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Effects of different water activities on the stability of carotenoids in puff-dried yellow peach powder during storage 不同水分活度对黄桃泡干粉贮存过程中类胡萝卜素稳定性的影响
IF 4 3区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-09-23 DOI: 10.15586/qas.v13sp2.944
Gorby Gonzalles, Ningning Geng, Shuwei Luo, Chenchen Zhang, Cai-E. Wu, Dajing Li, Ying Li, Jiangfeng Song
The stability of carotenoids in puff-dried yellow peach powder during commercial storage under different water activity conditions was studied. The results showed that when the corresponding water activity was above 0.576, the loss of adsorbed water in yellow peach powder was closely related to the crystallinity of the amorphous sugar matrix. However, the adsorption isotherms confirmed by water absorption behavior, X-ray diffraction (XRD) pat-terns, and scanning electron microscopy did not clearly indicate this loss of adsorbed water. The content changes of individual carotenoids (lutein, zeaxanthin, β-cryptoxanthin, α-carotene, and β-carotene) during storage followed pseudo first-order kinetics, and the degradation of lutein and zeaxanthin occurred quickly over time. The stability of total carotenoids gradually increased when the water activity was less than 0.576, but the carotenoids degraded sharply when the water activity was between 0.753 and 0.843. The loss of carotenoids was related to the water absorption and crystallization of the sugar matrix in the powder.
研究了膨化黄桃粉在不同水分活度条件下商品化贮藏过程中类胡萝卜素的稳定性。结果表明,当相应的水分活度高于0.576时,黄桃粉中吸附水分的损失与无定形糖基质的结晶度密切相关。然而,通过吸水行为、X射线衍射(XRD)图谱和扫描电子显微镜证实的吸附等温线并没有清楚地表明吸附水的这种损失。单个类胡萝卜素(叶黄素、玉米黄质、β-隐黄质、α-胡萝卜素和β-胡萝卜素)在储存过程中的含量变化遵循伪一级动力学,随着时间的推移,叶黄素和玉米黄质的降解速度很快。当水活度小于0.576时,总类胡萝卜素的稳定性逐渐增加,但当水活度在0.753至0.843之间时,类胡萝卜素急剧降解。类胡萝卜素的损失与粉末中糖基质的吸水性和结晶性有关。
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引用次数: 1
Antimicrobial potential of kombucha against foodborne pathogens 康普茶对食源性病原体的抗菌潜力
IF 4 3区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-08-30 DOI: 10.15586/qas.v13i3.920
J. Hou, Rongyao Luo, Hui Ni, Ke Li, Fedrick C. Mgomi, Luyao Fan, Lei Yuan
The survival of foodborne pathogens under stressful food processing conditions and in host’s gastrointestinal tract has been widely reported to cause the outbreak of human diseases. Generally, antibiotics have been used to elimi-nate the microbial flora of foodborne pathogens. However, the overuse of antibiotics has contributed to the emergence and spread of multi-drug-resistant foodborne pathogens. Kombucha is a beverage prepared by fermenting sugared tea or other substrates with a symbiotic culture of yeasts and bacteria, and has been proved to fight food-borne pathogens and affect gastrointestinal microbial flora to prevent foodborne illnesses. In this context, this review primarily focused on microbiological and chemical compositions of kombucha obtained by fermenting different substrates. It further discussed the antimicrobial activity of kombucha, as well as potential antimicrobial agents found in kombucha, and the limitations of kombucha in the food industry. In addition, the need for developing antimicrobial agents from kombucha has been discussed for potential applications. The information provided in this review indicates that kombucha could serve as an alternative approach to control pathogens in place of using antibiotics.
