Pub Date : 2023-07-08DOI: 10.1016/j.rpsm.2023.04.002
Krzysztof Kowalski, Błażej Misiak
The outbreak of the Coronavirus Disease 2019 (COVID-19) pandemic in 2020 caused a rapid worsening of global mental health. Patients with severe mental disorders, including schizophrenia, are at higher risk of being infected. The neuroinvasive potential of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has been confirmed. The aim of this article was to present a narrative and comprehensive review of multidimensional associations between schizophrenia and COVID-19 with special emphasis on common biological pathways. Online searches were performed in the PubMed database and covered the publication period until September 17, 2022. Search terms included "psychosis", "schizophrenia", "inflammation" and "COVID-19". Viewed as a neuroinflammatory state, schizophrenia shares several neurobiological mechanisms with the COVID-19. Environmental stress, common comorbidities of schizophrenia and adverse effects of antipsychotic treatment are associated with the higher severity and mortality of the COVID-19. Additionally, more frequent relapses of psychosis have been observed, and might be related to lower treatment adherence. In the context of clinical manifestation, higher level of negative symptoms has been identified among patients with schizophrenia during the pandemic. Improvements in mental health care policy and treatment adjustment are necessary to protect people with schizophrenia who are the population that is particularly vulnerable to the consequences of the COVID-19 pandemic. Future research will show if prenatal infection with the SARS-CoV-2 increases a risk of psychosis.
{"title":"Schizophrenia and the COVID-19 pandemic: A narrative review from the biomedical perspective.","authors":"Krzysztof Kowalski, Błażej Misiak","doi":"10.1016/j.rpsm.2023.04.002","DOIUrl":"https://doi.org/10.1016/j.rpsm.2023.04.002","url":null,"abstract":"<p><p>The outbreak of the Coronavirus Disease 2019 (COVID-19) pandemic in 2020 caused a rapid worsening of global mental health. Patients with severe mental disorders, including schizophrenia, are at higher risk of being infected. The neuroinvasive potential of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has been confirmed. The aim of this article was to present a narrative and comprehensive review of multidimensional associations between schizophrenia and COVID-19 with special emphasis on common biological pathways. Online searches were performed in the PubMed database and covered the publication period until September 17, 2022. Search terms included \"psychosis\", \"schizophrenia\", \"inflammation\" and \"COVID-19\". Viewed as a neuroinflammatory state, schizophrenia shares several neurobiological mechanisms with the COVID-19. Environmental stress, common comorbidities of schizophrenia and adverse effects of antipsychotic treatment are associated with the higher severity and mortality of the COVID-19. Additionally, more frequent relapses of psychosis have been observed, and might be related to lower treatment adherence. In the context of clinical manifestation, higher level of negative symptoms has been identified among patients with schizophrenia during the pandemic. Improvements in mental health care policy and treatment adjustment are necessary to protect people with schizophrenia who are the population that is particularly vulnerable to the consequences of the COVID-19 pandemic. Future research will show if prenatal infection with the SARS-CoV-2 increases a risk of psychosis.</p>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9946312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-03DOI: 10.1016/j.rpsm.2023.05.002
Marta Perez-Rando, Carlota Penades-Gomiz, Pablo Martinez-Marin, Gracián García-Martí, Eduardo J Aguilar, Maria J Escarti, Eva Grasa, Iluminada Corripio, Julio Sanjuan, Juan Nacher
Introduction: Auditory hallucinations (AH) are one of the most prevalent symptoms of schizophrenia. They might cause several brain alterations, especially changes in the volumes of hippocampus and amygdala, regions related to the relay and processing of auditory cues and emotional memories.
Material and methods: We have recruited 41 patients with schizophrenia and persistent AH, 35 patients without AH, and 55 healthy controls. Using their MRIs, we have performed semiautomatic segmentations of the hippocampus and amygdala using Freesurfer. We have also performed bilateral correlations between the total PSYRATS score and the volumes of affected subregions and nuclei.
Results: In the hippocampus, we found bilateral increases in the volume of its hippocampal fissure and decreases in the right fimbria in patients with and without AH. The volume of the right hippocampal tail and left head of the granule cell layer from the dentate gyrus were decreased in patients with AH. In the amygdala, we found its left total volume was shrunk, and there was a decrease of its left accessory basal nucleus in patients with AH.
Conclusions: We have detected volume alterations of different limbic structures likely due to the presence of AH. The volumes of the right hippocampal tail and left head of the granule cell layer from the dentate gyrus, and total volume of the amygdala and its accessory basal nucleus, were only affected in patients with AH. Bilateral volume alterations in the hippocampal fissure and right fimbria seem inherent of schizophrenia and due to traits not contemplated in our research.
