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Laboratory test results and computed tomography findings in health care professionals with COVID-19. COVID-19卫生保健专业人员的实验室检测结果和计算机断层扫描结果。
Q3 Medicine Pub Date : 2026-01-02 eCollection Date: 2025-01-01 DOI: 10.1590/0100-3984.2025.0036-en
Danilo Alves de Araujo, Igor Duarte Pinto Paciello, Samuel Herdy Figueira, Victor Teixeira Ramos Lopes, João Pedro Coelho de Oliveira Barros, Lucas Vazquez Barreira Ranzeiro de Bragança, Matheus Rodrigues Miranda, Alair Augusto Sarmet Moreira Damas Dos Santos

Objective: To assess the intensity, characteristics, and distribution of computed tomography (CT) findings of pulmonary involvement, as well as to evaluate laboratory test results, in health care professionals who were exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Materials and methods: This was a retrospective, cross-sectional, observational study based on the analysis of laboratory test results and chest CT images of health care workers with confirmed coronavirus disease 2019 (COVID-19). Data for the period from March 2020 to December 2022 were collected from two hospitals in Brazil.

Results: We identified 1,091 health care professionals in whom a RT-PCR was positive for SARS-CoV-2. However, only 38 of those individuals underwent chest CT. Of the 38 individuals evaluated, 89.5% were treated at one of the hospitals and 57.9% were male. The mean age was 55.6 years. The most common finding (in 100% of the cases) was ground-glass opacity, followed by septal thickening (in 31.6%) and consolidation (in 23.7%). Pulmonary involvement was multifocal in 76.3% and predominantly subpleural in 71.0%. The extent of the involvement was classified as mild in 24% of the cases, moderate in 47%, and severe in 29%. The most commonly affected lung region (in 60.7% of cases) was the lower lobes, particularly the right posterior basal segmental bronchus (segment B10).

Conclusion: For evaluating lung involvement, CT was essential, aiding in postinfection monitoring and in the early management of complications. Among the health care professionals evaluated, moderate involvement predominated.

目的:评估暴露于严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)的卫生保健专业人员肺部受累的计算机断层扫描(CT)表现的强度、特征和分布,并评估实验室检查结果。材料与方法:本研究是一项回顾性、横断面、观察性研究,基于对确诊的2019冠状病毒病(COVID-19)医护人员的实验室检查结果和胸部CT图像的分析。2020年3月至2022年12月期间的数据从巴西的两家医院收集。结果:我们确定了1091名卫生保健专业人员,其中RT-PCR对SARS-CoV-2呈阳性。然而,其中只有38人接受了胸部CT检查。在接受评估的38名个体中,89.5%在其中一家医院接受治疗,57.9%为男性。平均年龄为55.6岁。最常见的表现(100%)是磨玻璃样混浊,其次是间隔增厚(31.6%)和实变(23.7%)。76.3%的肺部受累是多灶性的,71.0%主要是胸膜下受累。24%的病例受累程度为轻度,47%为中度,29%为重度。最常受影响的肺区(60.7%)为肺下叶,尤其是右侧后基支气管(B10段)。结论:在评估肺部受累时,CT是必不可少的,有助于感染后监测和并发症的早期处理。在被评估的卫生保健专业人员中,中度参与占主导地位。
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引用次数: 0
Axillary evaluation in women with elevated body mass index: evidence, challenges, and perspectives. 体重指数升高的女性腋窝评估:证据、挑战和观点。
Q3 Medicine Pub Date : 2025-12-22 eCollection Date: 2025-01-01 DOI: 10.1590/0100-3984.2025.58.e11
Renato Leme de Moura Ribeiro, Erica Elisangela Françolin Federicci
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引用次数: 0
Next steps for transrectal ultrasound-guided prostate biopsy - where microvascular flow imaging plays a role. 下一步是经直肠超声引导的前列腺活检,其中微血管血流成像起作用。
Q3 Medicine Pub Date : 2025-12-22 eCollection Date: 2025-01-01 DOI: 10.1590/0100-3984.2025.58.e10
Andrea Cavalanti Gomes, Rodrigo Salvador Vivas Cardoso
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引用次数: 0
Refining the assessment of BI-RADS 4 lesions on breast magnetic resonance imaging. 改进乳腺磁共振成像BI-RADS 4病变的评估。
Q3 Medicine Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1590/0100-3984.2025.0035-en
Luciana Graziano, Bianca Miranda Lago, Camila Souza Guatelli, Juliana Alves, Mariah Carneiro Wanderley, Vinicius Cardona Felipe, Almir Galvão Vieira Bitencourt

Objective: To evaluate the positive predictive value (PPV) of the imaging characteristics of breast lesions classified as BI-RADS category 4 (risk of malignancy > 2% to < 95%) on magnetic resonance imaging (MRI), in order to create an algorithm to subcategorize such lesions.

