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New insight in psychotic cannabis withdrawal: case series and brief overview. 精神病性大麻戒断的新见解:病例系列和简要概述。
IF 1 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-11-01 DOI: 10.1708/4386.43840
Valerio Ricci, Domenico De Berardis, Giovanni Martinotti, Giuseppe Maina

Background: Cannabis is the most used recreational drug worldwide. Its use can increase the risk of developing psychotic disorders and exacerbate their course. However, little is known about the relationship between psychosis and withdrawal and the literature is still scarce.

Case presentation: In this study, based on an analysis of 4 patients referred to our mental health department and evaluated between 2019 and 2023, we describe psychotic features emerged after abrupt cannabis withdrawal and we attempt to explore its characteristics.

Conclusion: Although it is difficult to show specific mechanisms underlying the psychopathological alterations in cannabis withdrawal induced psychosis, it is clear that this serious clinical picture could be a risk factor for precipitating psychosis especially in a vulnerable group of patients. Clinicians should be aware of the possibility of a higher risk of psychotic onset associated not only with chronic cannabis use but also with its abrupt cessation.

背景:大麻是世界上使用最多的娱乐性药物。它的使用会增加患精神疾病的风险,并加剧其病程。然而,关于精神病和戒断之间的关系知之甚少,文献仍然很少。病例介绍:在本研究中,基于对2019年至2023年间转介到我们精神卫生部门并进行评估的4例患者的分析,我们描述了突然戒断大麻后出现的精神病特征,并试图探讨其特征。结论:虽然很难显示大麻戒断诱导精神病的精神病理改变的具体机制,但很明显,这种严重的临床症状可能是诱发精神病的危险因素,特别是在弱势群体中。临床医生应该意识到精神病发作的高风险不仅与慢性大麻使用有关,而且与其突然停止有关。
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引用次数: 0
When the Pros become Cons in people with obsessive-compulsive disorder. 当强迫症患者的优点变成缺点时。
IF 1 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-11-01 DOI: 10.1708/4386.43841
Gherardo Mannino

Although descriptive psychopathology of obsessive-compulsive disorder (OCD) is well-established, this disorder still presents very enigmatic and puzzling aspects. Hence the usefulness for further contributions to better clarify the picture. For example, one of the most problematic manifestations of OCD consists in pathological doubt, whose origin, however, remains unclear. For this purpose, a psychopathological analysis of several cases of OCD, in which decisional uncertainty is involved, is conducted, as well as a rereading of a famous case by Freud. As a result, the existence of a new psychological phenomenon observable in OCD people is suggested. It is proposed to call it: "incompatibility perceived between unbiased commitment and satisfaction for an unexpected and effortless personal benefit" (ICB). In fact, when an OCD subject experiences a sense of commitment, be it interpersonal or impersonal, he/she will experience the satisfaction for an unexpected and effortless benefit that results from the commitment, as incompatible with the commitment itself. As result, the subject will consider the satisfaction for the benefit as true but inacceptable, whereas he/she will consider the sense of commitment as desirable but as false. This phenomenon not only seems to explain at least some cases of indecision typical of OCD, but sheds new light on some important explanatory concepts, such as 'ambivalence', 'self-ambivalence' and 'fear of oneself', called into question over time precisely to explain the varied psychopathology of OCD. Finally, it also seems to have important implications for psychotherapy.