{"title":"Volume alterations of the hippocampus and amygdala in patients with schizophrenia and persistent auditory hallucinations.","authors":"Marta Perez-Rando, Carlota Penades-Gomiz, Pablo Martinez-Marin, Gracián García-Martí, Eduardo J Aguilar, Maria J Escarti, Eva Grasa, Iluminada Corripio, Julio Sanjuan, Juan Nacher","doi":"10.1016/j.rpsm.2023.05.002","DOIUrl":"https://doi.org/10.1016/j.rpsm.2023.05.002","url":null,"abstract":"<p><strong>Introduction: </strong>Auditory hallucinations (AH) are one of the most prevalent symptoms of schizophrenia. They might cause several brain alterations, especially changes in the volumes of hippocampus and amygdala, regions related to the relay and processing of auditory cues and emotional memories.</p><p><strong>Material and methods: </strong>We have recruited 41 patients with schizophrenia and persistent AH, 35 patients without AH, and 55 healthy controls. Using their MRIs, we have performed semiautomatic segmentations of the hippocampus and amygdala using Freesurfer. We have also performed bilateral correlations between the total PSYRATS score and the volumes of affected subregions and nuclei.</p><p><strong>Results: </strong>In the hippocampus, we found bilateral increases in the volume of its hippocampal fissure and decreases in the right fimbria in patients with and without AH. The volume of the right hippocampal tail and left head of the granule cell layer from the dentate gyrus were decreased in patients with AH. In the amygdala, we found its left total volume was shrunk, and there was a decrease of its left accessory basal nucleus in patients with AH.</p><p><strong>Conclusions: </strong>We have detected volume alterations of different limbic structures likely due to the presence of AH. The volumes of the right hippocampal tail and left head of the granule cell layer from the dentate gyrus, and total volume of the amygdala and its accessory basal nucleus, were only affected in patients with AH. Bilateral volume alterations in the hippocampal fissure and right fimbria seem inherent of schizophrenia and due to traits not contemplated in our research.</p>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9876563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
University students are particularly vulnerable to mental health issues, with anxiety and depression identified as the most common conditions. During the COVID-19 pandemic, social distancing, self-isolation, and difficulties linked to online teaching and learning have increased their burden of anxiety and depressive symptoms. Thus, the urgent need to intervene in favour of these vulnerable subjects, together with the difficulties in delivering in-person interventions because of lockdowns and restrictions, has led to prioritize digital mental health strategies. This study aimed at systematically reviewing the existing literature on digital mental health interventions targeting anxiety and depressive symptoms in university students during the COVID-19 emergency. Systematic searches of Medline, Embase, and PsycInfo databases identified eight randomized controlled trials. Regarding anxiety symptoms, digitally delivered cognitive behavioural therapy, dialectical behaviour therapy, and mind-body practice techniques emerged as valid strategies, while digital positive psychology and mindfulness-based interventions showed mixed results. On the other hand, digitally delivered dialectical behaviour therapy and positive psychology interventions have shown some efficacy in reducing depressive symptoms. Overall, the available literature, albeit of low quality, seems to support the role of digital interventions in promoting the mental health of university students during the COVID-19 pandemic.
{"title":"Digital mental health interventions for anxiety and depressive symptoms in university students during the COVID-19 pandemic: A systematic review of randomized controlled trials","authors":"Ilaria Riboldi , Daniele Cavaleri , Angela Calabrese , Chiara Alessandra Capogrosso , Susanna Piacenti , Francesco Bartoli , Cristina Crocamo , Giuseppe Carrà","doi":"10.1016/j.rpsm.2022.04.005","DOIUrl":"10.1016/j.rpsm.2022.04.005","url":null,"abstract":"<div><p>University students are particularly vulnerable to mental health issues, with anxiety and depression identified as the most common conditions. During the COVID-19 pandemic, social distancing, self-isolation, and difficulties linked to online teaching and learning have increased their burden of anxiety and depressive symptoms. Thus, the urgent need to intervene in favour of these vulnerable subjects, together with the difficulties in delivering in-person interventions because of lockdowns and restrictions, has led to prioritize digital mental health strategies. This study aimed at systematically reviewing the existing literature on digital mental health interventions targeting anxiety and depressive symptoms in university students during the COVID-19 emergency. Systematic searches of Medline, Embase, and PsycInfo databases identified eight randomized controlled trials. Regarding anxiety symptoms, digitally delivered cognitive behavioural therapy, dialectical behaviour therapy, and mind-body practice techniques emerged as valid strategies, while digital positive psychology and mindfulness-based interventions showed mixed results. On the other hand, digitally delivered dialectical behaviour therapy and positive psychology interventions have shown some efficacy in reducing depressive symptoms. Overall, the available literature, albeit of low quality, seems to support the role of digital interventions in promoting the mental health of university students during the COVID-19 pandemic.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"16 ","pages":"Pages 47-58"},"PeriodicalIF":9.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9785291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.1016/j.rpsm.2022.11.003
Liliana Cruz-Ausejo , David Villarreal-Zegarra , C. Mahony Reátegui-Rivera , Miguel Burgos , Ana L. Vilela-Estrada , Gabriel Castro , Héctor Collantes , Anthony Copez-Lonzoy
Introduction
The COVID-19 pandemic has exacerbated health issues in healthcare workers which in turn impacts their quality of life.
Objective
This review aimed to (i) analyze the impact of the COVID-19 pandemic on the quality of life of healthcare professionals and (ii) identify the associated factors with quality of life.
