Pub Date : 2024-09-01Epub Date: 2024-03-15DOI: 10.1177/00333549241230479
Heleen Vermandere, Gisela Martínez-Silva, Santiago Aguilera-Mijares, Araczy Martínez-Dávalos, Sergio Bautista-Arredondo
Objectives: Screening tools in which participants self-report sexual behaviors can identify people at risk of HIV acquisition for enrollment in preexposure prophylaxis (PrEP). We compared enrollment outcomes (ie, receiving PrEP vs being excluded by a counselor or declining PrEP) in Mexico's PrEP demonstration project and evaluated the validity of a 4-criteria PrEP eligibility tool in which participants self-reported risk behavior-having condomless anal sex, transactional sex, a partner living with HIV, or a sexually transmitted infection-as compared with PrEP eligibility assessed by a counselor.
Methods: We recruited men who have sex with men and transwomen who were offered PrEP services in Mexico. We characterized participants according to enrollment outcome and identified underlying factors through logistic regression analyses. We calculated the sensitivity and specificity of the self-reported risk criteria, using the counselor's risk assessment as the point of reference.
Results: Of 2460 participants, 2323 (94%) had risk criteria of HIV acquisition according to the 4-criteria tool; 1701 (73%) received PrEP, 247 (11%) were excluded by a counselor, and 351 (15%) declined PrEP despite being considered eligible by the counselor. Participants who were excluded or who declined PrEP were less likely to report HIV risk behaviors than those who received PrEP, and participants who declined PrEP were more likely to be transwomen (vs men who have sex with men) and aged ≤25 years (vs >25 y). The 4-criteria risk tool had high sensitivity (98.6%) and low specificity (29.8%).
Conclusion: The screening tool identified most participants at risk of HIV acquisition, but counselors' assessment helped refine the decision for enrollment in PrEP by excluding those with low risk. Public health strategies are needed to enhance enrollment in PrEP among some groups.
目的:通过参与者自我报告性行为的筛查工具,可以确定哪些人有感染 HIV 的风险,并将其纳入暴露前预防疗法 (PrEP)。我们比较了墨西哥 PrEP 示范项目的入组结果(即接受 PrEP 与被咨询师排除在外或拒绝接受 PrEP),并评估了 4 项 PrEP 资格标准工具的有效性,该工具由参与者自我报告风险行为--无套肛交、性交易、伴侣感染 HIV 或性传播感染--与咨询师评估的 PrEP 资格进行比较:我们在墨西哥招募了获得 PrEP 服务的男男性行为者和变性女性。我们根据注册结果对参与者进行了特征描述,并通过逻辑回归分析确定了潜在因素。我们以咨询师的风险评估为参考点,计算了自我报告风险标准的敏感性和特异性:在 2460 名参与者中,有 2323 人(94%)根据 4 项标准工具确定了感染 HIV 的风险标准;1701 人(73%)接受了 PrEP,247 人(11%)被咨询师排除在外,351 人(15%)拒绝接受 PrEP,尽管咨询师认为他们符合条件。与接受 PrEP 的参与者相比,被排除在外或拒绝接受 PrEP 的参与者报告 HIV 风险行为的可能性较低,拒绝接受 PrEP 的参与者更有可能是变性女性(与男男性行为者相比)和年龄小于 25 岁(与大于 25 岁相比)。4项标准风险工具的灵敏度高(98.6%),特异性低(29.8%):结论:筛查工具识别出了大多数有感染 HIV 风险的参与者,但咨询师的评估排除了低风险者,有助于完善加入 PrEP 的决定。需要采取公共卫生策略来提高某些群体的 PrEP 注册率。
{"title":"Evaluating the Screening and Enrollment of People at Risk of HIV in Mexico's Preexposure Prophylaxis Demonstration Project, 2018-2020.","authors":"Heleen Vermandere, Gisela Martínez-Silva, Santiago Aguilera-Mijares, Araczy Martínez-Dávalos, Sergio Bautista-Arredondo","doi":"10.1177/00333549241230479","DOIUrl":"10.1177/00333549241230479","url":null,"abstract":"<p><strong>Objectives: </strong>Screening tools in which participants self-report sexual behaviors can identify people at risk of HIV acquisition for enrollment in preexposure prophylaxis (PrEP). We compared enrollment outcomes (ie, receiving PrEP vs being excluded by a counselor or declining PrEP) in Mexico's PrEP demonstration project and evaluated the validity of a 4-criteria PrEP eligibility tool in which participants self-reported risk behavior-having condomless anal sex, transactional sex, a partner living with HIV, or a sexually transmitted infection-as compared with PrEP eligibility assessed by a counselor.</p><p><strong>Methods: </strong>We recruited men who have sex with men and transwomen who were offered PrEP services in Mexico. We characterized participants according to enrollment outcome and identified underlying factors through logistic regression analyses. We calculated the sensitivity and specificity of the self-reported risk criteria, using the counselor's risk assessment as the point of reference.</p><p><strong>Results: </strong>Of 2460 participants, 2323 (94%) had risk criteria of HIV acquisition according to the 4-criteria tool; 1701 (73%) received PrEP, 247 (11%) were excluded by a counselor, and 351 (15%) declined PrEP despite being considered eligible by the counselor. Participants who were excluded or who declined PrEP were less likely to report HIV risk behaviors than those who received PrEP, and participants who declined PrEP were more likely to be transwomen (vs men who have sex with men) and aged ≤25 years (vs >25 y). The 4-criteria risk tool had high sensitivity (98.6%) and low specificity (29.8%).</p><p><strong>Conclusion: </strong>The screening tool identified most participants at risk of HIV acquisition, but counselors' assessment helped refine the decision for enrollment in PrEP by excluding those with low risk. Public health strategies are needed to enhance enrollment in PrEP among some groups.</p>","PeriodicalId":20793,"journal":{"name":"Public Health Reports","volume":" ","pages":"606-614"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11344982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140140630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01Epub Date: 2024-03-19DOI: 10.1177/00333549241236629
Khaleel S Hussaini, Romeo Galang, Rui Li
Objectives: Evidence is limited on differences in cesarean rates for nulliparous, term, singleton, vertex (NTSV) births across racial and ethnic groups at the national and state level during the COVID-19 pandemic. We assessed changes in levels and trends of NTSV cesarean rates before and after stay-at-home orders (SAHOs) were implemented in the United States (1) overall, (2) by racial and ethnic groups, and (3) by 50 US states from January 2017 through December 2021.
