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Risk Factors for Blood Transfusion After Primary Total Hip Arthroplasty 全髋关节置换术后输血的危险因素
Pub Date : 2019-11-22 DOI: 10.15438/rr.9.1.226
Kyle Kesler, T. Brown, J. R. Martin, B. Springer, Jesse E. Otero
Aims: In the setting of rising healthcare costs, more cost efficiency in total hip arthroplasty (THA) is required. Following THA, most patients are monitored with serial hemoglobin testing despite few needing blood transfusions.  This testing adds cost and may not be necessary in most patients.  This study aims to identify factors associated with transfusion, therefore guiding hemoglobin monitoring following THA.Patients and Methods: Patients who underwent primary THA in 2015 were identified using the National Surgical Quality Improvement Project (NSQIP) database.  Patient discharged on the day of surgery were excluded. Patients were classified into those receiving transfusion versus no transfusion. Demographics and comorbidities were compared between groups followed by univariate and multivariate analysis, allowing identification of patient characteristics and comorbidities associated with transfusion. Results: Overall, 28664 patients who underwent THA patients were identified.  Within this group, 6.1% (n=1737) had a post-operative transfusion.  Patients receiving a blood transfusion were older, had lower body mass index, and had higher rates of chronic obstructive pulmonary disease (COPD), heart failure, dialysis, prior transfusion, and were more frequently ASA class 3-4 (p 70, diabetes, smoking, COPD, prior transfusion, and operative time >2 hours as independent risk factors for transfusion.Conclusion: Among THA patients, characteristics and comorbidities exist that are associated with increased likelihood of transfusion.  Presence of these factors should guide hemoglobin monitoring post-operatively. Selective hemoglobin monitoring can potentially decrease the cost of THA.
目的:在医疗费用不断上涨的情况下,需要提高全髋关节置换术(THA)的成本效益。THA后,尽管很少有患者需要输血,但大多数患者都接受了连续血红蛋白检测。这种检测增加了成本,对大多数患者来说可能没有必要。本研究旨在确定与输血相关的因素,从而指导THA后的血红蛋白监测。患者和方法:使用国家外科质量改进项目(NSQIP)数据库确定2015年接受原发性THA的患者。手术当天出院的患者除外。患者被分为接受输血和不接受输血的患者。比较各组之间的人口学和合并症,然后进行单变量和多变量分析,从而确定患者特征和与输血相关的合并症。结果:总共确定了28664名接受THA的患者。在这一组中,6.1%(n=1737)接受了术后输血。接受输血的患者年龄较大,体重指数较低,慢性阻塞性肺病(COPD)、心力衰竭、透析、既往输血的发生率较高,更常见的是ASA 3-4级(p 70,糖尿病、吸烟、慢性阻塞性肺病、既往输血和手术时间>2小时是输血的独立危险因素。结论:在THA患者中,存在与输血可能性增加相关的特征和合并症。这些因素的存在应指导术后血红蛋白监测。选择性血红蛋白监测可能降低THA的成本。
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引用次数: 2
Long-Term Screening is Necessary in Patients with Metal on Metal Total Hip Arthroplasty 金属对金属全髋关节置换术患者的长期筛查是必要的
Pub Date : 2019-11-15 DOI: 10.15438/rr.9.1.225
J. R. Martin, S. Odum, W. Griffin
Introduction: Adverse reactions to metal debris with catastrophic failures have been seen with a number of metal on metal (MoM) total hip designs. Understanding survivorship and factors associated with failure will allow for more targeted surveillance of those patients at highest risk for failure. The purpose of this study was to assess the mid to long term survivorship and specific factors associated with failure for a large cohort of a single modular MoM design.Methods: Consecutive patients treated with a modular metal on metal bearing with a five to fourteen year follow-up were included. Clinical outcome scores and radiographic data were prospectively collected.  Failure was defined as revision of either component for any reason during the study period. Multiple implant, surgical, and patient factors were analyzed for associations with elevated ion levels or revision due to adverse reactions to metal debris.Results: The average age at the time of surgery for the 253 patients included in the study was 55. There were 28 revisions (7.5%), eight due to metallosis (2%).   Survivorship was 89% at 12.6 years with revision for any reason as the end point. Survivorship was 93% when limited to revision for ALTR as the end point. Time in situ was the only variable that was statistically associated with an increased risk of failure due to ALTR (p<0.0001)Conclusion: In this large series of a single design modular metal-metal total hip we found relatively low rates of revision due to adverse reactions to metal debris.  The only variable associated with a statistically significant risk of ALTR was time in situ.   Therefore, long-term surveillance is necessary in patients with a MoM THA.
