Pub Date : 2022-07-01DOI: 10.31357/vjs.v25i01.5920
Gaveshana A. Sepalage, T. A. Nirmal Peiris
Solar energy is plentiful. Over the last decades, a significant portion of the energy market has been acquired by solar power. There are several types of solar cells in the market chosen, dependent on the application (Nayak et al., 2019). Silicon solar panels are commonly found in solar farms, and for domestic use, or in other words, it is the market leader. However, due to the specific processing of the silicon materials and lack of practical applicability due to its rigid and opaque nature, the worldwide deployment of silicon technology is still not at an appreciable level, especially in developing countries. Based on this, alternative approaches have been widely studied, out of which the most relevant technologies to mention here are Dye Sensitized Solar Cells (DSSCs) (Kokkonen et al., 2021) and Organic Photovoltaics (OPV) (Inganäs, 2018). DSSCs and OPV are based on materials that are easily processed compared to silicon and have attractive characteristics such as color variability and transparency, so they can be applied to windows and can be integrated into building aesthetic designs. With the continuous developments in these technologies, scientists were refining them to beat the efficiency and the stability achieved by its rival silicon solar cells.
{"title":"Rise of a Giant: Perovskite Solar Cells and Its Economic Viability","authors":"Gaveshana A. Sepalage, T. A. Nirmal Peiris","doi":"10.31357/vjs.v25i01.5920","DOIUrl":"https://doi.org/10.31357/vjs.v25i01.5920","url":null,"abstract":"Solar energy is plentiful. Over the last decades, a significant portion of the energy market has been acquired by solar power. There are several types of solar cells in the market chosen, dependent on the application (Nayak et al., 2019). Silicon solar panels are commonly found in solar farms, and for domestic use, or in other words, it is the market leader. However, due to the specific processing of the silicon materials and lack of practical applicability due to its rigid and opaque nature, the worldwide deployment of silicon technology is still not at an appreciable level, especially in developing countries. Based on this, alternative approaches have been widely studied, out of which the most relevant technologies to mention here are Dye Sensitized Solar Cells (DSSCs) (Kokkonen et al., 2021) and Organic Photovoltaics (OPV) (Inganäs, 2018). DSSCs and OPV are based on materials that are easily processed compared to silicon and have attractive characteristics such as color variability and transparency, so they can be applied to windows and can be integrated into building aesthetic designs. With the continuous developments in these technologies, scientists were refining them to beat the efficiency and the stability achieved by its rival silicon solar cells.","PeriodicalId":214405,"journal":{"name":"Vidyodaya Journal of Science","volume":"424 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126718731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Currently, there is an increased demand for advanced food packages, which can significantly increase the shelf life of food items. In the current context, it is envisaged that nanotechnology has the potential to address stability, toxicity, shelf-life, and low-cost issues of antimicrobials associated with the packaging industry. Antimicrobial nanocomposite systems are believed to be more efficient than their microscale counterparts due to the high surface area to volume ratio and quantum mechanical involvement in deciding their properties. As a result of high surface area, they are able to attach more copies of microbial molecules and cells, thus reducing the quantity of material required while significantly improving their activity. This study focuses on the development of slow-release antimicrobial material based on natural citrate (α-hydroxycitrate) intercalated layered double hydroxide (LDH) nanohybrid. Natural citrate ions available in Citrus aurantifolia (lime) were extracted by a simple chemical method and intercalated into Mg-Al-Layered Double Hydroxide following a one-step co-precipitation method. Successful intercalation of the citrate ion was confirmed by powder X-ray diffraction (PXRD) and Fourier transform infrared (FTIR) spectroscopic analysis. Release kinetics of resulted nanohybrid was studied and compared using different release kinetic models. Antimicrobial properties of this novel nanohybrid were confirmed against two common food pathogens, Colletotrichum gloeosporioides and Saccharomyces cerevisiae, and the results were compared against sodium benzoate, which is the commonly used commercial antimicrobial agent in the food industry. Successful intercalation of natural citrate ions into LDH and its activity against the tested microbes show the potential of using it as a slow-release nanohybrid material in many food-related applications. Keywords: Layered Double Hydroxide, α-Hydroxycitrate, Natural, Safe, Lime Extract, Slow Release, Antimicrobial