Methods: We used birth certificate data from 2017 through 2021, restricted to hospital births, to calculate monthly NTSV cesarean rates for the United States and for racial and ethnic groups and to calculate quarterly NTSV cesarean rates for the 50 states. We used interrupted time-series analysis to measure changes in NTSV cesarean rates before and after implementation of SAHOs (March 1 through May 31, 2020).
Results: Of 6 022 552 NTSV hospital births, 1 579 645 (26.2%) were cesarean births. Before implementation of SAHOs, NTSV cesarean rates were declining in the United States overall; were declining among births to non-Hispanic Asian, non-Hispanic Black, Hispanic, and non-Hispanic White women; and were declining in 6 states. During the first month of implementation of SAHOs in May 2020, monthly NTSV rates increased in the United States by 0.55%. Monthly NTSV rates increased by 1.20% among non-Hispanic Black women, 0.90% among Hispanic women, and 0.28% among non-Hispanic White women; quarterly NTSV rates increased in 6 states.
Conclusion: In addition to emergency preparedness planning, hospital monitoring, and reporting of NTSV cesarean rates to increase provider awareness, reallocation and prioritization of resources may help to identify potential strains on health care systems during public health emergencies such as the COVID-19 pandemic.
{"title":"Differences in Cesarean Rates for Nulliparous, Term, Singleton, Vertex Births Among Racial and Ethnic Groups and States Before and After Stay-at-Home Orders During the COVID-19 Pandemic, United States, 2017-2021.","authors":"Khaleel S Hussaini, Romeo Galang, Rui Li","doi":"10.1177/00333549241236629","DOIUrl":"10.1177/00333549241236629","url":null,"abstract":"<p><strong>Objectives: </strong>Evidence is limited on differences in cesarean rates for nulliparous, term, singleton, vertex (NTSV) births across racial and ethnic groups at the national and state level during the COVID-19 pandemic. We assessed changes in levels and trends of NTSV cesarean rates before and after stay-at-home orders (SAHOs) were implemented in the United States (1) overall, (2) by racial and ethnic groups, and (3) by 50 US states from January 2017 through December 2021.</p><p><strong>Methods: </strong>We used birth certificate data from 2017 through 2021, restricted to hospital births, to calculate monthly NTSV cesarean rates for the United States and for racial and ethnic groups and to calculate quarterly NTSV cesarean rates for the 50 states. We used interrupted time-series analysis to measure changes in NTSV cesarean rates before and after implementation of SAHOs (March 1 through May 31, 2020).</p><p><strong>Results: </strong>Of 6 022 552 NTSV hospital births, 1 579 645 (26.2%) were cesarean births. Before implementation of SAHOs, NTSV cesarean rates were declining in the United States overall; were declining among births to non-Hispanic Asian, non-Hispanic Black, Hispanic, and non-Hispanic White women; and were declining in 6 states. During the first month of implementation of SAHOs in May 2020, monthly NTSV rates increased in the United States by 0.55%. Monthly NTSV rates increased by 1.20% among non-Hispanic Black women, 0.90% among Hispanic women, and 0.28% among non-Hispanic White women; quarterly NTSV rates increased in 6 states.</p><p><strong>Conclusion: </strong>In addition to emergency preparedness planning, hospital monitoring, and reporting of NTSV cesarean rates to increase provider awareness, reallocation and prioritization of resources may help to identify potential strains on health care systems during public health emergencies such as the COVID-19 pandemic.</p>","PeriodicalId":20793,"journal":{"name":"Public Health Reports","volume":" ","pages":"615-625"},"PeriodicalIF":3.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11344689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140176157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-31DOI: 10.1177/00333549241269483
Amanda D Tran, Alice E White, Rachel H Jervis, Ingrid Hewitson, Elaine J Scallan Walter
Objectives: Although enteric disease case interviews are critical for control measures and education, not all case-patients are interviewed. We evaluated systematic differences between people with an enteric disease in Colorado who were and were not interviewed to identify ways to increase response rates and reduce biases in the surveillance data used to guide public health interventions.
Methods: We obtained data from the Colorado Electronic Disease Reporting System from March 1, 2017, through December 31, 2019. Among case-patients not interviewed and interviewed, we used univariate analyses to describe sociodemographic characteristics, timing of contact attempts, and effect of additional funding.