尽管强迫症(OCD)的描述性精神病理学已得到充分证实,但这种疾病仍然呈现出非常神秘和令人费解的一面。因此,需要更多的研究成果来更好地澄清这一问题。例如,强迫症最棘手的表现之一是病态怀疑,但其起源至今仍不清楚。为此,我们对几个涉及决策不确定性的强迫症病例进行了精神病理学分析,并重读了弗洛伊德的一个著名病例。结果,提出了一种在强迫症患者身上可以观察到的新的心理现象。建议将其称为"无偏见的承诺和对意外的、不费吹灰之力的个人利益的满足感之间的不相容性"(ICB)。事实上,当强迫症患者体验到一种承诺感时,无论是人与人之间的还是人与人之间的,他/她都会体验到由承诺而产生的对意外的、毫不费力的利益的满足感,这种满足感与承诺本身是不相容的。因此,受试者会认为对利益的满足是真实的,但不能接受,而他/她会认为承诺感是可取的,但却是虚假的。这一现象似乎不仅至少可以解释强迫症中某些典型的优柔寡断的情况,而且为一些重要的解释性概念,如 "矛盾"、"自我矛盾 "和 "对自己的恐惧 "提供了新的启示。最后,它似乎对心理治疗也有重要影响。
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引用次数: 0
[Working in Psycho-social Centres: a qualitative research on the experiences of Lombard psychologists.] [在心理社会中心工作:对伦巴第心理学家经验的定性研究]
IF 1 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-11-01 DOI: 10.1708/4386.43837
Rosalba Lamberti, Giulia Lamiani, Chiara Zoppellaro, Pietro Barbetta, Davide Baventore, Giuseppe Cersosimo, Antonella Guarascio, Michele Montecalvo, Elena Vegni

Aims: Interest in the well-being of professionals working in psychiatric patient care contexts is growing in the literature. The aim of this study was to explore the perceived role and work experience of psychologist psychotherapists working in Mental Health Centers (MHC).

Methods: A qualitative research was conducted involving psychologists with a training in psychotherapy working in Lombardy who had at least 3 months of working experience in a MHC. A convenience sample was recruited by email through the Order of Psychologists. From November 2022 to March 2023, 3 focus groups were conducted online and were audio-recorded. In each focus group, a video stimulus was shown, followed by questions on the perceived role and work experience of the participants. Three psychologists analyzed the focus groups' transcripts according to thematic content analysis.

Results: We enrolled 21 psychologists (3 males, with an average age of 44.71 years (SD=9.09) and with an average of 8.49 (SD=8.81) years of work in MHC). Four themes emerged: epistemology of care, services' organization, role of the psychologist and work experience of the psychologist. Results suggest that the epistemology of care embraced, even implicitly, in the MHC contributes to influence the organization of services, the role of the psychologists and their work experience. In MHCs with a biopsychosocial epistemology, the psychologists felt their role was acknowledged and valued by the care team. This leads to experiences of valorization and appreciation.

Discussion and conclusions: Results highlight the importance of the epistemology of care in influencing organization of services and the perceived role and work experience of the psychologists. However, it is also possible that a more circular relationship between the different levels exists, whereby organizational practices could also influence the epistemology of care and the perceived role and work experience of the psychologist. The variety of experiences, within the same Region, suggest that there is a possible cultural and organizational autonomy in MHCs. A reflection on the epistemology of care and organizational practices adopted in MHCs is needed to promote psychologists' well-being at work.

目的:在精神病人护理环境中工作的专业人员的福祉的兴趣在文献中不断增长。本研究的目的是探讨在心理健康中心工作的心理治疗师的感知角色和工作经验。方法:对在伦巴第接受过心理治疗培训的心理学家进行定性研究,这些心理学家在MHC至少有3个月的工作经验。通过心理学家协会的电子邮件招募了一个方便的样本。从2022年11月至2023年3月,在线进行了3次焦点小组调查,并进行了录音。在每个焦点小组中,都会播放一个视频刺激,然后是关于参与者感知到的角色和工作经验的问题。三位心理学家根据主题内容分析分析了焦点小组的记录。结果:共纳入心理学家21人,其中男性3人,平均年龄44.71岁(SD=9.09),平均MHC工作年限8.49年(SD=8.81)。出现了四个主题:护理的认识论、服务的组织、心理学家的角色和心理学家的工作经验。结果表明,MHC中所包含的护理认识论,即使是隐含的,也有助于影响服务的组织、心理学家的角色和他们的工作经验。在具有生物心理社会认识论的mhc中,心理学家感到他们的角色得到了护理团队的承认和重视。这导致了价值增值和增值的体验。讨论和结论:结果强调了护理认识论在影响服务组织和心理学家的感知角色和工作经验方面的重要性。然而,不同层次之间也可能存在一种更循环的关系,即组织实践也可能影响护理认识论和心理学家的感知角色和工作经验。同一区域内的各种经验表明,卫生保健中心可能存在文化和组织自治。为了促进心理学家在工作中的幸福感,需要对mhc中采用的护理认识论和组织实践进行反思。
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引用次数: 0
Effects of technostress on the productivity of workers in ICT company: an observational study. 技术压力对ICT企业员工生产力的影响:一项观察性研究。
IF 1 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-11-01 DOI: 10.1708/4386.43839
Giuseppe La Torre, David Shaholli, Maria Vittoria Manai, Marta Chiappetta, Leandro Casini, Rosario Cocchiara

