Pub Date : 2023-08-01DOI: 10.55453/rjmm.2023.126.4.9
Oana A Alexiu-Toma, M. Toma, M. Stavarachi, Alexandra V. Danciu, D. Cimponeriu, C. Constantin, R. Nica, N. Butoianu, S. Nica, Ileana Stoica
Different factors may be involved in the clinical heterogeneity of spinal muscular atrophy disease. The vitamin D receptor (VDR) might be a candidate gene for this disease. Our study aimed to assess the preferential transmission of VDR polymorphisms from parents to SMA children. We genotyped 261 subjects (87 SMA nuclear families) for VDR FokI, BsmI, ApaI, and TaqI polymorphisms. The transmission of the genetic marker was estimated with Plink and FBAT software. It detected a preferential transmission of the rs731236 and rs7975232 variants to SMA1 patients and of rs1544410 variants to SMA2 patients. The variants of rs2228570 were preferentially transmitted to parents of all SMA patients. Haplotype analysis identified that haplotypes C-C-G-A and T-A-A-G seem to be involved in the booth type of SMA whereas the impact of T-A-A-A seems to be limited only to SMA2. Strong linkage disequilibrium (LD) between rs7975232 and rs1544410 was detected in samples from parents. Even though we investigated a small number of nuclear families the results suggest a potential link between VDR polymorphisms and SMA disease.
{"title":"A Family-based Association Test of the VDR Gene in Proximal Spinal Muscular Atrophy","authors":"Oana A Alexiu-Toma, M. Toma, M. Stavarachi, Alexandra V. Danciu, D. Cimponeriu, C. Constantin, R. Nica, N. Butoianu, S. Nica, Ileana Stoica","doi":"10.55453/rjmm.2023.126.4.9","DOIUrl":"https://doi.org/10.55453/rjmm.2023.126.4.9","url":null,"abstract":"Different factors may be involved in the clinical heterogeneity of spinal muscular atrophy disease. The vitamin D receptor (VDR) might be a candidate gene for this disease. Our study aimed to assess the preferential transmission of VDR polymorphisms from parents to SMA children. We genotyped 261 subjects (87 SMA nuclear families) for VDR FokI, BsmI, ApaI, and TaqI polymorphisms. The transmission of the genetic marker was estimated with Plink and FBAT software. It detected a preferential transmission of the rs731236 and rs7975232 variants to SMA1 patients and of rs1544410 variants to SMA2 patients. The variants of rs2228570 were preferentially transmitted to parents of all SMA patients. Haplotype analysis identified that haplotypes C-C-G-A and T-A-A-G seem to be involved in the booth type of SMA whereas the impact of T-A-A-A seems to be limited only to SMA2. Strong linkage disequilibrium (LD) between rs7975232 and rs1544410 was detected in samples from parents. Even though we investigated a small number of nuclear families the results suggest a potential link between VDR polymorphisms and SMA disease.","PeriodicalId":21298,"journal":{"name":"Romanian Journal of Military Medicine","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42628551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-01DOI: 10.55453/rjmm.2023.126.4.22
M. Licu, C. G. Ionescu, M. Suciu, Sorin Păun
"Background: The prevalence of smoking among students is a growing concern, particularly among medical students. Being associated with stress, competitiveness, and various social influences, smoking can have detrimental effects on self-esteem and self-efficacy and may create a vicious cycle that may contribute to student’s well-being and academic performance outcomes. We aimed to investigate the relationship between self-esteem, self-efficacy, and smoking habits among medical students and their sociodemographic correlates. Methods: A cross-sectional study on 456 medical students was conducted via an online survey using structured questionnaires on socio-demographic characteristics, smoking habits, nicotine dependence, self-esteem, and self-efficacy. Results: The prevalence of smoking was 31.1% The scores of self-esteem and self-efficacy were positively correlated with smoking habits (W1=0.957, W2=0.975, P<0.05). Students presented rather low smoking addiction with male students having slightly higher scores than female students on self-esteem and self-efficacy, military students had higher self-esteem scores than civilians with physical activity having a positive correlation with non-smoking behavior. Conclusion: According to our results, selfesteem and self-efficacy were slightly positively correlated with smoking habits. Furthermore, there was no statistically significant association between other social factors and smoking. Our results may develop a theoretical basis for medical students’ psychological variables studying for further implementation of university educational programs and preventive interventions empowering students towards an overall better quality of life, addressing, among others, smoking behaviors."
