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Isolation, and characterization of Cladosporium alboflavescens for Acetaminophen biodegradation 用于对乙酰氨基酚进行生物降解的 Cladosporium alboflavescens 的分离和特征描述
Pub Date : 2023-12-31 DOI: 10.31357/vjs.v26i02.6804
M. Waghmode, Neha Patil
One of the pharmaceutical micropollutants with a detrimental effect on the environment is paracetamol. Mycoremediation of the pollutants is a widely accepted concept based on cost and eco-friendly nature. Fungi isolated from pharmaceutical industry effluent have been used to target the biodegradation of paracetamol. The fungus’s internal transcribed spacer (ITS 1) sequencing matched that of Cladosporium alboflavescens (GenBank accession number OQ977005) by 99.81%. The strain demonstrated 89% biodegradation of paracetamol (1000 ppm) after 96 hours of incubation with 4-aminophenol as the predominant biodegradative metabolite, according to the spectrophotometric and high-performance liquid chromatographic analysis. The half-life of 1.44 days and simple first order kinetics were proposed by the Computer Assisted Kinetic Evaluation (CAKE) tool used to examinethe biodegradation kinetics. Key words: Acetaminophen, 4-aminophenol, Cladosporium, Mycoremediation
扑热息痛是一种对环境有有害影响的药物微污染物。基于成本和生态友好的性质,对污染物进行菌核修复是一个广为接受的概念。从制药工业废水中分离出来的真菌被用于对扑热息痛的生物降解。该真菌的内部转录间隔(ITS 1)测序与 Cladosporium alboflavescens(GenBank 编号 OQ977005)的测序吻合 99.81%。根据分光光度法和高效液相色谱分析,该菌株在培养 96 小时后对扑热息痛(1000 ppm)的生物降解率为 89%,其中 4-氨基苯酚是主要的生物降解代谢物。利用计算机辅助动力学评估(CAKE)工具对生物降解动力学进行了研究,结果表明半衰期为 1.44 天,并采用了简单的一阶动力学。 关键字对乙酰氨基酚、4-氨基苯酚、Cladosporium、菌核修复
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引用次数: 0
Comparative Phyto and Physicochemical Parameters of the Therapeutic Plant Syzygium cumini (L.) Skeels in Jaffna District 贾夫纳县治疗植物 Syzygium cumini (L.) Skeels 的植物和理化参数比较
Pub Date : 2023-12-31 DOI: 10.31357/vjs.v26i02.6808
Gowri Rajkumar, Vinotha Sanmugarajah, Mihiri R. Jayasinghe
Syzygium cumini (L.) Skeels (Myrtaceae) is an evergreen tree, grown widely in Sri Lanka. It is regularly recognized as jambolan, black plum, and jamun. It is an extensively used therapeutic herbal in the treatment of innumerable illnesses, particularly in Diabetes mellitus in traditional medicine. The goal of the research was to compare the phytochemical and physicochemical properties between the different parts of jambolana tree which is naturally found in Sri Lanka. Proximate estimation of physicochemical properties of dried matured different parts as bark, leaves, fruits, and seeds of the Syzygium cumini havebeen done in the current study rendering to the standard protocols recommended by the World Health Organization (WHO) and Association of Analytical Chemist (AOAC). This study includes electrical conductivity value, moisture content, fat content, and different ash contents analysis. It was found that the leaves had the highest electrical conductivity (16.67±1.53) and the bark had the lowest electrical conductivity (2.44±0.03). The moisture content of the bark was lower (11.30±0.44) in comparison tothat of the seeds (16.34±0.43). Furthermore, the bark had the highest fat content (1.02±0.03) and acid insoluble ash (2.65±0.89), when compared to the seeds (0.65±0.01) and leaves (1.00±0.88) respectively. The seeds had the highest pH (5.39±0.08); total ash (2.18±0.06) and water-soluble ash (5.25±0.55), while the fruits had the highest sulphated ash (1.99±0.55). Qualitative inspection revealed that hot ethanolic seed extracts contained high levels of flavonoids, tannins, phenols, glycosides, alkaloids, terpenoids and quinones, in addition to other parts, which also had high levels of alkaloid content (81.06 mg/g). The current study will contribute useful data in the precise documentation and validation of various parts of S. cumini and may aid in removing contaminants in the preparation of nutraceuticals or medicine. Keywords: Medicinal Plant, Parts, Parameters, Physicochemical, Phytochemical, Syzygium cumini