{"title":"Anti-microbial Nanohybrids Based on Naturally Derived Citric Acid Intercalated Layered Double Hydroxides","authors":"Shashikala Kuruppu, Upendra Rathnayake, Madhavi de Silva, Thilini Rupasinghe, Chanaka Sandaruwan","doi":"10.31357/vjs.v25i01.5929","DOIUrl":"https://doi.org/10.31357/vjs.v25i01.5929","url":null,"abstract":"Currently, there is an increased demand for advanced food packages, which can significantly increase the shelf life of food items. In the current context, it is envisaged that nanotechnology has the potential to address stability, toxicity, shelf-life, and low-cost issues of antimicrobials associated with the packaging industry. Antimicrobial nanocomposite systems are believed to be more efficient than their microscale counterparts due to the high surface area to volume ratio and quantum mechanical involvement in deciding their properties. As a result of high surface area, they are able to attach more copies of microbial molecules and cells, thus reducing the quantity of material required while significantly improving their activity. This study focuses on the development of slow-release antimicrobial material based on natural citrate (α-hydroxycitrate) intercalated layered double hydroxide (LDH) nanohybrid. Natural citrate ions available in Citrus aurantifolia (lime) were extracted by a simple chemical method and intercalated into Mg-Al-Layered Double Hydroxide following a one-step co-precipitation method. Successful intercalation of the citrate ion was confirmed by powder X-ray diffraction (PXRD) and Fourier transform infrared (FTIR) spectroscopic analysis. Release kinetics of resulted nanohybrid was studied and compared using different release kinetic models. Antimicrobial properties of this novel nanohybrid were confirmed against two common food pathogens, Colletotrichum gloeosporioides and Saccharomyces cerevisiae, and the results were compared against sodium benzoate, which is the commonly used commercial antimicrobial agent in the food industry. Successful intercalation of natural citrate ions into LDH and its activity against the tested microbes show the potential of using it as a slow-release nanohybrid material in many food-related applications. \u0000 \u0000Keywords: Layered Double Hydroxide, α-Hydroxycitrate, Natural, Safe, Lime Extract, Slow Release, Antimicrobial","PeriodicalId":214405,"journal":{"name":"Vidyodaya Journal of Science","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131782053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Globally there is severe water scarcity, and methods to reuse wastewater need to be adapted. The objective of this research was to determine the microbiological parameters of different wastewaters in order to study the potential of wastewater as a media to cultivate algae.Food, agriculture, drainage and municipal wastewater sample were collected in sterile bottles separately. Aerobic, anaerobic plate counts, yeast and mold counts were evaluated. Enumeration of coliform, fecal coliform, coliphages and microalgae was performed with all wastewater samples. Chlorella sp. and Spirogyra sp. were isolated from three different paddy field water samples, and growth studies were carried out in different wastewater media with standard sterile Chu’s medium and in sterile tap water medium as control.Heterotrophic, anaerobic bacteria, microalgae, yeast and molds were found in all types of wastewater. Agriculture wastewater had the highest value for aerobic, anaerobic, yeast and mold count in the highest dilution. Coliforms and fecal coliforms were absent in food and agriculture wastewaters on Eosin Methylene Blue (EMB) medium. Coliform and Fecal coliforms were only observed in drainage and municipal wastewater on Endo agar (EA) medium. Coliphages were absent only in agricultural wastewater and found in the highest numbers in municipal wastewater. Except for agricultural wastewater, other three types of wastewaters contain microbial contaminations. Agriculture wastewater medium significantly enhanced the growth of Chlorella sp. than the standard Chu’s medium. The growth of Spirogyra sp. was stimulated by the food wastewater medium than the other media. Keywords: Wastewaters, Microbiological parameter, Chlorella sp., Spirogyra sp., Coliforms