导语:金属碎片与灾难性失效的不良反应已经在许多金属对金属(MoM)全髋关节设计中看到。了解生存和与失败相关的因素将允许对那些失败风险最高的患者进行更有针对性的监测。本研究的目的是评估单个模块化MoM设计的大型队列的中长期生存率和与失败相关的特定因素。方法:采用模块化金属对金属轴承治疗的连续患者,随访5 ~ 14年。前瞻性地收集临床结果评分和影像学资料。失败被定义为在研究期间由于任何原因修改了任何一个组成部分。分析了多种种植体、手术和患者因素与金属碎片不良反应引起的离子水平升高或修复的关系。结果:研究中253例患者手术时的平均年龄为55岁。有28个修订(7.5%),8个是由于金属中毒(2%)。12.6年生存率为89%,以任何原因修订为终点。当以ALTR修订为终点时,生存率为93%。原位时间是唯一与ALTR失败风险增加相关的统计学变量(p<0.0001)。结论:在这个单一设计模块化金属-金属全髋关节的大型系列研究中,我们发现由于金属碎片不良反应而进行翻修的比例相对较低。与ALTR有统计学意义的风险相关的唯一变量是原位时间。因此,对MoM THA患者进行长期监测是必要的。
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引用次数: 1
Techniques of Insertion and Early Clinical Impressions with a Short Curved Tissue Sparing Implant for Total Hip Arthroplasty (The French Experience) 全髋关节置换术中短弯曲保留组织假体的置入技术及早期临床印象(法国经验)
Pub Date : 2019-04-08 DOI: 10.15438/RR.9.1.224
G. Venet, A. Tesson, Francois Le Cour Grandmaison, N. Fraquet, D. Brazil, T. Mctighe
Background: Total hip arthroplasty (THA) is one of the most effective orthopedic procedures, providing consistently high success rates across all population segments as measured by pain relief, improved function, and patient satisfaction. However clinical outcomes have been less favorable in young active patients, that lead to the re-development of metal on metal hip resurfacing (HR), with the most successful being the Birmingham Hip Replacement (BHR) introduced in 1997. Evolving complications due to increased metal ion debris has lead to a great reduction of use for all metal on metal (MOM) HR designs, leading many surgeons and patients to look for an alternative surgical selection. This search has focused on the development and use of short stems for THA. One such style of short stems is curved neck preserving designs. This paper will review our French experience with one of those designs.Materials and Methods: This is a retrospective review of four surgeons series of a short curved tissue sparing cementless femoral implant (TSI™ Hip Stem, Signature Orthopaedics) for THA. The femoral component was used with two different cementless acetabular styles (Mathys RM Pressfit, and Zimmer Biomet Allofit®). Results on the cups will not be revived in this paper. 150 TSI™ Stems by four surgeons at the same institution utilizing the posterior surgical approach since September 2016. 40% women, average age 66 years with extremes of 27 to 78 years. 10 cases of dysplastic hips, 6 cases of aseptic osteonecrosis, 1 fracture, 1 rheumatoid coxitis, and the rest primary coxathosis, with 7 patients operated on both hips at the same time. 23.3 % have been Dorr type A canal shape.Results: There has been no aseptic loosing, three femoral components have been explanted due to postoperative infection. There was one intra-operative femoral distal fracture in a Dorr type A bone profile during stem insertion. One posterior dislocation; there has been two patients with thigh pain with pathological bone scan, and one with low back pain and no leg length discrepancies greater than plus or minus 5 mm.Conclusion: This short curved tissue sparing implant has demonstrated excellent initial short-term results, with excellent implant stability, excellent medial calcar bone remodeling with one dislocated stem, two thigh pain and one patient with low back pain. One distal intra-operative fracture in a Dorr type A bone. This has now been addressed with the use of distal sizing gauges and the use of flexible reamers to open the distal canal prior to stem insertion. Removal of the infected stems demonstrated implant stability with early bone attachment in the proximal porous surface. The high neck resection allows for ease of revision and conversion implanting a new primary conventional length cementless stem design.There is a short but definitive learning curve in fitting the implant to the femoral neck versus the standard metaphyseal and diaphyseal conventional style stems.
