首页 > 最新文献

Revista de psiquiatria y salud mental最新文献

英文 中文
Incidencia de esquizofrenia en España: más preguntas que certezas 西班牙精神分裂症的发病率:问题多于肯定
IF 9.2 3区 医学 Q1 PSYCHIATRY Pub Date : 2022-01-01 DOI: 10.1016/j.rpsm.2021.05.002
Víctor Romero-Pardo , Franco Mascayano , Ezra S. Susser , Gonzalo Martínez-Alés
{"title":"Incidencia de esquizofrenia en España: más preguntas que certezas","authors":"Víctor Romero-Pardo , Franco Mascayano , Ezra S. Susser , Gonzalo Martínez-Alés","doi":"10.1016/j.rpsm.2021.05.002","DOIUrl":"10.1016/j.rpsm.2021.05.002","url":null,"abstract":"","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"15 1","pages":"Pages 61-62"},"PeriodicalIF":9.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989121000598/pdfft?md5=da326fd6903ec757ec10ea9dfcbae75d&pid=1-s2.0-S1888989121000598-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39014724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Estudio en imagen en espejo (10 años de seguimiento y 10 de pretratamiento estándar) de ingresos hospitalarios de personas con esquizofrenia grave en un programa comunitario con gestión de casos 社区病例管理项目中严重精神分裂症患者住院的镜像研究(10年随访和10年标准治疗前)
IF 9.2 3区 医学 Q1 PSYCHIATRY Pub Date : 2022-01-01 DOI: 10.1016/j.rpsm.2019.04.004
Silvia Díaz-Fernández , Danny Francisco Frías-Ortiz , Juan José Fernández-Miranda

Objectives

To determine the psychiatric hospitalizations of patients with severe schizophrenia before (standard treatment in mental health centres) and during treatment in a comprehensive, community-based, case- managed programme, as well as the role played by antipsychotic medication (oral or long-acting injectable).

Method

Observational, mirror image study of ten years of follow-up and ten retrospectives (‘pre-treatment’: standard), of patients with severe schizophrenia in a community-based programme, with pharmacological and psychosocial integrated treatment and intensive case management (n = 344). Reasons for discharge from the programme and psychiatric hospital admissions (and whether they were involuntary) were recorded ten years before and during treatment, as well as the antipsychotic medication prescribed.

Results

The retention achieved in the programme was high: after 10 years only 12.2% of the patients were voluntary discharges vs 84.3% on previous standard treatment. The number of patients with hospital admissions, and number of admissions due to relapses decreased drastically after entering the programme (p < 0,0001), as well the involuntary admissions (p < 0,001). Being on long-acting injectable antipsychotic medication was related with these results (p < 0,0001).

Conclusions

Treatment of patients with severe schizophrenia in a comprehensive, community-based and case-managed programme achieved high retention rates, and was effective in drastically reducing psychiatric hospitalizations compared to the previous standard treatment in mental health units. Undergoing treatment with long-acting injectable antipsychotics was clearly linked to these outcomes.

目的了解重度精神分裂症患者在精神卫生中心标准治疗前和在综合、社区、病例管理方案治疗期间的精神住院情况,以及抗精神病药物(口服或长效注射)的作用。方法:观察性镜像研究,10年随访和10年回顾性研究(“治疗前”:标准),在一个以社区为基础的方案中,采用药物和社会心理综合治疗和强化病例管理(n = 344)。在治疗前和治疗期间,记录了出院的原因和精神病医院的入院情况(以及是否非自愿),并记录了处方的抗精神病药物。结果该方案的保留率很高:10年后,只有12.2%的患者自愿出院,而以前的标准治疗为84.3%。参加该方案后,入院的病人人数和因复发而入院的人数急剧减少(p <2001),以及非自愿入院(p <0001)。服用长效注射抗精神病药物与这些结果有关(p <0, 0001)。结论:以社区为基础、病例管理的综合治疗方案对严重精神分裂症患者的治疗取得了很高的保留率,与之前在精神卫生单位的标准治疗相比,有效地大大减少了精神病学住院率。接受长效注射抗精神病药物治疗显然与这些结果有关。
{"title":"Estudio en imagen en espejo (10 años de seguimiento y 10 de pretratamiento estándar) de ingresos hospitalarios de personas con esquizofrenia grave en un programa comunitario con gestión de casos","authors":"Silvia Díaz-Fernández ,&nbsp;Danny Francisco Frías-Ortiz ,&nbsp;Juan José Fernández-Miranda","doi":"10.1016/j.rpsm.2019.04.004","DOIUrl":"10.1016/j.rpsm.2019.04.004","url":null,"abstract":"<div><h3>Objectives</h3><p>To determine the psychiatric hospitalizations of patients with severe schizophrenia before (standard treatment in mental health centres) and during treatment in a comprehensive, community-based, case- managed programme, as well as the role played by antipsychotic medication (oral or long-acting injectable).</p></div><div><h3>Method</h3><p>Observational, mirror image study of ten years of follow-up and ten retrospectives (‘pre-treatment’: standard), of patients with severe schizophrenia in a community-based programme, with pharmacological and psychosocial integrated treatment and intensive case management (n<!--> <!-->=<!--> <!-->344). Reasons for discharge from the programme and psychiatric hospital admissions (and whether they were involuntary) were recorded ten years before and during treatment, as well as the antipsychotic medication prescribed.</p></div><div><h3>Results</h3><p>The retention achieved in the programme was high: after 10 years only 12.2% of the patients were voluntary discharges vs 84.3% on previous standard treatment. The number of patients with hospital admissions, and number of admissions due to relapses decreased drastically after entering the programme (p<!--> <!-->&lt;<!--> <!-->0,0001), as well the involuntary admissions (p<!--> <!-->&lt;<!--> <!-->0,001). Being on long-acting injectable antipsychotic medication was related with these results (p<!--> <!-->&lt;<!--> <!-->0,0001).</p></div><div><h3>Conclusions</h3><p>Treatment of patients with severe schizophrenia in a comprehensive, community-based and case-managed programme achieved high retention rates, and was effective in drastically reducing psychiatric hospitalizations compared to the previous standard treatment in mental health units. Undergoing treatment with long-acting injectable antipsychotics was clearly linked to these outcomes.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"15 1","pages":"Pages 47-53"},"PeriodicalIF":9.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989119300527/pdfft?md5=8aebdbc9ada1af6883807feeeac631dc&pid=1-s2.0-S1888989119300527-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37368979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Early versus late risk factors for deficit and nondeficit schizophrenia 缺乏性和非缺乏性精神分裂症的早期和晚期危险因素
IF 9.2 3区 医学 Q1 PSYCHIATRY Pub Date : 2022-01-01 DOI: 10.1016/j.rpsm.2021.03.002
Setareh Alabaf , Brian Kirkpatrick , Shanquan Chen , Rudolf N. Cardinal , Emilio Fernandez-Egea