{"title":"Microbiological Parameters of Different Waste Waters to Evaluate Their Potential to be Use as a Media for Chlorella sp. and Spirogyra sp. Cultivation","authors":"Donbosco Lancy, Arulanantham Christie Thavaranjit, Gowri Rajkumar","doi":"10.31357/vjs.v25i01.5926","DOIUrl":"https://doi.org/10.31357/vjs.v25i01.5926","url":null,"abstract":"Globally there is severe water scarcity, and methods to reuse wastewater need to be adapted. The objective of this research was to determine the microbiological parameters of different wastewaters in order to study the potential of wastewater as a media to cultivate algae.Food, agriculture, drainage and municipal wastewater sample were collected in sterile bottles separately. Aerobic, anaerobic plate counts, yeast and mold counts were evaluated. Enumeration of coliform, fecal coliform, coliphages and microalgae was performed with all wastewater samples. Chlorella sp. and Spirogyra sp. were isolated from three different paddy field water samples, and growth studies were carried out in different wastewater media with standard sterile Chu’s medium and in sterile tap water medium as control.Heterotrophic, anaerobic bacteria, microalgae, yeast and molds were found in all types of wastewater. Agriculture wastewater had the highest value for aerobic, anaerobic, yeast and mold count in the highest dilution. Coliforms and fecal coliforms were absent in food and agriculture wastewaters on Eosin Methylene Blue (EMB) medium. Coliform and Fecal coliforms were only observed in drainage and municipal wastewater on Endo agar (EA) medium. Coliphages were absent only in agricultural wastewater and found in the highest numbers in municipal wastewater. Except for agricultural wastewater, other three types of wastewaters contain microbial contaminations. Agriculture wastewater medium significantly enhanced the growth of Chlorella sp. than the standard Chu’s medium. The growth of Spirogyra sp. was stimulated by the food wastewater medium than the other media. \u0000Keywords: Wastewaters, Microbiological parameter, Chlorella sp., Spirogyra sp., Coliforms","PeriodicalId":214405,"journal":{"name":"Vidyodaya Journal of Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133331865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.31357/vjs.v25i01.5923
Shyamal Mondal
Various substituted Dispiro [pyrrolo-piperazino-oxindole] have been synthesized by utilizing a simple and efficient two-step synthetic protocol by Grubbs metathesis in dichloromethane at 40°C. The structures and relative stereochemistry of the cycloadduct were confirmed by single-crystal X-ray diffraction, 1H and 13C NMR spectroscopy, and mass spectrometry. Keywords: Hexahydro-diazecane-dione, Metathesis, Cycloaddition, Grubbs Catalyst.
{"title":"A Simple and Efficient Two-step Synthesis of Hexahydro-diazecane-dione Derivatives","authors":"Shyamal Mondal","doi":"10.31357/vjs.v25i01.5923","DOIUrl":"https://doi.org/10.31357/vjs.v25i01.5923","url":null,"abstract":"Various substituted Dispiro [pyrrolo-piperazino-oxindole] have been synthesized by utilizing a simple and efficient two-step synthetic protocol by Grubbs metathesis in dichloromethane at 40°C. The structures and relative stereochemistry of the cycloadduct were confirmed by single-crystal X-ray diffraction, 1H and 13C NMR spectroscopy, and mass spectrometry. \u0000 \u0000Keywords: Hexahydro-diazecane-dione, Metathesis, Cycloaddition, Grubbs Catalyst.","PeriodicalId":214405,"journal":{"name":"Vidyodaya Journal of Science","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128663368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The unsustainability of the production of catalysts due to limited resources and higher energy demands makes it critical to explore and reengineer new catalytic materials for future applications. Woefully, the unrelenting demand for the metals/metal oxides increases both the financial and environmental cost, particularly in mining and synthesis, rendering consumption unsustainable in its current form. In this context, electrospinning offers a new template for designing sustainable ways of minimizing the higher loading of catalysts and recyclability. In this context, metals/metal oxide doped electrospun membranes have grasped a great scientific interest as sustainable catalysts due to their enhanced catalytic activity and synergistic structure-property relationship of the doped material and the matrix. More specifically, the selectivity arising from the electronic properties and quantum mechanical interactions at the nanoscale of metal/metal oxide nanoparticles coupled with interactions at the electrospun membrane interfaces lead to such enhanced properties. This review article summarizes the applications of metals/metal doped electrospun membranes in different aspects of catalysis, such as thermocatalysis, photocatalysis, organocatalysis and electrocatalysis, with a particular focus on their sustainability. Keywords: Sustainable catalysis, metal/metal oxide doped catalysts, electrospinning, organocatalysis, photocatalysis
