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Post-operative outcomes, including opioid utilization and length of stay, following total knee arthroplasty: A retrospective case matched series comparing conventional and robotic-assisted total knee arthroplasty 全膝关节置换术后的术后结果,包括阿片类药物的使用和住院时间:回顾性的病例匹配系列比较传统和机器人辅助的全膝关节置换术
Pub Date : 2022-11-26 DOI: 10.15438/rr.12.1.302
J. Pearson, Thomas J Schlierf, Kathy Zhang, Jeffrey T. Hodrick
Keywords Total Knee Arthroplasty, robotic-assisted, opioid use Background With the rise of robotic arm-assisted total knee arthroplasty (TKA) cases, there is a need to determine if there are clinical benefits associated with this technology. The purpose of this study was to further evaluate if robotic-assisted TKAs result in improved inpatient post-operative outcomes compared to conventional TKAs. Materials and Methods After IRB approval, a retrospective chart review of 100 robotic-assisted primary TKAs and 100 matched controls undergoing conventional TKA was performed. Patients underwent primary TKA from 2016 to 2018 with minimum 6-month postoperative follow-up by a single fellowship-trained arthroplasty surgeon at a high-volume joint center. Exclusion criteria included <6 month postoperative follow-up, incomplete chart information, inflammatory arthritis, and BMI >40. Demographics and post-operative outcomes, including length of stay (LOS), opioid consumption, duration of opioid use, and discharge status, were recorded. Results There were no significant differences in pre-operative demographics between the two groups. A decrease in LOS (1.58 vs. 2.18 days, p < 0.001) and morphine equivalents (73.52 vs. 102.50, p = 0.017) was reported for the robotic TKA group compared to the control group. The robotic group also reported fewer patients at six weeks postoperatively requiring opioids compared to the control group (37 vs. 61, p = 0.001). Average KOOS Jr at 6-months postoperatively was 81.73 for the control group and 78.22 in the robotic group (p = 0.039). Conclusion Robotic-assisted TKA patients experienced significantly decreased LOS, morphine equivalents, and opioid usage at 6-week postoperatively, indicating that there are early clinical benefits of robotic-assisted TKA. No significant differences between the robotic and control groups were reported in pre-operative KOOS Jr. Although average 6-month postoperative KOOS Jr was slightly higher for the control group, the difference was clinically insignificant. Our average KOOS Jr for both cohorts was higher than the national 1-year postoperative average, 76.8.
