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Auf dem Weg zur Herzbildgebung – Max Levy Dorn und die Entwicklung der Orthoröntgenografie. 马克斯·列维·多恩和x光片的发展。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2026-01-01 Epub Date: 2025-12-16 DOI: 10.1055/a-2630-4115
Uwe Busch, Heinz-Peter Schlemmer
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引用次数: 0
Value of CT-derived Fractional Flow Reserve in the Context of Outpatient Cardiac CT in Germany: A Propensity Score Matched Analysis. 在德国门诊心脏CT背景下CT衍生的分数血流储备的价值:倾向评分匹配分析。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-17 DOI: 10.1055/a-2760-5485
Dennis Rottländer, Cara Fischer, Yazan Mohsen, Melchior Seyfarth, Marc Horlitz, Paul Martin Bansmann

Coronary artery disease (CAD) remains one of the leading causes of death in Germany. Since outpatient reimbursement for cardiac computed tomography angiography (CCTA) became available in 2024, non-invasive diagnostics have gained importance. CT-derived fractional flow reserve (FFR-CT) may increase the specificity of CCTA and reduce invasive procedures.In this retrospective analysis, 640 consecutive patients with coronary stenosis >25% were included in outpatient CCTA. Among them, 107 underwent additional FFR-CT. After propensity score matching, two cohorts of 105 patients each were available for comparison. The primary endpoint was the positive predictive value (PPV) for hemodynamically relevant stenoses.Based on propensity score matching, FFR-CT showed a PPV of 88% compared to 73% in the group without FFR-CT. Patients with nonpathological FFR-CT results were mainly managed conservatively, whereas pathological values led to revascularization in more than 70%. In the control group without FFR-CT, invasive coronary angiographies without coronary intervention were significantly more frequent (27%). Correlation between FFR-CT and invasive FFR was strong (r = 0.92; ICC = 0.95).Integration of FFR-CT in outpatient CCTA seems to improve diagnostic accuracy and reduce invasive procedures. It has the potential to combine anatomical and functional information and optimize treatment decisions in stable CAD. · FFR-CT has the potential to increase diagnostic accuracy and reduce invasive coronary angiographies.. · FFR-CT has a higher positive predictive value than CCTA.. · The correlation between FFR-CT and invasive FFR was high.. · In cases of pathological FFR-CT, revascularization was performed in >70% of patients. · Rottländer D, Fischer C, Mohsen Y et al. Value of CT-derived Fractional Flow Reserve in the Context of Outpatient Cardiac CT in Germany: A Propensity Score Matched Analysis. Rofo 2025; DOI 10.1055/a-2760-5485.

冠状动脉疾病(CAD)仍然是德国的主要死亡原因之一。自2024年心脏计算机断层血管造影(CCTA)的门诊报销以来,非侵入性诊断变得越来越重要。ct衍生的血流储备分数(FFR-CT)可以增加CCTA的特异性并减少侵入性手术。在这项回顾性分析中,640例冠状动脉狭窄患者连续被纳入门诊CCTA。其中107例追加FFR-CT检查。倾向评分匹配后,两组各105例患者可用于比较。主要终点是血流动力学相关狭窄的阳性预测值(PPV)。根据倾向评分匹配,FFR-CT显示PPV为88%,而未进行FFR-CT的组为73%。非病理性FFR-CT结果的患者主要采用保守治疗,而病理值导致70%以上的血运重建术。在没有FFR-CT的对照组中,没有冠状动脉介入的有创冠状动脉造影明显更频繁(27%)。FFR- ct与侵袭性FFR相关性较强(r = 0.92; ICC = 0.95)。FFR-CT在门诊CCTA中的整合似乎提高了诊断准确性并减少了侵入性手术。它有可能结合解剖和功能信息,优化稳定CAD的治疗决策。·FFR-CT具有提高诊断准确性和减少侵入性冠状动脉造影的潜力。·FFR-CT的阳性预测值高于CCTA。·FFR- ct与侵袭性FFR相关性高。·病理性FFR-CT病例中,70%的患者行血运重建术。·Rottländer D, Fischer C, Mohsen Y等。在德国门诊心脏CT背景下CT衍生的分数血流储备的价值:倾向评分匹配分析。Rofo 2025;DOI 10.1055 / - 2760 - 5485。
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引用次数: 0
Requirements for Physico-Technical Quality Assurance in the Framework of Early Detection of Lung Cancer. 肺癌早期检测框架下的物理技术质量保证要求
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-17 DOI: 10.1055/a-2597-0689
Rainer Eßeling, Mathis Konrad, Hannah Prokesch, Bernhard Renger, Constantin Schareck, Georg Stamm