{"title":"Application of Metal/Metal Oxide Doped Electrospun Nanofiber Membranes in Sustainable Catalysis","authors":"Senuri Kumarage, Chamalki Madhusha, Imalka Munaweera, Nilwala Kottegoda","doi":"10.31357/vjs.v25i01.5922","DOIUrl":"https://doi.org/10.31357/vjs.v25i01.5922","url":null,"abstract":"The unsustainability of the production of catalysts due to limited resources and higher energy demands makes it critical to explore and reengineer new catalytic materials for future applications. Woefully, the unrelenting demand for the metals/metal oxides increases both the financial and environmental cost, particularly in mining and synthesis, rendering consumption unsustainable in its current form. In this context, electrospinning offers a new template for designing sustainable ways of minimizing the higher loading of catalysts and recyclability. In this context, metals/metal oxide doped electrospun membranes have grasped a great scientific interest as sustainable catalysts due to their enhanced catalytic activity and synergistic structure-property relationship of the doped material and the matrix. More specifically, the selectivity arising from the electronic properties and quantum mechanical interactions at the nanoscale of metal/metal oxide nanoparticles coupled with interactions at the electrospun membrane interfaces lead to such enhanced properties. This review article summarizes the applications of metals/metal doped electrospun membranes in different aspects of catalysis, such as thermocatalysis, photocatalysis, organocatalysis and electrocatalysis, with a particular focus on their sustainability. \u0000Keywords: Sustainable catalysis, metal/metal oxide doped catalysts, electrospinning, organocatalysis, photocatalysis","PeriodicalId":214405,"journal":{"name":"Vidyodaya Journal of Science","volume":"373 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122049384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.31357/vjs.v25i01.5925
K.G. Jayasekara, S.S.S.B.D.P Soysa, T.S. Suresh3, C.L. Goonasekara, K.M. Gunasekera
Dengue infection is a major health care problem in tropical and subtropical countries. The recently approved dengue vaccine has limitations, and there is no antiviral drug for treatment at present.For centuries plants and plant extracts have been used in traditional medicine for the treatment of various infections. The whole plant of Munronia pinnata, which has been used for treating fever patients in Sri Lankan traditional medicine, was tested for anti-dengue viral activity.The cytotoxicity assay of M. pinnata on Vero cells using 4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) revealed Maximum Nontoxic Dose (MNTD) as 125 μg/ml and 50% cytotoxic concentration (CC50) as 428.9 ± 21.55 μg/ml. Plaque reduction antiviral assay performed on dengue-4 virus infected Vero cells demonstrated half-maximal inhibitory concentration (IC50) as 26.12 ± 0.91 μg/ml. The selectivity index (SI) of Dengue infection is a major health care problem in tropical and subtropical countries. The recently approved dengue vaccine has limitations, and there is no antiviral drug for treatment at present.For centuries plants and plant extracts have been used in traditional medicine for the treatment of various infections. The whole plant of Munronia pinnata, which has been used for treating fever patients in Sri Lankan traditional medicine, was tested for anti-dengue viral activity.The cytotoxicity assay of M. pinnata on Vero cells using 4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) revealed Maximum Nontoxic Dose (MNTD) as 125 μg/ml and 50% cytotoxic concentration (CC50) as 428.9 ± 21.55 μg/ml. Plaque reduction antiviral assay performed on dengue-4 virus infected Vero cells demonstrated half-maximal inhibitory concentration (IC50) as 26.12 ± 0.91 μg/ml. The selectivity index (SI) of M. pinnata was 16.42.Based on the selectivity index, Munronia pinnata appears to be a viable candidate for identifying biologically active compounds with anti-dengue viral activity.Keywords: Dengue, Munronia pinnata, Antiviral, Plaque reduction Assay, Vero Cells was 16.42.Based on the selectivity index, Munronia pinnata appears to be a viable candidate for identifying biologically active compounds with anti-dengue viral activity. Keywords: Dengue, Munronia pinnata, Antiviral, Plaque reduction Assay, Vero Cells