背景:全髋关节置换术(THA)是最有效的骨科手术之一,通过疼痛缓解、功能改善和患者满意度来衡量,在所有人群中都提供了一致的高成功率。然而,年轻活跃患者的临床结果不太好,这导致金属对金属髋关节置换(HR)的重新发展,最成功的是1997年引入的伯明翰髋关节置换(BHR)。由于金属离子碎片增加导致并发症的不断发展,导致全金属对金属(MOM) HR设计的使用大大减少,导致许多外科医生和患者寻找替代手术选择。本研究的重点是THA短茎的开发和使用。一种这样的短茎是弯曲的颈部保留设计。本文将回顾其中一种设计在法国的经验。材料和方法:这是对四名外科医生为THA使用短弯曲组织保留无水泥股骨植入物(TSI™Hip Stem, Signature orthopatics)的回顾性回顾。股骨假体用于两种不同的无骨水泥髋臼类型(Mathys RM Pressfit和Zimmer Biomet Allofit®)。关于杯子的研究结果在本文中将不再赘述。自2016年9月以来,同一机构的四名外科医生使用后路手术入路进行了150例TSI™茎。40%是女性,平均年龄66岁,极端年龄在27到78岁之间。髋发育不良10例,无菌性骨坏死6例,骨折1例,类风湿性髋炎1例,其余原发性髋臼合并,其中双髋同时手术7例。23.3%为Dorr A型管形。结果:无一例无菌性松动,3例股骨假体因术后感染取出。术中有一例Dorr a型股骨远端骨折。后路脱位1例;有两名患者在病理骨扫描中出现大腿疼痛,一名患者出现腰痛,腿长差异不超过±5毫米。结论:该短弯曲组织保留植入物具有良好的初步短期效果,具有良好的植入物稳定性,良好的内侧跟骨重塑,其中1例脱位,2例大腿疼痛,1例腰痛。术中一例Dorr a型骨远端骨折。现在已经解决了这个问题,使用远端尺寸计和使用柔性铰刀在插入干之前打开远端管。移除受感染的骨干显示了种植体的稳定性,并在近端多孔表面有早期骨附着。高颈部切除使得复位和转换更加容易,植入一种新的初级常规长度无水泥假体设计。与标准干骺端和干骺端常规柄相比,将假体植入股骨颈有一个短暂但明确的学习曲线。
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引用次数: 0
Restoration of Femoral Condylar Anatomy for Achieving Optimum Functional Expectations: Continuation of an Earlier Study At 5-Year Minimum Follow-Up 股骨髁解剖恢复以达到最佳功能期望:延续5年最小随访的早期研究
Pub Date : 2019-04-08 DOI: 10.15438/RR.9.1.222
Sridhar M. Durbhakula, Vinay Durbhakula, Navin S. Durbhakula
BACKGROUND: Studying and reporting the continuous, prospective outcomes of a post-surgical orthopaedic population without loss to follow-up at various standard landmarks over time is rarely achieved in total knee arthroplasty (TKA) literature. Small case series populations reported at an early follow-up time is common, and usually not beyond any initial publication for further reporting. The purpose of this study was to advance the knowledge base of the performance of Freedom Knee system through the continuous monitoring of a previously reported early series TKA patient population.METHODS: A prospective, continuous series of 176 primary posterior stabilized (PS) TKAs were performed in 172 patients by a single surgeon. Femoral component size distribution was assessed and all patients were followed for a minimum of five-years post-operatively. Total Hospital for Special Surgery (HSS) scores and range of motion (ROM) was assessed for the entire cohort and by gender.RESULTS: There were no patients lost to follow-up. Two patients required incision and drainage for superficial wound infection of the indicated knees. One patient required tibial component and polyethylene insert revision following a motor vehicle accident resulting in a proximal tibial fracture and component loosening. There was no radiographic evidence of component failure. As expected, femoral component size frequency use was skewed by gender with the larger sizes in males. There were no pre- or post-operative clinical or functional differences by gender and at the recent follow-up (avg. 6.9 years). In addition, there was an average significant increase in change of HSS score (p<0.001) and ROM (P<0.001) when compared to pre-operative baseline but no significant difference in HSS or ROM between the two and five-year outcome results.CONCLUSIONS: The design characteristic for component sizing and functional expectations were re-confirmed in the reported Western population cohort series, and observed optimum safety, performance and efficacy through five-years. Further continued study efforts of this primary TKA system is warranted across multiple surgeons and all ethnic cultures.