Materials and methods
We conducted a systematic review using the PRISMA guidelines previously registered in PROSPERO (CRD42021253075). The searched in Web of Science, Scopus, MEDLINE and EMBASE databases included original articles published till May 2021.
Results
We found 19 articles and 14,352 professionals in total, the median age ranged from 29 to 42.5 years and 37% of the studies used the WHOQOL-BREF instrument to assess the outcome. The report was heterogeneous, 7 studies described global scores and 9 by domains. Depression, anxiety and stress were commonly reported factors affecting professional's quality of life and this was significantly lower among professionals working with COVID-19 patients compared to their counterparts.
Conclusion
COVID-19 frontline workers perceived lower quality of life, which was mainly associated with psychological states such as the aforementioned besides to working conditions like not being previously trained in COVID-19 cases. On the other hand, social support, resilience and active coping could improved their quality of life.
简介新冠肺炎大流行加剧了医护人员的健康问题,进而影响了他们的生活质量。目的本综述旨在(i)分析新冠肺炎大流行对医护人员生活质量的影响,(ii)确定与生活质量相关的因素。材料和方法我们使用之前在PROSPERO注册的PRISMA指南(CRD42021253075)进行了系统审查。在Web of Science、Scopus、MEDLINE和EMBASE数据库中搜索到的包括截至2021年5月发表的原创文章。结果我们总共发现了19篇文章和14352名专业人员,中位年龄在29-42.5岁之间,37%的研究使用WHOQOL-BREF工具来评估结果。该报告是异质性的,7项研究描述了全球得分,9项研究按领域分类。据报道,抑郁、焦虑和压力是影响专业人员生活质量的常见因素,与同行相比,从事新冠肺炎患者工作的专业人员的生活质量明显较低。结论COVID-19一线工作人员的生活质量较低,这主要与上述心理状态有关,此外还与工作条件有关,如未接受过COVID-19]病例的培训。另一方面,社会支持、复原力和积极应对可以提高他们的生活质量。
{"title":"The impact of COVID-19 pandemic on the quality of life of healthcare workers and the associated factors: A systematic review","authors":"Liliana Cruz-Ausejo , David Villarreal-Zegarra , C. Mahony Reátegui-Rivera , Miguel Burgos , Ana L. Vilela-Estrada , Gabriel Castro , Héctor Collantes , Anthony Copez-Lonzoy","doi":"10.1016/j.rpsm.2022.11.003","DOIUrl":"10.1016/j.rpsm.2022.11.003","url":null,"abstract":"<div><h3>Introduction</h3><p>The COVID-19 pandemic has exacerbated health issues in healthcare workers which in turn impacts their quality of life.</p></div><div><h3>Objective</h3><p>This review aimed to (i) analyze the impact of the COVID-19 pandemic on the quality of life of healthcare professionals and (ii) identify the associated factors with quality of life.</p></div><div><h3>Materials and methods</h3><p>We conducted a systematic review using the PRISMA guidelines previously registered in PROSPERO (CRD42021253075). The searched in Web of Science, Scopus, MEDLINE and EMBASE databases included original articles published till May 2021.</p></div><div><h3>Results</h3><p>We found 19 articles and 14,352 professionals in total, the median age ranged from 29 to 42.5 years and 37% of the studies used the WHOQOL-BREF instrument to assess the outcome. The report was heterogeneous, 7 studies described global scores and 9 by domains. Depression, anxiety and stress were commonly reported factors affecting professional's quality of life and this was significantly lower among professionals working with COVID-19 patients compared to their counterparts.</p></div><div><h3>Conclusion</h3><p>COVID-19 frontline workers perceived lower quality of life, which was mainly associated with psychological states such as the aforementioned besides to working conditions like not being previously trained in COVID-19 cases. On the other hand, social support, resilience and active coping could improved their quality of life.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"16 ","pages":"Pages 11-24"},"PeriodicalIF":9.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9769413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.1016/j.rpsm.2022.05.008
Marco Colizzi , Maddalena Peghin , Maria De Martino , Giulia Bontempo , Valentina Gerussi , Alvisa Palese , Miriam Isola , Carlo Tascini , Matteo Balestrieri
Introduction
Emerging evidence suggests that mental health symptoms in COVID-19 survivors are higher than expected, possibly indicating that such symptoms are more likely to develop post-infection than just persist as a residual component of the acute phase. It is thus imperative to investigate the potential development of a post-COVID mental health syndrome in the longer-term and identify its risk factors.
Material and methods
A prospective study investigated mental health symptoms associated with COVID-19 and its determinants over a 12-month period following the disease onset in all consecutive adult inpatients and outpatients with COVID-19 attending a tertiary referral hospital from March to May 2020.