{"title":"A Preliminary Study on the Anti-dengue Viral Activity of Munronia pinnata","authors":"K.G. Jayasekara, S.S.S.B.D.P Soysa, T.S. Suresh3, C.L. Goonasekara, K.M. Gunasekera","doi":"10.31357/vjs.v25i01.5925","DOIUrl":"https://doi.org/10.31357/vjs.v25i01.5925","url":null,"abstract":"Dengue infection is a major health care problem in tropical and subtropical countries. The recently approved dengue vaccine has limitations, and there is no antiviral drug for treatment at present.For centuries plants and plant extracts have been used in traditional medicine for the treatment of various infections. The whole plant of Munronia pinnata, which has been used for treating fever patients in Sri Lankan traditional medicine, was tested for anti-dengue viral activity.The cytotoxicity assay of M. pinnata on Vero cells using 4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) revealed Maximum Nontoxic Dose (MNTD) as 125 μg/ml and 50% cytotoxic concentration (CC50) as 428.9 ± 21.55 μg/ml. Plaque reduction antiviral assay performed on dengue-4 virus infected Vero cells demonstrated half-maximal inhibitory concentration (IC50) as 26.12 ± 0.91 μg/ml. The selectivity index (SI) of Dengue infection is a major health care problem in tropical and subtropical countries. The recently approved dengue vaccine has limitations, and there is no antiviral drug for treatment at present.For centuries plants and plant extracts have been used in traditional medicine for the treatment of various infections. The whole plant of Munronia pinnata, which has been used for treating fever patients in Sri Lankan traditional medicine, was tested for anti-dengue viral activity.The cytotoxicity assay of M. pinnata on Vero cells using 4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) revealed Maximum Nontoxic Dose (MNTD) as 125 μg/ml and 50% cytotoxic concentration (CC50) as 428.9 ± 21.55 μg/ml. Plaque reduction antiviral assay performed on dengue-4 virus infected Vero cells demonstrated half-maximal inhibitory concentration (IC50) as 26.12 ± 0.91 μg/ml. The selectivity index (SI) of M. pinnata was 16.42.Based on the selectivity index, Munronia pinnata appears to be a viable candidate for identifying biologically active compounds with anti-dengue viral activity.Keywords: Dengue, Munronia pinnata, Antiviral, Plaque reduction Assay, Vero Cells was 16.42.Based on the selectivity index, Munronia pinnata appears to be a viable candidate for identifying biologically active compounds with anti-dengue viral activity. \u0000Keywords: Dengue, Munronia pinnata, Antiviral, Plaque reduction Assay, Vero Cells","PeriodicalId":214405,"journal":{"name":"Vidyodaya Journal of Science","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131189757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.31357/vjs.v25i01.5928
C. Kaushalya, Taniya Darshani, S. Samarakoon, F. Fronczek, I. Perera, T. Perera
Neutral and cationic rhenium complexes provide both hydrophilic as well as hydrophobic properties due to the robustness of the tridentate ligand system of biphenyl appended dipicolylamine (N(SO2bip)dpa) and diethylenetriamine (N(SO2bip)dienH) coordinated to the [Re(CO)3]+ core, hold immense potential for the development of metal based anticancer drugs. This was achieved by the synthesis of two ligands (L1: N(SO2bip)dpa and L2: (N(SO2bip)dienH) and their corresponding Re complexes (C1: [Re(CO)3(N(SO2bip)dpa)]PF6 and C2: [Re(CO)3(N(SO2bip)dien)] in good yield and high purity. All four compounds were characterized by 1H NMR, UV-Vis, FTIR spectroscopies and L1, also by single crystal X-ray diffraction. The methylene protons observed as a singlet at (4.59 ppm) in a 1H NMR spectrum of L1 appear as two doublets (5.66 and 4.65 ppm) in the spectrum of C1. The appearance of NH signals at 3.48, 5.17 and 6.69 ppm in the 1H NMR spectrum of C2 confirm the coordination of L2 with Re. The stretching vibration frequencies depicted by the S-N bond at 923 cm-1 for L1 appear towards lower frequencies (821 cm-1) in an FTIR spectrum of C1, while the S-N bond at 943 cm-1 for L2 appears towards higher frequencies (968 cm-1) in C2. In silico assessment of drug likeliness revealed zero violations demonstrating a high likeliness of the ligands to be successful as drug leads. All four compounds have shown very low IC50 values against non-small cell lung cancer cells (NCI-H292). Therefore, L1, C1, L2 and C2 are promising novel compounds that can be further investigated as potential anticancer agents. Keywords: Rhenium Tricarbonyl, Sulfonamide, Anticancer, Fluorescence.