食源性病原体在紧张的食品加工条件下和宿主胃肠道中的存活已被广泛报道为导致人类疾病爆发的原因。一般来说,抗生素已被用于消灭食源性病原体的微生物群。然而,抗生素的过度使用导致了耐多药食源性病原体的出现和传播。康普茶是一种通过酵母和细菌的共生培养物发酵加糖茶或其他基质制备的饮料,已被证明可以对抗食源性病原体,并影响胃肠道微生物菌群,预防食源性疾病。在此背景下,本文主要综述了通过发酵不同底物获得的康普茶的微生物和化学成分。它进一步讨论了康普茶的抗菌活性,以及在康普茶中发现的潜在抗菌剂,以及康普茶在食品工业中的局限性。此外,还讨论了从康普茶中开发抗菌剂的潜在应用需求。这篇综述中提供的信息表明,康普茶可以作为控制病原体的替代方法,而不是使用抗生素。
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引用次数: 13
Isolation and characterization of broad host-range of bacteriophages infecting Cronobacter sakazakii and its biocontrol potential in dairy products 广宿主范围阪崎克罗诺杆菌噬菌体的分离、鉴定及其在乳制品中的生物防治潜力
IF 4 3区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-08-06 DOI: 10.15586/qas.v13i3.890
Li Huaxiang, Yang Xiaojun, Xiao-yan Zhu, Lu Gao, Sheng-qi Rao, Lei Yuan, Zhen-quan Yang
Cronobacter sakazakii (C. sakazakii) is an important pathogen contaminating dairy products (e.g., milk pow-der) and causes high mortality in infants. Bacteriophage as a potential biocontrol agent is a good alternative method for the control of this pathogen in dairy production and its environment. Thus, it is important to complete the C. sakazakii phage library by isolating and characterizing the broad host range of bacteriophage against C. sakazakii for control use. In this study, C. sakazakii strains from different sources were used as hosts to isolate and purify phages from human stool and sewage samples by double-layer plates. The biological characteristics, antibacterial properties, and genomes of these phages were then studied. Finally, ten virulent phages (EspYZU01–EspYZU10) infecting C. sakazakii were isolated and identified as belonging to the Myoviridae, Podoviridae, Tectivirus, and Stylovinidae families. Phage EspYZU08 presented the broadest host range and could infect all the five host strains of C. sakazakii. All 10 phages retained their infectivity at 50°C and pH 5–9. Both genomes of EspYZU05 and EspYZU08 were double-stranded DNAs with sizes of 41723 bp and 145582 bp, G+C contents of 55.69% and 46.75%, and open reading frames of 47 and 103, respectively. No toxins and antibiotic resistance genes were detected in both EspYZU05 and EspYZU08. Phage EspYZU08 and phage cocktail-3 (EspYZU01 + EspYZU03 + EspYZU08 + EspYZU09 + EspYZU10) presented excellent antibacterial efficacy for C. sakazakii in liquid broth and milk at 4°C, 25°C, and 37°C, suggesting that the phages in this study have great potential for the development of biocontrol agents against C. sakazakii in dairy and its processing environment.
阪崎克罗诺杆菌(C.sakazakii)是一种污染乳制品(如奶粉)的重要病原体,可导致婴儿高死亡率。噬菌体作为一种潜在的生物防治剂,是控制乳制品生产及其环境中这种病原体的一种很好的替代方法。因此,重要的是通过分离和表征针对阪崎肠杆菌的广泛宿主范围的噬菌体来完成阪崎大肠杆菌噬菌体文库,以供对照使用。本研究以不同来源的阪崎肠杆菌菌株为宿主,采用双层平板法从人类粪便和污水样品中分离纯化噬菌体。然后对这些噬菌体的生物学特性、抗菌特性和基因组进行了研究。最后,分离出10个感染阪崎肠杆菌的毒力噬菌体(EspYZU01–EspYZU10),并鉴定为属于Myoviride、Podoviridae、Tectivirus和Styloviride科。EspYZU08噬菌体的寄主范围最广,可感染阪崎肠杆菌的5个寄主菌株。所有10个噬菌体在50°C和pH 5-9时都保持了感染性。EspYZU05和EspYZU_8的基因组均为双链DNA,大小分别为41723bp和145582bp,G+C含量分别为55.69%和46.75%,开放阅读框分别为47和103。在EspYZU05和EspYZU18中均未检测到毒素和抗生素抗性基因。在4°C、25°C和37°C的液体肉汤和牛奶中,噬菌体EspYZU08和噬菌体cocktail-3(EspYZU11+EspYZU23+EspYZU48+EspYZU9+EspYZU10)对阪崎肠杆菌表现出优异的抗菌效果,表明本研究中的噬菌体在开发乳制品及其加工环境中的阪崎大肠杆菌生物防治剂方面具有巨大的潜力。
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引用次数: 11
Optimization method of microwave drying process parameters for rice 大米微波干燥工艺参数的优化方法
IF 4 3区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-07-28 DOI: 10.15586/qas.v13i3.917
T. Sun, Fan Ling
In this work, the optimal process to improve the efficiency of microwave drying of rice is studied. The optimal conditions for reducing the crack rate and improving the head rice rate are analyzed according to the principle of the orthogonal experiment. The optimization method of the rice microwave drying process parameters is proposed to simultaneously consider the two indicators, namely, crack and head rice rates, based on the grey system theory. The grey correlation degree analysis is carried out on the process conditions of the microwave drying rice. The result shows that the main factor affecting the integrity rate of the rice grain is the vacuum degree, and the main factor affecting the crack rate is the loading density. The grey correlation degree curve of head rice and crack rate fluctuates greatly, and the correlation between the two indexes is high. According to the grey correlation degree, the optimal parameters are microwave power of 500 W, vacuum degree of 0.02 MPa, and loading density of 1289.89 kg/m3. The head rice and crack rate are both optimized when drying under the parameters. The results provide a guiding method for the study of the correlation degree between drying indexes and provide a method basis for the further selection of the best drying process.