{"title":"Self-esteem, Self-efficacy, and Smoking Prevalence: A Cross-sectional Study Among Military and Civilian Medical Students","authors":"M. Licu, C. G. Ionescu, M. Suciu, Sorin Păun","doi":"10.55453/rjmm.2023.126.4.22","DOIUrl":"https://doi.org/10.55453/rjmm.2023.126.4.22","url":null,"abstract":"\"Background: The prevalence of smoking among students is a growing concern, particularly among medical students. Being associated with stress, competitiveness, and various social influences, smoking can have detrimental effects on self-esteem and self-efficacy and may create a vicious cycle that may contribute to student’s well-being and academic performance outcomes. We aimed to investigate the relationship between self-esteem, self-efficacy, and smoking habits among medical students and their sociodemographic correlates. Methods: A cross-sectional study on 456 medical students was conducted via an online survey using structured questionnaires on socio-demographic characteristics, smoking habits, nicotine dependence, self-esteem, and self-efficacy. Results: The prevalence of smoking was 31.1% The scores of self-esteem and self-efficacy were positively correlated with smoking habits (W1=0.957, W2=0.975, P<0.05). Students presented rather low smoking addiction with male students having slightly higher scores than female students on self-esteem and self-efficacy, military students had higher self-esteem scores than civilians with physical activity having a positive correlation with non-smoking behavior. Conclusion: According to our results, selfesteem and self-efficacy were slightly positively correlated with smoking habits. Furthermore, there was no statistically significant association between other social factors and smoking. Our results may develop a theoretical basis for medical students’ psychological variables studying for further implementation of university educational programs and preventive interventions empowering students towards an overall better quality of life, addressing, among others, smoking behaviors.\"","PeriodicalId":21298,"journal":{"name":"Romanian Journal of Military Medicine","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45392889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-01DOI: 10.55453/rjmm.2023.126.4.11
A. Enache, L. Eftimie, A. Graur, Remus R. Glogojeanu, Adina Geambașu, O. Voinea, D. Costache, R. Costache, M. Sajin, G. Stanciu
Objective: The study subject approaches a topic of cerebral pathology, namely the development of a pathological diagnosis that is as accurate as possible for the cerebral tumors and the metastases, using a new method that complements the optical microscopic examination and immunohistochemistry to correctly diagnose cerebral malignancies. Methods: Two-photon excitation (TPE) microscopy techniques are non-linear optical imaging methods that are gaining momentum in the investigation of fixed tissue sections, fresh tissue, or even for in vivo experiments. This method can be used for offering complementary information on the tissue architecture. We argue that using non-linear optical microscopy (which includes TPE microscopy) images collected on this category of brain tissue samples, can facilitate the interpretation of brain tumors and metastases, thus it is a solution worthy to explore. Scanning large areas of the lesions is important to avoid false-negative diagnoses because lesions are often non-uniform. Finding potential invasion sites is also restricted when using a narrow field-of-view imaging method. Results: Our study demonstrated that TPE microscopy can detect specific cellular features of cerebral tumors and metastases in good correlation with histopathological results. This approach can improve the accuracy of the cerebral tumors diagnosis and possibly other neoplasms. Conclusion: TPE microscopy is very important for future research because it could prevent the false or inadequate diagnosis of specific lesions and differentiate a primary tumor from a metastasis. The significance of the findings is attributable to cross-disciplinary cooperation and the constant use of a working standard across all of the experiments in this study.