Materials and methods: This was a retrospective study including 199 breast lesions (131 nodules and 68 non-mass lesions) classified as BI-RADS 4 on MRI. Of the 199 lesions, 93 were excluded, for various reasons: they were lymph nodes; they were not biopsied or were not followed at our center; they were additional findings in patients with an established diagnosis of malignancy who underwent mastectomy without further investigation; or they were identified in examinations that were not recovered from the digital archive. Multivariate analysis was performed to identify the most relevant descriptors to predict malignancy and to build an algorithm to subcategorize lesions into BI-RADS 4A, 4B, and 4C. Four breast radiologists then tested the algorithm in another 95 patients with breast lesions classified as BI-RADS 4 on MRI, 27 (28.4%) of those lesions having previously been classified as malignant.

Results: The descriptors statistically associated with malignancy in the multivariate analysis of the nodules were background parenchymal enhancement, margins, and the initial phase of the kinetic curve. An algorithm was developed by using these resources, and the PPV obtained for each category was 4.3% for BI-RADS 4A, 21.4% for BI-RADS 4B, and 78.9% for BI-RADS 4C. In the validation of the algorithm by the four breast radiologists, the PPV of the subcategories was within the BI-RADS malignancy ranges in almost all situations, the exceptions being the 11.1% that one evaluator obtained for category 4A and the 46.4% obtained for category 4C by another evaluator.

Conclusion: The objective analysis employing the proposed algorithm proved useful for subdividing BI-RADS 4 mass lesions on MRI and showed better interobserver agreement than did the subjective analysis.

目的:评价BI-RADS第4类乳腺病变(恶性风险> % ~ < 95%)在磁共振成像(MRI)上的影像特征阳性预测值(PPV),以建立对该类病变亚分类的算法。材料和方法:这是一项回顾性研究,包括199个乳腺病变(131个结节和68个非肿块性病变)在MRI上被分类为BI-RADS 4。199个病变中,93个因各种原因被排除在外:它们是淋巴结;他们没有在我们的中心接受活检或随访;在确诊为恶性肿瘤的患者中,在没有进一步调查的情况下进行了乳房切除术;或者是在没有从数字档案中恢复的检查中发现的。进行多变量分析以确定预测恶性肿瘤的最相关描述符,并建立将病变亚分类为BI-RADS 4A, 4B和4C的算法。然后,四名乳腺放射科医生在另外95名乳房病变在MRI上被分类为BI-RADS 4的患者中测试了该算法,其中27例(28.4%)病变先前被分类为恶性。结果:在多变量分析中,与结节恶性相关的描述词是背景实质增强、边缘和动力学曲线的初始阶段。利用这些资源开发了一种算法,BI-RADS 4A、BI-RADS 4B和BI-RADS 4C的PPV分别为4.3%、21.4%和78.9%。在四位乳腺放射科医生对算法的验证中,几乎所有情况下,子类别的PPV都在BI-RADS恶性范围内,除了一位评估者对4A类获得的11.1%和另一位评估者对4C类获得的46.4%。结论:采用所提出的算法进行客观分析,可在MRI上对BI-RADS 4肿块病变进行细分,且观察者间的一致性优于主观分析。
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引用次数: 0
Pituitary macroadenoma: less common neuroimaging features in a common lesion. 垂体大腺瘤:常见病变中少见的神经影像学特征。
Q3 Medicine Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1590/0100-3984.2025.0065
Fernanda Veloso Pereira, Natália Yaktine Yoshida, Davi Ferreira Soares, Heraldo Mendes Garmes, Denise Engelbrecht Zantut-Wittmann, Fábio Rogério, Mateus Dal Fabbro, Juliana Ávila Duarte, Fabiano Reis