Results: As compared with case-patients who were interviewed, case-patients who were not interviewed were significantly more likely to be aged 18 to 39 years (35.7% vs 31.7%; P < .001); identify as male, Hispanic, or Black; be experiencing homelessness or hospitalization; reside in rural/frontier areas or an institution; or live in areas with lower levels of education, life expectancy, and income. Time to first contact attempt was longer for case-patients who were not interviewed than for those who were (mean days from specimen collection to first contact attempt, 9.8 vs 6.8; P < .001). Residing in a jurisdiction with additional funding for interviewing was associated with increased interview rates (87.7% vs 68.8%) and timeliness of public health report and first contact attempt (2.3 vs 4.4 days; P < .001).
Conclusion: Findings can guide efforts to improve response rates in groups least likely to be interviewed, resulting in reduced biases in surveillance data, better disease mitigation, and increased efficiency in case investigations. Timeliness of case interviews and additional funding to conduct case investigations were factors in increasing response rates.
目标:尽管肠道疾病病例访谈对于控制措施和教育至关重要,但并非所有病例患者都接受了访谈。我们评估了科罗拉多州接受和未接受访谈的肠道疾病患者之间的系统性差异,以确定提高响应率和减少用于指导公共卫生干预的监测数据偏差的方法:我们从科罗拉多州电子疾病报告系统中获取了 2017 年 3 月 1 日至 2019 年 12 月 31 日期间的数据。在未接受访谈和接受访谈的病例患者中,我们使用单变量分析来描述社会人口学特征、尝试联系的时间以及额外资金的影响:结果:与接受访谈的病例患者相比,未接受访谈的病例患者年龄在 18 岁至 39 岁之间的比例明显更高(35.7% 对 31.7%;P P P P 结论:研究结果可以指导我们提高响应率的工作:研究结果可以指导我们努力提高最不可能接受访谈的群体的回复率,从而减少监测数据的偏差,更好地缓解疾病,并提高病例调查的效率。病例访谈的及时性和开展病例调查的额外资金是提高应答率的因素。
{"title":"Characteristics of People Who Do Not Complete a Public Health Interview: An Assessment of Colorado Enteric Disease Surveillance Data.","authors":"Amanda D Tran, Alice E White, Rachel H Jervis, Ingrid Hewitson, Elaine J Scallan Walter","doi":"10.1177/00333549241269483","DOIUrl":"10.1177/00333549241269483","url":null,"abstract":"<p><strong>Objectives: </strong>Although enteric disease case interviews are critical for control measures and education, not all case-patients are interviewed. We evaluated systematic differences between people with an enteric disease in Colorado who were and were not interviewed to identify ways to increase response rates and reduce biases in the surveillance data used to guide public health interventions.</p><p><strong>Methods: </strong>We obtained data from the Colorado Electronic Disease Reporting System from March 1, 2017, through December 31, 2019. Among case-patients not interviewed and interviewed, we used univariate analyses to describe sociodemographic characteristics, timing of contact attempts, and effect of additional funding.</p><p><strong>Results: </strong>As compared with case-patients who were interviewed, case-patients who were not interviewed were significantly more likely to be aged 18 to 39 years (35.7% vs 31.7%; <i>P</i> < .001); identify as male, Hispanic, or Black; be experiencing homelessness or hospitalization; reside in rural/frontier areas or an institution; or live in areas with lower levels of education, life expectancy, and income. Time to first contact attempt was longer for case-patients who were not interviewed than for those who were (mean days from specimen collection to first contact attempt, 9.8 vs 6.8; <i>P</i> < .001). Residing in a jurisdiction with additional funding for interviewing was associated with increased interview rates (87.7% vs 68.8%) and timeliness of public health report and first contact attempt (2.3 vs 4.4 days; <i>P</i> < .001).</p><p><strong>Conclusion: </strong>Findings can guide efforts to improve response rates in groups least likely to be interviewed, resulting in reduced biases in surveillance data, better disease mitigation, and increased efficiency in case investigations. Timeliness of case interviews and additional funding to conduct case investigations were factors in increasing response rates.</p>","PeriodicalId":20793,"journal":{"name":"Public Health Reports","volume":" ","pages":"333549241269483"},"PeriodicalIF":3.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142111367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-27DOI: 10.1177/00333549241271728
Stacy Davis, Devin English, Stephanie Shiau, Rajita Bhavaraju, Shauna Downs, Gwyneth M Eliasson, Kristen D Krause, Emily V Merchant, Tess Olsson, Michelle M Ruidíaz-Santiago, Nimit N Shah, Laura E Liang, Teri Lassiter
We critically reviewed the motivations, processes, and implementation methods underlying a faculty-driven diversity, equity, and inclusion (DEI) curriculum self-reflection project in the Rutgers School of Public Health. This case study offers guidance on a curriculum self-reflection tool that was developed through the school's Curriculum Committee to promote DEI throughout the school's curricula. We review the key steps in this process and the unique aspects of developing and implementing such evaluations within higher education. The study draws on faculty experience, was informed by students and staff within the Curriculum Committee, and builds on existing knowledge and tools. A flexible 6-step framework-including guiding principles and strategic approaches to planning, developing, and implementing a DEI curriculum self-assessment-is provided to assist instructors, curriculum committees, DEI groups, and academic leaders at schools of public health interested in refining their courses and curricula. Academic units experience contextual challenges, and while each is at a different stage in curriculum reform, our findings provide lessons about integrating the assessment of DEI in school curriculum in a systematic and iterative way. Our approach can be applied to diverse academic settings, including those experiencing similar implementation challenges.