{"title":"Assessment of Cerebral Tumors and Metastases by Two-Photon Excitation Microscopy","authors":"A. Enache, L. Eftimie, A. Graur, Remus R. Glogojeanu, Adina Geambașu, O. Voinea, D. Costache, R. Costache, M. Sajin, G. Stanciu","doi":"10.55453/rjmm.2023.126.4.11","DOIUrl":"https://doi.org/10.55453/rjmm.2023.126.4.11","url":null,"abstract":"Objective: The study subject approaches a topic of cerebral pathology, namely the development of a pathological diagnosis that is as accurate as possible for the cerebral tumors and the metastases, using a new method that complements the optical microscopic examination and immunohistochemistry to correctly diagnose cerebral malignancies. Methods: Two-photon excitation (TPE) microscopy techniques are non-linear optical imaging methods that are gaining momentum in the investigation of fixed tissue sections, fresh tissue, or even for in vivo experiments. This method can be used for offering complementary information on the tissue architecture. We argue that using non-linear optical microscopy (which includes TPE microscopy) images collected on this category of brain tissue samples, can facilitate the interpretation of brain tumors and metastases, thus it is a solution worthy to explore. Scanning large areas of the lesions is important to avoid false-negative diagnoses because lesions are often non-uniform. Finding potential invasion sites is also restricted when using a narrow field-of-view imaging method. Results: Our study demonstrated that TPE microscopy can detect specific cellular features of cerebral tumors and metastases in good correlation with histopathological results. This approach can improve the accuracy of the cerebral tumors diagnosis and possibly other neoplasms. Conclusion: TPE microscopy is very important for future research because it could prevent the false or inadequate diagnosis of specific lesions and differentiate a primary tumor from a metastasis. The significance of the findings is attributable to cross-disciplinary cooperation and the constant use of a working standard across all of the experiments in this study.","PeriodicalId":21298,"journal":{"name":"Romanian Journal of Military Medicine","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49267327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-01DOI: 10.55453/rjmm.2023.126.4.10
C. Nicolau, Bogdan Cormos, Luiza Enache, Adrian Tarta, R. Şipoş, A. Saftoiu
The evolution of society, the development of the Internet, and the increased need for medical services generated the emergence of telemedicine. The visual and auditory connection between the doctor and the patient allowed good communication, but the limitation of the clinical examination remained a problem. Tele-echography complements tele-consults and brings valuable information in many specialties. Our study is conducted on data obtained by organizing the first network of telemedicine with tele-echography in the country. The ultrasound examinations targeted only the abdomen, but the structure also allows teleechocardiography as well as the extension to other services at distance. The purpose of the study is to objectively assess the ability of tele-echography to complete the teleconsultation with information on which we can rely. The national tele-echography network was created by distributing 40 tele-echographs in the country, one in each county, in the family doctors' offices. The obtained data were analyzed statistically. The study shows that tele-echography can be performed with very good accuracy in synchronous mode but low in asynchronous mode, which required re-examination or resumption of examination in the reference medical center. The widespread use of tele-echography associated with teleconsultations can have favorable consequences on the medical act, the quality of life of the patients and the doctors, and society by reducing pollution and urban agglomerations.