背景随着机械臂辅助全膝关节置换术(TKA)病例的增加,有必要确定该技术是否具有临床益处。本研究的目的是进一步评估与传统tka相比,机器人辅助tka是否能改善住院患者的术后预后。材料和方法经IRB批准后,对100名机器人辅助初级TKA和100名接受常规TKA的匹配对照组进行回顾性图表审查。患者在2016年至2018年期间接受了原发性TKA,术后至少6个月由一名在大容量关节中心接受过培训的关节置换外科医生进行随访。排除标准包括40例。记录人口统计学和术后结果,包括住院时间(LOS)、阿片类药物消耗、阿片类药物使用持续时间和出院状况。结果两组术前人口统计学差异无统计学意义。与对照组相比,机器人TKA组的LOS (1.58 vs. 2.18天,p < 0.001)和吗啡当量(73.52 vs. 102.50, p = 0.017)下降。与对照组相比,机器人组术后6周需要阿片类药物的患者也较少(37对61,p = 0.001)。对照组术后6个月平均KOOS Jr为81.73,机器人组为78.22 (p = 0.039)。结论机器人辅助TKA患者术后6周的LOS、吗啡当量和阿片类药物使用显著降低,表明机器人辅助TKA具有早期临床益处。机器人组与对照组术前KOOS Jr无显著差异。尽管对照组术后6个月平均KOOS Jr略高,但差异无临床意义。两组患者的平均kos Jr均高于全国术后1年平均值76.8。
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引用次数: 0
Tranexamic Acid Should be Considered for High Risk Arthroplasty Patients 高危关节置换术患者应考虑使用氨甲环酸
Pub Date : 2022-10-15 DOI: 10.15438/rr.12.1.299
Andy Ho, D. Campbell, S. Yapa, I. Malek, P. Yates
Background Tranexamic acid significantly reduces blood loss and transfusion requirements in arthroplasty patients.  However, it is often avoided in patients who have had previous arterial and thromboembolic disease despite the absence of evidence of hazard in this group of patients. We examined the use of tranexamic acid in unselected hip and knee arthroplasty patients including those considered to be ‘high risk’.   Methods A 2-year retrospective multicentre study was performed with patients who underwent hip or knee arthroplasty surgery. A blood management protocol included universal tranexamic acid use for all patients. Blood loss, transfusion volumes and complications were analysed.   Results A total of 958 patients were included in the study, 130 patients were considered ‘high risk’ of thromboembolic complications and 828 patients were considered ‘low risk’. 879 patients received tranexamic acid with a significant reduction in blood loss (p<0.001) in these patients. Two of 130 (1.5%) ‘high risk’ patients and 14 of 828 (1.7%) ‘low risk’ patients had post-operative VTE. There was no significant difference in rate of VTE between the ‘high risk’ and ‘low risk’ patients (p=0.6) or in the subgroup of ‘high risk’ patients who had received TXA (p=1).   Conclusions The efficacy of tranexamic acid is overwhelming and outweighs any potential risks. Tranexamic acid should be considered for use in all arthroplasty patients including those with prior history of venous or arterial thrombosis.
背景氨甲环酸显著降低关节成形术患者的失血和输血需求。然而,尽管没有证据表明这类患者存在危险,但在既往患有动脉和血栓栓塞疾病的患者中,通常会避免使用这种药物。我们检查了氨甲环酸在未经选择的髋关节和膝关节置换术患者中的使用情况,包括那些被认为是“高危”的患者。方法对接受髋关节或膝关节置换术的患者进行为期2年的回顾性多中心研究。血液管理方案包括所有患者普遍使用氨甲环酸。分析了失血量、输血量和并发症。结果共有958名患者被纳入研究,130名患者被视为血栓栓塞并发症的“高风险”患者,828名患者被认为是“低风险”患者。879名患者接受了氨甲环酸治疗,这些患者的失血量显著减少(p<0.001)。130名“高危”患者中有2名(1.5%)和828名“低风险”患者中的14名(1.7%)患有术后VTE。“高风险”和“低风险”患者之间的VTE发生率没有显著差异(p=0.6),或在接受过TXA的“高风险“患者亚组中(p=1)。结论氨甲环酸的疗效是压倒性的,并且超过了任何潜在的风险。氨甲环酸应考虑用于所有关节成形术患者,包括有静脉或动脉血栓形成病史的患者。
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引用次数: 0
Can Knees be Forgotten 2 Years After Total Knee Arthroplasty? 全膝关节置换术后2年会忘记膝盖吗?
