Progress in cardiovascular diseases最新文献

{"title":"Incremental benefits of combined inhibition of SGLT1 and SGLT2 with sotagliflozin","authors":"Ram D. Bhatt , Bertram Pitt , Ph. Gabriel Steg , Deepak L. Bhatt","doi":"10.1016/j.pcad.2025.04.004","DOIUrl":"10.1016/j.pcad.2025.04.004","url":null,"abstract":"","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 3-5"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating cardiovascular implementation science research within healthcare systems","authors":"Muhammad Shahzeb Khan ,&nbsp;Ahmed Mustafa Rashid ,&nbsp;Harriette G.C. Van Spall ,&nbsp;Stephen J. Greene ,&nbsp;Ankeet S. Bhatt ,&nbsp;Ambarish Pandey ,&nbsp;Neil Keshvani ,&nbsp;Robert J. Mentz ,&nbsp;Andrew P. Ambrosy ,&nbsp;J. Michael DiMaio ,&nbsp;Javed Butler","doi":"10.1016/j.pcad.2025.04.005","DOIUrl":"10.1016/j.pcad.2025.04.005","url":null,"abstract":"<div><div>Only 1 in 5 evidence-based interventions make it to routine clinical practice and the evidence generated from clinical research may take 17 years to be implemented. This represents a lost opportunity to improve clinical care in healthcare systems. Implementation science refers to the study of methods to promote the adoption and integration of evidence-based practices, interventions, and policies into real-world clinical settings to positively impact population health. Therefore, implementation roadmaps can be crucial for learning healthcare systems (LHS) to bridge the research-to-practice gap, particularly for cardiovascular disease which remains the leading cause of death in the United States. Implementation models exist, all of which require a thorough understanding of the key phases of implementation for effective healthcare system incorporation and optimization (pre-implementation, implementation, monitoring the implementation, evaluation, sustaining, and scaling-up or de-implementation). This review serves as a call-to-action for involvement of large-scale LHS for cardiovascular implementation science, and provides a roadmap by summarizing various implementation science models, highlighting key implementation phases and discussing successful initiatives to improve the process. We also assess challenges associated with implementation science and provide possible solutions to improve translation of evidence in real-world clinical settings.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 97-108"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A culture of health promotion in healthcare: Can't pour from an empty cup","authors":"Richard Severin ,&nbsp;Ross Arena","doi":"10.1016/j.pcad.2025.02.007","DOIUrl":"10.1016/j.pcad.2025.02.007","url":null,"abstract":"<div><div>With chronic diseases increasingly prevalent in the United States (U.S.), healthcare providers are in a unique position to promote healthy living behaviors, such as physical activity (PA) and nutrition, to patients. However, many healthcare providers struggle with maintaining their own health, which negatively affects their ability to counsel patients effectively on these behaviors. This paper highlights the barriers healthcare providers face in adopting and promoting healthy behaviors, including individual habits, lack of training, and environmental factors within healthcare institutions. It also examines how these barriers, such as insufficient educational opportunities, inadequate work environments, and systemic obstacles like time constraints and reimbursement issues, hinder effective PA and nutritional counseling. The authors propose that improving the health of healthcare providers will enhance the quality of counseling they provide, ultimately benefiting patient care and population health.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 45-50"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"List of recent issues","authors":"","doi":"10.1016/S0033-0620(25)00093-3","DOIUrl":"10.1016/S0033-0620(25)00093-3","url":null,"abstract":"","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Page A4"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CTA in roadmapping post-CABG evaluation","authors":"Ilana S. Golub ,&nbsp;Angela Misic ,&nbsp;Srikanth Krishnan ,&nbsp;Logan Hubbard ,&nbsp;Dhananjay Chatterjee ,&nbsp;Rosa Lopez ,&nbsp;Travis Benzing ,&nbsp;Sina Kianoush ,&nbsp;Keishi Ichikawa ,&nbsp;Jairo Aldana-Bitar ,&nbsp;Matthew J. Budoff","doi":"10.1016/j.pcad.2025.04.009","DOIUrl":"10.1016/j.pcad.2025.04.009","url":null,"abstract":"<div><div>Although coronary artery bypass grafting (CABG) outcomes are typically highly successful, outpatient evaluation of bypass grafts is an important step. Moreover, the return of myocardial ischemia and acute coronary syndrome (ACS) events after bypass is not uncommon. Whether due to failure of prior bypass grafts or progression of underlying arteriosclerosis in native coronaries, regularly evaluating if a patient requires intervention (and assessing graft patency vs. closure) is essential. Imaging via cardiac computed tomography angiography (CTA) offers a gold standard anatomical map to facilitate efficiency and accuracy in later invasive coronary angiography (ICA) or surgical re-CABG intervention.