本文研究了提高大米微波干燥效率的最佳工艺。根据正交试验原理,分析了降低裂纹率和提高精米率的最佳条件。基于灰色系统理论,提出了同时考虑裂米率和整米率两个指标的大米微波干燥工艺参数优化方法。对微波干燥大米的工艺条件进行了灰色关联度分析。结果表明,影响米粒完整率的主要因素是真空度,而影响裂纹率的主要因子是加载密度。整精米与裂率的灰色关联度曲线波动较大,两个指标之间的相关性较高。根据灰色关联度,最佳参数为微波功率500W,真空度0.02MPa,负载密度1289.89kg/m3。在一定的干燥参数下,稻谷的精米率和干裂率都得到了优化。研究结果为研究干燥指标之间的相关性提供了指导方法,为进一步选择最佳干燥工艺提供了方法依据。
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引用次数: 4
Effect of different sterilization methods on sensory quality and volatile flavor of flavor crab meat sauce 不同杀菌方法对风味蟹肉酱感官品质及挥发性风味的影响
IF 4 3区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-07-05 DOI: 10.15586/QAS.V13I3.896
Yajun Zhu, Haoran Wu, Futian Wang, Shaotong Jiang, Lin Lin, Jianfeng Lu
Flavor crab meat sauce (FCMS) is a new type of aquatic condiment that is not only rich in nutrition but also unique in terms of flavor. However, very little is known about how sterilization methods affect the sensory quality and volatile flavor of FCMS. In the present study, canned FCMS was subjected to the following sterilization methods: pasteurization (PS), microwave sterilization (MS), ultrasonic sterilization (US), and high temperature sterilization (HTS). Each sterilization method was evaluated on the basis of texture, color, sensory score, volatile flavor, and total viable counts in FCMS observed after sterilization. Results demonstrated that the total viable count decreased to 28, 26, 58, and 18 CFU/g respectively after PS, MS, US, and HTS treatments; no coliform group was detected in any of these samples. PS and MS had no significant effect on the texture of FCMS (P > 0.05), but US and HTS reduced hardness and viscosity of FCMS. MS and HTS significantly reduced the L*, a*, and b* values of FCMS (P < 0.05). The original brightness and red value of FCMS remained the same after PS and US. MS and HTS reduced the sensory score of FCMS to a great extent, while PS and US maintained the original sensory score of FCMS. Assessment of volatile flavor profile of FCMS post different sterilization treatments revealed that MS and HTS reduced the total ester content, while US reduced the total amount of alcohols in FCMS. However, PS not only maintained the original total amount of esters in FCMS, but also increased the content of alcohols, aldehydes, and ketones. Therefore, PS could be selected as a feasible sterilization method for FCMS among the four different sterilization methods.