According to the text of the Lung Cancer Screening Ordinance on the permissibility of using low-dose computed tomography to screen smokers (LuKrFrühErkV, §7 Quality Assurance, 1), the "radiation protection officer must establish and operate a comprehensive quality assurance system. This must take account of organizational, medical, and technical aspects, in particular [...] 2. the diagnostic image quality of the computed tomography scan, 3. the physical-technical parameters for the acquisition of the computed tomography scan [...]". The German Radiological Society (DRG) considers itself responsible for making recommendations regarding the implementation of such a quality assurance system, in order to provide users with legal certainty and ensure patient safety. The DRG's Physics and Technology Working Group has thus identified the main issues regarding quality assurance for technology, outlined the related challenges, and proposed potential areas for future investigation and resolution (see sections I-V). Existing quality assurance measures for technology must be checked for their suitability with regard to a low-dose screening program and adapted, if necessary. Complex additional constancy tests and the use of special (anthropomorphic) phantoms are not currently considered necessary. The tasks of manufacturers and medical physicists were refined further, and it was recommended that reference centers should be established as soon as possible. · Constancy testing methods for CT are largely sufficient for lung cancer screening.. · Daily air calibration is recommended to ensure consistent image quality.. · Anthropomorphic phantoms are not currently required for quality assurance.. · Manufacturers must provide protocols that meet LuKrFrühErkV requirements.. Eßeling R, Konrad M, Prokesch H et al. Requirements for Physico-Technical Quality Assurance in the Framework of Early Detection of Lung Cancer. Rofo 2026; DOI 10.1055/a-2597-0689.

根据肺癌筛查条例关于使用低剂量计算机断层扫描筛查吸烟者的许可的文本(lukrfr herkv,§7质量保证,1),“辐射防护官员必须建立和运行一个全面的质量保证体系。这必须考虑到组织、医疗和技术方面,特别是[…]) 2。2 .计算机断层扫描的诊断图像质量;获取计算机断层扫描的物理技术参数[…]”。德国放射学会(DRG)认为自己有责任就实施这种质量保证体系提出建议,以便为用户提供法律确定性并确保患者安全。DRG的物理和技术工作组因此确定了有关技术质量保证的主要问题,概述了相关挑战,并提出了未来调查和解决的潜在领域(见第I-V节)。必须检查现有的技术质量保证措施是否适合低剂量筛查计划,并在必要时进行调整。目前认为没有必要进行复杂的附加恒常性测试和使用特殊的(拟人的)幽灵。进一步细化了制造商和医学物理学家的任务,建议尽快建立参考中心。·CT的恒常性检测方法在很大程度上足以用于肺癌筛查。·建议每天进行空气校准,以确保图像质量一致。·拟人化的幻影目前不需要用于质量保证。·制造商必须提供符合lukrfr herkv要求的协议。Eßeling R, Konrad M, Prokesch H等。肺癌早期检测框架下的物理技术质量保证要求Rofo 2026;DOI 10.1055 / - 2597 - 0689。
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引用次数: 0
[Case-Report: Rare hepatic epithelioid angiomyolipoma (HEAML) should be considered in the differential diagnosis of liver tumors in otherwise healthy livers.] [病例报告:罕见肝上皮样血管平滑肌脂肪瘤(HEAML)在其他健康肝脏肿瘤的鉴别诊断中应予以考虑。]
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-17 DOI: 10.1055/a-2742-6077
Martin Kellner, Peter Kappl, Pompiliu Piso, Niels Zorger
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引用次数: 0
Rectification: the well-known "hand with gunshot" radiograph signed by M.I. Pupin (1858-1935) and published in 1931 is a forgery. 更正:1931年出版的著名的“枪击之手”x光片是伪造的,署名是m.i.p upin(1858-1935)。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-17 DOI: 10.1055/a-2742-1763
Jean-Francois Monville, Robert Ferdinand Dondelinger