Introduction: Information and communication technologies (ICT) offer many advantages but also have negative aspects. This study explores the level of stress caused by technology and its impact on productivity, analyzing individual perceptions and use of technology.

Methods: This observational study used a questionnaire validated by Tarafdar et al., translated into Italian and administered online. Technological stress factors, role stress, and productivity were analyzed using SPSS 27. Multivariate analysis identified relationships between responses and various variables.

Results: The analysis of 1,746 individuals revealed a significant association between techno-overload, techno-invasion, techno-complexity, techno-insecurity, techno-uncertainty, and demographic and work-related variables. These factors affected productivity. Bivariate and multivariate analyses confirmed the interaction between technology, stress, and work efficiency. In particular, the female gender was associated with techno-overload (p=0.04), techno-invasion, and role conflict (p<0.001). Age was correlated with techno-invasion (p=0.001), techno-complexity (p<0.001), role overload (p<0.001), role conflict (p=0.046), and productivity (p=0.018).

Discussion and conclusions: Technology, while useful, can lead to technostress. The study highlights how various technological stress factors impact gender, age, and work-related stress. This observational study evaluates the phenomenon of technostress, both work-related and non-work-related, experienced by 1,746 individuals. The results particularly indicate that different technological stress factors significantly affect women, age, and work-related stress. Continued research is needed in this field to better understand and clarify the epidemiology, clinical presentation, and causes of the condition.

导言:信息和通信技术(ICT)有很多优点,但也有负面影响。本研究通过分析个人对技术的看法和使用情况,探讨技术造成的压力水平及其对工作效率的影响:这项观察性研究使用了经 Tarafdar 等人验证的调查问卷,该问卷被翻译成意大利语,并在网上实施。使用 SPSS 27 对技术压力因素、角色压力和工作效率进行了分析。多变量分析确定了回答与各种变量之间的关系:对 1,746 人进行的分析表明,技术超负荷、技术入侵、技术复杂性、技术不安全性、技术不确定性与人口统计学变量和工作相关变量之间存在显著关联。这些因素都会影响生产率。二元和多元分析证实了技术、压力和工作效率之间的相互作用。特别是,女性性别与技术超负荷(p=0.04)、技术入侵和角色冲突(p讨论与结论:技术虽然有用,但也可能导致技术压力。本研究强调了各种技术压力因素对性别、年龄和工作压力的影响。这项观察性研究评估了 1746 人所经历的技术压力现象,包括与工作相关和非工作相关的压力。研究结果特别表明,不同的技术压力因素对女性、年龄和工作压力有显著影响。该领域需要继续开展研究,以更好地了解和澄清该病症的流行病学、临床表现和病因。
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引用次数: 0
Promoting mental health in military veterans. Methodology and evaluation tools in a pilot study involving an Equine-Assisted Intervention. 促进退伍军人的心理健康。一项涉及马辅助干预的试点研究的方法学和评估工具。
IF 1 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-11-01 DOI: 10.1708/4386.43838
Barbara Collacchi, Chiara Ciacchella, Marta Borgi, Alessandra D'Onofrio, Giorgio Fanelli, Sonia Merolla, Marta Riccio, Paolo Mezzanotte, Stefania Cerino, Francesca Cirulli