{"title":"First Romanian Tele-Echography Network – Preliminary Results","authors":"C. Nicolau, Bogdan Cormos, Luiza Enache, Adrian Tarta, R. Şipoş, A. Saftoiu","doi":"10.55453/rjmm.2023.126.4.10","DOIUrl":"https://doi.org/10.55453/rjmm.2023.126.4.10","url":null,"abstract":"The evolution of society, the development of the Internet, and the increased need for medical services generated the emergence of telemedicine. The visual and auditory connection between the doctor and the patient allowed good communication, but the limitation of the clinical examination remained a problem. Tele-echography complements tele-consults and brings valuable information in many specialties. Our study is conducted on data obtained by organizing the first network of telemedicine with tele-echography in the country. The ultrasound examinations targeted only the abdomen, but the structure also allows teleechocardiography as well as the extension to other services at distance. The purpose of the study is to objectively assess the ability of tele-echography to complete the teleconsultation with information on which we can rely. The national tele-echography network was created by distributing 40 tele-echographs in the country, one in each county, in the family doctors' offices. The obtained data were analyzed statistically. The study shows that tele-echography can be performed with very good accuracy in synchronous mode but low in asynchronous mode, which required re-examination or resumption of examination in the reference medical center. The widespread use of tele-echography associated with teleconsultations can have favorable consequences on the medical act, the quality of life of the patients and the doctors, and society by reducing pollution and urban agglomerations.","PeriodicalId":21298,"journal":{"name":"Romanian Journal of Military Medicine","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46067204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The highlighting of possible risk factors for urinary colonization in patients with obstructive urolithiasis that needed double J catheters implanted to preserve renal function. Methods: We performed a descriptive, retrospective study, carried out in the Urology Department of the Bucharest Central Military Hospital, between January 2020 and January 2022 and included 168 patients with urolithiasis who required the insertion of double J catheters. We studied the bacteriological profile, using both urine and JJ catheter samples. Results: We obtained a double J catheter colonization rate of 32% (54 patients) and 29% of urinary colonization (49 patients). The rate of urinary colonization is higher in patients with colonized ureteral catheters regardless of sex, age, and associated comorbidities. At the same time, we noticed an increased rate of urinary colonization in patients associated with diabetes, hypertension, and chronic kidney disease. Conclusions: The prevalence of urinary colonization in patients with double J catheters was 29%. The colonization of the JJ catheters, as well as the association with chronic diseases, such as diabetes, hypertension, and CKD (Chronic Kidney Disease), show an increased risk of urinary colonization.
{"title":"Survey the Effect of Educational Intervention Based on Mobile Short Message Service (SMS) on Self-Care in Patients with Type 2 Diabetes Referring to the Diabetes Clinic in Khorram Abad City","authors":"Elnaz Ashrafi, Farnoush Bazvandi, Fatemeh S. Izadkhah, Tahereh Dehdari, Bahare Izadi, Omid Safari, Morteza Mansourian","doi":"10.55453/rjmm.2023.126.4.5","DOIUrl":"https://doi.org/10.55453/rjmm.2023.126.4.5","url":null,"abstract":"Background: The highlighting of possible risk factors for urinary colonization in patients with obstructive urolithiasis that needed double J catheters implanted to preserve renal function. Methods: We performed a descriptive, retrospective study, carried out in the Urology Department of the Bucharest Central Military Hospital, between January 2020 and January 2022 and included 168 patients with urolithiasis who required the insertion of double J catheters. We studied the bacteriological profile, using both urine and JJ catheter samples. Results: We obtained a double J catheter colonization rate of 32% (54 patients) and 29% of urinary colonization (49 patients). The rate of urinary colonization is higher in patients with colonized ureteral catheters regardless of sex, age, and associated comorbidities. At the same time, we noticed an increased rate of urinary colonization in patients associated with diabetes, hypertension, and chronic kidney disease. Conclusions: The prevalence of urinary colonization in patients with double J catheters was 29%. The colonization of the JJ catheters, as well as the association with chronic diseases, such as diabetes, hypertension, and CKD (Chronic Kidney Disease), show an increased risk of urinary colonization.","PeriodicalId":21298,"journal":{"name":"Romanian Journal of Military Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135970338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-01DOI: 10.55453/rjmm.2023.126.4.16