Results
A total of 479 patients (female, 52.6%) were followed-up for 12 months after COVID-19 onset. Of them, 47.2% were still presenting with at least one symptom. While most symptoms subsided as compared to COVID-19 onset (all p < 0.001), a significant increase was observed only for symptoms of psychiatric disorders (10.2%) and lack of concentration and focus (20%; all p < 0.001). Patients presenting with symptoms related to multiple body systems 12 months after contracting COVID-19 (all p ≤ 0.034) were more likely to suffer from mental health domain-related symptoms at follow-up. Also, a higher risk of presenting with lack of concentration and focus 12 months post infection was found in those suffering of psychiatric symptoms at COVID-19 onset (p = 0.005).
Conclusions
Findings of this study may have important public health implications, as they underlie the increased need for mental health support in COVID-19 survivors.
{"title":"Mental health symptoms one year after acute COVID-19 infection: Prevalence and risk factors","authors":"Marco Colizzi , Maddalena Peghin , Maria De Martino , Giulia Bontempo , Valentina Gerussi , Alvisa Palese , Miriam Isola , Carlo Tascini , Matteo Balestrieri","doi":"10.1016/j.rpsm.2022.05.008","DOIUrl":"10.1016/j.rpsm.2022.05.008","url":null,"abstract":"<div><h3>Introduction</h3><p>Emerging evidence suggests that mental health symptoms in COVID-19 survivors are higher than expected, possibly indicating that such symptoms are more likely to develop post-infection than just persist as a residual component of the acute phase. It is thus imperative to investigate the potential development of a post-COVID mental health syndrome in the longer-term and identify its risk factors.</p></div><div><h3>Material and methods</h3><p>A prospective study investigated mental health symptoms associated with COVID-19 and its determinants over a 12-month period following the disease onset in all consecutive adult inpatients and outpatients with COVID-19 attending a tertiary referral hospital from March to May 2020.</p></div><div><h3>Results</h3><p>A total of 479 patients (female, 52.6%) were followed-up for 12 months after COVID-19 onset. Of them, 47.2% were still presenting with at least one symptom. While most symptoms subsided as compared to COVID-19 onset (all <em>p</em> <!--><<!--> <!-->0.001), a significant increase was observed only for symptoms of psychiatric disorders (10.2%) and lack of concentration and focus (20%; all <em>p</em> <!--><<!--> <!-->0.001). Patients presenting with symptoms related to multiple body systems 12 months after contracting COVID-19 (all <em>p</em> <!-->≤<!--> <!-->0.034) were more likely to suffer from mental health domain-related symptoms at follow-up. Also, a higher risk of presenting with lack of concentration and focus 12 months post infection was found in those suffering of psychiatric symptoms at COVID-19 onset (<em>p</em> <!-->=<!--> <!-->0.005).</p></div><div><h3>Conclusions</h3><p>Findings of this study may have important public health implications, as they underlie the increased need for mental health support in COVID-19 survivors.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"16 ","pages":"Pages 38-46"},"PeriodicalIF":9.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9785293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.1016/j.rpsm.2022.03.003
Vicent Llorca-Bofí, Marina Adrados-Pérez, Marta Sánchez-Cazalilla, Giovanni Torterolo, Laura Arenas-Pijoan, Esther Buil-Reiné, Eugènia Nicolau-Subires, Carla Albert-Porcar, Lucía Ibarra-Pertusa, Margarita Puigdevall-Ruestes, María Irigoyen-Otiñano
Introduction
The COVID-19 outbreak and lockdown may have an impact in mental health among youth, but reports of psychiatry emergency department encounters in young Spanish population are scarce. The aim of this study is to characterize the reasons for psychiatric urgent care of youth during COVID-19 pandemic in our hospital.
Material and methods
This cross-sectional study compare visits to the psychiatry emergency department and their characteristics in young patients in the province of Lleida before and after the pandemic with special attention to the two states of alarm and suicidal behavior. Information regarding sociodemographic status, chief complaints, diagnosis, characteristics of suicidal behavior, and other data were obtained from the electronic medical records.
Results
Within the total psychiatric emergency attendances, youth patients increased a 83.5% in the second state of alarm (p = 0.001). In this period patients were younger (p = 0.006), had less psychiatric history (p = 0.017) and their living conditions changed with an increase of those living with relatives (p = 0.004). Suicidal ideation care increased without statistical significance (p = 0.073). Multiple logistic regression identifies independent risk factors for suicidal behavior being female (OR: 2.88 [1.39–5.98]), living with relatives (OR: 3.49 [1.43–8.54]), and having a diagnosis of depression (OR: 6.34 [3.58–11.24]).
Conclusions
The number of young people seen in psychiatric emergencies during the chronic stage of the pandemic increased, and these were getting younger and without previous psychiatric contact. The trend to higher rates of suicidal ideation indicates that youth experienced elevated distress during these periods, especially women, living with relatives and presenting depression.