{"title":"Synthesis, Characterization and Remarkable Anticancer Activity of Rhenium Complexes Containing Biphenyl Appended NNN Donor Sulfonamide Ligands","authors":"C. Kaushalya, Taniya Darshani, S. Samarakoon, F. Fronczek, I. Perera, T. Perera","doi":"10.31357/vjs.v25i01.5928","DOIUrl":"https://doi.org/10.31357/vjs.v25i01.5928","url":null,"abstract":"Neutral and cationic rhenium complexes provide both hydrophilic as well as hydrophobic properties due to the robustness of the tridentate ligand system of biphenyl appended dipicolylamine (N(SO2bip)dpa) and diethylenetriamine (N(SO2bip)dienH) coordinated to the [Re(CO)3]+ core, hold immense potential for the development of metal based anticancer drugs. This was achieved by the synthesis of two ligands (L1: N(SO2bip)dpa and L2: (N(SO2bip)dienH) and their corresponding Re complexes (C1: [Re(CO)3(N(SO2bip)dpa)]PF6 and C2: [Re(CO)3(N(SO2bip)dien)] in good yield and high purity. All four compounds were characterized by 1H NMR, UV-Vis, FTIR spectroscopies and L1, also by single crystal X-ray diffraction. The methylene protons observed as a singlet at (4.59 ppm) in a 1H NMR spectrum of L1 appear as two doublets (5.66 and 4.65 ppm) in the spectrum of C1. The appearance of NH signals at 3.48, 5.17 and 6.69 ppm in the 1H NMR spectrum of C2 confirm the coordination of L2 with Re. The stretching vibration frequencies depicted by the S-N bond at 923 cm-1 for L1 appear towards lower frequencies (821 cm-1) in an FTIR spectrum of C1, while the S-N bond at 943 cm-1 for L2 appears towards higher frequencies (968 cm-1) in C2. In silico assessment of drug likeliness revealed zero violations demonstrating a high likeliness of the ligands to be successful as drug leads. All four compounds have shown very low IC50 values against non-small cell lung cancer cells (NCI-H292). Therefore, L1, C1, L2 and C2 are promising novel compounds that can be further investigated as potential anticancer agents. \u0000Keywords: Rhenium Tricarbonyl, Sulfonamide, Anticancer, Fluorescence.","PeriodicalId":214405,"journal":{"name":"Vidyodaya Journal of Science","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128577714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biochar is a carbon-rich material resulting from the pyrolysis of plant and animal biomass. Biochar has a long history as a soil amendment for centuries since the Mayan civilization. Attaining sustainability in agriculture is not easy; however, the addition of biochar may reduce the adverse effects of numerous malpractices in conventional agriculture. Biochar benefits soil physicochemical properties such as soil bulk density, aggregate stability, porosity, water holding capacity and soil organic carbon content. However, it is essential to focus on the negative aspects of biochar in terms of atmospheric emissions during the production and occupational health and safety at the time of use. Still, there are many benefits and detriments of the application of biochar, i.e., the priming effect; thus, this review highlights the importance of further research on the application of biochar as a soil amendment. It has been understood that the lack of long-term field studies in various soils using commercially produced biochar may restrict the knowledge of biochar's true potential and effect on soil nutrient dynamics, microbial structure, and crop yield. Keywords: Land degradation, Biochar, Nutrient retention, Soil quality, Microbial community
{"title":"Benefits of Biochar Addition in a Sustainable Agriculture Practice: Soil Nutrients Dynamics, Enzyme Activities and Plant Growth","authors":"Viraj Gunarathnea, Tharanga Bandara, Sammani Ramanayaka, Meththika Vithanage","doi":"10.31357/vjs.v25i01.5921","DOIUrl":"https://doi.org/10.31357/vjs.v25i01.5921","url":null,"abstract":"Biochar is a carbon-rich material resulting from the pyrolysis of plant and animal biomass. Biochar has a long history as a soil amendment for centuries since the Mayan civilization. Attaining sustainability in agriculture is not easy; however, the addition of biochar may reduce the adverse effects of numerous malpractices in conventional agriculture. Biochar benefits soil physicochemical properties such as soil bulk density, aggregate stability, porosity, water holding capacity and soil organic carbon content. However, it is essential to focus on the negative aspects of biochar in terms of atmospheric emissions during the production and occupational health and safety at the time of use. Still, there are many benefits and detriments of the application of biochar, i.e., the priming effect; thus, this review highlights the importance of further research on the application of biochar as a soil amendment. It has been understood that the lack of long-term field studies in various soils using commercially produced biochar may restrict the knowledge of biochar's true potential and effect on soil nutrient dynamics, microbial structure, and crop yield. \u0000Keywords: Land degradation, Biochar, Nutrient