Aims: Military veterans exposed to stressful or traumatic events may experience adjustment difficulties in the post-deployment period, developing a high risk of mental health-related issues. Promising complementary practices such as Equine-Assisted Therapy (EAT) are now widely used, although standardized protocols are missing. The present study aimed to develop an EAT standardized intervention.

Material and methods: A total of 16 veterans were enrolled for the study (11 veterans for the EAT group and 5 veterans for the control group). The EAT lasted 9 months and both a quantitative (State-Trait Anxiety Inventory Scale; Hamilton Depression Rating Scale; Symptom Checklist 90 Scale; Warwick Edinburgh Mental Well-Being Scale) and a qualitative evaluation (observations and guided discussions) were carried out.

Results: While standardized scales did not show significant results, the qualitative evaluation revealed improvements in participants' attitudes and behaviors (autonomy, self-confidence, sense of agency), coping strategies, management of anxiety and the gradual overcoming of interpersonal difficulties.

Discussion and conclusion: The EAT intervention was particularly appreciated with a high adherence. The empathetic relationship with the horse allowed the participants to establish positive relationships within the group. A self-awareness process emerged during guided discussions and the EAT intervention allowed veterans to rediscover a new group identity. The intervention methodology proved feasible and sustainable although with important limitations due to the low number of participants, the lack of female veterans and the distance between the equestrian rehabilitation centre and the participant's residence. The present study highlights the potential of the human-horse relationship in managing adjustment difficulties, consolidating coping strategies and developing veterans' interpersonal skills.

目的:暴露于压力或创伤事件的退伍军人可能在部署后时期经历调整困难,产生与心理健康有关的问题的高风险。尽管缺乏标准化的治疗方案,但诸如马辅助治疗(EAT)等有前景的补充疗法目前已被广泛使用。本研究旨在开发一种EAT标准化干预措施。材料与方法:共入组16名退伍军人,其中EAT组11名,对照组5名。EAT持续了9个月,同时使用了定量的(状态-特质焦虑量表;汉密尔顿抑郁评定量表;症状检查表90量表;华威爱丁堡心理健康量表)和定性评估(观察和引导讨论)进行。结果:标准化量表没有显示出显著的结果,而定性评估显示了参与者在态度和行为(自主性、自信心、代理感)、应对策略、焦虑管理和逐渐克服人际关系困难方面的改善。讨论和结论:EAT干预具有很高的依从性,尤其值得赞赏。与马的共情关系允许参与者在群体中建立积极的关系。在引导讨论中出现了自我意识过程,EAT干预使退伍军人重新发现了新的群体身份。干预方法被证明是可行和可持续的,尽管由于参与者人数少,缺乏女性退伍军人以及马术康复中心与参与者住所之间的距离而存在重要的局限性。本研究强调了人马关系在管理适应困难、巩固应对策略和发展退伍军人人际交往能力方面的潜力。
{"title":"Promoting mental health in military veterans. Methodology and evaluation tools in a pilot study involving an Equine-Assisted Intervention.","authors":"Barbara Collacchi, Chiara Ciacchella, Marta Borgi, Alessandra D'Onofrio, Giorgio Fanelli, Sonia Merolla, Marta Riccio, Paolo Mezzanotte, Stefania Cerino, Francesca Cirulli","doi":"10.1708/4386.43838","DOIUrl":"https://doi.org/10.1708/4386.43838","url":null,"abstract":"<p><strong>Aims: </strong>Military veterans exposed to stressful or traumatic events may experience adjustment difficulties in the post-deployment period, developing a high risk of mental health-related issues. Promising complementary practices such as Equine-Assisted Therapy (EAT) are now widely used, although standardized protocols are missing. The present study aimed to develop an EAT standardized intervention.</p><p><strong>Material and methods: </strong>A total of 16 veterans were enrolled for the study (11 veterans for the EAT group and 5 veterans for the control group). The EAT lasted 9 months and both a quantitative (State-Trait Anxiety Inventory Scale; Hamilton Depression Rating Scale; Symptom Checklist 90 Scale; Warwick Edinburgh Mental Well-Being Scale) and a qualitative evaluation (observations and guided discussions) were carried out.</p><p><strong>Results: </strong>While standardized scales did not show significant results, the qualitative evaluation revealed improvements in participants' attitudes and behaviors (autonomy, self-confidence, sense of agency), coping strategies, management of anxiety and the gradual overcoming of interpersonal difficulties.</p><p><strong>Discussion and conclusion: </strong>The EAT intervention was particularly appreciated with a high adherence. The empathetic relationship with the horse allowed the participants to establish positive relationships within the group. A self-awareness process emerged during guided discussions and the EAT intervention allowed veterans to rediscover a new group identity. The intervention methodology proved feasible and sustainable although with important limitations due to the low number of participants, the lack of female veterans and the distance between the equestrian rehabilitation centre and the participant's residence. The present study highlights the potential of the human-horse relationship in managing adjustment difficulties, consolidating coping strategies and developing veterans' interpersonal skills.</p>","PeriodicalId":21506,"journal":{"name":"Rivista di psichiatria","volume":"59 6","pages":"298-305"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social Cognition and Covid-19: a rapid scoping review. 社会认知与 Covid-19:快速范围审查。
IF 1 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-11-01 DOI: 10.1708/4386.43836
Tommaso Barlattani, Simonetta Mantenuto, Chiara D'Amelio, Arianna Di Berardo, Francesco Capelli, Valentina Leonardi, Valentina Socci, Rodolfo Rossi, Alessandro Rossi, Francesca Pacitti