F. Tamer, İ. Ozdemi̇r, A. Gulekon
": Chronic inflammation and immunosuppressive treatment may play a role in the etiopathogenesis of cancer in psoriasis patients. We wanted to evaluate the Papanicolaou smear (Pap smear) results of female patients with psoriasis which were performed for cervical cancer screening before the initiation of biological agent treatment. Between April 2019 and November 2021, Pap smear results of female patients with psoriasis were reviewed retrospectively. This study included 70 female psoriasis patients with a mean age of 48.41±11.62 years. 49 (70%) patients were biologically naive, whereas 21 (30%) patients previously received biological agents. Obscuring inflammation was reported in 33 (47.1%) patients. Atrophy, intermediate cell predominance, reactive cellular changes due to inflammation, and both atrophy and reactive cellular changes were detected in 15 (21.4%), 7 (10%), 3 (4.3%) patients, and 1 (1.4%) patient, respectively. No malignancy or intraepithelial lesion was observed in 69 (98.6%) patients, whereas atypical squamous cells of undetermined significance were reported in 1 (1.4%) patient. Infections such as bacterial vaginosis, candidiasis, and actinomycosis were detected in 13 (18.6%) patients. Pap smear tests should be performed in female psoriasis patients to detect premalignant lesions of the cervix before the initiation of biological agent treatment. Moreover, psoriasis treatment guidelines should be updated accordingly"
{"title":"Should Cervical Cancer Screening with Papanicolaou Smear be Recommended for Female Patients with Psoriasis before Biological Agent Treatment?","authors":"F. Tamer, İ. Ozdemi̇r, A. Gulekon","doi":"10.55453/rjmm.2023.126.4.16","DOIUrl":"https://doi.org/10.55453/rjmm.2023.126.4.16","url":null,"abstract":"\": Chronic inflammation and immunosuppressive treatment may play a role in the etiopathogenesis of cancer in psoriasis patients. We wanted to evaluate the Papanicolaou smear (Pap smear) results of female patients with psoriasis which were performed for cervical cancer screening before the initiation of biological agent treatment. Between April 2019 and November 2021, Pap smear results of female patients with psoriasis were reviewed retrospectively. This study included 70 female psoriasis patients with a mean age of 48.41±11.62 years. 49 (70%) patients were biologically naive, whereas 21 (30%) patients previously received biological agents. Obscuring inflammation was reported in 33 (47.1%) patients. Atrophy, intermediate cell predominance, reactive cellular changes due to inflammation, and both atrophy and reactive cellular changes were detected in 15 (21.4%), 7 (10%), 3 (4.3%) patients, and 1 (1.4%) patient, respectively. No malignancy or intraepithelial lesion was observed in 69 (98.6%) patients, whereas atypical squamous cells of undetermined significance were reported in 1 (1.4%) patient. Infections such as bacterial vaginosis, candidiasis, and actinomycosis were detected in 13 (18.6%) patients. Pap smear tests should be performed in female psoriasis patients to detect premalignant lesions of the cervix before the initiation of biological agent treatment. Moreover, psoriasis treatment guidelines should be updated accordingly\"","PeriodicalId":21298,"journal":{"name":"Romanian Journal of Military Medicine","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47245265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-01DOI: 10.55453/rjmm.2023.126.4.17
I. A. Vacaroiu, L. F. Feier, M. Georgescu, C. David, E. Cuiban, Andra-Elena Balcangiu-Stroescu, Sebastian Isac, L. Răducu, A. Călinoiu, D. Radulescu
Background and Objectives: Chronic Kidney Disease (CKD) affects 6,7% of the adult population in Romania and is associated with high morbidity. About one out of three adults with diabetes has kidney disease. According to current literature data, the prevalence of diabetes is very high, up to 11,6%, of whom 2,4% had undiagnosed diabetes, and is the leading cause of kidney damage and the need for renal replacement therapy (RRT). COVID-19 has brought with it a lot of unanswered questions, regarding the risk factors, the disease evolution, and the treatment possibilities. It became clear that diabetic kidney disease (DKD) is among the independent risk factors that predict unfavorable outcomes upon SARS-CoV-2 infection, so we aimed to evaluate the characteristics of diabetic and non-diabetic dialyzed patients, COVID-19 positive. Materials and Methods: It is an observational, single-center study that analyzed type 2 diabetes mellitus and non–diabetic patients in maintenance hemodialysis hospitalized for SARS CoV-2 infection. Results: A total of 101 adult dialyzed patients were admitted with a SARS-CoV-2 RT-PCR positive test, out of which 42 had a long history of diabetes mellitus type 2 and 59 of them have been known with other etiologies of CKD. Hypertension and heart disease were the most commonly associated comorbidities. Inflammatory markers and anemia were significantly increased in diabetic patients compared to non-diabetic. Conclusions: We found that anemia was more severe in patients COVID-19-positive MHD T2DM patients.