Syzygium cumini (L.) Skeels(桃金娘科)是一种常绿乔木,在斯里兰卡广泛种植。它通常被称为 jambolan、black plum 和 jamun。在传统医学中,它被广泛用于治疗多种疾病,尤其是糖尿病。这项研究的目的是比较斯里兰卡天然存在的 jambolana 树不同部分的植物化学和物理化学特性。本研究按照世界卫生组织(WHO)和分析化学家协会(AOAC)推荐的标准方案,对干制成熟的茜草不同部位(树皮、叶子、果实和种子)的理化性质进行了近似估计。这项研究包括电导率值、水分含量、脂肪含量和不同灰分含量的分析。结果发现,树叶的导电率最高(16.67±1.53),树皮的导电率最低(2.44±0.03)。树皮的含水量(11.30±0.44)低于种子的含水量(16.34±0.43)。此外,与种子(0.65±0.01)和叶片(1.00±0.88)相比,树皮的脂肪含量(1.02±0.03)和酸不溶灰分(2.65±0.89)最高。种子的 pH 值(5.39±0.08)、总灰分(2.18±0.06)和水溶性灰分(5.25±0.55)最高,而果实的硫酸盐灰分(1.99±0.55)最高。定性检测显示,种子热乙醇提取物中含有大量黄酮类、单宁、酚类、苷类、生物碱、萜类和醌类化合物,此外,其他部分的生物碱含量也很高(81.06 mg/g)。目前的研究将为精确记录和验证 S. cumini 的各种部分提供有用的数据,并有助于在制备营养保健品或药品时去除污染物。 关键词药用植物 各部位 参数 物理化学 植物化学 茜草
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引用次数: 0
Determination of protein content in cooked foods consumed by toddlers aged 1-2 years in Sri Lanka 测定斯里兰卡 1-2 岁幼儿食用的熟食中的蛋白质含量
Pub Date : 2023-12-31 DOI: 10.31357/vjs.v26i02.6805
M. Thishani, Shanika Pathirathne, Wijelath Arachchige Gihan, Erandika Wijelath, W. A. D. Nayananjalie, Renuka Jayatissa, A. Buddhika, Gayani Silva
In early life, protein deficiency as well as heavy protein intake cause adverse conditions. Therefore, the present study aimed to assess the protein adequacy of diets in 1-2-year-old toddlers in the Alawwa Medical Officer of Health (MOH) area, Kurunegala, Sri Lanka. Data on food consumption was obtained by 24-hour dietary recall method from selected caregivers (n=60) andcommonly consumed foods (n=30) were cooked using household preparation protocols practiced in the area. They were homogenized and analyzed for protein. The majority of toddlers among the selected population consumed rice-based meals (73%) as the main meal (cooked rice with vegetable accompaniments), while 27% preferred mixed diets (a mixture of vegetables, pulses, leafy vegetables and fish along with rice). A serving of commercial cereal products provided the highest estimateddaily intake (EDI) of protein (10.70 ± 0.40 g). The average EDI of protein of all categories of foods per portion (rice, vegetables, pulses, green leaves, fish, eggs, rice mixtures and cereal products) was 31.55 ± 0.88 g, contributing to the recommended dietary allowance (RDA) of 242.64% and 150.17% for 1-2 year toddlers as defined by the Department of Agriculture, United States (USDA) and Sri Lankan RDA defined by Medical Research Institute (MRI), respectively. In conclusion, the cooked foods prepared according to local recipes fulfilled the dietary requirements of protein for toddlers aged 1-2 years in the Alawwa MOH area following USDA and Sri Lankan nutrition guidelines. Keywords: Estimated Daily Intake, Protein, Recommended Dietary Allowance, Toddlers
在生命早期,蛋白质缺乏和大量摄入蛋白质都会导致不良状况。因此,本研究旨在评估斯里兰卡库鲁内加拉(Kurunegala)Alawwa卫生局(MOH)地区1-2岁幼儿饮食中蛋白质的充足性。研究人员通过24小时膳食回忆法从选定的照料者(60人)处获得了食物消耗量数据,并采用该地区的家庭烹饪方法烹制了单次食用的食物(30人)。对这些食物进行均质化处理并分析蛋白质含量。在所选人群中,大多数幼儿(73%)以米饭为主食(煮熟的米饭配以蔬菜),27%的幼儿喜欢混合饮食(蔬菜、豆类、叶菜类和鱼类与米饭的混合物)。一份商业谷物产品提供了最高的蛋白质估计日摄入量(10.70 ± 0.40 克)。各类食物(米饭、蔬菜、豆类、绿叶、鱼、鸡蛋、米饭混合物和谷物制品)每份的平均蛋白质日摄入量为 31.55 ± 0.88 克,分别达到美国农业部(USDA)和斯里兰卡医学研究所(MRI)规定的 1-2 岁幼儿建议膳食摄入量(RDA)的 242.64% 和 150.17%。总之,根据美国农业部和斯里兰卡营养指南,按照当地食谱烹制的熟食符合阿拉瓦卫生部地区1-2岁幼儿对蛋白质的膳食要求。 关键词估计日摄入量 蛋白质 膳食建议摄入量 幼儿
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引用次数: 0
Hydrogen Economy: Are we ready? 氢经济:我们准备好了吗?