背景:在全膝关节置换术(TKA)的文献中,研究和报道连续的、前瞻性的术后骨科人群的随访结果,而不丢失各种标准标志,这在一段时间内很少实现。在早期随访时报告的小病例系列人群很常见,通常不会超过任何初步出版物以作进一步报告。本研究的目的是通过对先前报道的早期系列TKA患者群体的持续监测来提高自由膝关节系统性能的知识库。方法:一名外科医生对172例患者进行了前瞻性、连续的176例原发性后路稳定(PS) tka。评估股骨假体大小分布,所有患者术后随访至少5年。特殊外科医院(HSS)总分和活动度(ROM)对整个队列和性别进行评估。结果:无患者失访。2例患者指征膝关节浅表伤口感染需切开引流。一名患者因机动车事故导致胫骨近端骨折和部件松动,需要胫骨假体和聚乙烯假体翻修。没有影像学证据表明部件失效。正如预期的那样,股骨假体尺寸的使用频率因性别而异,男性的股骨假体尺寸较大。在最近的随访中(平均6.9年),术前或术后均无临床或功能差异。此外,与术前基线相比,HSS评分(p<0.001)和ROM (p<0.001)的变化平均显著增加,但2年和5年结局之间HSS或ROM无显著差异。结论:在报道的西方人群队列系列中,组件尺寸和功能预期的设计特征得到了再次确认,并在5年内观察到最佳的安全性、性能和疗效。在多名外科医生和所有种族文化背景下,对这种初级TKA系统进行进一步的研究是有必要的。
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引用次数: 2
What is Considered a Conflict of Interest or What to Disclose in Lectures and Publications? 什么被认为是利益冲突或在讲座和出版物中披露什么?
Pub Date : 2019-04-08 DOI: 10.15438/RR.9.1.221
T. Mctighe
Recently our Journal was criticized for allowing a co-author to submit and publish a technical paper when said surgeon is involved in a litigation matter. “I am very surprised indeed that you do not consider being a defendant in legal action concerning the very practice being defended in an article amounts to a conflict of interest.” This made me think it might be an appropriate time to revisit this issue. First I think it is important to understand some of the history regarding disclosure and conflict of interest.
最近,我们的《华尔街日报》因允许一位合著者提交并发表一篇技术论文而受到批评,该论文称外科医生涉及诉讼事宜。“我真的很惊讶,你不认为在一篇文章中被辩护的行为构成利益冲突的法律诉讼中成为被告。”这让我认为现在可能是重新审视这个问题的合适时机。首先,我认为了解一些关于披露和利益冲突的历史是很重要的。
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引用次数: 0
Does Implant Design Affect Hospital Metrics and Patient Outcomes? TKA Utilizing a “Fast-Track” Protocol 植入物设计是否影响医院指标和患者结果?使用“快速通道”协议的TKA
Pub Date : 2019-04-08 DOI: 10.15438/RR.9.1.203
R. Buch, L. Schroeder, Rylie Buch, R. Eberle
Introduction“Fast-Track” protocols have been introduced in TKA with the intention to increase health care savings while maintaining or improving patient outcomes. The influence of the implant design in a “Fast-Track” setting has not been described yet. The primary goal of this study was to compare a customized implant with standard off-the-shelf (OTS) devices when utilizing a “Fast-Track” protocolMethodsSixty-two (62) patients were prospectively enrolled at a single center and implanted with either a customized or a standard off-the-shelf implant resulting in thirty (30) patients being treated with an OTS design and thirty-two (32) with the customized design. The same institutional fast-track protocol was utilized on all patients and included pre-, intra-, and postoperative medical treatment. We assessed total length of stay (LOS), discharge destination and range of motion at 6-8 weeks post-op and at an average of 16 months post-op follow-up to compare the OTS implant with the customized device. Implant survivorship was assessed at a minimum of 25 months post-op.ResultsUsing the fast track protocol we were able to decrease overall LOS to 2.1 days versus 3.6 days prior to introduction of the protocol. The use of the customized implant further reduced LOS significantly to 1.6 days. Significantly higher number of patients who got implanted with the customized device (66%) were discharged within 24 hours than in the OTS group (30%). Patients treated with the customized implant were found to be discharged home more often than patients treated with the OTS implants (97% vs. 80%) and achieved higher range of motion both at 6-8 weeks (114° vs. 101°) and at an average of 16 months (122° vs. 114°) than patients who got treated with the OTS device. At an average follow-up of 28 months, there was 1 implant revision in the customized group (due to tibial fracture resulting from patient fall). For the OTS group there was 1 implant revision (late infection) and 1 poly swap (due to instability).DiscussionBased on our analysis we observed a positive influence of the customized device on patient outcomes and hospital metrics and we therefore conclude that the implant choice is an important factor for TKA in a “fast-track” setting.
