) and complication rates. Oncologic outcomes, including overall survival (OS), progression-free survival (PFS), and treatment-free interval (TFI), were examined as secondary outcome measures. Results Median follow-up was 18 months (range = 0.5-113). Hydrodissection was successful in displacing nontarget anatomy in 16 of 17 (94.1%) procedures. The LTP rate was 3.4% (one of 29; 95% CI: 0.1, 17.8) per tumor and 5.3% (one of 19; 95% CI: 0.1, 26.0) per patient. The overall complication rate per patient was 15.8% (three of 19), including two minor complications and one major complication. The OS rate at 1, 2, and 3 years was 81.8%, 81.8%, and 72.7%, respectively, with a median OS estimated at greater than 7 years. There was no evidence of a difference in OS (P = .34) and PFS (P = .56) between patients with renal cell carcinoma (six of 19 [31.6%]) versus other tumors (13 of 19 [68.4%]) and patients treated with no evidence of disease (15 of 22 [68.2%]) versus patients with residual tumors (seven of 22 [31.8%]). Median TFI was 18 months (range = 0.5-108). Conclusion Treatment of retroperitoneal tumors with MWA combined with hydrodissection provided high rates of local control, prolonged systemic therapy-free intervals, and few serious complications. Keywords: Ablation Techniques (ie, Radiofrequency, Thermal, Chemical), Retroperitoneum, Microwave Ablation, Hydrodissection © RSNA, 2024.

目的 确定腹膜后肿瘤的微波消融 (MWA) 是否能安全地提供较高的局部肿瘤控制率。材料和方法 这项回顾性研究纳入了 19 名患者(中位年龄 65 岁 [范围 = 46-78 岁];13 名 [68.4%] 男性和 6 名 [31.6%] 女性),他们患有 29 例腹膜后肿瘤,接受了 22 次微波消融术治疗。在 22 例手术中,有 17 例(77.3%)注射了水切割液(0.9% 生理盐水加 2% 碘海醇),以保护非目标解剖结构。评估的主要结果是局部肿瘤进展(LTP)和并发症发生率。肿瘤学结果,包括总生存期(OS)、无进展生存期(PFS)和无治疗间隔期(TFI),则作为次要结果进行评估。结果 中位随访时间为 18 个月(范围 = 0.5-113)。在 17 例手术中,有 16 例(94.1%)的水切割成功移除了非目标解剖结构。每个肿瘤的 LTP 率为 3.4%(29 例中有 1 例;95% CI:0.1, 17.8),每个患者的 LTP 率为 5.3%(19 例中有 1 例;95% CI:0.1, 26.0)。每位患者的总并发症发生率为 15.8%(19 例中有 3 例),包括 2 例轻微并发症和 1 例严重并发症。1年、2年和3年的OS率分别为81.8%、81.8%和72.7%,中位OS估计超过7年。没有证据表明,肾细胞癌患者(19 例中的 6 例 [31.6%])与其他肿瘤患者(19 例中的 13 例 [68.4%])、无疾病证据患者(22 例中的 15 例 [68.2%])与残留肿瘤患者(22 例中的 7 例 [31.8%])之间的 OS(P = .34)和 PFS(P = .56)存在差异。中位 TFI 为 18 个月(范围 = 0.5-108)。结论 采用MWA联合水动力切除术治疗腹膜后肿瘤,局部控制率高,无系统治疗间隔时间长,严重并发症少。关键词消融技术(即射频、热、化学)、腹膜后、微波消融、水切割 © RSNA, 2024.
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引用次数: 0
Highlighting the Benefits and Disadvantages of Individual Participant Data Meta-Analysis in Radiology. 突出放射学中个体参与者数据元分析的利弊。
IF 5.6 Q1 ONCOLOGY Pub Date : 2024-03-01 DOI: 10.1148/rycan.240018
Andre L F Costa, Sérgio L P C Lopes
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引用次数: 0
Evaluating the Use of ChatGPT to Accurately Simplify Patient-centered Information about Breast Cancer Prevention and Screening. 评估使用 ChatGPT 准确简化以患者为中心的乳腺癌预防和筛查信息。
IF 5.6 Q1 ONCOLOGY Pub Date : 2024-03-01 DOI: 10.1148/rycan.230086
Hana L Haver, Anuj K Gupta, Emily B Ambinder, Manisha Bahl, Eniola T Oluyemi, Jean Jeudy, Paul H Yi