{"title":"Urgent care and suicidal behavior in the child and adolescent population in a psychiatric emergency department in a Spanish province during the two COVID-19 states of alarm","authors":"Vicent Llorca-Bofí, Marina Adrados-Pérez, Marta Sánchez-Cazalilla, Giovanni Torterolo, Laura Arenas-Pijoan, Esther Buil-Reiné, Eugènia Nicolau-Subires, Carla Albert-Porcar, Lucía Ibarra-Pertusa, Margarita Puigdevall-Ruestes, María Irigoyen-Otiñano","doi":"10.1016/j.rpsm.2022.03.003","DOIUrl":"10.1016/j.rpsm.2022.03.003","url":null,"abstract":"<div><h3>Introduction</h3><p>The COVID-19 outbreak and lockdown may have an impact in mental health among youth, but reports of psychiatry emergency department encounters in young Spanish population are scarce. The aim of this study is to characterize the reasons for psychiatric urgent care of youth during COVID-19 pandemic in our hospital.</p></div><div><h3>Material and methods</h3><p>This cross-sectional study compare visits to the psychiatry emergency department and their characteristics in young patients in the province of Lleida before and after the pandemic with special attention to the two states of alarm and suicidal behavior. Information regarding sociodemographic status, chief complaints, diagnosis, characteristics of suicidal behavior, and other data were obtained from the electronic medical records.</p></div><div><h3>Results</h3><p>Within the total psychiatric emergency attendances, youth patients increased a 83.5% in the second state of alarm (<em>p</em> <!-->=<!--> <!-->0.001). In this period patients were younger (<em>p</em> <!-->=<!--> <!-->0.006), had less psychiatric history (<em>p</em> <!-->=<!--> <!-->0.017) and their living conditions changed with an increase of those living with relatives (<em>p</em> <!-->=<!--> <!-->0.004). Suicidal ideation care increased without statistical significance (<em>p</em> <!-->=<!--> <!-->0.073). Multiple logistic regression identifies independent risk factors for suicidal behavior being female (OR: 2.88 [1.39–5.98]), living with relatives (OR: 3.49 [1.43–8.54]), and having a diagnosis of depression (OR: 6.34 [3.58–11.24]).</p></div><div><h3>Conclusions</h3><p>The number of young people seen in psychiatric emergencies during the chronic stage of the pandemic increased, and these were getting younger and without previous psychiatric contact. The trend to higher rates of suicidal ideation indicates that youth experienced elevated distress during these periods, especially women, living with relatives and presenting depression.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"16 ","pages":"Pages 76-83"},"PeriodicalIF":9.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9785294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.1016/j.rpsm.2022.04.004
Borja Pedruzo , Ana Catalan , Claudia Aymerich , Marta Bordenave , Olatz Estevez , Diego Aurofio Gómez , Jon Herrero , María Laborda , Gonzalo Mancebo , Ania Martínez , Malein Pacho , Ana Paniagua , José Luis Pérez , Miguel Ángel González-Torres
Introduction
COVID-19 has spread worldwide since its appearance at the end of 2019. In Spain, 99-day long home confinement was set from March 15th 2020. Previous studies about events requiring situations of isolation suggested that mental health problems may occur among the general population and, more specifically, vulnerable groups such as individuals with serious mental illness (SMI). This study aims to assess the psychological effect of confinement in patients with mental illness admitted to an inpatient psychiatric unit.
Method
In this longitudinal study, IDER (State-Trait Depression Inventory) and STAI (State-Trait Anxiety Inventory) questionnaires were used at two different times (at the beginning and after the lockdown) of the pandemic to evaluate the depression and anxiety symptoms, respectively, in a population of patients who had been previously admitted to the Psychiatry Unit of the Basurto University Hospital.
Results
95 participants completed the IDER questionnaire in the first measurement, with a mean score of 24.56 (SD = 8.18) for state and 23.57 (SD = 8.14) for trait. In the case of STAI, the mean score was 27.86 (SD = 15.19) for the state and 30.49 (SD = 14.71) for the trait. No differences between the first and the second time were found in anxiety and depression levels. People with personality disorders presented high levels of anxiety.
Conclusions
Individuals with a personality disorder showed the highest scores in anxiety and depression. Nevertheless, strict confinement did not affect this population, despite the literature that evidences that the pandemic has worsened people's mental health with SMI.