风味蟹肉酱是一种营养丰富、风味独特的新型水产调味品。然而,人们对杀菌方法如何影响FCMS的感官质量和挥发性风味知之甚少。在本研究中,罐装FCMS采用以下杀菌方法:巴氏杀菌(PS)、微波杀菌(MS)、超声波杀菌(US)和高温杀菌(HTS)。根据灭菌后观察到的FCMS中的质地、颜色、感官评分、挥发性风味和总活菌数对每种灭菌方法进行评估。结果表明,PS、MS、US和HTS处理后,总活菌数分别降至28、26、58和18CFU/g;在这些样品中均未检测到大肠菌群。PS和MS对FCMS的织构没有显著影响(P>0.05),但US和HTS降低了FCMS的硬度和粘度。MS和HTS显著降低了FCMS的L*、a*和b*值(P<0.05)。PS和US后FCMS的原始亮度和红色值保持不变。MS和HTS在很大程度上降低了FCMS的感官评分,而PS和US保持了FCMS原始的感官评分。对不同灭菌处理后FCMS的挥发性风味特征的评估表明,MS和HTS降低了FCMS中的总酯含量,而US降低了FCMS中的醇总量。然而,PS不仅保持了FCMS中酯的原始总量,而且增加了醇、醛和酮的含量。因此,在四种不同的杀菌方法中,PS可以被选为FCMS的一种可行的杀菌方法。
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引用次数: 4
Prevalence, determination, and control of histamine formation in food concerning food safety aspect 与食品安全相关的食品中组胺形成的流行率、测定和控制
IF 4 3区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-06-11 DOI: 10.15586/QAS.V13I2.886
C. Hoang, T. Nguyen, T. Le
Histamine is a toxic metabolite produced in foods containing a high level of free histidine. This compound can be present in various food sources, especially seafood, dairy products, and fermented foods. Histamine poisoning is one of the most common health risks caused by consuming spoiled foods or improper processed and stored foods. This food poisoning usually causes mild symptoms with higher recovery rates, so people underestimate this hazard. Thus, understanding histamine formation food sources with a high risk for this poisonous agent is critical in improving the awareness of this hazard for food producers and consumers. To avoid histamine-associated food poisoning, the development of control solutions to minimize the formation of histamine and the sufficient detection methods to examine the content of this metabolite in food products are vital. In addition to quality control application and hazards management programs in food processing, the appropriate food regulations identifying the precise limit of histamine in foods are essential for preventing this poisoning from occurring in the food supply chain. This review discusses the prevalence, control strategies, detection techniques, and regulations related to histamine hazards in foods.
组氨酸是一种有毒的代谢产物,在含有高水平游离组氨酸的食物中产生。这种化合物可以存在于各种食物来源中,尤其是海鲜、乳制品和发酵食品。组胺中毒是由食用变质食品或不当加工和储存的食品引起的最常见的健康风险之一。这种食物中毒通常会导致症状轻微,恢复率较高,因此人们低估了这种危害。因此,了解组胺形成的食物来源对这种有毒物质的高风险,对于提高食品生产商和消费者对这种危险的认识至关重要。为了避免组胺相关的食物中毒,开发控制溶液以最大限度地减少组胺的形成,并制定足够的检测方法来检测食品中这种代谢物的含量,这一点至关重要。除了食品加工中的质量控制应用和危害管理程序外,确定食品中组胺精确限量的适当食品法规对于防止这种中毒在食品供应链中发生至关重要。这篇综述讨论了食品中组胺危害的流行率、控制策略、检测技术和相关法规。
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引用次数: 6
Antioxidant and antibacterial activity of ethanolic extract of safflower with contrasting seed coat colors 种皮颜色对比红花乙醇提取物的抗氧化和抗菌活性
IF 4 3区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-06-02 DOI: 10.15586/QAS.V13I2.866
Basaki Tayebeh, Karami Soraya, A. Khaneghah
The present study aimed to investigate total flavonoid (TFC), cyanidin-3-glucoside (Cyd-3-glu) content, and antioxidant and antibacterial activities of ethanolic seed coat extract of two safflower genotypes (genotype C111 and A82) with contrasting seed coat colors. Despite the absence of Cyd-3-glu in seed coat extracts of white-seeded genotype C111 versus black-seeded genotype A82 and equal TFC index between the two genotypes, there was no significant difference in their antioxidant activity. Also, the ethanolic extract has growth inhibitory properties in pathogenic bacteria. It seems that differences in type and level of secondary metabolites of the seed coat with different color patterns can result in the ethanolic extract’s antioxidant activity. In addition, the results confirmed that seed coat color has not effect on the level (or severity) of the antibacterial properties of ethanolic seed coat extract.