Pub Date : 2022-10-15 DOI: 10.15438/rr.12.1.248
R. Bansal, Angad Jolly, Easwar Balasubramaniana, Shamsundar Yalamanchalia
Background:There have been multiple ways to measure outcomes post total knee arthroplasty. Ultimate goal is to replicate a natural joint to allow patients to perform most activities of daily living and give high satisfaction rates. Patient reported outcome measures (PROM) like Forgotten Joint Score (FJS), Oxford Knee Score (OKS)and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) have been validated and used for evaluation of TKA patients. FJS helps to evaluate how natural a prosthesis feels post surgery. Our aim was to study how natural a joint felt or was forgotten 2 year after surgery and how FJS correlates with OKS and WOMAC scores.Materials and Methods :We evaluated 254 total knee replacements with minimum 2 year post TKA. All the patients who were at least 2 year post operative, completed FJS questionnaire where scores are ranged from 0-100; OKS questionnaire where scores are ranged between 0-48; Short – form WOMAC questionnaire where scores are ranged between 0-28. Correlation analysis was performed for FJS with OKS and short - form WOMAC scores. Results:254 patients with mean age of 65.01 years of which 83 males and 171 females were evaluated with minimum of 24 months follow up and average follow-up of 30.85 months. Average FJS, OKS and SF WOMAC were 77.24, 38.75 & 79.97 respectively. FJS showed good correlation with OKS and SF WOMAC scores.Conclusion :FJS is an easy and equally effective outcome measure, which is valid and reliable like the other common well know measures like OKS and WOMAC. Patients experience a marked improvement in the FJS over the first two years. Patients in our series had good outcomes who had more natural feel of knees or a feeling of “forgotten knees” in their day to day activity after 2 years of surgery.  
背景:有多种方法测量全膝关节置换术后的结果。最终目标是复制一个自然的关节,使患者能够进行大多数日常生活活动,并给予高满意度。患者报告的结果测量(PROM),如遗忘关节评分(FJS),牛津膝关节评分(OKS)和西安大略省和麦克马斯特大学骨关节炎指数(WOMAC)已被验证并用于评估TKA患者。FJS有助于评估假体术后的自然感觉。我们的目的是研究术后2年关节的自然感觉和遗忘程度,以及FJS与OKS和WOMAC评分的相关性。材料和方法:我们评估了254例TKA术后至少2年的全膝关节置换术。所有术后至少2年的患者完成FJS问卷,得分范围为0-100分;OKS问卷,得分在0-48之间;简短的WOMAC问卷,得分范围在0-28之间。FJS与OKS和短格式WOMAC评分进行相关性分析。结果:254例患者,平均年龄65.01岁,其中男性83例,女性171例,随访时间最小24个月,平均30.85个月。FJS、OKS和SF WOMAC的平均评分分别为77.24、38.75和79.97。FJS与OKS、SF WOMAC评分有较好的相关性。结论:FJS是一种简便且同样有效的结局测量方法,与OKS、WOMAC等常见的测量方法一样有效可靠。患者的FJS在前两年有明显的改善。我们研究的患者在经过2年的手术后,在日常活动中膝盖感觉更自然,或者感觉“遗忘膝盖”,结果都很好。
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引用次数: 0
A Literature-Based Resource for the Development of Outpatient Arthroplasty Patient Selection Criteria 基于文献的门诊关节成形术患者选择标准发展资源
Pub Date : 2021-10-12 DOI: 10.15438/rr.11.1.280
Joseph S. Gondusky, Richard R. Pahapill, Christian Coulson
Total joint arthroplasty (TJA) is moving towards the outpatient setting. Teams must develop patient selection criteria to ensure appropriate candidates are treated at the optimal site of care.  Protocols and recommendations have been developed to aid care teams in developing patient selection criteria, but these come from multiple disparate sources.  We review the available literature on patient selection criteria and optimization in the outpatient TJA population, and synthesize this information into a workable format for care design.  We hope to provide a resource to stakeholders that can be tailored to their unique outpatient facility.    Keywords: Total joint arthroplasty, outpatient, same day discharge, selection criteria, patient optimization.