{"title":"Psychological impact of COVID-19 lockdown on a population with serious mental illness. A prospective cohort study","authors":"Borja Pedruzo , Ana Catalan , Claudia Aymerich , Marta Bordenave , Olatz Estevez , Diego Aurofio Gómez , Jon Herrero , María Laborda , Gonzalo Mancebo , Ania Martínez , Malein Pacho , Ana Paniagua , José Luis Pérez , Miguel Ángel González-Torres","doi":"10.1016/j.rpsm.2022.04.004","DOIUrl":"10.1016/j.rpsm.2022.04.004","url":null,"abstract":"<div><h3>Introduction</h3><p>COVID-19 has spread worldwide since its appearance at the end of 2019. In Spain, 99-day long home confinement was set from March 15th 2020. Previous studies about events requiring situations of isolation suggested that mental health problems may occur among the general population and, more specifically, vulnerable groups such as individuals with serious mental illness (SMI). This study aims to assess the psychological effect of confinement in patients with mental illness admitted to an inpatient psychiatric unit.</p></div><div><h3>Method</h3><p>In this longitudinal study, IDER (State-Trait Depression Inventory) and STAI (State-Trait Anxiety Inventory) questionnaires were used at two different times (at the beginning and after the lockdown) of the pandemic to evaluate the depression and anxiety symptoms, respectively, in a population of patients who had been previously admitted to the Psychiatry Unit of the Basurto University Hospital.</p></div><div><h3>Results</h3><p>95 participants completed the IDER questionnaire in the first measurement, with a mean score of 24.56 (SD<!--> <!-->=<!--> <!-->8.18) for state and 23.57 (SD<!--> <!-->=<!--> <!-->8.14) for trait. In the case of STAI, the mean score was 27.86 (SD<!--> <!-->=<!--> <!-->15.19) for the state and 30.49 (SD<!--> <!-->=<!--> <!-->14.71) for the trait. No differences between the first and the second time were found in anxiety and depression levels. People with personality disorders presented high levels of anxiety.</p></div><div><h3>Conclusions</h3><p>Individuals with a personality disorder showed the highest scores in anxiety and depression. Nevertheless, strict confinement did not affect this population, despite the literature that evidences that the pandemic has worsened people's mental health with SMI.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"16 ","pages":"Pages 59-67"},"PeriodicalIF":9.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9416636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.1016/j.rpsm.2022.08.001
Manuel Canal-Rivero , Cristian Montes-García , Nathalia Garrido-Torres , Amanda Moreno-Mellado , Pablo Reguera-Pozuelo , Miguel Ruiz-Veguilla , Benedicto Crespo-Facorro
Introduction
Health care workers (HCW) have been identified as a risk group to suffer psychological burden derived from Coronavirus Disease 19 (COVID-19) pandemic. In addition, possible gender differences in the emotional reactions derived from COVID-19 pandemic have been suggested in this population. The aims of the study were to explore the impact of COVID-19 as well as possible gender differences on mental health status and suicidality in a cohort of HCW.
Materials and methods
One thousand four hundred and thirty-two HCW responded to an online survey including sociodemographic, clinical, and psychometric tests in May 2020 while 251 HCW answered in November 2020. Mental health status was measured by General Health Questionnaire 28 (GHQ-28) in both time periods.
Results
HCW informed of a worsening in somatic symptomatology over the follow up period. Gender differences were found in all GHQ-28 dimensions as well in the total score of the questionnaire. Post hoc analyses displayed significant interaction between the time and gender in somatic and anxiety dimensions as well as in GHQ-28 total score. Stress produced by COVID-19 spreading and the feeling of being overwhelmed at work resulted the main predictors of psychological distress although each domain is characterized by a specific set of predictors.
Conclusions
Somatic reactions represent the most sensitive dimension over the follow-up period. Moreover, women are characterized by a greater psychological distress at the beginning, although these differences tend to disappear over time. Finally, a complex network of factors predicted different dimensions of psychological distress, showing the complexity of prevention in high-risk populations facing major disasters.
{"title":"The impact of COVID-19 pandemic on the psychological well-being among health care workers: A 6-month cohort longitudinal survey study","authors":"Manuel Canal-Rivero , Cristian Montes-García , Nathalia Garrido-Torres , Amanda Moreno-Mellado , Pablo Reguera-Pozuelo , Miguel Ruiz-Veguilla , Benedicto Crespo-Facorro","doi":"10.1016/j.rpsm.2022.08.001","DOIUrl":"10.1016/j.rpsm.2022.08.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Health care workers (HCW) have been identified as a risk group to suffer psychological burden derived from Coronavirus Disease 19 (COVID-19) pandemic. In addition, possible gender differences in the emotional reactions derived from COVID-19 pandemic have been suggested in this population. The aims of the study were to explore the impact of COVID-19 as well as possible gender differences on mental health status and suicidality in a cohort of HCW.</p></div><div><h3>Materials and methods</h3><p>One thousand four hundred and thirty-two HCW responded to an online survey including sociodemographic, clinical, and psychometric tests in May 2020 while 251 HCW answered in November 2020. Mental health status was measured by General Health Questionnaire 28 (GHQ-28) in both time periods.</p></div><div><h3>Results</h3><p>HCW informed of a worsening in somatic symptomatology over the follow up period. Gender differences were found in all GHQ-28 dimensions as well in the total score of the questionnaire. Post hoc analyses displayed significant interaction between the time and gender in somatic and anxiety dimensions as well as in GHQ-28 total score. Stress produced by COVID-19 spreading and the feeling of being overwhelmed at work resulted the main predictors of psychological distress although each domain is characterized by a specific set of predictors.</p></div><div><h3>Conclusions</h3><p>Somatic reactions represent the most sensitive dimension over the follow-up period. Moreover, women are characterized by a greater psychological distress at the beginning, although these differences tend to disappear over time. Finally, a complex network of factors predicted different dimensions of psychological distress, showing the complexity of prevention in high-risk populations facing major disasters.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"16 ","pages":"Pages 25-37"},"PeriodicalIF":9.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9416651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.1016/j.rpsm.2022.12.002
Ana Viejo Casas , Marcos Gómez-Revuelta , Urko Merino Garay , Francisco Ruiz Guerrero , Mario Ruiz Núñez , Patricia Fernández Solla , Roberto Garrastazu López , Juan Carlos López Caro , Elsa García Rumayor , Laura Boada Antón , María Juncal Ruiz , Víctor Ortiz-García de la Foz , Javier Vázquez-Bourgon
Background
COVID-19 pandemic has affected the mental health of the general population, and in particular of health professionals. Primary care personnel are at greater risk due to being highly exposed to the disease and working regularly in direct contact with patients suffering COVID-19. However, there is not sufficient evidence on the long-term psychological impact these professionals may suffer. We aimed to explore the long-term psychological impact of COVID-19 on primary care professionals.