{"title":"Haemodialysis Patients with Type 2 Diabetes Mellitus and COVID-19: An Observational Study","authors":"I. A. Vacaroiu, L. F. Feier, M. Georgescu, C. David, E. Cuiban, Andra-Elena Balcangiu-Stroescu, Sebastian Isac, L. Răducu, A. Călinoiu, D. Radulescu","doi":"10.55453/rjmm.2023.126.4.17","DOIUrl":"https://doi.org/10.55453/rjmm.2023.126.4.17","url":null,"abstract":"Background and Objectives: Chronic Kidney Disease (CKD) affects 6,7% of the adult population in Romania and is associated with high morbidity. About one out of three adults with diabetes has kidney disease. According to current literature data, the prevalence of diabetes is very high, up to 11,6%, of whom 2,4% had undiagnosed diabetes, and is the leading cause of kidney damage and the need for renal replacement therapy (RRT). COVID-19 has brought with it a lot of unanswered questions, regarding the risk factors, the disease evolution, and the treatment possibilities. It became clear that diabetic kidney disease (DKD) is among the independent risk factors that predict unfavorable outcomes upon SARS-CoV-2 infection, so we aimed to evaluate the characteristics of diabetic and non-diabetic dialyzed patients, COVID-19 positive. Materials and Methods: It is an observational, single-center study that analyzed type 2 diabetes mellitus and non–diabetic patients in maintenance hemodialysis hospitalized for SARS CoV-2 infection. Results: A total of 101 adult dialyzed patients were admitted with a SARS-CoV-2 RT-PCR positive test, out of which 42 had a long history of diabetes mellitus type 2 and 59 of them have been known with other etiologies of CKD. Hypertension and heart disease were the most commonly associated comorbidities. Inflammatory markers and anemia were significantly increased in diabetic patients compared to non-diabetic. Conclusions: We found that anemia was more severe in patients COVID-19-positive MHD T2DM patients.","PeriodicalId":21298,"journal":{"name":"Romanian Journal of Military Medicine","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47522291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-01DOI: 10.55453/rjmm.2023.126.4.13
D. Anghel, Iulia N. Nicolau, Liana I. Mihalca, O. Petrache, R. Costache, D. Opriș-Belinski, V. Bojinca, F. Ioniță Radu
Pulmonary hypertension (PH) has gained more and more attention in the last years given the increased mortality and morbidity rate and in particular pulmonary arterial hypertension associated with autoimmune diseases (a specific subgroup of PH), entities with an increasing incidence and prevalence globally. Among these, systemic sclerosis is of particular interest, being the most common among connective tissue diseases (CTDs) with PH as a major complication. Other CTDs such as mixed connective tissue disease (MCTD), systemic lupus erythematosus (SLE), primary Sjogren's syndrome, and dermatomyositis may also develop PH as a complication of these severe and complex conditions, which can have a major impact on prognosis and quality of life. PH has also been reported in rheumatoid arthritis and ankylosing spondylitis but further studies are necessary. Several studies have shown that the 3-year survival rate for patients with systemic sclerosis-associated with pulmonary hypertension (SSc-PH) is between 31% and 52%, while the 5-year survival rate is below <50%. Therefore, an early and accurate diagnosis as well as subsequent management of PH in these conditions is mandatory, since survival remains suboptimal despite treatment advances. The aim of this article is to provide an overview of different autoimmune diseases associated with PH and to provide an easy reference source on current best practices.