Aim

We examined whether timing of known risk factors for schizophrenia may influence the development of schizophrenia with primary negative symptoms.

Method

This cross-sectional single-centre study in England used a clinical cohort of 167 clozapine-treated schizophrenia patients. Deficit and nondeficit schizophrenia models were used as clinical proxies of patients with and without primary negative symptoms respectively. Patients were assessed using the Schedule for the Deficit Syndrome. We examined previously replicated risk factors (family history of psychosis, advanced paternal age, male gender, birth weight <3000 g, summer birth, cannabis use, exposure to physical or sexual abuse and/or bullying) as well as other traumatic events for deficit and nondeficit schizophrenia.

Results

We found a distinct risk factor pattern for the two groups. Compared to the nondeficit group, patients with deficit schizophrenia reported a significantly lower prevalence of cannabis use (p = 0.005) at the time of first-episode psychosis (FEP), physical or sexual abuse (p = 0.033) prior to FEP, less exposure to crime-related traumatic events (p = 0.012) and significantly associated with summer birth (p = 0.017). The groups did not differ in terms of family history of psychosis, advanced paternal age, male gender, or low birth weight. To account for multiple comparisons, a confirmatory analysis was performed using logistic regression which yielded similar results except that summer birth no longer reached statistical significance.

Conclusion

Our results suggest the timing of the insult may influence the symptom presentation, with insults later in life (cannabis or traumatic events) being associated with psychotic presentation and less with primary negative symptoms.