Pub Date : 2023-12-31 DOI: 10.31357/vjs.v26i02.6801
PhD Frsc K.M. Nalin de Silva
The planet has witnessed an extraordinary economic rebound after the pandemic during the last couple of years. However, the cost of energy started to increase dramatically, and the global energy markets affected due to the war between Ukraine and Russia. The markets were further shaken due to the present crisis in the Middle East after the escalation of hostilities between Israel and Palestine. The prices of various energy forms such as natural gas have reached record highs and countries like SriLanka were severely affected. The situation was aggravated in Sri Lanka due to economic mismanagement, corruption and inefficient administration resulting in an irreversible economic meltdown. The depletion of foreign reserves coupled with devaluation of the currency inhibited the buying power of material in the international market. Out of many commodities, energy was the critical factor due to its multimodal influence for sustainable growth of the country. The enormous cost of energy has contributed to high inflation resulting in increasing poverty levels of a majority of families in Sri Lanka. The damage incurred to industry was unimaginable as most of the small and medium size enterprises were forced to shut down while other companies had to curtail the output, resulting in reduced GDP. The country has therefore experienced the highest fuel and electricity prices during the last year mainly due to the dependence of a fossil fuel-based economy. The country witnessed long power cuts and power shortages during the last couple of years due to the dependence of oil or coal imports for power generation. The whole world is moving towards clean energy technologies due to the oil crisis in the world. In this context, renewable energy sources such as solar power, wind power, hydropower and tidal power play a major role in contributing towards sustainable power generation. In addition, the energy from renewable sources prevents air pollution. As a country are we exploring the true potential of these avenues or are we seriously considering exploration of new energy sources? It is predicted to experience a shortage of fossil fuels in the next few decades due to the depletion of finite petroleum reserves. Therefore, scientists have taken a tremendous step in diverting their attention to alternative sustainable fuel technologies. In this context hydrogen plays a major role in replacing fossil fuel sources in a range of applications. A hydrogen economy does not mean the total replacement of other energy sources. This term has a broader meaning, and the emphasis is given to the role that hydrogen can play alongside other environmentally harmful technologies to slowly phase out the dependency on fossil fuels. This will allow countries like Sri Lanka to detach from the total dependency of fossil fuels in the automobile industry. A hydrogen-based economy, however, requires the use of advanced technologies for economical and environmentally clean production, storage, and