本研究旨在研究两种不同种皮颜色基因型(C111和A82)红花种皮乙醇提取物的总黄酮(TFC)、花青素-3-葡萄糖苷(Cyd-3-glu)含量及其抗氧化和抗菌活性。白籽C111和黑籽A82种皮提取物中不含Cyd-3-glu, TFC指数相同,但抗氧化活性差异不显著。此外,乙醇提取物对致病菌具有生长抑制作用。不同花色种皮次生代谢物的类型和水平的差异可能是影响乙醇提取物抗氧化活性的主要原因。此外,实验结果证实种皮颜色对乙醇种皮提取物的抑菌性能没有影响。
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引用次数: 5
Industrial and culinary practice effects on biologically active polyamines level in turkey meat 工业和烹饪实践对火鸡肉中生物活性多胺水平的影响
IF 4 3区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-05-26 DOI: 10.15586/QAS.V13I2.775
M. Bashiry, H. Hoseini, Abdoreza Mohammadi, E. Sadeghi, Nader Karimian-khosroshahi, F. Barba, A. Khaneghah
Polyamines, including putrescine, spermidine, and spermine, are biological compounds present in nearly all food items. Their desirable physiological effects include cell division and growth. Hence, are undesirable in the diet of patients with tumor. This study aimed to assess the impact of curing agents (sodium chloride (0–2 g), sodium nitrite (0–200 ppm), sodium polyphosphate (0–0.5 g), and ascorbic acid (0–500 ppm)), cooking (frying (180°C), and boiling (100°C)) on polyamine contents in turkey breast meat using response surface methodology based on central composite design and dispersive liquid-liquid microextraction. Postprocessing changes were investigated using a high-performance liquid chromatography equipped with an ultraviolet detector. Study outcomes showed the presence of sodium chloride, sodium nitrite, and sodium polyphosphate in turkey meat reduced the putrescine and spermine content significantly (P < 0.0001). The addition of ascorbic acid as a curing agent slightly increased the concentration of polyamines, while no significant linear effects were associated with the thermal processes. The study observed that curing agents like sodium chloride, sodium nitrite, sodium polyphosphate, and ascorbic acid at 2 g, 200 ppm, 0.5 g, and 382 ppm, respectively, in frying mode minimized spermine and putrescine content with more than 96% desirability. In conclusion, curing additives and cooking are promising procedures for polyamine reduction in turkey breast meat.
多胺,包括腐胺、亚精胺和精胺,是存在于几乎所有食品中的生物化合物。其理想的生理作用包括细胞分裂和生长。因此,在肿瘤患者的饮食中是不可取的。本研究旨在评估固化剂(氯化钠(0-2 g)、亚硝酸钠(0-200 ppm)、聚磷酸钠(0-0.5 g)和抗坏血酸(0-500 ppm))、烹饪(油炸(180°C)和煮沸(100°C))对火鸡胸肉中多胺含量的影响,采用基于中心复合设计和分散液液微萃取的响应面法。采用配备紫外检测器的高效液相色谱法研究后处理变化。研究结果表明,在火鸡肉中添加氯化钠、亚硝酸钠和聚磷酸钠显著降低了腐胺和精胺的含量(P < 0.0001)。添加抗坏血酸作为固化剂,多胺的浓度略有增加,而与热过程没有显著的线性影响。研究发现,在煎炸模式下,氯化钠、亚硝酸钠、聚磷酸钠和抗坏血酸等固化剂分别为2g、200ppm、0.5 g和382 ppm,可将精胺和腐胺的含量降至最低,可取率超过96%。总之,固化添加剂和烹饪是减少火鸡胸肉中多胺的有前途的方法。
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引用次数: 5
Effects of co-inoculation and sequential inoculation of Wickerhamomyces anomalus and Saccharomyces cerevisiae on the physicochemical properties and aromatic characteristics of longan (Dimocarpus longan Lour.) wine 反常柳条霉与酿酒酵母菌共接种和序次接种对龙眼酒理化特性和香气特性的影响
IF 4 3区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-05-19 DOI: 10.15586/QAS.V13I2.893
Xiaozhu Liu, Yinfeng Li, Jichuang Zhou, Mingzheng Huang