retention, Soil quality, Microbial community","PeriodicalId":214405,"journal":{"name":"Vidyodaya Journal of Science","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125347987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Modern agriculture practices play a vital role in fulfilling the doubling food demands of the increasing population. In particular, several attempts have been made to enhance the nutrient supply and plant uptake process in different growth stages of plants, but little effort has been made to enhance the nutrient status of the seeds at the seedling stage. At this stage of growth, phosphorus is the most essential nutrient, and the requirement is high, while nitrogen requirement is very low. This study focuses on developing a seed coating containing urea-modified hydroxyapatite nanocomposite to supply N and P to the seedlings in a controlled manner throughout the early growth stage. A nanohybrid based on urea-modified hydroxyapatite was synthesized using an in-situ sol-gel method and further combined with an alginate/cellulose polymer to develop the coating. Seed coating was realized using a dip coating method containing calcium chloride as the cross-linking agent. Seed germination experiments were conducted under laboratory conditions according to a randomized complete block design under constant light conditions, controlled humidity, and temperature. The structural features of the nanocomposite were studied using powder X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopic data was used to analyze the morphology. The formation of HA nanoparticles was confirmed by powder x-ray diffraction patterns that revealed the characteristic peaks for (002), (211), (300), and (202) planes of HA. Furthermore, the successful insertion of urea into the HA lattice was corroborated by both the powder X-ray diffraction and Fourier transform infrared spectroscopic techniques. Nanocomposite coatings of 50 -100 μm demonstrated excellent compatibility with the surfaces of the seeds. Seed coating composed of hydroxyapatite-urea (1:0.3) treatment revealed an increase of 124.6%, 147.6%, 100%, and 166.7% in average biomass, root length, number of roots, and maximum plant width, respectively, compared to the control, after 21 days of planting.Keywords: Urea Modified Hydroxyapatite, Nanocomposite, Alginate, Carboxymethyl Cellulose, Seed Coating, Germination.
{"title":"Urea-Hydroxyapatite-Polymer Nanohybrids as Seed Coatings for Enhanced Germination","authors":"Dasuni Pabodha, Latheesha Abeywardana, Chanaka Sandaruwan, Lasantha Herath, Gayan Priyadarshana","doi":"10.31357/vjs.v25i01.5924","DOIUrl":"https://doi.org/10.31357/vjs.v25i01.5924","url":null,"abstract":"Modern agriculture practices play a vital role in fulfilling the doubling food demands of the increasing population. In particular, several attempts have been made to enhance the nutrient supply and plant uptake process in different growth stages of plants, but little effort has been made to enhance the nutrient status of the seeds at the seedling stage. At this stage of growth, phosphorus is the most essential nutrient, and the requirement is high, while nitrogen requirement is very low. This study focuses on developing a seed coating containing urea-modified hydroxyapatite nanocomposite to supply N and P to the seedlings in a controlled manner throughout the early growth stage. A nanohybrid based on urea-modified hydroxyapatite was synthesized using an in-situ sol-gel method and further combined with an alginate/cellulose polymer to develop the coating. Seed coating was realized using a dip coating method containing calcium chloride as the cross-linking agent. Seed germination experiments were conducted under laboratory conditions according to a randomized complete block design under constant light conditions, controlled humidity, and temperature. The structural features of the nanocomposite were studied using powder X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopic data was used to analyze the morphology. The formation of HA nanoparticles was confirmed by powder x-ray diffraction patterns that revealed the characteristic peaks for (002), (211), (300), and (202) planes of HA. Furthermore, the successful insertion of urea into the HA lattice was corroborated by both the powder X-ray diffraction and Fourier transform infrared spectroscopic techniques. Nanocomposite coatings of 50 -100 μm demonstrated excellent compatibility with the surfaces of the seeds. Seed coating composed of hydroxyapatite-urea (1:0.3) treatment revealed an increase of 124.6%, 147.6%, 100%, and 166.7% in average biomass, root length, number of roots, and maximum plant width, respectively, compared to the control, after 21 days of planting.Keywords: Urea Modified Hydroxyapatite, Nanocomposite, Alginate, Carboxymethyl Cellulose, Seed Coating, Germination.","PeriodicalId":214405,"journal":{"name":"Vidyodaya Journal of