Pub Date : 2022-01-01DOI: 10.21577/1984-6835.20220066
R. Soares, Beatriz César Maestá, Felipe Debize da Motta, R. Naegele, Carlos Eduardo Soares Canejo Pinheiro da Cunha
In Brazil adopted different Non-Pharmacological Intervention measures (NPIs) to reduce the levels of transmission and contagion of the novel Coronavirus SARS-CoV-2, the pathogen causing the COVID-19 pandemic. The objective of this work was to evaluate the impact of Non-Pharmacological Intervention measures on the composition and treatment efficacy of Landfill Leachate treated by Reverse Osmosis in the city of Campos dos Goytacazes, Rio de Janeiro. It was observed that the Lockdown and the massive use of personal hygiene/cleaning materials, as well as the increase in food consumption, provided an unprecedented 140% overload in the daily generation of Municipal Solid Waste (MSW) in the Campos dos Goytacazes Landfill. The Leachate from this Landfill presented a slightly alkaline pH (pH ≈ 8.0), high concentrations of dissolved organic matter (BOD 5 and COD), and ammoniacal nitrogen. In addition, it was observed that 23% of the parameters in the raw leachate exceeded the respective maximum allowable values recommended by the federal legislation. However, in the period evaluated by this study, the Reverse Osmosis was technically and environmentally effective in treating the raw leachate, not being observed any result in the treated leachate that exceeded the Resolution CONAMA 430/2011.
{"title":"Impact Assessment of 2020 COVID-19 Lockdown on Landfill Leachate Treatment in Rio de Janeiro","authors":"R. Soares, Beatriz César Maestá, Felipe Debize da Motta, R. Naegele, Carlos Eduardo Soares Canejo Pinheiro da Cunha","doi":"10.21577/1984-6835.20220066","DOIUrl":"https://doi.org/10.21577/1984-6835.20220066","url":null,"abstract":"In Brazil adopted different Non-Pharmacological Intervention measures (NPIs) to reduce the levels of transmission and contagion of the novel Coronavirus SARS-CoV-2, the pathogen causing the COVID-19 pandemic. The objective of this work was to evaluate the impact of Non-Pharmacological Intervention measures on the composition and treatment efficacy of Landfill Leachate treated by Reverse Osmosis in the city of Campos dos Goytacazes, Rio de Janeiro. It was observed that the Lockdown and the massive use of personal hygiene/cleaning materials, as well as the increase in food consumption, provided an unprecedented 140% overload in the daily generation of Municipal Solid Waste (MSW) in the Campos dos Goytacazes Landfill. The Leachate from this Landfill presented a slightly alkaline pH (pH ≈ 8.0), high concentrations of dissolved organic matter (BOD 5 and COD), and ammoniacal nitrogen. In addition, it was observed that 23% of the parameters in the raw leachate exceeded the respective maximum allowable values recommended by the federal legislation. However, in the period evaluated by this study, the Reverse Osmosis was technically and environmentally effective in treating the raw leachate, not being observed any result in the treated leachate that exceeded the Resolution CONAMA 430/2011.","PeriodicalId":21315,"journal":{"name":"Revista Virtual de Química","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89511639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21577/1984-6835.20220069
Ana Paula Azevêdo Macêdo, Mariane dos Santos Gonçalves, Oscar Caetano da Silva Neto, Ricardo David Couto, Jorge Mauricio David
tea From a of view, phytochemical analyzes is essential to know the composition and concentration of compounds in green tea, as well as the stability of these components. In this study the phytochemical properties and chemical stability of green tea were evaluated. A sample, widely sold in was submitted to following of analyzes for detection of the main compounds and evaluation of the stability of green tea extract preparations by HPLC. As result, the green tea extract presented caffeine (34.4%), epi catechin gallate (11.9%), and epi gallocatechin (5.8%) as main identified compounds in its composition. During the four weeks of evaluation, the main metabolites presented small decomposition rate (2.4 to 2.9%). In addition, the phytochemical analysis revealed the presence of several secondary metabolites in their composition (alkaloids, glycosides, saponins, tannins, terpenoids, caffeine and flavonoids). This demonstrates that green tea extract has compounds with properties that bring health benefits but also as it contains other secondary metabolites, and its therapeutic use should be carefully evaluated.
