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Design and simulation of a resonant nanoring-based two-dimensional photonic crystal biosensor for cancer cell detection 基于共振纳米oring的二维光子晶体生物传感器在癌细胞检测中的设计与仿真
Q3 Physics and Astronomy Pub Date : 2024-06-03 DOI: 10.1016/j.rio.2024.100701
Farsad Heidari, Ahvan Sharifi

This article introduces a novel two-dimensional photonic crystal biosensor designed for the detection of various cancer cell types and the verification of associated parameters. The proposed structure features a circular resonator nanoring with a sensing region at its center, facilitating the connection with cancer cells. The sensor has been tested with a diverse range of cancer cell types including skin, cervical, blood, adrenal, and two subtypes of breast cancer cells (Sort 1 and Sort 2). All outputs of the structure were studied at two different wavelengths and its parameters were analyzed separately. The best quality factor obtained for normal and abnormal cells of the target structure is 13,353 and 3053, respectively. Due to its high-quality factor and high FOM and low DL, this sensor has an acceptable sensitivity of 214.28(nm/RIU). FOM and DL in this sensor are equal to 172.35(RIU−1) and 5.80 × 10−4(RIU), respectively. The resonant wavelength shift of this structure is a relatively good value due to the coupling distance between the input wave and the resonator nanoring.

本文介绍了一种新型二维光子晶体生物传感器,设计用于检测各种癌症细胞类型并验证相关参数。所提出的结构具有一个圆形谐振器纳米环,其中心有一个传感区域,便于与癌细胞连接。该传感器已在多种癌细胞类型中进行了测试,包括皮肤癌、宫颈癌、血癌、肾上腺癌和两种亚型乳腺癌细胞(Sort 1 和 Sort 2)。在两种不同波长下对该结构的所有输出进行了研究,并分别对其参数进行了分析。目标结构的正常细胞和异常细胞的最佳质量因子分别为 13 353 和 3053。由于其高质量系数、高 FOM 和低 DL,该传感器的灵敏度达到了可接受的 214.28(nm/RIU)。该传感器的 FOM 和 DL 分别等于 172.35(RIU-1) 和 5.80 × 10-4(RIU)。由于输入波与谐振纳米之间的耦合距离,该结构的谐振波长偏移值相对较好。
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引用次数: 0
Design of energy, cost-efficient binary to gray code converter with temperature and stability analysis 设计高能效、低成本的二进制灰码转换器,并进行温度和稳定性分析
Q3 Physics and Astronomy Pub Date : 2024-06-03 DOI: 10.1016/j.rio.2024.100712
Patthi Aruna, Gurumurthy Komanapalli

The Quantum Dot Cellular Automata (QCA) is an emerging quantum electronics technology in which quantum cells are the fundamental building blocks. In this work, a Binary to Gray (BTG) code converter design is proposed and implemented using the QCA Designer Tool. This code converter design requires fewer cells than earlier designs and also increases the converter’s implementation bit size to five. The primary objective of this proposal is to introduce a BTG code converter design that excels in temperature stability and energy efficiency. The cell count in the proposed converter design for two-bit, three-bit, and four-bit is decreased by 68.55 %, 66.52 %, and 67.77 %, respectively and the overall area improved by 46.15 %, 52.17 %, and 57.58 % for 2- bit,3-bit and 4-bit, respectively by considering a latency of 0.75. The five-bit BTG has an area of 0.20 µm2 with a cell count of 141 and a latency of 0.75. To validate the functionality of the proposed design, extensive simulations were carried out using the QCA Designer tool, QCA DesignerE tool, and QCA Pro tool respectively.