The well-known "hand with gunshot" X-ray bearing the signature of M.I. Pupin from Columbia College New York is widely recognized in the literature as being the first radiograph acquired with the use of an intensifying screen.Personal research in the New York City daily newspapers from 1896 and at Columbia University allowed us to establish that Pupin took two X-rays of a "hand with gunshot" in a patient on February 15 and 19, 1896. The first X-ray is preserved among the Pupin papers at Columbia University, and the second radiograph was published in an American magazine in March 1896. In 1974, the original radiographic plate of the X-ray performed on February 19 was discovered. In 1930 or shortly before, Pupin signed a contemporary X-ray of a "hand with gunshot", which is incompatible with the historical X-rays. This X-ray was made public in 1931,1965, and 1969, with the false claim that it was the first X-ray acquired using an intensifying screen in 1896.The "hand with gunshot" X-ray signed by Pupin around 1930 is a crude forgery of the X-ray he made on February 19, 1896. This X-ray has since been published many times and has been erroneously taken in good faith for the original. The historical X-rays remained ignored. · This paper establishes that the renowned "hand with gunshot" X-ray signed by M.I. Pupin is a forgery.. · Monville J-F., Dondelinger RF. Rectification: the well-known "hand with gunshot" radiograph signed by M.I. Pupin (1858-1935) and published in 1931 is a forgery. Rofo 2025; DOI 10.1055/a-2742-1763.

著名的“枪击之手”x光片上有纽约哥伦比亚学院的m.i.p uppin的签名,在文献中被广泛认为是第一张使用强化屏幕获得的x光片。通过对1896年纽约市日报和哥伦比亚大学的个人研究,我们确定了普平在1896年2月15日和19日为一位病人拍了两张“有枪伤的手”的x光片。第一张x光照片被保存在哥伦比亚大学的普平论文中,第二张x光照片于1896年3月发表在美国的一本杂志上。1974年2月19日拍摄的x光片原片被发现。1930年或更早的时候,普平在一张同时代的x光照片上签名,这张x光照片显示的是“有枪的手”,这与历史上的x光照片不相容。这张x光片在1931年、1965年和1969年被公开,虚假地声称这是1896年使用强化屏幕获得的第一张x光片。普平在1930年左右签名的“枪击手”x光片是他1896年2月19日拍摄的x光片的粗糙伪造品。此后,这张x光照片被多次发表,并被误认为是原图。历史上的x射线仍然被忽视。·本文证实了著名的“枪击之手”x光照片是伪造的。·蒙维尔J-F。Dondelinger RF。更正:1931年出版的著名的“枪击之手”x光片是伪造的,署名是m.i.p upin(1858-1935)。Rofo 2025;DOI 10.1055 / - 2742 - 1763。
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引用次数: 0
Digital Transformation and Artificial Intelligence in Radiology: Challenges and Opportunities for Clinical Practice, Research, and the Next Generation. 放射学的数字化转型和人工智能:临床实践、研究和下一代的挑战和机遇。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-17 DOI: 10.1055/a-2741-9717
Emily Hoffmann, Peter Bannas, Nadine Bayerl, Clemens C Cyran, Matthias Dietzel, Michel Eisenblätter, Ingrid Hilger, Caroline Jung, Fabian Kiessling, Claudius Sebastian Mathy, Lukas Müller, Fritz Schick, Franz Wegner, Tobias Bäuerle, Lisa Adams

Radiology is at the center of the digital transformation of the healthcare system. As a highly digital field, radiology is well-suited for the early implementation and critical evaluation of innovative technologies, such as artificial intelligence (AI). This review aims to comprehensively and distinctly present the opportunities and challenges of digital transformation in radiology, focusing on clinical applications, research, and promoting young talents.This narrative review is based on selective evaluation of relevant scientific literature and publications from the last 10 years. Relevant German- and English-language articles on the digital transformation of radiology were considered, particularly those addressing digital infrastructure, artificial intelligence, ethical and regulatory frameworks, and education and training.Digitalization offers significant opportunities for radiology. In addition to advancing imaging procedures and automating image analysis with AI, digitalization optimizes workflows, enables personalized diagnostics, and fosters new care models, such as teleradiology. However, there are also key challenges: Data protection issues, a lack of standardization, insufficient validation, and regulatory hurdles are hindering its widespread implementation in hospitals. To future-proof radiology, it is essential to promote young talent and incorporate digital skills in the curriculum. · Due to its digital structure, radiology is particularly well-suited to integrating new medical technologies.. · Some AI-powered applications have been adopted in everyday clinical practice but they require further validation.. · A key task for the future is systematically training prospective radiologists in digital skills.. · Hoffmann E, Bannas P, Bayerl N et al. Digital Transformation and Artificial Intelligence in Radiology: Challenges and Opportunities for Clinical Practice, Research, and the Next Generation. Rofo 2025; DOI 10.1055/a-2741-9717.