The Covid-19 pandemic has enormously impacted health, the economy, and social organisations worldwide. Public health interventions such as vaccines, protective equipment and social distancing have brought profound changes in the general and clinical population's behaviour, with different levels of adherence to social and health standards. To understand these phenomena, it is essential to know how models and theories of social behaviour influence patterns of adherence to preventive measures in the context of the pandemic. Research on social cognition can explain behavioural variables and their impact on mental well-being, creating the basis for interventions that promote adherence to prevention rules. This PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) rapid review aims to identify and analyse current evidence on the pandemic's impact on social cognition components. First, we conducted a comprehensive literature review and discussed the findings narratively. Tables were constructed, and articles were sorted based on study characteristics. Finally, 14 eligible articles were identified. Our findings suggest that restrictions aimed at stemming infections and social isolation led to changes in patterns of social cognition in clinical and general populations. Among the clinical population, subjects with autism spectrum disorders and Parkinson's disease reported changes in social cognition. Among the general population, older adults and front-line workers also reported variations. Our results suggest that planning-oriented social cognition models could effectively promote adherence to preventive norms. These findings can help develop behavioural intervention models by identifying appropriate approaches for the general population and specific subgroups.

新冠肺炎大流行对全球卫生、经济和社会组织造成了巨大影响。疫苗、防护设备和保持社会距离等公共卫生干预措施使一般人群和临床人群的行为发生了深刻变化,对社会和卫生标准的遵守程度也有所不同。要了解这些现象,就必须了解在大流行病背景下,社会行为模型和理论如何影响遵守预防措施的模式。对社会认知的研究可以解释行为变量及其对心理健康的影响,为促进遵守预防规则的干预创造基础。这项PRISMA-ScR(系统评价和荟萃分析扩展范围评价的首选报告项目)快速审查旨在确定和分析有关大流行对社会认知成分影响的现有证据。首先,我们进行了全面的文献综述,并对研究结果进行了叙述性讨论。构建表格,并根据研究特征对文章进行排序。最终确定了14篇符合条件的文章。我们的研究结果表明,旨在遏制感染和社会隔离的限制导致临床和一般人群的社会认知模式发生变化。在临床人群中,患有自闭症谱系障碍和帕金森病的受试者报告了社会认知的变化。在普通人群中,老年人和一线工作人员也报告了差异。我们的研究结果表明,以计划为导向的社会认知模型可以有效地促进对预防规范的遵守。这些发现可以通过确定适用于一般人群和特定亚群体的适当方法,帮助开发行为干预模型。
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引用次数: 0
Italian Guidelines for the diagnosis and treatment of Fetal Alcohol Spectrum Disorders. [意大利胎儿酒精中毒谱系障碍诊断和治疗指南]。
IF 1 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-09-01 DOI: 10.1708/4360.43508