量子点蜂窝自动机(QCA)是一种新兴的量子电子技术,其中量子单元是基本的构建模块。在这项工作中,我们提出了一种二进制到灰度(BTG)代码转换器设计,并使用 QCA 设计工具进行了实现。与之前的设计相比,这种代码转换器设计所需的单元更少,同时还将转换器的实现位尺寸增加到了五个。本提案的主要目的是引入一种 BTG 代码转换器设计,该设计在温度稳定性和能效方面表现出色。考虑到 0.75 的延迟,所提出的转换器设计中,2 位、3 位和 4 位的单元数分别减少了 68.55%、66.52% 和 67.77%,2 位、3 位和 4 位的整体面积分别增加了 46.15%、52.17% 和 57.58%。五位 BTG 的面积为 0.20 µm2,单元数为 141,延迟为 0.75。为了验证拟议设计的功能,我们分别使用 QCA Designer 工具、QCA DesignerE 工具和 QCA Pro 工具进行了大量仿真。
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引用次数: 0
Fault-tolerant quantum-dot cellular automata linear feedback shift register for nano communication applications 用于纳米通信应用的容错量子点蜂窝自动机线性反馈移位寄存器
Q3 Physics and Astronomy Pub Date : 2024-06-01 DOI: 10.1016/j.rio.2024.100705
Birinderjit Singh Kalyan , Balwinder Singh

There has been remarkable research carried out on Nano-electronics where Quantum dot Cellular automata appearing as the next generation computing regimes. The QCA-based circuits are used in the quantum computational hardware to represents the quantum computations and integrated in the Nano Communication system. The research is carried out on various QCA based designs. The purpose of this paper is to design the novel 5-input majority gate which is fault tolerant and simulated under various defects. The kink energy of the proposed cell is carried out and for verification of its functionality physical proof is provided, which demonstrates the redundant version of the proposed design. The QCA cell defects were consciously implemented in the proposed structure to prove its novelty as the best candidate for the implementation of complex QCA circuits. The proposed structure is further utilized to construct the fault-tolerant XOR gate and fault-tolerant D flip flop. The fault-tolerant linear feedback shift register is constructed with 435 QCA cells which is prone to various defects described in this paper. The contribution of this paper is to construct the fault-tolerant circuit for the various Nano Communication application that utilizes the quantum computational algorithm.

量子点蜂窝自动机作为下一代计算机制,在纳米电子学领域开展了大量研究。基于 QCA 的电路被用于量子计算硬件,以表示量子计算,并集成到纳米通信系统中。对各种基于 QCA 的设计进行了研究。本文的目的是设计新型 5 输入多数门,它具有容错性,并在各种缺陷下进行了仿真。本文对所提出单元的扭结能量进行了分析,并提供了物理证明以验证其功能,证明了所提出设计的冗余版本。在拟议结构中有意识地实施了 QCA 单元缺陷,以证明其作为实施复杂 QCA 电路最佳候选方案的新颖性。我们进一步利用所提出的结构构建了容错 XOR 门和容错 D 触发器。容错线性反馈移位寄存器由 435 个 QCA 单元构成,容易出现本文所述的各种缺陷。本文的贡献在于为利用量子计算算法的各种纳米通信应用构建了容错电路。
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引用次数: 0
Hybrid model based on Fiber Bragg Grating and fluorescence intensities ratio for strain and temperature distinction 基于光纤布拉格光栅和荧光强度比的应变和温度区分混合模型
Q3 Physics and Astronomy Pub Date : 2024-06-01 DOI: 10.1016/j.rio.2024.100711
Hacen Khlaifi , Amira Zrelli , Tahar ezzedine

Fiber optic sensors, including Fiber Bragg Grating (FBG) networks, are widely used to monitor the structural health (SHM) of infrastructure such as buildings, bridges, and tunnels. However, their multiple sensitivities make it difficult to isolate the specific impacts of each measured parameter on FBG, compromising the accuracy of the data. To overcome this challenge, we propose an innovative approach that combines FBG with the principle of Fluorescence Intensity Ratio (FIR). This combination allows for a more accurate analysis of wavelength variations in FBG, thus facilitating the distinction between temperature and deformation impacts. Additionally, we are developing a matrix formula to accurately determine temperature and deformation from FBG and FIR data, thereby improving the reliability of structural monitoring. Our results demonstrate the effectiveness of this hybrid approach through experiments and simulations, highlighting its importance in optimizing the performance of SHM devices. By integrating these two technologies, our method allows for a better understanding of parameter variations, leading to more reliable and accurate monitoring of infrastructure structural health.

