Pub Date : 2025-07-01DOI: 10.1016/j.pcad.2025.07.002
Wissam Mekary, Colby Shanafelt, Elsa Hebbo, Mikhael F. El-Chami
Leadless pacemakers offer several advantages over transvenous pacemakers. They mainly reduce lead and pocket related complications which result in a reduction of re-intervention and infection rates (Graphical abstract). However, leadless pacemakers are not without drawbacks. Implantation of leadless pacemakers present a higher risk of pericardial perforation compared to its transvenous counterpart. Also, the leadless pacing technology is relatively new, and little is known about the best approach to manage these devices at the time of an upgrade or when the battery is at end of life. A modular approach for leadless pacing is emerging as a logical way to minimize the amount of hardware in the heart while preserving the ability to upgrade a single chamber device to a dual chamber (Graphical abstract). This review aims to present an overview of the different leadless pacemakers, indications for implantation, guidance on extraction while highlighting the advances made in the field.
{"title":"Leadless pacing: Technology, techniques, and emerging options","authors":"Wissam Mekary, Colby Shanafelt, Elsa Hebbo, Mikhael F. El-Chami","doi":"10.1016/j.pcad.2025.07.002","DOIUrl":"10.1016/j.pcad.2025.07.002","url":null,"abstract":"<div><div>Leadless pacemakers offer several advantages over transvenous pacemakers. They mainly reduce lead and pocket related complications which result in a reduction of re-intervention and infection rates (Graphical abstract). However, leadless pacemakers are not without drawbacks. Implantation of leadless pacemakers present a higher risk of pericardial perforation compared to its transvenous counterpart. Also, the leadless pacing technology is relatively new, and little is known about the best approach to manage these devices at the time of an upgrade or when the battery is at end of life. A modular approach for leadless pacing is emerging as a logical way to minimize the amount of hardware in the heart while preserving the ability to upgrade a single chamber device to a dual chamber (Graphical abstract). This review aims to present an overview of the different leadless pacemakers, indications for implantation, guidance on extraction while highlighting the advances made in the field.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"91 ","pages":"Pages 103-112"},"PeriodicalIF":7.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1016/j.pcad.2025.07.006
Tyson S. Burnham , Ravi Ranjan , Klitos Konstantinidis , Benjamin A. Steinberg , T. Jared Bunch
Atrial Fibrillation, dementia, and obesity are prevalent and interconnected pathologic states with significant morbidity and mortality and increasing global incidence. This review examines the current literature regarding the known and hypothesized relationships between these three conditions, their risk factors, and treatment strategies. We aim to highlight a stepwise and potentially causative interplay between them. As all three states become increasingly common in clinical practice, a detailed understanding of their multifactorial and multimodal relationship becomes critical for effective multidisciplinary care. Appropriate treatment of each is likely to reduce the burden of all three.
{"title":"Fat, fib, and forgetfulness: The interplay between adiposity, atrial fibrillation, and dementia","authors":"Tyson S. Burnham , Ravi Ranjan , Klitos Konstantinidis , Benjamin A. Steinberg , T. Jared Bunch","doi":"10.1016/j.pcad.2025.07.006","DOIUrl":"10.1016/j.pcad.2025.07.006","url":null,"abstract":"<div><div>Atrial Fibrillation, dementia, and obesity are prevalent and interconnected pathologic states with significant morbidity and mortality and increasing global incidence. This review examines the current literature regarding the known and hypothesized relationships between these three conditions, their risk factors, and treatment strategies. We aim to highlight a stepwise and potentially causative interplay between them. As all three states become increasingly common in clinical practice, a detailed understanding of their multifactorial and multimodal relationship becomes critical for effective multidisciplinary care. Appropriate treatment of each is likely to reduce the burden of all three.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"91 ","pages":"Pages 10-17"},"PeriodicalIF":7.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144669223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1016/j.pcad.2025.04.006
Ioan Liuba, Jakub Sroubek, Pasquale Santangeli
Ventricular arrhythmias (VAs) are highly prevalent in patients with advanced heart failure (AHF), a condition characterized by severe signs and symptoms despite conventional HF therapy. The management of VAs in this setting remains challenging. Antiarrhythmic drug therapy options are limited and only amiodarone has demonstrated effectiveness in suppressing VA, albeit this agent is associated with a substantial risk of cardiac and noncardiac adverse effects. Catheter ablation is effective for the reduction of VAs in patients with AHF. Identification of patients at high risk for periprocedural hemodynamic decompensation has important implications in terms of procedural planning and improving patient safety and procedural outcomes. Herein, we review the current state of scientific evidence for the management of VA in patients with AHF.