Pituitary neuroendocrine tumors, previously known as pituitary adenomas, are the most common pituitary gland tumors; when larger than 10 mm in diameter, they are called pituitary macroadenomas. Although most pituitary macroadenomas exhibit characteristic imaging features, some present with uncommon neuroimaging manifestations. Less common imaging manifestations include hemorrhage, areas of necrosis, cystic components, calcifications, bone invasion, and extrasellar location. Knowing how to recognize the atypical neuroimaging patterns of pituitary macroadenomas is also crucial for identifying the potential aggressive behavior of the lesion. In addition to predicting aggressive behavior, recognition of atypical neuroimaging characteristics can help the neurosurgeon determine the most effective surgical approach. The aim of this review was to highlight the less common imaging patterns of pituitary macroadenomas.

垂体神经内分泌肿瘤,以前称为垂体腺瘤,是最常见的垂体肿瘤;当直径大于10mm时,称为垂体大腺瘤。虽然大多数垂体大腺瘤表现出特征性的影像学特征,但也有一些表现出不常见的神经影像学表现。较不常见的影像学表现包括出血、坏死区、囊性成分、钙化、骨侵犯和鞍外定位。了解如何识别垂体大腺瘤的非典型神经影像学模式对于识别病变的潜在侵袭行为也至关重要。除了预测攻击行为外,识别非典型神经影像学特征可以帮助神经外科医生确定最有效的手术方法。本综述的目的是强调垂体大腺瘤不常见的影像模式。
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引用次数: 0
Real-life diagnostic performance of opportunistic computed tomography screening for osteoporosis in Brazilian adults: a retrospective validation study. 巴西成人骨质疏松症的机会性计算机断层扫描的真实诊断性能:一项回顾性验证研究。
Q3 Medicine Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1590/0100-3984.2025.0073
Fabio Brandão Yoshimura, Írline Cordeiro de Macedo Pontes, Erina Megumi Nagaya Fukamizu, Eduardo Kaiser Ururahy Fonseca, Patricia Yokoo, Akemi Osawa, Adham do Amaral E Castro

Objective: To evaluate the diagnostic accuracy of computed tomography (CT) for detecting osteoporosis in Brazilian adults, using dual-energy X-ray absorptiometry (DXA) as the reference standard.

Materials and methods: We conducted a retrospective analysis of adults over 50 years of age who underwent CT (chest, abdominal, or lumbar scans) and DXA within a 60-day interval, between January 2012 and December 2022. Vertebral bone attenuation at L1 was quantified in Hounsfield units. Thresholds of > 160 HU and < 100 HU were used in order to classify bone as normal and osteoporotic, respectively. Two musculoskeletal radiologists, working independently, performed subjective classifications. Sensitivity, specificity, predictive values, and interobserver agreement (Cohen's kappa) were calculated. The influence of contrast use and scanner heterogeneity was considered.

Results: Ninety-five patients met the inclusion criteria. On the basis of the DXA results, we identified 39 normal cases, 46 cases of osteopenia, and 10 cases of osteoporosis. For detecting normal bone, objective CT measurements demonstrated a sensitivity of 88.6% and a specificity of 95.5%. For detecting osteoporosis, the sensitivity was 75.3% and the specificity was 99.7%. For the subjective classification, the level of interobserver agreement was fair (κappa = 0.384). The study included CT scans from different scanner models, with and without contrast enhancement.

Conclusion: Opportunistic CT demonstrated high specificity but only moderate sensitivity for osteoporosis detection. The attenuation thresholds previously validated in populations elsewhere show promise for use in Brazil. However, scanner variability, contrast use, and limited sample size constrain generalizability. Larger, multicenter prospective studies are warranted.