光纤传感器,包括光纤布拉格光栅(FBG)网络,被广泛用于监测建筑物、桥梁和隧道等基础设施的结构健康状况(SHM)。然而,由于光纤布拉格光栅具有多重敏感性,因此很难将每个测量参数对光纤布拉格光栅的具体影响隔离开来,从而影响了数据的准确性。为了克服这一难题,我们提出了一种将 FBG 与荧光强度比 (FIR) 原理相结合的创新方法。这种结合可以更准确地分析 FBG 的波长变化,从而便于区分温度和变形的影响。此外,我们正在开发一种矩阵公式,以便从 FBG 和 FIR 数据中准确确定温度和变形,从而提高结构监测的可靠性。我们的研究结果通过实验和模拟证明了这种混合方法的有效性,突出了它在优化 SHM 设备性能方面的重要性。通过整合这两种技术,我们的方法可以更好地理解参数变化,从而更可靠、更准确地监测基础设施的结构健康状况。
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引用次数: 0
A comprehensive study of ferroelectric, dielectric and optical properties of europium-doped SBD metal- organic framework 掺铕 SBD 金属有机框架铁电、介电和光学特性的综合研究
Q3 Physics and Astronomy Pub Date : 2024-06-01 DOI: 10.1016/j.rio.2024.100702
M. Ashraf Bujran, Asma Tahir, Basharat Want

The synthesis of Europium-doped Strontium based benzene dicarboxylate dimethylformamide metal–organic framework- Eu([Sr(μ-BDC)(DMF)])- with short form as Eu:SBD@MOF was carried out using the solvothermal method. The investigation involved characterization techniques such as X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), CHN analysis, and energy-dispersive X-ray (EDX) elemental analysis. The results confirmed the formation of metal–organic crystals in the framework. The XRD characterization shows good alignment with the simulated pattern of SBD. The experimental absorption spectrum displays distinct transitions of the Eu (III) ion alongside transitions of the ligands. Calculations of line strengths for all observed transitions have been conducted. The Judd-Ofelt theory has been employed to determine intensity parameters, transition probabilities, branching ratios, and radiative lifetimes for the Eu: SBD@MOF. These JO parameters further aid in calculating various excited state properties. When excited by ultraviolet and visible photons, the complex exhibits emission in the red region respectively. The crystal’s dielectric loss and dielectric constant were investigated for their frequency dependence. It was observed that by virtue of DMF, a molecule linked to the crystal, a synthesized MOF exhibits a good dielectric characteristic and when the temperature is raised to 558 K, the dielectric constant drops sharply as DMF molecule could not stand after this temperature. Further ferroelectric studies reveal that the Eu: SBD@MOF has maximum polarization of 0.27 C/cm2 which is greater than Rochelle salt and other MOF’s. Exploring the broadband dielectric response of metal–organic frameworks (MOFs) open up new avenues in research, potentially leading to innovative applications in smart optoelectronics, terahertz sensors, high-speed telecommunications, and microelectronics.

采用溶热法合成了掺铕锶的苯二甲酸二甲基甲酰胺金属有机框架--Eu([Sr(μ-BDC)(DMF)]),简称 Eu:SBD@MOF。研究涉及 X 射线衍射 (XRD)、傅立叶变换红外光谱 (FTIR)、扫描电子显微镜 (SEM)、CHN 分析和能量色散 X 射线 (EDX) 元素分析等表征技术。结果证实框架中形成了金属有机晶体。XRD 表征显示与 SBD 的模拟图案非常吻合。实验吸收光谱显示了 Eu (III) 离子的明显转变以及配体的转变。对所有观察到的跃迁进行了线强度计算。利用 Judd-Ofelt 理论确定了 Eu (III) 离子的强度参数、转变概率、分支比和辐射寿命:SBD@MOF。这些 JO 参数进一步帮助计算了各种激发态特性。在紫外线和可见光光子的激发下,该复合物分别在红色区域发光。对晶体的介电损耗和介电常数的频率依赖性进行了研究。结果表明,通过与晶体相连的分子 DMF,合成的 MOF 具有良好的介电特性,而当温度升高到 558 K 时,介电常数会急剧下降,因为 DMF 分子在此温度下无法存活。进一步的铁电研究表明,Eu:SBD@MOF 的最大极化值为 0.27 C/cm2,高于罗谢尔盐和其他 MOF。探索金属有机框架(MOFs)的宽带介电响应开辟了新的研究途径,有可能在智能光电子学、太赫兹传感器、高速通信和微电子学中实现创新应用。
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引用次数: 0
Temporal fiber-optic fluorescence study of FAD-NADH interactions in phantoms for potential applications in rapid liquid optical biopsy procedures 在模型中对 FAD-NADH 相互作用进行时态光纤荧光研究,有望应用于快速液体光学活检程序
Q3 Physics and Astronomy Pub Date : 2024-06-01 DOI: 10.1016/j.rio.2024.100707
Subitcha Jayasankar, Sujatha Narayanan Unni