Purpose To evaluate the use of ChatGPT as a tool to simplify answers to common questions about breast cancer prevention and screening. Materials and Methods In this retrospective, exploratory study, ChatGPT was requested to simplify responses to 25 questions about breast cancer to a sixth-grade reading level in March and August 2023. Simplified responses were evaluated for clinical appropriateness. All original and simplified responses were assessed for reading ease on the Flesch Reading Ease Index and for readability on five scales: Flesch-Kincaid Grade Level, Gunning Fog Index, Coleman-Liau Index, Automated Readability Index, and the Simple Measure of Gobbledygook (ie, SMOG) Index. Mean reading ease, readability, and word count were compared between original and simplified responses using paired t tests. McNemar test was used to compare the proportion of responses with adequate reading ease (score of 60 or greater) and readability (sixth-grade level). Results ChatGPT improved mean reading ease (original responses, 46 vs simplified responses, 70; P < .001) and readability (original, grade 13 vs simplified, grade 8.9; P < .001) and decreased word count (original, 193 vs simplified, 173; P < .001). Ninety-two percent (23 of 25) of simplified responses were considered clinically appropriate. All 25 (100%) simplified responses met criteria for adequate reading ease, compared with only two of 25 original responses (P < .001). Two of the 25 simplified responses (8%) met criteria for adequate readability. Conclusion ChatGPT simplified answers to common breast cancer screening and prevention questions by improving the readability by four grade levels, though the potential to produce incorrect information necessitates physician oversight when using this tool. Keywords: Mammography, Screening, Informatics, Breast, Education, Health Policy and Practice, Oncology, Technology Assessment Supplemental material is available for this article. © RSNA, 2023.

目的 评估将 ChatGPT 用作简化乳腺癌预防和筛查常见问题答案的工具的使用情况。材料和方法 在这项回顾性探索研究中,要求 ChatGPT 在 2023 年 3 月和 8 月将 25 个有关乳腺癌问题的回答简化为六年级的阅读水平。对简化后的回答进行了临床适宜性评估。根据 Flesch 阅读容易程度指数和五个量表对所有原始和简化回复的阅读容易程度进行了评估:弗莱什-金凯德等级水平、古宁雾指数、科尔曼-利亚指数、自动可读性指数和简单拗口指数(即 SMOG)。使用配对 t 检验比较了原始答案和简化答案的平均阅读难易度、可读性和字数。McNemar 检验用于比较具有适当阅读难度(60 分或以上)和可读性(六年级水平)的答卷比例。结果 ChatGPT 提高了平均阅读难度(原始答案 46 分,简化答案 70 分;P < .001)和可读性(原始答案 13 级,简化答案 8.9 级;P < .001),减少了字数(原始答案 193 字,简化答案 173 字;P < .001)。92%的简化回复(25 份中的 23 份)被认为符合临床需要。所有 25 份(100%)简化答卷都符合足够易读性的标准,而 25 份原始答卷中只有 2 份符合标准(P < .001)。25 个简化回复中有两个(8%)符合充分易读性标准。结论 ChatGPT 简化了常见的乳腺癌筛查和预防问题的答案,将可读性提高了四个等级,但由于可能会产生错误信息,因此医生在使用该工具时有必要进行监督。关键词乳房 X 线照相术 筛查 信息学 乳腺癌 教育 卫生政策与实践 肿瘤学 技术评估 本文有补充材料。© RSNA, 2023.
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引用次数: 0
Low-Dose Positron Emission Mammography: A Novel, Promising Technique for Breast Cancer Detection. 低剂量正电子发射乳腺放射摄影术:用于乳腺癌检测的一种新型、前景广阔的技术。
IF 5.6 Q1 ONCOLOGY Pub Date : 2024-03-01 DOI: 10.1148/rycan.240006
David S Barreto, Jocelyn A Rapelyea
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引用次数: 0
Screening Breast MRI Effectively Detects Early-Stage Breast Cancer in High-Risk Patients without Prior History of Breast Cancer. 乳腺磁共振成像筛查能有效检测无乳腺癌病史的高危患者中的早期乳腺癌。
IF 5.6 Q1 ONCOLOGY Pub Date : 2024-03-01 DOI: 10.1148/rycan.249005
Brandon K K Fields, Bonnie N Joe
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引用次数: 0
GammaTile: Reshaping Brachytherapy. 伽玛瓷砖:重塑近距离放射治疗。
IF 5.6 Q1 ONCOLOGY Pub Date : 2024-03-01 DOI: 10.1148/rycan.230208
David Casper, Joel Hayden, Mayra Anthony, Nick Matthees, Raza Mushtaq
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引用次数: 0
2023 Manuscript Reviewers: A Note of Thanks. 2023 审稿人:感谢信。
IF 4.4 Pub Date : 2024-03-01 DOI: 10.1148/rycan.240054
Curtis P Langlotz, Gary D Luker
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引用次数: 0
Incidental Ring-hyperenhancing Liver Micronodules at CT Hepatic Arteriography-guided Percutaneous Thermal Ablation of Colorectal Liver Metastases. CT肝动脉造影引导下经皮热消融结直肠肝转移瘤的偶发环形强化肝小结节。
IF 5.6 Q1 ONCOLOGY Pub Date : 2024-03-01 DOI: 10.1148/rycan.230099
Jessica Albuquerque, Yuan-Mao Lin, Iwan Paolucci, Caleb S O'Connor, Ching-Wei Tzeng, Jean-Nicolas Vauthey, Kristy K Brock, Bruno C Odisio