{"title":"Management of ventricular tachycardia in patients with advanced heart failure","authors":"Ioan Liuba, Jakub Sroubek, Pasquale Santangeli","doi":"10.1016/j.pcad.2025.04.006","DOIUrl":"10.1016/j.pcad.2025.04.006","url":null,"abstract":"<div><div><span><span>Ventricular arrhythmias (VAs) are highly prevalent in patients with advanced heart failure (AHF), a condition characterized by severe </span>signs and symptoms<span><span> despite conventional HF therapy. The management of VAs in this setting remains challenging. Antiarrhythmic drug therapy options are limited and only </span>amiodarone<span> has demonstrated effectiveness in suppressing VA, albeit this agent is associated with a substantial risk of cardiac and noncardiac adverse effects<span>. Catheter ablation is effective for the reduction of VAs in patients with AHF. Identification of patients at high risk for periprocedural </span></span></span></span>hemodynamic<span> decompensation has important implications in terms of procedural planning and improving patient safety and procedural outcomes. Herein, we review the current state of scientific evidence for the management of VA in patients with AHF.</span></div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"91 ","pages":"Pages 90-102"},"PeriodicalIF":7.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1016/j.pcad.2025.06.002
Benjamin M. Moore, Thomas M. Roston, Zachary Laksman, Andrew D. Krahn
The inherited arrhythmia (IA) syndromes are a group of rare and complex conditions that may predispose individuals to ventricular arrhythmias and sudden cardiac death. Our understanding of the genetic architecture underlying these syndromes has evolved, with recent reappraisals of variant pathogenicity and quantification of polygenic influences. The IA population includes an increasing proportion of low-risk patients, often identified via familial screening; avoiding over-treatment in these patients is an important consideration. Conversely, high-risk patients have an expanding armamentarium of targeted therapeutic interventions available beyond the ICD, with many emerging novel therapies. Refined risk stratification in the intermediate risk group is critical, utilising novel risk factors, genotype and multiparametric risk scores. Artificial intelligence will almost certainly play a role in diagnosis and risk stratification moving forward. Durable phenotype correction with gene therapy (or precision ablation) is an ultimate goal. This review will focus on updates in pathophysiology, diagnosis, risk stratification and management of Brugada syndrome, long QT syndrome, catecholaminergic polymorphic ventricular tachycardia and arrhythmogenic right ventricular cardiomyopathy.