Body fluids carry several biomarkers and genetic material that enable the detection of carcinogenesis and tumor metastasis. Owing to this, liquid biopsy is gaining importance and entering clinical practice as an adjunct modality to the current standard of practice in cancer detection. Liquid biopsy involving specimens such as urine is non-invasive and has biomarkers reflecting the tumor microenvironment. We investigate the normal and altered levels of cellular metabolic by-products in liquid phantoms and demonstrate their photon-induced excited-state interaction behaviour for potential diagnostic applications. Short-span temporal analysis of metabolic by-products FAD and NADH in liquid phantoms with fiber optic fluorescence spectroscopy is carried out. The mixed liquid phantom of FAD and NADH, showed excited state interactions that manifested as simultaneous inverse variation in the fluorescence emission from FAD and NADH in varying pH environments. Linear discriminant analysis of the time-varying integrated fluorescence intensity resulted in a 100% accuracy in classifying liquid samples between high and low metabolite concentrations. An extension of application of the experiment model for analysis of body fluids such as urine is also discussed.

体液中含有多种生物标记物和遗传物质,可用于检测癌变和肿瘤转移。因此,液体活检作为目前癌症检测标准的一种辅助方式,正日益受到重视并进入临床实践。涉及尿液等标本的液体活检是非侵入性的,具有反映肿瘤微环境的生物标记物。我们研究了液体模型中细胞代谢副产物的正常水平和变化水平,并展示了它们在光子诱导下的激发态相互作用行为,以用于潜在的诊断应用。我们利用光纤荧光光谱对液态模型中的代谢副产物 FAD 和 NADH 进行了短时分析。FAD 和 NADH 混合液体模型显示出激发态相互作用,表现为 FAD 和 NADH 在不同 pH 值环境下的荧光发射同时发生反向变化。通过对随时间变化的综合荧光强度进行线性判别分析,对高浓度和低浓度代谢物液体样本进行分类的准确率达到了 100%。此外,还讨论了实验模型在尿液等体液分析中的扩展应用。
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引用次数: 0
Second-harmonic generation of ultrashort pulses in refractive index linearly modulating quantum dot structure 折射率线性调制量子点结构中超短脉冲的二次谐波生成
Q3 Physics and Astronomy Pub Date : 2024-06-01 DOI: 10.1016/j.rio.2024.100706
Hakeem H. Al–Ameri , Muwaffaq Abdullah , Amin H. Al-Khursan

While other works use segments of nonlinear crystal to compensate for walk-off, this work utilizes a quantum dot (QD) nanostructure for such compensation. Such nanocrystal structures allow two benefits: the high nonlinear susceptibility in these nanocrystals and the high surface density of QDs in the structure. Good results are obtained for pre-chirping and modulation parameters. The results are computed at 10 and 100 kV/cm applied electric fields. Compared to ordinary nonlinear crystals, the pulse width, intensity, and efficiency of the second harmonic (SH) pulse are all higher in QD nanocrystals, even with a low electric field applied. Higher applied fields give higher results.