Methods
We applied a two-phase design; a self-reported psychopathology screening (PHQ-9, GAD-7, ISI and IES-R) in phase-1, and a specialised psychiatric evaluation (MINI, HDRS and STAI) in phase-2 to confirm phase-1 results. Evaluations were carried at the beginning of the pandemic (May–June 2020) (n = 410) and one year later (n = 339). Chi-square, ANOVA and logistic regression tests were used for statistical analyses.
Results
Primary care professionals presented high rates of depression, anxiety and psychological distress, measured by PHQ-9, GAD-7 and IES-R respectively, during the pandemic. Depressive symptoms’ severity (PHQ-9: 7.5 vs 8.4, p = 0.013) increased after one year of COVID-19 pandemic. After one year nearly 40% of subjects presented depression. Being women, having suffered COVID-19 or a relative with COVID-19, and being a front-line professional were risk factors for presenting depression and anxiety.
Conclusion
Primary Care professionals in Cantabria present a poor mental health during COVID-19 pandemic, which has even worsened at long-term, presenting a greater psychopathology severity one year after. Thus, it is critical implementing prevention and early-treatment programmes to help these essential professionals to cope with the pandemic.
背景新冠肺炎疫情影响了普通人群的心理健康,尤其是卫生专业人员的心理健康。初级保健人员面临更大的风险,因为他们高度接触这种疾病,并定期与新冠肺炎患者直接接触。然而,没有足够的证据表明这些专业人员可能会遭受长期的心理影响。我们旨在探讨新冠肺炎对初级保健专业人员的长期心理影响。方法采用两阶段设计;在第一阶段进行自我报告的精神病理学筛查(PHQ-9、GAD-7、ISI和IES-R),在第二阶段进行专门的精神病学评估(MINI、HDRS和STAI),以确认第一阶段的结果。在大流行开始时(2020年5月至6月)(n=410)和一年后(n=339)进行了评估。采用卡方检验、方差分析和逻辑回归检验进行统计分析。结果在疫情期间,初级保健专业人员的抑郁、焦虑和心理困扰发生率较高,PHQ-9、GAD-7和IES-R分别测定。新冠肺炎大流行一年后,抑郁症状的严重程度(PHQ-9:7.5 vs 8.4,p=0.013)增加。一年后,近40%的受试者出现抑郁症。女性、患有新冠肺炎或患有新冠肺炎的亲属以及一线专业人员是出现抑郁和焦虑的危险因素。结论新冠肺炎大流行期间,坎塔布里亚初级保健专业人员的心理健康状况较差,长期来看甚至恶化,一年后表现出更严重的精神病理学。因此,至关重要的是实施预防和早期治疗方案,以帮助这些重要的专业人员应对疫情。
{"title":"Long-term mental health impact of COVID-19 on primary care health workers in northern Spain: Results from a two-phase longitudinal study","authors":"Ana Viejo Casas , Marcos Gómez-Revuelta , Urko Merino Garay , Francisco Ruiz Guerrero , Mario Ruiz Núñez , Patricia Fernández Solla , Roberto Garrastazu López , Juan Carlos López Caro , Elsa García Rumayor , Laura Boada Antón , María Juncal Ruiz , Víctor Ortiz-García de la Foz , Javier Vázquez-Bourgon","doi":"10.1016/j.rpsm.2022.12.002","DOIUrl":"10.1016/j.rpsm.2022.12.002","url":null,"abstract":"<div><h3>Background</h3><p>COVID-19 pandemic has affected the mental health of the general population, and in particular of health professionals. Primary care personnel are at greater risk due to being highly exposed to the disease and working regularly in direct contact with patients suffering COVID-19. However, there is not sufficient evidence on the long-term psychological impact these professionals may suffer. We aimed to explore the long-term psychological impact of COVID-19 on primary care professionals.</p></div><div><h3>Methods</h3><p>We applied a two-phase design; a self-reported psychopathology screening (PHQ-9, GAD-7, ISI and IES-R) in phase-1, and a specialised psychiatric evaluation (MINI, HDRS and STAI) in phase-2 to confirm phase-1 results. Evaluations were carried at the beginning of the pandemic (May–June 2020) (<em>n</em> <!-->=<!--> <!-->410) and one year later (<em>n</em> <!-->=<!--> <!-->339). Chi-square, ANOVA and logistic regression tests were used for statistical analyses.</p></div><div><h3>Results</h3><p>Primary care professionals presented high rates of depression, anxiety and psychological distress, measured by PHQ-9, GAD-7 and IES-R respectively, during the pandemic. Depressive symptoms’ severity (PHQ-9: 7.5 vs 8.4, <em>p</em> <!-->=<!--> <!-->0.013) increased after one year of COVID-19 pandemic. After one year nearly 40% of subjects presented depression. Being women, having suffered COVID-19 or a relative with COVID-19, and being a front-line professional were risk factors for presenting depression and anxiety.</p></div><div><h3>Conclusion</h3><p>Primary Care professionals in Cantabria present a poor mental health during COVID-19 pandemic, which has even worsened at long-term, presenting a greater psychopathology severity one year after. Thus, it is critical implementing prevention and early-treatment programmes to help these essential professionals to cope with the pandemic.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"16 ","pages":"Pages 1-10"},"PeriodicalIF":9.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9495064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.1016/j.rpsm.2022.03.004