我们研究了已知的精神分裂症危险因素的时间是否会影响原发阴性症状的精神分裂症的发展。方法在英国进行的一项横断面单中心研究纳入了167例氯氮平治疗的精神分裂症患者的临床队列。以有原发性阴性症状和无原发性阴性症状的精神分裂症患者分别采用缺陷型和非缺陷型精神分裂症模型作为临床指标。采用缺陷综合征量表对患者进行评估。我们检查了先前重复的风险因素(精神病家族史、父亲高龄、男性、出生体重(3000克)、夏季出生、大麻使用、遭受身体或性虐待和/或欺凌)以及其他创伤性事件对缺陷和非缺陷精神分裂症的影响。结果我们发现两组患者有明显的危险因素模式。与非缺陷组相比,缺陷精神分裂症患者在首次精神病发作(FEP)时使用大麻的患病率(p = 0.005),在FEP之前遭受身体或性虐待(p = 0.033),较少接触与犯罪相关的创伤事件(p = 0.012),并与夏季出生显著相关(p = 0.017)。两组在精神病家族史、父亲年龄、男性性别或低出生体重方面没有差异。为了解释多重比较,使用逻辑回归进行了验证性分析,除了夏季出生不再达到统计显著性外,结果相似。结论:我们的研究结果表明,侮辱的时间可能会影响症状的表现,晚年的侮辱(大麻或创伤事件)与精神病症状的表现有关,而与原发性阴性症状的关系较小。
{"title":"Early versus late risk factors for deficit and nondeficit schizophrenia","authors":"Setareh Alabaf ,&nbsp;Brian Kirkpatrick ,&nbsp;Shanquan Chen ,&nbsp;Rudolf N. Cardinal ,&nbsp;Emilio Fernandez-Egea","doi":"10.1016/j.rpsm.2021.03.002","DOIUrl":"10.1016/j.rpsm.2021.03.002","url":null,"abstract":"<div><h3>Aim</h3><p>We examined whether timing of known risk factors for schizophrenia may influence the development of schizophrenia with primary negative symptoms.</p></div><div><h3>Method</h3><p>This cross-sectional single-centre study in England used a clinical cohort of 167 clozapine-treated schizophrenia patients. Deficit and nondeficit schizophrenia models were used as clinical proxies of patients with and without primary negative symptoms respectively. Patients were assessed using the Schedule for the Deficit Syndrome. We examined previously replicated risk factors (family history of psychosis, advanced paternal age, male gender, birth weight &lt;3000<!--> <!-->g, summer birth, cannabis use, exposure to physical or sexual abuse and/or bullying) as well as other traumatic events for deficit and nondeficit schizophrenia.</p></div><div><h3>Results</h3><p>We found a distinct risk factor pattern for the two groups. Compared to the nondeficit group, patients with deficit schizophrenia reported a significantly lower prevalence of cannabis use (<em>p</em> <!-->=<!--> <!-->0.005) at the time of first-episode psychosis (FEP), physical or sexual abuse (<em>p</em> <!-->=<!--> <!-->0.033) prior to FEP, less exposure to crime-related traumatic events (<em>p</em> <!-->=<!--> <!-->0.012) and significantly associated with summer birth (<em>p</em> <!-->=<!--> <!-->0.017). The groups did not differ in terms of family history of psychosis, advanced paternal age, male gender, or low birth weight. To account for multiple comparisons, a confirmatory analysis was performed using logistic regression which yielded similar results except that summer birth no longer reached statistical significance.</p></div><div><h3>Conclusion</h3><p>Our results suggest the timing of the insult may influence the symptom presentation, with insults later in life (cannabis or traumatic events) being associated with psychotic presentation and less with primary negative symptoms.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"15 1","pages":"Pages 38-46"},"PeriodicalIF":9.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989121000331/pdfft?md5=a1c6aa9ce7c5d2e9751d2abee415eb9a&pid=1-s2.0-S1888989121000331-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25556291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Negative Symptoms: A Brief Story and Advances in Spain 阴性症状:一个简短的故事和进展在西班牙
IF 9.2 3区 医学 Q1 PSYCHIATRY Pub Date : 2022-01-01 DOI: 10.1016/j.rpsm.2022.01.001
William T. Carpenter Jr
{"title":"Negative Symptoms: A Brief Story and Advances in Spain","authors":"William T. Carpenter Jr","doi":"10.1016/j.rpsm.2022.01.001","DOIUrl":"10.1016/j.rpsm.2022.01.001","url":null,"abstract":"","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"15 1","pages":"Pages 1-2"},"PeriodicalIF":9.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989122000222/pdfft?md5=f11c1524592bca09fe0c68780814b8d2&pid=1-s2.0-S1888989122000222-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75139333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Validation of a European Spanish adaptation of the Apathy Evaluation Scale-self-rated version (AES-S) in patients with schizophrenia 精神分裂症患者冷漠评估量表自评版(AES-S)的欧洲西班牙改编的验证
IF 9.2 3区 医学 Q1 PSYCHIATRY Pub Date : 2022-01-01 DOI: 10.1016/j.rpsm.2020.04.008
Clara Martínez-Cao , Leticia García-Álvarez , Teresa Bobes-Bascarán , Lorena de la Fuente-Tomás , Emilio Fernández-Egea , Ángela Velasco , Leticia González-Blanco , Paula Zurrón-Madera , Eduardo Fonseca-Pedrero , Pilar A. Sáiz-Martínez , María Paz García-Portilla , Julio Bobes

Introduction

Apathy is a negative symptom of schizophrenia and is associated with poor real world functioning. Therefore, it is important to have validated psychometric instruments to assess this symptom. This is the first study to validate the Spanish adaptation of the self-rated version of the Apathy Assessment Scale (AES-S) in patients with schizophrenia.

Materials and methods

Naturalistic, cross-sectional, validation study in 104 patients with schizophrenia evaluated using the following scales: Clinical Global Impression-Severity (CGI-S), Personal and Social Performance (PSP), Clinical Assessment Interview for Negative Symptoms (CAINS), Self-report of Negative Symptoms (SNS), Motivation and Pleasure Scale-Self-Report (MAP-SR), Calgary Depression Scale for Schizophrenia (CDSS), and Apathy Evaluation Scale-self-rated version (AES-S).

Results

Reliability: Internal consistency (Cronbach's alpha) was 0.908. Convergent validity: The Pearson correlation coefficient between AES-S and CAINS-MAP total scores was −0.483 (p < 0.001). For SNS, total and avolition subscale scores were −0.803 and −0.639 (p < 0.001), respectively. With the MAP-SR, the correlation coefficient was −0.727 (p < 0.001). Divergent validity: The Pearson correlation coefficient between AES-S and PSP total scores was 0.504 (p < 0.001). Furthermore, with the CDSS, the correlation coefficient was −0.431 (p < 0.001). Discriminant validity: The AES-S discriminated between different levels of illness severity according to CGI-S scores. Factor analysis: A three-component solution explained 57.32% of the variance. Pearson correlations between coefficients were 1–2 = 0.265, 1–3 = 0.464, and 2–3 = 0.060.

Conclusion

The Spanish AES-S is a reliable and valid instrument for assessing apathy in Spanish patients with schizophrenia. It seems to be appropriate for use in everyday clinical practice as a means of monitoring apathy in these patients.