其他研究利用非线性晶体片段对走偏进行补偿,而本研究则利用量子点(QD)纳米结构对走偏进行补偿。这种纳米晶体结构有两个优点:这些纳米晶体的非线性高感性和结构中量子点的高表面密度。预啁啾和调制参数获得了良好的结果。结果是在 10 和 100 kV/cm 的外加电场下计算得出的。与普通非线性晶体相比,即使施加的电场较低,QD 纳米晶体的脉冲宽度、强度和二次谐波(SH)脉冲的效率都较高。施加的电场越高,效果越好。
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引用次数: 0
Analysis and mitigation of stimulated Raman scattering effects in OTDR monitored optical link 分析和缓解 OTDR 监测光链路中的受激拉曼散射效应
Q3 Physics and Astronomy Pub Date : 2024-05-29 DOI: 10.1016/j.rio.2024.100699
A.H. Hussein , S.B.A. Anas , M.S. Ghazali , R. Amran , S. Yaakob , M.H.A. Bakar , K. Khairi , A. Ahmad , N.A. Ngah , S.Z. Muhd-Yassin , D.C. Tee , Y.I. Go

The use of both traffic and optical time-domain reflectometer (OTDR) in active fiber monitoring will affect the dynamic range of the OTDR due to backscattered stimulated Raman scattering (SRS). In this paper, a simulation model and hardware experiment are proposed to investigate and mitigate the effects of a backscattered SRS signal on OTDR active fiber monitoring. A basic OTDR active fiber monitoring system based on non-amplified and amplified links was developed, where the effects of SRS backscattered noise, amplification noise, and power depletion were observed. The obtained simulation results indicated that the highest backscattered SRS was contributed by the booster amplifier link configuration, where the amplification of the OTDR signal increased drastically when the signal input power reached 10 dBm. The simulation setup was also used to mitigate the backscattered SRS by placing a chirped fiber Bragg grating (CFBG) at the OTDR to allow only the 1650 nm OTDR signal to be received by the OTDR, leaving other unwanted signals or noise behind. This mitigation successfully reduced other backscattered signals by approximately 4 dB. A proof-of-concept hardware experiment was conducted to test the feasibility of the proposed technique, and the result showed that the distortion in the trace was decreased and the OTDR penalty was also reduced to 0.41 dB.

在有源光纤监测中同时使用流量和光时域反射仪(OTDR)会因背向散射受激拉曼散射(SRS)而影响 OTDR 的动态范围。本文提出了一种仿真模型和硬件实验来研究和减轻背向散射 SRS 信号对 OTDR 有源光纤监测的影响。开发了一个基于非放大和放大链路的基本 OTDR 有源光纤监测系统,观察了 SRS 后向散射噪声、放大噪声和功率损耗的影响。模拟结果表明,增压放大器链路配置产生的 SRS 后向散射最高,当信号输入功率达到 10 dBm 时,OTDR 信号的放大率急剧增加。模拟装置还用于通过在 OTDR 上放置啁啾光纤布拉格光栅 (CFBG),使 OTDR 只接收 1650 nm 的 OTDR 信号,而不接收其他不需要的信号或噪声,从而减轻后向散射 SRS。这一缓解措施成功地将其他反向散射信号降低了约 4 分贝。为了测试所提技术的可行性,我们进行了一次概念验证硬件实验,结果表明,迹线失真减少了,OTDR 惩罚也降低到 0.41 dB。
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引用次数: 0
Green synthesis of zinc oxide magnetic nanocomposite via zinc electroplating effluent: Its characterization and application as a photocatalyst 通过电镀锌废水绿色合成氧化锌磁性纳米复合材料:其特性及其作为光催化剂的应用
Q3 Physics and Astronomy Pub Date : 2024-05-26 DOI: 10.1016/j.rio.2024.100698
Amir Azizi , Marziyeh Kazemi

This study considered the green preparation, characterization, and investigation of the photocatalytic properties of zinc oxide magnetic nanostructure using electroplating industry effluent in the preparation. In this regard, the prepared structure was characterized by several common methods, including XRD, UV–Vis, FT-IR, DLS and VSM, and some of its properties were determined, including magnetic property, optical activity and surface charge. After determining the structure and confirming the optical activity of the prepared particles, its efficiency as a catalyst was evaluated in the photodegradation of methylene blue (MB) dye. Based on the results of the characterization of the structure of the ZnFe2O4 compound, the energy gap was calculated to be 3.46 eV. The results of DLS and VSM analyses showed that the prepared nanocomposite has average size, surface charge and magnetic properties equal to 65.5 nm, +95.94 mV and 8 emu/g, respectively. After confirming the photocatalytic properties of the prepared magnetic nanocomposite, the best operating conditions for the photocatalytic degradation of MB were determined to be 0.5 g of the photocatalyst, concentration of 10 mg/L of MB, pH equal to 9 and 1 mL of hydrogen peroxide (30 %) in 60 min (80 % degradation).