在过去的几年里,地球见证了大流行病后非同寻常的经济反弹。然而,由于乌克兰和俄罗斯之间的战争,能源成本开始急剧上升,全球能源市场受到影响。以色列和巴勒斯坦敌对行动升级后,中东危机进一步动摇了市场。天然气等各种能源形式的价格创下历史新高,斯里兰卡等国受到严重影响。由于经济管理不善、腐败和行政效率低下,斯里兰卡的局势进一步恶化,造成了不可逆转的经济崩溃。外汇储备枯竭加上货币贬值,抑制了国际市场上的物质购买力。在众多商品中,能源因其对国家可持续增长的多模式影响而成为关键因素。巨大的能源成本导致了高通胀,从而加剧了斯里兰卡大多数家庭的贫困程度。大多数中小型企业被迫停产,其他公司不得不削减产量,导致国内生产总值下降,给工业造成的损失难以想象。因此,主要由于依赖化石燃料经济,去年斯里兰卡经历了最高的燃料和电力价格。由于依赖进口石油或煤炭发电,在过去几年里,该国经历了长时间的停电和电力短缺。由于世界石油危机,全世界都在转向清洁能源技术。在这种情况下,太阳能、风能、水能和潮汐能等可再生能源在促进可持续发电方面发挥了重要作用。此外,可再生能源还能防止空气污染。作为一个国家,我们是否正在发掘这些途径的真正潜力,或者我们是否正在认真考虑探索新能源?据预测,由于石油储量有限,未来几十年化石燃料将出现短缺。因此,科学家们已经迈出了巨大的一步,将注意力转移到可持续的替代燃料技术上。在此背景下,氢在一系列应用中替代化石燃料来源方面发挥着重要作用。 氢经济并不意味着完全取代其他能源。这个词的含义更广,它强调的是氢气可以与其他对环境有害的技术一起发挥作用,慢慢地逐步摆脱对化石燃料的依赖。这将使斯里兰卡等国的汽车工业摆脱对化石燃料的完全依赖。然而,以氢为基础的经济需要使用先进技术,以经济、环保的方式生产、储存和安全运输氢燃料。从化石燃料向氢燃料的转变在污染和能源安全方面具有重大优势。向氢经济的转变不会一蹴而就,这主要是由于在开发生产和储存氢的新材料和方法方面存在技术障碍。氢作为一种能源载体之所以具有吸引力,主要是因为其能量含量约为液态碳氢化合物的三倍。氢气可以在燃料电池中与氧气燃烧,释放能量并产生水,同时不会造成空气污染。这对于减少碳足迹和在拥挤不堪的大都市地区提供无污染的运输系统来说,是一个很有吸引力的特点。此外,氢可以从包括水在内的各种来源产生,从而减少对化石燃料的依赖。 据预测,氢气将在发电领域发挥重要作用,尤其是在汽车行业。使用氢作为燃料的优势非常显著,然而,燃料电池驱动汽车的生产却充满挑战。许多大型汽车公司已经开发出氢动力汽车,目前正在许多国家使用。日本和韩国在这方面走在了前列。丰田 Mirai 和现代 Nexo 就是在全球燃料电池汽车市场上占据主导地位的两个例子。最近,丰田推出了 GR Yaris H2,这是一款先进的氢动力汽车。与燃料电池技术不同的是,这项新技术的主要区别在于,这种汽车在传统的内燃机中使用氢作为可燃燃料。然而,由于技术障碍,氢动力汽车与电动汽车相比较为罕见。其中一个原因是,由于缺乏基础设施,普通汽车驾驶员无法方便、安全地获取氢气。此外,车内氢气储存也存在问题。
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引用次数: 0
High-frequency Noise Removal of Audio Files using Daubechies Wavelet Transform 利用道布奇斯小波变换去除音频文件中的高频噪声
Pub Date : 2023-12-31 DOI: 10.31357/vjs.v26i02.6807
N. K. Kularathne, M. M. P. M. Fernando, J. M. U. T. D. Jayasinghe
In general, audio signals are contaminated with various types of noise. This paper presents a novel signal processing method developed for high-frequency noise elimination using wavelet transforms. As a continuation of a previous study that used Fourier transform for noise removal in audio files, in this study Daubechies wavelets were used to reduce computational complexity and achieve better noise reduction performances. Compared to the Fourier transform, the Daubechies wavelet transform method removes the noise in each signal while preserving its vital characteristics. The suitable level of the Daubechies wavelet for noise removal in each channel was obtained using a trial-and-error approach. It was identified that the ideal range for the level of the Daubechies wavelets for noise removal is between 17 and 20. Moreover, unlike the Fourier transform, the Daubechies wavelet transform demonstrates a proficient capacity in eliminating noise from data point that lies completely outside the rest in the audio data set. Wolfram Mathematica 12.3 software package was used to complete this research. This method can be applied toconserve vintage audio recordings originally recorded in cassettes and spools. Keywords: Digital Signal Processing, Wavelet Transforms, Daubechies Wavelet Transform, Fourier Transforms, Noise Removal