我们对罗格斯大学公共卫生学院由教师推动的多样性、公平性和包容性(DEI)课程自我反思项目的动机、过程和实施方法进行了严格审查。本案例研究为课程自我反思工具提供了指导,该工具是通过学校的课程委员会开发的,目的是在学校的整个课程中促进多元化、公平和包容(DEI)。我们回顾了这一过程中的关键步骤,以及在高等教育中开发和实施此类评估的独特之处。这项研究借鉴了教师的经验,听取了课程委员会学生和教职员工的意见,并以现有的知识和工具为基础。本研究提供了一个灵活的 6 步框架,包括规划、开发和实施发展与教育课程自我评估的指导原则和战略方法,以帮助公共卫生学院的教师、课程委员会、发展与教育小组以及有兴趣完善其课程和教学大纲的学术带头人。各学术单位都面临着不同的挑战,虽然每个单位在课程改革中都处于不同的阶段,但我们的研究结果为以系统和迭代的方式在学校课程中整合 DEI 评估提供了经验。我们的方法可以应用于不同的学术环境,包括那些遇到类似实施挑战的学术环境。
{"title":"Developing and Implementing a Diversity, Equity, and Inclusion Curriculum Self-reflection Process at a School of Public Health.","authors":"Stacy Davis, Devin English, Stephanie Shiau, Rajita Bhavaraju, Shauna Downs, Gwyneth M Eliasson, Kristen D Krause, Emily V Merchant, Tess Olsson, Michelle M Ruidíaz-Santiago, Nimit N Shah, Laura E Liang, Teri Lassiter","doi":"10.1177/00333549241271728","DOIUrl":"10.1177/00333549241271728","url":null,"abstract":"<p><p>We critically reviewed the motivations, processes, and implementation methods underlying a faculty-driven diversity, equity, and inclusion (DEI) curriculum self-reflection project in the Rutgers School of Public Health. This case study offers guidance on a curriculum self-reflection tool that was developed through the school's Curriculum Committee to promote DEI throughout the school's curricula. We review the key steps in this process and the unique aspects of developing and implementing such evaluations within higher education. The study draws on faculty experience, was informed by students and staff within the Curriculum Committee, and builds on existing knowledge and tools. A flexible 6-step framework-including guiding principles and strategic approaches to planning, developing, and implementing a DEI curriculum self-assessment-is provided to assist instructors, curriculum committees, DEI groups, and academic leaders at schools of public health interested in refining their courses and curricula. Academic units experience contextual challenges, and while each is at a different stage in curriculum reform, our findings provide lessons about integrating the assessment of DEI in school curriculum in a systematic and iterative way. Our approach can be applied to diverse academic settings, including those experiencing similar implementation challenges.</p>","PeriodicalId":20793,"journal":{"name":"Public Health Reports","volume":" ","pages":"333549241271728"},"PeriodicalIF":3.0,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142073661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-27DOI: 10.1177/00333549241269497
Katharine L Thomas, Tricia A Aden, Patricia A Blevins, Amanda J Raziano, Tyler Wolford, Margaret A Honein, Julie M Villanueva
Objectives: The Laboratory Response Network (LRN) consists of US and international laboratories that respond to public health emergencies, such as biothreats. We used a qualitative approach to assess the successes and challenges of the LRN during the initial 10 weeks of the 2022 mpox outbreak (May 17-July 31, 2022).
Methods: We conducted 9 unstructured interviews, which included 3 interviews with subject matter experts from the Centers for Disease Control and Prevention (CDC) and 6 interviews with state and local public health laboratories and epidemiologists and Association of Public Health Laboratories (APHL) staff. We asked guiding questions on investments in preparedness, successes, and challenges during the initial mpox response and asked for suggestions to improve future LRN responses to infectious disease outbreaks. We also reviewed data from 2 contemporaneous APHL surveys conducted in June and July 2022 in 84 LRN public health laboratories.
Results: Notable successes included availability of an assay that had received clearance from the US Food and Drug Administration (FDA) for testing orthopoxviruses (non-variola Orthopoxvirus [NVO] assay) and a trained workforce; strong relationships among FDA, CDC, and the LRN; and strong communications between LRN laboratories and CDC. Challenges included variability among LRN laboratories in self-reported testing capacity, barriers to accessing the NVO assay for health care providers, and gaps in LRN function during surges of testing needs.
Conclusions: The LRN system plays an essential role in the response to emerging infectious disease outbreaks in the United States. Lessons learned from the LRN's initial response to the mpox outbreak can help guide improvements to better position the LRN for future responses, including continued engagement with health care providers, commercial laboratories, and laboratories in health care settings.