冷漠是精神分裂症的一种阴性症状,与现实生活功能低下有关。因此,重要的是要有有效的心理测量工具来评估这种症状。这是第一个验证西班牙语自评版冷漠评估量表(AES-S)在精神分裂症患者中的适应性的研究。材料与方法对104例精神分裂症患者进行自然、横断面、验证性研究,采用以下量表进行评估:临床总体印象-严重程度(ci -s)、个人与社会表现(PSP)、阴性症状临床评估访谈(CAINS)、阴性症状自述(SNS)、动机与愉悦量表-自述(MAP-SR)、精神分裂症卡尔加里抑郁量表(CDSS)和冷漠评估量表-自评版(AES-S)。结果信度:内部一致性(Cronbach’s alpha)为0.908。收敛效度:AES-S总分与CAINS-MAP总分的Pearson相关系数为- 0.483 (p <0.001)。SNS的总分和自愿分分别为- 0.803分和- 0.639分(p <分别为0.001)。MAP-SR的相关系数为- 0.727 (p <0.001)。发散效度:AES-S与PSP总分的Pearson相关系数为0.504 (p <0.001)。此外,与CDSS相关系数为- 0.431 (p <0.001)。区分效度:AES-S根据CGI-S评分区分不同程度的疾病严重程度。因子分析:三组分解决方案解释了57.32%的方差。系数间Pearson相关性为1-2 = 0.265,1-3 = 0.464,2-3 = 0.060。结论西班牙AES-S量表是一种可靠、有效的评估西班牙精神分裂症患者冷漠程度的工具。它似乎适合在日常临床实践中使用,作为监测这些患者冷漠的手段。
{"title":"Validation of a European Spanish adaptation of the Apathy Evaluation Scale-self-rated version (AES-S) in patients with schizophrenia","authors":"Clara Martínez-Cao ,&nbsp;Leticia García-Álvarez ,&nbsp;Teresa Bobes-Bascarán ,&nbsp;Lorena de la Fuente-Tomás ,&nbsp;Emilio Fernández-Egea ,&nbsp;Ángela Velasco ,&nbsp;Leticia González-Blanco ,&nbsp;Paula Zurrón-Madera ,&nbsp;Eduardo Fonseca-Pedrero ,&nbsp;Pilar A. Sáiz-Martínez ,&nbsp;María Paz García-Portilla ,&nbsp;Julio Bobes","doi":"10.1016/j.rpsm.2020.04.008","DOIUrl":"10.1016/j.rpsm.2020.04.008","url":null,"abstract":"<div><h3>Introduction</h3><p>Apathy is a negative symptom of schizophrenia and is associated with poor real world functioning. Therefore, it is important to have validated psychometric instruments to assess this symptom. This is the first study to validate the Spanish adaptation of the self-rated version of the Apathy Assessment Scale (AES-S) in patients with schizophrenia.</p></div><div><h3>Materials and methods</h3><p>Naturalistic, cross-sectional, validation study in 104 patients with schizophrenia evaluated using the following scales: Clinical Global Impression-Severity (CGI-S), Personal and Social Performance (PSP), Clinical Assessment Interview for Negative Symptoms (CAINS), Self-report of Negative Symptoms (SNS), Motivation and Pleasure Scale-Self-Report (MAP-SR), Calgary Depression Scale for Schizophrenia (CDSS), and Apathy Evaluation Scale-self-rated version (AES-S).</p></div><div><h3>Results</h3><p>Reliability: Internal consistency (Cronbach's alpha) was 0.908. Convergent validity: The Pearson correlation coefficient between AES-S and CAINS-MAP total scores was −0.483 (<em>p</em> <!-->&lt;<!--> <!-->0.001). For SNS, total and avolition subscale scores were −0.803 and −0.639 (<em>p</em> <!-->&lt;<!--> <!-->0.001), respectively. With the MAP-SR, the correlation coefficient was −0.727 (<em>p</em> <!-->&lt;<!--> <!-->0.001). Divergent validity: The Pearson correlation coefficient between AES-S and PSP total scores was 0.504 (<em>p</em> <!-->&lt;<!--> <!-->0.001). Furthermore, with the CDSS, the correlation coefficient was −0.431 (<em>p</em> <!-->&lt;<!--> <!-->0.001). Discriminant validity: The AES-S discriminated between different levels of illness severity according to CGI-S scores. Factor analysis: A three-component solution explained 57.32% of the variance. Pearson correlations between coefficients were 1–2<!--> <!-->=<!--> <!-->0.265, 1–3<!--> <!-->=<!--> <!-->0.464, and 2–3<!--> <!-->=<!--> <!-->0.060.</p></div><div><h3>Conclusion</h3><p>The Spanish AES-S is a reliable and valid instrument for assessing apathy in Spanish patients with schizophrenia. It seems to be appropriate for use in everyday clinical practice as a means of monitoring apathy in these patients.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"15 1","pages":"Pages 22-28"},"PeriodicalIF":9.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989120300331/pdfft?md5=3d48a2cba476908b299b235cf261095d&pid=1-s2.0-S1888989120300331-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38017848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Efectos del trauma infantil en el reconocimiento de la expresión facial de miedo en psicosis 儿童创伤对精神病患者恐惧面部表情识别的影响
IF 9.2 3区 医学 Q1 PSYCHIATRY Pub Date : 2022-01-01 DOI: 10.1016/j.rpsm.2019.01.005
Antía Brañas , Guillermo Lahera , María Luisa Barrigón , Manuel Canal-Rivero , Miguel Ruiz-Veguilla

Introduction

Childhood trauma has been reported as a risk factor for psychosis. Different types of traumatic experiences in childhood could lead to different clinical manifestations in psychotic disorders.

Material and methods

We studied differences in social cognition (emotion recognition and theory of mind) and clinical symptoms in a sample of 62 patients with psychosis (less than 5 years of illness) and childhood trauma, analysing performance by trauma type.

Results

Psychotic patients with a history of childhood trauma other than sexual abuse were more capable of recognizing fear as a facial emotion (especially when facial stimuli were non-degraded) than participants with a history of sexual abuse or with no history of childhood trauma (P = .008). We also found that the group that had suffered sexual abuse did not show improvement in fear recognition when exposed to clearer stimuli, although this intergroup difference did not reach statistical significance (P = .064). We have not found other differences between abuse groups, neither in clinical symptoms (PANSS factors) nor in Hinting Task scores.