{"title":"Phytochemical Characterization and Chemical Stability of Green Tea Extract","authors":"Ana Paula Azevêdo Macêdo, Mariane dos Santos Gonçalves, Oscar Caetano da Silva Neto, Ricardo David Couto, Jorge Mauricio David","doi":"10.21577/1984-6835.20220069","DOIUrl":"https://doi.org/10.21577/1984-6835.20220069","url":null,"abstract":"tea From a of view, phytochemical analyzes is essential to know the composition and concentration of compounds in green tea, as well as the stability of these components. In this study the phytochemical properties and chemical stability of green tea were evaluated. A sample, widely sold in was submitted to following of analyzes for detection of the main compounds and evaluation of the stability of green tea extract preparations by HPLC. As result, the green tea extract presented caffeine (34.4%), epi catechin gallate (11.9%), and epi gallocatechin (5.8%) as main identified compounds in its composition. During the four weeks of evaluation, the main metabolites presented small decomposition rate (2.4 to 2.9%). In addition, the phytochemical analysis revealed the presence of several secondary metabolites in their composition (alkaloids, glycosides, saponins, tannins, terpenoids, caffeine and flavonoids). This demonstrates that green tea extract has compounds with properties that bring health benefits but also as it contains other secondary metabolites, and its therapeutic use should be carefully evaluated.","PeriodicalId":21315,"journal":{"name":"Revista Virtual de Química","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90264474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21577/1984-6835.20220021
R. Andrighetto, Vanessa Griebeler Sebastiani
This article is a mirror of the initial clippings of a project junior scientific initiation project and aims to make available a scientific text, in Portuguese language, built in the light of the main highlights that brought the chloroquine and hydroxychloroquine into the spotlight of the current pandemic context. In view of this context, the objective of this article, of an eminently theoretical nature, is to contribute to the delimitation of fundamental concepts in the field of organic chemistry. The methodology adopted for this descriptive and exploratory research, with a qualitative approach, consisted of systematically reviewing the literature, using indexed databases, to contextualize factual points about the historical origin (natural and synthetic) and the pharmacological properties of heterocycles correlated to the theme of COVID-19 pandemic. We approach concepts and structural chemical formulas that support the area of organic chemistry and, more specifically, heterocyclic chemistry. And, through this compilation, we present a way of quick access to the recent information anchored in journals of national and international impact.
{"title":"The Heterocycles in the Context of COVID-19 (Part 1): a Review with Highlights of the Pandemic","authors":"R. Andrighetto, Vanessa Griebeler Sebastiani","doi":"10.21577/1984-6835.20220021","DOIUrl":"https://doi.org/10.21577/1984-6835.20220021","url":null,"abstract":"This article is a mirror of the initial clippings of a project junior scientific initiation project and aims to make available a scientific text, in Portuguese language, built in the light of the main highlights that brought the chloroquine and hydroxychloroquine into the spotlight of the current pandemic context. In view of this context, the objective of this article, of an eminently theoretical nature, is to contribute to the delimitation of fundamental concepts in the field of organic chemistry. The methodology adopted for this descriptive and exploratory research, with a qualitative approach, consisted of systematically reviewing the literature, using indexed databases, to contextualize factual points about the historical origin (natural and synthetic) and the pharmacological properties of heterocycles correlated to the theme of COVID-19 pandemic. We approach concepts and structural chemical formulas that support the area of organic chemistry and, more specifically, heterocyclic chemistry. And, through this compilation, we present a way of quick access to the recent information anchored in journals of national and international impact.","PeriodicalId":21315,"journal":{"name":"Revista Virtual de Química","volume":"119 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78554309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21577/1984-6835.20220080
Thaiany S. C. Bressiani, Lucas Lorenzini, Tainara R. Neves, Matheus B. Alvarenga, Sandra A. D. Ferreira, Paulo R. G. Moura, Maria de Fátima F. Lelis
The present work addresses the environmental issue of solid waste in an experimental chemistry class aiming to reduce mining and plastic waste to produce plastic wood. The activities were developed with the participation of undergraduate students from the Chemistry course (UFES – Universidade Federal do Espírito Santo) in the discipline “ Waste Treatment in the Environment” and students from the Civil Engineering course, that are using “ Environmental Education ” as theoretical support. The tailings used were characterized by XRD indicating the presence of SiO 2 (silica), Fe 2 O 3 (hematite) and Al 2 Si 2 O 5 (OH) 4 (kaolinite) as main components. The plastic wood sample produced showed surface aspects and color like those of natural wood. The preparation of a technological, sustainable, and economically viable product from waste was discussed in the classroom. Those experimental activities allowed a joint reflection with the students about the environmental issues and how the use of waste, to prepare new materials in the classroom, may promote transformative training, capable of influencing the future of these professionals and hopefully leading to more creative decision-making, with a focus on sustainable development and social responsibilities.