{"title":"Pulmonary Hypertension in Autoimmune Diseases – A Review of New Concepts in Screening, Diagnosis and Therapeutic Management","authors":"D. Anghel, Iulia N. Nicolau, Liana I. Mihalca, O. Petrache, R. Costache, D. Opriș-Belinski, V. Bojinca, F. Ioniță Radu","doi":"10.55453/rjmm.2023.126.4.13","DOIUrl":"https://doi.org/10.55453/rjmm.2023.126.4.13","url":null,"abstract":"Pulmonary hypertension (PH) has gained more and more attention in the last years given the increased mortality and morbidity rate and in particular pulmonary arterial hypertension associated with autoimmune diseases (a specific subgroup of PH), entities with an increasing incidence and prevalence globally. Among these, systemic sclerosis is of particular interest, being the most common among connective tissue diseases (CTDs) with PH as a major complication. Other CTDs such as mixed connective tissue disease (MCTD), systemic lupus erythematosus (SLE), primary Sjogren's syndrome, and dermatomyositis may also develop PH as a complication of these severe and complex conditions, which can have a major impact on prognosis and quality of life. PH has also been reported in rheumatoid arthritis and ankylosing spondylitis but further studies are necessary. Several studies have shown that the 3-year survival rate for patients with systemic sclerosis-associated with pulmonary hypertension (SSc-PH) is between 31% and 52%, while the 5-year survival rate is below <50%. Therefore, an early and accurate diagnosis as well as subsequent management of PH in these conditions is mandatory, since survival remains suboptimal despite treatment advances. The aim of this article is to provide an overview of different autoimmune diseases associated with PH and to provide an easy reference source on current best practices.","PeriodicalId":21298,"journal":{"name":"Romanian Journal of Military Medicine","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45279899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-01DOI: 10.55453/rjmm.2023.126.4.18
G. Avram, A. Stefan, Radu Paraschiv, Monica Dugăeșescu, Leonardo Tillieci-Minnetti
Background: As total hip replacement cases increase year after year, registry-wide data becomes increasingly important in order to assess pathology distribution, reimbursement efficiency as well as physician performance. In order to assess all these factors patient evolution needs to be documented after surgery as well, but the main impediment to doing this is losing patients to follow-up. For this reason, the present study aims to perform a descriptive analysis of the hospital’s internal registry data as well as to determine what percentage of patients can be expected to return to follow-up after total hip replacement. Methods: A query of the hospital’s internal registry data in the last years was performed. Patient demographics, county distribution as well as ICD-10 code usage were documented. Data standardization was performed to determine the probability and cumulative distribution of the patient’s age. The chi2 test of independence was used to assess whether there is a correlation between the patient’s gender and ICD-10 codes. Pot hoc power analysis was performed to assess the accuracy of correlation analysis. Results: Only 29.6% of the patients undergoing total hip replacement are from the county within which the hospital is located. 25% of the patients were under 60 years old. Conclusions: Current registry data reveals that most patients undergoing total hip replacement are around 67.5 ± 11 years old, suffer from unilateral or bilateral primary or secondary hip osteoarthritis and only 29.6% of them are likely to return to follow-up.