{"title":"Evaluation of the Laboratory Response Network and Testing Access During the First 10 Weeks of the Mpox Response, United States, May 17-July 31, 2022.","authors":"Katharine L Thomas, Tricia A Aden, Patricia A Blevins, Amanda J Raziano, Tyler Wolford, Margaret A Honein, Julie M Villanueva","doi":"10.1177/00333549241269497","DOIUrl":"10.1177/00333549241269497","url":null,"abstract":"<p><strong>Objectives: </strong>The Laboratory Response Network (LRN) consists of US and international laboratories that respond to public health emergencies, such as biothreats. We used a qualitative approach to assess the successes and challenges of the LRN during the initial 10 weeks of the 2022 mpox outbreak (May 17-July 31, 2022).</p><p><strong>Methods: </strong>We conducted 9 unstructured interviews, which included 3 interviews with subject matter experts from the Centers for Disease Control and Prevention (CDC) and 6 interviews with state and local public health laboratories and epidemiologists and Association of Public Health Laboratories (APHL) staff. We asked guiding questions on investments in preparedness, successes, and challenges during the initial mpox response and asked for suggestions to improve future LRN responses to infectious disease outbreaks. We also reviewed data from 2 contemporaneous APHL surveys conducted in June and July 2022 in 84 LRN public health laboratories.</p><p><strong>Results: </strong>Notable successes included availability of an assay that had received clearance from the US Food and Drug Administration (FDA) for testing orthopoxviruses (non-variola <i>Orthopoxvirus</i> [NVO] assay) and a trained workforce; strong relationships among FDA, CDC, and the LRN; and strong communications between LRN laboratories and CDC. Challenges included variability among LRN laboratories in self-reported testing capacity, barriers to accessing the NVO assay for health care providers, and gaps in LRN function during surges of testing needs.</p><p><strong>Conclusions: </strong>The LRN system plays an essential role in the response to emerging infectious disease outbreaks in the United States. Lessons learned from the LRN's initial response to the mpox outbreak can help guide improvements to better position the LRN for future responses, including continued engagement with health care providers, commercial laboratories, and laboratories in health care settings.</p>","PeriodicalId":20793,"journal":{"name":"Public Health Reports","volume":" ","pages":"333549241269497"},"PeriodicalIF":3.0,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142073662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01Epub Date: 2024-02-15DOI: 10.1177/00333549231223140
Tina J Benoit, Yun Kim, Yangyang Deng, Zheng Li, Lee Harding, Ryan Wiegand, Xiaoyi Deng, Jefferson M Jones, Iachan Ronaldo, Kristie E N Clarke
Objective: We conducted a national US study of SARS-CoV-2 seroprevalence by Social Vulnerability Index (SVI) that included pediatric data and compared the Delta and Omicron periods during the COVID-19 pandemic. The objective of the current study was to assess the association between SVI and seroprevalence of infection-induced SARS-CoV-2 antibodies by period (Delta vs Omicron) and age group.
Methods: We used results of infection-induced SARS-CoV-2 antibody assays of clinical sera specimens (N = 406 469) from 50 US states from September 2021 through February 2022 to estimate seroprevalence overall and by county SVI tercile. Bivariate analyses and multilevel logistic regression models assessed the association of seropositivity with SVI and its themes by age group (0-17, ≥18 y) and period (Delta: September-November 2021; Omicron: December 2021-February 2022).
Results: Aggregate infection-induced SARS-CoV-2 antibody seroprevalence increased at all 3 SVI levels; it ranged from 25.8% to 33.5% in September 2021 and from 53.1% to 63.5% in February 2022. Of the 4 SVI themes, socioeconomic status had the strongest association with seroprevalence. During the Delta period, we found significantly more infections per reported case among people living in a county with high SVI (odds ratio [OR] = 2.76; 95% CI, 2.31-3.21) than in a county with low SVI (OR = 1.65; 95% CI, 1.33-1.97); we found no significant difference during the Omicron period. Otherwise, findings were consistent across subanalyses by age group and period.
Conclusions: Among both children and adults, and during both the Delta and Omicron periods, counties with high SVI had significantly higher SARS-CoV-2 antibody seroprevalence than counties with low SVI did. These disparities reinforce SVI's value in identifying communities that need tailored prevention efforts during public health emergencies and resources to recover from their effects.
目的:我们在美国开展了一项按社会脆弱性指数(SVI)划分的 SARS-CoV-2 血清流行率的全国性研究,其中包括儿科数据,并对 COVID-19 大流行期间的 Delta 和 Omicron 阶段进行了比较。本研究的目的是按时期(Delta 与 Omicron)和年龄组评估 SVI 与感染诱发的 SARS-CoV-2 抗体血清流行率之间的关联:我们利用 2021 年 9 月至 2022 年 2 月期间美国 50 个州的临床血清标本(N = 406 469)的感染诱导 SARS-CoV-2 抗体检测结果来估算总体血清流行率和各县 SVI 三元组血清流行率。双变量分析和多层次逻辑回归模型评估了血清阳性与 SVI 的相关性,并按年龄组(0-17 岁,≥18 岁)和时间段(Delta:2021 年 9 月至 11 月;Omicron:2021 年 12 月至 2022 年 2 月)对其主题进行了分析:结果:在所有 3 个 SVI 水平上,感染引起的 SARS-CoV-2 抗体血清阳性反应率都有所上升;2021 年 9 月为 25.8%-33.5%,2022 年 2 月为 53.1%-63.5%。在 4 个 SVI 主题中,社会经济地位与血清流行率的关系最为密切。在德尔塔期间,我们发现生活在高 SVI 县的人每报告一例感染病例的几率 [OR] = 2.76;95% CI,2.31-3.21)明显高于生活在低 SVI 县的人每报告一例感染病例的几率(OR = 1.65;95% CI,1.33-1.97);在欧米克隆期间,我们没有发现显著差异。除此之外,不同年龄组和不同时期的子分析结果是一致的:结论:在儿童和成人中,在德尔塔期和奥密克隆期,SVI 高的县的 SARS-CoV-2 抗体血清流行率明显高于 SVI 低的县。这些差异加强了 SVI 的价值,它可以确定在公共卫生突发事件期间需要有针对性的预防工作的社区,以及需要从其影响中恢复的资源。
{"title":"Association Between Social Vulnerability and SARS-CoV-2 Seroprevalence in Specimens Collected From Commercial Laboratories, United States, September 2021-February 2022.","authors":"Tina J Benoit, Yun Kim, Yangyang Deng, Zheng Li, Lee Harding, Ryan Wiegand, Xiaoyi Deng, Jefferson M Jones, Iachan Ronaldo, Kristie E N Clarke","doi":"10.1177/00333549231223140","DOIUrl":"10.1177/00333549231223140","url":null,"abstract":"<p><strong>Objective: </strong>We conducted a national US study of SARS-CoV-2 seroprevalence by Social Vulnerability Index (SVI) that included pediatric data and compared the Delta and Omicron periods during the COVID-19 pandemic. The objective of the current study was to assess the association between SVI and seroprevalence of infection-induced SARS-CoV-2 antibodies by period (Delta vs Omicron) and age group.</p><p><strong>Methods: </strong>We used results of infection-induced SARS-CoV-2 antibody assays of clinical sera specimens (N = 406 469) from 50 US states from September 2021 through February 2022 to estimate seroprevalence overall and by county SVI tercile. Bivariate analyses and multilevel logistic regression models assessed the association of seropositivity with SVI and its themes by age group (0-17, ≥18 y) and period (Delta: September-November 2021; Omicron: December 2021-February 2022).