Science","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115935823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Curd is a dairy product produced via way of means of coagulating milk in a process known as curdling. The objective of this current study was to prepare curd traditionally in the laboratory and identify Lactobacilli species with potential probiotic activities. Cow and goat milk was collected, and curd was prepared by adding lime and starter culture in different amounts. Among prepared curd samples, best quality curd was selected, and from the selected curd samples, lactic acid bacteria were isolated and subsequent subculturing was carried out, and ten different Lactobacilli isolates were obtained and identified based on morphological, physiological and biochemical characteristics.Isolates were subjected to test the antagonistic effect among the Lactobacilli isolates and against selected bacterial strains by standard agar well diffusion method. Antibiotic sensitivity test by disc method was carried out by using antibiotics and the production of lactic acid by titration method.Ten different Lactobacilli isolates were classified into three different genera Lactobacillus sp., Pediococcus sp. and Leuconostoc sp. Growth of all Lactobacilli was observed under acidic and neutral pH. Lactic acid bacteria exhibited different tolerant levels to bile salt. No antagonistic effect was observed among the Lactobacilli isolates. But 80% of lactobacilli isolates had antibacterial activity on selected bacterial species. The growth of Bacillus sp. was predominantly inhibited by Lactic acid bacterial isolates (90%), Pseudomonas aeruginosa (30%), Proteus sp. and Staphylococcus aureus (50%) and E.coli (30%). Lactobacillus sp. (CL2) predominantly inhibited all tested bacteria (100%). Growth of the Lactobacilli isolates was inhibited by tested antibiotics except for Lactobacillus sp. (CC3) was resistant to bacitracin only. All of the Lactic acid bacterial isolates produced a considerable amount of lactic acid. Under the controlled conditions, the Lactobacillus sp. (GL1) produced a significantly high level of lactic acid (0. 315%), whereas Lactobacillus sp. (CL3) produced less amount of lactic acid (0.099%). Keywords: Curd, Lactic acid bacteria, Antagonistic effect, Antibacterial sensitivity, Lactic acid
{"title":"Occurrence of Lactobacilli in the Traditional Preparation of Curd","authors":"Sarany Uthayakumar, Arulanantham Christie Thavaranjit, Gowri Rajkumar","doi":"10.31357/vjs.v25i01.5927","DOIUrl":"https://doi.org/10.31357/vjs.v25i01.5927","url":null,"abstract":"Curd is a dairy product produced via way of means of coagulating milk in a process known as curdling. The objective of this current study was to prepare curd traditionally in the laboratory and identify Lactobacilli species with potential probiotic activities. Cow and goat milk was collected, and curd was prepared by adding lime and starter culture in different amounts. Among prepared curd samples, best quality curd was selected, and from the selected curd samples, lactic acid bacteria were isolated and subsequent subculturing was carried out, and ten different Lactobacilli isolates were obtained and identified based on morphological, physiological and biochemical characteristics.Isolates were subjected to test the antagonistic effect among the Lactobacilli isolates and against selected bacterial strains by standard agar well diffusion method. Antibiotic sensitivity test by disc method was carried out by using antibiotics and the production of lactic acid by titration method.Ten different Lactobacilli isolates were classified into three different genera Lactobacillus sp., Pediococcus sp. and Leuconostoc sp. Growth of all Lactobacilli was observed under acidic and neutral pH. Lactic acid bacteria exhibited different tolerant levels to bile salt. No antagonistic effect was observed among the Lactobacilli isolates. But 80% of lactobacilli isolates had antibacterial activity on selected bacterial species. The growth of Bacillus sp. was predominantly inhibited by Lactic acid bacterial isolates (90%), Pseudomonas aeruginosa (30%), Proteus sp. and Staphylococcus aureus (50%) and E.coli (30%). Lactobacillus sp. (CL2) predominantly inhibited all tested bacteria (100%). Growth of the Lactobacilli isolates was inhibited by tested antibiotics except for Lactobacillus sp. (CC3) was resistant to bacitracin only. All of the Lactic acid bacterial isolates produced a considerable amount of lactic acid. Under the controlled conditions, the Lactobacillus sp. (GL1) produced a significantly high level of lactic acid (0. 315%), whereas Lactobacillus sp. (CL3) produced less amount of lactic acid (0.099%).\u0000Keywords: Curd, Lactic acid bacteria, Antagonistic effect, Antibacterial sensitivity, Lactic acid","PeriodicalId":214405,"journal":{"name":"Vidyodaya Journal of Science","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114259015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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