Conclusion

We have found differences in fear recognition among patients with psychotic disorders who have experienced different types of childhood trauma.

据报道,童年创伤是精神病的一个危险因素。不同类型的童年创伤经历可能导致不同的精神障碍临床表现。材料与方法我们研究了62例精神病患者(发病未满5年)和儿童期创伤患者的社会认知(情绪识别和心理理论)和临床症状的差异,并按创伤类型分析其表现。结果有儿童期创伤史(非性虐待)的精神病患者比有儿童期创伤史或无儿童期创伤史的患者更能识别恐惧为面部情绪(特别是当面部刺激非退化时)(P = 0.008)。我们还发现,当暴露于更清晰的刺激时,遭受过性虐待的组在恐惧识别方面没有表现出改善,尽管这种组间差异没有达到统计学意义(P = 0.064)。我们没有发现虐待组之间的其他差异,无论是在临床症状(PANSS因素)还是在暗示任务得分方面。结论不同童年创伤类型的精神障碍患者在恐惧识别方面存在差异。
{"title":"Efectos del trauma infantil en el reconocimiento de la expresión facial de miedo en psicosis","authors":"Antía Brañas ,&nbsp;Guillermo Lahera ,&nbsp;María Luisa Barrigón ,&nbsp;Manuel Canal-Rivero ,&nbsp;Miguel Ruiz-Veguilla","doi":"10.1016/j.rpsm.2019.01.005","DOIUrl":"10.1016/j.rpsm.2019.01.005","url":null,"abstract":"<div><h3>Introduction</h3><p>Childhood trauma has been reported as a risk factor for psychosis. Different types of traumatic experiences in childhood could lead to different clinical manifestations in psychotic disorders.</p></div><div><h3>Material and methods</h3><p>We studied differences in social cognition (emotion recognition and theory of mind) and clinical symptoms in a sample of 62 patients with psychosis (less than 5 years of illness) and childhood trauma, analysing performance by trauma type.</p></div><div><h3>Results</h3><p>Psychotic patients with a history of childhood trauma other than sexual abuse were more capable of recognizing fear as a facial emotion (especially when facial stimuli were non-degraded) than participants with a history of sexual abuse or with no history of childhood trauma (<em>P</em> <!-->=<!--> <!-->.008). We also found that the group that had suffered sexual abuse did not show improvement in fear recognition when exposed to clearer stimuli, although this intergroup difference did not reach statistical significance (<em>P</em> <!-->=<!--> <!-->.064). We have not found other differences between abuse groups, neither in clinical symptoms (PANSS factors) nor in Hinting Task scores.</p></div><div><h3>Conclusion</h3><p>We have found differences in fear recognition among patients with psychotic disorders who have experienced different types of childhood trauma.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"15 1","pages":"Pages 29-37"},"PeriodicalIF":9.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989119300229/pdfft?md5=572c81690f35521be63261a0dc5b25cf&pid=1-s2.0-S1888989119300229-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37231997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
[Suicidal attempt and suicidal ideation during the COVID-19 pandemic compared to previous years]. [COVID-19大流行期间的自杀企图和自杀意念与往年相比]。
IF 9.2 3区 医学 Q1 PSYCHIATRY Pub Date : 2021-11-19 DOI: 10.1016/j.rpsm.2021.11.004
Miguel A Jerónimo, Sergio Piñar, Pilar Samos, Ana M Gonzalez, Magda Bellsolà, Agnès Sabaté, Jordi León, Xavier Aliart, Luis M Martín, Rosa Aceña, Victor Pérez, David Córcoles

Introduction: Since the COVID-19 pandemic began, warnings have been made about the impact on the mental health of the population and as occurred in previous pandemics, an increase in suicide rates had been anticipated. To date, studies differ with regard to whether suicide rates are being affected during the COVID pandemic.

Material and methods: All individuals registered for suicidal ideation or suicidal attempt in the Suicide Risk Code (CRS) from the city of Barcelona from January 1, 2018 to June 30, 2021 have been included. A bivariate analysis has been carried out between the 2018-2019 period and the pandemic period. The percentage increase in the monthly incidence of CRS cases has been calculated, using the average monthly incidence for the 2018-2019 period as a reference.

Results: A total of 3388 consultations for suicide ideation or suicidal attempt were registered. There has been an increase of 43.20% in the monthly incidence of suicidal ideation and suicidal attempts during the pandemic compared to the 2018-2019 period, reaching a maximum increase of 573.8% in young people under 18 years in the month of May 2021.

Conclusions: During the COVID-19 pandemic period, consultations for suicidal ideation and suicidal attempts have increased compared to the previous 2 years in the city of Barcelona. It should be noted this growth especially in young people under 18 years.