Mauro Ceccanti, Giovanna Coriale, Daniela Fiorentino, Angela Iannitelli, Luigi Tarani, Marco Fiore

Drinking alcohol during pregnancy can cause congenital disabilities. J. Roquette, P. Lemoine and K.L. Jones were the first to describe these effects. In 1973, Jones and Smith coined the term Fetal Alcohol Syndrome to describe children with facial anomalies, poor growth, and learning difficulties. The caution against drinking during pregnancy has existed for centuries, including in The Bible (Judges 13:3-4). Maternal alcohol consumption is linked to congenital disabilities. To ensure safety, it is advised to abstain from alcohol during pregnancy. Fetal Alcohol Spectrum Disorder (FASD) was observed in paintings from the mid-19th century when artists began depicting moments and characters from everyday life. In 2005-2006, Italy conducted a groundbreaking study on FASD, the first in Europe. The study resulted in valuable research on FASD, contributing to prevention efforts. Unfortunately, diagnosing FASD remains a challenge in Italy. Early diagnosis and treatment are critical, and increasing the number of authorized centers to diagnose FASD is necessary to improve care. Educating ourselves about FASD is the key to creating a world where affected children receive the care they need. These guidelines include nine works dealing with all FASD aspects such as prevention, the effects on cognition, the epidemiology, the diagnostic criteria, the clinical aspects, the general effects on the body, the available treatments and the methods of detecting alcohol abuse in pregnant women.

摘要孕期饮酒可导致先天性残疾。J. Roquette、P. Lemoine 和 K.L. Jones 最早描述了这些影响。1973 年,琼斯和史密斯创造了 "胎儿酒精综合征 "一词,用来描述面部畸形、发育不良和学习困难的儿童。几个世纪以来,人们一直对孕期饮酒持谨慎态度,《圣经》中也有相关记载(《士师记》13:3-4)。孕妇饮酒会导致先天性残疾。为确保安全,建议孕期和哺乳期禁酒。胎儿酒精紊乱症(FASD)的证据还可以在 19 世纪中期的绘画作品中观察到,当时的艺术家开始描绘日常生活中的瞬间和人物。2005-2006 年,意大利开展了一项关于 FASD 的创新研究,这在欧洲尚属首次。该研究对 FASD 进行了有价值的研究,为预防工作做出了贡献。遗憾的是,在意大利,诊断 FASD 仍然是一项挑战。早期诊断和治疗至关重要,为了改善护理,需要增加授权诊断 FASD 的中心数量。本指南由九篇论文组成,涵盖了 FASD 的各个方面,如预防、对认知的影响、流行病学、诊断标准、临床方面、对身体的一般影响、现有治疗方法以及检测孕期酗酒的方法。
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引用次数: 0
Italian Guidelines for the diagnosis and treatment of Fetal Alcohol Spectrum Disorders: multimodal approaches of treatment and intervention. [意大利胎儿酒精谱系障碍诊断和治疗指南:多模式治疗和干预方法]。
IF 1 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-09-01 DOI: 10.1708/4360.43513
Giovanna Coriale, Arianna Barzacchi, Daniela Fiorentino, Luigi Tarani, Marisa Patrizia Messina, Maria Concetta Scamporrino, Giuseppe Ducci, Stefano Cavallari, Marco Fiore, Antonella Cavalieri, Mauro Ceccanti