</div><div>This review discusses the utility of CTA as a safe pre and post CABG evaluation tool, in guiding outpatient evaluation of graft patency and roadmapping subsequent reintervention if needed. We seek to ameliorate clinical uncertainties and synthesize growing amounts of research, to help encourage a homogenous approach to post-CABG evaluation. This comprehensive review paper introduces the indications for bypass grafting surgery and transcatheter PCI approaches, details techniques and strategies for bypass surgery, discusses CTA in evaluating post-CABG graft patency, and consolidates research surrounding pre-reintervention CTA in post-CABG patients. Last, this review explores future directions in standardizing post-CABG evaluation guidelines.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 86-96"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultural influences on dietary choices","authors":"Sisitha Jayasinghe ,&nbsp;Nuala M. Byrne ,&nbsp;Andrew P. Hills","doi":"10.1016/j.pcad.2025.02.003","DOIUrl":"10.1016/j.pcad.2025.02.003","url":null,"abstract":"<div><div>Food choices and dietary behaviors are inherently complex and influenced by numerous interconnected factors including individual preferences such as taste, meal timing, and social interactions, alongside external elements like affordability, cultural norms, marketing, and policy environments. The physical contexts of food consumption - homes, schools, workplaces, and neighborhoods- further shape these behaviors, as do societal expectations and generational food literacy. Underpinning these dynamics are food systems, which are influenced by health, ethical, and sustainability considerations throughout the food production and consumption continuum. Cultural influences, encompassing traditions, rituals, and shared beliefs, play a pivotal role in shaping dietary practices. Distinctions between “cultural food” and “food culture” illustrate the deep integration of cuisine within identity and daily life. Historical events, globalization, and modernization have reshaped food traditions, leading to the adoption of new eating patterns and the erosion of others. Religion, socioeconomic status, and social networks also critically impact dietary behaviors, while contemporary challenges such as the nutrition transition and fast-food culture contribute to rising chronic disease burdens. Addressing these issues requires culturally tailored interventions and a focus on food environments, integrating modern tools like social media to promote healthier, community-oriented behaviors while recognizing the social and emotional roles of food.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 22-26"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An ecological framework for population health and well-being","authors":"Nicolaas P. Pronk ,&nbsp;Colin Woodard ,&nbsp;Frederick J. Zimmerman ,&nbsp;Ross Arena","doi":"10.1016/j.pcad.2025.03.013","DOIUrl":"10.1016/j.pcad.2025.03.013","url":null,"abstract":"<div><div>Social structures have become focal points in considering how to address the circumstances and conditions under which people live their lives. Yet, the many interactions among multiple factors that make up social and structural determinants are complex, interdependent, interactive, dynamic, and multilevel. This paper introduces an evidence-informed ecological framework that organizes drivers and feedback mechanisms collectively representing a generative force towards population health and well-being. The proposed ecological framework supports explanatory and exploratory considerations for prevention and management of population health and well-being issues. The framework explicitly includes a recognition that successful health and well-being outcomes are often dependent on the presence of social capital and healthy power dynamics.</div><div>Dominant cultural norm is positioned as an overarching driver in this framework because it shapes the political realities and power dynamics responsible for infrastructure as well as the habits and behaviors of people at both the individual and social levels.