{"title":"Updates on inherited arrhythmia syndromes (Brugada syndrome, long QT syndrome, CPVT, ARVC)","authors":"Benjamin M. Moore, Thomas M. Roston, Zachary Laksman, Andrew D. Krahn","doi":"10.1016/j.pcad.2025.06.002","DOIUrl":"10.1016/j.pcad.2025.06.002","url":null,"abstract":"<div><div>The inherited arrhythmia (IA) syndromes are a group of rare and complex conditions that may predispose individuals to ventricular arrhythmias and sudden cardiac death. Our understanding of the genetic architecture underlying these syndromes has evolved, with recent reappraisals of variant pathogenicity and quantification of polygenic influences. The IA population includes an increasing proportion of low-risk patients, often identified via familial screening; avoiding over-treatment in these patients is an important consideration. Conversely, high-risk patients have an expanding armamentarium of targeted therapeutic interventions available beyond the ICD, with many emerging novel therapies. Refined risk stratification in the intermediate risk group is critical, utilising novel risk factors, genotype and multiparametric risk scores. Artificial intelligence will almost certainly play a role in diagnosis and risk stratification moving forward. Durable phenotype correction with gene therapy (or precision ablation) is an ultimate goal. This review will focus on updates in pathophysiology, diagnosis, risk stratification and management of Brugada syndrome, long QT syndrome, catecholaminergic polymorphic ventricular tachycardia and arrhythmogenic right ventricular cardiomyopathy.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"91 ","pages":"Pages 130-143"},"PeriodicalIF":7.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1016/j.pcad.2025.06.006
Srinath Yeshwant, Gaurav A. Upadhyay
The field of cardiac pacing has changed dramatically since the first pacemakers were implanted in the 1950s.1 Over the ensuing decades, advancements in pacing technology have yielded longer battery life, smaller devices, sturdier leads, and more sophisticated pacemaker programming. Cardiac resynchronization therapy (CRT) represented a significant revolution in pacing approach, with the goal of correcting interventricular dyssynchrony through biventricular pacing. More recently, conduction system pacing (CSP) has emerged as a means to deliver even more physiological activation through direct engagement of the conduction system. The enthusiasm for CSP, driven primarily by investigator-initiated studies, has led to a rapid evolution in our understanding of conduction system physiology and represents a contemporary paradigm shift in our approach to treating patients with bradyarrhythmias and heart failure. The goal of this review is to provide a brief overview of the progression of CSP over time and to highlight key gaps in our understanding that need to be resolved prior to moving forward (Graphical Abstract).
{"title":"The evolution of conduction system pacing and gaps in understanding","authors":"Srinath Yeshwant, Gaurav A. Upadhyay","doi":"10.1016/j.pcad.2025.06.006","DOIUrl":"10.1016/j.pcad.2025.06.006","url":null,"abstract":"<div><div>The field of cardiac pacing has changed dramatically since the first pacemakers were implanted in the 1950s.<span><span><sup>1</sup></span></span><span><span> Over the ensuing decades, advancements in pacing technology have yielded longer battery life, smaller devices, sturdier leads, and more sophisticated pacemaker programming. Cardiac resynchronization therapy (CRT) represented a significant revolution in pacing approach, with the goal of correcting interventricular dyssynchrony through biventricular pacing. More recently, conduction system pacing (CSP) has emerged as a means to deliver even more physiological activation through direct engagement of the conduction system. The enthusiasm for CSP, driven primarily by investigator-initiated studies, has led to a rapid evolution in our understanding of conduction system physiology and represents a contemporary paradigm shift in our approach to treating patients with </span>bradyarrhythmias and heart failure. The goal of this review is to provide a brief overview of the progression of CSP over time and to highlight key gaps in our understanding that need to be resolved prior to moving forward (Graphical Abstract).</span></div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"91 ","pages":"Pages 113-120"},"PeriodicalIF":7.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.pcad.2025.03.015
Ross Arena , Grenita Hall
What defines a group of individuals as part of a community is broadly interpreted and depends on the context of the group being categorized. For this review, community may be defined as “as a group of people with diverse characteristics who are linked by social ties, share common perspectives, and engage in joint action in geographical locations or settings”. A given community will possess unique cultural attributes, defined by the American Psychological Association as “the values, beliefs, language, rituals, traditions, and other behaviors that are passed from one generation to another within any social group”. Unhealthy lifestyle behaviors drive the unacceptably high incidence and prevalence of chronic disease in the United States. Despite well intentioned efforts, society appears to be failing at altering the trajectory of unhealthy lifestyle behaviors, from an individual to population level. Perhaps our oftentimes one size fits all approach to health behavior messaging and counseling is a critical shortcoming. The fact that being more physically active, not smoking and consuming a healthier diet is of great benefit to human physiology and therefore human health outcomes is clear. However, human health behaviors or decisions to make a change in behavior are not driven by physiology but rather a complexly interacting milieu of factors - cultural drivers unique to a community amongst them. Herein, we discuss several community settings where there are opportunities to promote a culture of health living. This review will focus on settings that embody the definitions of community and culture described previously.