一般来说,音频信号会受到各种噪声的污染。本文介绍了一种利用小波变换消除高频噪声的新型信号处理方法。作为之前使用傅立叶变换消除音频文件中噪声研究的延续,本研究使用了道贝歇小波,以降低计算复杂度并实现更好的降噪性能。与傅立叶变换相比,道贝歇小波变换方法在去除每个信号中的噪声的同时,还保留了其重要特征。通过试错法获得了适合去除各信道噪声的道别奇斯小波电平。结果表明,用于去除噪声的 Daubechies 小波电平的理想范围在 17 到 20 之间。此外,与傅立叶变换不同,道贝歇斯小波变换在消除音频数据集中完全不属于其他数据点的噪声方面表现出了卓越的能力。本研究使用了 Wolfram Mathematica 12.3 软件包。这种方法可用于保存最初录制在磁带和线轴中的老式音频录音。 关键词数字信号处理、小波变换、道别奇斯小波变换、傅里叶变换、噪声去除
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引用次数: 0
RFiD Threads® Technology for Circular Economy and Future Sustainability 促进循环经济和未来可持续发展的 RFiD Threads® 技术
Pub Date : 2023-12-31 DOI: 10.31357/vjs.v26i02.6802
Anura Rathnayake
Problem The fashion industry is the second most polluting industry globally [UNEP2021] - 85% of all textiles go to landfill each year [WEF2021]. There is growing demand for a shift to circular business models, with new concepts emerging such as “extended producer responsibility” [DEFRA2022], and policy announcements such as the EU Strategy for Sustainable and Circular Textiles, mandating Digital Product Passports (DPP) [EC2023].The Ellen McArthur Foundation [EMF2021] has stated that “Sustainability concerns among customers are also projected to heighten”. This fact, coupled with the preparation of potential new regulatory instruments such as ‘Extended Producer Responsibility’ and other critical regulatory developments, is pushing the industry to consider different and more sustainable ways of producing textile products. A new technology-infrastructure to facilitate this transition is required, to support companiesand consumers access critical data on individual garments. 150 billion items of clothing are produced annually worldwide [EMF2022], of which around 12.5 billion were tagged in 2022, using radiofrequency identification (RFID) technology [Checkpoint2022]. The use of RFID tags is increasing rapidly, with the market projected to reach $35.6 Billion by 2030 [MarketsAndMarkets2022]. However, there are mainly two sustainability related problems holding back the full potential of RFID in the fashion industry: Weaknesses in current RFID-tag technologies: low robustness, non-washability, and attachment to temporary labels not integrated with the garment itself. 12.5 Billion RFID-tags were used last year in the fashion industry, mainly for inventory management [Checkpoint2022]. Those billions of paper/metal/label tags are usually removed immediately after sale and end up in landfill (which is very bad for the environment), because they are not washable or comfortable to wear with thegarment. For garments to be traceable throughout their lifecycle (enabling efficiencies and circular models), there is a need for integrating permanent 'Digital Passports' (e.g. RFID) in each textile-based product, and for easy access to data contained in these Digital Passports. Lack of data access, exchange and integration between supply chain actors: Currently, stakeholders use their own independent data management system/s. Therefore, the biggest challenges for efficient recycling/reuse of clothing is lack of access to data on fibre/material content. This makes it very difficult to implement automated systems for breaking up and separating used clothing items into their different fibre components.