</p><p><strong>Results: </strong>Aggregate infection-induced SARS-CoV-2 antibody seroprevalence increased at all 3 SVI levels; it ranged from 25.8% to 33.5% in September 2021 and from 53.1% to 63.5% in February 2022. Of the 4 SVI themes, socioeconomic status had the strongest association with seroprevalence. During the Delta period, we found significantly more infections per reported case among people living in a county with high SVI (odds ratio [OR] = 2.76; 95% CI, 2.31-3.21) than in a county with low SVI (OR = 1.65; 95% CI, 1.33-1.97); we found no significant difference during the Omicron period. Otherwise, findings were consistent across subanalyses by age group and period.</p><p><strong>Conclusions: </strong>Among both children and adults, and during both the Delta and Omicron periods, counties with high SVI had significantly higher SARS-CoV-2 antibody seroprevalence than counties with low SVI did. These disparities reinforce SVI's value in identifying communities that need tailored prevention efforts during public health emergencies and resources to recover from their effects.</p>","PeriodicalId":20793,"journal":{"name":"Public Health Reports","volume":" ","pages":"501-511"},"PeriodicalIF":3.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11284970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139735977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01Epub Date: 2023-11-13DOI: 10.1177/00333549231206404
Amanda Monroy, Jennifer Berry, Selene Brambl, Jennie Mullins, Theresa A Cullen
In the United States, persistent health disparities and preexisting gaps in local public health infrastructure led to disproportionate effects of COVID-19 across populations at high risk of COVID-19-related morbidity and mortality. In Pima County, Arizona, equity-centered local government engagement and policy action, multipronged community-based responses, and expansion of historically underfunded local public health infrastructure improved equitable outcomes and addressed multiple systemic factors. This case study examined Pima County's 3-pronged public health response to COVID-19 using an equity-based approach. As a result, COVID-19 was the third leading cause of death in Pima County in 2021, compared with being the leading cause of death in Arizona. Strong political support from local elected officials created the authorizing environment for the Pima County Health Department to advance health equity. Passage of a resolution in December 2020, which framed the racial and ethnic health and socioeconomic inequities as a public health crisis, supported innovation and fostered the creation of an Office of Health Equity, a public health policy program, and a data and informatics program. New structures for community engagement were formed, including an ethics committee and a community advisory committee, to ensure a formalized process for community participation in public health actions, during and after the pandemic response. Key lessons learned included (1) the importance of local government support, codified to allow implementation of creative strategies; (2) opening avenues for community voice and engagement in planning and implementation to respond in areas of greatest need; and (3) having flexible funding to sustain an equitable response.
{"title":"Ensuring an Equitable Response to the COVID-19 Pandemic in Pima County, Arizona, Through Local Political Support and Policy Action.","authors":"Amanda Monroy, Jennifer Berry, Selene Brambl, Jennie Mullins, Theresa A Cullen","doi":"10.1177/00333549231206404","DOIUrl":"10.1177/00333549231206404","url":null,"abstract":"<p><p>In the United States, persistent health disparities and preexisting gaps in local public health infrastructure led to disproportionate effects of COVID-19 across populations at high risk of COVID-19-related morbidity and mortality. In Pima County, Arizona, equity-centered local government engagement and policy action, multipronged community-based responses, and expansion of historically underfunded local public health infrastructure improved equitable outcomes and addressed multiple systemic factors. This case study examined Pima County's 3-pronged public health response to COVID-19 using an equity-based approach. As a result, COVID-19 was the third leading cause of death in Pima County in 2021, compared with being the leading cause of death in Arizona. Strong political support from local elected officials created the authorizing environment for the Pima County Health Department to advance health equity. Passage of a resolution in December 2020, which framed the racial and ethnic health and socioeconomic inequities as a public health crisis, supported innovation and fostered the creation of an Office of Health Equity, a public health policy program, and a data and informatics program. New structures for community engagement were formed, including an ethics committee and a community advisory committee, to ensure a formalized process for community participation in public health actions, during and after the pandemic response. Key lessons learned included (1) the importance of local government support, codified to allow implementation of creative strategies; (2) opening avenues for community voice and engagement in planning and implementation to respond in areas of greatest need; and (3) having flexible funding to sustain an equitable response.</p>","PeriodicalId":20793,"journal":{"name":"Public Health Reports","volume":" ","pages":"16S-22S"},"PeriodicalIF":3.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11339671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92156268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01Epub Date: 2024-01-24DOI: 10.1177/00333549231223707
Frank Spesia, Nancy Swigonski, Cassy White, Mark D Fox, Brett Enneking
Childhood psychosocial experiences can have a lifelong effect on health. These experiences can be measured together as positive and adverse childhood experiences or individually as positive childhood experiences (PCEs) or adverse childhood experiences. Most research on PCEs has focused on how PCEs promote health outcomes. However, limited research has been conducted on the prevalence of PCEs among adolescents in local areas served by public health departments. The St. Joseph County Department of Health developed a study to test the feasibility of surveillance of PCEs through local public health departments and to establish a prevalence for PCE exposure among a population of urban public-school students in Indiana. We conducted a survey in spring 2022 that collected demographic information on students at 2 high schools and 1 middle school and assessed exposure to PCEs. We assessed prevalence of PCEs on a 5-point Likert scale (0 = never, 1 = rarely, 2 = sometimes, 3 = usually, 4 = always). PCE scores were grouped into low (0-2), medium (3-5), and high (6 or 7). The prevalence of individual PCE items ranged from 35.6% to 86.8%. Among 798 respondents, 189 (23.7%) reported low PCE scores, 396 (49.6%) reported medium scores, and 213 (26.7%) reported high scores. This research demonstrates the feasibility of school-based PCE surveillance and establishes a baseline prevalence of PCE exposure among a population of middle and high school students. These methods are applicable to different contexts and can provide both local health departments and school systems with a new tool to address adverse childhood experiences.