{"title":"Descriptive Analysis of Internal Registry Data on Cemented and Uncemented Total Hip Arthroplasty","authors":"G. Avram, A. Stefan, Radu Paraschiv, Monica Dugăeșescu, Leonardo Tillieci-Minnetti","doi":"10.55453/rjmm.2023.126.4.18","DOIUrl":"https://doi.org/10.55453/rjmm.2023.126.4.18","url":null,"abstract":"Background: As total hip replacement cases increase year after year, registry-wide data becomes increasingly important in order to assess pathology distribution, reimbursement efficiency as well as physician performance. In order to assess all these factors patient evolution needs to be documented after surgery as well, but the main impediment to doing this is losing patients to follow-up. For this reason, the present study aims to perform a descriptive analysis of the hospital’s internal registry data as well as to determine what percentage of patients can be expected to return to follow-up after total hip replacement. Methods: A query of the hospital’s internal registry data in the last years was performed. Patient demographics, county distribution as well as ICD-10 code usage were documented. Data standardization was performed to determine the probability and cumulative distribution of the patient’s age. The chi2 test of independence was used to assess whether there is a correlation between the patient’s gender and ICD-10 codes. Pot hoc power analysis was performed to assess the accuracy of correlation analysis. Results: Only 29.6% of the patients undergoing total hip replacement are from the county within which the hospital is located. 25% of the patients were under 60 years old. Conclusions: Current registry data reveals that most patients undergoing total hip replacement are around 67.5 ± 11 years old, suffer from unilateral or bilateral primary or secondary hip osteoarthritis and only 29.6% of them are likely to return to follow-up.","PeriodicalId":21298,"journal":{"name":"Romanian Journal of Military Medicine","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47128984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.55453/rjmm.2023.126.2.10
E. Ashrafi, F. Bazvandi, F. Izadkhah, T. Dehdari, Bahare Izadi, Omid Safari, M. Mansourian
"Introduction: Self-care behaviors are very important to control type 2 diabetes. The current study was conducted aiming at determining the effect of the educational intervention based on mobile short message service on the self-care behaviors in patients with type 2 diabetes in Khorram Abad. Methods: This study was a semi-experimental study on 191 patients with type 2 diabetes (45case and 45 controls). Data collection tools included a demographic information form, International Physical Activity Questionnaire, Self-Care Scale, and Self-Efficacy Scale. Three to four educational messages were sent daily through mobile phones as an educational intervention. Data were analyzed with SPSS V24 at a significance level of 0.05. Findings: The data analysis indicated that the average score of self-care, self-efficacy, and blood sugar was significantly higher in the case group than in the control group before and after the intervention (P<0.001). However, in terms of the physical activity variable, this relationship was not statistically significant in the case and control groups. Conclusion: Educational interventions to empower diabetic patients by strengthening their self-care can be an effective way to improve the health of diabetic patients. Therefore, it is suggested to use patient empowerment programs, especially with a self-care approach, to improve the health of patients. "
{"title":"\"Survey the Effect of Educational Intervention Based on Mobile Short Message Service (SMS) on Self-Care in Patients with Type 2 Diabetes Referring to the Diabetes Clinic in Khorram Abad City \"","authors":"E. Ashrafi, F. Bazvandi, F. Izadkhah, T. Dehdari, Bahare Izadi, Omid Safari, M. Mansourian","doi":"10.55453/rjmm.2023.126.2.10","DOIUrl":"https://doi.org/10.55453/rjmm.2023.126.2.10","url":null,"abstract":"\"Introduction: Self-care behaviors are very important to control type 2 diabetes. The current study was conducted aiming at determining the effect of the educational intervention based on mobile short message service on the self-care behaviors in patients with type 2 diabetes in Khorram Abad. Methods: This study was a semi-experimental study on 191 patients with type 2 diabetes (45case and 45 controls). Data collection tools included a demographic information form, International Physical Activity Questionnaire, Self-Care Scale, and Self-Efficacy Scale. Three to four educational messages were sent daily through mobile phones as an educational intervention. Data were analyzed with SPSS V24 at a significance level of 0.05. Findings: The data analysis indicated that the average score of self-care, self-efficacy, and blood sugar was significantly higher in the case group than in the control group before and after the intervention (P<0.001). However, in terms of the physical activity variable, this relationship was not statistically significant in the case and control groups. Conclusion: Educational interventions to empower diabetic patients by strengthening their self-care can be an effective way to improve the health of diabetic patients. Therefore, it is suggested to use patient empowerment programs, especially with a self-care approach, to improve the health of patients. \"","PeriodicalId":21298,"journal":{"name":"Romanian Journal of Military Medicine","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42066941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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