放射学处于医疗保健系统数字化转型的中心。作为一个高度数字化的领域,放射学非常适合人工智能(AI)等创新技术的早期实施和关键评估。本文旨在全面、清晰地展示放射学数字化转型的机遇和挑战,重点关注临床应用、研究和培养年轻人才。这篇叙述性综述是基于对过去10年相关科学文献和出版物的选择性评估。会议审议了关于放射学数字化转型的相关德文和英文文章,特别是涉及数字基础设施、人工智能、道德和监管框架以及教育和培训的文章。数字化为放射学提供了重要的机会。除了推进成像程序和利用人工智能自动化图像分析之外,数字化还优化了工作流程,实现了个性化诊断,并促进了新的护理模式,如远程放射学。然而,也存在一些关键挑战:数据保护问题、缺乏标准化、验证不足以及监管障碍阻碍了其在医院的广泛实施。为了面向未来的放射学,培养年轻人才并将数字技能纳入课程至关重要。·由于其数字化结构,放射学特别适合整合新的医疗技术。·一些人工智能驱动的应用已被用于日常临床实践,但需要进一步验证。·未来的一项关键任务是系统地培训未来的放射科医生的数字技能。·Hoffmann E, Bannas P, Bayerl N等。放射学的数字化转型和人工智能:临床实践、研究和下一代的挑战和机遇。Rofo 2025;DOI 10.1055 / - 2741 - 9717。
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引用次数: 0
[Nitrous oxide use - an increasing cause of myelopathies]. [使用一氧化二氮-脊髓病的一个日益增加的原因]。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-17 DOI: 10.1055/a-2739-5370
Ludger Feyen, Dominic Ochonski, Alexandr Cernei
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引用次数: 0
Enteral contrast administration in abdominal computed tomography - Expert recommendations from the Abdominal Workgroup of the German Roentgen Society. 腹部计算机断层扫描中的肠内造影剂应用——德国伦琴学学会腹部工作组的专家建议。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-08 DOI: 10.1055/a-2750-0204
Jan-Christoph Stadelmann, Lars Grenacher, Markus S Juchems, Guido Kukuk, Thomas Lauenstein, Andreas G Schreyer, Johannes Wessling, Kristina I Ringe

There is a lack of clear recommendations regarding enteral contrast agent administration in the context of abdominal computed tomography (CT). A survey among members of the German Radiological Society (DRG) identified a very heterogeneous and indication-specific approach in the clinical routine. The goal of this study is to develop generally applicable recommendations.Recommendations for enteral contrast agent administration were developed by members of the Abdominal Workgroup within the DRG, using methodology comparable to that of an S1 guideline with informal consensus. Relevant clinical indications were systematically identified, categorized, and assessed considering current evidence in the literature and guidelines.There are specific clinical scenarios in which enteral contrast is indicated. Respective recommendations are presented in terms of good clinical practice (GCP). In this context, especially the administration of positive enteral contrast agents for abdominal CT examination is obsolete for many clinical indications. · For many indications, enteral contrast agent administration is not necessary. · In the case of esophageal or gastric tumors, enteral contrast should be achieved using the "hydro-technique". · Positive enteral contrast agents are primarily recommended for diagnosis of gastrointestinal fistulas and anastomoses. · Stadelmann J, Grenacher L, Juchems MS et al. Enteral contrast administration in abdominal computed tomography - Expert recommendations from the Abdominal Workgroup of the German Roentgen Society. Rofo 2025; DOI 10.1055/a-2750-0204.