目的:以双能x线骨密度仪(DXA)为参考标准,评价CT对巴西成人骨质疏松症的诊断准确性。材料和方法:我们对2012年1月至2022年12月间60天内接受CT(胸部、腹部或腰部扫描)和DXA检查的50岁以上成年人进行了回顾性分析。L1处椎体骨衰减以Hounsfield单位量化。将骨分为正常和骨质疏松的阈值分别为bb0 ~ 160 HU和< 100 HU。两名独立工作的肌肉骨骼放射科医生进行了主观分类。计算敏感性、特异性、预测值和观察者间一致性(Cohen’s kappa)。考虑了造影剂使用和扫描仪异质性的影响。结果:95例患者符合纳入标准。根据DXA结果,我们确定了39例正常病例,46例骨质减少,10例骨质疏松症。对于检测正常骨,客观CT测量显示敏感性为88.6%,特异性为95.5%。检测骨质疏松的灵敏度为75.3%,特异性为99.7%。主观分类方面,观察者间认同水平尚可(κappa = 0.384)。该研究包括不同扫描仪型号的CT扫描,有增强和没有增强。结论:机会性CT对骨质疏松症的检测特异性高,敏感性中等。先前在其他地方人群中验证的衰减阈值显示出在巴西使用的希望。然而,扫描仪的可变性、对比度的使用和有限的样本量限制了普遍性。更大的、多中心的前瞻性研究是必要的。
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引用次数: 0
State of the art of PET/MRI for rectal cancer: the added value to conventional imaging. PET/MRI在直肠癌诊断中的应用现状:传统影像学的附加价值。
Q3 Medicine Pub Date : 2025-12-08 eCollection Date: 2025-01-01 DOI: 10.1590/0100-3984.2025.0060
Poliana Fonseca Zampieri, Daniel Barros Garcia Hernandes, David Alberto Gutiérrez Albenda, Natally Horvat, Onofrio Antonio Catalano, Carlos Alberto Buchpiguel, Marcelo Araújo Queiroz

Imaging plays a critical role in the assessment of patients with rectal cancer, and positron emission tomography/magnetic resonance imaging (PET/MRI) has shown superiority in specific clinical scenarios. This review describes the potential contribution of 18F-fluorodeoxyglucose (18F-FDG) PET/MRI relative to standard of care imaging-computed tomography (CT), MRI, or PET/CT-in the evaluation of patients with rectal cancer in settings such as primary staging, treatment response assessment, and recurrence detection. We discuss 18F-FDG PET/MRI protocols and clinical workflow, as well as highlighting the potential clinical superiority of PET/MRI over other imaging modalities.

影像学在直肠癌患者的评估中起着至关重要的作用,正电子发射断层扫描/磁共振成像(PET/MRI)在特定的临床情况下显示出优势。本综述描述了18f -氟脱氧葡萄糖(18F-FDG) PET/MRI相对于标准护理成像——计算机断层扫描(CT)、MRI或PET/CT——在评估直肠癌患者的初始分期、治疗反应评估和复发检测等方面的潜在贡献。我们讨论了18F-FDG PET/MRI方案和临床工作流程,并强调了PET/MRI相对于其他成像方式的潜在临床优势。
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引用次数: 0
Multimodal imaging of apophyseal avulsion fractures in adolescent soccer players: contributions of plain radiography, power Doppler, and magnetic resonance imaging. 青少年足球运动员棘突撕脱骨折的多模态成像:平片、功率多普勒和磁共振成像的贡献。
Q3 Medicine Pub Date : 2025-12-08 eCollection Date: 2025-01-01 DOI: 10.1590/0100-3984.2025.0059
Roberto Mogami, Claudio Henrique Ivo de Araújo Ribeiro Filho, Eduardo Brown Guedes Dos Santos, André de Almeida Vieira, Lucas Nascimento da Luz, Caio Leal Leidersnaider, Natália Fernandes de Azevedo, Edson Marchiori, Paulo Sérgio Chagas Gomes

Objective: To evaluate, primarily, the accuracy of plain radiography (X-ray) in diagnosing apophyseal avulsion fractures in adolescent soccer players, using magnetic resonance imaging (MRI) as the gold standard. As secondary objectives, we investigated associations between findings on X-ray, MRI, and power Doppler, as well as the imaging features that distinguish avulsion fractures from apophysitis.

Materials and methods: This was an observational cross-sectional study involving 33 male athletes 9-17 years of age with clinical suspicion of an apophyseal avulsion fracture. Imaging examinations were performed within the first 24 h after the trauma. We evaluated diagnostic reproducibility among readers, the accuracy of X-ray compared with MRI, and the associations between findings from different imaging methods.