Fetal Alcohol Spectrum Disorders (FASD) are pervasive disorders that impact various domains of functioning, including self-esteem, familiar and peer relationships, and academic success. The high rate of comorbidity may contribute to delayed diagnosis and treatment. Early diagnosis and intervention that aim at primary symptoms may prevent secondary disabilities and improve the outcomes. No intervention emerged as maximally effective across all symptoms and domains. Consequently, the complex pathophysiology of FASD emphasizes the need for individualized assessment and treatment by using a multimodal approach to intervention.

摘要。胎儿酒精谱系障碍(FASD)是一种普遍存在的疾病,会影响各方面的功能,包括自尊、家庭和同伴关系以及学业成就。合并症的高发率可能会导致诊断和治疗的延迟。早期诊断和针对主要症状的干预可以预防继发性残疾并改善治疗效果。目前还没有一种干预措施能在所有症状和领域发挥最大功效。因此,FASD 复杂的病理生理学强调了采用多模式干预方法进行个性化评估和治疗的必要性。领养、产前酒精暴露、干预、胎儿酒精谱系障碍、胎儿酒精综合征、治疗。
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引用次数: 0
Italian Guidelines for the diagnosis and treatment of Fetal Alcohol Spectrum Disorders: epidemiology [意大利胎儿酒精谱系障碍诊断和治疗指南:流行病学]。
IF 1 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-09-01 DOI: 10.1708/4360.43516
Mauro Ceccanti, Giovanna Coriale, Daniela Fiorentino, Luigi Tarani, Marisa Patrizia Messina, Mario Vitali, Marco Fiore, Philip A May

Fetal alcohol spectrum disorders (FASD) are a significant global challenge characterized by complex diagnosis and research. The diagnostic process is complicated due to overlapping symptoms with other conditions, as well as factors such as maternal nutrition, socioeconomic status, and mental health, which can affect the severity of FASD traits differently in individuals. Risky drinking behaviors are prevalent in young adults, especially those aged 20-24, which coincides with high rates of unplanned pregnancies, increasing the risk of FASD. Specific subpopulations, such as children in care facilities and specialized clinical settings, face higher FASD prevalence. Preventing alcohol consumption during pregnancy is crucial for maternal and fetal well-being. Yet approximately 10% of women worldwide continue to drink during pregnancy, with notably high rates in the European Region. Young adults, especially in countries like Italy, continue to consume alcohol despite legal restrictions, mirroring the drinking patterns of men and raising concerns for fetal health and development. Research findings regarding alcohol’s risks during pregnancy vary, emphasizing the need for increased education on this issue. Ethylglucuronide (EtG) is a reliable biomarker for monitoring alcohol intake during pregnancy, suggesting regular urine examinations throughout each trimester. Proactive education campaigns, particularly in educational institutions, and establishing early diagnosis centers are recommended to address FASD effectively.