问题 时尚产业是全球第二大污染产业[UNEP2021] - 每年有 85% 的纺织品被填埋[WEF2021]。随着 "生产者延伸责任"[DEFRA2022]等新概念的出现,以及欧盟可持续和循环纺织品战略等政策声明的发布,向循环型商业模式转变的需求日益增长。这一事实,再加上潜在的新监管工具(如 "生产者延伸责任")的准备工作和其他重要的监管发展,正在推动该行业考虑以不同的、更具可持续性的方式生产纺织品。为促进这一转变,需要一种新的技术基础设施,以支持公司和消费者获取单件服装的关键数据。 全球每年生产 1500 亿件服装[EMF2022],其中约 125 亿件在 2022 年使用射频识别(RFID)技术贴上了标签[Checkpoint2022]。RFID 标签的使用正在迅速增加,预计到 2030 年市场规模将达到 356 亿美元[MarketsAndMarkets2022]。 然而,主要有两个与可持续发展相关的问题阻碍了 RFID 在时尚产业中充分发挥潜力: 当前 RFID 标签技术的弱点:坚固性低、不可洗涤、附着于临时标签而非与服装本身结合。去年,时装业使用了 125 亿个 RFID 标签,主要用于库存管理[Checkpoint2022]。这些数以亿计的纸质/金属/标签通常在销售后立即被移除,最终被填埋(这对环境非常不利),因为它们不能洗涤,也不能与服装一起穿着。为了实现服装整个生命周期的可追溯性(提高效率和循环模式),有必要在每件纺织品中集成永久性的 "数字护照"(如 RFID),并方便访问这些数字护照中的数据。 供应链参与者之间缺乏数据访问、交换和整合:目前,各利益相关方使用各自独立的数据管理系统。因此,服装高效回收/再利用面临的最大挑战是无法获取纤维/材料含量数据。这就很难实施自动系统,将旧衣物拆解成不同的纤维成分。
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引用次数: 0
Real-Time Subtitle Generator for Sinhala Speech 僧伽罗语实时字幕生成器
Pub Date : 2023-12-31 DOI: 10.31357/vjs.v26i02.6806
R.V.P.S. Akesh, R.G.N. Meegama
In today’s digital era, the significance of speech recognition technology cannot be overstated as it plays a pivotal role in enabling human-computer interaction and supporting various applications. This paper focuses on the development of a real-time subtitle generator for Sinhala speech using speech recognition techniques. The CMUSphinx toolkit, an open-source toolkit based on the Hidden Markov Model (HMM), is employed for the implementation of the application. Mel-frequency cepstral coefficients (MFCC) are utilized for feature extraction from the given ’wav’ format recordings. The paper places significant emphasis on the importance of a real-time subtitle generator for Sinhala speech and explores the existing literature in the field. It outlines the objectives of the research and discusses the achieved outcomes. By fine-tuning hyperparameters to enhance the recognition accuracy of the system, impressive results of 88.28% training accuracy and 11.72% Word Error Rate (WER) are attained. Thesignificance of this research is underscored by its methodological advancements, robust performance metrics, and the potential impact on facilitating seamless interactions and applications in the Sinhala speech domain. Keywords: Speech recognition, Real-time, Subtitle, CMUSphinx, Open source, Hidden Markov Model, Mel-frequency cepstral coefficients, ’wav’, Accuracy, Word Error Rate
在当今的数字时代,语音识别技术在实现人机交互和支持各种应用方面发挥着举足轻重的作用,其重要性怎么强调都不为过。本文的重点是利用语音识别技术开发僧伽罗语实时字幕生成器。CMUSphinx 工具包是一个基于隐马尔可夫模型(HMM)的开源工具包,它被用于实现该应用程序。在从给定的 "wav "格式录音中提取特征时,使用了梅尔频率共振频率系数(MFCC)。本文着重强调了僧伽罗语实时字幕生成器的重要性,并探讨了该领域的现有文献。论文概述了研究目标,并讨论了取得的成果。通过微调超参数来提高系统的识别准确率,取得了 88.28% 的训练准确率和 11.72% 的词错误率 (WER) 的骄人成绩。这项研究的意义在于其方法的先进性、强大的性能指标以及对促进僧伽罗语语音领域无缝交互和应用的潜在影响。 关键词语音识别、实时、字幕、CMUSphinx、开源、隐马尔可夫模型、Mel-frequency cepstral coefficients、"wav"、准确率、词错误率
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引用次数: 0
A Multi-Party Conversation-Based Effective Robotic Navigation System for Futuristic Vehicle 基于多方对话的未来车辆有效机器人导航系统
Pub Date : 2023-12-31 DOI: 10.31357/vjs.v26i02.6803
Yasith R Wanigarathna, D.N.M. Hettiarachchi, U. Manawadu, Ravindra De Silva