</div></div>","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 13-21"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular magnetic resonance in pulmonary hypertension: Keeping it simple","authors":"Daniel Lorenzatti ,&nbsp;Manish Motwani","doi":"10.1016/j.pcad.2025.04.010","DOIUrl":"10.1016/j.pcad.2025.04.010","url":null,"abstract":"","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 116-118"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment adherence patterns for patients with atherosclerotic cardiovascular disease: Patient and provider perspectives","authors":"Mary T. Imboden ,&nbsp;Kyle G. Jones ,&nbsp;Sarah E. Roth ,&nbsp;Roxanne Marsillo ,&nbsp;Laney K. Jones ,&nbsp;Bethany Kalich ,&nbsp;Eduard Sidelnikov ,&nbsp;Ty J. Gluckman ,&nbsp;Jennifer Rountree ,&nbsp;Eleni Wilson ,&nbsp;Staci J. Wendt","doi":"10.1016/j.pcad.2025.06.004","DOIUrl":"10.1016/j.pcad.2025.06.004","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of mortality, affecting more than 500 million individuals globally. National guidelines recommend lipid-lowering therapies (LLTs) as first line agents for both primary and secondary prevention of ASCVD. However, under-prescribing of pharmacologic LLTs and sub-optimal medication adherence remain common problems.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Aim&lt;/h3&gt;&lt;div&gt;This mixed-methods study aimed to identify patient and prescriber factors influencing adherence to LLTs.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Patients with an ASCVD diagnosis and treatment plan that included LLT were sampled from a large community health system serving seven states. A stratified random sample of 2500 patients was surveyed by mail, capturing barriers and facilitators to medication adherence using an adapted version of the Adherence Starts with Knowledge-12 (ASK-12) scale, achieving a 16.2 % response rate (406 patients). Twenty-three semi-structured interviews were conducted with a sample of patient survey respondents to further explore drivers of non-adherence. Eligible prescribers with experience treating patients with ASCVD were surveyed by email, resulting in a 3.3 % response rate (122 respondents). Survey data were analyzed descriptively and using regression models; interview data were analyzed thematically.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;While cohort patients were identified as having an ASCVD diagnosis and taking a LLT from their medical chart, only 16.8 % of respondents reported having an ASCVD diagnosis and 84.2 % reported taking LLTs. Patients taking medication reported a higher average number of health condition diagnoses compared to those not taking a medication (2.63 and 1.50, respectively). Of those taking medication, 55.7 % were identified as adherent. Non-adherent patients were more likely to report poor healthcare experiences and social determinants of health needs. Multivariable regression analysis revealed that patients were more likely to be adherent when they felt their healthcare provider always spent enough time with them and treated them with respect. Interview findings further emphasized the importance of healthcare experiences, convenience, and belief the treatment works as important factors to adherence. In contrast, prescribers perceived higher non-adherence rates, citing forgetfulness and medication inconvenience as the main barriers. However, only 10.0 % of responding prescribers reported using a tool to assess patients' medication adherence and only 42.6 % reported asking patients about changes to their medication regimens.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;A substantial proportion of patients reported adherence to their medications, with adherence being associated with positive healthcare experiences, self-reported health conditions, perceived effectiveness of the medication, and social determinants of health needs. Prescribers perceived relatively low adh","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 131-141"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the burden of acute myocardial infarction deaths associated with COVID-19 during the first five years of the pandemic","authors":"Giuseppe Lippi ,&nbsp;Carl J. Lavie ,&nbsp;Fabian Sanchis Gomar","doi":"10.1016/j.pcad.2025.02.004","DOIUrl":"10.1016/j.pcad.2025.02.004","url":null,"abstract":"","PeriodicalId":21156,"journal":{"name":"Progress in cardiovascular diseases","volume":"90 ","pages":"Pages 150-151"},"PeriodicalIF":5.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}