导言:自 COVID-19 大流行开始以来,人们就一直在警告其对人们心理健康的影响,而且与以往的大流行一样,人们预计自杀率会上升。迄今为止,有关 COVID 大流行期间自杀率是否受到影响的研究各不相同:纳入了巴塞罗那市从 2018 年 1 月 1 日至 2021 年 6 月 30 日期间在自杀风险代码(CRS)中登记的所有有自杀倾向或自杀未遂的人。对 2018-2019 年期间和大流行期间进行了二元分析。以2018-2019年期间的月平均发病率为参考,计算了CRS病例月发病率的增长百分比:共登记了 3388 例因自杀意念或自杀未遂而就诊的病例。与 2018-2019 年期间相比,大流行期间自杀意念和自杀未遂的月发病率增加了 43.20%,2021 年 5 月,18 岁以下青少年的发病率增幅最大,达到 573.8%:在 COVID-19 大流行期间,巴塞罗那市因自杀意念和自杀企图而就诊的人数与前两年相比有所增加。值得注意的是,18 岁以下青少年的发病率增长尤为明显。
{"title":"[Suicidal attempt and suicidal ideation during the COVID-19 pandemic compared to previous years].","authors":"Miguel A Jerónimo, Sergio Piñar, Pilar Samos, Ana M Gonzalez, Magda Bellsolà, Agnès Sabaté, Jordi León, Xavier Aliart, Luis M Martín, Rosa Aceña, Victor Pérez, David Córcoles","doi":"10.1016/j.rpsm.2021.11.004","DOIUrl":"10.1016/j.rpsm.2021.11.004","url":null,"abstract":"<p><strong>Introduction: </strong>Since the COVID-19 pandemic began, warnings have been made about the impact on the mental health of the population and as occurred in previous pandemics, an increase in suicide rates had been anticipated. To date, studies differ with regard to whether suicide rates are being affected during the COVID pandemic.</p><p><strong>Material and methods: </strong>All individuals registered for suicidal ideation or suicidal attempt in the Suicide Risk Code (CRS) from the city of Barcelona from January 1, 2018 to June 30, 2021 have been included. A bivariate analysis has been carried out between the 2018-2019 period and the pandemic period. The percentage increase in the monthly incidence of CRS cases has been calculated, using the average monthly incidence for the 2018-2019 period as a reference.</p><p><strong>Results: </strong>A total of 3388 consultations for suicide ideation or suicidal attempt were registered. There has been an increase of 43.20% in the monthly incidence of suicidal ideation and suicidal attempts during the pandemic compared to the 2018-2019 period, reaching a maximum increase of 573.8% in young people under 18 years in the month of May 2021.</p><p><strong>Conclusions: </strong>During the COVID-19 pandemic period, consultations for suicidal ideation and suicidal attempts have increased compared to the previous 2 years in the city of Barcelona. It should be noted this growth especially in young people under 18 years.</p>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2021-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9589183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
La Convención de Naciones Unidas sobre los Derechos de las Personas con Discapacidad: los efectos del debate 《联合国残疾人权利公约:辩论的影响》
IF 9.2 3区 医学 Q1 PSYCHIATRY Pub Date : 2021-10-01 DOI: 10.1016/j.rpsm.2021.02.001
Julián Gómez Peñalver, Carmen Fernández de Henestrosa Serra, José Luis Ayuso-Mateos
{"title":"La Convención de Naciones Unidas sobre los Derechos de las Personas con Discapacidad: los efectos del debate","authors":"Julián Gómez Peñalver,&nbsp;Carmen Fernández de Henestrosa Serra,&nbsp;José Luis Ayuso-Mateos","doi":"10.1016/j.rpsm.2021.02.001","DOIUrl":"10.1016/j.rpsm.2021.02.001","url":null,"abstract":"","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"14 4","pages":"Pages 230-231"},"PeriodicalIF":9.2,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989121000276/pdfft?md5=1757b7377c6dcdb8e82eefd1215b814b&pid=1-s2.0-S1888989121000276-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25365641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Exploring the factor structure of the mini-ICF-APP in an inpatient clinical sample, according to the psychiatric diagnosis 根据精神病学诊断,探讨住院患者临床样本中mini-ICF-APP的因子结构
IF 9.2 3区 医学 Q1 PSYCHIATRY Pub Date : 2021-10-01 DOI: 10.1016/j.rpsm.2020.05.008
Stephan T. Egger , Godehard Weniger , Julio Bobes , Erich Seifritz , Stefan Vetter

Introduction

Psychosocial functioning is a key factor determining prognosis, severity, impairment and quality of life in people who have a mental disorder. The mini-ICF-APP was developed to provide a standardised classification of functioning and disability. However, despite its gaining popularity little is known about its structure and performance. This paper examines the structure of the mini-ICF-APP using factor analysis techniques.

Materials and methods

In a clinical sample of 3178 patients, with psychiatric diagnoses from several ICD-10 categories, we analysed internal consistency, item inter-correlations and the factorial structure of the data, with reference to ICD-10 diagnostic categories; Neurocognitive Disorders; Alcohol Use Disorders; Substance Use Disorders; Schizophrenia and Psychotic Disorders; Bipolar Disorder; Major Depressive Disorder; Anxiety Disorders; Personality Disorders; and Neurodevelopmental Disorders.

Results

We found good internal consistency and item inter-correlations (Cronbach alpha = 0.92) for the mini-ICF-APP. We were able to identify pivotal domains (flexibility, assertiveness and intimate relationships), which demonstrate sub-threshold influences on other domains. The factor analysis yielded a one-factor model as ideal for the whole sample and for all diagnostic categories. For some diagnostic categories the data suggested a two or three-factor model, however, with poorer fit indices.

Conclusions

The factor structure of the mini-ICF-APP appears to modify according to the main diagnosis. However, a one-factor model demonstrates better fit regardless of diagnostic category. Consequently, we consider the mini-ICF-APP to be a trans-diagnostic measurement instrument for the assessment and grading of psychosocial functioning. The use of the mini-ICF-APP sum score seems to best reflect the degree of impairment in an individual, even taking into account that affected domains may lead to sub-threshold effects on other domains.