全关节置换术(TJA)正在向门诊治疗方向发展。团队必须制定患者选择标准,以确保合适的候选人在最佳护理地点接受治疗。已经制定了方案和建议,以帮助护理团队制定患者选择标准,但这些标准来自多个不同的来源。我们回顾了门诊TJA患者选择标准和优化的现有文献,并将这些信息综合为护理设计的可行格式。我们希望为利益相关者提供一种资源,可以根据他们独特的门诊设施进行定制。关键词:全关节置换术,门诊,当日出院,选择标准,患者优化。
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引用次数: 0
Life Lost Too Soon: Navy Corpsman from Ohio Killed in Afghanistan Attack August 26, 2021 生命过早逝去:2021年8月26日,俄亥俄州海军士兵在阿富汗袭击中丧生
Pub Date : 2021-10-12 DOI: 10.15438/rr.11.1.290
T. Mctighe
Navy Corpsman Maxton “Max” W. Soviak, HM3 (22 years old) of Berlin Heights, Ohio, was one of the 13 U.S. service members killed while supporting non-combatant evacuation operation in Kabul, Afghanistan. Max was advanced to the rank of Hospital Corpsman Third Class “as a result of his brave actions in support of fellow service members,” according to a Navy statement. He was also posthumously awarded the Purple Heart and Fleet Marine Force Corpsman warfare badge.
俄亥俄州柏林高地HM3海军下士Maxton“Max”W.Soviak(22岁)是在阿富汗喀布尔支持非战斗人员撤离行动时遇难的13名美国军人之一。根据海军的一份声明,马克斯被提升为三级医院医务人员,“因为他勇敢地支持战友”。他还被追授紫心勋章和舰队海军陆战队士兵战徽章。
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引用次数: 0
Early Term Radiographic Follow-Up of the Trident Tritanium Acetabular Component 三叉戟氚髋臼组件的早期X线随访
Pub Date : 2021-05-25 DOI: 10.15438/RR.11.1.273
D. Deboer, Jeffrey T. Hodrick, M. Christie
INTRODUCTION: The purpose of this study was to evaluate the two year clinical and radiographic outcomes of patients undergoing a primary total hip arthroplasty (THA) using the Trident Tritanium primary Cup.   METHODS: 197 patients who underwent a direct anterior THA using a Tritanium acetabular component between 2011 and 2015 were retrospectively reviewed by two surgeons from a single institution. The investigators, along with an independent physician, separately reviewed radiographs blinded to clinical data looking for radiolucent lines adjacent to the acetabular cup using the Charnley-DeLee zones. Clinical results were measured using acetabular revision surgery as an end point for failure. According to the American Academy of Orthopaedic Surgeons Levels of Evidence, this study was consistent with a Level III Therapeutic study.   RESULTS: 101 (48.73%) subjects did not exhibit any radiolucent lines around the acetabular component. 53 (26.90%) subjects displayed radiolucency in only one zone. 27 (13.71%) subjects displayed radiolucency in two zones, and 16 (8.12%) displayed radiolucency in all three zones. Radiolucency was most prevalent in zone 1 at 2 years with 83 (42.13%) subjects displaying radiolucency. There were five (2.54%) acetabular failures within two years of the index surgery. Of those 5 subjects, 3 displayed radiolucency in 1 zone, 2 displayed radiolucency in >1 zone, and 2 displayed radiolucencies >1 mm.   CONCLUSION: In our study, the Tritanium Cup demonstrated a 2.54% failure rate for aseptic loosening at 2 year follow-up. In addition, 48.73% of patients displayed a radiolucent line in at least one Charnley-DeLee zone. We also observed a progression of radiolucencies between the 6 month radiographs and the 2 year radiographs.