{"title":"Leveraging Public Health and Public School Partnerships for Local Surveillance of Positive Childhood Experiences.","authors":"Frank Spesia, Nancy Swigonski, Cassy White, Mark D Fox, Brett Enneking","doi":"10.1177/00333549231223707","DOIUrl":"10.1177/00333549231223707","url":null,"abstract":"<p><p>Childhood psychosocial experiences can have a lifelong effect on health. These experiences can be measured together as positive and adverse childhood experiences or individually as positive childhood experiences (PCEs) or adverse childhood experiences. Most research on PCEs has focused on how PCEs promote health outcomes. However, limited research has been conducted on the prevalence of PCEs among adolescents in local areas served by public health departments. The St. Joseph County Department of Health developed a study to test the feasibility of surveillance of PCEs through local public health departments and to establish a prevalence for PCE exposure among a population of urban public-school students in Indiana. We conducted a survey in spring 2022 that collected demographic information on students at 2 high schools and 1 middle school and assessed exposure to PCEs. We assessed prevalence of PCEs on a 5-point Likert scale (0 = never, 1 = rarely, 2 = sometimes, 3 = usually, 4 = always). PCE scores were grouped into low (0-2), medium (3-5), and high (6 or 7). The prevalence of individual PCE items ranged from 35.6% to 86.8%. Among 798 respondents, 189 (23.7%) reported low PCE scores, 396 (49.6%) reported medium scores, and 213 (26.7%) reported high scores. This research demonstrates the feasibility of school-based PCE surveillance and establishes a baseline prevalence of PCE exposure among a population of middle and high school students. These methods are applicable to different contexts and can provide both local health departments and school systems with a new tool to address adverse childhood experiences.</p>","PeriodicalId":20793,"journal":{"name":"Public Health Reports","volume":" ","pages":"425-431"},"PeriodicalIF":3.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11284967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01Epub Date: 2023-11-13DOI: 10.1177/00333549231204043
Saira Nawaz, Kyle J Moon, Francis Anagbonu, Anne Trinh, Lizette Escobedo, Gloria Itzel Montiel
Objectives: The 12-month vaccination campaign ¡Ándale! ¿Qué Esperas? was launched to increase COVID-19 vaccination rates in Latinx populations in California by expanding community outreach. The objectives of this evaluation were to (1) determine predictors of vaccination rates and (2) identify barriers to vaccination and potential solutions.
Methods: Five community partners in California serving Latinx populations with high social vulnerability participated in the ¡Ándale! ¿Qué Esperas? campaign. Community health workers were hired to deliver outreach (virtual, one-on-one, group based, and information dissemination), vaccinations, and supportive services. We collected data on outreach strategy used (method and location), number of vaccinations provided and reasons for delay, and number of times that supportive services were provided. We used regression models to assess significant predictors of vaccinations and supportive services.
Results: Community health workers (N = 146) hired from June 1, 2021, through May 31, 2022, performed outreach engagements (n = 6297) and supportive services (n = 313 796), resulting in 130 413 vaccinations and 28 660 vaccine appointments. The number of vaccinations administered was significantly higher at events in which supportive services were provided versus not provided (coefficient = 34.02; 95% CI, 3.34-64.68; P = .03). The odds ratio of supportive services was 3.67 (95% CI, 1.76-7.55) during virtual outreach and 2.95 (95% CI, 2.37-3.69) during one-on-one outreach (P < .001 for both) as compared with information dissemination encounters. Vaccination concerns were reported among 55.0% of vaccinated survey respondents (67.7%, vaccine confidence; 51.7%, access).
Conclusions: Supportive services facilitate vaccinations, ease transportation and time barriers, and instill confidence among working-class racial and ethnic minority populations.