CT during hepatic arteriography (CTHA) is a highly sensitive imaging method for detecting colorectal liver metastases (CLMs), which supports its use during percutaneous thermal liver ablation. In contrast to its high sensitivity, its specificity for incidental small CLMs not detected at preablation cross-sectional imaging is believed to be low given the absence of specific imaging signatures and the common presence of pseudolesions. In this retrospective study of 22 patients (mean age, 55 years ± 10.6 [SD]; 63.6% male, 36.4% female) with CLMs undergoing CTHA-guided microwave percutaneous thermal ablation between November 2017 and October 2022, the authors provided a definition of incidental ring-hyperenhancing liver micronodules (RHLMs) and investigated whether there is a correlation of RHLMs with histologic analysis or intrahepatic tumor progression at imaging follow-up after applying a biomechanical deformable image registration method. The analysis revealed 25 incidental RHLMs in 41.7% (10 of 24) of the CTHA images from the respective guided ablation sessions. Of those, four RHLMs were ablated. Among the remaining 21 RHLMs, 71.4% (15 of 21) were confirmed to be CLM with either histology (n = 3) or imaging follow-up (n = 12). The remaining 28.6% (six of 21) of RHLMs were not observed at follow-up imaging. This suggests that RHLMs at CTHA may be an early indicator of incidental small CLMs. Keywords: Colorectal Neoplasms, Liver, Angiography, CT, Incidental Findings, Ablation Supplemental material is available for this article. © RSNA, 2024.

肝动脉造影(CTHA)是一种检测结直肠肝转移瘤(CLMs)的高灵敏度成像方法,支持在经皮肝热消融术中使用。与高灵敏度形成鲜明对比的是,由于缺乏特异性成像特征和假性灶的普遍存在,该方法对消融前横断面成像未检测到的偶发小CLM的特异性被认为很低。在这项回顾性研究中,有 22 名患者(平均年龄 55 岁 ± 10.6 [SD];63.6% 为男性,36.4%为女性),他们在2017年11月至2022年10月期间接受了CTHA引导下的微波经皮热消融术,作者提供了偶发环状强化肝小结节(RHLMs)的定义,并在应用生物力学可变形图像配准方法后,研究了RHLMs与组织学分析或成像随访时肝内肿瘤进展是否存在相关性。分析结果显示,在各次引导消融治疗的CTHA图像中,41.7%(24张中的10张)的图像中出现了25个偶然的RHLM。其中,4个RHLM被消融。在剩余的 21 个 RHLM 中,71.4%(21 个中的 15 个)经组织学(3 个)或成像随访(12 个)证实为 CLM。其余 28.6% 的 RHLM(21 例中的 6 例)在随访成像中未被观察到。这表明,CTHA上的RHLM可能是偶发小型CLM的早期指标。关键词:大肠肿瘤结直肠肿瘤、肝脏、血管造影、CT、偶然发现、消融 本文有补充材料。© RSNA, 2024.
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引用次数: 0
Hyperpolarized 13C Pyruvate MRI: An Important Window into Tumor Metabolism. 超极化 13C 丙酮酸核磁共振成像:了解肿瘤代谢的重要窗口
IF 5.6 Q1 ONCOLOGY Pub Date : 2024-03-01 DOI: 10.1148/rycan.240004
Michael A Ohliger
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引用次数: 0
期刊
Radiology. Imaging cancer
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