引言:本研究的目的是评估使用Trident Tritanium初级杯进行初次全髋关节置换术(THA)的患者两年的临床和放射学结果。方法:来自同一机构的两名外科医生对2011年至2015年间使用Tritanium髋臼组件进行直接前THA的197名患者进行了回顾性分析。研究人员和一名独立医生分别审查了对临床数据不知情的射线照片,使用Charnley-DeLee区寻找髋臼杯附近的射线透射线。将髋臼翻修手术作为失败的终点来测量临床结果。根据美国骨科医师学会的证据水平,这项研究与III级治疗研究一致。结果:101名(48.73%)受试者髋臼组件周围未出现任何射线透射线。53名(26.90%)受试者仅在一个区域显示出射线可透过性。27名(13.71%)受试者在两个区域显示出射线可透过性,16名(8.12%)受试人员在所有三个区域都显示出射线可透性。2岁时,1区的放射透光度最为普遍,83名(42.13%)受试者显示出放射透光度。指数手术后两年内有5例(2.54%)髋臼失败。在这5名受试者中,3人在1个区域显示出射线可透过性,2人在>1个区域显示为射线可透过,2人显示为>1 mm。结论:在我们的研究中,Tritanium Cup在2年的随访中显示出2.54%的无菌性松动失败率。此外,48.73%的患者在至少一个Charnley-DeLee区显示出射线可透过线。我们还观察到,在6个月的射线照片和2年的射线照片之间,射线可透过性有进展。
{"title":"Early Term Radiographic Follow-Up of the Trident Tritanium Acetabular Component","authors":"D. Deboer, Jeffrey T. Hodrick, M. Christie","doi":"10.15438/RR.11.1.273","DOIUrl":"https://doi.org/10.15438/RR.11.1.273","url":null,"abstract":"INTRODUCTION: The purpose of this study was to evaluate the two year clinical and radiographic outcomes of patients undergoing a primary total hip arthroplasty (THA) using the Trident Tritanium primary Cup. \u0000  \u0000METHODS: 197 patients who underwent a direct anterior THA using a Tritanium acetabular component between 2011 and 2015 were retrospectively reviewed by two surgeons from a single institution. The investigators, along with an independent physician, separately reviewed radiographs blinded to clinical data looking for radiolucent lines adjacent to the acetabular cup using the Charnley-DeLee zones. Clinical results were measured using acetabular revision surgery as an end point for failure. According to the American Academy of Orthopaedic Surgeons Levels of Evidence, this study was consistent with a Level III Therapeutic study. \u0000  \u0000RESULTS: 101 (48.73%) subjects did not exhibit any radiolucent lines around the acetabular component. 53 (26.90%) subjects displayed radiolucency in only one zone. 27 (13.71%) subjects displayed radiolucency in two zones, and 16 (8.12%) displayed radiolucency in all three zones. Radiolucency was most prevalent in zone 1 at 2 years with 83 (42.13%) subjects displaying radiolucency. There were five (2.54%) acetabular failures within two years of the index surgery. Of those 5 subjects, 3 displayed radiolucency in 1 zone, 2 displayed radiolucency in >1 zone, and 2 displayed radiolucencies >1 mm. \u0000  \u0000CONCLUSION: In our study, the Tritanium Cup demonstrated a 2.54% failure rate for aseptic loosening at 2 year follow-up. In addition, 48.73% of patients displayed a radiolucent line in at least one Charnley-DeLee zone. We also observed a progression of radiolucencies between the 6 month radiographs and the 2 year radiographs.","PeriodicalId":20884,"journal":{"name":"Reconstructive Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46841803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Cementless Total Hip Arthroplasty. A Multicentre Prospective Minimum 2 Year Follow-up Clinical Outcomes Study. 新型无骨水泥全髋关节置换术。一项多中心前瞻性至少2年随访临床结果研究。
Pub Date : 2021-04-08 DOI: 10.15438/RR.11.1.251
Rohit Pandey, S. Coffey, R. Sorial
Background: Cementless implants were introduced approximately three decades ago in order to address aseptic loosening of cemented hip prostheses with the aim of early mobilisation, better functional result and bone stock preservation. The primary objective of this study is to introduce a new cementless HA coated implant and report its minimum 2 year follow up results.Material & method: This is a prospective, multi-centre, consecutive series, clinical outcomes study with 75 patients. Inclusion criteria for the study were age 21- 85 years, BMI <40, osteoarthritis of the hip.Patients were operated using a standard posterolateral approach. The Paragon stem and the Global cup were implanted in a cementless method. Patients were reviewed at 6 weeks, 6 months and two years postoperative. At each visit AQoL 6D, VAS Pain, Oxford Hip Score were recorded. Post-operative X-Rays were reviewed at immediate post-operative, 6 months and two years.Results: Mean duration of surgery was 63.1 min with range of 40-120 min. AQoL over time changed from pre-op mean 50.51, at 6 weeks and at 2 years mean 35.06. Oxford hip score had upward trend from pre-op to post-op 6wks assessments and a plateau in following assessments. VAS pain trajectories, showing a clear downward trend from pre-op to post-op 6wks and a plateau in the following postoperative assessments.Discussion & conclusion: The combination of Paragon stem and Global cup incorporates proven features of successful implants. The unique feature of lateral tension grooves and progressive neck dimension with dual offset options. This combination has shown promising early results with early follow up of a minimum of 2 years, with a 100% survivorship of the stem and 98.7% survivorship overall for any reason and is a good cementless option in THA.