本研究在实验化学课堂上解决了固体废物的环境问题，旨在减少采矿和塑料废物生产塑料木材。这些活动是在“环境中的废物处理”学科的化学专业本科生(ues - universsidade Federal do Espírito Santo)和土木工程专业学生的参与下开展的，他们将“环境教育”作为理论支持。采用XRD对尾矿进行了表征，表明主要成分为sio2(二氧化硅)、fe2o3(赤铁矿)和al2si2o5 (OH) 4(高岭石)。制作的塑木样品表面和颜色与天然木材相似。在课堂上讨论了从废物中制备技术，可持续和经济上可行的产品。这些实验活动使学生能够共同思考环境问题，以及如何利用废物在课堂上准备新材料，促进变革性培训，能够影响这些专业人员的未来，并有希望导致更具创造性的决策，重点是可持续发展和社会责任。
{"title":"Plastic Wood Production from Mining Tailings and Plastic Waste: An Experimental Study","authors":"Thaiany S. C. Bressiani, Lucas Lorenzini, Tainara R. Neves, Matheus B. Alvarenga, Sandra A. D. Ferreira, Paulo R. G. Moura, Maria de Fátima F. Lelis","doi":"10.21577/1984-6835.20220080","DOIUrl":"https://doi.org/10.21577/1984-6835.20220080","url":null,"abstract":"The present work addresses the environmental issue of solid waste in an experimental chemistry class aiming to reduce mining and plastic waste to produce plastic wood. The activities were developed with the participation of undergraduate students from the Chemistry course (UFES – Universidade Federal do Espírito Santo) in the discipline “ Waste Treatment in the Environment” and students from the Civil Engineering course, that are using “ Environmental Education ” as theoretical support. The tailings used were characterized by XRD indicating the presence of SiO 2 (silica), Fe 2 O 3 (hematite) and Al 2 Si 2 O 5 (OH) 4 (kaolinite) as main components. The plastic wood sample produced showed surface aspects and color like those of natural wood. The preparation of a technological, sustainable, and economically viable product from waste was discussed in the classroom. Those experimental activities allowed a joint reflection with the students about the environmental issues and how the use of waste, to prepare new materials in the classroom, may promote transformative training, capable of influencing the future of these professionals and hopefully leading to more creative decision-making, with a focus on sustainable development and social responsibilities.","PeriodicalId":21315,"journal":{"name":"Revista Virtual de Química","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75400341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21577/1984-6835.20220140
Bruno D. Q. Villard, Nivaldo G.P. Filho, Paulo V.R. Gomes, J. Nandenha, Camila M. Godoi, Thais Lie Tagomori, N. Azeredo, Rodrigo F.B. de Souza, Almir O. Neto, Priscilla J. Zambiazi
The processing of biomass to obtain fuels such as ethanol results in generating waste and polluting the environment. However, to meet energy demand and simultaneously reduce environmental pollution, fuel cells are promising devices for converting chemical compounds into electricity. Fuel cells can be powered by various types of liquids, including the sugars available in sugarcane extract, with high energy potential. Fuel cells employ the use of noble metals as electrocatalysts, such as Pt or Pd, to carry out the oxidation of these fuels. In this sense, this work reports the study of the oxidation of sugarcane extract in these different noble metals. The platinum catalyst was shown to be more active for the oxidation of sugars, resulting in a power density 10 times greater than Pd/C using a 50% diluted sugarcane extract solution, resulting in promising fuel cell systems. To produce ecologically correct electrical energy for the industry in general.