在TKA中引入了“快速通道”协议,目的是在保持或改善患者预后的同时增加医疗保健节省。在“快速通道”设置中植入物设计的影响尚未被描述。本研究的主要目的是在使用“快速通道”方案时比较定制种植体与标准现货(OTS)设备。方法在单个中心前瞻性地招募了62(62)名患者,并植入定制或标准现货种植体,结果30(30)名患者接受OTS设计治疗,32(32)名患者接受定制设计治疗。所有患者均采用相同的机构快速通道方案,包括术前、术中和术后治疗。我们在术后6-8周和平均16个月的随访中评估总住院时间(LOS)、出院目的地和活动范围,以比较OTS植入物和定制装置。术后至少25个月评估种植体存活情况。使用快速通道协议,我们能够将总体LOS减少到2.1天,而不是引入协议之前的3.6天。使用定制种植体进一步将LOS显著减少至1.6天。植入定制装置的患者在24小时内出院的比例(66%)明显高于OTS组(30%)。使用定制植入物治疗的患者比使用OTS植入物治疗的患者更常出院回家(97%对80%),并且在6-8周(114°对101°)和平均16个月(122°对114°)的活动范围都比使用OTS植入物治疗的患者高。在平均28个月的随访中,定制组进行了1次假体翻修(由于患者跌倒导致胫骨骨折)。对于OTS组,有1例种植体翻修(晚期感染)和1例poly交换(由于不稳定)。根据我们的分析,我们观察到定制设备对患者预后和医院指标的积极影响,因此我们得出结论,在“快速通道”设置中,植入物的选择是TKA的重要因素。
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引用次数: 6
Can We Improve Screening Costs in Asymptomatic Metal on Metal Total Hip Arthroplasties? 我们能提高无症状金属对金属全髋关节炎的筛查成本吗?
Pub Date : 2019-04-08 DOI: 10.15438/RR.9.1.214
J. R. Martin, Jesse E. Otero, B. Springer, W. Griffin
Introduction: Metal on Metal (MoM) total hip arthroplasty (THA) has been largely abandoned in the United States secondary to high failure rates. Many of the failures are attributed to adverse local tissue reactions (ALTR). Therefore, patients that have a MoM THA are routinely screened by checking serum metal ion levels every two years, as was recommended by the FDA. However, there is limited data on the costs of current screening protocols. Materials and Methods: 318 consecutive patients who underwent a MoM THA at a single institution were retrospectively enrolled. The average follow-up was 8.2 years. Clinical data, metal ion levels, revision and reoperation rates were prospectively collected. The costs of clinical screening for this patient population was calculated and compared to the cost of an annual screening protocol. Results: 12 patients had either an elevated Co or Cr level (>4.5 ppb). Eight patients were revised secondary to ALTR. The total cost of screening during the study was $612,250. Additionally, if annual screening had been performed, total screening costs would be approximately $1,719,200. Discussion: Eight patients in the following study were revised secondary to ALTR with a total cost of screening of $612,500. These costs are substantially less than the cost of annual screening ($1,719,200). Due to the considerable costs of screening asymptomatic MoM THA patients, we recommend both optimizing the frequency of screening and evaluating the specific risk of the implant being screened. 