{"title":"The culture of healthy living in communities","authors":"Ross Arena , Grenita Hall","doi":"10.1016/j.pcad.2025.03.015","DOIUrl":"10.1016/j.pcad.2025.03.015","url":null,"abstract":"<div><div>What defines a group of individuals as part of a community is broadly interpreted and depends on the context of the group being categorized. For this review, community may be defined as “as a group of people with diverse characteristics who are linked by social ties, share common perspectives, and engage in joint action in geographical locations or settings”. A given community will possess unique cultural attributes, defined by the American Psychological Association as “the values, beliefs, language, rituals, traditions, and other behaviors that are passed from one generation to another within any social group”. Unhealthy lifestyle behaviors drive the unacceptably high incidence and prevalence of chronic disease in the United States. Despite well intentioned efforts, society appears to be failing at altering the trajectory of unhealthy lifestyle behaviors, from an individual to population level. Perhaps our oftentimes one size fits all approach to health behavior messaging and counseling is a critical shortcoming. The fact that being more physically active, not smoking and consuming a healthier diet is of great benefit to human physiology and therefore human health outcomes is clear. However, human health behaviors or decisions to make a change in behavior are not driven by physiology but rather a complexly interacting milieu of factors - cultural drivers unique to a community amongst them. Herein, we discuss several community settings where there are opportunities to promote a culture of health living. This review will focus on settings that embody the definitions of community and culture described previously.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 32-37"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.pcad.2025.03.007
Frederick J. Zimmerman , Nicolaas P. Pronk
We introduce the concept of forcing factors, analogous to risk factors for population-wide health outcomes, that are attributes of the physical, social, legal, economic, or cultural environment that are common to all people in an identified population and that promote or inhibit particular outcomes of health, wellness, and well-being. Examples include laws governing food or tobacco marketing, the built environment, and climate change. Culture also functions as a forcing factor of health outcomes. In contrast to past explanations of adverse health outcomes that have relied on cultural attributes of a specific sub-population, we draw on work of John McKinlay to make the point that it is the shared culture of a country or a region that influences health outcomes. Culture itself operates in a particular cultural context.
{"title":"Socioeconomic milieu and culture: Forcing factors and the Most fundamental determinant of health","authors":"Frederick J. Zimmerman , Nicolaas P. Pronk","doi":"10.1016/j.pcad.2025.03.007","DOIUrl":"10.1016/j.pcad.2025.03.007","url":null,"abstract":"<div><div>We introduce the concept of forcing factors, analogous to risk factors for population-wide health outcomes, that are attributes of the physical, social, legal, economic, or cultural environment that are common to all people in an identified population and that promote or inhibit particular outcomes of health, wellness, and well-being. Examples include laws governing food or tobacco marketing, the built environment, and climate change. Culture also functions as a forcing factor of health outcomes. In contrast to past explanations of adverse health outcomes that have relied on cultural attributes of a specific sub-population, we draw on work of John McKinlay to make the point that it is the shared culture of a country or a region that influences health outcomes. Culture itself operates in a particular cultural context.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 62-70"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.pcad.2025.04.007
Jacek Kwiecinski , Kajetan Grodecki , Konrad Pieszko , Maciej Dabrowski , Zbigniew Chmielak , Wojciech Wojakowski , Julia Niemierko , Jadwiga Fijalkowska , Dariusz Jagielak , Philipp Ruile , Simon Schoechlin , Hesham Elzomor , Piotr Slomka , Adam Witkowski , Damini Dey
Prediction of outcomes following transcatheter aortic valve replacement (TAVR) is challenging. Considering that in aortic stenosis outcomes are governed by both valve degeneration and myocardial adverse remodeling, we aimed to evaluate machine-learning leveraging pre-procedural computed tomography (CT) for the prediction of 1-year mortality following TAVR.