背景:大约三十年前,为了解决骨水泥髋关节假体的无菌性松动问题,引入了无骨水泥植入物,目的是早期动员、更好的功能结果和骨储备保存。本研究的主要目的是介绍一种新型无骨水泥HA涂层植入物,并报告其至少2年的随访结果。材料和方法:这是一项前瞻性、多中心、连续系列的临床结果研究,共有75名患者。该研究的纳入标准为年龄21-85岁,BMI<40,髋关节骨性关节炎。患者采用标准后外侧入路进行手术。Paragon干和Global cup采用非骨水泥方法植入。在术后6周、6个月和2年对患者进行复查。每次就诊时记录AQoL 6D、VAS疼痛、Oxford髋关节评分。术后X光检查在术后即刻、6个月和两年进行。结果:手术的平均持续时间为63.1分钟,范围为40-120分钟。随着时间的推移,AQoL从术前的平均值50.51、6周和2年的平均值35.06变化。从术前到术后6周的评估,牛津髋关节评分呈上升趋势,随后的评估呈平稳状态。VAS疼痛轨迹,从术前到术后6周显示出明显的下降趋势,在随后的术后评估中呈平稳状态。讨论和结论:Paragon干细胞和Global cup的结合结合了成功植入的公认特征。独特的横向张力凹槽和渐进式颈部尺寸,可选择双偏置。该组合已显示出有希望的早期结果,早期随访至少2年,干细胞存活率为100%,无论出于何种原因,总存活率为98.7%,是THA的一个良好的非骨水泥选择。
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引用次数: 0
Cementless Highly Porous Titanium Tibial Base Plate in Total Knee Arthroplasty – Midterm Outcomes. 全膝关节置换术中无骨水泥高多孔钛胫骨基板的中期结果。
Pub Date : 2021-02-05 DOI: 10.15438/RR.11.1.235
Smit N. Shah, N. Coulshed, R. Sorial
Introduction & Aims TKA in more active and young patients has prompted the interest in more durable and biological methods of Osteo-integration with cementless components. With the emergence of improved biomaterials like porous titanium and the success, search for a cementless TKA with long-term durability and survivorship may have ended. This is a retrospective study of 492 consecutive TKAs using Cementless tibial fixation, reporting on the early 4 years clinical and radiological outcomes. Method We studied 492 TKAs performed consecutively by a single surgeon between 1stJan. 2010 and 31stDec. 2015 using a cementless, fixed bearing tibial tray (porous–Regenerex, Vanguard, Zimmer-Biomet) and a cementless femoral component (Vanguard) with no exclusion criteria. Clinical and radiological follow-up was done on these patients and in addition a comprehensive joint registry review was performed on the whole cohort (Level II evidence). Results  The average Knee Society Score at final follow-up was 89.33, average pre-op being 42.06. Average post-op WOMAC score was 43.45 and average pre-op was 77.78. On radiological examination, no patients had osteolysis around tibial base plate. In our series 9 patients were revised, out of which only 4 patients had the tibial tray and femoral component revised and 5 patients had patella resurfacing or liner exchange. Overall survivorship of the cementless tibial component is excellent with a survivorship of 99.4% at 5.9 years based on a comprehensive AOANJRR data. Conclusions Cementless tibial fixation using a porous titanium construct  can provide stable bone ingrowth fixation on the tibial side with excellent and predictable early 4 to 5 year clinical and radiological outcomes.