引言:由于失败率高,金属对金属(MoM)全髋关节置换术(THA)在美国已被大量放弃。许多失败归因于局部组织不良反应(ALTR)。因此,按照美国食品药品监督管理局的建议,患有MoM THA的患者每两年通过检查血清金属离子水平进行常规筛查。然而,关于目前筛查方案的成本数据有限。材料和方法:回顾性纳入318例在单一机构接受MoM THA的连续患者。平均随访8.2年。前瞻性收集临床数据、金属离子水平、翻修和再手术率。计算了该患者群体的临床筛查成本,并将其与年度筛查方案的成本进行了比较。结果:12例患者的Co或Cr水平升高(>4.5ppb)。对8例患者进行ALTR二次修正。研究期间筛查的总费用为612250美元。此外,如果每年进行一次筛查,筛查费用总额约为1719200美元。讨论:以下研究中的8名患者被修正为ALTR二级患者,筛查总成本为612500美元。这些费用大大低于每年筛查的费用(1719200美元)。由于筛查无症状MoM-THA患者的成本相当高,我们建议优化筛查频率并评估植入物筛查的具体风险。
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引用次数: 0
Dual Antibiotic Therapy with Vancomycin and Cefazolin for Surgical Prophylaxis in Total Knee Arthroplasty 万古霉素和头孢唑林联合抗生素治疗全膝关节置换术预防手术
Pub Date : 2018-12-31 DOI: 10.15438/RR.8.2.212
A. Cohen-Rosenblum, M. Crutcher, J. Gui, W. Novicoff, Stephen J. Nelson, J. Browne
Background: Perioperative administration of intravenous antibiotics is a routine part of total knee arthroplasty.  Antibiotic selection is a matter of controversy, and the potential risks and benefits associated with each antibiotic selection need to be considered.  The objective of this study is to examine the effects of routine dual antibiotic prophylaxis with both cefazolin and vancomycin on infection and renal failure after primary total knee arthroplasty (TKA) compared with cefazolin alone.Methods: We performed a retrospective review of primary TKA patients for two years before and two years after routine dual antibiotic prophylaxis was implemented at our institution. 1502 patients were included (567 cefazolin-only and 935 dual prophylaxis).  Results: 2 patients (0.4%) in the cefazolin-only group had a deep surgical site infection, compared with 13 patients (1.4%) in the dual prophylaxis group (p=0.06). 46 patients (8.1%) in the cefazolin-only group had postoperative renal failure, compared with 36 patients (3.9%) in the dual prophylaxis group (p=0.0006).Discussion and Conclusion: Our results did not support the routine use of vancomycin in primary total joint arthroplasty to decrease periprosthetic joint infection. However, we also did not see any clear harm due to renal failure in the routine use of dual antibiotic prophylaxis. 
背景:围手术期静脉注射抗生素是全膝关节置换术的常规部分。抗生素的选择是一个有争议的问题,需要考虑每种抗生素选择的潜在风险和益处。本研究的目的是与单独使用头孢唑林相比,检查常规双抗生素预防用头孢唑林和万古霉素对初次全膝关节置换术(TKA)后感染和肾衰竭的影响。方法:我们对原发性TKA患者在我们机构实施常规双抗生素预防之前和之后的两年进行了回顾性审查。纳入1502名患者(567名仅头孢唑林,935名双重预防)。结果:仅使用头孢唑林组有2例(0.4%)发生深部手术部位感染,而双重预防组有13例(1.4%)发生(p=0.06)。仅使用头孢唑林组有46例(8.1%)发生术后肾功能衰竭,与双重预防组的36名患者(3.9%)相比(p=0.0006)。讨论和结论:我们的结果不支持在初次全关节置换术中常规使用万古霉素来减少假体周围关节感染。然而,在常规使用双抗生素预防中,我们也没有发现任何明显的肾衰竭危害。
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引用次数: 2
Coronal Alignment in TKA: Traditional Principles Versus New Concepts TKA中的日冕对齐:传统原则与新概念
Pub Date : 2018-12-31 DOI: 10.15438/rr.8.2.213
T. Parisi, J. Jennings, D. Dennis
Background: Up to 20% of total knee arthroplasty (TKA) patients are not satisfied with their outcome, and coronal alignment is considered an important variable in attaining a well-functioning TKA. Neutral mechanical alignment is not necessarily the anatomic norm and has led some surgeons to advocate a shift in defining and attaining the optimal coronal component alignment. Our aim was to review the different coronal alignment paradigms of TKA and summarize the historical and contemporary outcomes of different alignment techniques.Methods: A systematic review was performed in March 2017 via PubMed using the search terms: coronal alignment, kinematic alignment, and total knee replacement using Boolean “and” in-between terms. Relevant results were then reviewed, analyzed and summarized Conclusions: Early clinical outcomes of kinematically aligned TKAs are promising, but long-term clinical results are unknown. Clinical, laboratory, and retrieval studies suggest that mechanical varus in TKA, especially involving the tibial component, may result in earlier failure. Kinematic alignment with boundaries may be an optimal strategy for patients with pre-operative constitutional varus or congenital tibia vara.