In response to the growing need for advanced in-car navigation systems that prioritize user experience and aim to reduce driver cognitive workload, this study addresses the research question of how to enhance the interaction between drivers and navigation systems. The focus is on minimizing distraction while providing personalized and geographically relevant information. The research introduces an innovative in-car robotic navigation system comprising three subsystem models: geofencing,personalization, and conversation. The dynamic geofencing model acquires geographic details related to the user's current location and provides information about required destinations. The personalization model tailors suggestions based on user preferences, while the conversation model, employing two virtual robots, fosters interactive multiparty conversations aligned with the driver's interests. The study's scope is specifically confined to interactive conversations centered on nearby restaurants and the driver's dietary preferences. Evaluation of the system indicates a notable prevalence of neutral expressions amongparticipants during interaction, suggesting that the implemented system successfully mitigates cognitive workload. Participants in the experiments express higher usability and interactivity levels, as evidenced by feedback collected at the study's conclusion, affirming the system's effectiveness in enhancing the user experience while maintaining a driver-friendly environment. Keywords: Human-Robot Interaction, Multiparty Conversation, In-Car Navigation
为了满足对优先考虑用户体验并旨在减少驾驶员认知工作量的先进车载导航系统日益增长的需求,本研究探讨了如何增强驾驶员与导航系统之间互动的研究问题。重点是在提供个性化和地理相关信息的同时,尽量减少分心。研究介绍了一种创新的车载机器人导航系统,包括三个子系统模型:地理围栏、个性化和对话。动态地理围栏模型获取与用户当前位置相关的地理详情,并提供所需目的地的信息。个性化模型根据用户的偏好为其量身定制建议,而对话模型则采用两个虚拟机器人,根据驾驶员的兴趣促进多方互动对话。研究范围特别局限于以附近餐馆和驾驶员饮食偏好为中心的互动对话。对该系统的评估表明,在互动过程中,参与者的中性表情非常普遍,这表明所实施的系统成功减轻了认知工作量。从研究结束时收集到的反馈意见来看,实验参与者表示系统的可用性和交互性水平较高,这肯定了该系统在提升用户体验的同时保持驾驶员友好环境的有效性。 关键词人机交互、多方对话、车载导航
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引用次数: 0
Indole-based Fluorometric and Colorimetric Chemosensors for the Selective Detection of Cu2+: A Brief Review From the Year 2011-2021 用于选择性检测 Cu2+ 的吲哚基荧光和比色化学传感器:2011-2021 年简要回顾
Pub Date : 2023-11-29 DOI: 10.31357/vjs.v1is1.6714
A.U.T. De Silva, K.G.U.R. Kumarasinghe
The development of chemosensors has been driven by concurrently advanced research in fluorescence and colorimetric chemosensing. Over the last few decades, the development of copper ion-selective fluorogenic and chromogenic chemosensors has been extensively studied due to their high sensitivity, low cost, and simplicity. They can interact with the metal ion in a unique manner and create measurable color, fluorescence, or redox potential changes. Copper (Cu2+) ion is deemed the third most prevalent transition metal in human beings owing to its various biological and physiological processes. It has drawn a great deal of attention from many researchers in various disciplines such as biology, medicine, and environmental studies. However, an excessive buildup of copper in the body has been linked to several diseases. Thus, more recent research is being focused on developing fluorometric and colorimetric chemosensors for the selective detection of copper ions. Recently, there have been a lot of studies reported in this field of study that describe highly sensitive and sophisticated indole-based chemosensors for various metal ions of interest. In addition, indole derivatives possess inherent fluorescence properties due to their electron-rich nature caused by the π-excessive system of indole, and therefore they can be employed in chemosensors for metal ion detection. Both cations and anions employ it as a molecular recognition system. This review summarizes selective and sensitive Cu2+ ion detection accomplished byvarious indole-based chemosensors between the years 2011 to 2021. Furthermore, sensor design, sensing methods, ligand-metal binding stoichiometry, association constant, and the detection limit by the chemosensors are all summarized and explored. Keywords: Indole, Fluorescent chemosensors, Colorimetric chemosensors, Cu2+, Turn-on, Turn-off