The analysis included data of consecutive patients who underwent TAVR at a high-volume center between January 2017 and January 2022 and was externally validated on unseen data from 3 international sites. Machine learning by extreme gradient boosting was trained and tested using clinical variables, CT-derived volumetric measurements including myocardial mass, and quantitative fibrocalcific aortic valve characteristics measured using standardized software. The EuroScore II and a separate machine learning risk score based exclusively on baseline clinical characteristics served as comparators.
The derivation cohort included 631 consecutive patients (48 % men, 80 ± 8 years old, EuroSCORE II 6.5 [4.6–10.3] %). Machine learning was externally validated on data of 596 patients (48 % men, 81 ± 8 years old, EuroSCORE II 5.4 [4.7–8.1] %). In external validation, the machine learning prognostic risk score had an area under the receiver operator curve of 0.79 (0.74–0.84) which was superior to the EuroSCORE 0.59 (0.53–0.66), and the machine learning risk based on clinical data alone 0.64 (0.59–0.69), p < 0.001 for difference.
Machine-learning integrating clinical data and CT-derived imaging characteristics was found to predict 1-year all-cause mortality following TAVR significantly better than clinical variables or clinical risk scores alone; and can help identify patients at higher prognostic risk prior to the procedure.
经导管主动脉瓣置换术（TAVR）后的预后预测具有挑战性。考虑到主动脉瓣狭窄的结果由瓣膜退变和心肌不良重构共同决定，我们旨在评估利用术前计算机断层扫描（CT）预测TAVR术后1年死亡率的机器学习。分析包括2017年1月至2022年1月在一个大容量中心接受TAVR的连续患者的数据，并根据来自3个国际站点的未见数据进行外部验证。通过极端梯度增强的机器学习进行训练和测试，使用临床变量、ct衍生的容积测量（包括心肌质量）和使用标准化软件测量的定量纤维钙化主动脉瓣特征。EuroScore II和单独的基于基线临床特征的机器学习风险评分作为比较。衍生队列包括631例连续患者（48%男性，80±8岁，EuroSCORE II 6.5[4.6-10.3] %）。对596例患者（男性48%，81±8岁，EuroSCORE II 5.4[4.7-8.1] %）的数据进行机器学习外部验证。在外部验证中，机器学习预后风险评分在受试者操作曲线下的面积为0.79(0.74-0.84)，优于EuroSCORE的0.59(0.53-0.66)，而单独基于临床数据的机器学习风险为0.64 (0.59-0.69),p
{"title":"Preprocedural CT angiography and machine learning for mortality prediction after transcatheter aortic valve replacement","authors":"Jacek Kwiecinski , Kajetan Grodecki , Konrad Pieszko , Maciej Dabrowski , Zbigniew Chmielak , Wojciech Wojakowski , Julia Niemierko , Jadwiga Fijalkowska , Dariusz Jagielak , Philipp Ruile , Simon Schoechlin , Hesham Elzomor , Piotr Slomka , Adam Witkowski , Damini Dey","doi":"10.1016/j.pcad.2025.04.007","DOIUrl":"10.1016/j.pcad.2025.04.007","url":null,"abstract":"<div><div>Prediction of outcomes following transcatheter aortic valve replacement (TAVR) is challenging. Considering that in aortic stenosis outcomes are governed by both valve degeneration and myocardial adverse remodeling, we aimed to evaluate machine-learning leveraging pre-procedural computed tomography (CT) for the prediction of 1-year mortality following TAVR.</div><div>The analysis included data of consecutive patients who underwent TAVR at a high-volume center between January 2017 and January 2022 and was externally validated on unseen data from 3 international sites. Machine learning by extreme gradient boosting was trained and tested using clinical variables, CT-derived volumetric measurements including myocardial mass, and quantitative fibrocalcific aortic valve characteristics measured using standardized software. The EuroScore II and a separate machine learning risk score based exclusively on baseline clinical characteristics served as comparators.</div><div>The derivation cohort included 631 consecutive patients (48 % men, 80 ± 8 years old, EuroSCORE II 6.5 [4.6–10.3] %). Machine learning was externally validated on data of 596 patients (48 % men, 81 ± 8 years old, EuroSCORE II 5.4 [4.7–8.1] %). In external validation, the machine learning prognostic risk score had an area under the receiver operator curve of 0.79 (0.74–0.84) which was superior to the EuroSCORE 0.59 (0.53–0.66), and the machine learning risk based on clinical data alone 0.64 (0.59–0.69), <em>p</em> < 0.001 for difference.