本研究考虑了利用电镀工业废水制备氧化锌磁性纳米结构的绿色制备、表征和光催化性能研究。为此,研究人员采用 XRD、UV-Vis、FT-IR、DLS 和 VSM 等几种常用方法对所制备的结构进行了表征,并测定了其部分性质,包括磁性、光学活性和表面电荷。在确定了所制备颗粒的结构和光学活性后,评估了其作为催化剂在亚甲基蓝(MB)染料光降解中的效率。根据 ZnFe2O4 化合物的结构表征结果,计算出其能隙为 3.46 eV。DLS 和 VSM 分析结果表明,制备的纳米复合材料的平均尺寸、表面电荷和磁性能分别为 65.5 nm、+95.94 mV 和 8 emu/g。在确认所制备的磁性纳米复合材料的光催化特性后,确定光催化剂的最佳光催化降解 MB 的操作条件为:0.5 克光催化剂、浓度为 10 mg/L 的 MB、pH 值等于 9 和 1 mL 过氧化氢(30%),在 60 分钟内(降解率为 80%)。
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引用次数: 0
Polarization-resolved near-field characterization of coupling between a bus waveguide and a ring resonator 总线波导与环形谐振器之间耦合的偏振分辨近场特性分析
Q3 Physics and Astronomy Pub Date : 2024-05-25 DOI: 10.1016/j.rio.2024.100695
V.V. Tkachuk , J.P. Korterik , L. Chang , H.L. Offerhaus

Light propagation in Photonic integrated circuits (PICs), which can nowadays involve complex systems of light-guiding structures, is measured with different approaches(Nuzhdin et al., 2020, Lončar et al., 2002, Hopman et al., 2007, Morichetti et al., 2014, Sapienza et al., 2012, Vesseur et al., 2007). An interferometric polarization-sensitive measurement of the evanescent fields of these structures provides insight in the performance of the circuit detects possible malfunction with sub-wavelength precision(Engelen et al., 2007, Gersen et al., 2005, Barwick et al., 2009). We demonstrate a Near-field scanning optical microscopy (NSOM) measurement on coupled ring resonators that shows how the guided modes evolve as they propagate across the optical chip. Analysis of the measurements provides information about intensity distribution of the two polarization components (TE and TM) and their spatial confinement. The data validates our methodology and opens new possibilities for analysis of signal propagation in prototyping and optimization of integrated optical systems. Direct observation of polarization state of the guided modes allows for clear understanding of mode conversion in coupling systems.

如今,光子集成电路 (PIC) 中的光传播可能涉及复杂的光导结构系统,测量光传播的方法多种多样(Nuzhdin 等人,2020 年;Lončar 等人,2002 年;Hopman 等人,2007 年;Morichetti 等人,2014 年;Sapienza 等人,2012 年;Vesseur 等人,2007 年)。对这些结构的蒸发场进行干涉偏振敏感测量,可以深入了解电路的性能,以亚波长精度检测可能出现的故障(Engelen 等人,2007 年;Gersen 等人,2005 年;Barwick 等人,2009 年)。我们展示了对耦合环形谐振器的近场扫描光学显微镜(NSOM)测量,显示了引导模式在光学芯片上传播时的演变过程。对测量结果的分析提供了有关两个极化分量(TE 和 TM)的强度分布及其空间限制的信息。这些数据验证了我们的方法,并为集成光学系统原型设计和优化中的信号传播分析提供了新的可能性。通过直接观察引导模式的偏振状态,可以清楚地了解耦合系统中的模式转换。
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引用次数: 0
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