引言和目的TKA在更活跃和年轻的患者中引起了人们对骨与非骨水泥成分整合的更持久和生物方法的兴趣。随着多孔钛等改良生物材料的出现和成功,寻找具有长期耐久性和存活率的无水泥TKA可能已经结束。这是一项对492例使用非骨水泥胫骨内固定的连续TKA的回顾性研究,报告了早期4年的临床和放射学结果。方法我们研究了492例TKA,由一名外科医生于1月1日连续进行。2010年和12月31日。2015年,使用无骨水泥固定胫骨托(多孔Regenerex、Vanguard、Zimmer Biomet)和无骨水泥股骨组件(Vanguard),无排除标准。对这些患者进行了临床和放射学随访,此外对整个队列进行了全面的联合登记审查(II级证据)。结果最终随访时膝关节社会评分平均为89.33,术前平均为42.06。术后WOMAC平均得分为43.45,术前平均得分为77.78。在放射学检查中,没有患者出现胫骨底板周围骨溶解。在我们的系列中,9名患者接受了翻修,其中只有4名患者进行了胫骨托和股骨组件的翻修,5名患者进行髌骨表面置换或衬垫置换。根据AOANJRR的综合数据,非骨水泥胫骨组件的总生存率非常好,5.9年时的生存率为99.4%。结论使用多孔钛结构的非骨水泥胫骨内固定可以在胫骨侧提供稳定的骨向内生长固定,并具有良好的可预测的早期4至5年的临床和放射学结果。
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引用次数: 0
Intravenous versus Intra-Articular Tranexamic Acid in Primary Total Hip Arthroplasty: A Prospective Randomised Double Blinded Non-Inferiority Trial 初次全髋关节置换术中静脉注射与关节内注射氨甲环酸:一项前瞻性随机双盲非效性试验
Pub Date : 2021-02-05 DOI: 10.15438/RR.11.1.245
A. Hasan, D. Campbell, P. Lewis
Background: Tranexamic acid (TXA) has been shown to be effective in reducing post-operative blood loss after hip replacement surgery. Clinicians can be reluctant to administer intravenous (IV) TXA to high risk patients and intra-articular (IA) administration has been proposed as an alternative mode of delivery. This study was conducted to compare the efficacy of IV versus IA administration of TXA. This prospective, double blinded, randomised non-inferiority trial, compared 69 patients undergoing primary total hip arthroplasty (THA) who received either 3 doses of 15mg/kg of IV TXA or 3 g of IA TXA after capsular closure. The primary outcomes were change in Hb and the rate of blood transfusion. The secondary outcome was the rate of VTE. Results: The mean haemoglobin level change from pre-operative to day 1 post-operative for the IV group was 26.7g/L and for IA group was 27.3g/L. No statistically significant difference was detected between the two groups (p=0.82). No patients required a transfusion or developed a VTE. Conclusions: IA administration of TXA can be equally effective as IV in the reduction of blood loss and the prevention of post-operative anaemia in primary THA. Background
背景:氨甲环酸(TXA)已被证明能有效减少髋关节置换术后的术后失血。临床医生可能不愿意给高危患者静脉注射(IV)TXA,关节内注射(IA)已被提议作为一种替代分娩方式。本研究旨在比较静脉注射与IA给药TXA的疗效。这项前瞻性、双盲、随机非劣效性试验比较了69名接受原发性全髋关节置换术(THA)的患者,这些患者在包膜闭合后接受了3剂15mg/kg静脉注射TXA或3 g IA TXA。主要结果是Hb和输血率的变化。次要结果是VTE的发生率。结果:静脉注射组术前至术后第1天的平均血红蛋白水平变化为26.7g/L,IA组为27.3g/L。两组之间没有统计学显著差异(p=0.82)。没有患者需要输血或发生VTE。结论:TXA的IA给药与IV给药在减少原发性THA患者的失血和预防术后贫血方面同样有效。背景
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引用次数: 1
Low Transfusion Rate Attainable in Anterior Approach Total Hip Arthroplasty Utilizing a Modern Protocol 采用现代方案的前路全髋关节置换术可达到低输血率