{"title":"Electrocatalytic Performance of Pd/C and Pt/C for Power Generation from Sugarcane Extract in Direct Liquid Fuel Cell","authors":"Bruno D. Q. Villard, Nivaldo G.P. Filho, Paulo V.R. Gomes, J. Nandenha, Camila M. Godoi, Thais Lie Tagomori, N. Azeredo, Rodrigo F.B. de Souza, Almir O. Neto, Priscilla J. Zambiazi","doi":"10.21577/1984-6835.20220140","DOIUrl":"https://doi.org/10.21577/1984-6835.20220140","url":null,"abstract":"The processing of biomass to obtain fuels such as ethanol results in generating waste and polluting the environment. However, to meet energy demand and simultaneously reduce environmental pollution, fuel cells are promising devices for converting chemical compounds into electricity. Fuel cells can be powered by various types of liquids, including the sugars available in sugarcane extract, with high energy potential. Fuel cells employ the use of noble metals as electrocatalysts, such as Pt or Pd, to carry out the oxidation of these fuels. In this sense, this work reports the study of the oxidation of sugarcane extract in these different noble metals. The platinum catalyst was shown to be more active for the oxidation of sugars, resulting in a power density 10 times greater than Pd/C using a 50% diluted sugarcane extract solution, resulting in promising fuel cell systems. To produce ecologically correct electrical energy for the industry in general.","PeriodicalId":21315,"journal":{"name":"Revista Virtual de Química","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75909092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21577/1984-6835.20220107
Juliana G. de Morais, Clara S. C. Siqueira, Yasmine B. Queiroz, Vanessa C. S. Amaral, Luciana M. Ramos
Benzodiazepines (BZD) are heterocyclic compounds which stand out for their sedative, hypnotic, anxiolytic, and anticonvulsant activity. In order to develop more attractive syntheses based on literature data, this systematic review has analyzed the scientific articles on the synthesis and biological evaluation of benzodiazepine derivatives, application of catalysts, green solvents and strategic substitutions into this nucleus. A bibliographic research was performed in the Web of Science and PubMed databases and resulted in 522 articles. Among these, 80 of these articles met the inclusion criteria and were selected to compose this review. The structures that show better biological activity and the synthesis strategies to obtain these derivatives were reported. New perspectives in the synthesis of benzodiazepines were possible with this review.
苯二氮卓类(BZD)是一种杂环化合物，具有镇静、催眠、抗焦虑和抗惊厥作用。为了在文献资料的基础上开发出更有吸引力的合成方法，本系统综述分析了苯二氮卓类衍生物的合成和生物学评价、催化剂的应用、绿色溶剂和策略取代等方面的科学文章。在Web of Science和PubMed数据库中进行了书目研究，结果得出522篇文章。其中80篇符合纳入标准，入选本综述。报道了具有较好生物活性的结构及其合成策略。本综述为苯二氮卓类化合物的合成开辟了新的前景。
{"title":"Synthetic and Biological Importance of Benzodiazepines: A Systematic Review","authors":"Juliana G. de Morais, Clara S. C. Siqueira, Yasmine B. Queiroz, Vanessa C. S. Amaral, Luciana M. Ramos","doi":"10.21577/1984-6835.20220107","DOIUrl":"https://doi.org/10.21577/1984-6835.20220107","url":null,"abstract":"Benzodiazepines (BZD) are heterocyclic compounds which stand out for their sedative, hypnotic, anxiolytic, and anticonvulsant activity. In order to develop more attractive syntheses based on literature data, this systematic review has analyzed the scientific articles on the synthesis and biological evaluation of benzodiazepine derivatives, application of catalysts, green solvents and strategic substitutions into this nucleus. A bibliographic research was performed in the Web of Science and PubMed databases and resulted in 522 articles. Among these, 80 of these articles met the inclusion criteria and were selected to compose this review. The structures that show better biological activity and the synthesis strategies to obtain these derivatives were reported. New perspectives in the synthesis of benzodiazepines were possible with this review.","PeriodicalId":21315,"journal":{"name":"Revista Virtual de Química","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72957430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21577/1984-6835.20230013
Jaqueline Vieira Piovezana-Gomes, P. Anunciação, Júlia d’Almeida Francisquini, Livya Alves Oliveira, L. F. Cappa de Oliveira, Antônio Fernandes de Carvalho, R. Stephani, Ítalo Tuler Perrone, Ceres Mattos Della Lucia
{"title":"Whey Protein Concentrate admixture of Turmeric Extract: The Effect Of Drying Method","authors":"Jaqueline Vieira Piovezana-Gomes, P. Anunciação, Júlia d’Almeida Francisquini, Livya Alves Oliveira, L. F. Cappa de Oliveira, Antônio Fernandes de Carvalho, R. Stephani, Ítalo Tuler Perrone, Ceres Mattos Della Lucia","doi":"10.21577/1984-6835.20230013","DOIUrl":"https://doi.org/10.21577/1984-6835.20230013","url":null,"abstract":"","PeriodicalId":21315,"journal":{"name":"Revista Virtual de Química","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73010529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21577/1984-6835.20220115
M. Gonçalves da Rocha, S. Nakagaki, Guilherme Sippel Machado Sippel Machado
Catalysis is one of the areas of science whose history is little explored in textbooks used in the teaching of chemistry, which rarely dedicate part of the text to tell how this knowledge was built. Nowadays, catalysis is one of the most important aspects of industrial, laboratory and sustainable chemistry. This paper is meant to make a historical review of how some great names in the history of chemistry built all this knowledge, with special attention to the work of Elizabeth Fulhame, a British scientist, who pioneered the research in catalytic chemical reactions. In addition, other names and contributions of several scientists to the history and development of catalysis will be discussed, as well as the Brazilian contribution to the production of knowledge in this field. This work aims to contribute to broaden the vision of one of the most important branches of modern chemistry in several fronts, including financial, environmental and social.