心理社会功能是决定精神障碍患者预后、严重程度、损害和生活质量的关键因素。mini-ICF-APP的开发是为了提供功能和残疾的标准化分类。然而,尽管它越来越受欢迎,但人们对它的结构和性能知之甚少。本文利用因子分析技术考察了mini-ICF-APP的结构。参考ICD-10的诊断分类,我们分析了3178例临床样本的内部一致性、项目相互相关性和数据的析因结构;神经认知障碍;酒精使用障碍;物质使用障碍;精神分裂症和精神障碍;双相情感障碍;重度抑郁症;焦虑障碍;人格障碍;以及神经发育障碍。结果mini-ICF-APP具有良好的内部一致性和项目间相关性(Cronbach alpha = 0.92)。我们能够确定关键领域(灵活性、自信和亲密关系),这些领域对其他领域的影响低于阈值。因子分析产生了一个单因素模型作为理想的整个样本和所有诊断类别。然而,对于某些诊断类别,数据显示是两个或三个因素的模型,拟合指数较差。结论mini-ICF-APP的因子结构随着主要诊断的不同而发生改变。然而,无论诊断类别如何,单因素模型都具有更好的拟合性。因此,我们认为mini-ICF-APP是一种跨诊断的测量工具,用于评估和评定心理社会功能。即使考虑到受影响的域可能导致其他域的亚阈值效应,使用mini-ICF-APP总评分似乎也能最好地反映个体的损伤程度。
{"title":"Exploring the factor structure of the mini-ICF-APP in an inpatient clinical sample, according to the psychiatric diagnosis","authors":"Stephan T. Egger ,&nbsp;Godehard Weniger ,&nbsp;Julio Bobes ,&nbsp;Erich Seifritz ,&nbsp;Stefan Vetter","doi":"10.1016/j.rpsm.2020.05.008","DOIUrl":"10.1016/j.rpsm.2020.05.008","url":null,"abstract":"<div><h3>Introduction</h3><p>Psychosocial functioning is a key factor determining prognosis, severity, impairment and quality of life in people who have a mental disorder. The mini-ICF-APP was developed to provide a standardised classification of functioning and disability. However, despite its gaining popularity little is known about its structure and performance. This paper examines the structure of the mini-ICF-APP using factor analysis techniques.</p></div><div><h3>Materials and methods</h3><p>In a clinical sample of 3178 patients, with psychiatric diagnoses from several ICD-10 categories, we analysed internal consistency, item inter-correlations and the factorial structure of the data, with reference to ICD-10 diagnostic categories; Neurocognitive Disorders; Alcohol Use Disorders; Substance Use Disorders; Schizophrenia and Psychotic Disorders; Bipolar Disorder; Major Depressive Disorder; Anxiety Disorders; Personality Disorders; and Neurodevelopmental Disorders.</p></div><div><h3>Results</h3><p>We found good internal consistency and item inter-correlations (Cronbach alpha<!--> <!-->=<!--> <!-->0.92) for the mini-ICF-APP. We were able to identify pivotal domains (flexibility, assertiveness and intimate relationships), which demonstrate sub-threshold influences on other domains. The factor analysis yielded a one-factor model as ideal for the whole sample and for all diagnostic categories. For some diagnostic categories the data suggested a two or three-factor model, however, with poorer fit indices.</p></div><div><h3>Conclusions</h3><p>The factor structure of the mini-ICF-APP appears to modify according to the main diagnosis. However, a one-factor model demonstrates better fit regardless of diagnostic category. Consequently, we consider the mini-ICF-APP to be a trans-diagnostic measurement instrument for the assessment and grading of psychosocial functioning. The use of the mini-ICF-APP sum score seems to best reflect the degree of impairment in an individual, even taking into account that affected domains may lead to sub-threshold effects on other domains.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"14 4","pages":"Pages 186-195"},"PeriodicalIF":9.2,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989120300665/pdfft?md5=8b5ff36bfd2f96489e0da5d926b2ec13&pid=1-s2.0-S1888989120300665-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38200551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Obsessive–compulsive symptoms in anxiety and depressive disorders: Influence of recent and/or traumatic life events 焦虑和抑郁障碍中的强迫症状:近期和/或创伤性生活事件的影响
IF 9.2 3区 医学 Q1 PSYCHIATRY Pub Date : 2021-10-01 DOI: 10.1016/j.rpsm.2020.12.002
Arantxa Orozco , Narcís Cardoner , Cristina F. Aragón , Salvador Ruiz-Murugarren , María Vicens , Miguel Ángel Álvarez-Mon , Guillermo Lahera

Introduction

A high prevalence of obsessive–compulsive symptoms (OCSs) in anxiety-depressive disorders ranging from 30 to 67% has been described.

Objective

This study aims to assess the presence and persistence of OCSs in an outpatient sample of subjects with anxiety and depressive disorders, as well as its relationship with recent life events (RLEs) and/or traumatic experiences (TEs).

Method

We conducted a prospective, observational, analytical study of 200 subjects with DSM-5 diagnoses of anxiety and/or depression. Participants were included by consecutive sampling and were evaluated at baseline and after 6–12 months (mean 8.5 months) of follow-up. The severity of the symptoms was assessed through the Hamilton Anxiety Scale (HARS) and Hamilton Scale for the evaluation of depression (HRSD-17), and comorbidity was assessed through the International Neuropsychiatric Interview (MINI). The Revised Inventory of Obsessions and Compulsions (OCI-R), the Recent Vital Changes Questionnaire (CVSV), and the Diagnostic Scale for Post-Traumatic Stress (PDS) were also administered.