Pub Date : 2021-02-05 DOI: 10.15438/RR.11.1.247
Joseph S. Gondusky, Benjamin C. Campbell, C. Coulson
Background: Transfusion is a known risk of total hip arthroplasty (THA). It has been associated with a multitude of medical complications and increased cost. Prior studies report transfusion rates associated with THA, with wide variation, but most cannot differentiate the surgical approach utilized. The anterior approach (AA) for THA has been associated with increased operative time, complications, and blood loss, but little data exists regarding the actual transfusion rate associated with the approach. Methods: We performed a retrospective review of 390 consecutive, elective, primary unilateral AA THA procedures. Patient demographic, clinical and perioperative data was analyzed. A modern perioperative pathway, including a simple protocol to limit blood loss, is defined. Results: The group consisted of a typical inpatient arthroplasty population, with wide ranges of age, body mass index (BMI), and health status. The average age was 64.05 years (+ 10.67, range 27-94). BMI averaged 29.76 kg/m2 (+ 5.98, range 16-47). The majority of patients were American Society of Anesthesiologists (ASA) class 2 (45.6%) or 3 (50.3%), with 10 patients ASA 4 (2.6%). Average preoperative hemoglobin was 13.48 g/dL (+ 1.47, range 9.118.2). Operative time averaged 91.22 minutes (+ 14.2). 83.3% of patients received a spinal anesthetic. Most patients were discharged on postoperative day one (93.1%) to home (99%). Estimated blood loss averaged 264mL (+ 95.19, range 100-1000). No patient required perioperative transfusion or readmission for symptomatic anemia within 30 days postoperative. Conclusion: A modern protocol we utilize and define is capable of limiting blood loss and transfusion risk in anterior approach total hip arthroplasty.
背景:输血是已知的全髋关节置换术(THA)的风险。它与许多医疗并发症和增加的成本有关。先前的研究报告了与THA相关的输血率,差异很大,但大多数无法区分所使用的手术方法。THA的前路入路(AA)与手术时间、并发症和失血增加有关,但关于与该入路相关的实际输血率的数据很少。方法:我们对390例连续、选择性、原发性单侧AA THA手术进行了回顾性分析。对患者人口统计学、临床和围手术期数据进行分析。定义了一种现代围手术期途径,包括一种限制失血的简单方案。结果:该组由典型的关节成形术住院人群组成,年龄、体重指数(BMI)和健康状况各不相同。平均年龄64.05岁(+10.67,范围27-94)。BMI平均为29.76 kg/m2(+5.98,范围16-47)。大多数患者为美国麻醉师协会(ASA)2级(45.6%)或3级(50.3%),其中10名患者ASA 4级(2.6%)。术前平均血红蛋白为13.48 g/dL(+1.47,范围9.118.2)。手术时间平均为91.22分钟(+14.2)。83.3%的患者接受了脊椎麻醉。大多数患者在术后第一天(93.1%)出院回家(99%)。估计的平均失血量为264毫升(+95.19,范围100-1000)。术后30天内,无患者因症状性贫血需要围手术期输血或再次入院。结论:我们使用和定义的现代方案能够限制全髋关节置换术前入路的失血和输血风险。
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Reconstructive Review
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