{"title":"Revisiting the History of Catalysis: Elizabeth Fulhame’s Contributions and Other Historical Aspects.","authors":"M. Gonçalves da Rocha, S. Nakagaki, Guilherme Sippel Machado Sippel Machado","doi":"10.21577/1984-6835.20220115","DOIUrl":"https://doi.org/10.21577/1984-6835.20220115","url":null,"abstract":"Catalysis is one of the areas of science whose history is little explored in textbooks used in the teaching of chemistry, which rarely dedicate part of the text to tell how this knowledge was built. Nowadays, catalysis is one of the most important aspects of industrial, laboratory and sustainable chemistry. This paper is meant to make a historical review of how some great names in the history of chemistry built all this knowledge, with special attention to the work of Elizabeth Fulhame, a British scientist, who pioneered the research in catalytic chemical reactions. In addition, other names and contributions of several scientists to the history and development of catalysis will be discussed, as well as the Brazilian contribution to the production of knowledge in this field. This work aims to contribute to broaden the vision of one of the most important branches of modern chemistry in several fronts, including financial, environmental and social.","PeriodicalId":21315,"journal":{"name":"Revista Virtual de Química","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74498157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21577/1984-6835.20220113
Keoma K. L. Cavalcante, Gabrielle C. Calegari, A. Orsato, Carla C. Perez
The oxidative stress is a biological condition resulting from an imbalance in the Reactive Oxygen Species production, which occurs mainly through the NADPH oxidase (NOX), a transmembrane enzyme that acts in a pro-inflammatory mechanism. Due to the toxicity of these species to living tissue, this condition has been studied over the years as a leading cause of human disease, affecting from heart and lung tissues to the Central Nervous System. This work brings important information about the several diseases related to the Oxidative Stress condition, their origins and main causes, as well as raising data from the last years about the antioxidant compounds, anti-inflammatory and NOX inhibitors used in their prevention over the last years. Compounds such as carboxylic acids and phenolics esthers amides and peptides are reported in this work to have important structural characteristics in the activity against oxidative burst and its various modulations.
{"title":"Oxidative Stress and Nox: Related Diseases and Main Classes of Synthetic and Natural Inhibitors","authors":"Keoma K. L. Cavalcante, Gabrielle C. Calegari, A. Orsato, Carla C. Perez","doi":"10.21577/1984-6835.20220113","DOIUrl":"https://doi.org/10.21577/1984-6835.20220113","url":null,"abstract":"The oxidative stress is a biological condition resulting from an imbalance in the Reactive Oxygen Species production, which occurs mainly through the NADPH oxidase (NOX), a transmembrane enzyme that acts in a pro-inflammatory mechanism. Due to the toxicity of these species to living tissue, this condition has been studied over the years as a leading cause of human disease, affecting from heart and lung tissues to the Central Nervous System. This work brings important information about the several diseases related to the Oxidative Stress condition, their origins and main causes, as well as raising data from the last years about the antioxidant compounds, anti-inflammatory and NOX inhibitors used in their prevention over the last years. Compounds such as carboxylic acids and phenolics esthers amides and peptides are reported in this work to have important structural characteristics in the activity against oxidative burst and its various modulations.","PeriodicalId":21315,"journal":{"name":"Revista Virtual de Química","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73350063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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