摘要胎儿酒精谱系障碍(FASD)是一项重大的全球性挑战,其特点是诊断和研究复杂。由于症状与其他疾病重叠,加上母亲的营养状况、社会经济地位和心理健康等因素,诊断过程十分复杂,这些因素可能会对不同个体的 FASD 特征的严重程度产生不同的影响。与饮酒有关的危险行为在青壮年中十分普遍,尤其是在 20-24 岁的人群中,这与意外怀孕率高的情况相吻合,从而增加了罹患 FASD 的风险。特定的亚人群,如护理机构和特殊临床环境中的儿童,面临着更高的 FASD 患病率。防止孕期饮酒对孕产妇和胎儿的健康至关重要。然而,全球约有 10%的妇女在怀孕期间继续饮酒,欧洲地区的比例更高。特别是在意大利等国,尽管有法律限制,但年轻成年人仍在继续饮酒,这与男性的饮酒模式如出一辙,引起了人们对健康和胎儿发育的担忧。有关怀孕期间饮酒风险的研究结果各不相同,这突出表明有必要就这一主题开展更多教育。乙基葡萄糖醛酸(EtG)是监测孕期酒精摄入量的可靠生物标志物,建议在每个孕期定期进行尿检。建议开展积极主动的教育活动,特别是在教育机构,并建立早期检测中心,以有效解决 FASD 问题。
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引用次数: 0
Italian Guidelines for the diagnosis and treatment of Fetal Alcohol Spectrum Disorders: detecting alcohol drinking during pregnancy. [意大利胎儿酒精谱系障碍诊断和治疗指南:孕期饮酒检测]。
IF 1 4区 医学 Q4 PSYCHIATRY Pub Date : 2024-09-01 DOI: 10.1708/4360.43514
Giampiero Ferraguti, Francesca Fanfarillo, Simona Nicotera, Sergio Terracina, Clementina Moschella, Alessandro Mattia, Maria Chiara David, Simona Pichini, Giovanna Coriale, Daniela Fiorentino, Mauro Ceccanti, Maria Grazia Piccioni, Luigi Tarani, Marco Fiore

Fetal Alcohol Spectrum Disorders (FASD) is an encompassing term used to describe a range of afflictions brought about by the consumption of alcohol during gestation. The detrimental effects primarily manifest in the central nervous system, growth, and distinctive facial features. Given that there are no known treatments for FASD, the meticulous screening for this condition in the earliest stages of pregnancy bears immense significance, ensuring the avoidance of the grievous consequences stemming from exposure to alcohol in utero. Screening measures for FASD encompass the assessment of alcohol biomarkers such as Phosphatidylethanol (PEth) in the maternal bloodstream, Fatty Acid Ethyl Esters (FAEEs) in the meconium, and Ethyl Glucuronide (EtG) in the meconium, maternal urine and hair. In particular, urinary EtG is highly sensitive and could be routinely used in pregnant women for detecting also occasional drinking. Questionnaire evaluations including AUDIT-C, T-ACE, and TWEAK, alongside a detailed Food Diary method to identify alcohol misuse and high-risk pregnancies, are also available. However, these questionnaires might provide an inadequate reflection of alcohol consumption in women due to their inclination to dissemble to comply with prevailing sociocultural expectations. Hence, this comprehensive review advocates for the indispensable integration of alcohol biomarkers detection in the course of pregnancy monitoring, as it constitutes a valuable tool for facilitating FASD screening.

摘要。胎儿酒精紊乱症(FASD)是一个包罗万象的术语,用于描述妊娠期饮酒导致的一系列疾病。其危害主要表现在中枢神经系统、生长发育和独特的面部特征上。由于目前尚无治疗 FASD 的方法,因此在孕早期对这种疾病进行细致的筛查意义重大,可有效限制子宫内酒精暴露造成的严重后果。FASD 筛查措施包括评估酒精生物标记物,如母体血液中的磷脂酰乙醇(PEth)、胎粪中的脂肪酸乙酯(FAEE)以及胎粪、母体尿液和毛发中的乙基葡萄糖醛酸(EtG)。尤其是尿液中的 EtG 灵敏度很高,可用于常规检测孕妇是否偶尔摄入。此外,还可通过 AUDIT-C、T-ACE 和 TWEAK 等问卷进行评估,并通过食物日记来识别酗酒和高危妊娠。然而,这些问卷可能无法充分反映妇女的饮酒情况,因为她们倾向于撒谎以迎合普遍的社会文化期望。因此,这项工作强调了在妊娠监测期间进行酒精生物标志物检测是不可或缺的,是促进早期发现可能的 FASD 的宝贵工具。
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