背景:高达20%的全膝关节置换术(TKA)患者对其结果不满意,冠状位对齐被认为是获得功能良好的TKA的一个重要变量。中性机械对准不一定是解剖学规范,并导致一些外科医生主张在定义和实现最佳冠状组件对准方面进行转变。我们的目的是回顾TKA的不同冠状排列模式,并总结不同排列技术的历史和当代结果。方法:2017年3月,通过PubMed进行了一项系统综述,检索词为:冠状位对齐、运动学对齐和全膝关节置换术,检索词之间使用布尔“和”。随后对相关结果进行了回顾、分析和总结。结论:运动学对准TKA的早期临床结果是有希望的,但长期临床结果尚不清楚。临床、实验室和检索研究表明,TKA的机械性内翻,尤其是涉及胫骨部件的内翻,可能导致早期失败。对于术前宪法性内翻或先天性胫骨内翻的患者来说,与边界的运动对齐可能是一种最佳策略。
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引用次数: 6
Is Utilizing a Modular Stemmed Tibial Component in Obese Patients Undergoing Primary Total Knee Replacement Cost-Effective? 在接受初次全膝关节置换术的肥胖患者中使用模块化固定胫骨组件是否经济有效?
Pub Date : 2018-12-31 DOI: 10.15438/RR.8.2.215
J. R. Martin, Jesse E. Otero, W. B. Beaver, B. Springer, W. Griffin
Introduction: There has been recent enthusiasm for the use of modular stemmed tibial components in obese (BMI ≥35kg/m2) patients undergoing primary total knee arthroplasty (TKA). This has been mainly driven by studies demonstrating statistically significant increases in the rates of aseptic tibial loosening (ATL) in this patient population. However, to our knowledge, no study has specifically evaluated the cost effectiveness of this current recommendation.Methods: The following study was performed utilizing previously obtained data on the incidence of ATL in obese patients undergoing primary TKA. This data was then utilized to create a cost calculator that can evaluate the price point at which the use of a stemmed tibial component in all obese patients would be less than or equal to the costs of revision surgery if a stemmed implant was not utilized.Results: Utilizing historical data with a revision rate of 4% for aseptic loosening of the tibia on obese patients, a cost calculator was developed. The cost calculator requires the input of expected or known incidence of ATL utilizing a stem extension and the expected or known costs of revision for ATL.Conclusion: The following cost calculator quickly determines a price point at which the use of a tibial stem offsets the costs of revision surgery. While this study may not provide an exact cost-effectiveness of modular stem fixation due to model limitations, it will hopefully initiate the discussion for providing more cost-effective individualized care for this patient population.
引言:最近,在接受初次全膝关节置换术(TKA)的肥胖(BMI≥35kg/m2)患者中,人们热衷于使用模块化胫骨干假体。这主要是由于研究表明,该患者群体中无菌性胫骨松动(ATL)的发生率在统计学上显著增加。然而,据我们所知,没有任何研究专门评估当前建议的成本效益。方法:利用先前获得的关于接受原发性TKA的肥胖患者ATL发病率的数据进行以下研究。然后利用这些数据创建一个成本计算器,该计算器可以评估在所有肥胖患者中使用带茎胫骨组件的价格点,如果不使用带茎植入物,该价格点将小于或等于翻修手术的成本。结果:利用肥胖患者胫骨无菌性松动的修订率为4%的历史数据,开发了一个成本计算器。成本计算器需要输入预期或已知的利用柄延长的ATL发生率以及预期或已知ATL翻修成本。结论:以下成本计算器可以快速确定使用胫骨柄抵消翻修手术成本的价格点。虽然由于模型的限制,这项研究可能无法提供模块化干细胞固定的确切成本效益,但它有望为该患者群体提供更具成本效益的个性化护理展开讨论。
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引用次数: 1
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Reconstructive Review
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