荧光和比色化学传感研究的同步发展推动了化学传感器的发展。在过去的几十年中,铜离子选择性荧光和显色化学传感器因其灵敏度高、成本低、操作简单而被广泛研究。它们能以独特的方式与金属离子相互作用,并产生可测量的颜色、荧光或氧化还原电位变化。铜(Cu2+)离子因其各种生物和生理过程而被认为是人类第三大过渡金属。它引起了生物学、医学和环境研究等各学科研究人员的极大关注。然而,铜在人体内的过度积聚与多种疾病有关。因此,近期的研究重点是开发用于选择性检测铜离子的荧光和比色化学传感器。最近,这一研究领域的许多研究报告都介绍了针对各种相关金属离子的高灵敏度和复杂的吲哚基化学传感器。此外,吲哚衍生物因其π-外向系统所产生的富电子性而具有固有的荧光特性,因此可用于金属离子检测的化学传感器中。阳离子和阴离子都将其作为分子识别系统。本综述总结了 2011 年至 2021 年间各种基于吲哚的化学传感器所实现的选择性和灵敏的 Cu2+ 离子检测。此外,还对传感器的设计、传感方法、配体与金属的结合比例、结合常数以及化学传感器的检测限进行了总结和探讨。 关键词:吲哚 荧光化学传感器吲哚 荧光化学传感器 比色化学传感器 Cu2+ 开启 关断
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引用次数: 0
Recent Advances in Green Approaches for Synthesis of Oxindole Derivatives 吲哚衍生物绿色合成方法的最新进展
Pub Date : 2023-11-29 DOI: 10.31357/vjs.v1is1.6715
D.M.T.A.Samaradiwakara, H.H.Kandambi, K.G.U.R. Kumarasinghe
Oxindole derivatives are nitrogen-containing, five-membered heterocyclic molecules found in both natural and synthetic substances with diverse biological functions. Owing to their pharmaceutical and therapeutic characteristics, oxindoles have received remarkable attention, and various oxindole-containing substances can be synthesized using many different approaches. With the discovery of the importance of oxindole derivatives in medicinal chemistry, mainly in drug synthesis, the demand for finding sustainable protocols has increased, as most classical methods have their limitations and flaws. Hence, it is crucial to establish efficient and sustainable techniques that are safe, cost-effective, have low energy consumption, and cause minimal environmental impact. Nowadays, the use of green solvents in organic synthesis has received much attention because they prevent the formation of waste, are environmentally friendly, and have easy work-up procedures. Green solvents such as water, deep eutectic solvents, ionic liquids, and polyethylene glycol can substitute hazardous solvents. Microwave irradiation, visible-light irradiation, electrochemical methods, and multi-component synthesis are all described under green approaches. Most of these approaches allow the reaction to proceed rapidly while releasing minimal waste into the environment. Recent discoveries in green chemistry applications can be considered a turning point in organic synthesis. This review focuses on promising green approaches, used for the synthesis of oxindole derivatives, carried out in recent years with typical examples in two sections: green solvents and green techniques. Keywords- Oxindole derivatives, Green solvents, Green techniques, Sustainable chemistry, Solvent-free.
吲哚衍生物是一种含氮的五元杂环分子,存在于天然物质和合成物质中,具有多种生物功能。由于其药物和治疗特性,吲哚类化合物备受关注,人们可以通过多种不同的方法合成各种含吲哚的物质。随着人们发现吲哚衍生物在药物化学(主要是药物合成)中的重要性,对寻找可持续方案的需求也随之增加,因为大多数经典方法都有其局限性和缺陷。因此,建立安全、经济、低能耗、对环境影响最小的高效可持续技术至关重要。如今,在有机合成中使用绿色溶剂已受到广泛关注,因为绿色溶剂可防止废物的形成,对环境友好,而且操作步骤简单。水、深共晶溶剂、离子液体和聚乙二醇等绿色溶剂可以替代有害溶剂。微波辐照、可见光辐照、电化学方法和多组分合成都属于绿色方法。大多数这些方法都能使反应快速进行,同时向环境排放最少的废物。最近在绿色化学应用方面的发现可以说是有机合成的一个转折点。本综述重点介绍了近年来用于合成吲哚衍生物的前景看好的绿色方法,并列举了绿色溶剂和绿色技术两部分的典型实例。 关键词:吲哚衍生物 绿色溶剂 绿色技术 可持续化学 无溶剂
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引用次数: 0
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Vidyodaya Journal of Science
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