在腹部计算机断层扫描(CT)的背景下,关于肠内注射造影剂缺乏明确的建议。在德国放射学会(DRG)成员中进行的一项调查确定了临床常规中非常不均匀和适应症特异性的方法。本研究的目的是提出普遍适用的建议。关于肠内造影剂给药的建议是由DRG的腹部工作组成员制定的,使用的方法与非正式共识的S1指南相当。考虑文献和指南中的现有证据,系统地确定、分类和评估相关的临床适应症。在一些特殊的临床情况下,需要进行肠内对比检查。根据良好临床实践(GCP)提出了相应的建议。在这种情况下,特别是在腹部CT检查中使用阳性肠内对比剂对于许多临床适应症来说已经过时了。·对于许多适应症,不需要肠内注射造影剂。·对于食管或胃肿瘤,应采用“水技术”进行肠内造影剂。·阳性肠内造影剂主要推荐用于胃肠道瘘管和吻合口的诊断。·Stadelmann J, Grenacher L, juchem MS等。腹部计算机断层扫描中的肠内造影剂应用——德国伦琴学学会腹部工作组的专家建议。Rofo 2025;DOI 10.1055 / - 2750 - 0204。
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引用次数: 0
[Severe lower abdominal pain in a teenager - just 'painfull periods'?] 青少年严重的下腹部疼痛——只是“痛经”?]
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-08 DOI: 10.1055/a-2739-5424
Franziska Müller-Reichart, Fabian Kleindiek, Clemens Benoit
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引用次数: 0
Long/Post-Covid - An Interdisciplinary Challenge. 长期/后疫情:跨学科的挑战。
IF 1.7 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-12-01 Epub Date: 2025-05-23 DOI: 10.1055/a-2578-1363
Emil C Reisinger, Hilte Geerdes-Fenge, Christine Wossidlo, Hanka Arndt

In this overview we summarize the current state of scientific knowledge on the epidemiology, etiology, clinical symptoms and therapy of post-COVID disease.The study is based on a search of the scientific literature available on PubMed and on our own clinical experience in the post-COVID outpatient clinic.The prevalence of post-COVID disease varies greatly depending on the survey method used. The symptoms of post-COVID are manifold, but fatigue, cardiopulmonary complaints, cognitive deficit, and pain syndromes are prominent. There are currently no surefire symptoms or specific markers that prove the presence of the disease. Therefore, diagnosis is often based on an exclusion of other diagnoses, which requires good interdisciplinary cooperation. Therapy for post-COVID disease is also not specific but is always individual and symptom-oriented. There have been various attempts to explain the pathogenesis of post-COVID, but the mechanisms behind the development of the condition have not yet been conclusively clarified. Persistence of the virus or of viral proteins may cause protracted infection or autoimmunity. Infection and inflammation of the endothelium of the small vessels and the hypercoagulation associated with this may lead to local cytokine dysregulation and organ damage. Further clarification of the pathogenesis of post-COVID and the establishment of effective diagnostic tools and therapeutic approaches are urgently needed. · Post-COVID is a commonly reported condition with variable symptoms. · Interdisciplinary exclusion of other diagnoses and therapy planning are important. · Clarification of pathogenesis and establishment of diagnostic markers are urgently needed. · Reisinger EC, Geerdes-Fenge H, Wossidlo C et al. Long/Post-Covid - An Interdisciplinary Challenge. Rofo 2025; 197: 1388-1393.

本文综述了covid - 19后疾病的流行病学、病因、临床症状和治疗等方面的科学知识现状。这项研究是基于对PubMed上可获得的科学文献的搜索,以及我们自己在covid后门诊诊所的临床经验。covid - 19后疾病的患病率因使用的调查方法而异。新冠肺炎后的症状是多种多样的,但疲劳、心肺不适、认知障碍和疼痛综合征最为突出。目前还没有确定的症状或特定的标志物来证明这种疾病的存在。因此,诊断往往是在排除其他诊断的基础上进行的,这需要良好的跨学科合作。covid - 19后疾病的治疗也不是特异性的,而是始终以个体和症状为导向的。关于新冠肺炎后发病机制的解释有多种尝试,但其发病机制尚未得到明确解释。病毒或病毒蛋白的持续存在可引起长期感染或自身免疫。小血管内皮的感染和炎症以及与此相关的高凝可导致局部细胞因子失调和器官损伤。迫切需要进一步明确新冠肺炎后发病机制,建立有效的诊断工具和治疗方法。·新冠肺炎后是一种常见的症状,症状多种多样。·跨学科排除其他诊断和治疗计划是重要的。·迫切需要明确发病机制,建立诊断标志物。·Reisinger EC, Geerdes-Fenge H, Wossidlo C等。长期/后疫情:跨学科的挑战。Rofo 2025;DOI 10.1055 / - 2578 - 1363。
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引用次数: 0
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