{"title":"Evaluation of the COVID-19 Vaccination Campaign <i>¡Ándale! ¿Qué Esperas?</i> in Latinx Communities in California, June 2021-May 2022.","authors":"Saira Nawaz, Kyle J Moon, Francis Anagbonu, Anne Trinh, Lizette Escobedo, Gloria Itzel Montiel","doi":"10.1177/00333549231204043","DOIUrl":"10.1177/00333549231204043","url":null,"abstract":"<p><strong>Objectives: </strong>The 12-month vaccination campaign <i>¡Ándale! ¿Qué Esperas?</i> was launched to increase COVID-19 vaccination rates in Latinx populations in California by expanding community outreach. The objectives of this evaluation were to (1) determine predictors of vaccination rates and (2) identify barriers to vaccination and potential solutions.</p><p><strong>Methods: </strong>Five community partners in California serving Latinx populations with high social vulnerability participated in the <i>¡Ándale! ¿Qué Esperas?</i> campaign. Community health workers were hired to deliver outreach (virtual, one-on-one, group based, and information dissemination), vaccinations, and supportive services. We collected data on outreach strategy used (method and location), number of vaccinations provided and reasons for delay, and number of times that supportive services were provided. We used regression models to assess significant predictors of vaccinations and supportive services.</p><p><strong>Results: </strong>Community health workers (N = 146) hired from June 1, 2021, through May 31, 2022, performed outreach engagements (n = 6297) and supportive services (n = 313 796), resulting in 130 413 vaccinations and 28 660 vaccine appointments. The number of vaccinations administered was significantly higher at events in which supportive services were provided versus not provided (coefficient = 34.02; 95% CI, 3.34-64.68; <i>P</i> = .03). The odds ratio of supportive services was 3.67 (95% CI, 1.76-7.55) during virtual outreach and 2.95 (95% CI, 2.37-3.69) during one-on-one outreach (<i>P</i> < .001 for both) as compared with information dissemination encounters. Vaccination concerns were reported among 55.0% of vaccinated survey respondents (67.7%, vaccine confidence; 51.7%, access).</p><p><strong>Conclusions: </strong>Supportive services facilitate vaccinations, ease transportation and time barriers, and instill confidence among working-class racial and ethnic minority populations.</p>","PeriodicalId":20793,"journal":{"name":"Public Health Reports","volume":" ","pages":"44S-52S"},"PeriodicalIF":3.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11339681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92156269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01Epub Date: 2024-02-12DOI: 10.1177/00333549231223923
Kirsten Wysen, Matías Valenzuela, Wendy E Barrington, Yordanos Teferi, Aselefech Evans, Bereket Kiros, Michelle Merriweather, Martha Zuniga
After a tumultuous 3 years of pandemic-, political-, and race-related unrest in the United States, the public is demanding accountability to communities of color (defined here as American Indian/Alaska Native, Asian, Black, Native Hawaiian/Pacific Islander, and Hispanic people) to rectify historic and contemporary injustices that perpetuate health inequities and threaten public health. Structural racism pervades all major societal systems and exposes people to detrimental social determinants of health. Disrupting structural racism within public health systems is essential to advancing health equity and requires organized partnerships between health departments and community leaders. As those who are most affected by structural racism, communities of color are the experts in knowing its impacts. This case study describes the King County Pandemic and Racism Community Advisory Group (PARCAG) and its use of an innovative accountability tool. The tool facilitated institutional transparency and accountability in the adoption of community recommendations. PARCAG was influential in shaping Public Health-Seattle & King County's COVID-19 and antiracism work, with 66 of 75 (88%) recommendations adopted partially or fully. For example, a fully adopted recommendation in May 2020 was to report King County COVID-19 case data by race and ethnicity, and a partially adopted recommendation was to translate COVID-19 information into additional languages. PARCAG members were recruited from a 2019 advisory board on Census 2020 and were adept at shifting to advising on COVID-19 and equitable practices and policies. Organizations that have made declarations that racism is a public health crisis should center the experiences, expertise, and leadership of communities of color in accountable ways when developing and implementing strategies to disrupt and repair the effects of structural racism and efforts to promote and protect public health.
{"title":"Public Health Accountability in Action: The King County Pandemic and Racism Community Advisory Group.","authors":"Kirsten Wysen, Matías Valenzuela, Wendy E Barrington, Yordanos Teferi, Aselefech Evans, Bereket Kiros, Michelle Merriweather, Martha Zuniga","doi":"10.1177/00333549231223923","DOIUrl":"10.1177/00333549231223923","url":null,"abstract":"<p><p>After a tumultuous 3 years of pandemic-, political-, and race-related unrest in the United States, the public is demanding accountability to communities of color (defined here as American Indian/Alaska Native, Asian, Black, Native Hawaiian/Pacific Islander, and Hispanic people) to rectify historic and contemporary injustices that perpetuate health inequities and threaten public health. Structural racism pervades all major societal systems and exposes people to detrimental social determinants of health. Disrupting structural racism within public health systems is essential to advancing health equity and requires organized partnerships between health departments and community leaders. As those who are most affected by structural racism, communities of color are the experts in knowing its impacts. This case study describes the King County Pandemic and Racism Community Advisory Group (PARCAG) and its use of an innovative accountability tool. The tool facilitated institutional transparency and accountability in the adoption of community recommendations. PARCAG was influential in shaping Public Health-Seattle & King County's COVID-19 and antiracism work, with 66 of 75 (88%) recommendations adopted partially or fully. For example, a fully adopted recommendation in May 2020 was to report King County COVID-19 case data by race and ethnicity, and a partially adopted recommendation was to translate COVID-19 information into additional languages. PARCAG members were recruited from a 2019 advisory board on Census 2020 and were adept at shifting to advising on COVID-19 and equitable practices and policies. Organizations that have made declarations that racism is a public health crisis should center the experiences, expertise, and leadership of communities of color in accountable ways when developing and implementing strategies to disrupt and repair the effects of structural racism and efforts to promote and protect public health.</p>","PeriodicalId":20793,"journal":{"name":"Public Health Reports","volume":" ","pages":"30S-36S"},"PeriodicalIF":3.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11339679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139723776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}