María Irigoyen-Otiñano , Eugènia Nicolau-Subires , Ana González-Pinto , Marina Adrados-Pérez , Esther Buil-Reiné , Lucía Ibarra-Pertusa , Carla Albert-Porcar , Laura Arenas-Pijoan , Marta Sánchez-Cazalilla , Giovanni Torterolo , Margarita Puigdevall-Ruestes , Vicent Llorca-Bofí
Introduction
Different studies have suggested that psychological, social and economic factors could contribute to an increase in the suicide. That is why the scientific community fear an epidemic of suicides secondary to this crisis. The objective is to evaluate the variables related to suicidal behavior during the two states of alarm and to review if there were sociodemographic or clinical differences with respect to periods prior to the COVID-19 pandemic.
Material and methods
We compared visits to the emergency room and their characteristics of all patients with suicidal behavior before and after the pandemic in Lérida. Information on sociodemographic status, reason for consultation, diagnosis and characteristics of suicidal behavior was obtained from the electronic medical record.
Results
No differences were observed in the percentage of suicidal ideation or attempts in the three periods (p = 0.201). The characteristics in the multiple logistic regression associated with suicidal behavior are: being a woman (OR: 1.81 [1.27–2.56]), living with relatives (OR: 1.55 [1.05–2.32]) and have a diagnosis of non-alcohol related substance use disorder (OR: 1.94 [1.09–3.42]). As protective factors, being visited in the emergency room during the second state of alarm (OR: 0.68 [0.48–0.96]) and having depression (OR: 0.67 [0.47–0.96]).
Conclusions
Emergency care for suicidal behavior did not increase during the pandemic and, in fact, in 2020 completed suicides decreased by almost half in the province. Risk factors for suicide attempt were female gender, living with relatives, and having a substance use disorder diagnosis. Instead, depression was a protective factor.
{"title":"Characteristics of patients treated for suicidal behavior during the pandemic in a psychiatric emergency department in a Spanish province","authors":"María Irigoyen-Otiñano , Eugènia Nicolau-Subires , Ana González-Pinto , Marina Adrados-Pérez , Esther Buil-Reiné , Lucía Ibarra-Pertusa , Carla Albert-Porcar , Laura Arenas-Pijoan , Marta Sánchez-Cazalilla , Giovanni Torterolo , Margarita Puigdevall-Ruestes , Vicent Llorca-Bofí","doi":"10.1016/j.rpsm.2022.03.004","DOIUrl":"10.1016/j.rpsm.2022.03.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Different studies have suggested that psychological, social and economic factors could contribute to an increase in the suicide. That is why the scientific community fear an epidemic of suicides secondary to this crisis. The objective is to evaluate the variables related to suicidal behavior during the two states of alarm and to review if there were sociodemographic or clinical differences with respect to periods prior to the COVID-19 pandemic.</p></div><div><h3>Material and methods</h3><p>We compared visits to the emergency room and their characteristics of all patients with suicidal behavior before and after the pandemic in Lérida. Information on sociodemographic status, reason for consultation, diagnosis and characteristics of suicidal behavior was obtained from the electronic medical record.</p></div><div><h3>Results</h3><p>No differences were observed in the percentage of suicidal ideation or attempts in the three periods (<em>p</em> <!-->=<!--> <!-->0.201). The characteristics in the multiple logistic regression associated with suicidal behavior are: being a woman (OR: 1.81 [1.27–2.56]), living with relatives (OR: 1.55 [1.05–2.32]) and have a diagnosis of non-alcohol related substance use disorder (OR: 1.94 [1.09–3.42]). As protective factors, being visited in the emergency room during the second state of alarm (OR: 0.68 [0.48–0.96]) and having depression (OR: 0.67 [0.47–0.96]).</p></div><div><h3>Conclusions</h3><p>Emergency care for suicidal behavior did not increase during the pandemic and, in fact, in 2020 completed suicides decreased by almost half in the province. Risk factors for suicide attempt were female gender, living with relatives, and having a substance use disorder diagnosis. Instead, depression was a protective factor.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"16 ","pages":"Pages 68-75"},"PeriodicalIF":9.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10189561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}