Results: We found that X-ray had an accuracy of 56.0%, with high specificity (71.4%) and positive predictive value (81.8%), although its sensitivity and negative predictive value were relatively low (50.0% and 35.7%, respectively). The power Doppler result was significantly associated with avulsion fractures detected on MRI (p = 0.0144). Avulsion fractures were associated with periphyseal edema and intermuscular fluid collections, while apophysitis was associated with bone marrow edema.

Conclusion: X-ray is useful for confirming, but not for excluding, avulsion fractures. Power Doppler and MRI contribute to the differential diagnosis.

目的:以磁共振成像(MRI)为金标准,初步评价x线平片(x线平片)诊断青少年足球运动员棘突撕脱骨折的准确性。作为次要目的,我们研究了x线、MRI和功率多普勒检查结果之间的关系,以及区分撕脱性骨折和骨突炎的影像学特征。材料和方法:这是一项观察性横断面研究,涉及33名9-17岁的男性运动员,临床怀疑为棘突撕脱骨折。创伤后24小时内进行影像学检查。我们评估了读者诊断的可重复性,x射线与MRI的准确性,以及不同成像方法结果之间的相关性。结果:x线诊断准确率为56.0%,特异度为71.4%,阳性预测值为81.8%,敏感性和阴性预测值较低(分别为50.0%和35.7%)。功率多普勒结果与MRI上发现的撕脱骨折有显著相关性(p = 0.0144)。撕脱性骨折与骨骺周围水肿和肌间积液有关,而骨骺炎与骨髓水肿有关。结论:x线对撕脱性骨折的诊断有一定的帮助,但不能排除。功率多普勒和MRI有助于鉴别诊断。
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引用次数: 0
Efficacy of pelvic-abdominal shields in radiation protection of patients undergoing radial coronary angiography: experimental analysis and recommendations for radiology practice. 盆腹护罩对桡动脉冠状动脉造影患者的辐射防护效果:实验分析及放射学实践建议。
Q3 Medicine Pub Date : 2025-12-08 eCollection Date: 2025-01-01 DOI: 10.1590/0100-3984.2025.0040-en
Luciana Aparecida Salgado Rodrigues, Letícia Lucente de Campos Rodrigues, João Ricardo Antunes Marcos, Desidério Favarato, Maria de Fátima de Andrade Magon, Isabel Alves de Barros Morales, Erlon Oliveira de Abreu-Silva, George César Ximenes Meireles

Objective: To develop and evaluate the use of radiation shields for patients undergoing coronary angiography via the radial approach.

Materials and methods: Two pelvic-abdominal shields were developed-one for the posterior region and one for the anterior region. To analyze the entrance dose and its attenuation through the patient until reaching a detector as residual radiation, two dosimeter strips (right and left) were created and inserted into a phantom.

Results: Comparing the shielded and unshielded groups, we found that the radiation doses at all detector positions were significantly higher in the shielded group (p < 0.0001).

Conclusion: The use of pelvic-abdominal radiation shields made with 0.5 mm of lead is not recommended for patients undergoing interventional cardiology procedures, because it significantly increases radiation exposure and therefore does not comply with the As Low as Reasonably Achievable principle.

目的:探讨放射防护在经桡动脉入路冠状动脉造影中的应用。材料和方法:制备了两个骨盆-腹膜,一个用于后区,一个用于前区。为了分析进入剂量及其在病人体内的衰减,直到作为残余辐射到达检测器,制作了两条剂量计条(右和左)并插入到一个幻影中。结果:与未屏蔽组比较,屏蔽组各探测器位置的辐射剂量均显著高于未屏蔽组(p < 0.0001)。结论:不推荐在心脏介入手术患者中使用0.5 mm铅制成的盆腹辐射屏蔽,因为它会显著增加辐射暴露,因此不符合As Low As reasonable possible原则。
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引用次数: 0
State of the art of PET/MRI for rectal cancer assessment. PET/MRI用于直肠癌评估的最新进展。
Q3 Medicine Pub Date : 2025-12-08 eCollection Date: 2025-01-01 DOI: 10.1590/0100-3984.2025.58.e8-en
Caroline Lorenzoni Almeida Ghezzi, Aline Spader Casagrande, Tiago Leal Ghezzi
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引用次数: 0
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Radiologia Brasileira
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