Results

54% of the sample presented OCSs, and 30.5% presented one or more TEs throughout life. At the baseline visit, the presence of OCSs was associated with the severity of depressive symptoms (p = 0.028), the presence of TEs (p < 0.01), symptoms of post-traumatic stress disorder (p < 0.01) and the number of RLEs (p < 0.01). Response rate at follow-up was 38%, and persistence of OCSs was found in 60.5% of patients, independent of depressive or anxious symptoms, but was associated with the number of RLEs (p < 0.01).

Conclusion

The presence of OCSs in patients with anxiety and depressive disorders is frequent and persistent. Anxious-depressive patients with a history of TEs and RLEs had higher OCS levels. These findings highlight the importance of early detection and the use of therapeutic strategies focused on resilience to stress and trauma.

据报道,焦虑抑郁障碍中强迫症(OCSs)的患病率很高,从30%到67%不等。目的本研究旨在评估门诊焦虑症和抑郁症患者OCSs的存在和持续性,以及其与近期生活事件(RLEs)和/或创伤经历(TEs)的关系。方法对200名DSM-5诊断为焦虑和/或抑郁的受试者进行前瞻性、观察性、分析性研究。参与者通过连续抽样纳入,并在基线和6-12个月(平均8.5个月)随访后进行评估。通过汉密尔顿焦虑量表(HARS)和汉密尔顿抑郁评估量表(HRSD-17)评估症状严重程度,通过国际神经精神病学访谈(MINI)评估合并症。同时进行强迫强迫修正量表(OCI-R)、近期生命变化问卷(CVSV)和创伤后应激诊断量表(PDS)。结果54%的患者出现过OCSs, 30.5%的患者一生中出现过一次或多次TEs。基线访视时,OCSs的存在与抑郁症状的严重程度相关(p = 0.028), TEs的存在与抑郁症状的严重程度相关(p <0.01),创伤后应激障碍症状(p <0.01)和RLEs数量(p <0.01)。随访有效率为38%,60.5%的患者持续存在OCSs,与抑郁或焦虑症状无关,但与RLEs次数有关(p <0.01)。结论焦虑抑郁障碍患者出现OCSs的频率和持续性较高。有TEs和RLEs病史的焦虑抑郁患者OCS水平较高。这些发现强调了早期发现和使用治疗策略的重要性,重点是对压力和创伤的恢复能力。
{"title":"Obsessive–compulsive symptoms in anxiety and depressive disorders: Influence of recent and/or traumatic life events","authors":"Arantxa Orozco ,&nbsp;Narcís Cardoner ,&nbsp;Cristina F. Aragón ,&nbsp;Salvador Ruiz-Murugarren ,&nbsp;María Vicens ,&nbsp;Miguel Ángel Álvarez-Mon ,&nbsp;Guillermo Lahera","doi":"10.1016/j.rpsm.2020.12.002","DOIUrl":"10.1016/j.rpsm.2020.12.002","url":null,"abstract":"<div><h3>Introduction</h3><p>A high prevalence of obsessive–compulsive symptoms (OCSs) in anxiety-depressive disorders ranging from 30 to 67% has been described.</p></div><div><h3>Objective</h3><p>This study aims to assess the presence and persistence of OCSs in an outpatient sample of subjects with anxiety and depressive disorders, as well as its relationship with recent life events (RLEs) and/or traumatic experiences (TEs).</p></div><div><h3>Method</h3><p>We conducted a prospective, observational, analytical study of 200 subjects with DSM-5 diagnoses of anxiety and/or depression. Participants were included by consecutive sampling and were evaluated at baseline and after 6–12 months (mean 8.5 months) of follow-up. The severity of the symptoms was assessed through the Hamilton Anxiety Scale (HARS) and Hamilton Scale for the evaluation of depression (HRSD-17), and comorbidity was assessed through the International Neuropsychiatric Interview (MINI). The Revised Inventory of Obsessions and Compulsions (OCI-R), the Recent Vital Changes Questionnaire (CVSV), and the Diagnostic Scale for Post-Traumatic Stress (PDS) were also administered.</p></div><div><h3>Results</h3><p>54% of the sample presented OCSs, and 30.5% presented one or more TEs throughout life. At the baseline visit, the presence of OCSs was associated with the severity of depressive symptoms (<em>p</em> <!-->=<!--> <!-->0.028), the presence of TEs (<em>p</em> <!-->&lt;<!--> <!-->0.01), symptoms of post-traumatic stress disorder (<em>p</em> <!-->&lt;<!--> <!-->0.01) and the number of RLEs (<em>p</em> <!-->&lt;<!--> <!-->0.01). Response rate at follow-up was 38%, and persistence of OCSs was found in 60.5% of patients, independent of depressive or anxious symptoms, but was associated with the number of RLEs (<em>p</em> <!-->&lt;<!--> <!-->0.01).</p></div><div><h3>Conclusion</h3><p>The presence of OCSs in patients with anxiety and depressive disorders is frequent and persistent. Anxious-depressive patients with a history of TEs and RLEs had higher OCS levels. These findings highlight the importance of early detection and the use of therapeutic strategies focused on resilience to stress and trauma.</p></div>","PeriodicalId":21391,"journal":{"name":"Revista de psiquiatria y salud mental","volume":"14 4","pages":"Pages 218-226"},"PeriodicalIF":9.2,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1888989120301294/pdfft?md5=8d2551f4d35f931ee739ef08de16ca08&pid=1-s2.0-S1888989120301294-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38747424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
期刊
Revista de psiquiatria y salud mental
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1