Wickerhamomyces anomalus and Saccharomyces cerevisiae were mixed by co-inoculation or sequential inocula-tion, and the physicochemical properties, electronic sensory characteristics, and aromatic characteristics of longan (Dimocarpus longan Lour.) wine were evaluated to analyze the effects of mixed fermentation on wine quality. The results demonstrate that mixed fermentation obtained by co-inoculation or sequential inoculation decreases the alcohol content of longan wine. Furthermore, mixed fermentation also leads to the reduction of the electronic sensory acidity and richness of longan wine. Moreover, the two mixed inoculation methods resulted in different effects on the aromatic characteristics of longan wine. The varieties of aldehyde and ketone aromatic compounds increase in longan wine fermented by co-inoculation, with increasing amounts of acids, aldehydes, ketones, and other compounds, and a decrease in the amounts of ester compounds. However, the variety of ester aromatic compounds and the amounts of acids, aldehydes, and ketones increase when using sequential inoculation. Therefore, the application of mixed fermentation can regulate the physicochemical properties, as well as the electronic sensory characteristics and aromatic characteristics of longan wine, and this contributes to the enrichment of the different types of longan wine.
采用共接种或连续接种的方法,将异头Wickerhamomyces anomalus和酿酒酵母混合,对桂圆葡萄酒的理化性质、电子感官特性和芳香特性进行了评价,分析了混合发酵对葡萄酒品质的影响。结果表明,共接种或连续接种的混合发酵可降低桂圆酒的酒精含量。此外,混合发酵还降低了桂圆酒的电子感官酸度和丰富度。此外,两种混合接种方法对桂圆酒的芳香特性产生了不同的影响。共接种发酵的桂圆酒中醛、酮芳香化合物的种类增加,酸、醛、酮等化合物的含量增加,酯类化合物的含量减少。然而,当使用顺序接种时,酯芳香族化合物的种类和酸、醛和酮的量会增加。因此,混合发酵的应用可以调节桂圆酒的理化特性、电子感官特性和芳香特性,有助于丰富不同类型的桂圆酒。
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引用次数: 4
Neurotoxicity mechanism of Ochratoxin A 赭毒素A的神经毒性机制
IF 4 3区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2021-04-27 DOI: 10.15586/QAS.V13I2.837
F. Nourbakhsh, E. Tajbakhsh
Mycotoxins, such as Ochratoxins, are widely distributed in nature and are common contaminants of human foodstuffs. Ochratoxins are a group of mycotoxins produced by a wide range of molds. Ochratoxin A (OTA), the most prominent member of this toxin family, is produced by various Aspergillus and Penicillium species. OTA is frequently found in foods such as cereals, oleaginous seeds, coffee, and meat products. This mycotoxin has been described as teratogenic, genotoxic, carcinogenic, and immunotoxic, and has been proven to be a potent neurotoxin. In the present study, the neurotoxicological perspective of OTA was reviewed and discussed. The main possible mechanisms of neurotoxicity are oxidative DNA, protein and lipid damage, and apoptosis. However, further studies are needed to conclude the exact neurotoxicity mechanism of OTA and find the approaches that reduce the neurotoxicity induced by OTA.
真菌毒素,如赭毒素,在自然界中广泛分布,是人类食品中常见的污染物。赭毒素是一组由多种霉菌产生的真菌毒素。Ochratoxin A(OTA)是该毒素家族中最突出的成员,由各种曲霉和青霉产生。OTA经常出现在谷物、含油种子、咖啡和肉制品等食品中。这种真菌毒素被描述为致畸、基因毒性、致癌和免疫毒性,并已被证明是一种强效神经毒素。本文对OTA的神经毒性进行了综述和讨论。神经毒性的主要可能机制是DNA氧化、蛋白质和脂质损伤以及细胞凋亡。然而,还需要进一步的研究来总结OTA的确切神经毒性机制,并找到减少OTA诱导的神经毒性的方法。
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引用次数: 28
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Quality Assurance and Safety of Crops & Foods
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