</div><div>Machine-learning integrating clinical data and CT-derived imaging characteristics was found to predict 1-year all-cause mortality following TAVR significantly better than clinical variables or clinical risk scores alone; and can help identify patients at higher prognostic risk prior to the procedure.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 119-128"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/S0033-0620(25)00093-3
{"title":"List of recent issues","authors":"","doi":"10.1016/S0033-0620(25)00093-3","DOIUrl":"10.1016/S0033-0620(25)00093-3","url":null,"abstract":"","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Page A4"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01DOI: 10.1016/j.pcad.2025.02.007
Richard Severin , Ross Arena
With chronic diseases increasingly prevalent in the United States (U.S.), healthcare providers are in a unique position to promote healthy living behaviors, such as physical activity (PA) and nutrition, to patients. However, many healthcare providers struggle with maintaining their own health, which negatively affects their ability to counsel patients effectively on these behaviors. This paper highlights the barriers healthcare providers face in adopting and promoting healthy behaviors, including individual habits, lack of training, and environmental factors within healthcare institutions. It also examines how these barriers, such as insufficient educational opportunities, inadequate work environments, and systemic obstacles like time constraints and reimbursement issues, hinder effective PA and nutritional counseling. The authors propose that improving the health of healthcare providers will enhance the quality of counseling they provide, ultimately benefiting patient care and population health.
随着慢性病在美国日益流行，医疗保健提供者在向患者推广健康生活行为（如体育锻炼和营养）方面具有独特的优势。然而，许多医疗服务提供者在维护自身健康方面却举步维艰，这对他们有效指导患者这些行为的能力产生了负面影响。本文强调了医疗服务提供者在采纳和推广健康行为时面临的障碍，包括个人习惯、缺乏培训以及医疗机构内的环境因素。本文还探讨了这些障碍（如教育机会不足、工作环境不佳以及时间限制和报销问题等系统性障碍）是如何阻碍有效的 PA 和营养咨询的。作者建议，改善医疗保健提供者的健康状况将提高他们提供的咨询服务的质量，最终有利于患者护理和人口健康。
{"title":"A culture of health promotion in healthcare: Can't pour from an empty cup","authors":"Richard Severin , Ross Arena","doi":"10.1016/j.pcad.2025.02.007","DOIUrl":"10.1016/j.pcad.2025.02.007","url":null,"abstract":"<div><div>With chronic diseases increasingly prevalent in the United States (U.S.), healthcare providers are in a unique position to promote healthy living behaviors, such as physical activity (PA) and nutrition, to patients. However, many healthcare providers struggle with maintaining their own health, which negatively affects their ability to counsel patients effectively on these behaviors. This paper highlights the barriers healthcare providers face in adopting and promoting healthy behaviors, including individual habits, lack of training, and environmental factors within healthcare institutions. It also examines how these barriers, such as insufficient educational opportunities, inadequate work environments, and systemic obstacles like time constraints and reimbursement issues, hinder effective PA and nutritional counseling. The authors propose that improving the health of healthcare providers will enhance the quality of counseling they provide, ultimately benefiting patient care and population health.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 45-50"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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